CN101856227A - Breast electrical impedance fault imager based on mobile phone platform - Google Patents

Breast electrical impedance fault imager based on mobile phone platform Download PDF

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Publication number
CN101856227A
CN101856227A CN201010203015A CN201010203015A CN101856227A CN 101856227 A CN101856227 A CN 101856227A CN 201010203015 A CN201010203015 A CN 201010203015A CN 201010203015 A CN201010203015 A CN 201010203015A CN 101856227 A CN101856227 A CN 101856227A
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China
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electrode
electrical impedance
chip microcomputer
mammary gland
detection
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CN201010203015A
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CN101856227B (en
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刘冉
刘静
金翠云
申成虎
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Tsinghua University
Beijing University of Chemical Technology
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Tsinghua University
Beijing University of Chemical Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/43Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312Breast evaluation or disorder diagnosis

Abstract

The invention relates to a breast electrical impedance fault imager based on a mobile phone platform, belonging to the technical field of medical detecting instruments and biological detection. The fault imager comprises a breast detection component, an electrical impedance detection circuit and a mobile phone comprising data result display and analysis software, wherein the electrical impedance detection circuit comprises a singlechip, a frequency generator, a filtering amplifying circuit, an analog switch, an electrode group and an amplitude phase detection chip. The invention can make patients periodically checked and early diagnosed without going to hospitals and particular working environments by adopting a biological electrical impedance fault image detection technology and widely used mobile phones, and a personal medical record library can be saved so as to exchange with doctors in time and check patient's conditions. The imager has the characteristics of small volume, high safety, simple operation, low cost and the like and is especially suitable for household use.

Description

Breast electrical impedance fault imager based on cell phone platform
Technical field
The present invention relates to a kind of electrical impedance tomography (EIT) equipment and measuring technique, particularly mobile phone technique and USB2.0 mechanics of communication belong to medical detecting Instrument and technical field of biological.
Background technology
Find that according to the investigation of Chinese population association China's breast cancer incidence constantly rose in recent years, and become one of maximum disease in the women's diseases.Breast carcinoma is one of tumor disease, and is the same with other tumor diseases, to breast carcinoma to early find, the policy of diagnosis, early treatment early.But China's breast cancer disease inspection has a lot of drawbacks at present, and China's women with breast cancer morbidity is never taken a turn for the better.
Breast carcinoma be the modal malignant tumor of women it, its sickness rate especially in the obvious ascendant trend of Asian countries, has become one of principal disease of serious harm WomanHealth and life in the world.In recent years the growth rate of China's breast cancer incidence exceeds national 1-2 percentage point occurred frequently, and is obvious rejuvenation trend, and ten thousand women suffered from breast cancer surplus China had 20 every year.And the therapeutic effect of breast carcinoma depends primarily on the morning and evening of state of an illness diagnosis.Reason is the less generation metastasis of the tumor cell of breast carcinoma of early stage, and most treatments better.But the state of an illness more tumor cell generation metastasis during late period, and destroy other organs.Cause therapeutic effect poor, the mortality rate height.Therefore, the early discovery of breast carcinoma and diagnosis are significant for the probability of the generation that reduces cystic hyperplasia of breast, increase patient existence.
And breast cancer detection at present must go to hospital to detect, and a lot of women can not guarantee regularly to go hospital's health check-up, though thereby the early stage cure rate that has caused breast carcinoma than higher, but a lot of people misses the early treatment, late very difficult treatment when diagnosing out breast carcinoma.
Common mammary gland detection method has key target X-ray examination, CT examination, magnetic resonance (MRI) inspection, ultrasonic examination and positron emission (PET) imaging, infrared transillumination imaging, liquid crystal thermography imaging at present.And the clinical common method of China is key target X-ray examination and ultrasonic examination.
Since the invention sixties in last century aluminum target X line machine, the mammary X-ray diagnosis develops rapidly, becomes the most frequently used mammary gland detection method gradually.Especially the digitized photography technology incorporates the X ray detection, makes breast X-ray can check out more not perceived cancer, and the wide dynamic range of image, and contrast resolution also improves greatly.But X ray is easy to fail to pinpoint a disease in diagnosis for the little cancer near thoracic wall and dense form mammary gland.And the ionization of X ray is harmful, may bring out cancer.Often contact the probability that X ray meeting induced tumor produces.X line photography still has higher false positive rate for the diagnosis of breast tumor, in the U.S. because the uncertain result of X line photography carries out having only 25%~29% to be diagnosed as breast carcinoma among the women of biopsy.
