CN104043192A - Disposable microneedle device - Google Patents
Disposable microneedle device Download PDFInfo
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- CN104043192A CN104043192A CN201410296973.4A CN201410296973A CN104043192A CN 104043192 A CN104043192 A CN 104043192A CN 201410296973 A CN201410296973 A CN 201410296973A CN 104043192 A CN104043192 A CN 104043192A
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- micropin
- base
- pedestal
- connecting rod
- variable color
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Abstract
The invention discloses a disposable microneedle device which comprises a base, a microneedle assembly, a cover and a plurality of connecting rods capable of being dissolved into ethyl alcohol. The microneedle assembly comprises a foundation base and a plurality of microneedles distributed on the foundation base at intervals. The top wall of the foundation base and the bottom wall of the base are respectively provided with conical grooves with the same number as the connecting rods, the two tail ends of each connecting rod are in a conical shape, one tail end of each connecting rod is embedded into one corresponding conical groove in the bottom wall of the base, the other tail end of each connecting rod is embedded into one corresponding conical groove in the top wall of the foundation base, the connecting rods are arranged at intervals to form a regular triangular array, the cover is detachably buckled to the base, a closed space is formed between the cover and the base, and the microneedle assembly and the connecting rods are located in the closed space. The disposable microneedle device can be effectively prevented from being used twice, and cross infection is fundamentally avoided.
Description
Technical field
The present invention relates to a kind of disposable microneedle devices.
Background technology
Because the micropin of microneedle devices is sharp short and small, and keratodermatitis does not have nervous tissue and blood vessel, therefore while use, can not produce pain and bleeding, and the aperture of Wicresoft can heal within very short time, therefore make microneedle devices not only be widely used in medical administration, be also widely used in promoting absorption and the infiltration of cosmetics.
Existing microneedle devices generally comprises base and microneedle array assembly, and this microneedle array assembly is fixed on this base by viscose.In practical application, some beauty parlor, for saving cost, can reuse used microneedle devices after ethanol simply immersing, so, can bring the risk of cross infection to user, gently skin allergy is as dry, red and swollen, heavy disfeature or infect infectious disease.In addition, whether user also cannot use by observing intuitively differentiation microneedle devices, was unfavorable for safeguarding self lawful right.
When user passes through microneedle devices administration, generally press microneedle array, make microneedle array moment produce the duct of a large amount of micron dimension sizes at keratodermatitis and epidermal area, take again microneedle devices away, medicine is applied in to skin, and medicine can be realized rapid osmotic and diffusion in percutaneous duct, and this kind of mode causes medicine to be polluted by airborne impurity sometimes, affect drug effect, and operational efficiency is lower.
Summary of the invention
For the deficiencies in the prior art, object of the present invention is intended to provide a kind of disposable microneedle devices that prevents that secondary from using.
For achieving the above object, the present invention adopts following technical scheme:
A kind of disposable microneedle devices, it comprises base, micropin assembly, lid and some connecting rods that is dissolvable in water ethanol;
This micropin assembly comprises pedestal and is located at the micropin some spaced apart on pedestal; The roof of this pedestal respectively offers with on the diapire of this base the conical socket that quantity is identical with connecting rod; All tapered shapes of two ends of each connecting rod, a wherein end of each connecting rod is flush-mounted in correspondence one conical socket of diapire of this base, and another end of each connecting rod is flush-mounted in correspondence one conical socket of roof of this pedestal; Some connecting rods are spaced and form a Triangular array;
This lid is removably fastened on this base, between this lid and this base, forms a confined space, and this micropin assembly and connecting rod are positioned at this confined space.
Further, this micropin assembly also comprises some chance water and the variable color part of variable color, and the quantity of variable color part is identical with the quantity of micropin, and variable color part is corresponding one by one with micropin; Some micropins form a crisscross microneedle array; Each variable color part is fixed on pedestal, and is sheathed on outside the upper end of a corresponding micropin.
Further, the tapered shape of each micropin; Each variable color part is semi-spherical shape, and the conical through-hole that runs through sphere and bottom surface is offered at its middle part, and each variable color part is sheathed on outside the upper end of a corresponding micropin by this conical through-hole.
Further, this variable color part is discolour silica gel part.
