CN105662533A - Blood-vessel embolectomy device with helical structure and thrombus treating apparatus with the same - Google Patents

Blood-vessel embolectomy device with helical structure and thrombus treating apparatus with the same Download PDF

Info

Publication number
CN105662533A
CN105662533A CN201610009736.4A CN201610009736A CN105662533A CN 105662533 A CN105662533 A CN 105662533A CN 201610009736 A CN201610009736 A CN 201610009736A CN 105662533 A CN105662533 A CN 105662533A
Authority
CN
China
Prior art keywords
taking
thrombus
helical structure
bolt device
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610009736.4A
Other languages
Chinese (zh)
Other versions
CN105662533B (en
Inventor
赵中
陈志刚
徐兵科
施磊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhuhai trans Bridge Medical Technology Co., Ltd.
Original Assignee
赵烜
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 赵烜 filed Critical 赵烜
Priority to CN201610009736.4A priority Critical patent/CN105662533B/en
Publication of CN105662533A publication Critical patent/CN105662533A/en
Application granted granted Critical
Publication of CN105662533B publication Critical patent/CN105662533B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • A61B2017/22042Details of the tip of the guide wire
    • A61B2017/22044Details of the tip of the guide wire with a pointed tip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2215Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having an open distal end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1052Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector

Abstract

The invention relates to a blood-vessel embolectomy device with a helical structure and a thrombus treating apparatus with the same. The blood-vessel embolectomy device comprises a developing loop, developing rings and an embolectomy device body arranged between the developing loop and the developing rings. The embolectomy device body is of a web-tubular or cage-shaped structure composed of a plurality of connected unit grids; the web-shaped or cage-shaped structure is in an opening type, and a longitudinal gap is formed in the side face of the embolectomy device body, and extends in a helical mode along the outer surface of the web-shaped or cage-shaped structure. The thrombus treating apparatus comprises the blood-vessel embolectomy device with the helical structure, a protecting sheath tube, a conveying wire, a micro guide tube, a guiding guide tube and a rotating bleeding stopping valve. The micro guide tube is pushed to a thrombus embolism in the guiding guide tube along the guiding guide tube, the protecting sheath tube is communicated with the micro guide tube through the rotating bleeding stopping valve, and the embolectomy device body is placed in the protecting sheath tube and pushed into the micro guide tube through the conveying wire. According to the blood-vessel embolectomy device with the helical structure and the thrombus treating apparatus, flexibility is good, the embolectomy device body can pass through the bent blood vessel or reach the blood vessel with the thin far end, and harm to the blood vessel wall is reduced to be minimum.

