CN1063820A - The manufacture method of tinea unguium dissolving cream - Google Patents

The manufacture method of tinea unguium dissolving cream Download PDF

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Publication number
CN1063820A
CN1063820A CN 91100678 CN91100678A CN1063820A CN 1063820 A CN1063820 A CN 1063820A CN 91100678 CN91100678 CN 91100678 CN 91100678 A CN91100678 A CN 91100678A CN 1063820 A CN1063820 A CN 1063820A
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China
Prior art keywords
medicine
tinea unguium
manufacture method
patient
ointment
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Pending
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CN 91100678
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Chinese (zh)
Inventor
郭义
樊芝芹
郭冬梅
郭铁男
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Individual
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Individual
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Priority to CN 91100678 priority Critical patent/CN1063820A/en
Publication of CN1063820A publication Critical patent/CN1063820A/en
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Abstract

The manufacture method of tinea unguium dissolving cream belongs to field of medicine producing technology.Mainly adopt griseofulvin for oral administration and package to dial two kinds of method treatments of first to tinea unguium at present, griseofulvin for oral administration all has untoward reaction and side effect to Most patients, and it is also totally unfavorable to the patient that package is dialled the first art.It is easy to use to the invention provides a kind of patient, patient body is had no side effect and untoward reaction, after the application at short notice first fall the manufacture method that disease is removed ointment.This ointment is made up of seven flavor vegetalitas Chinese medicines, oxybenzoic acid Western medicine and other ten kinds of materials such as nine flavor mineral Chinese medicines, white Rhodiola dumulosa (Franch.) S.H.Fu such as Plumbum preparatium.

