CN102921094A - Endovascular dilation guide wire and preparation method thereof - Google Patents
Endovascular dilation guide wire and preparation method thereof Download PDFInfo
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- CN102921094A CN102921094A CN2012104078434A CN201210407843A CN102921094A CN 102921094 A CN102921094 A CN 102921094A CN 2012104078434 A CN2012104078434 A CN 2012104078434A CN 201210407843 A CN201210407843 A CN 201210407843A CN 102921094 A CN102921094 A CN 102921094A
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Abstract
The invention discloses an endovascular dilation guide wire and a preparation method thereof. By the endovascular dilation guide wire, narrow positions of blood vessels are pre-dilated, so that saccules of pre-installed stents pass through the narrow pathological change positions of the blood vessels conveniently. The endovascular dilation guide wire comprises a core wire, wherein the middle part of the core wire is a dilation part; and the outer diameter of the dilation part is greater than that of the core wire. The preparation method comprises the following steps of: 1, preparing a guide wire head; 2, preparing the core wire; and 3, assembling the guide wire head on the core wire to obtain the endovascular dilation guide wire. Compared with the prior art, the endovascular dilation guide wire has the advantage that the narrow sections of the blood vessels are pre-dilated by utilizing the part, of which the diameter is the maximum, of the dilation guide wire, so that inner cavities of the narrow sections are dilated, and the saccules can pass through the narrow sections conveniently.
Description
Technical field
The present invention relates to a kind of medical surgical instrument and preparation method thereof, seal wire of the pre-expansion narrow positions of particularly using during a kind of interventional therapy angiostenosis and preparation method thereof.
Background information
Coronary heart disease is a kind of common disease of serious harm human health, its Therapeutic Method generally adopts implant frame treatment angiostenosis clinically except traditional Drug therapy, can effectively expand narrow blood vessel by getting involved implant frame, recover normal blood circulation, guarantee blood supply.In the process of implementing operation, at first need the true chamber of seal wire intravasation, after this, will pre-install the sacculus of support along seal wire by the vascular lesion position, if the narrow severity of diseased region, sacculus possibly can't pass through narrow section, therefore, need to expand seal wire pre-expansion narrow positions with one first, pass through again sacculus, thereby carry out subsequent procedures, can improve success rate of operation like this.But also do not have a kind of expansion seal wire that can pre-expansion angiostenosis position in the prior art, cause the sacculus can't be by the narrow section of blood vessel.
Summary of the invention
The purpose of this invention is to provide a kind of intravascular dilation seal wire and preparation method thereof, the technical problem that solve is pre-expansion angiostenosis position, and the sacculus of convenient prepackage support is by the angiostenosis diseased region.
The present invention is by the following technical solutions: a kind of intravascular dilation seal wire, be provided with the core silk, and the mid portion of described core silk is the expansion position, the external diameter at expansion position is greater than the external diameter of core silk.
Core silk of the present invention adopts nitinol alloy wire, and length is 1500 ~ 1800mm.
Core filament length degree of the present invention is degree 1800mm.
Core silk distal end of the present invention is connected with conductive filament head.
The platinum wire that conductive filament head diameter of the present invention is 0.05 ~ 0.076mm, tungsten alloy filament, billon silk or stainless steel silk turn to coil spring shape, helical spring external diameter 0.30 ~ 0.44mm, pitch 0.06 ~ 0.08mm, long 7 ~ 50mm.
Core silk of the present invention consists of by three sections, and expansion position diameter is 0.35 ~ 0.737mm; The proximal part diameter is 0.25 ~ 0.635mm; Distal portions is the distal end taper changeover portion, long 90~140mm, and the proximal diameter of distal end taper changeover portion is 0.25 ~ 0.635mm, the distal end diameter is 0.03 ~ 0.08mm; Described expansion position diameter is that the partial-length of 0.35 ~ 0.737mm is 1 ~ 20mm, is respectively the tapering transition section of growing 10 ~ 30mm at the expansion far-end at position and near-end with core silk joining place.
Proximal part diameter of the present invention is 0.635mm, and the proximal diameter of distal end taper changeover portion is 0.635mm.