Description

A kind of taking thrombus device with helical structure and thrombus treating apparatus thereof
Technical field
The present invention relates to a kind of taking thrombus device with helical structure and use the thrombus treating apparatus of this device, specifically, particularly to a kind of medical apparatus and instruments getting involved blood vessel, for when acute ischemic stroke occurs, eliminating mechanically and be blocked in endovascular thrombosis to reach the Therapeutic Method of instant recovery blood flow, what be particularly suited for intracranial vessel takes bolt.
Background technology
Cerebral infarction is once occur, it is necessary within the shortest time, (effective time window) makes revascularization. At present, the Therapeutic Method of Intracranial thrombus mainly has two kinds: medicine thrombolytic and machinery take bolt.
Medicine thrombolytic is with thrombus by intravenous injection rt-PA (tissue-type plasminogen activator) or urokinase, it is possible to by intra-arterial contact thrombolysis, antiplatelet aggregation and anticoagulant treatment etc. Although thromboembolism treatment has been shown to improve preferably neurological outcome, but, according to US National sacred disease and apoplexy institute (TheNationalInstituteNeurologicalDisordersandStrokert-PAS trokeStudyGroup, NINDS) research is thought, intravenous thrombolysis should carry out within falling ill 3 hours, Arterial thrombolysis time window should within 6 hours, and the patient that so short thrombolytic time window causes only 4.5%-6.3% can accept thromboembolism treatment; Secondly, thromboembolism treatment is suitable only for the thrombosis of small volume, and the therapeutic effect of large volume thromboembolism is unsatisfactory; And, thrombolytic drug is had anaphylaxis by some patients, is not suitable for thromboembolism treatment.
In order to solve the problem of said medicine thrombolytic, for exceeding thrombolytic time window and not tolerating the patient of thromboembolism treatment, adopt machinery to take bolt and remove the thrombosis of blocking. In the prior art, it has been disclosed that machinery as described below takes pin device:
In the patent of invention that the patent No. is CN104000635A " take bolt device and take pin device " that China announces, have and multiple stretch into the cancellated intraluminal interior female rod with three-D profile, tube chamber is fixed at its two ends, in removal process after catching thrombosis, it is possible to by interior female rod fix blood bolt.
The patent of invention " for removing the device of thrombosis from blood vessel " that the patent No. disclosed in China is CN101340849A, by a caged or tubular structure, one distal member with the fiber extended radially out is taken in wherein, and safely eliminate thrombosis from Ink vessel transfusing under the help of fiber.
In the patent of invention " Intravascular Thrombus and embolus resectoscope " that the patent No. disclosed in China is CN101396295A; there is the thrombectomy device of a thrombectomby spring and the basket in contraction or release conditions; basket is positioned at the far-end of thrombectomy device; arrest thrombosis by the winding of thrombectomby spring, and take out to protect the far-end of blood vessel with basket together with thrombosis fragment by taking the clot of generation in bolt process.
In the patent of invention that the patent No. is CN102316809A " endovascular thrombosis grabber " that China announces, having the line main body haunted freely and be located at the thrombosis capture portion of its front end, the motion of the elastica circle body by being erected between fixed part and movable part removes, to catch, the thrombosis being attached to blood vessel wall.
In the patent of invention " device for removal of thromboses " that the patent No. disclosed in China is CN101035474A, there is the guide wire that a far-end is equipped with the fiber component of an orthohormbic structure, from body cavity and blood vessel, take out foreign body and thrombosis by the motion before and after it.
In the patent of invention that the patent No. is CN102014772A " method and apparatus for restoration of blood flow " that China announces, have a self expandable taper overlay structure by the cancellated parts of interconnective line or filament or pillar, by microtubular with push after wire is introduced into inaccessible blood vessel self expandable to recover blood flow.
In the patent of invention " for treating the system and method for cerebral infarction " that the patent No. disclosed in China is CN101027004A, there is guiding and occlusion catheter, conveying and draw catheter, lift suction pump, thromboembolic receiver and thromboembolic separator, lift suction pump passes through draw catheter by Biochemical analyzer to thromboembolic receiver, thus withdrawing from external.
In the utility model that the patent No. is ZL200620164685.4 " taking bolt device " of China's bulletin, there is the umbrella of the three-jaw short by two length one of elastic memory function, with periphery have net formed a circular configuration take pin device, by drawing push-pull bar to make three-jaw close up outward, thrombosis pocket is recovered in trocar sheath in umbrella portion, thrombosis is taken out.
In the patent of invention that the patent No. is US7931659B2 " SystemandMethodforTreatingIschemicStroke " of U.S. Publication, there is a receptor being surrounded into hollow tubular by many filaments being fixed on an elongated extension tube end, by extension tube, receptor is placed in blood vessel embolism position, and thrombosis taken in the intracavity of receptor hollow and takes out external.
In the patent of invention that the patent No. is US2006/0047286A1 " ClotRetrieverDevice " of U.S. Publication, there is one and be fixed on the expansible of pusher end and the recovery basket shunk, it has a tinsel that can pass through to be fixed on basket end control the uncovered in order to be caught in basket by thrombosis of opening and closing.
