CN1636210A - 用于临床试验的病人数据挖掘 - Google Patents

用于临床试验的病人数据挖掘 Download PDF

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CN1636210A
CN1636210A CNA028266579A CN02826657A CN1636210A CN 1636210 A CN1636210 A CN 1636210A CN A028266579 A CNA028266579 A CN A028266579A CN 02826657 A CN02826657 A CN 02826657A CN 1636210 A CN1636210 A CN 1636210A
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R·B·劳
S·米斯拉
L·贝斯特
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Siemens Medical Solutions USA Inc
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Abstract

本发明提供了一种用于为临床试验选择预期的病人的系统和方法。在各种实施例中，临床试验经纪装置被配置为从药品公司接收对满足临床试验规定准则的人员列表的请求。从结构化的计算机化的病人记录(CPR)数据仓库中检索病人记录，所述数据仓库利用从非结构化的医院记录中挖掘的综合病人信息来进行填充。可以输出对其获得了允诺的人员列表并且将该列表转发给对执行临床试验感兴趣并且请求了所述列表的实体。保持病人匿名，直到该病人允诺参与所述临床试验为止。

Description

用于临床试验的病人数据挖掘
相关申请的交叉引用
此申请要求了于2001年11月2日提交的、临时申请序号为60/335,542的美国专利的优先权，将其全部内容引用于此，以供参考。
发明领域
本发明涉及医学信息处理系统，并且更具体来讲涉及一种用于为临床试验选择人员的计算机化系统和方法。
发明背景
选择临床试验的人员是一个高代价的过程。据估计，对于每个所选的参加人员来说它要花费药品公司几千美元。此外，有时、甚至在选择之后，由于不准确的或不正确的信息而必需放弃试验人员。这可能会延迟所述试验，由此导致大得多的花费。
虽然药品公司试图通过发布广告或者通过直接与医师联系来得到外界的理解，但是选择过程通常是相当低效的。医师越来越忙并且不会始终有时间回应病人的请求，而病人未必会阅读临床试验的广告或者订阅在上面发布广告的期刊。
此外，专业化医疗中心的医师势必会引导病人参与该中心主办的试验。由于需要花费以用来了解医师诊治的每个病人的所有可用试验的时间有限，因此许多医师都不知道所有可用的临床试验。
此外，临床试验经常要求非常特殊的选择准则，并且可能难以确定特定的人员是否有符合试验资格。此外，因为医院通常以非结构化的方式存储信息，所以不可能的利用医院记录来选择符合特殊临床试验资格的病人。
同样重要问题在于特定病人与临床试验的匹配。例如，单指癌症来说，在任何时间点都有超过600个的试验在进行。统计表明，临床试验网络站点每星期总计点击75,000次，其主要来自于探求与试验有关信息的病人，所述病人试图加入到试验中。来自于国家癌症研究所(National Cancer Institute)的估计表明，那些适于试验的病人中只有百分之二在进行试验。由此，对于个人来说，知道他或她是否可以适于试验是十分重要的事。
考虑到选择有资格进行临床试验的人员的重要性和费用，提供用于自动地为临床试验选择预期的参加人员的先进技术是合乎需要的并且有益的。
发明概要
本发明提供了一种用于在临床试验中选择预期的参加人员的技术。
在本发明的各种实施例中，提供了一种方法，该方法包括接收对满足临床试验规定准则的预期的参加人员列表的请求。然后检索一组病人记录，以便确定满足所述规定准则的人员。
所述规定准则可以包括概率信息，由此允许病人的选择可以满足用于临床研究的规定准则(例如糖尿病的90％可能性，高血压的70％可能性)。在这种情况下，相关的病人记录往往包括概率信息以允许这种选择。还可以检索每个预期参加人员的附加信息。此附加信息可以包括与参与人员过的其它临床试验有关的信息，包括是否施用过安慰剂(placebo)。
此外，即便需要用来确定人员是否具有临床试验各方面资格的信息不是全都出现，人员也可能被选择。
应该获得参与临床试验的允诺。可以输出获得许可的人员列表，并且将其转发到对执行临床试验感兴趣的实体。通常，所述实体是药品公司。医师可以得知他们的机构审查委员会(Institutional ReviewBoard，IRB)状态(例如‘批准’、‘未决’或者‘未批准’)的通知。可以将他们的状态期满日转发给得到批准的医师。
因为病人的保密性十分重要，所以必须保持满足规定准则的人员匿名。获得允诺的过程可以包括选择与满足规定准则的人员相关联的医师，从每个所选医师中请求批准去参加，并且向满足规定准则的人员提供允诺信息，其中所述人员的医师获得参与所述临床试验的批准。
为了进一步简化所述过程，可以提供调查表。这些调查表可用来确定对应临床试验的资格。
另外，可以为所涉及的当事人确定报酬和费用。例如，参与的医师可以得到报酬。可以向请求列表的实体索要费用。参与临床试验的病人也可以得到报酬。
用于确定临床试验的人员资格的数据源可以包括数据仓库。此外，可以利用从挖掘非结构化的病人记录获得的结构信息来填充所述数据仓库。所述病人记录可以包括从多个参与的卫生保健提供商获得的病人信息，所述卫生保健提供商诸如像医院。
在本发明的各种可替代实施例中，提供了一种用于为个体病人选择预期的临床试验的系统。所述系统包括一个临床试验数据库、一个包含病人信息的数据源以及一个临床试验经纪装置，该经纪装置为满足与临床试验相关联的规定准则的病人生成一个临床试验列表。包含病人信息的所述数据源中的至少一些信息可以从挖掘非结构化的病人记录来获得。
根据以下对优选实施例的详细说明，本发明的这些及其他方面、特征以及优点将变得显而易见，所述优选实施例可结合附图进行阅读。
附图简述
图1是根据本发明实施例、适用于本发明的计算机处理系统的框图；
图2示出了根据本发明实施例的示范性临床试验经纪装置系统；
图3示出了根据本发明另一个实施例的示范性临床试验经纪装置系统；以及
图4示出了概要地描述根据本发明实施例的用于为临床试验选择人员的示范性技术的流程图。
优选实施例的描述
为了易于清楚理解本发明，在此提供了说明的例子，其描述本发明的确定的方面。然而，应该理解的是，这些例证说明不意味着限制本发明的范围，而是在此提供以便举例说明与本发明相关联的确定原理。
还应该理解的是，本发明可以采用硬件、软件、固件、专用处理器或者它们的组合的各种形式来实现。优选的是，本发明以作为确实包括在程序存储装置上的程序的软件来实现。所述程序可以被上载到包括任何适当的体系结构的机器中，并由该机器执行。优选的是，所述机器在具有硬件的计算机平台实现，所述硬件诸如一个或多个中央处理单元(CPU)、随机存取存储器(RAM)以及输入/输出(I/O)接口。计算机平台还包括操作系统以及微指令代码。此处所述的各种过程与功能可以是微指令代码的一部分或者是程序的一部分(或者其组合)，其经由操作系统执行。此外，可以将各种其他外围设备与计算机平台相连接，诸如附加的数据存储设备以及打印设备。
应该理解的是，因为在附图中描述的构成系统部件以及方法步骤是采用软件实现的，所以系统部件(或者过程步骤)之间的实际连接可以不同，取决于编程本发明编程的方式。
图1是根据本发明实施例、适用于本发明的计算机处理系统100的框图。所述系统100包括至少一个处理器(以下称处理器)102，其经由系统总线104可操作地与其他部件耦合。将只读存储器(ROM)106、随机存取存储器(RAM)108、I/O接口110、网络接口112以及外部存储器114可操作地与系统总线104耦合。通过I/O接口110或者网络接口112，可以可操作地把诸如显示装置、盘存储装置(例如磁盘或者光盘存储装置)、键盘以及鼠标的各种外围设备耦合到所述系统总线104。
计算机系统100可以是独立系统或者经由网络接口112与网络相链接。网络接口112可以是硬连线接口。然而，在各种示范性实施例，所述网络接口112可以包括适合于向另一个装置发送并从中接收信息的任何装置，诸如通用异步接收器/发送器(UART)、并行数字接口、软件接口或者已知的或者稍后开发的软件以及硬件的任意组合。所述网络接口可以与各种类型网络相链接，包括局域网(LAN)、广域网(WAN)、内联网、虚拟专用网络(VPN)以及因特网。
所述外部存储器114可以利用数据库管理系统(DBMS)实现，所述数据库管理系统由处理器102管理并且驻留在诸如硬盘的存储器上。然而，应该理解的是，所述外部存储器114可以在一个或多个附加计算机系统上实现。例如，外部存储器114可以包括驻留在独立的计算机系统上的数据仓库系统。
本领域技术人员将理解的是，在不脱离本发明的精神和范围的情况下，可以使用其他可选的计算环境。
参见图2，举例说明了临床试验经纪装置250。示出了所述临床试验经纪装置250可操作地与数据储存库相连，所述数据储存库包含一般从一个或多个卫生保健组织-诸如医院收集的病人信息。将此数据储存库称作结构化的临床病人记录(CPR)280。在本发明的各种实施例中，诸如药品公司210之类的多个药品公司询请求满足临床试验的规定准则的人员列表。然后，查阅所述结构化的CPR 280以获得满足规定准则的人员列表。
所述规定准则可包括概率信息，由此允许病人的选择可以满足用于临床研究的规定准则(例如糖尿病的90％可能性，高血压的70％可能性)。在这种情况下，相关的病人记录往往包括概率信息。
此外，即便需要用来确定病人是否具有临床试验各方面资格的信息不是全都出现，人员也可以被选择。在这种情况下，所述列表往往包括“感兴趣的人员”，其中一些人员可能会因各种原因后来被排除在参与临床试验之外。可以另外提供与每个满足选择的人员有关的信息，包括与该人员参与过的其他临床试验以及是否施用过安慰剂有关的信息。
所述系统可以跟踪多个临床试验，并且维护施用过安慰剂而不是进行药品测试的人员列表。多数情况下，如果他或她参与过类似药品的试验，那么该人将失去试验的资格，然而，如果确定出安慰剂被施用过，那么可以将系统配置为不排除该人员。在其它情况下，所述系统往往提供与人员参与过的试验有关的信息。
如果他们的病人之一满足临床试验的规定准则，那么可以联系诸如医师230之类的医师。在向药品公司发布信息之前，通常必需获得病人医师的同意和要参与所述试验的病人的受通允诺。例如，所述医师230可以向一个病人建议：正由药品公司210进行临床试验的病人往往会受益。可以将试验的细节转发给医师230。此外，医师可以得到他们的机构审查委员会(Institutional Review Board，IRB)状态(例如‘批准’、‘未决’或者‘不批准’)的通知。可以将他们的状态期满日转发给得到批准的医师。
所述临床试验经纪装置250可以得到通知：所提供的病人有意参加。当获得必要的受通允许信息时，临床试验经纪装置250可以向药品公司210提供病人身份(及其他病人信息)。
优选的是，利用数据挖掘技术、以病人信息填充结构化的CPR280，所述数据挖掘技术在由Rao及其他人与本申请一起提交的序号为10/_，_，(代理人编号2001 P20906US01)、标题为“Patient DataMining(病人数据挖掘)”的共同待审的美国专利申请中有所描述，将该篇申请的内容引用于此，以供参考。
该公开内容讲授了用于挖掘高质量结构化的临床信息的数据挖掘框架。所述数据挖掘框架包括数据挖掘器，用于根据知识库中包含的领域专用知识、从计算机化的病人记录中挖掘医学信息。所述数据挖掘器包括用于从计算机化的病人记录中提取信息的部件，随时间以有原则的方式组合所有可用证据的部件，以及从此组合过程得出推理的部件。将挖掘的医学信息存储在结构化的、计算机化的病人记录中。
为了确定临床研究的规定准则，通常需要参考多个数据源。例如，为了确定病人是否是糖尿病患者，所述系统可能要审查以下信息：
(a)与糖尿病相关联的二次诊断的ICD-9计帐代码；
(b)给病人施用的、与糖尿病治疗有关的药物(胰岛素)；
(c)是糖尿病的症候的病人的实验值(例如，两个连续的血糖读数超过250mg/d)；
(d)医生提及该病人在H&P(历史&实际)或出院注释(自由文本)中是糖尿病；以及
(e)与糖尿病相关联的病人过程(例如，脚的检查)。
可以看出，有多个独立的信息来源，从中的现察结果可以支持(用不同的可信度)病人是糖尿病患者(或者一般地说有某个疾病/状况)。它们并不是全部都存在，事实上在某些情况下它们还相互矛盾。可以导出概率观察结果，具有可变的可信度。从概率上可以把这些观察结果(例如，有关计帐代码、药物、实验室测试等等)组合在一起以得出最终的糖尿病概率。注意病人记录中可能有与糖尿病矛盾的信息。例如，病人具有某种有压力的事件发生(例如，一次操作)并且血糖上不去。
应该理解的是，临床试验的病人选择可以基于概率信息。由此，满足规定准则的病人列表可以包括可能(例如根据特定的可信度)已经满足临床试验标准的病人列表。
由于获得附加信息或者验证与参加人员有关的信息可能是必需的，所以临床试验经纪装置250可以输出或者另外提供调查表。这些调查表可被用来确定对应临床试验的资格。例如，可以要求所述病人提供特定疾病的详细家族史。
除了提供满足所述规定准则的人员列表之外，临床试验经纪装置250还可以计算各种支付和费用。例如，参加的医师可能需要得到报酬。可以向所述药品公司为所述列表索要费用。另外，参加临床试验的人员也可以得到报酬。
在本发明的各种实施例中，可以生成具有确定类型的临床试验预合格的人员列表。这些预合格个体列表可以为药品公司所获得，或者为对进行临床试验感兴趣的其他实体获得。
参见图3，举例说明了本发明的可替代的实施例。在这些实施例中，临床试验经纪装置350能够访问包含挖掘的结构化的病人信息的、结构化的CPR 380，并且还可以访问包含与各种临床试验有关的信息的临床试验数据库390。临床试验数据库390中的信息可以包括涉及临床试验资格的信息，以及涉及这些试验的其他信息。诸如病人335之类的病人可以请求与特定临床试验有关的信息。所述病人可以直接地访问临床试验经纪装置350或者通过诸如医师330之类的医师访问。所述临床试验经纪装置330可以访问结构化的CPR 380(利用与CPR280相同的方式用信息来进行填充)，以便检索有关病人的信息，并且试图根据病人的病历来匹配病人感兴趣的临床试验和可以利用的试验。
参见图4，举例说明了概要地描述用于为临床试验选择人员的示范性技术的流程图。从步骤401开始，从满足规定准则的一组人员中选择人员。这一步骤可以包括接收对满足临床试验规定准则的人员列表的请求，并且从数据源中检索一组病人记录以便确定满足规定准则的人员。
例如，药品公司可能对选择是糖尿病患者以及最近三年内有心脏病发作的黑人男子感兴趣。这可用来测试新药。
利用传统方法，满足上述选择标准是十分困难的，这是因为计算机化的医院数据库通常不存储这种信息。然而，通过采用数据挖掘技术，可以利用这种病人信息来填充结构化的CPR，由此允许此选择标准被满足，所述数据挖掘技术在由Rao及其他人与本申请一起提交的序号为10/__，_，(代理人编号为2001P20906US01)、标题为“PatientData Mining(病人数据挖掘)”的共同待审的美国专利申请中作了描述。
在步骤402中，可以通知一个人员的医师：为该临床试验选择了这个人。就此，还可以通知医院的机构审查委员会(IRB)。如果IRB批准早已被授权在该站点试验，或者如果医师需要等待IRB批准此试验，那么还可以通知该医师。接下来，在步骤403中，作出关于该医师是否将参与研究的判定。如果确定该医师将参与，那么控制继续到步骤404；否则在步骤408终止控制。
在步骤404中，通知所述人员：他或她可能有资格参加临床试验。可以直接地联系所述病人，或者通过医师间接地联系所述病人。就此，可以给与该病人关于临床试验的详细信息。诸如可以通过调查表来为附加信息而询问病人。所述调查表可用来确定用于研究的资格和/或作为获得附加有用信息的方式。
接下来，在步骤405中，判断该人员是否表明希望参与临床试验。如果该人员通知他或者她的医师有意去参加，那么控制继续到步骤406；否则在步骤408终止控制。
在步骤406中，获得发布的信息。就此，可以给所述人员提供一个允诺表格，或者把由他或她的医师提供给他的完整的一个表格寄给他。还可以提供涉及参加人员报酬的任何信息，包括偿还款项。控制继续到步骤407。
在步骤407中，可以确定费用和酬金。举例来说，可以向请求病人列表的实体因病人列表而索要适当的酬金。此外，所述医师和试验参加人员还可以因他们参与研究而获得报酬。控制继续到步骤408，其中所述操作停止。
如图1-4所示，优选的是，本发明利用通用计算机系统实现。然而，本发明的系统和方法可以利用一个或多个编程的通用计算机、编程的微处理器或者微控制器以及外围集成电路元件、ASIC或者其他集成电路、数字信号处理器、诸如分立元件电路的硬连接的电子或逻辑电路、诸如PLD、PLA、FPGA或者PAL等等的可编程逻辑器件的任何组合来实现。总的来说，能够实现有限状态机的任何装置都可用来实现此系统，所述有限状态机又能够实现图4中所示流程。
虽然已经参照附图在此描述了本发明的例证性实施例，但是应该理解的是，本发明不局限于那些具体的实施例，在不脱离本发明的范围或精神的情况下，本领域技术人员可以对其做出各种其他的改变和修改。

Claims (37)

1.一种用于在临床试验中选择预期的参加人员的系统，包括：
一个包含病人信息的数据源，所述病人信息中的至少一些病人信息从挖掘非结构化的病人记录而获得；以及
一个临床试验经纪装置，用于从所述数据源检索一组病人记录，并且生成满足与所述临床试验相关联的规定准则的人员列表。
2.如权利要求1所述的系统，其中所述临床试验经纪装置被配置为从一个或多个满足规定准则的人员中获得允诺。
3.如权利要求1所述的系统，其中对执行所述临床试验感兴趣的实体请求所述满足规定准则的人员列表。
4.如权利要求1所述的系统，其中保持满足规定准则的人员匿名，直到提供了允诺为止。
5.如权利要求1所述的系统，其中满足规定准则的人员列表包括临床试验的预合格人员。
6.如权利要求1所述的系统，其中所述数据源包括从多个医院收集的信息。
7.如权利要求1所述的系统，其中所述规定准则包括概率准则。
8.如权利要求1所述的系统，其中所获得的病人记录包括概率信息。
9.如权利要求1所述的系统，其中需要确定病人在各个方面是否合格的信息不包括在所获得的病人记录中。
10.如权利要求1所述的系统，其中提供了与列表中每个人有关的信息。
11.如权利要求10所述的系统，其中所述信息包括涉及所述人员参与过的先前临床试验的信息。
12.一种用于在临床试验中选择预期的参加人员的方法，包括以下步骤：
接收对满足与临床试验相关联的规定准则的人员列表的请求；并且
从数据源检索一组病人记录以便确定满足所述规定准则的人员。
13.如权利要求12所述的方法，进一步包括步骤：
从一个或多个满足所述规定准则的人员中获得参与该临床试验的允诺；以及
输出从其获得了允诺的人员列表。
14.如权利要求13所述的方法，还包括向对执行所述临床试验感兴趣的实体转发人员列表的步骤。
15.如权利要求13所述的方法，其中获得允诺的步骤包括以下步骤：
选择与满足所述规定准则的人员相关联的的医师；
从每个所选择的医师中请求批准参加；以及
如果批准人员的医师提供了参与所述临床试验的批准，那么向满足所述规定准则的人员提供允诺信息。
16.如权利要求13所述的方法，其中获得允诺包括向医师通知他们的机构审查委员会状态。
17.如权利要求16所述的方法，其中获得允诺进一步包括向已接收状态的医师转发他们的机构审查委员会批准的期满日。
18.如权利要求14所述的方法，其中从对执行所述临床试验感兴趣的实体接收人员列表的请求。
19.如权利要求12所述的方法，其中满足所述规定准则的人员的匿名被保持，直到提供了允诺为止。
20.如权利要求12所述的方法，进一步包括提供调查表的步骤。
21.如权利要求20所述的方法，其中所述调查表用于确定符合临床试验的资格。
22.如权利要求14所述的方法，其中向请求病人列表的实体因病人列表索要费用。
23.如权利要求14所述的方法，其中向参与临床试验的人员会给予报酬。
24.如权利要求15所述的方法，其中向参加的医师给予补偿。
25.如权利要求12所述的方法，其中所述数据源是数据仓库。
26.如权利要求25所述的方法，其中所述数据仓库利用从挖掘非结构化的病人记录而获得的信息来填充。
27.如权利要求12所述的方法，其中从药品公司接收所述请求。
28.如权利要求12所述的方法，其中所述数据源包括从多个医院收集的信息。
29.如权利要求12所述的方法，其中所述规定准则包括概率值。
30.如权利要求29所述的方法，其中所述概率值包括可信区间。
31.如权利要求12所述的方法，其中所获得的病人记录包括概率信息。
32.如权利要求12所述的方法，其中需要用来确定病人是否在各个方面都合格的信息不包括在所获得的病人记录中。
33.如权利要求12所述的方法，其中生成与列表中每个人员有关的信息。
34.如权利要求12所述的方法，其中所述信息包括涉及所述人员参与过的先前临床试验的信息。
33.一种机器可读的程序存储设备，确实地包括一个指令程序，该指令程序可在机器上执行，以实施用于在临床试验中选择预期的参与人员的方法步骤，所述方法步骤包括：
接收对满足与临床试验相关联的规定准则的人员列表的请求；并且
从数据源中检索一组病人记录，以便确定满足所述规定准则的人员。
34.一种用于为个体病人选择预期的临床试验的系统，包括：
临床试验数据库；
包含病人信息的数据源；和
临床试验经纪装置，用于生成满足与临床试验相关联的规定准则的病人的临床试验列表。
35.如权利要求34所述的系统，其中包含病人信息的数据源中的至少一些信息从挖掘非结构化的病人记录而获得。
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104919450A (zh) * 2012-12-10 2015-09-16 皇家飞利浦有限公司 用于令多站点性能测量匿名并且用于控制对匿名数据的动作以及重新识别的方法和系统
CN108986917A (zh) * 2018-06-14 2018-12-11 杭州认知网络科技有限公司 临床试验匹配方法、装置及终端设备
CN111433862A (zh) * 2017-11-02 2020-07-17 皇家飞利浦有限公司 临床决策支持
CN113674867A (zh) * 2021-07-27 2021-11-19 上海药慧信息技术有限公司 临床数据挖掘方法、装置、电子设备和存储介质

Families Citing this family (433)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660176A (en) 1993-12-29 1997-08-26 First Opinion Corporation Computerized medical diagnostic and treatment advice system
USRE43433E1 (en) 1993-12-29 2012-05-29 Clinical Decision Support, Llc Computerized medical diagnostic and treatment advice system
US6206829B1 (en) 1996-07-12 2001-03-27 First Opinion Corporation Computerized medical diagnostic and treatment advice system including network access
US5935060A (en) 1996-07-12 1999-08-10 First Opinion Corporation Computerized medical diagnostic and treatment advice system including list based processing
CN1252877A (zh) 1997-03-13 2000-05-10 第一咨询公司 疾病处理系统
US20020068857A1 (en) 2000-02-14 2002-06-06 Iliff Edwin C. Automated diagnostic system and method including reuse of diagnostic objects
US7415447B2 (en) * 2001-04-02 2008-08-19 Invivodata, Inc. Apparatus and method for prediction and management of participant compliance in clinical research
DE10140329A1 (de) * 2001-08-16 2003-03-06 Siemens Ag Verfahren und System zur Überprüfung von Kodierungen im Gesundheitswesen
