CN102068325A - Compound anti-blocking herniorrhaphy patch and preparation method thereof - Google Patents
Compound anti-blocking herniorrhaphy patch and preparation method thereof Download PDFInfo
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- CN102068325A CN102068325A CN201010600774XA CN201010600774A CN102068325A CN 102068325 A CN102068325 A CN 102068325A CN 201010600774X A CN201010600774X A CN 201010600774XA CN 201010600774 A CN201010600774 A CN 201010600774A CN 102068325 A CN102068325 A CN 102068325A
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- polypropylene
- sticking patch
- expanded polytetrafluoroethylsealing
- hernia
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Abstract
The invention relates a compound anti-blocking herniorrhaphy patch and a preparation method thereof, clinically belonging to herniorrhaphy implant medical appliances for abdominal wall defects and preparation methods thereof. The compound anti-blocking herniorrhaphy patch comprises a polypropylene patch and a puffed polytetrafluoroethylene anti-blocking patch, wherein the polypropylene patch and the puffed polytetrafluoroethylene anti-blocking patch are sewn into a whole by using puffed polytetrafluoroethylene. The preparation method provided by the invention comprises the following steps: (1) cutting a polypropylene reticular braided fabric in an ultrasonic or hot melting mode, or directly cutting the polypropylene reticular braided fabric into a polypropylene patch in a predetermined shape by using laser light; (2) cutting a puffed polytetrafluoroethylene anti-blocking film in an ultrasonic mode, or directly cutting the puffed polytetrafluoroethylene anti-blocking film into a puffed polytetrafluoroethylene anti-blocking patch in a predetermined shape by using laser light; and (3) sewing the cut polypropylene patch and puffed polytetrafluoroethylene anti-blocking patch into a whole by using the puffed polytetrafluoroethylene, thereby obtaining the compound anti-blocking herniorrhaphy patch.
Description
Technical field
What the present invention relates to is hernia patch of a kind of compound anti and preparation method thereof, belongs to hernia repair implant class medical apparatus and instruments of abdominal-wall defect and preparation method thereof clinically.
Background technology
Hernia is that fracture or reduction appear in the stomach wall that supports internal organs at certain position, makes that the interior internal organs of abdomen are outstanding to body surface by this fracture or weakened location, forms local lump.The method of the repairing hernia that adopts clinically is the position upper shed that takes place in hernia earlier at present, the internal organs of clamp-oning in this position are pushed back in the abdominal cavity, again will be by biocompatible materials: how the netted fabrics made from polypropylene repair that apparatuses (polypropylene sticking patch) place described opening and with it by sewing up or other mode fix in position, close this opening then.The advantage of this method is if operate suitably, and then near the distortion of bearing of the tissue the opening is few, and the corresponding tension force of receiving is also few, so be called " tension-free hernioplasty ".
(Polypropylene Mesh.Marlex, PP): formed by the polypropylene fibre braiding, be network structure, be the patching material of the abdominal-wall defect of present first-selection to the polypropylene sticking patch.In the period of 1958 to 1963, Usher writes articles the new material of having introduced a kind of Marlex50 of being called for many times, this material is compared with the metal or the nonmetallic materials of other any kinds same period, confirm all that through zoopery and clinical research it has following obvious advantage: (1) is more soft, and more tolerance is crooked and folding; (2) size is cut out with the need; (3) stimulate the proliferation of fibrous tissue effect more obvious, mesh aperture is big, is more conducive to fibrous tissue growth and passes, and is easily soaked into by connective tissue, can in early days and organize chimeric; (4) foreign body reaction is slight, and the patient does not have obvious foreign body and sense of discomfort, has very low relapse rate and complication rate.(5) more tolerance is infected, even granulation tissue still can be bred in the mesh of sticking patch in the pyogenic infection wound, does not cause that corrosion of net sheet or sinus tract form; (6) higher tensile strength is arranged; (7) be not subjected to the influence of water and most of chemical substances; (8) high temperature resistant, but scalding; (9) price is relatively cheap.
In in the past 50 years, polypropylene mesh has produced tremendous influence to surgical field, life is continued countless patients because it has been arranged, and many surgery knotty problems solve because of its application, and it has been proved to be most popular implant in the current surgery implantation field.
