CN103340713A - Transrectal hypothermia treatment device - Google Patents

Transrectal hypothermia treatment device Download PDF

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Publication number
CN103340713A
CN103340713A CN2013103164441A CN201310316444A CN103340713A CN 103340713 A CN103340713 A CN 103340713A CN 2013103164441 A CN2013103164441 A CN 2013103164441A CN 201310316444 A CN201310316444 A CN 201310316444A CN 103340713 A CN103340713 A CN 103340713A
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CN
China
Prior art keywords
water
water inlet
outlet pipe
inlet pipe
storage bag
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2013103164441A
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Chinese (zh)
Inventor
左泽兰
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Childrens Hospital of Chongqing Medical University
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Childrens Hospital of Chongqing Medical University
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Application filed by Childrens Hospital of Chongqing Medical University filed Critical Childrens Hospital of Chongqing Medical University
Priority to CN2013103164441A priority Critical patent/CN103340713A/en
Publication of CN103340713A publication Critical patent/CN103340713A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a transrectal hypothermia treatment device comprising a water inlet pipe, a water outlet pipe and an elastic water storage bag. The water outlet end of the water inlet pipe and the water inlet end of the water outlet pipe are arranged in the water storage bag, and the opening of the water storage bag is connected with the water inlet pipe and the water outlet pipe in a sealed mode. According to the transrectal hypothermia treatment device, the water storage bag is inserted into the rectum of a patient, the water storage bag can expand in an elastic mode, is well fixed in the rectum of the patient and is attached to the rectum wall, and the heat exchange effect is good. Cooling water enters or gets out of the water storage bag through the water inlet pipe and the water outlet pipe to lower the temperature of the patient, so that the whole body of the patient is in a hypothermia state, cellular energy metabolism is improved, generation of oxygen radicals is reduced, intracellular calcium overload is lightened, cell necrosis and apoptosis are reduced, intercellular signal transduction recovery is promoted, encephaledema is reduced, intracranial pressure is reduced, the disability rate and fatality rate of hypoxic-ischemic brain damage are remarkably reduced, and survival quality is improved. Besides, the transrectal hypothermia treatment device has the advantages of being simple in structure, low in cost, portable, convenient to use, easy to popularize and the like.