JP2005523490A (ja) * 2001-11-02 2005-08-04 シーメンス　メディカル　ソリューションズ　ユーエスエー　インコーポレイテッド コンプライアンス自動化のための患者データマイニング
US8949082B2 (en) 2001-11-02 2015-02-03 Siemens Medical Solutions Usa, Inc. Healthcare information technology system for predicting or preventing readmissions
US7558611B2 (en) * 2001-11-24 2009-07-07 Image Analysis, Inc. Automatic detection and quantification of coronary and aortic calcium
US8649843B2 (en) * 2001-11-24 2014-02-11 Ben A. Arnold Automated calcium scoring of the aorta
US7457731B2 (en) * 2001-12-14 2008-11-25 Siemens Medical Solutions Usa, Inc. Early detection of disease outbreak using electronic patient data to reduce public health threat from bio-terrorism
US8620677B2 (en) 2002-04-09 2013-12-31 Pcrs, Inc. Online, interactive evaluation of research performance
US20060259329A1 (en) * 2002-04-09 2006-11-16 Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Medical Center System and Method for Determining the Degree of Abnormality of a Patient's Vital Signs
US8560582B2 (en) 2002-08-12 2013-10-15 Jeffrey Saul Harris Method for analyzing records in a data base
US20050288571A1 (en) 2002-08-20 2005-12-29 Welch Allyn, Inc. Mobile medical workstation
US20040186357A1 (en) * 2002-08-20 2004-09-23 Welch Allyn, Inc. Diagnostic instrument workstation
US7680086B2 (en) 2002-09-09 2010-03-16 Siemens Canada Limited Wireless local area network with clients having extended freedom of movement
WO2004032017A1 (en) * 2002-10-01 2004-04-15 Yonsei University Liver cancer forecasting system for early diagnosis and control method thereof
US6826578B2 (en) * 2002-10-25 2004-11-30 Ge Medical Systems Information Technolgoies, Inc. Method, system, and computer product for collecting and distributing clinical data for data mining
US7244230B2 (en) * 2002-11-08 2007-07-17 Siemens Medical Solutions Usa, Inc. Computer aided diagnostic assistance for medical imaging
US20070106531A1 (en) * 2002-11-08 2007-05-10 Daniel Deakter Method and process that automatically finds patients for clinical drug or device trials
US7401028B2 (en) * 2002-11-08 2008-07-15 Deakter Daniel R System and process for matching patients with clinical medical trials
US20040167908A1 (en) * 2002-12-06 2004-08-26 Attensity Corporation Integration of structured data with free text for data mining
US11335446B2 (en) * 2002-12-06 2022-05-17 Quality Healthcare Intermediary, Llc Method of optimizing healthcare services consumption
US20040172293A1 (en) * 2003-01-21 2004-09-02 Paul Bruschi Method for identifying and communicating with potential clinical trial participants
WO2004089184A2 (en) * 2003-04-01 2004-10-21 Diadexus, Inc. NEW USES OF Lp-PLA2 IN COMBINATION TO ASSESS CORONARY RISK
US20040215656A1 (en) * 2003-04-25 2004-10-28 Marcus Dill Automated data mining runs
US7780595B2 (en) 2003-05-15 2010-08-24 Clinical Decision Support, Llc Panel diagnostic method and system
US9060770B2 (en) 2003-05-20 2015-06-23 Ethicon Endo-Surgery, Inc. Robotically-driven surgical instrument with E-beam driver
US7912528B2 (en) * 2003-06-25 2011-03-22 Siemens Medical Solutions Usa, Inc. Systems and methods for automated diagnosis and decision support for heart related diseases and conditions
EP1636731A2 (en) * 2003-06-25 2006-03-22 Siemens Medical Solutions USA, Inc. Systems and methods for automated diagnosis and decision support for breast imaging
CN1567303A (zh) * 2003-07-03 2005-01-19 富士通株式会社 结构文档信息块的自动分割方法和装置
US20050021489A1 (en) * 2003-07-22 2005-01-27 Microsoft Corporation Data mining structure
CA2535133C (en) * 2003-08-13 2011-03-08 Siemens Medical Solutions Usa, Inc. Computer-aided decision support systems and methods
US8412541B2 (en) 2003-08-14 2013-04-02 Edda Technology, Inc. Method and system for intelligent qualitative and quantitative analysis for medical diagnosis
US20070255584A1 (en) * 2003-09-08 2007-11-01 Pavlatos Christ J Patient Physician Connectivity System and Method
WO2005029252A2 (en) 2003-09-15 2005-03-31 Idx Systems Corporation Executing clinical practice guidelines
US20050071462A1 (en) * 2003-09-30 2005-03-31 Ibm Corporation Creating user metric patterns
AU2004280966A1 (en) * 2003-10-07 2005-04-21 Entelos, Inc. Simulating patient-specific outcomes
US7865373B2 (en) * 2003-10-15 2011-01-04 Medical Web Technologies, Inc. Method and apparatus for sharing healthcare data
US20070073555A1 (en) * 2003-10-29 2007-03-29 Patientrack Pty Ltd. System and process for facilitating the provision of health care
US20060020215A1 (en) * 2003-11-06 2006-01-26 Callahan Alfred S Iii Systems and methods for health screening for vascular disease
US7152785B2 (en) * 2003-12-09 2006-12-26 Ge Medical Systems Global Technology Company, Llc Patient-centric data acquisition protocol selection and identification tags therefor
US7376644B2 (en) * 2004-02-02 2008-05-20 Ram Consulting Inc. Knowledge portal for accessing, analyzing and standardizing data
US7653227B2 (en) * 2004-02-09 2010-01-26 Siemens Medical Solutions Usa, Inc. Hierarchical modeling in medical abnormality detection
US20070142979A1 (en) * 2004-02-18 2007-06-21 Klaus Abraham-Fuchs Method for the selection of a participant in a medical project with selection criteria for patients
US20050182665A1 (en) * 2004-02-18 2005-08-18 Klaus Abraham-Fuchs Method of recruiting patients for a clinical study
US20070150305A1 (en) * 2004-02-18 2007-06-28 Klaus Abraham-Fuchs Method for selecting a potential participant for a medical study on the basis of a selection criterion
US20050192843A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for validating patient and medical devices information
US20050192836A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for delivering and gathering medical diagnostic data
US20050192842A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for authorizing and processing reimbursements for services provided in the collection of implantable medical device data
US20050192844A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for automatically collecting, formatting, and storing medical device data in a database
US20050192838A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for accessing and distributing medical information
US20050192649A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for providing variable medical information
US7976539B2 (en) 2004-03-05 2011-07-12 Hansen Medical, Inc. System and method for denaturing and fixing collagenous tissue
US20060100610A1 (en) 2004-03-05 2006-05-11 Wallace Daniel T Methods using a robotic catheter system
US20050203776A1 (en) * 2004-03-15 2005-09-15 Godwin Sharen A. Method of identifying clinical trial participants
US8155977B2 (en) * 2004-04-15 2012-04-10 The Trizetto Group, Inc. Rule management method and system
US7306562B1 (en) 2004-04-23 2007-12-11 Medical Software, Llc Medical risk assessment method and program product
US7949545B1 (en) 2004-05-03 2011-05-24 The Medical RecordBank, Inc. Method and apparatus for providing a centralized medical record system
EP1779281A1 (en) * 2004-08-10 2007-05-02 Koninklijke Philips Electronics N.V. System and method for configuring clinical care setting for a patient according to clinical guidelines
SG120301A1 (en) * 2004-08-27 2006-03-28 Univ Nanyang Home ultrasound system
NL1027047C2 (nl) * 2004-09-15 2006-03-16 Roderik Adriaan Kraaijenhagen Computerinrichting voor het vaststellen van een diagnose.
US20060064017A1 (en) * 2004-09-21 2006-03-23 Sriram Krishnan Hierarchical medical image view determination
US20060074315A1 (en) * 2004-10-04 2006-04-06 Jianming Liang Medical diagnostic ultrasound characterization of cardiac motion
US20060074312A1 (en) * 2004-10-06 2006-04-06 Bogdan Georgescu Medical diagnostic ultrasound signal extraction
US20060101072A1 (en) * 2004-10-21 2006-05-11 International Business Machines Corproation System and method for interpreting scan data
US9081879B2 (en) 2004-10-22 2015-07-14 Clinical Decision Support, Llc Matrix interface for medical diagnostic and treatment advice system and method
US20060101075A1 (en) * 2004-11-10 2006-05-11 Peter Lehel Method and system for prospectively acquiring ROI based data for retrospective re-analysis
US20060136259A1 (en) * 2004-12-17 2006-06-22 General Electric Company Multi-dimensional analysis of medical data
JP4797380B2 (ja) * 2004-12-28 2011-10-19 コニカミノルタホールディングス株式会社 医療支援システム
US20060247544A1 (en) * 2005-02-03 2006-11-02 Maleeha Qazi Characterization of cardiac motion with spatial relationship
US7870416B2 (en) * 2005-02-07 2011-01-11 Mimosa Systems, Inc. Enterprise service availability through identity preservation
US8271436B2 (en) * 2005-02-07 2012-09-18 Mimosa Systems, Inc. Retro-fitting synthetic full copies of data
US8543542B2 (en) * 2005-02-07 2013-09-24 Mimosa Systems, Inc. Synthetic full copies of data and dynamic bulk-to-brick transformation
US7778976B2 (en) 2005-02-07 2010-08-17 Mimosa, Inc. Multi-dimensional surrogates for data management
US8799206B2 (en) * 2005-02-07 2014-08-05 Mimosa Systems, Inc. Dynamic bulk-to-brick transformation of data
US8812433B2 (en) 2005-02-07 2014-08-19 Mimosa Systems, Inc. Dynamic bulk-to-brick transformation of data
US8161318B2 (en) * 2005-02-07 2012-04-17 Mimosa Systems, Inc. Enterprise service availability through identity preservation
US7917475B2 (en) * 2005-02-07 2011-03-29 Mimosa Systems, Inc. Enterprise server version migration through identity preservation
US7657780B2 (en) 2005-02-07 2010-02-02 Mimosa Systems, Inc. Enterprise service availability through identity preservation
US8918366B2 (en) 2005-02-07 2014-12-23 Mimosa Systems, Inc. Synthetic full copies of data and dynamic bulk-to-brick transformation
US7650321B2 (en) * 2005-02-16 2010-01-19 Siemens Medical Solutions Usa, Inc. Two classifier based system for classifying anomalous medical patient records
DE102005008386A1 (de) * 2005-02-23 2006-08-24 Siemens Ag Verfahren und Vorrichtung zur präventiven Gesundheitsüberwachung von Patienten
US20060210133A1 (en) 2005-03-03 2006-09-21 Sriram Krishnan Performance adjustments in medical decision support systems
US7657521B2 (en) * 2005-04-15 2010-02-02 General Electric Company System and method for parsing medical data
US20060265253A1 (en) * 2005-05-18 2006-11-23 Rao R B Patient data mining improvements
US20090049104A1 (en) * 2005-06-08 2009-02-19 William Pan Method and system for configuring a variety of medical information
US7849048B2 (en) 2005-07-05 2010-12-07 Clarabridge, Inc. System and method of making unstructured data available to structured data analysis tools
US7849049B2 (en) 2005-07-05 2010-12-07 Clarabridge, Inc. Schema and ETL tools for structured and unstructured data
JP4619219B2 (ja) * 2005-07-19 2011-01-26 株式会社エヌ・ティ・ティ・データ 被験者選定装置
US7685000B1 (en) * 2005-08-10 2010-03-23 Matria Healthcare, Inc. Predictive modeling system and method for disease management
CN101501667A (zh) * 2005-08-23 2009-08-05 米谋萨系统有限公司 通过身份保持的企业服务器版本迁移