Core silk of the present invention consists of by three sections, and expansion position diameter is 0.35 ~ 0.737mm; The proximal part diameter is 0.46 ~ 0.56mm; Distal portions is the distal end taper changeover portion, long 90~140mm, and the proximal diameter of distal end taper changeover portion is 0.25 ~ 0.635mm, the distal end diameter is 0.03 ~ 0.08mm; Described expansion position diameter is that the partial-length of 0.35 ~ 0.737mm is 1260 ~ 1670mm, divides joining place to be respectively the tapering transition section of growing 10 ~ 30mm at the expansion far-end at position and near-end with the core silk.
Proximal part diameter of the present invention is 0.56mm, and the proximal diameter of distal end taper changeover portion is 0.635mm.
A kind of preparation method of intravascular dilation seal wire, may further comprise the steps: one, make conductive filament head, be platinum wire, tungsten alloy filament, billon silk or the stainless steel silk of 0.05 ~ 0.076mm with diameter, around causing coil spring shape, the coiling rotating speed is 30 rev/mins, the helical spring external diameter that coiling obtains is 0.30 ~ 0.44mm, and pitch is 0.06 ~ 0.08mm, long 7 ~ 50mm; Two, make the core silk, the grinding filament diameter is 0.35 ~ 0.737mm, and length is that the distal portions of the nitinol alloy wire of 1500 ~ 1800mm is the distal end taper changeover portion, and the proximal part diameter is 0.25 ~ 0.635mm, 2000 rev/mins of rotating speeds, and amount of feeding 3mm/s obtains the core silk; Described distal end taper transition section length is 90~140mm, and the distal end diameter is 0.03 ~ 0.08mm, and the diameter of close end is 0.25 ~ 0.635mm; Described proximal part diameter is 0.25 ~ 0.635mm, and length is 1280~1689mm, or the proximal part diameter is 0.46 ~ 0.56mm, and length is 20 ~ 40mm; The enlarged portion bit length of described centre is 1 ~ 20mm, or the enlarged portion bit length is 1260 ~ 1670mm, and the far-end at expansion position and near-end are respectively the tapering transition section of growing 10 ~ 30mm with core silk joining place; Three, assemble conductive filament head at the core silk, in conductive filament head, insert the rustless steel flat filament that the cross section is 0.025 * 0.15mm, conductive filament head is nested with distal end at the core silk, conductive filament head, rustless steel flat filament and core silk is welded to connect electric current 80~100A, pulsewidth 4.0~6.0ms, frequency, 6~8Hz, weld interval 1~3s, the helical spring distal end of conductive filament head is worn into hemispherical shape, obtains the intravascular dilation seal wire.
The present invention compared with prior art utilizes the maximum position of expansion seal wire diameter pre-expansion angiostenosis section, makes the narrow section inner chamber become large, thereby makes things convenient for sacculus to pass through narrow section.
Description of drawings
Fig. 1 is the intravascular dilation guide wire sketch map of the embodiment of the invention 1.
Fig. 2 is the intravascular dilation guide wire sketch map of the embodiment of the invention 2.
Fig. 3 is the intravascular dilation seal wire pre-expansion angiostenosis section sketch map of the embodiment of the invention 1.
The specific embodiment
Below in conjunction with drawings and Examples the present invention is described in further details.In Fig. 1 to Fig. 3, each sequence number is expressed as: 1 is conductive filament head, and 2 are the expansion position, the maximum gauge position of intravascular dilation seal wire, and 3 is the core silk, and 4 is core silk proximal end, and 5 is the angiostenosis position.
Intravascular dilation seal wire of the present invention is provided with core silk 3, and one section of the mid portion of core silk 3 is expansion position 2, and the external diameter at expansion position 2 is greater than the external diameter of core silk 3, and core silk 3 distal ends are connected with conductive filament head 1.