Description

The manufacture method of tinea unguium dissolving cream
The manufacture method of tinea unguium dissolving cream belongs to field of medicine producing technology.
The sick tinea unguium of treatment superficial fungi mainly is that griseofulvin for oral administration and package are dialled two kinds of Therapeutic Method of first at present.Griseofulvin for oral administration all has untoward reaction to Most patients, and side effect is big, and is difficult for for a long time proving effective.Package is dialled first requirements of operation patient and must be arrived specialist hospital and carry out, and this is very inconvenient to old person, and the patient who has simultaneously sees that to dial the first operation forbidding, is reluctant to accept this kind therapy.As for vast ungetable outlying district patient, more be unfavorable for treatment.
Purpose of the present invention: provide a kind of patient to carry, convenient at any time the use has no side effect to patient body, has no adverse reaction, and sick first cutin is had strong dissolution, and first is fallen the manufacture method that disease is removed ointment at short notice.
Content of the present invention: the composition and the percentage by weight of tinea unguium dissolving cream are as follows:
One, mineral Chinese medicine:
Plumbum preparatium 3-5%, Melanteritum 2-5%, Alumen 3-5%, Sublimed Sulfur 2-4%, dried Alumen 2-4%, Gypsum Fibrosum preparata 2-4%, Orpimentum (Auripigmentum) 2-4%, Aerugo 2-4%, Cinnabaris 1-3%.
Two, vegetalitas Chinese medicine:
Cattle lice ghost 3-5%, yellow one hundred 3-5%, white Rhodiola dumulosa (Franch.) S.H.Fu 3-5%, Rhizoma Typhonii 2-4%, Cortex Dictamni 2-4%, Radix Angelicae Dahuricae 2-4%, side BAIYE 2-4%.
Three, Arabic medicine:
Olibanum 0.5-4%, Myrrha 0.5-4%.
Four, Western medicine and other:
Carbonyl diamine 30-50%, lactic acid 1-2%, benzoic acid 0.1-0.2%, oxybenzoic acid 5-10%, lanoline 15-40%, vaseline 3-10%, Cera Flava 5-15%, mineral tallow 5-15%.
Good effect of the present invention: the dissolving cream that adopts this method to make, to obvious curative effects all being arranged at the commonly encountered diseases of the vast warm humid area of China and Asia, Africa and Latin America, the tinea unguium or the tinea unguium of frequently-occurring disease superficial fungi disease.Fungus trichophyton, trichophyton gypseum and acrothesium floccosum for infringement fingernail or toenail all have the obvious suppression effect.For the fingernail or the toenail cutin that are subjected to above fungus infringement intensive dissolution is arranged all.The ointment that adopts this method to make, medicine is changed in the general each application of patient 48 hours two to four times, just can reach first and fall the effect that disease is removed.The ointment that adopts this method to make is easy to use, and the patient is had no side effect, and has no adverse reaction, and effective percentage reaches 100%.
Embodiment one:
The composition and the percentage by weight of present embodiment tinea unguium dissolving cream are as follows:
Plumbum preparatium 3%, Melanteritum 2%, distillation dredge 2%, dried Alumen 2%, Olibanum 0.5%, Myrrha 0.5%, carbonyl diamine 42%, oxybenzoic acid 6%, lanoline 22%, vaseline 4%, Cera Flava 8%, mineral tallow 8%.Above Chinese medicine, Arabic medicated powder are broken into the end, carbonyl diamine, oxybenzoic acid also are ground into fine flour, Cera Flava, mineral tallow, lanoline, vaseline are placed in the dissolving tank dissolve again with immersion method.Then, the powder of Chinese medicine, Arabic medicine is put into dissolving tank stir, again the fine flour of carbonyl diamine, oxybenzoic acid is also put into dissolving tank and stir, treat that evenly the back bottling has been a patent medicine.
Cure example: the man, 30 years old, left hand thumb, forefinger, middle finger all infected tinea unguium, and the Second Academy of medical university is diagnosed as tinea unguium through Harbin, medical history 8 years.With the ointment treatment middle finger that the present embodiment method is made, fully recover.The fingernail that newly grows is ruddy glossy, and the tinea unguium of thumb and forefinger does not heal so far with the other medicines treatment.
Embodiment two:
The composition and the percentage by weight of present embodiment tinea unguium dissolving cream are as follows:
White Rhodiola dumulosa (Franch.) S.H.Fu 3%, Rhizoma Typhonii 3%, favus skin 2%, the Radix Angelicae Dahuricae 2%, carbonyl diamine 42%, oxybenzoic acid 6%, lanoline 20%, vaseline 6%, Cera Flava 8%, mineral tallow 8%.Manufacturing process is identical with embodiment one.
Cure example: the woman, 45 years old, year surplus the toenail of left foot thumb and right crus of diaphragm thumb all ill ten, be diagnosed as tinea unguium through Heilongjiang Provincial Hospital, behind the ointment that application present embodiment method is made, sick first is all taken off, and the toenail that newly grows with all the other not sick toenails invariably together, white touched with red, glossy.
Embodiment three:
The composition and the percentage by weight of present embodiment tinea unguium dissolving cream are as follows:
White Rhodiola dumulosa (Franch.) S.H.Fu 3%, Plumbum preparatium 3%, Melanteritum 2%, Rhizoma Typhonii 2%, carbonyl diamine 42%, oxybenzoic acid 6%, lanoline 20%, vaseline 6%, Cera Flava 8%, mineral tallow 8%.Manufacturing process is identical with embodiment one.
Cure example: the man, 33 years old, the left hand thumb was suffered from fingernail sick 7 years, was diagnosed as tinea unguium through Heilongjiang Province institute of internal medicine, and griseofulvin for oral administration does not take effect more than a year, and the dizzy sensation of feeling sick is arranged when period in a medicine.The doctor desires to do and pulls out first operation, and the patient fears, the refusal operation.The ointment that application present embodiment method is made three times applied 48 hours at every turn, and sick first is taken off.The deck that newly grows is hard glossy, with other not sick fingernail indifferences.