Ultrasonic examination can clear demonstration mammary gland in the form of lump in each layer soft tissue and the mammary gland, be a kind of valuable detection method for the diagnosis of mastopathy.Particularly the dense form mammary gland of young woman and did the mammary gland plasty after evaluation.Especially after introducing color doppler ultrasonography, make ultra sonic imaging can obtain the two dimensional image and the colorful blood feature of fine definition, check noinvasive, quick, repeatability is strong, resolution is high, differentiate that capsule and reality lump accuracy rate are up to more than 90%.But ultrasonographic limitation is the accuracy of checking and depends on employed equipment and inspecting doctor's personal experience to a great extent.The probe of 10MH has improved the recall rate to the cluster microcalciffcation in addition, but still it is reliable to be not so good as X ray.
Electrical impedance imaging is arranged at present, and (electrical impedance tomography, EIT) technology also can detect breast carcinoma.The electrical impedance tomography technology is to organize the difference of electrical characteristic parameter (as resistivity, dielectric constant) according to interior of articles, by its surface is applied safe exciting current or voltage, the voltage or the current signal on Measuring Object surface are known the distribution of interior of articles electrical characteristic parameter simultaneously, and then reconstruct the image of reflection internal structure of body.This is significant to organism internal electrical The Characteristic Study, and this image has not only comprised abundant anatomic information, and can obtain the information that the electrical characteristics of some tissue and organ change with its pathology, states of physiologic function.Medical research shows that when disease took place, the functional variation of linked groups and organ often will be prior to organic disease and other clinical symptoms.Through after certain functional compensation phase or incubation period, develop into organic disease, begin to occur tissue and organ structure variation or other clinical symptoms.When the functional variation of tissue and organ, cause the conductance property of its tissue also to change, significant change is arranged during electricity consumption impedance detection technology for detection.And the human body structure that key target X-ray examination and ultrasonic examination technology etc. provide has only when the disease generation, and to form organic disease, when the structure of linked groups and organ changes (as forming a certain size tumor), just can provide diagnostic result.Breast carcinoma is the same with other tumor disease to need early discovery, early treatment.Compare with other detection technique, the electrical impedance detection technique is more suitable for the early diagnosis of breast carcinoma.And this mode is harmless, can repeatedly measure, and reuses, can become to the patient carry out for a long time, on-line monitor and can not cause damage or bring hospital's custodial care facility of discomfort to the patient.Add with low costly, do not require special working environment etc., thereby be a kind of comparatively ideal, medical imaging technology with broad prospect of application.And the external existing instrument that utilizes electrical impedance imaging technology for detection mammary gland tissue, but instrument is big and shortcoming such as instrument cost height, and inconvenience is used in family.
Summary of the invention
The objective of the invention is to utilize present widely used mobile phone, for family and individual provide a kind of volume the breast electrical impedance fault imager based on cell phone platform little, simple to operate, make the patient need not hospital and special working environment can be made regular check on easily, and can preserve the IMR storehouse, so that in time exchange and check the state of an illness with the doctor.
Technical scheme of the present invention is as follows:
A kind of breast electrical impedance fault imager based on cell phone platform is characterized in that: described imager comprises mammary gland detection part, impedance detection circuitry, contains the hands machine of data result demonstration and analysis software; Described mammary gland detection part is " medicated bra shape ", and arranges the triple electrode group according to udder texture, is respectively mammary areola region electrode layer, middle part electrode layer and edge electrode layer, every layer electrode uniform distribution; Described impedance detection circuitry comprises single-chip microcomputer, frequency generator, filter amplification circuit, analog switch and the amplitude-phase detection chip that contains electrical impedance detection and process software; Impedance detection circuitry is the center with described single-chip microcomputer, the outfan of single-chip microcomputer is connected with the input of frequency generator by control circuit, the frequency signal of frequency generator output generates ac current signal through after the filter amplification circuit, ac current signal is inputed to a pair of adjacent electrode in one deck electrode group by analog switch by single-chip microcomputer, and by an electrode in this counter electrode ac current signal is inputed to mammary gland tissue, and another electrode links to each other with power supply ground; Voltage signal by obtain mammary gland tissue with the remaining electrode in one deck electrode group is input to the amplitude-phase detection chip by the Single-chip Controlling analog switch with voltage signal again, after transforming signal is input to single-chip microcomputer; The a pair of adjacent electrode of following one deck of the selected electrode group of reuse analog switch comes the input AC current signal after single-chip microcomputer has detected one deck electrode group, detects the electrical impedance of this layer; Use the same method and detected each electrode layer; After having detected, single-chip microcomputer changes into picture signal to signal through image reconstruction algorithm; Described single-chip microcomputer carries out two-way communication by communication module and described mobile phone, picture signal is sent to mobile phone, and show on mobile phone; The frequency of described frequency generator output is 1kHz~100kHz.