US7630947B2 (en) * 2005-08-25 2009-12-08 Siemens Medical Solutions Usa, Inc. Medical ontologies for computer assisted clinical decision support
US20070156720A1 (en) * 2005-08-31 2007-07-05 Eagleforce Associates System for hypothesis generation
US20070067189A1 (en) * 2005-09-16 2007-03-22 Numoda Corporation Method and apparatus for screening, enrollment and management of patients in clinical trials
US7624098B2 (en) * 2005-10-07 2009-11-24 International Business Machines Corporation Generating suitable data for statistical analysis
EP1946235B1 (en) * 2005-10-31 2018-09-12 Koninklijke Philips N.V. System and method for clinical workflow management
WO2007058997A2 (en) * 2005-11-11 2007-05-24 The University Of Houston System Scoring method for imaging-based detection of vulnerable patients
US20070118399A1 (en) * 2005-11-22 2007-05-24 Avinash Gopal B System and method for integrated learning and understanding of healthcare informatics
US20070120640A1 (en) * 2005-11-28 2007-05-31 Han-Ming Lee Plug with overload protection and a safety switch
CA2632730C (en) * 2005-12-06 2018-12-18 Ingenix, Inc. Analyzing administrative healthcare claims data and other data sources
US20070133851A1 (en) * 2005-12-12 2007-06-14 General Electric Company Method and apparatus for selecting computer-assisted algorithms based on protocol and/or parameters of an acquisistion system
EP1808790A1 (en) * 2005-12-15 2007-07-18 Statlife Method of determining risk scores
US20070150372A1 (en) * 2005-12-19 2007-06-28 Roy Schoenberg Vendor and Consumer Matching
US20070168345A1 (en) * 2006-01-17 2007-07-19 Andrew Gibbs System and method of identifying subject matter experts
US8670997B2 (en) 2006-02-09 2014-03-11 Siemens Medical Solutions Usa, Inc. Quality metric extraction and editing for medical data
US20090054740A1 (en) * 2006-03-03 2009-02-26 Mentis Cura Ehf Method and apparatus of constructing and using a reference tool to generate a discriminatory signal for indicating a medical condition of a subject
US7593927B2 (en) * 2006-03-10 2009-09-22 Microsoft Corporation Unstructured data in a mining model language
US20100081941A1 (en) * 2006-03-22 2010-04-01 Endothelix, Inc. Cardiovascular health station methods and apparatus
US8920343B2 (en) 2006-03-23 2014-12-30 Michael Edward Sabatino Apparatus for acquiring and processing of physiological auditory signals
US10410308B2 (en) * 2006-04-14 2019-09-10 Fuzzmed, Inc. System, method, and device for personal medical care, intelligent analysis, and diagnosis
US7805385B2 (en) * 2006-04-17 2010-09-28 Siemens Medical Solutions Usa, Inc. Prognosis modeling from literature and other sources
US7844560B2 (en) * 2006-04-17 2010-11-30 Siemens Medical Solutions Usa, Inc. Personalized prognosis modeling in medical treatment planning
US20070250347A1 (en) * 2006-04-25 2007-10-25 Klaus Abraham-Fuchs Broker service and system architecture for health care data
US20070255704A1 (en) * 2006-04-26 2007-11-01 Baek Ock K Method and system of de-identification of a record
FR2901042B1 (fr) * 2006-05-15 2008-08-22 Clinigrid Sarl Systeme et procede de gestion de donnees relatives a un patient dans le cadre d'une operation d'evaluation
US20080195600A1 (en) * 2006-05-25 2008-08-14 Deakter Daniel R Efficient method and process to search structured and unstructured patient data to match patients to clinical drug/device trials
JP4960024B2 (ja) * 2006-06-07 2012-06-27 オリンパスメディカルシステムズ株式会社 医療画像管理方法ならびにそれを利用した医療画像管理装置
US20070294113A1 (en) * 2006-06-14 2007-12-20 General Electric Company Method for evaluating correlations between structured and normalized information on genetic variations between humans and their personal clinical patient data from electronic medical patient records
US20070294112A1 (en) * 2006-06-14 2007-12-20 General Electric Company Systems and methods for identification and/or evaluation of potential safety concerns associated with a medical therapy
US20080015893A1 (en) * 2006-07-17 2008-01-17 Walgreen Co. Identification of Inappropriate Medications In A Medication Therapy Regimen
US20080126130A1 (en) * 2006-07-17 2008-05-29 Walgreen Co. Compliance With A Medication Therapy Regimen
US8478605B2 (en) * 2006-07-17 2013-07-02 Walgreen Co. Appropriateness of a medication therapy regimen
US8700430B2 (en) * 2006-07-17 2014-04-15 Walgreen Co. Optimization of a medication therapy regimen
US20100235378A1 (en) * 2006-08-22 2010-09-16 Lead Horse Technologies, Inc. Medical assessment support system and method
US7840511B2 (en) * 2006-09-06 2010-11-23 Siemens Medical Solutions Usa, Inc. Learning or inferring medical concepts from medical transcripts using probabilistic models with words or phrases identification
JP4997892B2 (ja) * 2006-09-19 2012-08-08 富士ゼロックス株式会社 検索システム、検索方法及び検索プログラム
US7558416B2 (en) 2006-10-02 2009-07-07 Johnson & Johnson Consumer Companies, Inc. Apparatus and method for measuring photodamage to skin
US20080126167A1 (en) * 2006-10-24 2008-05-29 Mid-America Consulting Group Invitee-participant matching system for meeting scheduling
PL2097794T5 (pl) * 2006-11-03 2018-01-31 Air Prod & Chem System i sposób monitorowania procesu
US8688475B2 (en) * 2006-11-10 2014-04-01 General Electric Company Method and system for clinical trial compliance
US20080140371A1 (en) * 2006-11-15 2008-06-12 General Electric Company System and method for treating a patient
US20080133275A1 (en) * 2006-11-28 2008-06-05 Ihc Intellectual Asset Management, Llc Systems and methods for exploiting missing clinical data
US8200506B2 (en) * 2006-12-19 2012-06-12 Accenture Global Services Limited Integrated health management platform
US20080154642A1 (en) * 2006-12-21 2008-06-26 Susan Marble Healthcare Core Measure Tracking Software and Database
US8140352B2 (en) * 2007-01-03 2012-03-20 Performance Clinical Systems, Llc Order sets having different views for CPOE systems
US8566727B2 (en) * 2007-01-03 2013-10-22 General Electric Company Method and system for automating a user interface
US7899764B2 (en) * 2007-02-16 2011-03-01 Siemens Aktiengesellschaft Medical ontologies for machine learning and decision support
US20080201429A1 (en) * 2007-02-16 2008-08-21 Siemens Medical Solutions Usa, Inc. System Supporting Live Electronic Messaging Communication Between A Healthcare Worker And A Patient
US20080208624A1 (en) * 2007-02-22 2008-08-28 General Electric Company Methods and systems for providing clinical display and search of electronic medical record data from a variety of information systems
JP4640845B2 (ja) * 2007-03-05 2011-03-02 富士フイルム株式会社 画像処理装置およびそのプログラム
US20080221929A1 (en) * 2007-03-09 2008-09-11 Cerner Innovation, Inc. System and method for associating a patient specimen identifier with a radiology image for the patient
US8031920B2 (en) * 2007-03-09 2011-10-04 Cerner Innovation, Inc. System and method for associating electronic images in the healthcare environment
US7936908B2 (en) * 2007-03-09 2011-05-03 Cerner Innovation, Inc. Graphical user interface for displaying a radiology image for a patient and an associated laboratory report summary
US20080228522A1 (en) * 2007-03-12 2008-09-18 General Electric Company Enterprise medical imaging and information management system with clinical data mining capabilities and method of use
US20080228769A1 (en) * 2007-03-15 2008-09-18 Siemens Medical Solutions Usa, Inc. Medical Entity Extraction From Patient Data
US20110124975A1 (en) * 2007-03-16 2011-05-26 Arthur Solomon Thompson Method for Medical Diagnosis Utilizing PDA Software Robots
CN105335606B (zh) * 2007-04-13 2021-05-25 皇家飞利浦电子股份有限公司 用于确定临床事件之间的相关性的方法和系统
US7873414B2 (en) * 2007-04-17 2011-01-18 Cardiac Pacemakers, Inc. Patient characteristic based adaptive anti-tachy pacing programming
US20080270180A1 (en) * 2007-04-30 2008-10-30 Intuit Inc. Method and system for health care data transfer
US8571883B2 (en) * 2007-05-10 2013-10-29 Eveready Battery Company, Inc. Image analysis processes and methods for the evaluation of tampon performance
US20090055217A1 (en) * 2007-08-23 2009-02-26 Grichnik Anthony J Method and system for identifying and communicating a health risk
US8260636B2 (en) * 2007-08-31 2012-09-04 Caterpillar Inc. Method and system for prioritizing communication of a health risk
US20090070137A1 (en) * 2007-09-10 2009-03-12 Sultan Haider Method and system to optimize quality of patient care paths
US20090070146A1 (en) * 2007-09-10 2009-03-12 Sultan Haider Method for managing the release of data
US20090187425A1 (en) * 2007-09-17 2009-07-23 Arthur Solomon Thompson PDA software robots leveraging past history in seconds with software robots
US7895061B2 (en) * 2007-10-02 2011-02-22 American Well Corporation Auctioning provider prices
JP5159242B2 (ja) * 2007-10-18 2013-03-06 キヤノン株式会社 診断支援装置、診断支援装置の制御方法、およびそのプログラム
US20090254371A1 (en) * 2007-12-05 2009-10-08 Bartholomew Iii Samuel W Quality Assurance Methods for Medication Therapy Management
CN101903887B (zh) * 2007-12-21 2014-06-11 皇家飞利浦电子股份有限公司 对临床决策支持系统的连续版本的半自动验证
US9997260B2 (en) * 2007-12-28 2018-06-12 Koninklijke Philips N.V. Retrieval of similar patient cases based on disease probability vectors
US8812240B2 (en) * 2008-03-13 2014-08-19 Siemens Medical Solutions Usa, Inc. Dose distribution modeling by region from functional imaging
US8032308B2 (en) * 2008-03-13 2011-10-04 Siemens Medical Solutions Usa, Inc. Modeling lung cancer survival probability after or side-effects from therapy
WO2009126553A2 (en) * 2008-04-08 2009-10-15 The Quantum Group, Inc. Dynamic integration of disparate health-related processes and data
US8412542B2 (en) * 2008-04-25 2013-04-02 Peoplechart Corporation Scoring system for monitoring or measuring adherence in medical treatment
US20090313045A1 (en) * 2008-06-11 2009-12-17 Boyce Mark D System and Method for Medical Research and Clinical Trial
US20100010320A1 (en) * 2008-07-07 2010-01-14 Perkins David G Mobile medical workstation and a temporarily associating mobile computing device
US20100017231A1 (en) * 2008-07-17 2010-01-21 Archie Galbraith Active Patient Management
US8078554B2 (en) 2008-09-03 2011-12-13 Siemens Medical Solutions Usa, Inc. Knowledge-based interpretable predictive model for survival analysis
RU2533500C2 (ru) * 2008-09-26 2014-11-20 Конинклейке Филипс Электроникс, Н.В. Система и способ для объединения клинических признаков и признаков изображений для диагностики с применением компьютера
US9123095B2 (en) * 2008-09-29 2015-09-01 Koninklijke Philips N.V. Method for increasing the robustness of computer-aided diagnosis to image processing uncertainties
US20100082506A1 (en) * 2008-09-30 2010-04-01 General Electric Company Active Electronic Medical Record Based Support System Using Learning Machines
US20100082371A1 (en) * 2008-10-01 2010-04-01 General Electric Company, A New York Corporation Patient Document Privacy And Disclosure Engine
EP2338121A1 (en) * 2008-10-10 2011-06-29 Koninklijke Philips Electronics N.V. Health-risk metric determination and/or presentation