In the patent of invention that the patent No. is US2002/0049452A1 " ClotRetrieverDevice " of U.S. Publication, have one or more be fixed on slender conduit can in compression element movable have a shape memory take latch, after being transported to thromboembolism position by slender conduit, take in latch is flared out thrombosis is caught and is wrapped in.
In the patent of invention that the patent No. is US2009/0240238A1 " ClotRetrievalMechanism " of U.S. Publication, have one be fixed on a slender axles end can the snare of self-expanding and an attached to it folding sack being made up of flexible non-porous material, by slender axles, device is placed in thromboembolism position along internal passage, opens sack by thrombosis bag in the inner.
Various machineries described above take pin device, all there is open defect: when thrombosis cannot be looked at straight, the catching device of basket or web form tends not to entangle blood clot and causes taking bolt failure, and its volume is often excessive, cannot use in the cerebral arterieies such as thinner middle cerebral artery M1, M2 section of blood vessel diameter, when catching recovery after thrombosis, thrombosis is fixed insecure, it is easy to come off; Although although the pin device that takes having solves the problem of thrombus breaks loose, but its structure is complicated, the interior female rod structure for fixing thrombosis of increase makes the compliance taking pin device overall greatly reduce, so as to tortuous intracranial vessel can not be passed through.
On the other hand, although it is safe that the mode of existing negative pressure absorbing takes bolt, but only that relatively soft thromboembolism is effective by drawing removal; In order to strengthen drawing effect, adopt rotating blade or resectoscope fragmentation thrombosis, although this rotating blade feature improves the effect of this aspiration technique, but considerably increased the risk that blood vessel wall is caused damage; Although laser and ultrasound wave are cleaning and the effective energy, but such as misoperation, very easily peripheral vessels are caused damage, and energy is too low then invalid, too high then injured blood vessel, therefore it is difficult to determine that giving how high-octane laser intensity can be only achieved optimum curative effect.
Accordingly, it would be desirable to prior art is further improved, it is desirable to the intracranial vessel designing a kind of improvement takes bolt device, one, and volume should be sufficiently small, compliance should be enough good, so that device can enter the distal vessels that intracranial is thinner; Its two, capture rate is high, and thrombosis is grip good, fixation in taking bolt removal process, difficult drop-off; Its three, radially support force is little, and blood vessel wall and Peripheral Vascular Injuries is little.
Summary of the invention
The technical problem to be solved is in that, a kind of taking thrombus device with helical structure and thrombus treating apparatus thereof are provided, take bolt utensil and have the open architecture that helically formula rises, take during bolt the chucking power of thrombosis is sufficiently large, take thrombosis in bolt process and do not slip; Folding property is good, and compliance is high, takes bolt device and can pass through curved blood vessel or arrive the blood vessel that far-end is thinner; Radially support force is little, takes in bolt process and causes damage to be preferably minimized blood vessel wall and peripheral vessels.
The present invention is realized in, a kind of taking thrombus device with helical structure is provided, can be used for intracranial, cervical region, take bolt device and include being positioned at the developing ring of its near-end, its far-end development circle and be arranged on developing ring and development circle between take bolt device, described take webmaster shape or the cage structure that bolt device includes being made up of multiple unit grids being coupled to each other, each described unit grid by interconnective muscle around forming, this webmaster shape or cage structure can be collapsed folding under pressure and have self-expanding recovery capability in a free state, and, this webmaster shape or collapsing of cage structure fold and expand and can mutually change without difficulty, described netted or cage structure is open, and its side has axial clearance, and described axial clearance is along netted or cage structure outer surface spiral extension. this device can be used for human vas, and other adapts to position.
Further, described in take the unit grid of bolt device and be incremented by one by one in the vertical, described axial clearance) spiral helicine starting point and ending point axial-rotation one week.
Further, described in take bolt device unit grid each two in the vertical be incremented by, the spiral helicine starting point and ending point of described axial clearance is at axial-rotation half cycle.
Further, described in take the unit grid of bolt device in the vertical every three be incremented by, the spiral helicine starting point and ending point of described axial clearance was axial-rotation 1/4th weeks.
Further, described in take bolt device there is oblong shape or oblong shape under self-expanding state, its length range is between 5 millimeters to 60 millimeters, and its diameter range is between 2 millimeters to 6 millimeters.
Further, the ratio of the length of described unit grid and height is more than 1 and less than 2.
Further, the proximal end taking bolt device described under self-expanding state is arranged to pyramidal structure, its proximate expand gradually, and its tapering is 30 ° to 60 °.
Further, the surface-coated taking bolt device described in has the coating containing anticoagulant or antiplatelet drug.
Further, described developing ring and development circle all by can be visual under X ray material make.
Further, described developing ring and development circle are connected with taking bolt device by modes such as welding or crimp or be cementing.
Further, take bolt device described in be made up of shape-memory material.
