CN103110977A - Biodegradable copper-containing coating pure magnesium anastomosis nail and preparation method thereof - Google Patents
Biodegradable copper-containing coating pure magnesium anastomosis nail and preparation method thereof Download PDFInfo
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- CN103110977A CN103110977A CN2013100349681A CN201310034968A CN103110977A CN 103110977 A CN103110977 A CN 103110977A CN 2013100349681 A CN2013100349681 A CN 2013100349681A CN 201310034968 A CN201310034968 A CN 201310034968A CN 103110977 A CN103110977 A CN 103110977A
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Abstract
The invention provides a biodegradable copper-containing coating pure magnesium anastomosis nail and preparation method thereof. The pure magnesium anastomosis nail comprises the following material components in percentage by weight: 99.98-99.99 percent of pure magnesium, 0.002-0.004 percent of Zn, 0.003-0.06 percent of Ca, 0.002-0.004 percent of Fe and 0.003-0.006 percent of Mn. The biodegradable copper-containing coating pure magnesium anastomosis nail comprises an n-shaped pure magnesium anastomosis nail, wherein the nail body of the n-shaped pure magnesium anastomosis nail and a nail tip connecting part form a section of nail shoulder part with an angle of 20-40 degrees; and a copper ion coating is uniformly coated on the surface. The n-shaped pure magnesium anastomosis nail is formed by employing an extrusion processing mode and is suitable for human tissue and organ anastomosis; and because the nail body of the n-shaped pure magnesium anastomosis nail and the nail tip connecting part form the section of nail shoulder part with the angle of 20-40 degrees, when the anastomosis nail is used for anastomosis, the nail tip is pressed to the middle through the nail shoulder part with the angle of 20-40 degrees on the anastomosis nail, the meshed human tissues and organs are sewed together, the anastomosis nail is absorbed by the human body along with wound concrescence, and the wound surface concrescence and rehabilitation time is shortened.
Description
Technical field
The invention belongs to technical field of medical instruments, relate to the anastomosis staple that a kind of medical coinciding machine is used, specifically a kind of biodegradable contains the pure magnesium anastomosis staple of copper coating and preparation thereof.
Background technology
Along with the development of medical science technology, the doctor carries out tissue or organ is sewed up, and from original mode with the needlework manual suture, changes the mode of sewing up with medical anastomat and alloy anastomosis staple into.Use medical anastomat to sew up, convenient operation, the wound of coincide safely, bringing is very little, is accepted by vast surgical clinical doctor.But existing medical anastomat anastomosis staple used mostly adopts titanium alloy to make, because the titanium alloy corrosion resistance is relatively high, after sewing up, the titanium alloy anastomosis staple can be stayed in tissue or organ for a long time, might cause inflammation, not very comfortable sensation is always arranged for the people.So the scientific and technical personnel of medical science and biomaterial circle are according to the tissue characteristics of some metal materials, in succession develop the magnesium alloy materials that absorbs with degradable and make anastomosis staple, substitute the titanium alloy anastomosis staple to carry out the stitching of human tissue organ, allow be degraded when staying magnesium alloy anastomosis staple in human tissue organ along with the slowly healing of wound after sewing up or fragmentation is fallen.
But, reason due to magnesium alloy composition in the anastomosis staple of degradable absorption magnesium alloy materials, also there are some corresponding adverse effects, such as: the human tissue organ position of stitching directly contacts the anastomosis staple material, due to mishandling factor in the process of coincideing, be easy to cause wound infection and form secondary insult, give clinical verification and come into operation and cause some obstacles.
Summary of the invention
the purpose of this invention is to provide a kind of simple in structure, easy to use, be very suitable for the identical medical bio degradable of human tissue organ and contain the pure magnesium anastomosis staple of copper coating, it is by pure magnesium and Zn, Ca, Fe, the alloy material that Mn forms, be shaped by extruding or the mode of machining and make pure magnesium anastomosis staple with nail body and the nail tips of the pure magnesium anastomosis staple of nail shoulders connection " ㄇ " shape at 20～40 degree angles, and the copper ion coating of the surface uniform coating by pure magnesium anastomosis staple, play the anti-inflammation and sterilization effect to the identical wound surface of section of human tissue organ, and along with the healing of wound is absorbed by the body, the problems referred to above that existing anastomat exists with anastomosis staple have effectively been solved.
The invention provides a kind of biodegradable and contain the pure magnesium anastomosis staple of copper coating, the material composition of described pure magnesium anastomosis staple and proportioning be, pure magnesium 99.98～99.99%, Zn0.002～0.004%, Ca0.003～0.006%, Fe0.002～0.004%, Mn0.003～0.006%.
