CN104345036B - blood component analyzer - Google Patents
blood component analyzer Download PDFInfo
- Publication number
- CN104345036B CN104345036B CN201310398022.3A CN201310398022A CN104345036B CN 104345036 B CN104345036 B CN 104345036B CN 201310398022 A CN201310398022 A CN 201310398022A CN 104345036 B CN104345036 B CN 104345036B
- Authority
- CN
- China
- Prior art keywords
- blood
- test piece
- blood component
- light
- component analyser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000012503 blood component Substances 0.000 title claims abstract description 45
- 239000008280 blood Substances 0.000 claims description 44
- 210000004369 blood Anatomy 0.000 claims description 44
- 239000000463 material Substances 0.000 claims description 23
- 239000000203 mixture Substances 0.000 claims description 7
- 238000001727 in vivo Methods 0.000 claims description 4
- 238000010241 blood sampling Methods 0.000 abstract description 3
- 238000010586 diagram Methods 0.000 description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 238000010295 mobile communication Methods 0.000 description 3
- 239000012491 analyte Substances 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/8483—Investigating reagent band
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/022—Casings
- G01N2201/0221—Portable; cableless; compact; hand-held
Abstract
A blood component analyzer comprises a body, a blood sampling device in the body, and a test piece in the body. The body comprises a first surface which is not light-permeable and a second surface which is light-permeable, and a first inner surface of the body is designed to reflect a light ray input through the second surface in the body.
Description
Technical field
The present invention relates to a kind of blood component analyser (Blood Analyte Meter), more particularly to a kind of integration are adopted
Blood device and blood component analyser of the test piece (test strip) in same housing.
Background technology
Traditional blood component analyser basically comprises blood-taking device separated from one another and test piece.That is, using
After person needs first to allow blood-taking device (a possibly blood taking needle) to puncture its finger surface, then blood model (blood
Sample) drip in test piece.Collecting the test piece of blood model would generally insert the slot of a blood component reading device, with complete
The estimation of specific composition numerical value in blood model.
In addition, color change of the existing test piece after blood model has been collected even with photographing unit image
Capture, may be because of the relation of ambient light so that the image for being captured can not accurately reflect real in blood model
The situation of the blood component numerical value on border.If again temperature, this can affect what this parameter of test piece color appearance was taken into account
Words, existing test piece image capture might not the close actual numerical value of output result.
The content of the invention
It is an object of the present invention to provide a kind of blood component analyser, the composition numerical value that can lift blood model is sentenced
Disconnected accuracy.
A kind of blood component analyser (blood analyte meter) of present invention invention includes a body, a blood sampling
Device is located within the body and a test piece (test strip) is similarly positioned in this in vivo.Body includes lighttight 1 first
One second surface of surface and printing opacity, and one first inner surface of body be designed to can body interior reflection via this second
One light of surface input.
The present invention is that blood-taking device and test piece are incorporated in same blood component analyser housing/structure.User
In addition the slot that test piece is inserted into blood component reading device just need not can be obtained blood component numerical value.In addition, this
The first surface (for example, the upper surface of housing) of bright blood component analyser housing is a lighttight design,
Can effectively block ambient light for blood glucose test color change acquisition caused by impact.
Add, the blood component analyser of the present invention is substantially to coordinate device for mobile communication (such as mobile phone) to use.
That is the image of test piece is captured by photographing unit attached on device for mobile communication, thus when the present invention blood into
The second surface of only housing can be to allow the light of above-mentioned photographing unit to lead to when part analyser is placed on device for mobile communication
Cross, the acquisition of test piece image is completed under the interference without too many ambient light, to guarantee the accuracy that numerical value judges.
Describe the present invention below in conjunction with the drawings and specific embodiments, but it is not as a limitation of the invention.
Description of the drawings
Fig. 1 is the schematic diagram according to the blood component analyser of one embodiment of the invention；
Fig. 2 is the schematic diagram according to the blood component analyser of one embodiment of the invention；And
Fig. 3 is the schematic diagram according to the blood component analyser of one embodiment of the invention.
Wherein, reference
100th, 200,300 blood component analyser
102nd, 202,302 housing
104th, 204,304 test piece
106th, 206,306 blood-taking device
108th, 208,305 first surface
112nd, 212,322 second surface
113rd, 218,324 internal light source
114th, 222,326 flexible material layers
214th, 312,316 opening
216 blood transfusion passages
First precalculated position of 308 first surfaces
First precalculated position of 314 test pieces
Specific embodiment
The structural principle and operation principle of the present invention are described in detail below in conjunction with the accompanying drawings：
Fig. 1 is referred to, Fig. 1 is the schematic diagram according to the blood component analyser 100 of one embodiment of the invention.Blood component
Analyser 100 is comprising a housing 102, a test piece 104 is located in housing 102 and a blood-taking device 106 is similarly positioned in housing
In 102.Housing 102 has additionally comprised a first surface 108 and a second surface 112.On first surface 108 one first makes a reservation for
Position is can be designed to allow blood-taking device 104 to protrude from when being activated outside housing 102, has been connect with the finger with user
Touch.One second precalculated position of first surface 108 can have the setting of an opening 105 so that when the finger of user is with blood sampling dress
Putting be able to after 106 contacts, blood model (blood sample) can be collected by test piece 104 by opening 105.