The invention also discloses a kind of thrombus treating apparatus, employ the aforesaid taking thrombus device with helical structure, this therapeutic instrument also includes protection sheath pipe and conveying silk, and/or microtubular, and/or guiding catheter, the external diameter of described protection sheath pipe is less than the internal diameter of guiding catheter, the external diameter of described microtubular is less than the internal diameter of protection sheath pipe, described protection sheath pipe is placed in guiding catheter, described microtubular is placed in protection sheath pipe, the described bolt device that takes is placed in protection sheath pipe, or it is placed in microtubular, described conveying silk one end couples with the developing ring taking bolt device near-end, the conveying of described conveying silk takes bolt device.
Further, described conveying silk is made up of the soft tinsel with certain rigidity.
Further, described protection sheath pipe is made up of polymeric material.
Compared with prior art, taking thrombus device with helical structure and the thrombus treating apparatus thereof of the present invention provide the benefit that: can be greatly improved the chucking power to thrombosis by taking the design of bolt device spiral fold in the axial direction, make to take bolt device, whole taking, bolt process can be helically wrapped around whole thrombosis, greatly reduce the risk of thrombus breaks loose; And due to open design so that taking bolt device folding property good, overall compliance is enough good; Structurally, it does not have increase extra parts, this purpose can just be reached only by change shape, it is easy to processing.
Accompanying drawing explanation
Fig. 1 is the structural representation of the thrombus treating apparatus of the blood vessel with helical structure of the present invention;
The bolt device that takes that Fig. 2 is in Fig. 1 is accommodated in the viewgraph of cross-section protected in sheath pipe;
Fig. 3 is the schematic perspective view taking bolt device of the present invention;
Fig. 4 is the expansion schematic diagram taking bolt device first embodiment of Fig. 3, and wherein the spiral of unit grid is incremented by one by one;
Fig. 5 be Fig. 4 take the schematic perspective view that bolt device is under free state, the helical structure of its axial clearance rotates a circle;
Fig. 6 is the expansion schematic diagram taking bolt device the second embodiment of Fig. 3, and wherein the spiral each two of unit grid is incremented by;
Fig. 7 be Fig. 6 take the schematic perspective view that bolt device is under free state, the helical structure half revolution of its axial clearance;
Fig. 8 is the expansion schematic diagram taking bolt device the 3rd embodiment of Fig. 3, and wherein every three of the spiral of unit grid is incremented by;
Fig. 9 be Fig. 8 take the schematic perspective view that bolt device is under free state, the helical structure of its axial clearance rotates 1/4th weeks;
Figure 10 is the size relationship schematic diagram of the unit grid of Fig. 4.
Detailed description of the invention
In order to make the technical problem to be solved, technical scheme and beneficial effect clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated. Should be appreciated that specific embodiment described herein is only in order to explain the present invention, is not intended to limit the present invention.
In the terms of the present invention, " far-end " and " near-end " is appreciated that and observes from the direction of the doctor in charge. Far-end is remote from the side of the doctor in charge, and it relates to the parts of the apparatus of the present invention being advanced in vascular system further, and near-end represents towards the doctor in charge, i.e. it is not far that the nearside arrangement component of this device is introduced in blood vessel.
In the present invention, if phrase " longitudinal direction " is with in this document, it is to be understood as the direction representing that apparatus of the present invention are pushed into, and the longitudinal axis of this device also overlaps along the longitudinal axis of its blood vessel moved forward with this device. It is defined as axially with longitudinally perpendicular direction.
Shown in Fig. 1 and Fig. 3, a kind of taking thrombus device with helical structure of the present invention, including taking bolt device 100, being positioned at the developing ring 300 taking bolt device 100 near-end and be positioned at the development circle 200 taking bolt device 100 far-end. Take webmaster shape or cage structure that bolt device 100 includes being made up of multiple unit grids 170 being coupled to each other, each unit grid 170 by interconnective muscle 120 around forming. This webmaster shape or cage structure can be collapsed folding under pressure and have self-expanding recovery capability in a free state, and, this webmaster shape or collapsing of cage structure fold and expand and can mutually change without difficulty.
Netted or cage structure is open, and its side has axial clearance 160, and axial clearance 160 is along netted or cage structure outer surface spiral extension. Open be interpreted as unit grid 170 be interconnected to do not close, there are webmaster shape or the cage structure of open axial clearance 160 in its side, this axial clearance 160 has at least a place, it is possible to design has many places. The axial clearance 160 embodiment design of the present invention is a place, as shown in Fig. 5, Fig. 7 and Fig. 9. With this structure, take bolt device 100 and can fold easily in thinner blood vessel, and due to fold plane twist, its chucking power clamping thrombosis will be greatly improved, and effectively prevent thrombus breaks loose from flowing to the blood vessel that far-end is more tiny.
The helicoidal structure of the axial clearance 160 taking bolt device 100 has numerous embodiments, The present invention gives following several embodiment:
Embodiment one, as shown in Figures 3 to 5: the unit grid 170 taking bolt device 100 is incremented by the vertical one by one, the spiral helicine starting point and ending point of axial clearance 160 was axial-rotation one week. What this allowed for taking bolt device 100 circumferentially any point is folded into possibility, say, that takes the bolt device 100 folding clamping to thrombosis around whole circumference, is nonlinear, the clamping dynamics of thrombosis will be greatly improved.