US8649577B1 (en) 2008-11-30 2014-02-11 Image Analysis, Inc. Automatic method and system for measurements of bone density and structure of the hip from 3-D X-ray imaging devices
US20100169115A1 (en) * 2008-12-31 2010-07-01 Tamis Robert H System for matching individuals with health care providers and methods thereof
US8560346B2 (en) 2009-01-05 2013-10-15 Siemens Medical Solutions Usa, Inc. System and method for ranking quality improvement factors in patient care
US8685093B2 (en) 2009-01-23 2014-04-01 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8126736B2 (en) 2009-01-23 2012-02-28 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8250026B2 (en) * 2009-03-06 2012-08-21 Peoplechart Corporation Combining medical information captured in structured and unstructured data formats for use or display in a user application, interface, or view
WO2010108092A2 (en) * 2009-03-19 2010-09-23 Phenotypeit, Inc. Medical health information system
EP2411948A1 (en) * 2009-03-24 2012-02-01 Performance Clinical Systems, LLC Method for selecting custom order hospitalization sets
JP5501445B2 (ja) 2009-04-30 2014-05-21 ペイシェンツライクミー， インコーポレイテッド オンラインコミュニティ内のデータ提出を促進するシステムおよび方法
US8346369B2 (en) * 2009-05-14 2013-01-01 Cardiac Pacemakers, Inc. Systems and methods for programming implantable medical devices
US20110010195A1 (en) * 2009-07-08 2011-01-13 Steven Charles Cohn Medical history system
US20110202486A1 (en) * 2009-07-21 2011-08-18 Glenn Fung Healthcare Information Technology System for Predicting Development of Cardiovascular Conditions
US20110022981A1 (en) * 2009-07-23 2011-01-27 Deepa Mahajan Presentation of device utilization and outcome from a patient management system
US8139822B2 (en) * 2009-08-28 2012-03-20 Allen Joseph Selner Designation of a characteristic of a physical capability by motion analysis, systems and methods
US20110054289A1 (en) * 2009-09-01 2011-03-03 Adidas AG, World of Sports Physiologic Database And System For Population Modeling And Method of Population Modeling
US8731966B2 (en) * 2009-09-24 2014-05-20 Humedica, Inc. Systems and methods for real-time data ingestion to a clinical analytics platform to generate a heat map
US20220139561A1 (en) * 2009-09-25 2022-05-05 Volcano Corporation Device and Method for Determining the Likelihood of a Patient Having a Clinical Event or a Clinically Silent Event Based on Ascertained Physiological Parameters
US8751495B2 (en) * 2009-09-29 2014-06-10 Siemens Medical Solutions Usa, Inc. Automated patient/document identification and categorization for medical data
US8930389B2 (en) * 2009-10-06 2015-01-06 International Business Machines Corporation Mutual search and alert between structured and unstructured data stores
US20110106558A1 (en) * 2009-11-02 2011-05-05 Cerner Innovation, Inc. Infection control solution
CN103003817A (zh) * 2009-12-10 2013-03-27 皇家飞利浦电子股份有限公司 临床数据的自动化注释
US20110166873A1 (en) * 2009-12-31 2011-07-07 Cerner Innovation, Inc. Patient-specific research consent manager
CA2728831A1 (en) * 2010-01-22 2011-07-22 Lifescan, Inc. Diabetes management unit, method, and system
US20110184761A1 (en) * 2010-01-25 2011-07-28 Siemens Medical Solutions Usa, Inc. Method and Apparatus for Estimating Patient Populations
WO2011100577A2 (en) * 2010-02-12 2011-08-18 Procure Treatment Centers, Inc. Robotic mobile anesthesia system
US20110238438A1 (en) * 2010-03-25 2011-09-29 Numoda Technologies, Inc. Automated method of graphically displaying predicted patient enrollment in a clinical trial study
US10943676B2 (en) 2010-06-08 2021-03-09 Cerner Innovation, Inc. Healthcare information technology system for predicting or preventing readmissions
US8914319B2 (en) * 2010-06-15 2014-12-16 The Regents Of The University Of Michigan Personalized health risk assessment for critical care
US8990135B2 (en) 2010-06-15 2015-03-24 The Regents Of The University Of Michigan Personalized health risk assessment for critical care
US9138143B2 (en) 2010-08-17 2015-09-22 Fujitsu Limited Annotating medical data represented by characteristic functions
US8874607B2 (en) * 2010-08-17 2014-10-28 Fujitsu Limited Representing sensor data as binary decision diagrams
US20120046966A1 (en) * 2010-08-19 2012-02-23 International Business Machines Corporation Health Management Application Development and Deployment Framework
US10580520B2 (en) 2010-09-01 2020-03-03 Apixio, Inc. Systems and methods for customized annotation of medical information
US11694239B2 (en) 2010-09-01 2023-07-04 Apixio, Inc. Method of optimizing patient-related outcomes
US20130262144A1 (en) 2010-09-01 2013-10-03 Imran N. Chaudhri Systems and Methods for Patient Retention in Network Through Referral Analytics
US11955238B2 (en) 2010-09-01 2024-04-09 Apixio, Llc Systems and methods for determination of patient true state for personalized medicine
US11538561B2 (en) 2010-09-01 2022-12-27 Apixio, Inc. Systems and methods for medical information data warehouse management
US11481411B2 (en) 2010-09-01 2022-10-25 Apixio, Inc. Systems and methods for automated generation classifiers
US10629303B2 (en) 2010-09-01 2020-04-21 Apixio, Inc. Systems and methods for determination of patient true state for personalized medicine
US11610653B2 (en) 2010-09-01 2023-03-21 Apixio, Inc. Systems and methods for improved optical character recognition of health records
US9043901B2 (en) * 2010-09-01 2015-05-26 Apixio, Inc. Intent-based clustering of medical information
US11195213B2 (en) 2010-09-01 2021-12-07 Apixio, Inc. Method of optimizing patient-related outcomes
US10614915B2 (en) 2010-09-01 2020-04-07 Apixio, Inc. Systems and methods for determination of patient true state for risk management
US11544652B2 (en) 2010-09-01 2023-01-03 Apixio, Inc. Systems and methods for enhancing workflow efficiency in a healthcare management system
BR112013005215A2 (pt) * 2010-09-07 2016-04-26 Konink Philips Eletronics N V método e sistema
US11398310B1 (en) 2010-10-01 2022-07-26 Cerner Innovation, Inc. Clinical decision support for sepsis
US10734115B1 (en) 2012-08-09 2020-08-04 Cerner Innovation, Inc Clinical decision support for sepsis
US10431336B1 (en) 2010-10-01 2019-10-01 Cerner Innovation, Inc. Computerized systems and methods for facilitating clinical decision making
US11348667B2 (en) 2010-10-08 2022-05-31 Cerner Innovation, Inc. Multi-site clinical decision support
US8666773B1 (en) 2010-11-19 2014-03-04 Hospitalists Now, Inc. System and method for maintaining hospitalist and patient information
US10460078B2 (en) 2010-12-03 2019-10-29 Parallel 6, Inc. Systems and methods for remote demand based data management of clinical locations
RU2585419C2 (ru) * 2010-12-20 2016-05-27 Конинклейке Филипс Электроникс Н.В. Система и способ автоматической генерации исходных планов лучевой терапии
US11141063B2 (en) * 2010-12-23 2021-10-12 Philips Image Guided Therapy Corporation Integrated system architectures and methods of use
US20120171650A1 (en) * 2010-12-29 2012-07-05 Warner Adrian F Methods and systems for developing medical waveforms and training methods
US10628553B1 (en) 2010-12-30 2020-04-21 Cerner Innovation, Inc. Health information transformation system
US20120173475A1 (en) * 2010-12-30 2012-07-05 Cerner Innovation, Inc. Health Information Transformation System
US9111018B2 (en) 2010-12-30 2015-08-18 Cerner Innovation, Inc Patient care cards
CN102178511A (zh) * 2011-04-11 2011-09-14 Tcl集团股份有限公司 疾病预防提示系统及其实现方法
US20120316898A1 (en) * 2011-06-08 2012-12-13 Levitt Tod S Scalable determination of probable patient eligibility for clinical trials and associated process for active solicitation of patients for clinical trials via their healthcare providers
US9286035B2 (en) 2011-06-30 2016-03-15 Infosys Limited Code remediation
US8517608B1 (en) 2011-08-03 2013-08-27 Ben A. Arnold System and method for calibration of CT scanners and display of images in density units without the use of water phantoms
US10198499B1 (en) * 2011-08-08 2019-02-05 Cerner Innovation, Inc. Synonym discovery
US8599009B2 (en) 2011-08-16 2013-12-03 Elwha Llc Systematic distillation of status data relating to regimen compliance
CN102945235A (zh) * 2011-08-16 2013-02-27 句容今太科技园有限公司 面向医疗保险违规和欺诈行为的数据挖掘系统
US9311219B2 (en) * 2011-09-29 2016-04-12 Siemens Aktiengesellschaft Automatic trace retrieval using semantic bridge
US8856156B1 (en) 2011-10-07 2014-10-07 Cerner Innovation, Inc. Ontology mapper
US20130124217A1 (en) * 2011-11-11 2013-05-16 Debra Thesman Health plan rating system improvement program
CN103999086B (zh) 2011-12-13 2018-10-26 皇家飞利浦有限公司 将书面临床指南转换成计算机可解读指南的系统与方法
KR101855179B1 (ko) * 2011-12-21 2018-05-09 삼성전자 주식회사 질환 진단을 위한 최적의 진단 요소 셋 결정 장치 및 방법
US10528913B2 (en) 2011-12-30 2020-01-07 Elwha Llc Evidence-based healthcare information management protocols
US20130173298A1 (en) 2011-12-30 2013-07-04 Elwha LLC, a limited liability company of State of Delaware Evidence-based healthcare information management protocols
US10679309B2 (en) 2011-12-30 2020-06-09 Elwha Llc Evidence-based healthcare information management protocols
US11244029B1 (en) 2011-12-30 2022-02-08 RxANTE, INC. Healthcare management system and method
US10475142B2 (en) 2011-12-30 2019-11-12 Elwha Llc Evidence-based healthcare information management protocols
US10559380B2 (en) 2011-12-30 2020-02-11 Elwha Llc Evidence-based healthcare information management protocols
US10552581B2 (en) 2011-12-30 2020-02-04 Elwha Llc Evidence-based healthcare information management protocols
US10340034B2 (en) 2011-12-30 2019-07-02 Elwha Llc Evidence-based healthcare information management protocols
US20130191157A1 (en) * 2012-01-17 2013-07-25 Optuminsight, Inc. Unified healthcare intelligence, analytics, and care management
US10372741B2 (en) 2012-03-02 2019-08-06 Clarabridge, Inc. Apparatus for automatic theme detection from unstructured data
CN104205105B (zh) * 2012-03-30 2018-08-17 皇家飞利浦有限公司 用于将计算机可解读指南引擎的状态与患者护理的状态同步的方法
US8930223B2 (en) * 2012-03-30 2015-01-06 International Business Machines Corporation Patient cohort matching
US10249385B1 (en) 2012-05-01 2019-04-02 Cerner Innovation, Inc. System and method for record linkage
US9298764B2 (en) * 2012-05-23 2016-03-29 Oracle International Corporation Partial source verification of EDC data
US9075796B2 (en) * 2012-05-24 2015-07-07 International Business Machines Corporation Text mining for large medical text datasets and corresponding medical text classification using informative feature selection
US20130332190A1 (en) * 2012-06-06 2013-12-12 Cerner Innovation, Inc. Providing indications of clinical-trial criteria modifications
US20140025390A1 (en) * 2012-07-21 2014-01-23 Michael Y. Shen Apparatus and Method for Automated Outcome-Based Process and Reference Improvement in Healthcare
US20140058738A1 (en) * 2012-08-21 2014-02-27 International Business Machines Corporation Predictive analysis for a medical treatment pathway
US10593426B2 (en) 2012-09-13 2020-03-17 Parkland Center For Clinical Innovation Holistic hospital patient care and management system and method for automated facial biological recognition
