CN1272053C - Chinese medicine for treating tuberculosis and its prepn and use - Google Patents

Chinese medicine for treating tuberculosis and its prepn and use Download PDF

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Publication number
CN1272053C
CN1272053C CNB03157517XA CN03157517A CN1272053C CN 1272053 C CN1272053 C CN 1272053C CN B03157517X A CNB03157517X A CN B03157517XA CN 03157517 A CN03157517 A CN 03157517A CN 1272053 C CN1272053 C CN 1272053C
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chinese medicine
decoction
radix
treating tuberculosis
fried
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CN1526438A (en
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邢文照
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Abstract

The present invention relates to a traditional Chinese medicine for treating tuberculosis, and a preparation method and use thereof. The traditional Chinese medicine for treating tuberculosis aims to solve the problems of big toxin and side effects and unnoticeable therapeutic effect of the existing medicine for treating tuberculosis and is composed of the following raw medicinal materials: ginseng or tangshen, white atractylodes rhizome, common selfheal fruit-spike, isatis root, aster, coltsfoot, common anemarrhena rhizome, centipede, cuttlebone and costazia bone. Consequently, the traditional Chinese medicine for treating tuberculosis has the obvious efficiency of supporting healthy energy to eliminate evil, removing toxin, killing bacteria, reducing fever, relieving cough to relieve asthma and preventing and curing porosis. Moreover, the traditional Chinese medicine for treating tuberculosis has the advantages of safety, no toxic side effect and conspicuous curative effect.