Embodiment two, as shown in Fig. 6 and Fig. 7: unit grid 170 each two in the vertical taking bolt device 100 is incremented by, and the spiral helicine starting point and ending point of axial clearance 160 is at axial-rotation half cycle. The advantage of this spline structure is, both ensure that taking bolt device 100 is clamped on semi-circumference helix to the folding of thrombosis, also can make to take the pliability that bolt device 100 keeps certain, be unlikely to cave in the progradation taking bolt device 100.
Embodiment three, as shown in FIG. 8 and 9: take the unit grid 170 of bolt device 100 in the vertical every three be incremented by, the spiral helicine starting point and ending point of axial clearance 160 was axial-rotation 1/4th weeks.Such structure can make to take bolt device 100 and limitedly fold on axial screw line, has certain radial direction support force while ensureing thrombosis is clamped.
The near-end taking bolt device 100 is arranged to pyramidal structure 130, proximate expand gradually, and its tapering is 30 ° to 60 °. The advantage of this design is can greatly to reduce propelling resistance when taking bolt device and reclaiming into guiding catheter.
Taking bolt device 100 and have oblong shape or oblong shape under self-expanding state, its length range is between 5 millimeters to 60 millimeters, and its diameter range is between 2 millimeters to 6 millimeters, to adapt to the anatomical structure of patient's intracranial vessel.
Refer to shown in Figure 10, the ratio of the length L1 of unit grid 170 and height H1, more than 1 and less than 2, is similar to diamond structure, and the advantage of this structure is easy to deformation, taking bolt device self-expanding expansion and retraction can be readily accomplished when subsiding folding.
The surface-coated taking bolt device 100 has the coating containing anticoagulant or antiplatelet drug, to strengthen the mobility of blood, it is simple to take pushing of bolt device.
Developing ring 300 and development circle 200 all by can be visual under X ray material make, it is preferable that for platinum, platinoiridita, platinum-tungsten alloys, gold, silver etc. The not transmission X-ray label of the type adds to be located at and takes bolt device 100 proximally and distally so that the doctor in charge can monitor by imaging device location relative to each other and therapeutic advance thus improve the accuracy taking bolt. Being connected to the label developing ring with not transmission X-ray taking bolt device two ends and development circle, making to take bolt device can operate visually under the support of digital subtraction angiography system, and makes to take bolt accurately and reliably. Doctor only advances and withdraws this device and just can complete to take bolt operation, with traditional take bolt operation compared with, operation process is greatly simplified, and has both alleviated the workload of doctor, get again the treatment time of preciousness for patient, strive for the more time for reversible ischemic tissue of brain.
Developing ring 300 and development circle 200 are connected with taking bolt device 100 by modes such as welding or crimp or be cementing. This connection should reach certain intensity, it is prevented that takes bolt device and comes off in taking bolt process.
Take bolt device 100 to be made up of shape-memory material. The shape-memory material of indication of the present invention refer in particular to generation be NiTi evanohm. Taking bolt device 100 is adopt NiTi evanohm to make via cut.
Shown in Fig. 1 and Fig. 2; the invention also discloses a kind of thrombus treating apparatus; employ the above-mentioned taking thrombus device with helical structure; this therapeutic instrument also includes protection sheath pipe 400, conveying silk 500, microtubular 600, guiding catheter (not shown) and rotates haemostatic valve (not shown), and the external diameter of microtubular 600 is less than the internal diameter of guiding catheter. Microtubular 600 is pushed to blood embolization place along guiding catheter in guiding catheter; protection sheath pipe 400 is interconnected with microtubular 600 by rotating haemostatic valve; take bolt device 100 and be placed in protection sheath pipe 400, conveying silk 500 be pushed in microtubular 600, and be pushed to blood embolization place. Guiding catheter has ratio for placing protection sheath pipe 400 and the bigger internal diameter of microtubular 600. So, whole thrombosis and be in the bolt device 100 that takes of its swelling state and can move and be placed in guiding catheter. During treating, microtubular 600 is also advanced to usually by guiding catheter, although guiding catheter can be pushed ahead until blood embolization position, but in the blood vessel that inner chamber is little especially, especially in intracranial area, only with the microtubular 600 that diameter is only small, take bolt device 100 and be placed in microtubular 600 and be transported to the enforcement of blood embolization position take bolt operation.
Conveying silk 500 is made up of the soft tinsel with certain rigidity. Should be appreciated that to expect purpose, the far-end of conveying silk 500; especially into intracranial vessel section, it is necessary to have enough rigidity, but simultaneously must be sufficiently flexible or flexible; make them can pass protection sheath pipe 400 or guiding catheter, and be damaged from blood vessel wall. Its length dimension should ensure that and will take pin device and be delivered to the position of thromboembolism. Protection sheath pipe 400 is made up of polymeric material. This polymeric material is politef. The internal diameter of protection sheath pipe 400 and length dimension should ensure that and the soft taking bolt device 100 and conveying silk 500 far-end is held protection wherein.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all any amendment, equivalent replacement and improvement etc. made within the spirit and principles in the present invention, should be included within protection scope of the present invention.