As shown in Figure 1, core silk 3 is thread, and free state is linearity, and its distal end is connected with conductive filament head 1.Core silk 3 adopts nitinol alloy wire, and length is 1500 ~ 1800mm, and the best is length 1800mm.Core silk 3 consists of by three sections, and one section mid portion is expansion position 2 near the close distal end, and the diameter at expansion position 2 is 0.35 ~ 0.737mm, and one section diameter of proximal part is 0.25 ~ 0.635mm, and optimum diameter is 0.635mm.One section of core silk 3 distal portions is the distal end taper changeover portion, distal end taper transition segment length 90~140mm, the proximal diameter of distal end taper changeover portion is 0.25 ~ 0.635mm, optimum diameter is 0.635mm, the diameter of distal end is 0.03 ~ 0.08mm, is used for connecting conductive filament head 1.
It is platinum wire, tungsten alloy filament, billon silk or the stainless steel silk of 0.05 ~ 0.076mm that conductive filament head 1 adopts diameter, turns to coil spring shape, helical spring external diameter 0.30 ~ 0.44mm, pitch 0.06 ~ 0.08mm, long 7 ~ 50mm.Helical spring distal end is hemispherical shape.
As shown in Figure 2, core silk 3 is thread, and free state is linearity, and its distal end is connected with conductive filament head 1.Core silk 3 adopts nitinol alloy wire, and length is 1500 ~ 1800mm, and the best is length 1800mm.Core silk 3 consists of by three sections, and mid portion is expansion position 2, and the diameter at expansion position 2 is 0.35 ~ 0.737mm, and one section diameter of proximal part is 0.46 ~ 0.56mm, and optimum diameter is 0.56mm.One section of core silk 3 distal portions is the distal end taper changeover portion, distal end taper transition segment length 90~140mm, the proximal diameter of distal end taper changeover portion is 0.25 ~ 0.635mm, optimum diameter is 0.635mm, the distal end diameter is 0.03 ~ 0.08mm, is used for connecting conductive filament head 1.
It is platinum wire, tungsten alloy filament, billon silk or the stainless steel silk of 0.05 ~ 0.076mm that conductive filament head 1 adopts diameter, turns to coil spring shape, helical spring external diameter 0.30 ~ 0.44mm, pitch 0.06 ~ 0.08mm, long 7 ~ 50mm.Helical spring distal end is hemispherical shape.
The preparation method of intravascular dilation seal wire of the present invention may further comprise the steps:
One, makes conductive filament head 1
Adopting diameter is platinum wire, tungsten alloy filament, billon silk or the stainless steel silk of 0.05 ~ 0.076mm, at U.S. Roth Greaves﹠amp; Around causing coil spring shape, the coiling parameter is: rotating speed is 30 rev/mins on the L80 type precision spring curling machine that Associates.Inc company produces, and the helical spring external diameter that coiling obtains is 0.30 ~ 0.44mm, and pitch is 0.06 ~ 0.08mm, long 7 ~ 50mm.
Two, make core silk 3
With nitinol alloy wire, filament diameter is 0.35 ~ 0.737mm, and length is 1500 ~ 1800mm, and the best is diameter 0.737mm, length 1800mm.The distal portions of grinding nitinol alloy wire is the distal end taper changeover portion, and the proximal part diameter is 0.25 ~ 0.635mm, and the best is diameter 0.635mm, or diameter is 0.46 ~ 0.56mm, and the best is diameter 0.56mm.By behind the length blanking nitinol alloy wire, far-end and the near-end of nitinol alloy wire are ground to design size at the TG12X4 type cylindrical grinder that U.S. ROYAL MASTER GEINDERS.INC company makes, technological parameter is: 2000 rev/mins of rotating speeds, amount of feeding 3mm/s obtains core silk 3.The distal end taper transition section length of embodiment 1 is 90~140mm, and the distal end diameter is 0.03 ~ 0.08mm, and the diameter of close end is 0.25 ~ 0.635mm.The proximal part diameter is 0.25 ~ 0.635mm, and the best is diameter 0.635mm, and length is 1280~1689mm.Middle expansion position 2 length are 1 ~ 20mm, and the far-end at expansion position 2 and near-end and core silk 3 joining places are respectively the tapering transition section of long 10 ~ 30mm.The distal end taper transition section length of embodiment 2 is 90~140mm, and the distal end diameter is 0.03 ~ 0.08mm, and the diameter of close end is 0.25 ~ 0.635mm.The proximal part diameter is 0.46 ~ 0.56mm, and the best is diameter 0.56mm, and length is 20 ~ 40mm.Expansion position 2 length are 1260 ~ 1670mm, and the far-end at expansion position 2 and near-end and core silk 3 joining places are respectively the tapering transition section of long 10 ~ 30mm.