Technical characterictic of the present invention also is: described mammary gland detection part is divided into internal layer and skin, and internal layer is a latex material, and described electrode group is arranged on the internal layer, and described skin is an overcoat, arranges electrode cable between internal layer and skin.
The electrode density of described mammary areola region electrode layer and edge electrode layer is greater than the electrode density of middle part electrode layer.
Communication module of the present invention adopts USB2.0 or bluetooth.
The present invention compared with prior art, have the following advantages and the salience effect: 1. the present invention uses bio-electrical impedance faultage image (EIT) detection technique in breast cancer detection, this technology is harmless to health, can repeatedly measure, reuse, and equipment cost is cheap, detects characteristics such as simple and no environment constraint, is expected to become the effective ways of breast carcinoma generaI investigation.2. this device is applicable to that family uses, and characteristics such as little, the simple to operate and inspection fee of volume is cheap are arranged, and does not go to hospital just can make regular check on to oneself easily.This device solves owing to traditional view, the examination in hospital time is long, inspection fee is expensive etc., and reason delays the problem of making regular check on.3. this device has used general mobile phone to be control, shows, store and the parts of communication, and generally mobile phone just can be finished function, and the user only needs detection part and cell phone software, can use this equipment, has significantly reduced component costs.4. use mobile phone storage capacity and ability to communicate in this device, made testing result save as the IMR storehouse, exchanged and checked the state of an illness easily with the doctor.
Description of drawings
Fig. 1 is a circuit structure theory diagram of the present invention.
Fig. 2 is the perspective plan view (electrode cable omits) of mammary gland detection part embodiment.
Fig. 3 has an X-rayed plan view (electrode cable omits) for mammary gland detection part embodiment.
Fig. 4 is breast edge and mammary areola district sketch map.
Fig. 5 is a mammary gland detection part part tomograph.
Fig. 6 is an overall structure sketch map of the present invention.
Fig. 7 is the electrical impedance detection of single-chip microcomputer and the flow chart of process software.
Fig. 8 is the data result demonstration of mobile phone and the FB(flow block) of analysis software.
The drawing explanation
1-mammary gland detection part skin; 2-mammary gland detection part internal layer; The 3-electrode; 4-mammary areola district; The 5-edge; The 6-electrode cable; 7-electrode protection cover; 8-mammary gland detection part; The 9-impedance detection circuitry; 10-hands machine; The 11-USB line.
The specific embodiment
Be further described below in conjunction with concrete structure, measuring principle, process and the embodiment of accompanying drawing this device.
Fig. 1 is the structure principle chart of the mammary gland point impedance detector based on cell phone platform of the present invention.This imager comprises electrical impedance detection part, impedance detection circuitry and mobile phone.The mammary gland detection part is " medicated bra shape ", and arranges the electrode group in the above.And impedance detection circuitry comprises single-chip microcomputer, frequency generator, filter amplification circuit, analog switch and the amplitude-phase detection chip that contains electrical impedance detection software.
