CN1156047A - Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method - Google Patents

Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method Download PDF

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Publication number
CN1156047A
CN1156047A CN 96115634 CN96115634A CN1156047A CN 1156047 A CN1156047 A CN 1156047A CN 96115634 CN96115634 CN 96115634 CN 96115634 A CN96115634 A CN 96115634A CN 1156047 A CN1156047 A CN 1156047A
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China
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filter
heart disease
coronary heart
gram
hours
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CN 96115634
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CN1053374C (en
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张玲
姚乾元
于宗渊
时延增
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SHANDONG PROV INST OF TRADITIONAL CHINESE MEDICINE
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SHANDONG PROV INST OF TRADITIONAL CHINESE MEDICINE
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Priority to CN96115634A priority Critical patent/CN1053374C/en
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Abstract

An oral liquid for curing coronary heart disease and angina pectoris with total effective rate of 93.6%, as well as thoracalgia, carbiopalmus, palpitation, etc. with totale ffective rate up to 86% or more is prepared from red sage root, tree peony bark andhoney. It also has the function of lowering blood pressure.

Description

A kind of treatment coronary heart disease, anginal Chinese medicine oral liquid and preparation method
The invention belongs to a kind of Chinese medicine preparation, especially treat coronary heart disease and anginal SHUANGDAN KOUFUYE.
At present, coronary heart disease, angina pectoris are commonly encountered diseases, frequently-occurring disease clinically, and sickness rate rises year by year, are the principal diseases that threatens human body health, traditional Chinese medicine in treatment based on blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain etc.At present treatment coronary heart disease, anginal Chinese patent medicine are more, but prescription is big, and flavour of a drug are many, and curative effect is not fairly obvious.
The purpose of this invention is to provide a kind of treatment coronary heart disease, anginal quick-acting, Chinese medicine oral liquid efficiently.The present invention utilizes Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, and the relieving restlessness that clears away heart-fire is aided with the effect of Cortex Moutan clearing away heat and cooling blood, hypertensive tranquilizing.Pharmacodynamics shows that the present invention can obviously prolong the mice normal pressure anoxia enduring time-to-live, but the ischemic ECG change due to the antagonism pituitrin; Can significantly reduce the myocardial infarction area that ligation heart branch of coronary artery is caused, the myocardium weight of infarct is obviously reduced; And the remarkable microcirculation disturbance that caused of antagonism pituitrin, and hypotensive effect is preferably arranged.
SHUANGDAN KOUFUYE of the present invention and preparation method thereof: it is characterized in that producing 1000 milliliters of SHUANGDAN KOUFUYE, required pharmaceutical formulation contains Radix Salviae Miltiorrhizae 550-650 gram, Cortex Moutan 250-350 gram, Mel 130-170 gram, sodium benzoate 2-3 gram.Process for preparing medicine: after Cortex Moutan distilled paeonol, medicinal residues and Radix Salviae Miltiorrhizae decocted with water secondary together, and 2 hours for the first time, 1 hour for the second time, to filter, filtrate concentrates, and concentrated solution adds ethanol makes pure content reach 60%, cold preservation (2-2 ℃) 24 hours; Filter, reclaim ethanol to most; Filter, add water-cooled and hid (2-2 ℃) 48 hours; Filter, add the Cortex Moutan distillate, add Mel, sodium benzoate, fill, sterilization.
Using method of the present invention: every day secondary, each 20 milliliters, 28 days is a course of treatment, takes for a long time, has no side effect.
Characteristics of the present invention and effect are: SHUANGDAN KOUFUYE of the present invention has the effect of blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain.Clinically cure mainly coronary heart disease due to the stagnation of heart-blood, angina pectoris, and good hypotensive effect is arranged.Show through three tame hospital clinical observed results, SHUANGDAN KOUFUYE treatment coronary heart disease total effective rate of the present invention is 93.6%, clinical obvious effective rate is 49.6%, to anginal total effective rate is 91.8%, clinical obvious effective rate is 45.9%, to the Electrocardiographic total effective rate of ischemic is 55.6%, clinical obvious effective rate is 17.8%, and can obviously improve thoracic obstruction blood stasis type patient's hemorheology whole blood viscosity, plasma viscosity, many indexs such as packed cell volume, to improving the every disease of the thoracic obstruction, chest pain, uncomfortable in chest, cardiopalmus, shortness of breath and fatigue, total effective rates such as die Blausucht reach more than 86%, in the clinical observation process, do not see untoward reaction, safe in utilization, be a kind of good curing coronary heart disease, anginal new drug.
Embodiment:
Get Radix Salviae Miltiorrhizae 550 grams, Cortex Moutan 250 grams place Cortex Moutan in the extraction pot, the water that adds 10 times, vapor distillation, distillate device are in addition placed, medicinal residues and Radix Salviae Miltiorrhizae decoct with water secondary, 2 hours for the first time, 1 hour for the second time, filter, filtrate concentrates, concentrated solution adds ethanol, makes pure content reach 60%, Cryoprecipitation jar Cryoprecipitation 24 hours (2-2 ℃); Filter, reclaim ethanol to most; Add the entry water precipitating 48 hours (2-2 ℃); Filter, add the Cortex Moutan distillate, add Mel 150 grams, sodium benzoate 3 grams, add water to 1000 milliliters, stir evenly, fill, sterilization, SHUANGDAN KOUFUYE of the present invention.

