CN103623494A - Titanium alloy guide wire for surgical interventional therapy - Google Patents

Titanium alloy guide wire for surgical interventional therapy Download PDF

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Publication number
CN103623494A
CN103623494A CN201310682015.6A CN201310682015A CN103623494A CN 103623494 A CN103623494 A CN 103623494A CN 201310682015 A CN201310682015 A CN 201310682015A CN 103623494 A CN103623494 A CN 103623494A
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titanium alloy
seal wire
helical groove
single helical
pitch
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CN201310682015.6A
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CN103623494B (en
Inventor
余森
于振涛
袁思波
刘春潮
牛金龙
张亚峰
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Northwest Institute for Non Ferrous Metal Research
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Northwest Institute for Non Ferrous Metal Research
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09058Basic structures of guide wires
    • A61M2025/09066Basic structures of guide wires having a coil without a core possibly combined with a sheath
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/0915Guide wires having features for changing the stiffness

Abstract

The invention discloses a titanium alloy guide wire for interventional therapy. The titanium alloy guide wire comprises a titanium alloy small-diameter thin-wall tube and a noble metal end head which is distributed at the far end of the titanium alloy small-diameter thin-wall tube; the titanium alloy small-diameter thin-wall tube is divided into a guide wire far section, a guide wire middle section and a guide wire near section from far to near; a single spiral groove I is formed in the tube wall of the guide wire far section; a single spiral groove II is formed in the tube wall of the guide wire middle section; the single spiral slot I is an uniform-pitch spiral groove; the single spiral groove II is a variable-pitch spiral groove; the groove widths of the single spiral groove I and the single spiral groove II are same; the pitch of the single spiral groove II is gradually increased from far to near, and the pitch at the far end of the single spiral groove II is equal to that of the single spiral groove I; the groove depth of the single spiral groove I and the single spiral groove II is the same as the wall thickness of the titanium alloy small-diameter thin-wall tube. The titanium alloy guide wire disclosed by the invention is simple in structure, reasonable in design, simple and convenient to machine and manufacture, good in using effect, and capable of effectively solving the problems such as a complex machining process, high cost and poor adaptability of the existing titanium alloy guide wire.

Description

A kind of surgery interventional therapy titanium alloy seal wire
Technical field
The present invention relates to a kind of surgery intervention therapeutic apparatus that belongs to, especially relate to a kind of surgery interventional therapy titanium alloy seal wire.
Background technology
Interventional guide wire, also referred to as guide wire or guide wire, is one of main tool of percutaneous puncture intubate.Seal wire plays guiding, support and positioning action to conduit, helps conduit intravasation and other lacunas, and guide catheter arrives lesion smoothly, is the indispensable auxiliary products of many intervention equipment, and consumption is very large.The consumption of the 1 year seal wire in the whole world is about 6,400 ten thousand, and its market sales revenue is 700,000,000 dollars.1,500,000 of China's annual consumption of seal wire in recent years, market capacity is 2.7 hundred million RMB, accounts for 5% of world market share.Along with popularizing of China's interventional therapy and Intensive Care Therapy treatment technology, the seal wire use amount of China is by the speed increment with annual 20%.
Seal wire requires to have good handling, refers to patient and rotates the nearly section of seal wire (external metal push rod section), and its tip (far away section of seal wire) is with the ability of patient's rotation, twisting.Seal wire requires to have suitable compliance, is mainly reflected in following several respects: the first, seal wire is complied with blood vessel naturalness by the ability of pathological changes, enough propelling movement power; The second, seal wire passes through the ability of pathological changes and outstanding holding power outside patient's manipulator under push rod effect; Three, seal wire is as the conveying of PTCA sacculus and support, and it is at lesion vessels, particularly the degree of stability in complex lesions blood vessel.Structure and the material of these performances and seal wire are closely related.
Clinical conventional seal wire consists of inside and outside two parts now, and skin is that high-quality stainless steel silk is reeled and formed on spring lathe.Bright and clean, tough and tensile, the high resilience of steel wire requirement, evenly tight, the marshalling, loose close consistent of reeling.This spring should be able to tolerate bending repeatedly, unlikely fractureing under certain strength effect.The cavity of spring center is the inside of seal wire, is equipped with always and hard wire-core, and the front end of wire-core attenuates gradually.The tip of very very thin wire-core and spring end are welded together, then by wire-core tail end and the welding of spring tail end, and polish smooth, the simplest seal wire become.But its manufacturing process is complicated, and molding difficulty is high.