Fig. 2 and Fig. 3 are the perspective view of mammary gland detection part embodiment, can conveniently check the distribution of electrodes situation.The mammary gland detection part is made up of mammary gland detection part internal layer and mammary gland detection part skin.Mammary gland detection part internal layer is that latex material is formed, and major function is adsorbed on the mammary gland electrode for inserting electrode and absorption skin.Electrode cable is arranged between mammary gland detection part internal layer and the mammary gland detection part skin.The outer major function of mammary gland detection part is that the shield electrode lead is not damaged.Distribution of electrodes is on internal layer.The electrode group of present embodiment is divided into 5 layers of cloth, and one deck electrode, i.e. edge electrode layer are arranged in the edge of breast; Arrange one deck electrode, i.e. mammary areola region electrode layer on the edge in breast mammary areola district; Be called the middle part electrode layer between the edge of breast and the mammary areola district, the middle part also can evenly be divided into 2~4 layers of electrode (present embodiment is divided into 3 layers with the middle part).Fig. 4 is seen in breast edge and mammary areola district.For convenience's sake, edge electrode layer called after ground floor, the 5th layer of mammary areola region electrode layer called after, the middle part is the 2nd layer of called after successively, the 3rd layer and the 4th layer.The 1st layer of electrode group is by 32 electrode uniform distribution, and other layer is 16 electrode uniform distribution.Because the breast carcinoma common site is mammary areola district and edge, thus closeer in mammary areola district and edge distribution of electrodes, make the detection effect quite a lot of.And common electrode is distributed as 16,32 or 64 electrodes at present.The 1st layer is the edge, makes distribution of electrodes closeer with 32 electrodes, makes the detection effect better.The 5th floor is the mammary areola district, and is less because of mammary areola district radius, also can obtain tomograph preferably with 16 electrodes.
Fig. 5 is a mammary gland detection part part tomograph.Distribution of electrodes is on mammary gland detection part internal layer.Be to put, be inserted in again on the mammary gland detection part internal layer by the electrode protection cover.Among Fig. 59 is the electrode protection cover, is made up of circular, nonelastic, insulant.Electrode protection cover major function is that shield electrode is not damaged when mammary gland detection part internal layer stretches.Arrange lead between mammary gland detection part internal layer and mammary gland detection part skin, because wire arrangements is a lot, and lead directly is arranged in outer being easily damaged, so add one deck mammary gland detection part outer layer protection lead.
Impedance detection circuitry comprises single-chip microcomputer, frequency generator, filter amplification circuit, analog switch and amplitude-phase detection chip.It is to be the center with the single-chip microcomputer that electrical impedance detects, and whole process is finished automatically by mcu programming.Single-chip Controlling frequency generator when beginning to detect makes the ac current signal between the frequency generator output 1-100KHz.The ac current signal of frequency generator output is through the alternating current of generation 1mA after the filter amplification circuit, and the amplitude of alternating current keeps inconvenience in whole testing process.When stable alternating current was exported, the Single-chip Controlling analog switch was selected two adjacent electrodes in the ground floor.One of them electrode input AC current signal, another electrode link to each other with power supply ground as reference voltage.Select the voltage signal that obtains mammary gland tissue with the remaining electrode of one deck by the Single-chip Controlling analog switch again.By the Single-chip Controlling analog switch voltage signal is input to the amplitude-phase detection chip again, after transforming, signal is input to single-chip microcomputer and stores.The a pair of adjacent electrode of following one deck of the selected electrode group of reuse analog switch comes the input AC current signal after single-chip microcomputer has detected one deck electrode group, detects the electrical impedance of this layer.Use the same method and detected each electrode layer.After having detected, single-chip microcomputer changes into picture signal to signal through image reconstruction algorithm.Single-chip microcomputer carries out two-way communication by communication module and mobile phone, picture signal is sent to mobile phone, and show on mobile phone.
When selecting the communication modes of single-chip microcomputer and mobile phone, we can select the communication modes of bluetooth or USB2.0.
When selecting the bluetooth communication mode, need to add bluetooth communication circuit and power-supply system, in circuit design because of using more chip, the circuit more complicated.When selecting the USB2.0 communication modes,, USB can directly power because of having the access of 5V voltage to need not to add in addition power-supply system.And the singlechip chip of existing at present integration USB 2.0 communications protocol can be directly and the logotype of USB2.0 interface, and is easy to use.