US10496788B2 (en) 2012-09-13 2019-12-03 Parkland Center For Clinical Innovation Holistic hospital patient care and management system and method for automated patient monitoring
US20140081659A1 (en) 2012-09-17 2014-03-20 Depuy Orthopaedics, Inc. Systems and methods for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking
US20140089004A1 (en) * 2012-09-27 2014-03-27 University Of Utah Research Foundation Patient cohort laboratory result prediction
US20140088989A1 (en) 2012-09-27 2014-03-27 Balaji Krishnapuram Rapid Learning Community for Predictive Models of Medical Knowledge
US10403391B2 (en) 2012-09-28 2019-09-03 Cerner Health Services, Inc. Automated mapping of service codes in healthcare systems
US10403403B2 (en) * 2012-09-28 2019-09-03 Cerner Innovation, Inc. Adaptive medical documentation system
US10565315B2 (en) 2012-09-28 2020-02-18 Cerner Innovation, Inc. Automated mapping of service codes in healthcare systems
US10318635B2 (en) 2012-09-28 2019-06-11 Cerner Innovation, Inc. Automated mapping of service codes in healthcare systems
US20140095204A1 (en) * 2012-09-28 2014-04-03 Siemens Medical Solutions Usa, Inc. Automated medical cohort determination
JP2015533437A (ja) * 2012-10-19 2015-11-24 アピシオ，インク． 識別不能化および再識別を用いた医療情報解析のためのシステムおよび方法
US20140149132A1 (en) * 2012-11-27 2014-05-29 Jan DeHaan Adaptive medical documentation and document management
US10424403B2 (en) 2013-01-28 2019-09-24 Siemens Aktiengesellschaft Adaptive medical documentation system
US10946311B1 (en) 2013-02-07 2021-03-16 Cerner Innovation, Inc. Discovering context-specific serial health trajectories
US11894117B1 (en) 2013-02-07 2024-02-06 Cerner Innovation, Inc. Discovering context-specific complexity and utilization sequences
US10769241B1 (en) 2013-02-07 2020-09-08 Cerner Innovation, Inc. Discovering context-specific complexity and utilization sequences
WO2014145705A2 (en) 2013-03-15 2014-09-18 Battelle Memorial Institute Progression analytics system
SG11201507611UA (en) 2013-03-15 2015-10-29 Synaptive Medical Barbados Inc Intramodal synchronization of surgical data
JP2014215935A (ja) * 2013-04-30 2014-11-17 富士通株式会社 情報処理方法、装置及びプログラム
US20140343955A1 (en) * 2013-05-16 2014-11-20 Verizon Patent And Licensing Inc. Method and apparatus for providing a predictive healthcare service
JP6059800B2 (ja) * 2013-05-20 2017-01-11 株式会社日立製作所 ヘルスケア情報処理システム
US11183300B2 (en) 2013-06-05 2021-11-23 Nuance Communications, Inc. Methods and apparatus for providing guidance to medical professionals
EP3000064A1 (en) * 2013-06-05 2016-03-30 Nuance Communications, Inc. Methods and apparatus for providing guidance to medical professionals
US20140365242A1 (en) * 2013-06-07 2014-12-11 Siemens Medical Solutions Usa, Inc. Integration of Multiple Input Data Streams to Create Structured Data
WO2014201515A1 (en) * 2013-06-18 2014-12-24 Deakin University Medical data processing for risk prediction
EP3016060A4 (en) * 2013-06-28 2016-05-18 Hitachi Ltd SYSTEM FOR ANALYZING MEDICAL CARE PROCESSES
US10540448B2 (en) 2013-07-15 2020-01-21 Cerner Innovation, Inc. Gap in care determination using a generic repository for healthcare
CA2918332C (en) * 2013-07-18 2023-08-08 Parkland Center For Clinical Innovation Patient care surveillance system and method
US20150025908A1 (en) * 2013-07-19 2015-01-22 Hewlett-Packard Development Company, L.P. Clustering and analysis of electronic medical records
US20150039334A1 (en) * 2013-08-02 2015-02-05 Optum, Inc. Claim-centric grouper analysis
US11581092B1 (en) 2013-08-12 2023-02-14 Cerner Innovation, Inc. Dynamic assessment for decision support
US10483003B1 (en) 2013-08-12 2019-11-19 Cerner Innovation, Inc. Dynamically determining risk of clinical condition
US20150081336A1 (en) * 2013-09-19 2015-03-19 Quintiles Transnational Corporation Electrical Computing Devices for Quantification of Differences in Medical Treatment Populations
US20150100344A1 (en) * 2013-10-08 2015-04-09 Chen Technology, Inc. Patient health information analysis system
US11610677B2 (en) * 2013-10-08 2023-03-21 Chen Technology, Inc. Patient health monitoring system
US20160239619A1 (en) * 2013-10-14 2016-08-18 Koninklijke Philips N.V. A unique methodology combining user roles and context aware algorithms for presenting clinical information, audio, video and communication controls to safely capture caregiver attention, reduce information overload, and optimize workflow and decision support
US20160292366A1 (en) * 2013-11-12 2016-10-06 Ecbig (E-Commerce & Business Integration) Aps System and method of combining medicinal product information of medicaments
CN104657925A (zh) * 2013-11-25 2015-05-27 北大医疗信息技术有限公司 病历文档的显示装置和病历文档的显示方法
US20150149235A1 (en) * 2013-11-27 2015-05-28 General Electric Company Methods and systems to improve a quality of data employed by a healthcare analytics system
US10366780B2 (en) 2014-01-24 2019-07-30 Elligo Health Research, Inc. Predictive patient to medical treatment matching system and method
AU2015210999A1 (en) 2014-01-29 2016-07-21 Otsuka Pharmaceutical Co., Ltd. Device-based risk management of a therapeutic
US9672256B2 (en) 2014-02-04 2017-06-06 Microsoft Technology Licensing, Llc Creating data views
US20170091406A1 (en) * 2014-03-17 2017-03-30 Eqol Inc. System and method for managing illness outside of a hospital environment
CO6930061A1 (es) * 2014-04-08 2014-04-28 Pontificia Universidad Javeriana Método de priorización de historias clínicas electrónicas para estudios retrospectivos
CN104063579B (zh) * 2014-05-16 2017-08-15 上海亿保健康管理有限公司 基于多元医疗消费数据的健康动态预测方法和设备
CN104035980B (zh) * 2014-05-26 2017-08-04 王和平 一种面向结构化医药信息的检索方法和系统
US10529445B2 (en) * 2014-06-13 2020-01-07 University Hospitals Of Cleveland Graphical user interface for tracking and displaying patient information over the course of care
US11437125B2 (en) 2014-06-13 2022-09-06 University Hospitals Cleveland Medical Center Artificial-intelligence-based facilitation of healthcare delivery
EP3943611A3 (en) 2014-06-24 2022-05-04 Likeminds, Inc. Predictive neurodiagnostic methods
US10755369B2 (en) 2014-07-16 2020-08-25 Parkland Center For Clinical Innovation Client management tool system and method
CN104077495B (zh) * 2014-07-17 2017-10-17 杜晓松 一种可穿戴无线人体特征信息采集及传输模块、监控系统
WO2016012040A1 (de) * 2014-07-23 2016-01-28 Siemens Aktiengesellschaft Verfahren und datenverarbeitungssystem zur datenerhebung für eine klinische studie
JP6759201B2 (ja) 2014-08-07 2020-09-23 キュアレーター， インコーポレイテッド 慢性疾患の発見および管理システム
RU2699607C2 (ru) * 2014-08-12 2019-09-06 Конинклейке Филипс Н.В. Повышение эффективности и уменьшение частоты последующих лучевых исследований путем прогнозирования основания для следующего исследования
US10192639B2 (en) 2014-08-22 2019-01-29 Drfirst.Com, Inc. Method and system for medical suggestion search
US11232855B2 (en) 2014-09-23 2022-01-25 Airstrip Ip Holdings, Llc Near-real-time transmission of serial patient data to third-party systems
WO2016048619A1 (en) * 2014-09-23 2016-03-31 Airstrip Ip Holdings, Llc Near-real-time transmission of serial patient data to third-party systems
TW201612790A (en) * 2014-09-29 2016-04-01 Chunghwa Telecom Co Ltd Method of increasing effectiveness of information security risk assessment and risk recognition
US20160147960A1 (en) * 2014-11-25 2016-05-26 Electronics And Telecommunications Research Institute Apparatus and method for providing customized personal health service
US9747654B2 (en) 2014-12-09 2017-08-29 Cerner Innovation, Inc. Virtual home safety assessment framework
WO2016092411A1 (en) * 2014-12-09 2016-06-16 Koninklijke Philips N.V. System and method for uniformly correlating unstructured entry features to associated therapy features
US20160188811A1 (en) * 2014-12-31 2016-06-30 Cerner Innovation, Inc. Clinical trial management
US20170103182A1 (en) * 2015-01-25 2017-04-13 International Business Machines Corporation Modelling Disease Progression and Intervention Effects Using Non-Clinical Information Proxies for Clinical Information
US11275757B2 (en) 2015-02-13 2022-03-15 Cerner Innovation, Inc. Systems and methods for capturing data, creating billable information and outputting billable information
US10120976B2 (en) * 2015-04-08 2018-11-06 Oracle International Corporation Methods, systems, and computer readable media for integrating medical imaging data in a data warehouse
CN104881463B (zh) * 2015-05-22 2018-01-16 清华大学深圳研究生院 基于结构化病历数据库的参考病历检索方法及装置
US20190013093A1 (en) * 2015-07-21 2019-01-10 Arizona Board Of Regents On Behalf Of The University Of Arizona Systems and methods for analyzing healthcare data
US20180226141A1 (en) * 2015-07-21 2018-08-09 Arizona Board Of Regents On Behalf Of The University Of Arizona Patient coordination system and method
US10825557B2 (en) 2015-09-04 2020-11-03 Canon Medical Systems Corporation Medical information processing apparatus
US10665331B2 (en) 2015-10-29 2020-05-26 Accenture Global Services Limited Device-based participant matching
US10199126B2 (en) 2015-11-12 2019-02-05 Vivante Health, Inc. Systems and methods for developing individualized health improvement plans
US10546654B2 (en) * 2015-12-17 2020-01-28 Drfirst.Com, Inc. Method and system for intelligent completion of medical record based on big data analytics
US9928230B1 (en) 2016-09-29 2018-03-27 Vignet Incorporated Variable and dynamic adjustments to electronic forms
US9858063B2 (en) 2016-02-10 2018-01-02 Vignet Incorporated Publishing customized application modules
CN107169257A (zh) * 2016-03-07 2017-09-15 刘江 基于视觉影像的多眼疾“慧查”筛查方法和系统
RU2664150C2 (ru) * 2016-05-05 2018-08-15 Ян Львович Габинский Коронарный паспорт человека
US10372822B2 (en) * 2016-06-03 2019-08-06 International Business Machines Corporation Automated timeline completion using event progression knowledge base
US10909129B2 (en) * 2016-07-15 2021-02-02 Koninklijke Philips N.V. Automated identification of salient finding codes in structured and narrative reports
CN106228020A (zh) * 2016-07-29 2016-12-14 广州天健软件有限公司 一种呼吸道疾病的临床数据支撑系统
CN106228023B (zh) * 2016-08-01 2018-08-28 清华大学 一种基于本体和主题模型的临床路径挖掘方法
CN109564780B (zh) * 2016-08-08 2023-11-03 赛因特凯亚控股公司 照护计划制作支援系统及方法、以及存储介质
US10755804B2 (en) 2016-08-10 2020-08-25 Talix, Inc. Health information system for searching, analyzing and annotating patient data
CN107870376A (zh) * 2016-09-28 2018-04-03 南京南瑞继保电气有限公司 一种多源气象数据二次采样整合方法
US11177022B2 (en) 2016-10-17 2021-11-16 International Business Machines Corporation Workflow for automatic measurement of doppler pipeline
US11069432B2 (en) 2016-10-17 2021-07-20 International Business Machines Corporation Automatic disease detection from unstructured textual reports
US11195600B2 (en) 2016-10-17 2021-12-07 International Business Machines Corporation Automatic discrepancy detection in medical data
CN108091398B (zh) * 2016-11-21 2022-03-04 医渡云（北京）技术有限公司 患者分组方法及装置
KR101869438B1 (ko) * 2016-11-22 2018-06-20 네이버 주식회사 딥 러닝을 이용하여 환자의 진단 이력으로부터 질병 예후를 예측하는 방법 및 시스템