In addition, guidewire material requires to have good toughness, intensity, decay resistance and bio-compatible performance, and the main material of application has Stainless steel 316 L, Nitinol, cobalt-base alloys etc. at present.Wherein the performance of titanium alloy is far superior to rustless steel.The density little (4.51) of titanium or titanium alloy, tensile strength high (can reach 140 kilograms/square millimeter), its specific strength is the highest in all metal materials, and has excellent decay resistance and good bioaffinity, there is no cytotoxicity, is desirable medical apparatus and instruments material.
Summary of the invention
Technical problem to be solved by this invention is for above-mentioned deficiency of the prior art, a kind of surgery interventional therapy titanium alloy seal wire is provided, it is simple in structure, reasonable in design and processing and fabricating is easy, result of use is good, can effectively solve the problems such as the course of processing that existing titanium alloy seal wire exists is complicated, cost is high, bad adaptability.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of surgery interventional therapy titanium alloy seal wire, it is characterized in that: comprise titanium alloy fine-radial thin-wall pipes and the noble metal termination that is laid in titanium alloy fine-radial thin-wall pipes far-end, described titanium alloy fine-radial thin-wall pipes is divided into seal wire section far away, seal wire stage casing and the nearly section of seal wire three parts from far near, and described noble metal termination is to be the hemispherical ends of coaxial laying with titanium alloy fine-radial thin-wall pipes; On the tube wall of described seal wire section far away, have single helical groove one, on the tube wall in described seal wire stage casing, have single helical groove two, described single helical groove one is uniform pitch helicla flute, described single helical groove two is variable-pitch auger groove, the groove width of described single helical groove one and single helical groove two is all identical, and the pitch of described single helical groove two increases gradually from far near and the pitch of its far-end equates with the pitch of single helical groove one; The groove depth of described single helical groove one and single helical groove two is all identical with the wall thickness of titanium alloy fine-radial thin-wall pipes.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: the external diameter of described titanium alloy fine-radial thin-wall pipes is that Φ 2mm~Φ 0.5mm and its wall thickness are 0.4mm~0.1mm.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: the material of described titanium alloy fine-radial thin-wall pipes is pure titanium, Ti6Al4V titanium alloy, Ti6Al7Nb titanium alloy or TiNi titanium alloy.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: the diameter of described noble metal termination is identical with the external diameter of titanium alloy fine-radial thin-wall pipes.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: the material of described noble metal termination is platinum, gold or platinumiridio.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: the groove width of described single helical groove one and single helical groove two is 0.01mm~0.2mm.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: the pitch of described single helical groove one is 0.2mm~0.5mm.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: the pitch of described single helical groove two is that gradient pitch and its increase progressively with 0.05mm~0.3mm from far near.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: the length L 1=5mm~50mm of described seal wire section far away, the length L 2=10mm~100mm in described seal wire stage casing, the length L 3=10mm~200mm of the nearly section of described seal wire.
Above-mentioned a kind of surgery interventional therapy titanium alloy seal wire, is characterized in that: described single helical groove one and single helical groove two are the helicla flute that adopts the molding of laser engraving machine engraving.
The present invention compared with prior art has the following advantages:
1, simple in structure and processing and fabricating is easy, on single titanium alloy fine-radial thin-wall pipes tube wall, laser engraving processes helicla flute, with low cost, and seal wire property regulation is interval large, is easy to large-scale production.
2, reasonable in design, the pitch of seal wire section far away is less and be consistent, for interventional guide wire provides good compliance.Seal wire stage casing is designed to spiral involute structure, can for seal wire provide good pliability transition and and outstanding handling and support force, make interventional guide wire there is good compliance, handling and enough support forces simultaneously.
3, by regulating external diameter, wall thickness and the single helical groove one of thin footpath thin-wall titanium alloy tubing and the groove width of single helical groove two and pitch energy easy to the compliance of seal wire and handling adjustment, strong adaptability.