Claims (1)

1, a kind of treatment coronary heart disease and anginal SHUANGDAN KOUFUYE is characterized in that producing 100 milliliters of SHUANGDAN KOUFUYE, and required pharmaceutical formulation contains Radix Salviae Miltiorrhizae 550-650 gram, Cortex Moutan 250-350 gram, Mel 130-170 gram, sodium benzoate 2-3 gram, above process for preparing medicine: after Cortex Moutan distilled paeonol, medicinal residues and Radix Salviae Miltiorrhizae decoct with water secondary together, and 2 hours for the first time, 1 hour for the second time, filter, filtrate concentrates, and concentrated solution adds ethanol makes pure content reach 60%, cold preservation (2-2 ℃) 24 hours; Filter, reclaim ethanol to most; Filter, add water-cooled and hid (2-2 ℃) 48 hours; Filter, add the Cortex Moutan distillate, add Mel, sodium benzoate, fill, sterilization.
CN96115634A 1996-02-01 1996-02-01 Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method Expired - Fee Related CN1053374C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN96115634A CN1053374C (en) 1996-02-01 1996-02-01 Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN96115634A CN1053374C (en) 1996-02-01 1996-02-01 Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method

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CN1156047A true CN1156047A (en) 1997-08-06
CN1053374C CN1053374C (en) 2000-06-14

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002032438A1 (en) * 2000-09-13 2002-04-25 Jiangsu Kanion Pharmaceutical Co. Pharmaceutical composition treating gynecological blood stasis diseases, cardio and cerebral vascular diseases, respiratory diseases and the like
CN100370973C (en) * 2005-07-08 2008-02-27 叶耀良 Traditional Chinese medicinal prepn. for treating obstruction of qi in the chest
US8067040B2 (en) 2006-10-18 2011-11-29 Jiangsu Kanion Pharmaceuticals, Co. Ltd. Cinnamomi and poria composition and uses thereof
CN108143783A (en) * 2018-02-26 2018-06-12 潘秀华 A kind of preparation method for the Traditional Chinese medicine lozenge for treating hypertension
CN108175783A (en) * 2018-02-26 2018-06-19 潘秀华 Treat the Traditional Chinese medicine lozenge of hypertension

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100337654C (en) * 2005-08-01 2007-09-19 浙江大学 Composition of Chinese medicine effective ingredients for treating cardiovascular disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1073205A (en) * 1991-12-14 1993-06-16 张洪林 The prescription of compound red-rooted salvia wine and production method

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002032438A1 (en) * 2000-09-13 2002-04-25 Jiangsu Kanion Pharmaceutical Co. Pharmaceutical composition treating gynecological blood stasis diseases, cardio and cerebral vascular diseases, respiratory diseases and the like
US7691387B2 (en) 2000-09-13 2010-04-06 Jiangsu Kanion Pharmaceutical Co., Ltd Cinnamomi and poria composition, method to prepare same and uses thereof
US8119141B2 (en) 2000-09-13 2012-02-21 Jiangsu Kanion Pharmaceutical Co. Ltd. Cinnamomi and poria composition, method to prepare same and uses thereof
CN100370973C (en) * 2005-07-08 2008-02-27 叶耀良 Traditional Chinese medicinal prepn. for treating obstruction of qi in the chest
US8067040B2 (en) 2006-10-18 2011-11-29 Jiangsu Kanion Pharmaceuticals, Co. Ltd. Cinnamomi and poria composition and uses thereof
CN108143783A (en) * 2018-02-26 2018-06-12 潘秀华 A kind of preparation method for the Traditional Chinese medicine lozenge for treating hypertension
CN108175783A (en) * 2018-02-26 2018-06-19 潘秀华 Treat the Traditional Chinese medicine lozenge of hypertension

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