CN101461849A - Biological Chinese herbal medicine bedsore powder - Google Patents

Biological Chinese herbal medicine bedsore powder Download PDF

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Publication number
CN101461849A
CN101461849A CNA2007101157772A CN200710115777A CN101461849A CN 101461849 A CN101461849 A CN 101461849A CN A2007101157772 A CNA2007101157772 A CN A2007101157772A CN 200710115777 A CN200710115777 A CN 200710115777A CN 101461849 A CN101461849 A CN 101461849A
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bedsore
chinese herbal
herbal medicine
powder
biological chinese
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CNA2007101157772A
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Chinese (zh)
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曲奕
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Individual
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Abstract

The invention relates to biological Chinese herbal medicine bedsore powder, which comprises the following main compositions: chitin, radix scutellariae, Coptis chinensis, tinospora roots, polyhexamethylene guanide and glycerol. The composite biological Chinese herbal medicine bedsore powder is prepared by mixing the main compositions according to proportion and drying and grinding the mixture. The biological Chinese herbal medicine bedsore powder can be used for antiphlogosis and odynolysis, antibacterium and disinfection, dry and comfortable function and anti-cohesion of multiple types of bedsore, and for promoting cure and repair of the skin tissue. The biological Chinese herbal medicine bedsore powder has the advantages that: firstly, the biological Chinese herbal medicine bedsore powder has good biocompatibility and is suitable for the skin suffering from multiple types of bedsore; secondly, the biological Chinese herbal medicine bedsore powder has good effects on antibacterium, antiphlogosis and odynolysis, high water rate, and good tensile strength at break and tear strength, prevents overflow of exudate, promotes formation of granulation tissue and epithelial tissue, and is quick to cure and repair the skin tissue; thirdly, the biological Chinese herbal medicine bedsore powder has good flexibility, swellabitity, permeability and biological safety; fourthly, the product has good performance and low cost, and is convenient to use; and fifthly, the biological Chinese herbal medicine bedsore powder prepared by special technology is an ideal product for treating trauma and bedsore.