CN106777002B (zh) * 2016-12-07 2020-10-30 华北理工大学 一种基于数据挖掘的医学知识库系统
US10192640B2 (en) 2017-03-01 2019-01-29 Siemens Healthcare Gmbh Fractional flow reserve decision support system
JP6940088B2 (ja) * 2017-03-07 2021-09-22 株式会社ジェイマックシステム 治療実績評価支援装置、治療実績評価支援方法、および治療実績評価支援プログラム
US10825167B2 (en) 2017-04-28 2020-11-03 Siemens Healthcare Gmbh Rapid assessment and outcome analysis for medical patients
CN109949921A (zh) * 2017-05-09 2019-06-28 北京华信诚达科技有限公司 一种远程评估系统性红斑狼疮患者心脏功能的系统
CN107085664A (zh) * 2017-05-16 2017-08-22 中国医学科学院北京协和医院 用于急性冠脉综合征筛选分析的病历数据挖掘
EP3634213A4 (en) * 2017-06-09 2021-04-07 Curelator, Inc. SYSTEMS AND METHODS FOR VISUALIZATION OF COMPARISON OF DISEASE SYMPTOMS OF A PATIENT POPULATION
JP6262908B1 (ja) * 2017-06-09 2018-01-17 リーズンホワイ株式会社 医療システム及び医療プログラム
US11410756B2 (en) * 2017-07-28 2022-08-09 Google Llc System and method for predicting and summarizing medical events from electronic health records
CN107480295B (zh) * 2017-08-29 2019-11-15 北斗云谷（北京）科技有限公司 用户数据的修正方法
WO2019055879A2 (en) * 2017-09-15 2019-03-21 PatientsLikeMe Inc. SYSTEMS AND METHODS FOR COLLECTING AND ANALYZING COMPLETE MEDICAL INFORMATION
EP3692494A4 (en) * 2017-10-03 2021-06-30 Infinite Computer Solutions Inc. DATA AGGREGATION IN HEALTH CARE SYSTEMS
JP6953270B2 (ja) * 2017-10-19 2021-10-27 キヤノンメディカルシステムズ株式会社 病院情報システム、及び薬剤提案選出プログラム
US10629305B2 (en) * 2017-11-09 2020-04-21 General Electric Company Methods and apparatus for self-learning clinical decision support
JP2019091324A (ja) * 2017-11-16 2019-06-13 コニカミノルタ株式会社 医療情報処理装置及びプログラム
US20190156923A1 (en) 2017-11-17 2019-05-23 LunaPBC Personal, omic, and phenotype data community aggregation platform
US20190180872A1 (en) * 2017-12-12 2019-06-13 International Business Machines Corporation Second Opinion Decision Support Using Patient Electronic Medical Records
US10650928B1 (en) 2017-12-18 2020-05-12 Clarify Health Solutions, Inc. Computer network architecture for a pipeline of models for healthcare outcomes with machine learning and artificial intelligence
US11605018B2 (en) 2017-12-27 2023-03-14 Cerner Innovation, Inc. Ontology-guided reconciliation of electronic records
EP3756189A4 (en) * 2018-01-22 2021-09-29 Cancer Commons PLATFORMS TO PERFORM VIRTUAL TESTS
US20190374157A1 (en) * 2018-06-07 2019-12-12 Ryan McGinnis Methods and apparatus for providing personalized biofeedback for the treatment of panic attacks
US10811139B1 (en) 2018-06-13 2020-10-20 Clarify Health Solutions, Inc. Computer network architecture with machine learning and artificial intelligence and dynamic patient guidance
US10970089B2 (en) 2018-06-28 2021-04-06 Radiology Partners, Inc. User interface for determining real-time changes to content entered into the user interface to provide to a classifier program and rules engine to generate results for the content
US11456082B2 (en) 2018-07-03 2022-09-27 International Business Machines Corporation Patient engagement communicative strategy recommendation
CN109192318A (zh) * 2018-07-11 2019-01-11 辽宁石油化工大学 描述传染病传播过程的简化SIS模型的建立与Laplace分析
US11315686B2 (en) 2018-08-07 2022-04-26 Vivante Health, Inc. Individualized care management system based on digestive activity
US10775974B2 (en) 2018-08-10 2020-09-15 Vignet Incorporated User responsive dynamic architecture
US11763950B1 (en) 2018-08-16 2023-09-19 Clarify Health Solutions, Inc. Computer network architecture with machine learning and artificial intelligence and patient risk scoring
WO2020047171A1 (en) * 2018-08-28 2020-03-05 Neurospring Medical device and method for diagnosis and treatment of disease
JP7124879B2 (ja) * 2018-10-05 2022-08-24 日本電気株式会社 マッチング支援装置、マッチング支援方法、プログラム
US10943681B2 (en) * 2018-11-21 2021-03-09 Enlitic, Inc. Global multi-label generating system
CN109637669B (zh) * 2018-11-22 2023-07-18 中山大学 基于深度学习的治疗方案的生成方法、装置及存储介质
KR102216689B1 (ko) * 2018-11-23 2021-02-17 네이버 주식회사 시계열 의료 데이터를 통한 질병 예후 예측을 위한 딥 뉴럴 네트워크의 분류 결과 시각화 방법 및 시스템
US11894139B1 (en) 2018-12-03 2024-02-06 Patientslikeme Llc Disease spectrum classification
US10930386B2 (en) * 2018-12-11 2021-02-23 International Business Machines Corporation Automated normality scoring of echocardiograms
US11410650B1 (en) 2018-12-26 2022-08-09 Cerner Innovation, Inc. Semantically augmented clinical speech processing
WO2020139379A1 (en) 2018-12-28 2020-07-02 LunaPBC Community data aggregation, completion, correction, and use
CN109830302B (zh) * 2019-01-28 2021-04-06 北京交通大学 用药模式挖掘方法、装置和电子设备
JP7302200B2 (ja) * 2019-02-26 2023-07-04 富士フイルムビジネスイノベーション株式会社 情報処理装置及びプログラム
US11625789B1 (en) 2019-04-02 2023-04-11 Clarify Health Solutions, Inc. Computer network architecture with automated claims completion, machine learning and artificial intelligence
US11348689B1 (en) 2019-04-04 2022-05-31 Hospitalists Now, Inc. Method for analyzing diagnoses, and determining and reporting working diagnosis related data using standardized patient medical information
US11621085B1 (en) 2019-04-18 2023-04-04 Clarify Health Solutions, Inc. Computer network architecture with machine learning and artificial intelligence and active updates of outcomes
US11238469B1 (en) 2019-05-06 2022-02-01 Clarify Health Solutions, Inc. Computer network architecture with machine learning and artificial intelligence and risk adjusted performance ranking of healthcare providers
CN110223784A (zh) * 2019-06-17 2019-09-10 无码科技（杭州）有限公司 临床试验患者匹配方法
CN110349652B (zh) * 2019-07-12 2022-02-22 之江实验室 一种融合结构化影像数据的医疗数据分析系统
US10726359B1 (en) 2019-08-06 2020-07-28 Clarify Health Solutions, Inc. Computer network architecture with machine learning and artificial intelligence and automated scalable regularization
US11645344B2 (en) 2019-08-26 2023-05-09 Experian Health, Inc. Entity mapping based on incongruent entity data
CN110517769B (zh) * 2019-08-29 2022-10-14 西安交通大学医学院第一附属医院 预测不稳定型心绞痛患者是否需要植入冠脉支架的设备
WO2021044594A1 (en) * 2019-09-05 2021-03-11 Hitachi, Ltd. Method, system, and apparatus for health status prediction
US10643751B1 (en) 2019-09-26 2020-05-05 Clarify Health Solutions, Inc. Computer network architecture with benchmark automation, machine learning and artificial intelligence for measurement factors
US10643749B1 (en) 2019-09-30 2020-05-05 Clarify Health Solutions, Inc. Computer network architecture with machine learning and artificial intelligence and automated insight generation
KR102340813B1 (ko) * 2019-10-15 2021-12-16 노서규 소셜 네트워크 기반의 환자의 증상관리 및 증상완화 방법 및 시스템
US11270785B1 (en) * 2019-11-27 2022-03-08 Clarify Health Solutions, Inc. Computer network architecture with machine learning and artificial intelligence and care groupings
US11675805B2 (en) 2019-12-16 2023-06-13 Cerner Innovation, Inc. Concept agnostic reconcilation and prioritization based on deterministic and conservative weight methods
US11730420B2 (en) 2019-12-17 2023-08-22 Cerner Innovation, Inc. Maternal-fetal sepsis indicator
JP2021111248A (ja) * 2020-01-15 2021-08-02 キヤノンメディカルシステムズ株式会社 治験マッチング装置
US11328796B1 (en) 2020-02-25 2022-05-10 Vignet Incorporated Techniques for selecting cohorts for decentralized clinical trials for pharmaceutical research
US11605038B1 (en) 2020-05-18 2023-03-14 Vignet Incorporated Selecting digital health technology to achieve data collection compliance in clinical trials
US11461216B1 (en) 2020-05-18 2022-10-04 Vignet Incorporated Monitoring and improving data collection using digital health technology
US20220020481A1 (en) 2020-07-20 2022-01-20 Abbott Laboratories Digital pass verification systems and methods
US11763919B1 (en) 2020-10-13 2023-09-19 Vignet Incorporated Platform to increase patient engagement in clinical trials through surveys presented on mobile devices
CA3196643A1 (en) * 2020-10-27 2022-05-05 Jacob L. GLASS Patient-specific therapeutic predictions through analysis of free text and structured patient records
US20220139514A1 (en) * 2020-11-03 2022-05-05 Nuance Communications, Inc. Communication System and Method
US11417418B1 (en) 2021-01-11 2022-08-16 Vignet Incorporated Recruiting for clinical trial cohorts to achieve high participant compliance and retention
US11240329B1 (en) 2021-01-29 2022-02-01 Vignet Incorporated Personalizing selection of digital programs for patients in decentralized clinical trials and other health research
US11361846B1 (en) 2021-02-03 2022-06-14 Vignet Incorporated Systems and methods for customizing monitoring programs involving remote devices
US11521714B1 (en) 2021-02-03 2022-12-06 Vignet Incorporated Increasing diversity of participants in health research using adaptive methods
US11316941B1 (en) 2021-02-03 2022-04-26 Vignet Incorporated Remotely managing and adapting monitoring programs using machine learning predictions
US11296971B1 (en) 2021-02-03 2022-04-05 Vignet Incorporated Managing and adapting monitoring programs
US11281553B1 (en) 2021-04-16 2022-03-22 Vignet Incorporated Digital systems for enrolling participants in health research and decentralized clinical trials
US11789837B1 (en) 2021-02-03 2023-10-17 Vignet Incorporated Adaptive data collection in clinical trials to increase the likelihood of on-time completion of a trial
US11196656B1 (en) 2021-02-03 2021-12-07 Vignet Incorporated Improving diversity in cohorts for health research
US11586524B1 (en) 2021-04-16 2023-02-21 Vignet Incorporated Assisting researchers to identify opportunities for new sub-studies in digital health research and decentralized clinical trials
US11636500B1 (en) 2021-04-07 2023-04-25 Vignet Incorporated Adaptive server architecture for controlling allocation of programs among networked devices
US20220353463A1 (en) * 2021-05-03 2022-11-03 Udo, LLC Two-way camera operation
US11393566B1 (en) 2021-07-13 2022-07-19 Beigene, Ltd. Interoperable platform for reducing redundancy in medical database management
JP7121841B1 (ja) 2021-08-26 2022-08-18 Ｅｐｓホールディングス株式会社 臨床試験支援端末、臨床試験支援方法及び臨床試験支援プログラム
US11901083B1 (en) 2021-11-30 2024-02-13 Vignet Incorporated Using genetic and phenotypic data sets for drug discovery clinical trials
US11705230B1 (en) 2021-11-30 2023-07-18 Vignet Incorporated Assessing health risks using genetic, epigenetic, and phenotypic data sources
JP2023163823A (ja) * 2022-04-28 2023-11-10 国立大学法人東北大学 情報処理システム
WO2023217737A1 (en) 2022-05-11 2023-11-16 Symptoma Gmbh Health data enrichment for improved medical diagnostics

Family Cites Families (172)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US567255A (en) * 1896-09-08 Michael p
US5669877A (en) 1994-03-07 1997-09-23 Sims Deltec, Inc. Systems and methods for automated testing of medical equipment
US4946679A (en) * 1988-07-25 1990-08-07 Thys Jacobs Susan Method for the treatment of premenstrual syndrome
EP0542717B1 (en) 1988-12-20 1997-02-12 Nippon Steel Corporation Blast furnace operation management method and apparatus
US5508912A (en) 1989-01-23 1996-04-16 Barry Schneiderman Clinical database of classified out-patients for tracking primary care outcome
JP2955873B2 (ja) * 1989-08-10 1999-10-04 富士写真フイルム株式会社 画像処理装置