On the design, select the USB2.0 communication modes for use, so when single-chip microcomputer is selected for use, use the EZ-USB FX2 single-chip microcomputer CY7C68013 of Cypress company.EZ-USB FX2 is first USB2.0 integrated peripheral controller that industry is released, and integrated enhancement mode 8051 single-chip microcomputers, can directly use USB interface and 8051 microcontroller communications.And at present smart mobile phone much all has USB interface, and need not translation interface can be directly and the logotype of this device.The adjustable frequency generator is selected the AD9850 chip for use.This chip includes DDS system able to programme and high-speed comparator, can realize the frequency synthesis of digital programming Control.In the 1-100KHz frequency range, select 100 frequencies, control AD9850 by mcu programming and send frequency signal.Again through generating the alternating current of 1mA after the filter amplification circuit.The alternating current input that generates is input on the mammary gland tissue by electrode, makes other electrodes obtain voltage signal.Voltage signal is input to amplitude-phase measurement chip by electrode and comes inverted signal.Chip is selected the AD8302 chip for use.The integrated circuit of this chip is integrated RF/IF amplitude and phase measurement, can measure from low frequency to the 2.7GHz frequency range simultaneously in two input signals amplitude than and phase contrast.This device is integrated in two logarithmic detectors of precision-matched on the chip piece, thereby error source and associated temperature drift can be reduced to bottom line.This device is when carrying out amplitude measurement, and its dynamic range can expand to 60dB, and the phase measurement scope then can reach 180 degree.Store when the amplitude-phase value of surveying with the AD8302 chip is transferred to single-chip microcomputer, one-shot measurement is just finished.After having detected the 1st layer of impedance value, detect one deck down with identical method, up to all layers have been detected.The frequency that will have been surveyed the next one by single-chip microcomputer again after having detected sends to AD9850, continues to survey the impedance value of next frequency, till having surveyed all frequencies that will detect.
The power supply of this device is to be provided by USB by cellular phone power supplies.The USB power supply is the 5V dc source, and said chip needs the power supply of 3.3V power supply, powers so want a power-switching circuit that the 5V power supply is dropped to the 3.3V regulated power supply.This circuit can be used the LT1763CS8-3.3 chip, and the 5V power supply of USB interface is converted to 3.3V voltage stabilizing output, gives single-chip microcomputer and other chip power supplies.
Electrode uses general electrocardioelectrode.Because what need to measure is mammary gland tissue, and electrode need be close to skin surface and just can make to measure and reduce error.This device inserts electrode and measures on use medicated bra type latex material in the measurement design.Latex has the characteristic of absorption skin, and latex is close to skin surface during detection, and electrode also is close on the skin of mammary gland layer.
Fig. 6 is a mammary gland electrical impedance detector sketch map of the present invention.When actual measurement, earlier the mammary gland detection part is aimed at the good instrument of mammary gland band.Should steadily lie or be seated during measurement, the emulsion layer of mammary gland detection part internal layer is close to skin, electrode is adsorbed on the mammary gland.The mammary gland of opening then on the mobile phone detects software.When for the first time using mammary gland to detect software, need insert personal information earlier and generate the personal information storehouse, and directly enter account information bank at every turn when landing later on.Complete and can enter mammary gland after the personal information and detect the interface, enter the interface after software check that earlier USB connects situation.Can't carry out the mammary gland detection when makeing mistakes when occurring connecting, need check again whether USB plug connects.USB connects back click beginning test button and begins to measure the mammary gland electrical impedance.When measuring, should keep motionless and breathe not too big.Though measuring speed is very fast, the measurement data amount is big to need a period of time, can influence measurement result when moving or breathing greatly.Can point out detection to finish when having detected mobile phone, and can on cell phone software, check result images.At this moment can take off instrument, also can disconnect connection to USB.
After adding personal information on the mammary gland detection software of mobile phone, the tomograph that receives is stored in the individual database by date, be generated as the IMR storehouse, conveniently check and manage the individual state of an illness.Mobile phone also have to add and the deleted data function, when the more Out of Memory of the data time spent that mobile phone stores, can be saved in the data of deleting behind PC or other storage facilities on the mobile phone to data.Equally can be being kept at other local data, be saved in again on the mobile phone with adding function and data are added to mammary gland detect on the software and check.And these data can become the data base of individual case, for the diagnosis and treatment information is provided.