Three, at core silk 3 assembling conductive filament heads 1
The rustless steel flat filament that is 0.025 * 0.15mm in cross section of conductive filament head 1 interior insertion, tensile strength for increasing conductive filament head 1, conductive filament head 1 is nested with distal end at core silk 3, JHM-1GY-110H type laser-beam welding machine with Wuhan sky above Hubei and Hunan industrial lasers equipment company limited is made is welded to connect conductive filament head 1, rustless steel flat filament and core silk 3, and technological parameter is: electric current 80~100A, pulsewidth 4.0~6.0ms, frequency, 6~8HZ, weld interval 1~3s.Conductive filament head 1 helical spring distal end is worn into hemispherical shape.Obtain the intravascular dilation seal wire.
Embodiment 1, and core silk 3 length are 1800mm.The diameter at expansion position 2 is 0.737mm, and length is 20mm, and the far-end at expansion position 2 and near-end and core silk 3 joining places are respectively the tapering transition section of long 30mm.One section diameter of core silk 3 proximal parts is 0.635mm.Core silk 3 distal end taper transition segment length 140mm, the proximal diameter of distal end taper changeover portion is 0.635mm, the distal end diameter is 0.08mm.It is the stainless steel silk of 0.076mm that conductive filament head 1 adopts diameter, turns to coil spring shape, helical spring external diameter 0.44mm, pitch 0.08mm, long 50mm.
The intravascular dilation seal wire of embodiment 1 is used for animal experiment, selects one of 20 kilograms of tests of body weight beasle dog, in this dog body obvious coronary stenosis is arranged, thrombolysis in myocardial infarction treatment TIMI flow grading I level.Puncture through femoral artery, after under angiography, confirming the coronary stenosis position, under X ray monitors, the intravascular dilation seal wire is delivered to the narrow positions of vascular lesion through femoral artery, continuation pushes to expansion position from the intravascular dilation seal wire a to distant place is the narrow positions by arteria coronaria fully, can withdraw from the intravascular dilation seal wire, after withdrawing from the intravascular dilation seal wire, the sacculus of prepackage support can be smoothly by narrow positions and be delivered to its far-end, the proof expansion is effectively carried out follow-up coronary stent implant surgery by common percutaneous transluminal coronary stent implantation again.
With intravascular dilation seal wire of the present invention, can be used for pre-expansion angiostenosis position, the sacculus of convenient prepackage support is by the angiostenosis diseased region.
Claims (10)
1. an intravascular dilation seal wire is provided with core silk (3), it is characterized in that: the mid portion of described core silk (3) is expansion position (2), and the external diameter at expansion position (2) is greater than the external diameter of core silk (3).
2. intravascular dilation seal wire according to claim 1 is characterized in that: described core silk (3) adopts nitinol alloy wire, and length is 1500 ~ 1800mm.
3. intravascular dilation seal wire according to claim 2 is characterized in that: described core silk (3) length is degree 1800mm.
4. intravascular dilation seal wire according to claim 3, it is characterized in that: described core silk (3) distal end is connected with conductive filament head (1).
5. intravascular dilation seal wire according to claim 4, it is characterized in that: described conductive filament head (1) is that platinum wire, tungsten alloy filament, billon silk or the stainless steel silk of 0.05 ~ 0.076mm turns to coil spring shape with diameter, helical spring external diameter 0.30 ~ 0.44mm, pitch 0.06 ~ 0.08mm, long 7 ~ 50mm.