Claims (14)

1. the taking thrombus device with helical structure, the described bolt device (100) that takes includes being positioned at the developing ring (300) of its near-end, be positioned at its far-end development circle (200) and be arranged on developing ring (300) and development circle (200) between take bolt device (100), it is characterized in that, described take webmaster shape or the cage structure that bolt device (100) includes being made up of multiple unit grids (170) being coupled to each other, one or more described unit grids (170) and other adjacent cells grid (170) are formed by connecting, this webmaster shape or cage structure can be collapsed folding under pressure and have self-expanding recovery capability in a free state, and, this webmaster shape or collapsing of cage structure fold and expand and can mutually change, described netted or cage structure is open, and its side has axial clearance (160), and described axial clearance (160) are along netted or cage structure outer surface spiral extension.
2. the taking thrombus device with helical structure as claimed in claim 1, it is characterized in that, the described unit (170) taking bolt device (100) is incremented by the vertical one by one, and the spiral helicine starting point and ending point of described axial clearance (160) was axial-rotation one week.
3. the taking thrombus device with helical structure as claimed in claim 1, it is characterized in that, described unit grid (170) each two in the vertical taking bolt device (100) is incremented by, and the spiral helicine starting point and ending point of described axial clearance (160) is at axial-rotation half cycle.
4. the taking thrombus device with helical structure as claimed in claim 1, it is characterized in that, the described unit grid (170) taking bolt device (100) in the vertical every three be incremented by, the spiral helicine starting point and ending point of described axial clearance (160) was axial-rotation 1/4th weeks.
5. the taking thrombus device with helical structure as described in any one in Claims 1-4, it is characterized in that, the described bolt device (100) that takes has oblong shape or oblong shape under self-expanding state, its length range is between 5 millimeters to 60 millimeters, and its diameter range is between 2 millimeters to 6 millimeters.
6. the taking thrombus device with helical structure as claimed in claim 5, it is characterised in that the length (L1) of described unit grid (170) and the ratio of height (H1) are more than 1 and less than 2.
7. the taking thrombus device with helical structure as claimed in claim 5, it is characterized in that, the proximal end taking bolt device (100) described under self-expanding state is arranged to pyramidal structure (130), its proximate expand gradually, and its tapering is 30 ° to 60 °.
8. the taking thrombus device with helical structure as claimed in claim 5, it is characterised in that described in take the surface-coated of bolt device (100) and have the coating containing anticoagulant or antiplatelet drug.
9. the taking thrombus device with helical structure as claimed in claim 5, it is characterised in that described developing ring (300) and development enclose (200) all by can be visual under X ray material make.
10. the taking thrombus device with helical structure as claimed in claim 9, it is characterised in that described developing ring (300) and development circle (200) are connected with taking bolt device (100) by modes such as welding or crimp or be cementing.
11. the taking thrombus device with helical structure as claimed in claim 5, it is characterised in that described in take bolt device (100) and be made up of shape-memory material.
12. a thrombus treating apparatus, it is characterized in that, employ the taking thrombus device with helical structure as described in any one in Claims 1-4, this therapeutic instrument also includes protection sheath pipe (400) conveying silk (500), microtubular (600), guiding catheter and rotation haemostatic valve, the external diameter of described microtubular (600) is less than the internal diameter of guiding catheter, described microtubular (600) is pushed to blood embolization place along guiding catheter in guiding catheter, described protection sheath pipe (400) is interconnected with microtubular (600) by rotating haemostatic valve, the described bolt device (100) that takes is placed in protection sheath pipe (400), it is pushed in microtubular (600) by described conveying silk (500), and it is pushed to blood embolization place.
13. thrombus treating apparatus as claimed in claim 12, it is characterised in that described conveying silk (500) is made up of the soft tinsel with certain rigidity.
14. thrombus treating apparatus as claimed in claim 12, it is characterised in that described protection sheath pipe (400) is made up of polymeric material.
CN201610009736.4A 2016-01-06 2016-01-06 Blood vessel thrombus taking device with spiral structure and thrombus therapeutic instrument thereof Active CN105662533B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610009736.4A CN105662533B (en) 2016-01-06 2016-01-06 Blood vessel thrombus taking device with spiral structure and thrombus therapeutic instrument thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610009736.4A CN105662533B (en) 2016-01-06 2016-01-06 Blood vessel thrombus taking device with spiral structure and thrombus therapeutic instrument thereof