However, polypropylene net also exists some problems in application: at first, when being used for stomach wall holostrome defect repairing, sticking patch will be isolated with viscera tissue, if it directly contacts with internal organs and can cause more serious abdominal adhesions, digestive tract blocks, even may corrode intestinal wall, cause intestinal fistula, cause patient's misery even need second operation.
Adhesion is to cause the main cause of post-operative complication such as chronic pelvic pain, small intestinal obstruction etc. in the operation that relates to peritoneum, is the result of peritoneal injury and inflammation.At the impaired position of peritoneum, thereby the permeability of blood vessel increases the infiltration of formation inflammatory, and forms fibrin matrix in the part.These fibrin matrix form the fibrin bundle between adjacent tissue.In case fibroblast slips into the fibrin bundle and causes collagen deposition, just formed clinical visible adhesion.Referring to " subfamily that merits attention-abdominal cavity surgery progress ", bang unit etc., Chinese obstetrics magazine, the 39th the 4th phase of volume of April in 2004,278-280 page or leaf.
Expanded polytetrafluoroethylsealing anti sticking patch (Expanded Polytetrafluoroethylenepatch, e-PTFE): this sticking patch is difficult for when contacting with abdominal viscera forming adhesion than no tension force polypropylene sticking patch softness, and caused inflammatory reaction is also the lightest; But expanded polytetrafluoroethylsealing does not have support force, the easier secondary recurrence of stomach wall damaged part.Expanded polytetrafluoroethylsealing anti sticking patch allows antibacterial to pass through, and phagocyte can not can not be grown into by, tissue, so it can not tolerate and infect and pollute, the wound that can not be used to pollute will take out in case infect sticking patch, otherwise wound is difficult to heal.Expanded polytetrafluoroethylsealing anti sticking patch is used for Treatment of Recurrent Inguinal Hernia at present more; Because of directly contacting with internal organs, it causes adhesion hardly, so also incisional hernia that is used for more; Be used for the damaged little young inguinal hernia patient of hernia ring, can avoid some complication such as the adhesion of postoperative spermatic cord, painful ejaculation discomfort.
Summary of the invention
The present invention seeks at above-mentioned weak point, hernia patch of a kind of compound anti and preparation method thereof is provided, adopt one deck polypropylene sticking patch and one deck expanded polytetrafluoroethylsealing anti patching material to constitute, characteristics are to have taken into account the advantage that the polypropylene sticking patch does not have tension force and expanded polytetrafluoroethylsealing anti patching material anti, promptly not having tension force polypropylene net tissue grows into, implant the back firmly in the stomach wall growth, and the expanded polytetrafluoroethylsealing material can put people's intraperitoneal and contact with internal organs, and anti effect is preferably arranged.
Hernia patch of the compound anti of the present invention and preparation method thereof is to take following technical scheme to realize:
The hernia patch of compound anti comprises polypropylene sticking patch and expanded polytetrafluoroethylsealing anti sticking patch, and described polypropylene sticking patch and expanded polytetrafluoroethylsealing anti sticking patch adopt the expanded polytetrafluoroethylsealing suturing with thread management to be integral.
Described polypropylene sticking patch adopts no tension force polypropylene sticking patch, is netted fabric (commercially available).
Described expanded polytetrafluoroethylsealing anti sticking patch is membrane structure (commercially available).
Described polypropylene patching material thickness is: 0.1mm～1mm, grammes per square metre is: every square metre of 12.5g～125g.
Described expanded polytetrafluoroethylsealing anti patching material thickness is: 0.05mm～0.5mm.
The hernia patch manufacture method of compound anti is:
1, the polypropylene mesh fabric is adopted by the reservation shape cutter and cut into the polypropylene sticking patch of reservation shape by ultrasound wave or hot melt, described hot melt instantaneous trip temperature is 120 ℃～150 ℃; Or adopt laser directly the polypropylene mesh fabric to be cut out, directly be cut into the polypropylene sticking patch of reservation shape;
2, adopt the reservation shape cutter to cut into the expanded polytetrafluoroethylsealing anti sticking patch of reservation shape by ultrasound wave the expanded polytetrafluoroethylsealing Antiadhesive film; Or adopt laser with the expanded polytetrafluoroethylsealing Antiadhesive film, directly be cut into the expanded polytetrafluoroethylsealing anti sticking patch of reservation shape;
3, polypropylene sticking patch and the expanded polytetrafluoroethylsealing anti sticking patch with above-mentioned well cutting adopts the expanded polytetrafluoroethylsealing suturing with thread management to be integral, and promptly makes the hernia patch of compound anti.