6. each described intravascular dilation seal wire in 5 according to claim 1, it is characterized in that: described core silk (3) consists of by three sections, and expansion position (2) diameter is 0.35 ~ 0.737mm; The proximal part diameter is 0.25 ~ 0.635mm; Distal portions is the distal end taper changeover portion, long 90~140mm, and the proximal diameter of distal end taper changeover portion is 0.25 ~ 0.635mm, the distal end diameter is 0.03 ~ 0.08mm; Described expansion position (2) diameter is that the partial-length of 0.35 ~ 0.737mm is 1 ~ 20mm, and far-end and near-end and core silk (3) joining place at expansion position (2) are respectively the tapering transition section of growing 10 ~ 30mm.
7. intravascular dilation seal wire according to claim 6, it is characterized in that: described proximal part diameter is 0.635mm, the proximal diameter of distal end taper changeover portion is 0.635mm.
8. each described intravascular dilation seal wire in 5 according to claim 1, it is characterized in that: described core silk (3) consists of by three sections, and expansion position (2) diameter is 0.35 ~ 0.737mm; The proximal part diameter is 0.46 ~ 0.56mm; Distal portions is the distal end taper changeover portion, long 90~140mm, and the proximal diameter of distal end taper changeover portion is 0.25 ~ 0.635mm, the distal end diameter is 0.03 ~ 0.08mm; Described expansion position (2) diameter is that the partial-length of 0.35 ~ 0.737mm is 1260 ~ 1670mm, and far-end and near-end and core silk (3) minute joining place at expansion position (2) are respectively the tapering transition section of growing 10 ~ 30mm.
9. intravascular dilation seal wire according to claim 8, it is characterized in that: described proximal part diameter is 0.56mm, the proximal diameter of distal end taper changeover portion is 0.635mm.
10. the preparation method of an intravascular dilation seal wire, may further comprise the steps: one, make conductive filament head, be platinum wire, tungsten alloy filament, billon silk or the stainless steel silk of 0.05 ~ 0.076mm with diameter, around causing coil spring shape, the coiling rotating speed is 30 rev/mins, the helical spring external diameter that coiling obtains is 0.30 ~ 0.44mm, and pitch is 0.06 ~ 0.08mm, long 7 ~ 50mm; Two, make the core silk, the grinding filament diameter is 0.35 ~ 0.737mm, and length is that the distal portions of the nitinol alloy wire of 1500 ~ 1800mm is the distal end taper changeover portion, and the proximal part diameter is 0.25 ~ 0.635mm, 2000 rev/mins of rotating speeds, and amount of feeding 3mm/s obtains the core silk; Described distal end taper transition section length is 90~140mm, and the distal end diameter is 0.03 ~ 0.08mm, and the diameter of close end is 0.25 ~ 0.635mm; Described proximal part diameter is 0.25 ~ 0.635mm, and length is 1280~1689mm, or the proximal part diameter is 0.46 ~ 0.56mm, and length is 20 ~ 40mm; The enlarged portion bit length of described centre is 1 ~ 20mm, or the enlarged portion bit length is 1260 ~ 1670mm, and the far-end at expansion position and near-end are respectively the tapering transition section of growing 10 ~ 30mm with core silk joining place; Three, assemble conductive filament head at the core silk, in conductive filament head, insert the rustless steel flat filament that the cross section is 0.025 * 0.15mm, conductive filament head is nested with distal end at the core silk, conductive filament head, rustless steel flat filament and core silk is welded to connect electric current 80~100A, pulsewidth 4.0~6.0ms, frequency, 6~8Hz, weld interval 1~3s, the helical spring distal end of conductive filament head is worn into hemispherical shape, obtains the intravascular dilation seal wire.
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CN107362437A (en) * | 2017-08-03 | 2017-11-21 | 湖南埃普特医疗器械有限公司 | A kind of predilation seal wire and preparation method thereof |
CN113769239A (en) * | 2021-10-12 | 2021-12-10 | 湖南省顺美医疗科技有限公司 | Method for manufacturing medical guide wire |
WO2023087459A1 (en) * | 2021-11-17 | 2023-05-25 | 上海腾复医疗科技有限公司 | Vascular recanalization device |
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