Claims (1)

1, the manufacture method of tinea unguium dissolving cream belongs to field of medicine producing technology, it is characterized in that its composition and percentage by weight are as follows:
A, mineral Chinese medicine: Plumbum preparatium 3-5%, Melanteritum 2-5%, Alumen 3-5%, Sublimed Sulfur 2-4%, dried Alumen 2-4%, Gypsum Fibrosum preparata 2-4%, Orpimentum (Auripigmentum) 2-4%, Aerugo 2-4%, Cinnabaris 1-3%;
B, vegetalitas Chinese medicine: cattle lice ghost 3-5%, yellow one hundred 3-5%, white Rhodiola dumulosa (Franch.) S.H.Fu 3-5%, Rhizoma Typhonii 2-4%, Radix Angelicae Dahuricae 2-4%, side BAIYE 2-4%;
C, Arabic medicine: Olibanum 0.5-4%, Myrrha 0.5-4%;
D, Western medicine and other: carbonyl diamine 30-50%, lactic acid 1-2%, the sour 0.1-0.2% that rests in peace, oxybenzoic acid 5-10%, lanoline 15-40%, vaseline 3-10%, Cera Flava 5-15%, mineral tallow 5-15%.
CN 91100678 1991-01-30 1991-01-30 The manufacture method of tinea unguium dissolving cream Pending CN1063820A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 91100678 CN1063820A (en) 1991-01-30 1991-01-30 The manufacture method of tinea unguium dissolving cream

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 91100678 CN1063820A (en) 1991-01-30 1991-01-30 The manufacture method of tinea unguium dissolving cream

Publications (1)

Publication Number Publication Date
CN1063820A true CN1063820A (en) 1992-08-26

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CN 91100678 Pending CN1063820A (en) 1991-01-30 1991-01-30 The manufacture method of tinea unguium dissolving cream

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994008591A1 (en) * 1992-10-15 1994-04-28 Schering-Plough Healthcare Products, Inc. Treatment for onychomycosis topically applying salicylic acid, optionally in combination with a retinoid
CN1063631C (en) * 1994-03-23 2001-03-28 华西医科大学附属第一医院 Lactic acid ointment
CN1090961C (en) * 1999-05-19 2002-09-18 成都新蓉灰指甲研究所 Process for preparing onychomycosis ointment
FR2844197A1 (en) * 2002-09-05 2004-03-12 Galderma Res & Dev Pharmaceutical or cosmetic solution for ungual or peri-ungual application, e.g. antifungal nail varnish, comprising synergistic pro-penetrant mixture of urea, acid and/or ethoxydiglycol
WO2004021968A3 (en) * 2002-09-05 2004-05-27 Galderma Res & Dev Solution for ungual application
CN100404062C (en) * 2006-05-22 2008-07-23 胡德洪 Powder for treating beriberi and preparation method thereof
CN102526567A (en) * 2011-12-23 2012-07-04 成美余 Ointment and medicine composite formula for removing tinea unguium and preparation method thereof

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994008591A1 (en) * 1992-10-15 1994-04-28 Schering-Plough Healthcare Products, Inc. Treatment for onychomycosis topically applying salicylic acid, optionally in combination with a retinoid
US5464610A (en) * 1992-10-15 1995-11-07 Schering-Plough Healthcare Products, Inc. Method for treating onychomycosis
CN1063631C (en) * 1994-03-23 2001-03-28 华西医科大学附属第一医院 Lactic acid ointment
CN1090961C (en) * 1999-05-19 2002-09-18 成都新蓉灰指甲研究所 Process for preparing onychomycosis ointment
FR2844197A1 (en) * 2002-09-05 2004-03-12 Galderma Res & Dev Pharmaceutical or cosmetic solution for ungual or peri-ungual application, e.g. antifungal nail varnish, comprising synergistic pro-penetrant mixture of urea, acid and/or ethoxydiglycol
WO2004021968A3 (en) * 2002-09-05 2004-05-27 Galderma Res & Dev Solution for ungual application
CN100404062C (en) * 2006-05-22 2008-07-23 胡德洪 Powder for treating beriberi and preparation method thereof
CN102526567A (en) * 2011-12-23 2012-07-04 成美余 Ointment and medicine composite formula for removing tinea unguium and preparation method thereof
CN102526567B (en) * 2011-12-23 2014-01-22 成美余 Ointment and medicine composite formula for removing tinea unguium and preparation method thereof

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