CA2081571C (en) 1990-05-01 1998-09-15 Nancy A. K. Perkins Health care services comparison processing
JP3006724B2 (ja) * 1991-02-22 2000-02-07 ソニー株式会社 取付装置
US5544044A (en) * 1991-08-02 1996-08-06 United Healthcare Corporation Method for evaluation of health care quality
GB9117015D0 (en) * 1991-08-07 1991-09-18 Software Solutions Ltd Operation of computer systems
US5359509A (en) * 1991-10-31 1994-10-25 United Healthcare Corporation Health care payment adjudication and review system
US5307262A (en) 1992-01-29 1994-04-26 Applied Medical Data, Inc. Patient data quality review method and system
EP0596247A3 (en) 1992-11-02 1994-10-12 Motorola Inc Method for creating a complete document index, as well as for searching, retrieving and viewing.
US6196970B1 (en) * 1999-03-22 2001-03-06 Stephen J. Brown Research data collection and analysis
US5365425A (en) * 1993-04-22 1994-11-15 The United States Of America As Represented By The Secretary Of The Air Force Method and system for measuring management effectiveness
WO1995000914A1 (en) * 1993-06-28 1995-01-05 Scott & White Memorial Hospital And Scott, Sherwood And Brindley Foundation Electronic medical record using text database
US5935060A (en) * 1996-07-12 1999-08-10 First Opinion Corporation Computerized medical diagnostic and treatment advice system including list based processing
US5652842A (en) 1994-03-01 1997-07-29 Healthshare Technology, Inc. Analysis and reporting of performance of service providers
US5738102A (en) * 1994-03-31 1998-04-14 Lemelson; Jerome H. Patient monitoring system
US5486999A (en) 1994-04-20 1996-01-23 Mebane; Andrew H. Apparatus and method for categorizing health care utilization
US5832447A (en) 1994-05-24 1998-11-03 Envoy Corporation Automated system and method for providing real-time verification of health insurance eligibility
US5557514A (en) * 1994-06-23 1996-09-17 Medicode, Inc. Method and system for generating statistically-based medical provider utilization profiles
US5845253A (en) * 1994-08-24 1998-12-01 Rensimer Enterprises, Ltd. System and method for recording patient-history data about on-going physician care procedures
US5737539A (en) * 1994-10-28 1998-04-07 Advanced Health Med-E-Systems Corp. Prescription creation system
US5657255C1 (en) * 1995-04-14 2002-06-11 Interleukin Genetics Inc Hierarchic biological modelling system and method
US5619991A (en) * 1995-04-26 1997-04-15 Lucent Technologies Inc. Delivery of medical services using electronic data communications
US5706441A (en) 1995-06-07 1998-01-06 Cigna Health Corporation Method and apparatus for objectively monitoring and assessing the performance of health-care providers
US5664109A (en) * 1995-06-07 1997-09-02 E-Systems, Inc. Method for extracting pre-defined data items from medical service records generated by health care providers
US5835897C1 (en) * 1995-06-22 2002-02-19 Symmetry Health Data Systems Computer-implemented method for profiling medical claims
US5899998A (en) * 1995-08-31 1999-05-04 Medcard Systems, Inc. Method and system for maintaining and updating computerized medical records
US5924073A (en) 1995-11-14 1999-07-13 Beacon Patient Physician Association, Llc System and method for assessing physician performance using robust multivariate techniques of statistical analysis
US5724573A (en) * 1995-12-22 1998-03-03 International Business Machines Corporation Method and system for mining quantitative association rules in large relational tables
US6125194A (en) 1996-02-06 2000-09-26 Caelum Research Corporation Method and system for re-screening nodules in radiological images using multi-resolution processing, neural network, and image processing
US6076088A (en) * 1996-02-09 2000-06-13 Paik; Woojin Information extraction system and method using concept relation concept (CRC) triples
US6678669B2 (en) * 1996-02-09 2004-01-13 Adeza Biomedical Corporation Method for selecting medical and biochemical diagnostic tests using neural network-related applications
US5811437A (en) 1996-05-21 1998-09-22 Eli Lilly And Company Methods of increasing nitric oxide synthesis
US6108635A (en) * 1996-05-22 2000-08-22 Interleukin Genetics, Inc. Integrated disease information system
US6083693A (en) 1996-06-14 2000-07-04 Curagen Corporation Identification and comparison of protein-protein interactions that occur in populations
US5903889A (en) * 1997-06-09 1999-05-11 Telaric, Inc. System and method for translating, collecting and archiving patient records
US6253186B1 (en) * 1996-08-14 2001-06-26 Blue Cross Blue Shield Of South Carolina Method and apparatus for detecting fraud
CN100335501C (zh) * 1996-09-26 2007-09-05 中外制药株式会社 抗人副甲状腺激素相关蛋白的抗体
US5924074A (en) 1996-09-27 1999-07-13 Azron Incorporated Electronic medical records system
AU3930797A (en) * 1996-09-30 1998-04-02 Smithkline Beecham Corporation Disease management method and system
US6532437B1 (en) * 1996-10-23 2003-03-11 Cornell Research Foundation, Inc. Crystalline frap complex
US6039688A (en) 1996-11-01 2000-03-21 Salus Media Inc. Therapeutic behavior modification program, compliance monitoring and feedback system
US6212626B1 (en) * 1996-11-13 2001-04-03 Intel Corporation Computer processor having a checker
US6151581A (en) 1996-12-17 2000-11-21 Pulsegroup Inc. System for and method of collecting and populating a database with physician/patient data for processing to improve practice quality and healthcare delivery
AU5405798A (en) 1996-12-30 1998-07-31 Imd Soft Ltd. Medical information system
WO1998039720A1 (en) * 1997-03-03 1998-09-11 University Of Florida Method and system for interactive prescription and distribution of drugs in conducting medical studies
US6259890B1 (en) * 1997-03-27 2001-07-10 Educational Testing Service System and method for computer based test creation
US6078894A (en) * 1997-03-28 2000-06-20 Clawson; Jeffrey J. Method and system for evaluating the performance of emergency medical dispatchers
US5937387A (en) * 1997-04-04 1999-08-10 Real Age, Inc. System and method for developing and selecting a customized wellness plan
US5903899A (en) * 1997-04-23 1999-05-11 Sun Microsystems, Inc. System and method for assisting exact Garbage collection by segregating the contents of a stack into sub stacks
US6587829B1 (en) 1997-07-31 2003-07-01 Schering Corporation Method and apparatus for improving patient compliance with prescriptions
US5908383A (en) 1997-09-17 1999-06-01 Brynjestad; Ulf Knowledge-based expert interactive system for pain
US6139494A (en) * 1997-10-15 2000-10-31 Health Informatics Tools Method and apparatus for an integrated clinical tele-informatics system
US6212526B1 (en) * 1997-12-02 2001-04-03 Microsoft Corporation Method for apparatus for efficient mining of classification models from databases
JP4183311B2 (ja) 1997-12-22 2008-11-19 株式会社リコー 文書の注釈方法、注釈装置および記録媒体
US6230142B1 (en) 1997-12-24 2001-05-08 Homeopt, Llc Health care data manipulation and analysis system
EP0936566A3 (de) * 1998-02-11 2002-01-23 Siemens Aktiengesellschaft System zur Durchführung medizinischer Studien
CN1155199C (zh) 1998-02-23 2004-06-23 国际商业机器公司 万维网浏览器中顺序链接的热对象及连续流视频浏览方法
JP3251225B2 (ja) * 1998-02-26 2002-01-28 勲 長澤 病棟情報システム
US6063693A (en) * 1998-03-23 2000-05-16 Telefonaktiebolaget Lm Ericsson Planar trenches
US20040067547A1 (en) 1998-03-31 2004-04-08 Stuart Harbron Rapid method for detecting micro-organisms and evaluating antimicrobial activity
EP1068568A4 (en) * 1998-04-03 2004-10-27 Triangle Pharmaceuticals Inc SYSTEMS, METHODS, AND COMPUTER PROGRAM PRODUCTS TO GUIDE THE SELECTION OF THERAPEUTIC SCHEMES $ i ()
US7018392B2 (en) * 1998-04-08 2006-03-28 Arthrocare Corporation Hemostatic system for body cavities
US6173280B1 (en) * 1998-04-24 2001-01-09 Hitachi America, Ltd. Method and apparatus for generating weighted association rules
US7444308B2 (en) * 2001-06-15 2008-10-28 Health Discovery Corporation Data mining platform for bioinformatics and other knowledge discovery
DE19820276A1 (de) 1998-05-07 1999-11-18 Gerd Assmann Berechnung des globalen Herzinfarktrisikos mittels neuronaler Netze aus Risikofaktoren
US7353238B1 (en) * 1998-06-12 2008-04-01 Outcome Sciences, Inc. Apparatus and methods for determining and processing medical outcomes
US6212519B1 (en) * 1998-06-30 2001-04-03 Simulconsult, Inc. Systems and methods for quantifying qualitative medical expressions
US6338042B1 (en) * 1998-07-10 2002-01-08 Siemens Information And Communication Networks, Inc. Method and apparatus for integrating competency measures in compensation decisions
US6915254B1 (en) * 1998-07-30 2005-07-05 A-Life Medical, Inc. Automatically assigning medical codes using natural language processing
US6266645B1 (en) 1998-09-01 2001-07-24 Imetrikus, Inc. Risk adjustment tools for analyzing patient electronic discharge records
US6356879B2 (en) * 1998-10-09 2002-03-12 International Business Machines Corporation Content based method for product-peer filtering
US6067466A (en) 1998-11-18 2000-05-23 New England Medical Center Hospitals, Inc. Diagnostic tool using a predictive instrument
US6341265B1 (en) 1998-12-03 2002-01-22 P5 E.Health Services, Inc. Provider claim editing and settlement system
US6381576B1 (en) 1998-12-16 2002-04-30 Edward Howard Gilbert Method, apparatus, and data structure for capturing and representing diagnostic, treatment, costs, and outcomes information in a form suitable for effective analysis and health care guidance
US6272472B1 (en) * 1998-12-29 2001-08-07 Intel Corporation Dynamic linking of supplier web sites to reseller web sites
JP2002533169A (ja) * 1998-12-29 2002-10-08 オキュロジックス コーポレイション レオロジー的処置方法および関連するアフェレーシスシステム
WO2000042530A1 (en) * 1999-01-15 2000-07-20 Metaedge Corporation Method for visualizing information in a data warehousing environment
US6067486A (en) * 1999-02-01 2000-05-23 General Electric Company Method and system for planning repair of an aircraft engine
US6128620A (en) * 1999-02-02 2000-10-03 Lemed Inc Medical database for litigation
US20040158193A1 (en) 1999-02-10 2004-08-12 Baxter International Inc. Medical apparatus using selective graphical interface
AU2054000A (en) 1999-02-26 2000-09-14 Lipomed, Inc. Methods, systems, and computer program products for analyzing and presenting risk assessment results based on nmr lipoprotein analysis of blood
US7418399B2 (en) * 1999-03-10 2008-08-26 Illinois Institute Of Technology Methods and kits for managing diagnosis and therapeutics of bacterial infections
US6484144B2 (en) 1999-03-23 2002-11-19 Dental Medicine International L.L.C. Method and system for healthcare treatment planning and assessment
US6529876B1 (en) 1999-03-26 2003-03-04 Stephen H. Dart Electronic template medical records coding system
US6302844B1 (en) 1999-03-31 2001-10-16 Walker Digital, Llc Patient care delivery system
CA2336303A1 (en) * 1999-04-28 2000-11-02 Alean Kirnak Electronic medical record registry including data replication