4, result of use is good and practical value is high, it is simple and practical, the course of processing is simple, dimensional accuracy is high, large and clinical applied widely between performance control region, be easy to realize mass production, and can be easy the compliance of seal wire and the performance such as handling be adjusted by regulating external diameter, wall thickness and the single helical groove one of thin footpath thin-wall titanium alloy tubing and the groove width of single helical groove two and pitch, to meet clinical different parts, use needs, can effectively solve defect and the deficiencies such as the course of processing that existing titanium alloy seal wire exists is complicated, cost is high, bad adaptability.
In sum, the present invention is simple in structure, reasonable in design and processing and fabricating is easy, result of use is good, can effectively solve the problems such as the course of processing that existing titanium alloy seal wire exists is complicated, cost is high, bad adaptability.
Below by drawings and Examples, technical scheme of the present invention is described in further detail.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention.
Description of reference numerals:
1-titanium alloy fine-radial thin-wall pipes; 2-noble metal termination; 3-single helical groove one;
4-single helical groove two.
The specific embodiment
Embodiment 1
A kind of surgery interventional therapy titanium alloy seal wire as shown in Figure 1, comprise titanium alloy fine-radial thin-wall pipes 1 and the noble metal termination 2 that is laid in titanium alloy fine-radial thin-wall pipes 1 far-end, described titanium alloy fine-radial thin-wall pipes 1 is divided into seal wire section far away, seal wire stage casing and the nearly section of seal wire three parts from far near, and described noble metal termination 2 is to be the hemispherical ends of coaxial laying with titanium alloy fine-radial thin-wall pipes 1.On the tube wall of described seal wire section far away, have single helical groove 1, on the tube wall in described seal wire stage casing, have single helical groove 24, described single helical groove 1 is uniform pitch helicla flute, described single helical groove 24 is variable-pitch auger groove, the groove width of described single helical groove 1 and single helical groove 24 is all identical, and the pitch of described single helical groove 24 increases gradually from far near and the pitch of its far-end equates with the pitch of single helical groove 1.The groove depth of described single helical groove 1 and single helical groove 24 is all identical with the wall thickness of titanium alloy fine-radial thin-wall pipes 1.
Actually add man-hour, described single helical groove 1 and single helical groove 24 are connected, and specifically the near-end of single helical groove 1 is connected with the far-end of single helical groove 24.
In the present embodiment, described single helical groove 1 and single helical groove 24 are the helicla flute that adopts the molding of laser engraving machine engraving, thereby machine-shaping is very easy.And the groove depth of single helical groove 1 and single helical groove 24 is all identical with the wall thickness of titanium alloy fine-radial thin-wall pipes 1.
Actually add man-hour, described single helical groove 1 and single helical groove 24 also can adopt other fluting apparatus to process.
In the present embodiment, the diameter of described noble metal termination 2 is identical with the external diameter of titanium alloy fine-radial thin-wall pipes 1.The material of described noble metal termination 2 is platinum, and during actual use, 2 of noble metal terminations Detectable effects, follows the tracks of the position of far-end of the present invention.
In the present embodiment, the material of described titanium alloy fine-radial thin-wall pipes 1 is pure titanium, and the external diameter of described titanium alloy fine-radial thin-wall pipes 1 is that Φ 2mm and its wall thickness are 0.2mm.The groove width of described single helical groove 1 and single helical groove 24 is 0.01mm, and the pitch of described single helical groove 1 is 0.2mm, and the pitch of described single helical groove 24 is that gradient pitch and its increase progressively with 0.05mm from far near.The length L 1=50mm of described seal wire section far away, the length L 2=100mm in described seal wire stage casing, the length L 3=10mm of the nearly section of described seal wire.Actually add man-hour, can be according to specific needs, the groove width of single helical groove 1 and single helical groove 24 is adjusted accordingly within the scope of 0.01mm~0.2mm, also the pitch of single helical groove 1 can be adjusted accordingly within the scope of 0.2mm~0.5mm, and the pitch of single helical groove 24 increases progressively with 0.05mm~0.3mm from far near, the length L 3 of the length L 1 of described seal wire section far away, the length L 2 in seal wire stage casing and the nearly section of seal wire can adjust accordingly respectively within the scope of 5mm~50mm, 10mm~100mm and 10mm~200mm.