When blood model was collected in test piece 104, test piece 104 has the change in color.And the color of this test piece 104,
When the light that the photographing unit set up of the screen light source irradiation using mobile phone or mobile phone sends irradiates, less easily by ring
The impact of border light so that judge that the blood component numerical value in collected blood model can via the color of test piece 104
It is more accurate.And in order to effectively block the impact of ambient light, first surface 108 is designed as a lighttight surface and the second table
Face 112 then can be the surface of light-permeable.Because second surface 112 is light-permeable, an external light source is (as mobile phone screen sends
Light) can be input in the housing 102 of blood component analyser 100 via second surface 112.
In addition, in order to the external light source provided in the case where excessive ambient light interference is not needed makes enough test piece 104
Image is successfully subtracted, and the interior surface (such as the first inner surface) of housing 102 is arranged to reflexible state.Housing
Can in addition there be the setting of a light source 113 102 inside, and the light that this light source 113 is sent will not be exported via first surface 108
To outside housing 102, and will have an opportunity to rest on the internal reflection of housing 102 so that the image of test piece 104 can be picked successfully
Take.
The change of color is different from each other at different ambient temperatures in test piece 104.So the inside of housing 102 can be arranged in addition
The one reference zone (not shown) that can change colour with an ambient temperature.In one embodiment, above-mentioned reference zone is to be located at test piece
104 periphery.There is the change in color because of varying environment temperature because reference zone is same, when the image quilt of test piece 104
During acquisition, the image of reference zone is equally subtracted, and can reflect because shown by the test piece 104 caused by ambient temperature
Change so that the composition numerical value of the blood model measured under different temperatures can relatively accurately it is estimated out.
Blood component analyser 100 can additionally comprise flexible material (flexible material) layer 114.This can
A part that material layers 114 can be second surface 112 or the lower section for being arranged at second surface 112 are scratched, with blood component point
Body surface (such as desktop) contact that analyzer 100 is put.When blood component analyser 100 is pressed down against (such as user
Finger when being placed to opening 105) this flexible material layers 114 therefore can form suction to blood model by compression, to help
Test piece 104 is helped for the collection of blood model.The setting of flexible material layers 114, can equally help blood component analyser 100
Put body surface can be fixed on, be not to produce unnecessary movement, can equally help test piece 104 for blood
The collection of model.
When flexible material layers 114 are in the lower section of second surface 112, flexible material layers 114 need to allow to come from outside
The light of light source is obtained through (penetrable), and passes through the light of flexible material layers 114 and second surface 112 can be in shell
The internal reflection of body 102, allows test piece 104 smoothly to be captured with the image of reference zone to provide enough light quantities.
Blood-taking device 106 can be implemented in the way of a microneedle array (micro needle array).Flexible material
Layer 114 can be a rubber (rubber) or a silica gel (silicone) composition.
Fig. 2 is referred to, Fig. 2 is the schematic diagram according to the blood component analyser 200 of one embodiment of the invention.Blood into
Part analyser 200 is comprising a housing 202, a test piece 204 is located in housing 202 and a blood-taking device 206 is similarly positioned in housing
In 202.
Housing 202 has additionally comprised a first surface 208 and a second surface 212.On first surface 208 one first is pre-
It is can be designed to allow blood-taking device 204 to protrude from when being activated outside housing 202 that positioning is put, with the finger of user
Contact.
One second precalculated position of first surface 208 can have the setting of an opening 214, and this opening 214 is by a blood transfusion
Passage 216 is connected with test piece 204.After the finger of user is contacted with blood-taking device 206, blood model can pass through opening
214 are collected with blood transfusion passage 216 by test piece 204.In one embodiment, passage 216 of transfusing blood is a capillary tube, can be delivered in
The blood model of opening 214 is to test piece 204.