Description

Biological Chinese herbal medicine bedsore powder
Technical field the present invention relates to a kind of biological Chinese herbal medicine bedsore powder, and its main component is that chitin, Radix Scutellariae, Rhizoma Coptidis, Jin Guolan, polyhexamethylene guanidine, glycerol are mixed in proportion, and the oven dry back is ground and made compound bio Chinese herbal medicine bedsore powder.Can be used for anti-inflammatory analgetic, antibiotic and sterilizing, dry and comfortable anti, the healing of promotion skin histology and the reparation of all kinds decubital ulcer.Decubital ulcer has another name called pressure ulcer, is aged crowd's frequently-occurring disease and commonly encountered diseases, can be divided into types such as exogenous, constitutional, endogenous, Secondary cases.Its cause of disease mainly is the body surface part, because of the long-term bed pressurized, causes that neurotrophy disorder and blood circulation are not smooth, causes the soft tissue continuous ischemia, causes skin resistance to descend and causes.Existing bedsore powder kind is a lot, and the performance of anti-inflammatory analgetic, antibiotic and sterilizing, healing and reparation differs, and the branch of high, medium and low effect is arranged.And skin, angle conjunctiva and muscle there are zest, toxic to keratinocyte and fibroblast, do not have the good biological safety.Therefore, people wish to have a kind of anti-inflammatory analgetic, antibiotic and sterilizing, healing and reparation and biological safety good always, the bedsore powder product of biological medium-height grass Types of Medicine.
Background technology the object of the present invention is to provide that a kind of to overcome existing procucts insufficient, the bedsore powder product of biological medium-height grass Types of Medicine.Have good biocompatibility, water rate height, pull apart good with tearing strength, stop that sepage is overflowed, analgesic antiphlogistic, antibacterial, the dry and comfortable anti of sterilization, promote the formation of granulation tissue and epithelial tissue, the ideal product that skin histology healing and repair characteristics such as fast is a wound, treat patients with decubitus.
Summary of the invention main points of the present invention are to select suitable component, and rationally are mixed, and form biological Chinese herbal medicine bedsore powder through a series of modern biotechnologies.
The prescription following (component and percentage by weight % thereof) that the present invention selects: chitin (20.0-30.0); Radix Scutellariae (10.0-20.0); Rhizoma Coptidis (10.0-20.0); Gold fruit blue (10.0-20.0); Polyhexamethylene guanidine (3.0-5.0); Glycerol (3.0-5.0).
Chitin is inhibited to the growth of various bacteria, shows similar antibiotic feature.Chitin is all inhibited to experimental strains such as staphylococcus epidermidis, staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, even the Candida albicans that general antibiotic is difficult to suppress is also had inhibitory action.Divided greatly chitin by self with positive charge and the interaction of the entrained negative charge of microbial cell film, destroy the bacteria cell wall original structure, cause the leakage of cell component and play antibacterial action.And micromolecular chitin has anionic biomacromolecule generation similar " flocculation " effect by penetrating in the cell, upsets the normal physiological function of cell, the biosynthesis of blocking dna, thereby breeding and the growth of inhibition antibacterial.The wound healing process mainly comprises platelet aggregation, blood coagulation, fibrin formation, inflammatory reaction generation, substrate variation, cell proliferation and regeneration, repair of damaged tissues and process such as reinvent.Chitin can promote epithelial regeneration, promotes wound healing by mediated cell propagation, by the acute inflammatory response of gentleness, attracts a large amount of polymorphonuclear cells and macrophage to remove fragment of tissue and blood clot.Chitin can promote fibrocellular migration, and stromal cell is had chemotactic, migration, activation, and quickens cell proliferation and tissue remodeling process, promotes skin tissue recovering.Catabolite N-the acetylglucosamine (NAG) of chitin is repaired extremely important to the cicatrix of tissue.Itself has analgesic effect chitin.Simultaneously, chitin mainly is that erythrocytic agglutination is realized pain relieving by the interaction between itself and the erythrocyte membrane.Its pain relieving mechanism is: the receptor of the neuraminic acid residue that positively charged chitin and cell surface are electronegative interacts, and promotes hematoblastic gathering, activates blood coagulation system, and crosslinked erythrocyte forms clot.And chitin has tangible film formation effect, can accelerating wound healing and prevent massive hemorrhage.
Polyhexamethylene guanidine is the derivant of high molecular polymer, as the main sterilizing sterile components, guanidine radicals in this component has very high activity in polyreaction, make polymeric derivative be electropositive, so be easy to be usually electronegative each bacterioid, viral adsorbed, thereby the splitting function that has suppressed antibacterial, virus, make antibacterial, virus lose reproductive function, the thin film of polymer formation in addition, stopped up the respiration channel of microorganism, made microorganism suffocate the power of losing one's life and reach sterilization effect.
Radix Scutellariae, Rhizoma Coptidis, gold fruit indigo plant have antimicrobial and anti-inflammation efficacy.Glycerol is plasticizer, has good pliability, dilatancy and airing function.
The preparation method of product of the present invention is:
1). with rough chitin, Radix Scutellariae, Rhizoma Coptidis, the blue mixing of gold fruit.
2). poly hexamethylene guanidine derivative and glycerol are mixed.Spray equably in the said mixture surface.
3) behind the sterilizing-drying, ball mill pulverizing becomes biological Chinese herbal medicine bedsore powder.Carry out packing.Check, warehousing after passing.
The present invention has the following advantages: 1) the bedsore powder product of biological medium-height grass Types of Medicine.Have good biocompatibility, the skin of various decubital ulcers all is fit to.2) anti-inflammation good analgesic effect, water rate height, pull apart good with tearing strength, stop sepage to be overflowed, promote the formation of granulation tissue and epithelial tissue, skin histology healing and repair fast.3) have good pliability, dilatancy and airing function and biological safety.4) good product performance, price are low, easy to use.5) ideal product that the biological Chinese herbal medicine bedsore powder of special process preparation is a wound, treat patients with decubitus.
The present invention is described in further detail below in conjunction with embodiment for the specific embodiment:
Be configured according to following table institute column data (percentage by weight %) and described step thereof:
Prescription one:
Chitin (20.0-30.0); Radix Scutellariae (10.0-20.0); Rhizoma Coptidis (10.0-20.0); Gold fruit blue (10.0-20.0); Polyhexamethylene guanidine (3.0-5.0); Glycerol (3.0-5.0).
Prescription two:
Chitin (20.0-30.0); Radix Scutellariae (10.0-15.0); Rhizoma Coptidis (10.0-15.0); Gold fruit blue (10.0-20.0); Polyhexamethylene guanidine (3.0-4.0); Glycerol (3.0-4.0).
Figure A200710115777D00042
Prescription three:
Chitin (25.0-30.0); Radix Scutellariae (10.0-15.0); Rhizoma Coptidis (15.0-20.0); Gold fruit blue (10.0-15.0); Polyhexamethylene guanidine (4.0-5.0); Glycerol (4.0-5.0).
Figure A200710115777D00043
Prescription four:
Chitin (22.0-28.0); Radix Scutellariae (15.0-18.0); Rhizoma Coptidis (12.0-19.0); Gold fruit blue (13.0-17.0); Polyhexamethylene guanidine (3.0-4.0); Glycerol (4.0-5.0).
Figure A200710115777D00044

Claims (2)

1, a kind of biological Chinese herbal medicine bedsore powder, its main component are that chitin, Radix Scutellariae, Rhizoma Coptidis, Jin Guolan, polyhexamethylene guanidine, glycerol are mixed in proportion, and the oven dry back is ground and made; It is characterized in that having following prescription (component and percentage by weight % thereof): chitin (20.0-30.0); Radix Scutellariae (10.0-20.0); Rhizoma Coptidis (10.0-20.0); Gold fruit blue (10.0-20.0); Polyhexamethylene guanidine (3.0-5.0); Glycerol (3.0-5.0).
2, the preparation method of the described biological Chinese herbal medicine bedsore powder of a kind of claim 1 is characterized in that having following step:
1). with rough chitin, Radix Scutellariae, Rhizoma Coptidis, the blue mixing of gold fruit;
2). poly hexamethylene guanidine derivative and glycerol are mixed, spray equably in the said mixture surface;
3) behind the sterilizing-drying, ball mill pulverizing becomes the chitin bedsore powder, carries out packing, check, warehousing after passing.
CNA2007101157772A 2007-12-19 2007-12-19 Biological Chinese herbal medicine bedsore powder Pending CN101461849A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA2007101157772A CN101461849A (en) 2007-12-19 2007-12-19 Biological Chinese herbal medicine bedsore powder

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA2007101157772A CN101461849A (en) 2007-12-19 2007-12-19 Biological Chinese herbal medicine bedsore powder

Publications (1)

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CN101461849A true CN101461849A (en) 2009-06-24

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011135578A1 (en) * 2010-04-28 2011-11-03 Chetan Balar Composition comprising chitin and tinosporin for use in the treatment of viral diseases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011135578A1 (en) * 2010-04-28 2011-11-03 Chetan Balar Composition comprising chitin and tinosporin for use in the treatment of viral diseases

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