Biodegradable provided by the present invention contains the pure magnesium anastomosis staple of copper coating, and it comprises a pure magnesium anastomosis staple of " ㄇ " shape, and the nail body of the pure magnesium anastomosis staple of described " ㄇ " shape and nail tip connecting portion are shaped one section and become the nail shoulders at 20～40 degree angles,
Biodegradable of the present invention contains the pure magnesium anastomosis staple of copper coating, is further characterized in that, and the surface uniform coating layer of copper ionic coating of the pure magnesium anastomosis staple of described " ㄇ " shape, the thickness of coating is: 0.005～0.01mm.
Biodegradable of the present invention contains the preparation method of the pure magnesium anastomosis staple of copper coating, and the preparation method of this pure magnesium anastomosis staple comprises the following steps:
Step 1:
The material that is pure magnesium 99.98～99.99%, Zn0.002～0.004%, Ca0.003～0.006%, Fe0.002～0.004%, Mn0.003～0.006% with composition and proportioning pulls into the wire rod of 1mm * 1mm;
Step 2:
In pure magnesium wire surface spraying copper ion coating, the thickness of coating is: 0.005～0.01mm;
Step 3:
Entire length blanking by the pure magnesium anastomosis staple of " ㄇ " shape becomes section;
Step 4:
With the bending extruder with the be shaped pure magnesium anastomosis staple of " ㄇ " shape of the nail shoulder that to have nail body, nail tip and 20～40 degree angles of fashion of extrusion.
biodegradable of the present invention contains the pure magnesium anastomosis staple of copper coating, by pure magnesium and Zn, Ca, Fe, the alloy material that Mn forms pulls into wire rod, the mode of employing extrusion process is shaped and makes pure magnesium anastomosis staple with 20～40 nail body and the nail tips of spending the pure magnesium anastomosis staple of nail shoulders connection " ㄇ " shape at angle, being very suitable for human tissue organ coincide, because being shaped one section, the nail body of the pure magnesium anastomosis staple of " ㄇ " shape and nail tip connecting portion become the nail shoulders at 20～40 degree angles, when using anastomat to coincide, the angle is spent in meeting by anastomosis staple 20～40 nail shoulder presses to middle the pressure with nail tip, the human tissue organ of coincideing is stitched together.And the layer of copper ionic coating of the surface uniform coating by pure magnesium anastomosis staple, the identical wound surface of human tissue organ is played the anti-inflammation and sterilization effect, make identical human tissue organ not infected, and along with the healing of wound is absorbed by the body, be conducive to shorten the time of healing and the rehabilitation of wound surface.
Description of drawings
Fig. 1 is that biodegradable of the present invention contains the pure magnesium anastomosis staple of copper coating structural representation.
In figure, 1. pure magnesium anastomosis staple, 2. follow closely body, 3. nail tip, 4. nail shoulder.
The specific embodiment
The present invention is described in detail below in conjunction with the drawings and specific embodiments.
A kind of biodegradable contains the pure magnesium anastomosis staple of copper coating, and the material composition of this pure magnesium anastomosis staple and proportioning are: pure magnesium 99.98～99.99%, Zn0.002～0.004%, Ca0.003～0.006%, Fe0.002～0.004%, Mn0.003～0.006%.
Biodegradable of the present invention contains the pure magnesium anastomosis staple of copper coating, and as shown in Figure 1, it comprises a pure magnesium anastomosis staple 1 of " ㄇ " shape, and the nail body 2 of the pure magnesium anastomosis staple 1 of described " ㄇ " shape and nail tip 3 connecting portions are shaped one section and become the nail shoulders 4 at 20～40 degree angles; The surface uniform coating layer of copper ionic coating of the pure magnesium anastomosis staple 1 of " ㄇ " shape, the thickness of coating is: 0.005～0.01mm.
Biodegradable of the present invention contains the preparation method of the pure magnesium anastomosis staple of copper coating, comprises the following steps:
Step 1:
The material that is pure magnesium 99.98～99.99%, Zn0.002～0.004%, Ca0.003～0.006%, Fe0.002～0.004%, Mn0.003～0.006% with composition and proportioning pulls into the wire rod of 1mm * 1mm;
Step 2:
In pure magnesium wire surface spraying copper ion coating, the thickness of coating is: 0.005～0.01mm;
Step 3:
Entire length blanking by the pure magnesium anastomosis staple 1 of " ㄇ " shape becomes section;
Step 4:
With the bending extruder with the be shaped pure magnesium anastomosis staple 1 of " ㄇ " shape of the nail shoulder 4 that to have nail body 2, nail tip 3 and 20～40 degree angles of fashion of extrusion.
biodegradable of the present invention contains the pure magnesium anastomosis staple of copper coating, by pure magnesium and Zn, Ca, Fe, the alloy material that Mn forms pulls into wire rod, the mode of employing extruding or machining is shaped and makes pure magnesium anastomosis staple 1 with 20～40 nail bodies 2 of spending the nail shoulders 4 pure magnesium anastomosis staples of connection " ㄇ " shape at angle with nail tips 3, being very suitable for human tissue organ coincide, because being shaped one section, the nail body 2 of the pure magnesium anastomosis staple 1 of " ㄇ " shape and nail tip 3 connecting portions become the nail shoulders 4 at 20～40 degree angles, when using anastomat to coincide, the angle is spent in meeting by anastomosis staple 20～40 nail shoulder 4 presses to middle the pressure with nail tip 3, hooking is lived the human tissue organ on two sides, they are stitched together, and the copper ion coating of the surface uniform coating by pure magnesium anastomosis staple 1, the identical wound surface of human tissue organ is played the anti-inflammation and sterilization effect, make identical human tissue organ not infected, and along with the healing of wound is absorbed by the body, be conducive to shorten the time of healing and the rehabilitation of wound surface.