Further, in this base, offer a liquid storage cylinder, the diapire of this base is offered the liquid outlet of this liquid storage cylinder of connection, in this pedestal, offer a horizontal drain passage, the sidewall of this pedestal is offered the inlet of this horizontal drain passage of a connection, and the liquid outlet of this base is communicated with the inlet of this pedestal by a catheter; In each micropin, offer the drain passage of this horizontal drain passage of a connection.
Further, the terminal surface of each micropin is one domatic.
Further, this connecting rod is the connecting rod of being made up of novolac resin.
Further, this pedestal and micropin are by metal or monocrystal silicon is one-body molded makes.
Beneficial effect of the present invention is as follows:
1, connecting rod of the present invention forms the supporting construction of a firm Triangular array, can make this micropin assembly be fixed on securely on this base.When user is want to use this device by sterilization secondary, and when disposable basis microneedle devices is soaked in to ethanol, because some connecting rods are spaced, each connecting rod can be fully and Ethanol Exposure, accelerate the dissolving of connecting rod, the connecting rod at three angles that is distributed in this Triangular array is dissolved fast, thereby can destroy fast this supporting construction, this micropin assembly is come off from this base, effectively prevent from again utilizing this microneedle devices, fundamentally avoid cross infection, the array of other shapes relatively, this Triangular array can have firm support and rapidly-soluble effect concurrently.
2, user can be by observing intuitively the color of variable color part, to judge that whether this device is for using first.
3, the percutaneous aperture of relatively traditional medicinal liquid enters skin surface, this device directly imports skin surface by drain passage by medicinal liquid, not only improves operational efficiency, and avoids medicinal liquid by outside contamination, pollution-free medicinal liquid directly can be imported to skin, fast health.
Brief description of the drawings
Fig. 1 is the local longitudinal profile schematic diagram of the preferred embodiments of the disposable microneedle devices of the present invention;
Fig. 2 is the horizontal section schematic diagram of the disposable microneedle devices of Fig. 1;
Fig. 3 is the local elevational schematic view of the micropin assembly of the disposable microneedle devices of Fig. 1.
Detailed description of the invention
Below in conjunction with accompanying drawing and detailed description of the invention, the present invention is described further:
Refer to Fig. 1 to Fig. 3, the present invention relates to a kind of disposable microneedle devices, its preferred embodiments comprises base 10, micropin assembly 40, lid 20 and some connecting rods 30 that is dissolvable in water ethanol.
This micropin assembly 40 comprises pedestal 41 and is located at the micropin 43 some spaced apart on pedestal 41.Some micropins 43 are one-body molded with pedestal 41.On the diapire of the roof of this pedestal 41 and this base 10, respectively offer the conical socket that quantity is identical with connecting rod 30.All tapered shapes of two ends of each connecting rod 30, a wherein end of each connecting rod 30 is flush-mounted in correspondence one conical socket of diapire of this base 10, and another end of each connecting rod 30 is flush-mounted in correspondence one conical socket of roof of this pedestal 41.Some connecting rods 30 are spaced and form a Triangular array.
So, this Triangular array forms a firm supporting construction, can make this micropin assembly 40 be fixed on securely on this base 10.After this disposable microneedle devices was used once, user is want to use by sterilization secondary, and when disposable basis microneedle devices is soaked in to ethanol, because some connecting rods 30 are spaced, each connecting rod 30 can be fully and Ethanol Exposure, accelerate the dissolving of connecting rod 30, the connecting rod 30 at three angles that is distributed in this Triangular array is dissolved fast, thereby can destroy fast this supporting construction, this micropin assembly 40 is come off from this base 10, effectively prevent from again utilizing this microneedle devices, fundamentally avoid cross infection, the array of other shapes relatively, this Triangular array can have firm support and rapidly-soluble effect concurrently.
This connecting rod 30 can adopt any shape component admittedly that can be dissolved in ethanol in prior art as all kinds of phenolic resins, preferably, can adopt novolac resin, exhaustive no longer one by one at this.
This lid 20 is removably fastened on this base 10, between this lid 20 and this base 10, forms a confined space, and this micropin assembly 40 and connecting rod 30 are all positioned at this confined space, thereby can ensure that micropin assembly 40 avoids being polluted by steam and dust.