Described reservation shape cutter is circular, oval, rectangle or irregularly shaped.
Described polypropylene sticking patch reservation shape is circular, oval, rectangle or irregularly shaped.
Described expanded polytetrafluoroethylsealing anti sticking patch reservation shape is circular, oval, rectangle or irregularly shaped.
Hernia patch of the compound anti of the present invention and preparation method thereof is reasonable in design, simple in structure, and is easy to use.Adopt polypropylene sticking patch and expanded polytetrafluoroethylsealing anti patching material to constitute, characteristics are to have taken into account the advantage that the polypropylene sticking patch does not have tension force and expanded polytetrafluoroethylsealing anti sticking patch anti, promptly not having tension force polypropylene net tissue grows into, implant the back firmly in the stomach wall growth, and the expanded polytetrafluoroethylsealing material can put into intraperitoneal and contact with internal organs, and anti effect is preferably arranged.The hernia patch manufacture method of anti is simple, and the yield rate height is convenient to produce good product quality in batches.
Description of drawings
The invention will be further described below with reference to accompanying drawing:
Fig. 1 is the hernia patch sketch map of compound anti.
Fig. 2 is the left view of the hernia patch of compound anti.
The specific embodiment
With reference to accompanying drawing 1,2, the hernia patch of compound anti comprises polypropylene sticking patch 2 and expanded polytetrafluoroethylsealing anti sticking patch 1, and described polypropylene sticking patch 2 and expanded polytetrafluoroethylsealing anti sticking patch 2 adopt the expanded polytetrafluoroethylsealing suturing with thread management to be integral.
Described polypropylene sticking patch 2 adopts no tension force polypropylene sticking patch, is netted fabric (commercially available).
Described expanded polytetrafluoroethylsealing anti sticking patch 1 is membrane structure (commercially available).
Described polypropylene sticking patch 2 material thicknesses are: 0.1mm～1mm, grammes per square metre is: every square metre of 12.5g～125g.
Described expanded polytetrafluoroethylsealing anti sticking patch 1 material thickness is: 0.05mm～0.5mm.
The hernia patch manufacture method of compound anti is:
1, the polypropylene mesh fabric is adopted by the reservation shape cutter and cut into the polypropylene sticking patch 2 of reservation shape by ultrasound wave or hot melt, described hot melt instantaneous trip temperature is 120 ℃～150 ℃; Or adopt laser directly the polypropylene mesh fabric to be cut out, directly be cut into the polypropylene sticking patch 2 of reservation shape;
2, adopt the reservation shape cutter to cut into the expanded polytetrafluoroethylsealing anti sticking patch 1 of reservation shape by ultrasound wave the expanded polytetrafluoroethylsealing Antiadhesive film; Or adopt laser with the expanded polytetrafluoroethylsealing Antiadhesive film, directly be cut into the expanded polytetrafluoroethylsealing anti sticking patch 1 of reservation shape;
3, polypropylene sticking patch 2 and the expanded polytetrafluoroethylsealing anti sticking patch 1 with above-mentioned well cutting adopts the expanded polytetrafluoroethylsealing suturing with thread management to be integral, and promptly makes the hernia patch of compound anti.
Described reservation shape cutter is circular, oval, rectangle or irregularly shaped.
Described polypropylene sticking patch 2 reservation shapes are circular, oval, rectangle or irregularly shaped.
Described expanded polytetrafluoroethylsealing anti sticking patch 1 reservation shape is circular, oval, rectangle or irregularly shaped.
The present invention still has multiple specific embodiment.All employings are equal to replacement or equivalent transformation and all technical schemes of forming, all drop in the scope of protection of present invention.
Claims (9)
1. the hernia patch of a compound anti is characterized in that comprising polypropylene sticking patch and expanded polytetrafluoroethylsealing anti sticking patch, and described polypropylene sticking patch and expanded polytetrafluoroethylsealing anti sticking patch adopt the expanded polytetrafluoroethylsealing suturing with thread management to be integral.
2. the hernia patch of compound anti according to claim 1 is characterized in that described polypropylene sticking patch adopts no tension force polypropylene sticking patch, is netted fabric.
3. the hernia patch of compound anti according to claim 1 is characterized in that described expanded polytetrafluoroethylsealing anti sticking patch is a thin film.