Publications (2)

Publication Number Publication Date
CN105662533A true CN105662533A (en) 2016-06-15
CN105662533B CN105662533B (en) 2020-09-04

Family

ID=56299393

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610009736.4A Active CN105662533B (en) 2016-01-06 2016-01-06 Blood vessel thrombus taking device with spiral structure and thrombus therapeutic instrument thereof

Country Status (1)

Country Link
CN (1) CN105662533B (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106580397A (en) * 2016-12-20 2017-04-26 北京久事神康医疗科技有限公司 Sectional thrombus extraction device and thrombus extraction method making use of thrombus extraction device
CN106620974A (en) * 2016-08-26 2017-05-10 中国人民解放军军事医学科学院野战输血研究所 Electrically controlled pneumatic tissue repairing and spraying device method
CN107049421A (en) * 2017-05-09 2017-08-18 心凯诺医疗科技(上海)有限公司 A kind of full development takes bolt support and thrombus withdrawing device
CN107137125A (en) * 2017-06-20 2017-09-08 微创神通医疗科技(上海)有限公司 Take bolt support and take pin device
CN107212913A (en) * 2017-04-30 2017-09-29 沈阳新智源医疗用品有限公司 A kind of support with thrombus capturing means takes bolt device
CN109350181A (en) * 2018-11-21 2019-02-19 中国医科大学 A kind of taking thrombus device
CN109965941A (en) * 2017-12-28 2019-07-05 先健科技(深圳)有限公司 One kind taking bolt device
CN111053594A (en) * 2018-10-17 2020-04-24 先健科技(深圳)有限公司 Thrombus taking device
CN112842466A (en) * 2020-12-30 2021-05-28 杭州亿科医疗科技有限公司 Thrombus-taking support
CN113116455A (en) * 2019-12-31 2021-07-16 辽宁垠艺生物科技股份有限公司 High-support high-compliance net pipe structure

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514273B1 (en) * 2000-03-22 2003-02-04 Endovascular Technologies, Inc. Device for removal of thrombus through physiological adhesion
US20050267491A1 (en) * 2003-04-02 2005-12-01 James Kellett Embolectomy devices
CN102596098A (en) * 2009-07-08 2012-07-18 同心医疗公司 Vascular and bodily duct treatment devices and methods
CN203379185U (en) * 2013-06-04 2014-01-08 加奇生物科技(上海)有限公司 Intracranial thrombus removing device
CN103547224A (en) * 2011-05-13 2014-01-29 菲诺克斯有限公司 Thrombectomy device
CN205359560U (en) * 2016-01-06 2016-07-06 赵烜 Blood vessel thrombectomy device and thrombus therapeutic instrument with helical structure

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514273B1 (en) * 2000-03-22 2003-02-04 Endovascular Technologies, Inc. Device for removal of thrombus through physiological adhesion
US20050267491A1 (en) * 2003-04-02 2005-12-01 James Kellett Embolectomy devices
CN102596098A (en) * 2009-07-08 2012-07-18 同心医疗公司 Vascular and bodily duct treatment devices and methods
CN103547224A (en) * 2011-05-13 2014-01-29 菲诺克斯有限公司 Thrombectomy device
CN203379185U (en) * 2013-06-04 2014-01-08 加奇生物科技(上海)有限公司 Intracranial thrombus removing device
CN205359560U (en) * 2016-01-06 2016-07-06 赵烜 Blood vessel thrombectomy device and thrombus therapeutic instrument with helical structure