Fig. 7 is the scm software flow chart.Receive single-chip microcomputer when mobile phone USB line, when beginning to power to single-chip microcomputer, single-chip microcomputer is started working, and waits the mobile phone control command behind each chip of initialization.Cell phone software can be checked the connection state of USB, can send to check order.After single-chip microcomputer receives this inspection order, return and receive order to cell phone software.Cell phone software just can begin to detect electrical impedance after receiving and receiving order.When single-chip microcomputer received the electrical impedance sense command of mobile phone transmission, the single-chip microcomputer output command was given AD9850, made the stable AC signal of output.Then, single-chip microcomputer sends order to analog switch, and an electrode of ground floor is linked to each other with this AC signal outfan, selects an adjacent electrode with one deck to link to each other with power supply ground again.At this moment two electrodes are given the mammary gland tissue input exchange signal, and remaining electrode obtains voltage signal.Single-chip microcomputer sends order again to analog switch, and the remaining electrode with one deck is linked to each other with the input of amplitude-phase measurement chip successively.When every next electrode linked to each other with amplitude-phase measurement chip input, amplitude-phase measurement chip changed into digital signal to voltage signal and re-sends to the single-chip microcomputer input.After the single-chip microcomputer input receives data and data is stored into internal memory, can send order again to analog switch, analog switch is linked to each other next electrode and amplitude-phase measurement chip, detect the voltage signal of next electrode, surveyed with the voltage signal of the remaining electrode of one deck up to handle.After intact with the electrode voltage signal detection of one deck, single-chip microcomputer sends order to analog switch, an electrode of one deck is linked to each other with the AC signal outfan, select a adjacent electrode to link to each other again, with the voltage signal of identical method detection with one deck remaining electrode with power supply ground with one deck.Use the same method the voltage signal of all layers has been detected, single-chip microcomputer enters in the data processor, and detected voltage signal is changed into picture signal.Behind image reconstruction, single-chip microcomputer sends to mobile phone to picture signal, and finishes software.
Fig. 8 is the cell phone software block diagram.Cell phone software by personal information, detect electrical impedance and check that the image function interface forms.When using this cell phone software for the first time, need fill in personal information and make the personal information storehouse, so that search and manage individual testing result image.Enter detection electrical impedance interface and need to click earlier inspection USB connection state button inspection USB connection state.After inspection is errorless, can click the electrical impedance test button and send order to single-chip microcomputer, make single-chip microcomputer begin to detect electrical impedance.When detection was finished, mobile phone prompting checked successfully, and can enter and check that graphic interface checks the result.The mammary gland of mobile phone detects checking of software and checks result and interpolation or delete function in the data.Check and to check by date among the result that all are kept at the result images in the cell phone software catalogue.Add or delete function for browsing mobile phone EMS memory, and can in other catalogues of mobile phone EMS memory, add relevant result images data, also can from mobile phone EMS memory, delete the result images data under the software catalog.Interpolation or delete function are used for when low memory, the result images data are moved on other storage facilities store, and discharge mobile phone EMS memory.

Claims (4)

1. based on the breast electrical impedance fault imager of cell phone platform, it is characterized in that: described imager comprises mammary gland detection part, impedance detection circuitry, contains the hands machine of data result demonstration and analysis software; Described mammary gland detection part is " medicated bra shape ", and arranges the triple electrode group according to udder texture, is respectively mammary areola region electrode layer, middle part electrode layer and edge electrode layer, every layer electrode uniform distribution; Described impedance detection circuitry comprises single-chip microcomputer, frequency generator, filter amplification circuit, analog switch and the amplitude-phase detection chip that contains electrical impedance detection and process software; Impedance detection circuitry is the center with described single-chip microcomputer, the outfan of single-chip microcomputer is connected with the input of frequency generator by control circuit, the frequency signal of frequency generator output generates ac current signal through after the filter amplification circuit, ac current signal is inputed to a pair of adjacent electrode in one deck electrode group by analog switch by single-chip microcomputer, and by an electrode in this counter electrode ac current signal is inputed to mammary gland tissue, and another electrode links to each other with power supply ground; Voltage signal by obtain mammary gland tissue with the remaining electrode in one deck electrode group is input to the amplitude-phase detection chip by the Single-chip Controlling analog switch with voltage signal again, after transforming signal is input to single-chip microcomputer; The a pair of adjacent electrode of following one deck of the selected electrode group of reuse analog switch comes the input AC current signal after single-chip microcomputer has detected one deck electrode group, detects the electrical impedance of this layer; Use the same method and detected each electrode layer; After having detected, single-chip microcomputer changes into picture signal to signal through image reconstruction algorithm; Described single-chip microcomputer carries out two-way communication by communication module and described mobile phone, picture signal is sent to mobile phone, and show on mobile phone; The frequency of described frequency generator output is 1kHz~100kHz.