Similar to blood component analyser 100, the first outer surface 208 of blood component analyser 200 can not printing opacity and its
Second surface 212 then can be with printing opacity.It is so designed that, the inside of housing 202 of blood component analyser 200 will can be allowed not have and wear
Thoroughly the ambient light of first surface 208 and only penetrate the internal reflection of the light in housing 202 of second surface 212.So, examination
Piece 204 (blood model that it is collected equally can the coloured change because of different temperatures) be similarly disposed at housing 202
Internal meeting can be favorably accomplished with the image capture of the reference zone of temperature discoloring.
The inside of housing 202 can be provided with an internal light source 218, and the light that this internal light source 218 is sent equally can be in shell
Body 202 is configured to the inside of reflexible state and has reflected, and helps the image capture of above-mentioned test piece 204 and reference zone.
In addition, blood component analyser 200 can include a flexible material layers 222.This flexible material layers 222 can be
A part for second surface 212 or it is arranged on the lower section of second surface 212.Flexible material layers 222 are designed to light-permeable
State, particularly when flexible material layers 222 are arranged on the lower section of second surface 212.By the skin-friction force that offer is larger,
Flexible material layers 222 can also help fix whole housing 202 in the body surface put.
Fig. 3 is referred to, Fig. 3 is the schematic diagram according to the blood component analyser 300 of one embodiment of the invention.Blood into
Part analyser 300 is comprising a housing 302, a test piece 304 is located in housing 302 and a blood-taking device 306 is similarly positioned in housing
In 102.
Housing 102 has additionally comprised a first surface 305.One first precalculated position 308 on first surface 305 is design
There is an opening 312, while equally there is an opening 316 in one first precalculated position 314 in blood glucose test 304 to allow blood-taking device
306 pass through when being activated, and have been contacted with the finger with user.After the finger of user is contacted with blood-taking device 306
So that blood model can be collected by blood glucose test 304.First precalculated position 314 of test piece 304 corresponds to first surface
305 the first precalculated position 308 so that test piece 304 can smoothly be implemented for the collection of blood model.
When blood model was collected in test piece 304, test piece 304 has the change in color.And the color of this test piece 304,
When the light that the photographing unit set up of the screen light source irradiation using mobile phone or mobile phone sends irradiates, less easily by ring
The impact of border light so that judge that the composition numerical value in collected blood model can be more via the color of test piece 304
Accurately.And in order to effectively block the impact of ambient light, first surface 305 is designed as a lighttight surface.And second surface
322 surfaces that can be light-permeable, an external light source (such as the light that mobile phone screen is sent) can be defeated via second surface 322
Enter in the housing 302 of blood component analyser 300.
In addition, in order to the external light source provided in the case where excessive ambient light interference is not needed makes enough test piece 304
Image is successfully subtracted, and the interior surface (such as the first inner surface) of housing 302 is arranged to reflexible state.Housing
Can in addition there be the setting of a light source 324 302 inside, and the light that this light source 324 is sent will not be exported via first surface 305
To outside housing 302, and will have an opportunity to rest on the internal reflection of housing 302 so that the image of test piece 304 can be picked successfully
Take.
Because the change of color is different from each other at different ambient temperatures in test piece 304, the inside of housing 302 can be in addition
The one reference zone (not shown) that can change colour with an ambient temperature is set.In one embodiment, above-mentioned reference zone is to be located at
The periphery of test piece 304.There is the change in color because of varying environment temperature because reference zone is same, when the shadow of test piece 304
As when being subtracted, the image of reference zone is equally subtracted, and can reflect because the test piece 304 caused by ambient temperature shows
The color change shown so that the composition numerical value of the blood model measured under different temperatures can relatively accurately it is estimated out.
Blood component analyser 300 can additionally comprise a flexible material layers 326.This flexible material layers 326 can be
The part on two surfaces 322 or the lower section of second surface 322 is arranged at, the object put with blood component analyser 300
Surface (such as desktop) contacts.When blood component analyser 300 is pressed down against, (finger such as user is placed to opening 312
When), therefore this flexible material layers 326 can be formed the negative pressure to blood model (negative pressure) suction by compression,
To help test piece 304 for the collection of blood model.
The setting of flexible material layers 326, can equally help blood component analyser 300 to be fixed on put thing
Body surface face, is not to produce unnecessary movement, can equally help test piece 304 for the collection of blood model.
When flexible material layers 326 are in the lower section of second surface 322, flexible material layers 326 need to allow to come from outside
The light of light source is obtained through (penetrable), and passes through the light of flexible material layers 326 and second surface 322 can be in shell
The internal reflection of body 302, allows blood glucose test 304 smoothly to be captured with the image of reference zone to provide enough light quantities.
Certainly, the present invention can also have other various embodiments, ripe in the case of without departing substantially from spirit of the invention and its essence
Know those skilled in the art and work as and various corresponding changes and deformation, but these corresponding changes and change can be made according to the present invention
Shape should all belong to the protection domain of appended claims of the invention.