Description

Treat Chinese medicine lungy and its production and use
Technical field
The present invention relates to treatment technology lungy, particularly relate to a kind of treatment Chinese medicine lungy and its production and use.
Background technology
Tuberculosis is that tubercule bacillus is infected by respiratory tract, behind the intrusion lungs, causes that when Abwehrkraft des Koepers reduces the inflammatory infiltration sexually transmitted disease (STD) of lungs becomes.The clinical manifestation weight differs, and former to send out symptom and sign phthisical be light than secondary pulmonary tuberculosis often.In addition, clinical manifestation is relevant with stadium with phthisical type.Common cough, cough up phlegm, part and General Symptoms such as spitting of blood, chest pain, heating, weak, loss of appetite.In time reasonably antituberculosis drugs treat can thoroughly be cured.
China's tradition traditional Chinese medical science claims that pulmonary tuberculosis is a pulmonary tuberculosis, and it is thought: the paathogenic factor of pulmonary tuberculosis has endogenous cause of ill and exopathogenic factor.Exopathogenic factor means infected by tuberculomyces, and the invasion of consumptive disease worm is for suffering from.Endogenous cause of ill means the natural endowment deficiency, loses the day after tomorrow in taking good care of, positive QI-insufficiency, and resistance against diseases is low.The sick position of pulmonary tuberculosis is at lung, and pathogenesis character is mainly the deficiency of YIN, and pathological changes can influence integral body, and biography and spleen, kidney etc. are dirty, so saying of " its heresy tossing about in bed, and takes advantage of into the five internal organs " arranged.
Chemotherapy at present divides two stages: 1, the intensive treatment stage is the tulase that is breeding in a large number, eliminates rapidly, to reduce the root of discharge of bacteria and elimination fastbacteria; 2, the after treatment stage is a control dormancy tulase, and the appearance of metabolic activity tulase to prevent to recur arranged therebetween.
The long-range therapy: strain utilizes streptomycin, isoniazid, paraaminosalicylic acid or streptomycin, isoniazid, ethambutol three medicines to treat, reach the consolidation phase after 2-3 month, continue to use isoniazid and paraaminosalicylic acid or isoniazid and ethambutol to treat 1 year or a year and a half.
Brachytherapy: strain utilizes rifampicin, ethambutol, pyrazinamide, four kinds of Drug therapy 3-3 of isoniazid to reach the consolidation phase after individual month, continues to use rifampicin, ethambutol or Rimactazid to treat drug withdrawal after full 6-9 month.
The patient who finds is wanted early stage begin treatment, drug combination reasonably, dosage will suit, and meets the requirements of the time, patient is cured and seldom recurrence, not so can develop immunity to drugs.
The tuberculosis infectiousness is very strong, and particularly 30-40 age mortality rate in the past is very high.Along with the development of society, medical science leaps at step type, can enough prevent and treats this condition of disease now, and its trend that spreads is under control.But unsatisfactory is: used poisonous side effect of medicine is big, stimulating intestine and stomach is serious, the streptomycin of injection has the significant side effects influence to renal function, life-time service also can cause deafness and tinnitus, and is infertile all the life, indivedual colonies also had can be directed at dead severe allergic reaction.Existing various treatment tuberculosis side effects of pharmaceutical drugs are as follows:
Antituberculotics commonly used
Medicine (abbreviation) Site of action Major side effects
Isoniazid (hydrazine, H, INH) rifampicin (profit, R, RFP) streptomycin (chain, S, SM) pyrazinamide (pyrrole, Z, PIA) ethambutol (second, E, EB, EMB) thiacetazone (urea, T, TB) to ammonia poplar (willow) acid (willow, P, PAS) kanamycin (volume, C, CPM) second (third) isonicotinthioamide (TH second (third) TH1314, TH1312) Inside and outside the inside and outside cell of cell mainly in the extracellular mainly in bacteriostasis bacteriostasis inside and outside the cell of extracellular mainly inside and outside the cell of extracellular Peripheral neuritis, the abnormal liver function anaphylaxis, the abnormal liver function dysaudia, dizzy arthralgia, the abnormal liver function paraesthesia, the visual disorder erythra, abnormal liver function, the granulocytopenia gastrointestinal upset, the anaphylaxis dysaudia, the renal dysfunction gastrointestinal upset, abnormal liver function
As can be seen from the above table: though existing Western medicine curative effect can be satisfactory, comparatively serious toxic and side effects of existence without exception all.Though and existing Chinese medicine is free from side effects, but does not have satisfactory curative effect, so a kind of good effect is badly in need of in reality society, and the new drug that has no side effect again.The inventor had once begun the treatment and the research of Chinese medicine the fifties to this disease, though stayed notes, decreased afterwards.After the reform and opening-up, I continue the research with treatment by Chinese herbs tuberculosis (being the consumptive disease disease) again, through repeatedly improving the following mature technique scheme that obtains finally of summing up.
Summary of the invention
The objective of the invention is to overcome the above-mentioned defective of prior art, provide a kind of and have no side effect, and treatment evident in efficacy Chinese medicine lungy.The present invention also aims to provide the preparation method and the purposes of medicine of the present invention.
For achieving the above object, the present invention treats Chinese medicine lungy and is made by following raw material medicaments:
Radix Ginseng or Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Spica Prunellae, Radix Isatidis, Radix Asteris, Flos Farfarae, the Rhizoma Anemarrhenae, Scolopendra, Os Sepiae, Pumex.
Its principle is: with Radix Ginseng or Radix Codonopsis, Rhizoma Atractylodis Macrocephalae strengthening vital QI to eliminate pathogenic factors, and Spica Prunellae, Radix Isatidis, Scolopendra detoxifcation parasite killing, Radix Asteris, Flos Farfarae, Rhizoma Anemarrhenae clearing and antitussive and Dingchuan, the cavity is controlled in Os Sepiae, the Pumex cough-relieving prevention and cure of schistosomiasis.
As optimization, the weight proportion of its crude drug is:
Radix Ginseng 5-15 or Radix Codonopsis 11-18, Rhizoma Atractylodis Macrocephalae 7-13, Spica Prunellae 18-23, Radix Isatidis 17-24, Radix Asteris 10-20, Flos Farfarae 11-18, Rhizoma Anemarrhenae 12-20, Scolopendra 2-4, Os Sepiae 11-20, Pumex 8-13.
As optimization, the weight proportion of its crude drug more preferably:
Radix Ginseng 10 or Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 10, Spica Prunellae 20, Radix Isatidis 20, Radix Asteris 15, Flos Farfarae 15, the Rhizoma Anemarrhenae 15, Scolopendra 3, Os Sepiae 15, Pumex 10.
It is to make powder behind fried one-tenth decoction of water or the stone roller face that the present invention treats preparation method of Chinese medicine lungy.
As optimization, the fried time after its decoction boils is 15-20 minute.So the restriction to the fried time after boiling is in order better to guarantee the drug effect of decoction.
As optimization, the fried number of times of its decoction is twice, and the gained decoction mixes as the decoction finished product.Adopting fried twice technical scheme is for more pharmacology composition is dissolved in the decoction.Must wring out soup with filtered through gauze in the time of after for the second time fried and remove slag again, otherwise drug effect reduces.
As optimization, its decoction preferred spring water of institute's water of fried time or phreatic water.Preferred spring water of fried water or phreatic water are for making full use of wherein contained mineral.