In the present embodiment, the titanium alloy seal wire of institute's machine-shaping can by adjust the length of single helical groove 1 and single helical groove 24 and pitch to the compliance of interventional guide wire and can be handling etc. performance adjust, to meet clinical different parts, use needs, it is convenient to realize, and can effectively overcome existing titanium alloy guide wire and number of drawbacks and the deficiency such as the course of processing is complicated, cost is high, bad adaptability.
During actual use, in described seal wire section far away, have uniform pitch helicla flute, thereby it can provide good compliance for interventional guide wire; Described seal wire has variable-pitch auger groove on stage casing, that is to say that variable-pitch auger groove is spiral involute structure, pitch increases gradually, can, for seal wire provides good pliability transition and outstanding handling and support force, make interventional guide wire there is good compliance, handling and enough support forces simultaneously.
Embodiment 2
In the present embodiment, as different from Example 1: the material of described noble metal termination 2 is gold, the material of described titanium alloy fine-radial thin-wall pipes 1 is Ti6Al4V titanium alloy, the external diameter of described titanium alloy fine-radial thin-wall pipes 1 is that Φ 0.5mm and its wall thickness are 0.1mm, the groove width of described single helical groove 1 and single helical groove 24 is 0.2mm, the pitch of described single helical groove 1 is 0.5mm, the pitch of described single helical groove 24 is that gradient pitch and its increase progressively with 0.3mm from far near, the length L 1=10mm of described seal wire section far away, the length L 2=90mm in described seal wire stage casing, the length L 3=200mm of the nearly section of described seal wire.
In the present embodiment, the structure of remainder is all identical with embodiment 1.
In the present embodiment, the titanium alloy seal wire of institute's machine-shaping can by adjust the length of single helical groove 1 and single helical groove 24 and pitch to the compliance of interventional guide wire and can be handling etc. performance adjust, to meet clinical different parts, use needs, it is convenient to realize, and can effectively overcome existing titanium alloy guide wire and number of drawbacks and the deficiency such as the course of processing is complicated, cost is high, bad adaptability.
Embodiment 3
In the present embodiment, as different from Example 1: the material of described noble metal termination 2 is platinumiridio, the material of described titanium alloy fine-radial thin-wall pipes 1 is Ti6Al7Nb titanium alloy, the external diameter of described titanium alloy fine-radial thin-wall pipes 1 is that Φ 2mm and its wall thickness are 0.2mm, the groove width of described single helical groove 1 and single helical groove 24 is 0.1mm, the pitch of described single helical groove 1 is 0.2mm, the pitch of described single helical groove 24 is that gradient pitch and its increase progressively with 0.1mm from far near, the length L 1=20mm of described seal wire section far away, the length L 2=100mm in described seal wire stage casing, the length L 3=200mm of the nearly section of described seal wire.
In the present embodiment, the structure of remainder is all identical with embodiment 1.
In the present embodiment, the titanium alloy seal wire of institute's machine-shaping can by adjust the length of single helical groove 1 and single helical groove 24 and pitch to the compliance of interventional guide wire and can be handling etc. performance adjust, to meet clinical different parts, use needs, it is convenient to realize, and can effectively overcome existing titanium alloy guide wire and number of drawbacks and the deficiency such as the course of processing is complicated, cost is high, bad adaptability.
Embodiment 4
In the present embodiment, as different from Example 1: the material of described titanium alloy fine-radial thin-wall pipes 1 is TiNi titanium alloy, the external diameter of described titanium alloy fine-radial thin-wall pipes 1 is that Φ 1mm and its wall thickness are 0.2mm, the groove width of described single helical groove 1 and single helical groove 24 is 0.1mm, the pitch of described single helical groove 1 is 0.2mm, the pitch of described single helical groove 24 is that gradient pitch and its increase progressively with 0.1mm from far near, the length L 1=30mm of described seal wire section far away, the length L 2=100mm in described seal wire stage casing, the length L 3=200mm of the nearly section of described seal wire.
In the present embodiment, the structure of remainder is all identical with embodiment 1.
In the present embodiment, the titanium alloy seal wire of institute's machine-shaping can by adjust the length of single helical groove 1 and single helical groove 24 and pitch to the compliance of interventional guide wire and can be handling etc. performance adjust, to meet clinical different parts, use needs, it is convenient to realize, and can effectively overcome existing titanium alloy guide wire and number of drawbacks and the deficiency such as the course of processing is complicated, cost is high, bad adaptability.