Claims (7)
1. a kind of blood component analyser, for carrying out acquisition analysis to the image of a test piece, it is characterised in that include：
One body；
One blood-taking device is located at this in vivo；
The test piece is located at this in vivo；
One blood transfusion passage is connected with the test piece, and wherein the body includes one second table of a lighttight first surface and printing opacity
Face, and one first inner surface of the body is the light that can be input into via the second surface in body interior reflection；With
And
One light-emitting device is located at this in vivo, and the light wherein produced by the light-emitting device will not be via the first surface output
To outside the body, but can reflect in the body interior for first inner surface so that the image of the test piece can be successfully
It is subtracted.
2. blood component analyser according to claim 1, it is characterised in that one first precalculated position of the first surface
It is for outside the blood-taking device is activated and enables the blood-taking device to protrude from the body.
3. blood component analyser according to claim 1, it is characterised in that one second precalculated position of the first surface
An opening is provided with for enabling the test piece to collect a blood model.
4. blood component analyser according to claim 3, it is characterised in that corresponding to the one the of the opening in the test piece
One precalculated position is to allow the blood-taking device to pass through when the blood-taking device is activated.
5. blood component analyser according to claim 1, it is characterised in that additionally comprise a flexible material layers.
6. blood component analyser according to claim 1, it is characterised in that the blood-taking device is a microneedle array.
7. blood component analyser according to claim 1, it is characterised in that the body interior has additionally comprised can
The reference zone changed colour with an ambient temperature be used for comparing in the test piece to should be shown by ambient temperature color change, and then
Extrapolate the composition numerical value of the blood model measured under different temperatures.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW102128741A TWI533844B (en) | 2013-08-09 | 2013-08-09 | Blood analyte meter |
| TW102128741 | 2013-08-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104345036A CN104345036A (en) | 2015-02-11 |
| CN104345036B true CN104345036B (en) | 2017-05-17 |
Family
ID=52501101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310398022.3A Expired - Fee Related CN104345036B (en) | 2013-08-09 | 2013-09-04 | blood component analyzer |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN104345036B (en) |
| TW (1) | TWI533844B (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1112717A1 (en) * | 1996-12-06 | 2001-07-04 | Abbott Laboratories | Apparatus suitable for obtaining blood samples in a diagnostic test |
| CN1522366A (en) * | 2002-04-02 | 2004-08-18 | ����˹ҽ������˾ | Integrated sample testing meter |
| CN101547632A (en) * | 2006-12-07 | 2009-09-30 | 霍夫曼-拉罗奇有限公司 | Device and method for analyzing body fluids |
| CN201905880U (en) * | 2011-01-07 | 2011-07-27 | 郝天羽 | Household easy instrument for monitoring neonatal jaundice |
| CN201920706U (en) * | 2011-01-07 | 2011-08-10 | 郝天羽 | Home monitoring system for neonatal jaundice |
| CN201939330U (en) * | 2011-01-07 | 2011-08-24 | 郝天羽 | Network monitoring system for icterus neonatorum |
| WO2013104671A1 (en) * | 2012-01-10 | 2013-07-18 | Sanofi-Aventis Deutschland Gmbh | A blood analysis meter |
-
2013
- 2013-08-09 TW TW102128741A patent/TWI533844B/en not_active IP Right Cessation
- 2013-09-04 CN CN201310398022.3A patent/CN104345036B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1112717A1 (en) * | 1996-12-06 | 2001-07-04 | Abbott Laboratories | Apparatus suitable for obtaining blood samples in a diagnostic test |
| CN1522366A (en) * | 2002-04-02 | 2004-08-18 | ����˹ҽ������˾ | Integrated sample testing meter |
| CN101547632A (en) * | 2006-12-07 | 2009-09-30 | 霍夫曼-拉罗奇有限公司 | Device and method for analyzing body fluids |
| CN201905880U (en) * | 2011-01-07 | 2011-07-27 | 郝天羽 | Household easy instrument for monitoring neonatal jaundice |
| CN201920706U (en) * | 2011-01-07 | 2011-08-10 | 郝天羽 | Home monitoring system for neonatal jaundice |
| CN201939330U (en) * | 2011-01-07 | 2011-08-24 | 郝天羽 | Network monitoring system for icterus neonatorum |
| WO2013104671A1 (en) * | 2012-01-10 | 2013-07-18 | Sanofi-Aventis Deutschland Gmbh | A blood analysis meter |
Also Published As
| Publication number | Publication date |
|---|---|
| TWI533844B (en) | 2016-05-21 |
| CN104345036A (en) | 2015-02-11 |
| TW201505608A (en) | 2015-02-16 |
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