This micropin assembly 40 also comprises some chance water and the variable color part 42 of variable color, and the quantity of variable color part 42 is identical with the quantity of micropin 43, and variable color part 42 is corresponding one by one with micropin 43.Some micropins 43 form a crisscross microneedle array.Each variable color part 42 is fixed on pedestal 41, and is sheathed on outside the upper end of a corresponding micropin 43.
The tapered shape of each micropin 43.Each variable color part 42 is semi-spherical shape, can increase the contact area of variable color part 42 and moisture, increases variable color efficiency, and the conical through-hole that runs through sphere and bottom surface is offered at its middle part, and each variable color part 42 is sheathed on outside the upper end of a corresponding micropin 43 by this conical through-hole.
Off-color material and metachromatic principle that this variable color part 42 adopts can be known by prior art, as this variable color part 42 can be discolour silica gel part, exhaustive no longer one by one at this.Before use, the micropin assembly 40 of this device is contained in confined space, thereby variable color part 42 is isolated with moisture or ethanol, guarantees that variable color part 42 keeps primary colors, and thus, user can determine that the microneedle devices after sealing off is to use first intuitively.In the time that micropin 43 injects skin, variable color part 42 is close to skin, and the sweat of skin surface contains moisture, discolour silica gel part absorbs moisture and becomes redness from blueness, so, user can confirm that this microneedle devices was used intuitively by variable color part 42, thereby no longer reuses.Moreover this variable color part 42 also plays position-limiting action, can make micropin assembly 40 more fit and contact with skin.In addition, in the time that user is soaked in ethanol by microneedle devices, owing to comprising moisture in ethanol, this variable color part 42 also can variable color.
In this base 10, offer a liquid storage cylinder 412, the diapire of this base 10 is offered the liquid outlet of this liquid storage cylinder 412 of a connection.In this pedestal 41, offer a horizontal drain passage, the sidewall of this pedestal 41 is offered the inlet of this horizontal drain passage of a connection, the liquid outlet of this base 10 is communicated with the inlet of this pedestal 41 by a catheter 413, offer the drain passage 431 of this horizontal drain passage of a connection in each micropin 43.So, user can import medicinal liquid in this liquid storage cylinder 412 in advance, again micropin 43 is injected to skin, the medicinal liquid of liquid storage cylinder 412 will flow into the horizontal drain passage of this pedestal 41 via catheter 431, and be delivered to each drain passage 431 by this horizontal drain passage, to flow into skin surface, the percutaneous aperture of relatively traditional medicinal liquid enters skin surface, this device directly imports skin surface by drain passage 431 by medicinal liquid, not only improve operational efficiency, and avoid medicinal liquid by the contaminating impurity of air, pollution-free medicinal liquid directly can be imported to skin, health fast.
The terminal surface of each micropin 43 is one domatic, so, can make the sharper and frangibility not of micropin 43.
This pedestal 41 and micropin 43 are by metal or monocrystal silicon is one-body molded makes, thereby can make not frangibility of micropin 43.
For a person skilled in the art, can be according to technical scheme described above and design, make other various corresponding changes and distortion, and these all changes and distortion all should belong to the protection domain of the claims in the present invention within.
Claims (8)
1. a disposable microneedle devices, is characterized in that: it comprises base, micropin assembly, lid and some connecting rods that is dissolvable in water ethanol;
This micropin assembly comprises pedestal and is located at the micropin some spaced apart on pedestal; The roof of this pedestal respectively offers with on the diapire of this base the conical socket that quantity is identical with connecting rod; All tapered shapes of two ends of each connecting rod, a wherein end of each connecting rod is flush-mounted in correspondence one conical socket of diapire of this base, and another end of each connecting rod is flush-mounted in correspondence one conical socket of roof of this pedestal; Some connecting rods are spaced and form a Triangular array;
This lid is removably fastened on this base, between this lid and this base, forms a confined space, and this micropin assembly and connecting rod are positioned at this confined space.
2. disposable microneedle devices as claimed in claim 1, is characterized in that: this micropin assembly also comprises some chance water and the variable color part of variable color, and the quantity of variable color part is identical with the quantity of micropin, and variable color part is corresponding one by one with micropin; Some micropins form a crisscross microneedle array; Each variable color part is fixed on pedestal, and is sheathed on outside the upper end of a corresponding micropin.