Embodiment 5
In the present embodiment, as different from Example 1: the material of described noble metal termination 2 is gold, the material of described titanium alloy fine-radial thin-wall pipes 1 is TiNi titanium alloy, the external diameter of described titanium alloy fine-radial thin-wall pipes 1 is that Φ 1mm and its wall thickness are 0.2mm, the groove width of described single helical groove 1 and single helical groove 24 is 0.1mm, the pitch of described single helical groove 1 is 0.3mm, the pitch of described single helical groove 24 is that gradient pitch and its increase progressively with 0.1mm from far near, the length L 1=10mm of described seal wire section far away, the length L 2=80mm in described seal wire stage casing, the length L 3=200mm of the nearly section of described seal wire.
In the present embodiment, the structure of remainder is all identical with embodiment 1.
In the present embodiment, the titanium alloy seal wire of institute's machine-shaping can by adjust the length of single helical groove 1 and single helical groove 24 and pitch to the compliance of interventional guide wire and can be handling etc. performance adjust, to meet clinical different parts, use needs, it is convenient to realize, and can effectively overcome existing titanium alloy guide wire and number of drawbacks and the deficiency such as the course of processing is complicated, cost is high, bad adaptability.
Embodiment 6
In the present embodiment, as different from Example 1: the material of described noble metal termination 2 is platinum, the material of described titanium alloy fine-radial thin-wall pipes 1 is TiNi titanium alloy, the external diameter of described titanium alloy fine-radial thin-wall pipes 1 is that Φ 1mm and its wall thickness are 0.3mm, the groove width of described single helical groove 1 and single helical groove 24 is 0.1mm, the pitch of described single helical groove 1 is 0.3mm, the pitch of described single helical groove 24 is that gradient pitch and its increase progressively with 0.1mm from far near, the length L 1=50mm of described seal wire section far away, the length L 2=100mm in described seal wire stage casing, the length L 3=10mm of the nearly section of described seal wire.
In the present embodiment, the structure of remainder is all identical with embodiment 1.
In the present embodiment, the titanium alloy seal wire of institute's machine-shaping can by adjust the length of single helical groove 1 and single helical groove 24 and pitch to the compliance of interventional guide wire and can be handling etc. performance adjust, to meet clinical different parts, use needs, it is convenient to realize, and can effectively overcome existing titanium alloy guide wire and number of drawbacks and the deficiency such as the course of processing is complicated, cost is high, bad adaptability.
Embodiment 7
In the present embodiment, as different from Example 1: the wall thickness of described titanium alloy fine-radial thin-wall pipes 1 is 0.4mm, the groove width of described single helical groove 1 and single helical groove 24 is 0.1mm, the pitch of described single helical groove 1 is 0.3mm, the pitch of described single helical groove 24 is that gradient pitch and its increase progressively with 0.2mm from far near, the length L 1=40mm of described seal wire section far away, the length L 2=50mm in described seal wire stage casing, the length L 3=80mm of the nearly section of described seal wire.
In the present embodiment, the structure of remainder is all identical with embodiment 1.
In the present embodiment, the titanium alloy seal wire of institute's machine-shaping can by adjust the length of single helical groove 1 and single helical groove 24 and pitch to the compliance of interventional guide wire and can be handling etc. performance adjust, to meet clinical different parts, use needs, it is convenient to realize, and can effectively overcome existing titanium alloy guide wire and number of drawbacks and the deficiency such as the course of processing is complicated, cost is high, bad adaptability.
Embodiment 8
In the present embodiment, as different from Example 1: the length L 1=5mm of described seal wire section far away, the length L 2=10mm in described seal wire stage casing, the length L 3=30mm of the nearly section of described seal wire.
In the present embodiment, the structure of remainder is all identical with embodiment 1.
In the present embodiment, the titanium alloy seal wire of institute's machine-shaping can by adjust the length of single helical groove 1 and single helical groove 24 and pitch to the compliance of interventional guide wire and can be handling etc. performance adjust, to meet clinical different parts, use needs, it is convenient to realize, and can effectively overcome existing titanium alloy guide wire and number of drawbacks and the deficiency such as the course of processing is complicated, cost is high, bad adaptability.