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620974A (en) * 2016-08-26 2017-05-10 中国人民解放军军事医学科学院野战输血研究所 Electrically controlled pneumatic tissue repairing and spraying device method
CN106580397A (en) * 2016-12-20 2017-04-26 北京久事神康医疗科技有限公司 Sectional thrombus extraction device and thrombus extraction method making use of thrombus extraction device
CN107212913A (en) * 2017-04-30 2017-09-29 沈阳新智源医疗用品有限公司 A kind of support with thrombus capturing means takes bolt device
CN107049421A (en) * 2017-05-09 2017-08-18 心凯诺医疗科技(上海)有限公司 A kind of full development takes bolt support and thrombus withdrawing device
CN107049421B (en) * 2017-05-09 2023-11-17 心凯诺医疗科技(上海)有限公司 Full-development thrombus taking support and thrombus taking device
CN107137125B (en) * 2017-06-20 2023-08-04 微创神通医疗科技(上海)有限公司 Bolt taking support and bolt taking device
CN107137125A (en) * 2017-06-20 2017-09-08 微创神通医疗科技(上海)有限公司 Take bolt support and take pin device
CN109965941A (en) * 2017-12-28 2019-07-05 先健科技(深圳)有限公司 One kind taking bolt device
CN109965941B (en) * 2017-12-28 2022-09-09 先健科技(深圳)有限公司 Thrombus taking device
CN111053594B (en) * 2018-10-17 2022-06-21 先健科技(深圳)有限公司 Thrombus taking device
CN111053594A (en) * 2018-10-17 2020-04-24 先健科技(深圳)有限公司 Thrombus taking device
CN109350181A (en) * 2018-11-21 2019-02-19 中国医科大学 A kind of taking thrombus device
CN113116455A (en) * 2019-12-31 2021-07-16 辽宁垠艺生物科技股份有限公司 High-support high-compliance net pipe structure
CN113116455B (en) * 2019-12-31 2023-10-24 辽宁垠艺生物科技股份有限公司 High-support Gao Roushun network management structure
CN112842466A (en) * 2020-12-30 2021-05-28 杭州亿科医疗科技有限公司 Thrombus-taking support

Also Published As

Publication number Publication date
CN105662533B (en) 2020-09-04

Similar Documents

Publication Publication Date Title
CN205359559U (en) Blood vessel thrombectomy device and thrombus therapeutic instrument with semi -closed structure
CN105662532A (en) Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same
CN105662533A (en) Blood-vessel embolectomy device with helical structure and thrombus treating apparatus with the same
CN105662534A (en) Blood vessel thrombus-taking device with spine-shaped structures and thrombus therapeutic instrument thereof
CN106618676B (en) Intravascular thrombus taking-out device
CN205359560U (en) Blood vessel thrombectomy device and thrombus therapeutic instrument with helical structure
CN103284775B (en) Encephalic thrombosis removing device
CN111904675B (en) Thrombus taking support and thrombus capturing device
JP5914432B2 (en) Recovery system and method of use
CN203379185U (en) Intracranial thrombus removing device
CN216125035U (en) Novel vein thrombus taking catheter
CN205339057U (en) Blood vessel thrombectomy device and thrombus therapeutic instrument with thorn column structure
CN110420046B (en) Minimally invasive interventional thrombus extraction instrument, application and use method thereof
CN213641088U (en) Intravascular thrombus capture device
CN105455878A (en) Catching device
CN111053594B (en) Thrombus taking device
CN115737059A (en) Spiral type non-cutting bolt taking device
US20160089227A1 (en) Clot and foreign body retrieval system and method for use
CN206675575U (en) A kind of Intravascular Thrombus withdrawing device
WO2022100734A1 (en) Thrombus-taking stent, thrombus-taking device and thrombus-taking system
CN104068911A (en) Blood vessel thrombus extracting implement and thrombus extracting device
CN115590578A (en) But distal end reducing suction device and system
WO2021180550A1 (en) Snare for removal of implanted cardiac leads
CN217338724U (en) Vascular opening device
CN218247309U (en) But distal end reducing suction device and system

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20160711

Address after: 519000, building sixth, room 603, room 10, main building, No. 1, science and technology road, Harbour Road, Tang Wan Town, Guangdong, Zhuhai,

Applicant after: Zhuhai trans Bridge Medical Technology Co., Ltd.

Address before: 311121, No. 1, 18 science Avenue, Yuhang street, Yuhang District, Zhejiang, Hangzhou

Applicant before: Zhao Hui

CB03 Change of inventor or designer information

Inventor after: Zhao Zhong

Inventor before: Zhao Zhong

Inventor before: Chen Zhigang

Inventor before: Xu Bingke

Inventor before: Shi Lei

COR Change of bibliographic data
GR01 Patent grant
GR01 Patent grant