4. the hernia patch of compound anti according to claim 1 is characterized in that described polypropylene sticking patch thickness is 0.1mm～1mm, and grammes per square metre is every square metre of 12.5g～125g.
5. the hernia patch of compound anti according to claim 1 is characterized in that described expanded polytetrafluoroethylsealing anti sticking patch thickness is 0.05mm～0.5mm.
6. the hernia patch manufacture method of the described compound anti of claim 1 is characterized in that:
(1) the polypropylene mesh fabric is adopted by the reservation shape cutter and cut into the polypropylene sticking patch of reservation shape by ultrasound wave or hot melt, described hot melt instantaneous trip temperature is 120 ℃～180 ℃; Or adopt laser directly the polypropylene mesh fabric to be cut out, directly be cut into the polypropylene sticking patch of reservation shape;
(2) adopt the reservation shape cutter to cut into the expanded polytetrafluoroethylsealing anti sticking patch of reservation shape by ultrasound wave the expanded polytetrafluoroethylsealing Antiadhesive film; Or adopt laser directly with the expanded polytetrafluoroethylsealing Antiadhesive film, directly be cut into the expanded polytetrafluoroethylsealing anti sticking patch of reservation shape;
(3) polypropylene sticking patch and the expanded polytetrafluoroethylsealing anti sticking patch with above-mentioned well cutting adopts the expanded polytetrafluoroethylsealing suturing with thread management to be integral, and promptly makes the hernia patch of compound anti.
7. the hernia patch manufacture method of anti according to claim 6 is characterized in that described reservation shape cutter is circular, oval, rectangle or irregularly shaped.
8. the hernia patch manufacture method of anti according to claim 6 is characterized in that described polypropylene sticking patch reservation shape is circular, oval, rectangle or irregularly shaped.
9. the hernia patch manufacture method of anti according to claim 6 is characterized in that described expanded polytetrafluoroethylsealing anti sticking patch reservation shape is circular, oval, rectangle or irregularly shaped.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010600774XA CN102068325A (en) | 2010-12-21 | 2010-12-21 | Compound anti-blocking herniorrhaphy patch and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010600774XA CN102068325A (en) | 2010-12-21 | 2010-12-21 | Compound anti-blocking herniorrhaphy patch and preparation method thereof |
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| CN102068325A true CN102068325A (en) | 2011-05-25 |
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| CN201010600774XA Pending CN102068325A (en) | 2010-12-21 | 2010-12-21 | Compound anti-blocking herniorrhaphy patch and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104706443A (en) * | 2015-03-19 | 2015-06-17 | 东华大学 | Hernia repair patch having rigidity gradient change and manufacturing method thereof |
| CN110946650A (en) * | 2019-10-16 | 2020-04-03 | 日照天一生物医疗科技有限公司 | Double-layer anti-adhesion bag-shaped hernia repair method and system |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6652595B1 (en) * | 1996-03-25 | 2003-11-25 | Davol Inc. | Method of repairing inguinal hernias |
| CN201119926Y (en) * | 2007-04-02 | 2008-09-24 | 李向毅 | Double-layer sticking patch for non-tension force hernia mending |
| CN201996690U (en) * | 2010-12-21 | 2011-10-05 | 常州市三联星海医疗器械制造有限公司 | Compound anti-adhesion hernia repair patch |
-
2010
- 2010-12-21 CN CN201010600774XA patent/CN102068325A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6652595B1 (en) * | 1996-03-25 | 2003-11-25 | Davol Inc. | Method of repairing inguinal hernias |
| CN201119926Y (en) * | 2007-04-02 | 2008-09-24 | 李向毅 | Double-layer sticking patch for non-tension force hernia mending |
| CN201996690U (en) * | 2010-12-21 | 2011-10-05 | 常州市三联星海医疗器械制造有限公司 | Compound anti-adhesion hernia repair patch |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104706443A (en) * | 2015-03-19 | 2015-06-17 | 东华大学 | Hernia repair patch having rigidity gradient change and manufacturing method thereof |
| CN104706443B (en) * | 2015-03-19 | 2016-08-17 | 东华大学 | A kind of hernia with rigidity gradient change repairs sticking patch and preparation method thereof |
| CN110946650A (en) * | 2019-10-16 | 2020-04-03 | 日照天一生物医疗科技有限公司 | Double-layer anti-adhesion bag-shaped hernia repair method and system |
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Application publication date: 20110525 |