Description

Per rectum mild hypothermia therapy device
Technical field
The present invention relates to a kind of medical apparatus and instruments, particularly the therapeutic device of a kind of prevention and treatment ischemic hypoxia brain injury.
Background technology
Body temperature is called inferior low temperature for 35 ℃ at 28 ℃ –.The end of the eighties, discover the brain temperature descend 2~3 ℃ (inferior low temperature) ischemic brain injury is had protective effect, and do not have the various complication due to the profound hypothermia, make people begin research to mild hypothermia therapy.
Discover inferior low temperature can reduce CMRO2 and improve the cellular energy metabolism, reduce oxygen-derived free radicals generation, reduce intracellular calcium overload, increase the neuron ubiquitin synthetic, the recovery, the area that reduces cerebral infarction that reduce neuronal necrosis and apoptosis, the conduction of promotion intercellular signal, alleviate cerebral edema and reduce effects such as intracranial pressure.Research finds that also low temperature does not have influence to blood pressure, blood oxygen pressure, partial pressure of carbon dioxide, blood pH value and blood glucose, the ischemic hypoxia brain injury animal model is carried out the per rectum mild hypothermia therapy, the heart, lung, kidney, small intestinal are not seen pathologic lesion yet, illustrate that the inferior low temperature of per rectum does not increase the infringement of other histoorgans.
Therefore design a kind of per rectum mild hypothermia therapy device, significant to prevention and treatment ischemic hypoxia brain injury.
Summary of the invention
In view of this, the purpose of this invention is to provide a kind of per rectum mild hypothermia therapy device, it has characteristics such as simple in structure, easy to use, can effectively continue to reduce patient's body temperature, and reach inferior low temperature state, reduce fatality rate and the disability rate of ischemic hypoxia brain injury patients.
Per rectum mild hypothermia therapy device of the present invention comprises water inlet pipe, outlet pipe and rubber-like water reservoir, and the water side of water inlet pipe and the water inlet end of outlet pipe are arranged in the water reservoir, and the oral area of water reservoir and water inlet pipe and outlet pipe are tightly connected.
Further, the water inlet end of described water inlet pipe is connected with piercing needle.
Further, the outlet of described water inlet pipe is near the bottom of water reservoir, and the water inlet of described outlet pipe is near the oral area of water reservoir.
Further, the water inlet pipe pipeline section that is arranged in water reservoir is fixedlyed connected with the outlet pipe pipeline section and is integral.
Further, described water inlet pipe pipeline section and the outlet pipe pipeline section that is arranged in water reservoir links into an integrated entity by parcel overlay film on the outer surface.
Further, be provided with flow control valve and Murphy's burette on described water inlet pipe and the outlet pipe.
Further, described water inlet pipe and outlet pipe are plastic cement pipe or rubber tube.
Further, described water reservoir is rubber bag tank.
Further, the water side of described outlet pipe is connected with the water storage bag, and the bottom of described water storage bag is provided with cock of water drain.
Beneficial effect of the present invention: per rectum mild hypothermia therapy device of the present invention, water reservoir to be inserted in patient's the rectum, the water reservoir elastic expansion can well be fixed in patient's rectum and with rectal wall to be close to, and heat exchange effect is good; Cooling water is lowered the temperature to the patient by water inlet pipe and outlet pipe turnover water reservoir, patient's whole body is in continues inferior low temperature state, can improve the cellular energy metabolism, reduce the histoorgan basal metabolic rate, reduction is to the consumption of oxygen and energy, reduce the generation of oxygen-derived free radicals, alleviate intracellular calcium overload, reduce necrocytosis and apoptosis, promote the recovery of intercellular signal conduction, alleviate cerebral edema and reduce intracranial pressure etc., obviously reduce the fatality rate that disables of ischemic hypoxia brain injury patients, improve life quality; And that this device also has is simple in structure, low cost of manufacture, portable, easy to use, be easy to advantages such as popularization, can in medical institutions at different levels and pre hospital care, use.
Description of drawings
Below in conjunction with drawings and Examples the present invention is further described.
Fig. 1 is the structural representation of per rectum mild hypothermia therapy device of the present invention.
The specific embodiment
As shown in the figure 1, present embodiment per rectum mild hypothermia therapy device, comprise water inlet pipe 1, outlet pipe 2 and rubber-like water reservoir 3, the water inlet end of the water side of water inlet pipe 1 and outlet pipe 2 is arranged in the water reservoir 3, and the oral area of water reservoir 3 and water inlet pipe 1 and outlet pipe 2 are tightly connected.
During use, water reservoir 3 is inserted in patients' the rectum, and by water inlet pipe 1 cooling water is input in the water reservoir 3, water reservoir 3 elastic expansion under hydraulic pressure, can well be fixed in patient's rectum and with rectal wall and be close to, heat exchange effect is good; Cooling water continues cooling by water inlet pipe 1 and 3 couples of patients of outlet pipe 2 turnover water reservoirs, makes patient's whole body be in inferior low temperature state, can effectively prevent and treat the ischemic hypoxia brain injury.
As the improvement to this enforcement, the water inlet end of described water inlet pipe 1 is connected with piercing needle 4, can be connected the cooling water of packing in transfusion bag easily with transfusion bag by piercing needle 4, thereby when treatment, can as transfusion, cooling water be imported in the water reservoir 3, easy to operate; Certainly in different embodiments, described water inlet pipe 1 also can be connected by the joint of other form and the cooling water container of other form, also can realize purpose of the present invention.
As the improvement to this enforcement, the outlet 101 of described water inlet pipe 1 is near the bottom of water reservoir 3, the water inlet 201 of described outlet pipe 2 is near the oral area of water reservoir 3, and setting can make cooling water by the principle turnover water reservoir 3 of first in first out, cooling therapeutic better effects if like this.
As the improvement to this enforcement, the water inlet pipe pipeline section that is arranged in water reservoir 3 is fixedlyed connected with the outlet pipe pipeline section and is integral, arrange like this make water reservoir 3 can easier insertion patient rectum in.
As the improvement to this enforcement, described water inlet pipe pipeline section and the outlet pipe pipeline section that is arranged in water reservoir 3 links into an integrated entity by parcel overlay film 5 on the outer surface, the water inlet pipe pipeline section and the outlet pipe pipeline section that are arranged in water reservoir 3 like this are a pipe in appearance, rigidity is better, easier insertion patient rectum, and outward appearance is also more good-looking.Certainly the water inlet pipe pipeline section and the outlet pipe pipeline section that are arranged in water reservoir 3 in different embodiments also can connect into integral body by alternate manner, as passing through heat fused mode or bonding way etc.
As the improvement to this enforcement, be provided with flow control valve 6 and Murphy's burette 7 on described water inlet pipe 1 and the outlet pipe 2, this improvement can be observed the flow velocity of cooling water intuitively by Murphy's burette 7, can regulate the cooling water flow velocity easily by flow control valve 6, and then make cooling rate controlled, guarantee that patient's brain is in inferior low temperature state.
As the improvement to present embodiment, described water inlet pipe 1 and outlet pipe 2 are the plastic cement pipe, and the plastic cement pipe has certain intensity, can guarantee water reservoir 3 is inserted in patient's rectum smoothly, and plastic cement pipe manufacturer cost are lower; Certainly in different embodiments, described water inlet pipe 1 and outlet pipe 2 also can be rubber tube.
As the improvement to present embodiment, described water reservoir 3 is rubber bag tank, the rubber bag tank good springiness, but under hydraulic pressure rapid expanding, and rubber chemistry character is comparatively stable, nonpoisonous and tasteless, can not damage human body.
As the improvement to present embodiment, the water side of described outlet pipe 2 is connected with water storage bag 8, and the bottom of described water storage bag 8 is provided with cock of water drain 9; In therapeutic process, water storage bag 8 is used for collecting the cooling water of discharging, and when making treatment the cooling water container need not be set specially, can make treatment more convenient.
Explanation is at last, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although with reference to preferred embodiment the present invention is had been described in detail, those of ordinary skill in the art is to be understood that, can make amendment or be equal to replacement technical scheme of the present invention, and not breaking away from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.