3. disposable microneedle devices as claimed in claim 2, is characterized in that: the tapered shape of each micropin; Each variable color part is semi-spherical shape, and the conical through-hole that runs through sphere and bottom surface is offered at its middle part, and each variable color part is sheathed on outside the upper end of a corresponding micropin by this conical through-hole.
4. disposable microneedle devices as claimed in claim 2, is characterized in that: this variable color part is discolour silica gel part.
5. disposable microneedle devices as claimed in claim 1, it is characterized in that: in this base, offer a liquid storage cylinder, the diapire of this base is offered the liquid outlet of this liquid storage cylinder of connection, in this pedestal, offer a horizontal drain passage, the sidewall of this pedestal is offered the inlet of this horizontal drain passage of a connection, and the liquid outlet of this base is communicated with the inlet of this pedestal by a catheter; In each micropin, offer the drain passage of this horizontal drain passage of a connection.
6. disposable microneedle devices as claimed in claim 5, is characterized in that: the terminal surface of each micropin is one domatic.
7. disposable microneedle devices as claimed in claim 1, is characterized in that: this connecting rod is the connecting rod of being made up of novolac resin.
8. disposable microneedle devices as claimed in claim 1, is characterized in that: this pedestal and micropin are by metal or monocrystal silicon is one-body molded makes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410296973.4A CN104043192B (en) | 2014-06-28 | 2014-06-28 | Disposable microneedle devices |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410296973.4A CN104043192B (en) | 2014-06-28 | 2014-06-28 | Disposable microneedle devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104043192A true CN104043192A (en) | 2014-09-17 |
| CN104043192B CN104043192B (en) | 2016-08-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410296973.4A Active CN104043192B (en) | 2014-06-28 | 2014-06-28 | Disposable microneedle devices |
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| CN (1) | CN104043192B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106726547A (en) * | 2016-08-31 | 2017-05-31 | 吴月丽 | Acupuncture needle show |
| CN109475729A (en) * | 2016-07-21 | 2019-03-15 | 昂热大学 | Implantable medical device for locally injecting |
| CN111107839A (en) * | 2017-08-11 | 2020-05-05 | Lts勒曼治疗系统股份公司 | Microneedle array with color transition indicator |
| WO2021036076A1 (en) * | 2019-08-23 | 2021-03-04 | 苏州纳生微电子有限公司 | Quantitative liquid supply device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| CN102327656A (en) * | 2011-10-18 | 2012-01-25 | 清华大学 | Disposable array miniature injection needle head |
| CN202314939U (en) * | 2010-11-10 | 2012-07-11 | 吉林大学 | Easy painless medicine infusing device |
| CN204073087U (en) * | 2014-06-28 | 2015-01-07 | 陈彦彪 | Disposable microneedle devices |
-
2014
- 2014-06-28 CN CN201410296973.4A patent/CN104043192B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| CN202314939U (en) * | 2010-11-10 | 2012-07-11 | 吉林大学 | Easy painless medicine infusing device |
| CN102327656A (en) * | 2011-10-18 | 2012-01-25 | 清华大学 | Disposable array miniature injection needle head |
| CN204073087U (en) * | 2014-06-28 | 2015-01-07 | 陈彦彪 | Disposable microneedle devices |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109475729A (en) * | 2016-07-21 | 2019-03-15 | 昂热大学 | Implantable medical device for locally injecting |
| CN106726547A (en) * | 2016-08-31 | 2017-05-31 | 吴月丽 | Acupuncture needle show |
| CN111107839A (en) * | 2017-08-11 | 2020-05-05 | Lts勒曼治疗系统股份公司 | Microneedle array with color transition indicator |
| CN111107839B (en) * | 2017-08-11 | 2023-11-10 | Lts勒曼治疗系统股份公司 | Microneedle array with color transition indicator |
| WO2021036076A1 (en) * | 2019-08-23 | 2021-03-04 | 苏州纳生微电子有限公司 | Quantitative liquid supply device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104043192B (en) | 2016-08-24 |
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Effective date of registration: 20161128 Address after: Panyu District of Guangzhou City, Guangdong province 510000 Xiaoguwei Street Outer Ring Road No. 280 Building No. 225, a department of Guangdong Pharmaceutical University Patentee after: Guangzhou gunnery Biotechnology Co. Ltd. Address before: 522000 Guangdong province Jieyang City Airport district town Room Seven Tu Wei village in Xinxiang Patentee before: Chen Yanbiao |