Above-mentioned embodiment is an example of the present invention, is not to limit working of an invention and interest field, and all equivalences of making according to the described content of the present patent application scope of patent protection change and modify, and all should be included in the present patent application the scope of the claims.
Claims (4)
1. a biodegradable contains the pure magnesium anastomosis staple of copper coating, it is characterized in that, the material composition of described pure magnesium anastomosis staple and proportioning be, pure magnesium 99.98～99.99%, Zn0.002～0.004%, Ca0.003～0.006%, Fe0.002～0.004%, Mn0.003～0.006%.
2. biodegradable according to claim 1 contains the pure magnesium anastomosis staple of copper coating, it comprises a pure magnesium anastomosis staple of " ㄇ " shape (1), it is characterized in that, the nail body (2) of described " ㄇ " the pure magnesium anastomosis staple of shape (1) and nail tip (3) connecting portion are shaped one section and become the nail shoulders (4) at 20～40 degree angles.
3. biodegradable according to claim 2 contains the pure magnesium anastomosis staple of copper coating, it is characterized in that, and the surface uniform coating layer of copper ionic coating of described " ㄇ " the pure magnesium anastomosis staple of shape (1), the thickness of coating is: 0.005～0.01mm.
4. according to claim 1 with 2 described biodegradables contain the preparation method of the pure magnesium anastomosis staple of copper coating, it is characterized in that, the preparation method of this pure magnesium anastomosis staple comprises the following steps:
Step 1:
The material that is pure magnesium 99.98～99.99%, Zn0.002～0.004%, Ca0.003～0.006%, Fe0.002～0.004%, Mn0.003～0.006% with composition and proportioning pulls into the wire rod of 1mm * 1mm;
Step 2:
In pure magnesium wire surface coating copper ion coating, the thickness of coating is: 0.005～0.01mm;
Step 3:
Entire length blanking by the pure magnesium anastomosis staple of " ㄇ " shape (1) becomes section;
Step 4:
With the bending extruder with the be shaped pure magnesium anastomosis staple of " ㄇ " shape (1) of the nail shoulder (4) that to have nail body (2), nail tip (3) and 20～40 degree angles of extrusion process mode.
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| CN201310034968.1A CN103110977B (en) | 2013-01-29 | 2013-01-29 | Biodegradable copper-containing coating pure magnesium anastomosis nail and preparation method thereof |
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| CN201310034968.1A CN103110977B (en) | 2013-01-29 | 2013-01-29 | Biodegradable copper-containing coating pure magnesium anastomosis nail and preparation method thereof |
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| CN103110977B CN103110977B (en) | 2014-08-20 |
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Cited By (3)
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| CN103330582A (en) * | 2013-06-06 | 2013-10-02 | 常熟市亨利医疗器械有限公司 | Absorbable suturing nail for foreskin incision stitching instrument |
| CN105078525A (en) * | 2015-08-31 | 2015-11-25 | 施爱德（厦门）医疗器材有限公司 | Surgical suturing nail with cutting function |
| CN107736906A (en) * | 2017-09-18 | 2018-02-27 | 天津理工大学 | A kind of Absorbale magnesium alloy skin closure nail and preparation method thereof |
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| CN1857744A (en) * | 2005-04-30 | 2006-11-08 | 中国科学院金属研究所 | Metal implant material with controllable corrosion and degradation and its application |
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| CN103330582A (en) * | 2013-06-06 | 2013-10-02 | 常熟市亨利医疗器械有限公司 | Absorbable suturing nail for foreskin incision stitching instrument |
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| CN107736906A (en) * | 2017-09-18 | 2018-02-27 | 天津理工大学 | A kind of Absorbale magnesium alloy skin closure nail and preparation method thereof |
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| Publication number | Publication date |
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| CN103110977B (en) | 2014-08-20 |
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Effective date of registration: 20211125 Address after: Ea415, yishili building, No. 9, headquarters Second Road, Songshanhu high tech Industrial Development Zone, Dongguan City, Guangdong Province Patentee after: DONGGUAN LIDE BIOLOGICAL MEDICAL Co.,Ltd. Address before: British Virgin Islands, the city of Victoria, the offshore registration center mailbox 957 Patentee before: EBOUR ORTHOPEDICS Ltd. |
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