The application that the present invention treats Chinese medicine lungy is: except that being used to make decoction, the powder, can also be used to make pill, tablet and oral liquid.
The instructions of taking of medicine of the present invention is: decoction, and one pair of medicine fries in shallow oil twice, and the branch that mixes is done three times and is taken, and promptly early services once evening at noon, takes 200 milliliters at every turn.Powder is obeyed 7 grams at every turn, and eliminating cold for resuscitation water send down, also can send down with condiment " hydromel ", in the hope of consolidating curative effect.
The inventor utilizes medicine of the present invention that 20 pulmonary tuberculosis patients are treated, and wherein 19 people fully recover, and 1 people is effective, but does not eradicate, and can not take part in the work, and this patient suffers from emphysema simultaneously.Medicine of the present invention can be used for multiple treatment lungy, can be used for the treatment of pulmonary tuberculosis, tuberculosis of intestine, bone tuberculosis, endobronchial tuberculosis, tuberculosis of cervical lymph nodes, tubercular hemorrhoid complicated by anal fistula, tuberculous peritonitis etc., and cavernous pulmonary tuberculosis is had specially good effect.Quote part typical clinical case below as proof, to prove the practicality of medicine of the present invention:
Example one: Zhuolu County Ma Shui people from village, Hebei province permitted certain lover, 32 years old.This patient is that the big suddenly one evening of autumn in 1962 spitted blood, and is sent to the local medical unit, and the doctor holds a consultation makes film to determine it is cavernous pulmonary tuberculosis, and there are big two holes of egg at the angle on patient's right lung.Medical officers think the disease cannot done anything with somebody to allow it go home supporting, and do not spend money to no avail again.Go home seeing and can not bear and look for me to seek medical advice, have to open a blank sheet of paper side because of the freedom that has the person and not allow her take.End through taking 5 doses of medicine blood of the present invention, it is light to cough, and heat is moved back, health is energetically conscious, connects three doses of clothes again, and she will manage household affairs with descending.Obey 20 doses altogether, check through Army ambulance corps and determine recovery from illness.
Example two: Zhang, the Zhuolu County Mang of Hebei province stone mouth village people, the grade teacher, ill is 1963.He successively arrives district, county, the medical unit, and ground such as Beijing, Tianjin are pulmonary tuberculosis through making a definite diagnosis, and forms the cavity.Bad through treating one section effect, treatment out of funds again have to go home supporting, school's wage freeze, and family financial situation is day by day poor, and it is more difficult to treat, and mental burden increases the weight of, and diet reduces, and health is worn to a shadow.He father-in-law is our distant relative friend, cries to diagnosis and treatment firmly, and I still use the decoction of medicine of the present invention, and through taking 8 doses of medicines, I take a turn for the better at sensation, obey 6 doses again, and subjective symptoms disappears, and diet heightens.This patient is because of family's difficulty drug withdrawal, and then resumes work to it and reissued wage, and mental burden alleviates, and health takes a turn for the better gradually, gets back to work position again, and is healthy now.
This is a few years ago, and it is as follows to treat three tuberculosis patients in the recent period again.
Example three: the Wang, the woman, 15 years old is that I distinguish Xie Jiabao township nine kinds of needles platform people from village.She treats in July, 2002, and my explanation is a tuberculosis, and family members not too believe, have gone to government office sanatorium, and making a definite diagnosis through methods such as film making inspections is pulmonary tuberculosis, returns the here treatment again, the still decoction of medicine of the present invention of usefulness.Take a turn for the better through one section treatment sensation, it is good to look into to this sanatorium again, should several days medicines of reuse, and grind some powder (powder) again and used future so far in January.Learnt afterwards and fully recovered, and returned to school and study.
Example four: the summer, the man, 14 years old, I distinguished holy family hall for worshipping Buddha people from village in my township, also am that government office sanatorium determines it is pulmonary tuberculosis, have also taken Western medicine to take, and am out of use because of responding, and came the still medicine of the present invention of here treatment usefulness, and now return to school after check is fully recovered January.
Example five: Lee, woman, 18 years old, Bei Zhuan people from village of county and town, Laishui, Hebei province plant area, the disease of having graduated from junior middle school on the future trouble.They go to Zhuozhou tuberculosis sanatorium to make a definite diagnosis is pulmonary tuberculosis, and diagnosis and treatment are on March 10th, 2003 outside me, and to go check agree to change through taking ten doses of medicines of the present invention.Return and grab ten doses and also ground the some powder, following so far diagnosis and treatment are now fully recovered, hear in local restaurant and do manual work.
The effect of medicine of the present invention: with Radix Ginseng Rhizoma Atractylodis Macrocephalae strengthening vital QI to eliminate pathogenic factors, Spica Prunellae Radix Isatidis Scolopendra detoxicating, killing bacteria, Radix Asteris Flos Farfarae Rhizoma Anemarrhenae clearing and antitussive and Dingchuan, the cavity is controlled in the Os Sepiae Pumex cough-relieving prevention and cure of schistosomiasis.
Medicine of the present invention is compared with Western medicine and is used for tuberculosis, does not have toxic and side effects especially for pulmonary tuberculosis, compares with existing Chinese medicine to have advantage evident in efficacy.Therefore, have tangible strengthening vital QI to eliminate pathogenic factors, detoxicating, killing bacteria, the effect of clearing and antitussive and Dingchuan and control cavity medicine, and take safe without toxic side effect, advantage evident in efficacy.
The specific embodiment
Below in conjunction with specific embodiment technical scheme of the present invention is further described,
The present invention treats Chinese medicine lungy and is made by following raw materials by weight proportions: (unit of weight gram)
Radix Ginseng 5 .10,15 or Radix Codonopsis 11,15,18, the Rhizoma Atractylodis Macrocephalae 7,10,13, Spica Prunellae 18,20,23, Radix Isatidis 17,20,24, Radix Asteris 10,15,20, Flos Farfarae 11,15,18, the Rhizoma Anemarrhenae 12,15,20, Wu she, 3,4, Os Sepiae 11,15 .20, Pumex 8,10,13.
It is to mix the fried one-tenth decoction of back water by above-mentioned weight proportion that the present invention treats preparation method of Chinese medicine lungy.The fried time after boiling is 15.20 minutes.Fried number of times is twice, and the gained decoction mixes as the decoction finished product, must wring out soup with filtered through gauze in the time of after the second time is fried and remove slag again.Institute's water is a phreatic water when fried, and each amount of water is 1.5 times of crude drug gross weight.Decoction is taken 200 milliliters at every turn.
It is that above-mentioned materials of weight proportions is pulverized that the present invention treats preparation method of Chinese medicine lungy, is mixed and made into powder behind the stone roller face.Each clothes 7 grams of powder.
The application that the present invention treats Chinese medicine lungy is except that being used to make decoction, the powder, can also making pill, tablet and oral liquid.Certainly, tablet also need add other adjuvants such as excipient.