Claims (9)

1. per rectum mild hypothermia therapy device, it is characterized in that: comprise water inlet pipe, outlet pipe and rubber-like water reservoir, the water side of water inlet pipe and the water inlet end of outlet pipe are arranged in the water reservoir, and the oral area of water reservoir and water inlet pipe and outlet pipe are tightly connected.
2. per rectum mild hypothermia therapy device according to claim 1, it is characterized in that: the water inlet end of described water inlet pipe is connected with piercing needle.
3. per rectum mild hypothermia therapy device according to claim 1 is characterized in that: the bottom of the close water reservoir of the outlet of described water inlet pipe, the oral area of the close water reservoir of the water inlet of described outlet pipe.
4. per rectum mild hypothermia therapy device according to claim 1 is characterized in that: the water inlet pipe pipeline section that is arranged in water reservoir is fixedlyed connected with the outlet pipe pipeline section and is integral.
5. per rectum mild hypothermia therapy device according to claim 4 is characterized in that: described water inlet pipe pipeline section and the outlet pipe pipeline section that is arranged in water reservoir links into an integrated entity by parcel overlay film on the outer surface.
6. per rectum mild hypothermia therapy device according to claim 1 is characterized in that: be provided with flow control valve and Murphy's burette on described water inlet pipe and the outlet pipe.
7. per rectum mild hypothermia therapy device according to claim 1, it is characterized in that: described water inlet pipe and outlet pipe are plastic cement pipe or rubber tube.
8. per rectum mild hypothermia therapy device according to claim 1, it is characterized in that: described water reservoir is rubber bag tank.
9. according to arbitrary described per rectum mild hypothermia therapy device among the claim 1-7, it is characterized in that: the water side of described outlet pipe is connected with the water storage bag, and the bottom of described water storage bag is provided with cock of water drain.
CN2013103164441A 2013-07-25 2013-07-25 Transrectal hypothermia treatment device Pending CN103340713A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2013103164441A CN103340713A (en) 2013-07-25 2013-07-25 Transrectal hypothermia treatment device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2013103164441A CN103340713A (en) 2013-07-25 2013-07-25 Transrectal hypothermia treatment device

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CN103340713A true CN103340713A (en) 2013-10-09

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111787890A (en) * 2017-12-19 2020-10-16 塞比卡有限公司 Low-temperature treatment device capable of preventing nerve injury
WO2022200550A1 (en) * 2021-03-25 2022-09-29 Chiesi Farmaceutici S.P.A. Combined treatment of brain injury

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110125234A1 (en) * 2009-02-26 2011-05-26 Advanced Cooling Therapy, Llc Devices and Methods For Controlling Patient Temperature
CN102309786A (en) * 2011-07-21 2012-01-11 珠海成富医疗器材有限公司 System for filling fluid into rectum and reducing temperature of human body
CN202314614U (en) * 2011-11-08 2012-07-11 王传荣 Traditional Chinese medicine retention clysis device
CN203043284U (en) * 2012-12-25 2013-07-10 天津市塑料研究所有限公司 Heat exchange saccule guide pipe for mild hypothermia therapy in vessel
CN203354749U (en) * 2013-07-25 2013-12-25 重庆医科大学附属儿童医院 Transrectal sub-low temperature treatment device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110125234A1 (en) * 2009-02-26 2011-05-26 Advanced Cooling Therapy, Llc Devices and Methods For Controlling Patient Temperature
CN102309786A (en) * 2011-07-21 2012-01-11 珠海成富医疗器材有限公司 System for filling fluid into rectum and reducing temperature of human body
CN202314614U (en) * 2011-11-08 2012-07-11 王传荣 Traditional Chinese medicine retention clysis device
CN203043284U (en) * 2012-12-25 2013-07-10 天津市塑料研究所有限公司 Heat exchange saccule guide pipe for mild hypothermia therapy in vessel
CN203354749U (en) * 2013-07-25 2013-12-25 重庆医科大学附属儿童医院 Transrectal sub-low temperature treatment device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111787890A (en) * 2017-12-19 2020-10-16 塞比卡有限公司 Low-temperature treatment device capable of preventing nerve injury
WO2022200550A1 (en) * 2021-03-25 2022-09-29 Chiesi Farmaceutici S.P.A. Combined treatment of brain injury

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Application publication date: 20131009