2. according to the described breast electrical impedance fault imager of claim 1 based on cell phone platform, it is characterized in that: the mammary gland detection part of described de is divided into internal layer and skin, internal layer is a latex material, described electrode group is arranged on the internal layer, described skin is an overcoat, arranges electrode cable between internal layer and skin.
3. according to the described breast electrical impedance fault imager based on cell phone platform of claim 2, it is characterized in that: the electrode density of described mammary areola region electrode layer and edge electrode layer is greater than the electrode density of middle part electrode layer.
4. according to the described breast electrical impedance fault imager based on cell phone platform of claim 1, it is characterized in that: described communication module adopts USB2.0 or bluetooth.
CN201010203015XA 2010-06-10 2010-06-10 Breast electrical impedance fault imager based on mobile phone platform Expired - Fee Related CN101856227B (en)

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CN106236074A (en) * 2016-08-22 2016-12-21 合肥芯福传感器技术有限公司 Health supervision band on underwear and health supervision underwear
CN109745047A (en) * 2019-01-22 2019-05-14 北京航空航天大学 A kind of electric impedance imaging system based on pressure resistance type electrode
CN114967556A (en) * 2022-06-01 2022-08-30 江苏百宁盈创医疗科技有限公司 Control system and method of portable breast biopsy device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007585A1 (en) * 1999-07-21 2001-02-01 The Regents Of The University Of California Electrical impedance tomography to control electroporation
US20100030089A1 (en) * 2008-04-24 2010-02-04 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for monitoring and modifying a combination treatment

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007585A1 (en) * 1999-07-21 2001-02-01 The Regents Of The University Of California Electrical impedance tomography to control electroporation
US20100030089A1 (en) * 2008-04-24 2010-02-04 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for monitoring and modifying a combination treatment

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CN102764120A (en) * 2012-08-17 2012-11-07 思澜科技(成都)有限公司 Electrode cover for mammography
CN102973269A (en) * 2012-12-24 2013-03-20 重庆大学 Device and method for measuring crossed plane electrical impedance tomography
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CN103284720A (en) * 2013-06-25 2013-09-11 思澜科技(成都)有限公司 Electrode fixing and locating device for breast impedance imaging
CN103284720B (en) * 2013-06-25 2017-12-05 思澜科技(成都)有限公司 A kind of electrode stationary positioned device for Breast electrical impedance imaging
CN103340626A (en) * 2013-07-19 2013-10-09 东南大学 Device for evaluating human body four-limb edema based on biological impedance and use method thereof
CN103735264A (en) * 2013-11-25 2014-04-23 北京华健恒创技术有限公司 Whole-breast electric impedance examination electrode
CN103735264B (en) * 2013-11-25 2015-12-30 北京华健恒创技术有限公司 A kind of Whole-breast electric impedance examination electrode
CN105899131A (en) * 2013-12-04 2016-08-24 株式会社K海奥斯威尔 Electrical impedance tomography device
CN105395169A (en) * 2014-10-28 2016-03-16 北京至感传感器技术研究院有限公司 Electrode assembly used for connecting human body and detection bra including the same
CN105266765A (en) * 2014-11-10 2016-01-27 北京至感传感器技术研究院有限公司 Device for detecting physiological changes of breasts
CN105495712A (en) * 2015-02-09 2016-04-20 北京至感传感器技术研究院有限公司 Bra assembly
CN105495712B (en) * 2015-02-09 2017-08-01 北京至感传感器技术研究院有限公司 Brassiere component
CN105476081A (en) * 2015-02-12 2016-04-13 北京至感传感器技术研究院有限公司 Bra assembly
CN105747294B (en) * 2015-04-13 2017-06-06 北京至感传感器技术研究院有限公司 Chest pad, chest pad component and mammary tumor detection means
CN105747294A (en) * 2015-04-13 2016-07-13 北京至感传感器技术研究院有限公司 Breast pad, breast pad assembly, and mammary tumor detection device
CN105212927A (en) * 2015-07-23 2016-01-06 杭州电子科技大学 For the Intelligent corsage of the early stage risk supervision assessment of breast carcinoma
CN105446362A (en) * 2015-12-07 2016-03-30 陆宁远 Posture detection adjusting device and method based on assistance of computer science
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