Claims (6)

1, a kind of treatment Chinese medicine lungy is characterized in that being made by following raw materials by weight proportions:
Radix Ginseng 5-15 or Radix Codonopsis 11-18, Rhizoma Atractylodis Macrocephalae 7-13, Spica Prunellae 18-23, Radix Isatidis 17-24, Radix Asteris 10-20, Flos Farfarae 11-18, Rhizoma Anemarrhenae 12-20, Scolopendra 2-4, Os Sepiae 11-20, Pumex 8-13.
2, treatment according to claim 1 Chinese medicine lungy is characterized in that the weight proportion of its crude drug is:
Radix Ginseng 10 or Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 10, Spica Prunellae 20, Radix Isatidis 20, Radix Asteris 15, Flos Farfarae 15, the Rhizoma Anemarrhenae 15, Scolopendra 3, Os Sepiae 15, Pumex 10.
3, the described treatment of claim 1 preparation method of Chinese medicine lungy is characterized in that making powder behind fried one-tenth decoction of water or the stone roller face.
4, method according to claim 3 is characterized in that the fried time after decoction boils is 15-20 minute.
5, method according to claim 3, the fried number of times that it is characterized in that decoction is twice, the gained decoction mixes as the decoction finished product.
6, according to claim 3,4 or 5 described methods, time that it is characterized in that decoction is fried institute's water be spring water or phreatic water.
CNB03157517XA 2003-09-23 2003-09-23 Chinese medicine for treating tuberculosis and its prepn and use Expired - Fee Related CN1272053C (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8858613B2 (en) 2010-09-20 2014-10-14 Altura Medical, Inc. Stent graft delivery systems and associated methods
US9572652B2 (en) 2009-12-01 2017-02-21 Altura Medical, Inc. Modular endograft devices and associated systems and methods

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9572652B2 (en) 2009-12-01 2017-02-21 Altura Medical, Inc. Modular endograft devices and associated systems and methods
US8858613B2 (en) 2010-09-20 2014-10-14 Altura Medical, Inc. Stent graft delivery systems and associated methods

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