The above; it is only preferred embodiment of the present invention; not the present invention is imposed any restrictions, every any simple modification of above embodiment being done according to the technology of the present invention essence, change and equivalent structure change, and all still belong in the protection domain of technical solution of the present invention.

Claims (10)

1. a surgery interventional therapy titanium alloy seal wire, it is characterized in that: comprise titanium alloy fine-radial thin-wall pipes (1) and be laid in the noble metal termination (2) of titanium alloy fine-radial thin-wall pipes (1) far-end, described titanium alloy fine-radial thin-wall pipes (1) is divided into seal wire section far away, seal wire stage casing and the nearly section of seal wire three parts from far near, and described noble metal termination (2) is to be the hemispherical ends of coaxial laying with titanium alloy fine-radial thin-wall pipes (1); On the tube wall of described seal wire section far away, have single helical groove one (3), on the tube wall in described seal wire stage casing, have single helical groove two (4), described single helical groove one (3) is uniform pitch helicla flute, described single helical groove two (4) is variable-pitch auger groove, the groove width of described single helical groove one (3) and single helical groove two (4) is all identical, and the pitch of described single helical groove two (4) increases gradually from far near and the pitch of its far-end equates with the pitch of single helical groove one (3); The groove depth of described single helical groove one (3) and single helical groove two (4) is all identical with the wall thickness of titanium alloy fine-radial thin-wall pipes (1).
2. according to a kind of surgery interventional therapy titanium alloy seal wire claimed in claim 1, it is characterized in that: the external diameter of described titanium alloy fine-radial thin-wall pipes (1) is that Φ 2mm~Φ 0.5mm and its wall thickness are 0.4mm~0.1mm.
3. according to a kind of surgery interventional therapy titanium alloy seal wire described in claim 1 or 2, it is characterized in that: the material of described titanium alloy fine-radial thin-wall pipes (1) is pure titanium, Ti6Al4V titanium alloy, Ti6Al7Nb titanium alloy or TiNi titanium alloy.
4. according to a kind of surgery interventional therapy titanium alloy seal wire described in claim 1 or 2, it is characterized in that: the diameter of described noble metal termination (2) is identical with the external diameter of titanium alloy fine-radial thin-wall pipes (1).
5. according to a kind of surgery interventional therapy titanium alloy seal wire described in claim 1 or 2, it is characterized in that: the material of described noble metal termination (2) is platinum, gold or platinumiridio.
6. according to a kind of surgery interventional therapy titanium alloy seal wire described in claim 1 or 2, it is characterized in that: the groove width of described single helical groove one (3) and single helical groove two (4) is 0.01mm~0.2mm.
7. according to a kind of surgery interventional therapy titanium alloy seal wire described in claim 1 or 2, it is characterized in that: the pitch of described single helical groove one (3) is 0.2mm~0.5mm.
8. according to a kind of surgery interventional therapy titanium alloy seal wire claimed in claim 7, it is characterized in that: the pitch of described single helical groove two (4) is that gradient pitch and its increase progressively with 0.05mm~0.3mm from far near.
9. according to a kind of surgery interventional therapy titanium alloy seal wire described in claim 1 or 2, it is characterized in that: the length L 1=5mm~50mm of described seal wire section far away, length L 2=10mm~the 100mm in described seal wire stage casing, the length L 3=10mm~200mm of the nearly section of described seal wire.
10. according to a kind of surgery interventional therapy titanium alloy seal wire described in claim 1 or 2, it is characterized in that: described single helical groove one (3) and single helical groove two (4) are the helicla flute that adopts the molding of laser engraving machine engraving.
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CN105951015A (en) * 2016-05-25 2016-09-21 西部超导材料科技股份有限公司 Preparation method of Ti6Al7Nb titanium alloy fine-grain wire material
CN107789721A (en) * 2017-12-07 2018-03-13 刘召所 A kind of screw thread seal wire
CN107802942A (en) * 2017-11-15 2018-03-16 董鹏 A kind of medical guiding wire
CN110666461A (en) * 2019-10-21 2020-01-10 运怡(北京)医疗器械有限公司 Processing method of metal guide wire
CN111375116A (en) * 2014-11-04 2020-07-07 祥丰医疗私人有限公司 Duct support frame with gradually changed flexibility
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