AU5133700A (en) * 1999-05-17 2000-12-05 Pharmacon Global Enterprises, Llc Data processing system for patient outcome and risk benchmarking and healthcare data base management
WO2000075820A2 (en) * 1999-06-02 2000-12-14 Algorithmics International Corp. Risk management system, distributed framework and method
US6312378B1 (en) 1999-06-03 2001-11-06 Cardiac Intelligence Corporation System and method for automated collection and analysis of patient information retrieved from an implantable medical device for remote patient care
US6611825B1 (en) * 1999-06-09 2003-08-26 The Boeing Company Method and system for text mining using multidimensional subspaces
US7256708B2 (en) 1999-06-23 2007-08-14 Visicu, Inc. Telecommunications network for remote patient monitoring
US6804656B1 (en) * 1999-06-23 2004-10-12 Visicu, Inc. System and method for providing continuous, expert network critical care services from a remote location(s)
US20010051882A1 (en) * 1999-07-13 2001-12-13 Murphy Kevin M. Integrated care management system
US6961687B1 (en) 1999-08-03 2005-11-01 Lockheed Martin Corporation Internet based product data management (PDM) system
US6523019B1 (en) * 1999-09-21 2003-02-18 Choicemaker Technologies, Inc. Probabilistic record linkage model derived from training data
US6611846B1 (en) * 1999-10-30 2003-08-26 Medtamic Holdings Method and system for medical patient data analysis
US20020077756A1 (en) 1999-11-29 2002-06-20 Scott Arouh Neural-network-based identification, and application, of genomic information practically relevant to diverse biological and sociological problems, including drug dosage estimation
US20020026332A1 (en) * 1999-12-06 2002-02-28 Snowden Guy B. System and method for automated creation of patient controlled records
US6980958B1 (en) 2000-01-11 2005-12-27 Zycare, Inc. Apparatus and methods for monitoring and modifying anticoagulation therapy of remotely located patients
US6645959B1 (en) * 2000-01-26 2003-11-11 Warner-Lambert Company Method for treating postoperative ileus
AU2001233104A1 (en) 2000-01-28 2001-08-07 Acurian, Inc. Systems and methods for selecting and recruiting investigators and subjects for clinical studies
WO2001059687A1 (en) * 2000-02-09 2001-08-16 Patientpower.Com, Llc Method and system for managing patient medical records
US20020068857A1 (en) * 2000-02-14 2002-06-06 Iliff Edwin C. Automated diagnostic system and method including reuse of diagnostic objects
US6941271B1 (en) * 2000-02-15 2005-09-06 James W. Soong Method for accessing component fields of a patient record by applying access rules determined by the patient
US20020038227A1 (en) * 2000-02-25 2002-03-28 Fey Christopher T. Method for centralized health data management
US6801816B2 (en) * 2000-02-28 2004-10-05 International Flavors & Fragrances Inc. Customer controlled manufacturing process and user interface
AU2001241515A1 (en) * 2000-03-03 2001-09-17 Joerg Hohnloser Medical risk assessment system and method
US6988075B1 (en) * 2000-03-15 2006-01-17 Hacker L Leonard Patient-controlled medical information system and method
US20020133495A1 (en) * 2000-03-16 2002-09-19 Rienhoff Hugh Y. Database system and method
JP2003529832A (ja) 2000-03-23 2003-10-07 ザ ジョンズ ホプキンズ ユニバーシティ バイオ監視検出および警告の方法並びにシステム
US6322504B1 (en) * 2000-03-27 2001-11-27 R And T, Llc Computerized interactive method and system for determining a risk of developing a disease and the consequences of developing the disease
CA2403874A1 (en) * 2000-03-28 2001-12-06 Dana-Farber Cancer Institute, Inc. Molecular database for antibody characterization
US20010032195A1 (en) * 2000-03-30 2001-10-18 Graichen Catherine Mary System and method for identifying productivity improvements in a business organization
US7274810B2 (en) 2000-04-11 2007-09-25 Cornell Research Foundation, Inc. System and method for three-dimensional image rendering and analysis
JP2001297157A (ja) 2000-04-12 2001-10-26 Terumo Corp 医療情報通信装置及びその制御方法、記憶媒体
WO2001082135A1 (en) * 2000-04-21 2001-11-01 Science Applications International Corporation System and method of supply chain management
US7483838B1 (en) 2000-04-21 2009-01-27 James D. Marks System and method for recruitment of candidates for clinical trials while maintaining security
US20030036683A1 (en) * 2000-05-01 2003-02-20 Kehr Bruce A. Method, system and computer program product for internet-enabled, patient monitoring system
US7630908B1 (en) 2000-05-01 2009-12-08 John Amrien Wireless electronic prescription scanning and management system
US20020010597A1 (en) 2000-05-19 2002-01-24 Mayer Gregg L. Systems and methods for electronic health management
US20020038310A1 (en) * 2000-07-17 2002-03-28 Reitberg Donald P. Single-patient drug trials used with accumulated database: genomic markers
WO2002008941A1 (en) 2000-07-20 2002-01-31 Marchosky J Alexander Patient-controlled automated medical record, diagnosis, and treatment system and method
US6826536B1 (en) 2000-07-22 2004-11-30 Bert Forman Health care billing monitor system for detecting health care provider fraud
US6915266B1 (en) 2000-07-31 2005-07-05 Aysha Saeed Method and system for providing evaluation data from tracked, formatted administrative data of a service provider
US20020029155A1 (en) * 2000-08-04 2002-03-07 Frank Hetzel Registration and ordering system
CA2420400A1 (en) * 2000-08-24 2002-02-28 Veritas Medicine, Inc. Recruiting a patient into a clinical trial
US7685005B2 (en) * 2000-08-29 2010-03-23 Medtronic, Inc. Medical device systems implemented network scheme for remote patient management
AU2001286902A1 (en) * 2000-08-30 2002-03-13 Healtheheart, Inc. Patient analysis and risk reduction system and associated methods
US20020077853A1 (en) 2000-09-15 2002-06-20 Kevin Boru System for selecting clinical trials
US6602136B1 (en) * 2000-10-11 2003-08-05 Igt Gaming device with a bonus scheme involving movement along paths with path change conditions
US20020123905A1 (en) * 2000-12-13 2002-09-05 Joane Goodroe Clinical operational and gainsharing information management system
US6938206B2 (en) * 2001-01-19 2005-08-30 Transolutions, Inc. System and method for creating a clinical resume
US6551243B2 (en) * 2001-01-24 2003-04-22 Siemens Medical Solutions Health Services Corporation System and user interface for use in providing medical information and health care delivery support
US7346521B2 (en) 2001-03-05 2008-03-18 Ims Health Incorporated System and methods for generating physician profiles concerning prescription therapy practices
US20020138492A1 (en) 2001-03-07 2002-09-26 David Kil Data mining application with improved data mining algorithm selection
EP1246113A1 (en) 2001-03-09 2002-10-02 Pihl Limited Method & apparatus for delivering healthcare
US6879970B2 (en) * 2001-04-02 2005-04-12 Invivodata, Inc. Apparatus and method for prediction and management of subject compliance in clinical research
US7392199B2 (en) 2001-05-01 2008-06-24 Quest Diagnostics Investments Incorporated Diagnosing inapparent diseases from common clinical tests using Bayesian analysis
AU2002305577A1 (en) 2001-05-15 2002-11-25 Dominic A. Marasco System and method for managing interactions between healthcare providers and pharma companies
US20030208382A1 (en) 2001-07-05 2003-11-06 Westfall Mark D Electronic medical record system and method
US20030028401A1 (en) 2001-07-17 2003-02-06 Leon Kaufman Customizable lung report generator
US7130457B2 (en) * 2001-07-17 2006-10-31 Accuimage Diagnostics Corp. Systems and graphical user interface for analyzing body images
US7529685B2 (en) * 2001-08-28 2009-05-05 Md Datacor, Inc. System, method, and apparatus for storing, retrieving, and integrating clinical, diagnostic, genomic, and therapeutic data
US20030050794A1 (en) * 2001-09-07 2003-03-13 Marjorie Keck Hospital emergency department resource utilization and optimization system
US6802810B2 (en) * 2001-09-21 2004-10-12 Active Health Management Care engine
JP4578742B2 (ja) * 2001-09-27 2010-11-10 株式会社森精機製作所 干渉防止装置
DE10247459A1 (de) 2001-10-31 2003-07-03 Caterpillar Inc Verfahren und System zur Analyse von Gesundheitsinformationen
JP2005523490A (ja) * 2001-11-02 2005-08-04 シーメンス　メディカル　ソリューションズ　ユーエスエー　インコーポレイテッド コンプライアンス自動化のための患者データマイニング
AU2002363329A1 (en) * 2001-11-06 2003-05-19 Elizabeth Gray Pharmacogenomics-based system for clinical applications
US20040078216A1 (en) 2002-02-01 2004-04-22 Gregory Toto Clinical trial process improvement method and system
US20040167804A1 (en) 2002-04-30 2004-08-26 Simpson Thomas L.C. Medical data communication notification and messaging system and method
US7698157B2 (en) 2002-06-12 2010-04-13 Anvita, Inc. System and method for multi-dimensional physician-specific data mining for pharmaceutical sales and marketing
US7418119B2 (en) 2002-10-31 2008-08-26 Siemens Computer Aided Diagnosis Ltd. Display for computer-aided evaluation of medical images and for establishing clinical recommendation therefrom
EP1573624A4 (en) 2002-12-03 2008-01-02 Siemens Medical Solutions SYSTEMS AND METHOD FOR THE AUTOMATED EXTRACTION AND PROCESSING OF FEE INFORMATION IN PATIENT RECORD SETS
US7523042B2 (en) 2003-01-17 2009-04-21 Providence Medical Group, A Division Of Providence Health System - Oregon Process and system for enhancing medical patient care
US7290016B2 (en) 2003-05-27 2007-10-30 Frank Hugh Byers Method and apparatus for obtaining and storing medical history records
US20050256738A1 (en) 2004-05-11 2005-11-17 Petrimoulx Harold J Methods and systems for identifying health care professionals with a prescribed attribute
US20060020465A1 (en) 2004-07-26 2006-01-26 Cousineau Leo E Ontology based system for data capture and knowledge representation
US20060122864A1 (en) 2004-12-02 2006-06-08 Gottesman Janell M Patient management network
US20060136259A1 (en) * 2004-12-17 2006-06-22 General Electric Company Multi-dimensional analysis of medical data
US20080275731A1 (en) 2005-05-18 2008-11-06 Rao R Bharat Patient data mining improvements
US8775208B2 (en) 2006-10-06 2014-07-08 Cerner Innovation, Inc. Patient outcomes in context of documentation
US8560335B2 (en) 2006-10-06 2013-10-15 Cerner Innovation, Inc. Viewing clinical activity details within a selected time period
US8355924B2 (en) 2006-10-06 2013-01-15 Cerner Innovation, Inc. Patient activity coordinator
US8589185B2 (en) 2006-10-06 2013-11-19 Cerner Innovation, Inc. Acknowledgement of previous results for medication administration
US20090171163A1 (en) 2007-12-31 2009-07-02 Mates John W Modular medical devices
US8754855B2 (en) 2008-06-27 2014-06-17 Microsoft Corporation Virtual touchpad
FR2944279B1 (fr) 2009-04-09 2011-06-24 Rhodia Operations Procede de fabrication d'une solution de sels de diacides/diamine(s)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104919450A (zh) * 2012-12-10 2015-09-16 皇家飞利浦有限公司 用于令多站点性能测量匿名并且用于控制对匿名数据的动作以及重新识别的方法和系统
CN111433862A (zh) * 2017-11-02 2020-07-17 皇家飞利浦有限公司 临床决策支持
CN108986917A (zh) * 2018-06-14 2018-12-11 杭州认知网络科技有限公司 临床试验匹配方法、装置及终端设备
CN113674867A (zh) * 2021-07-27 2021-11-19 上海药慧信息技术有限公司 临床数据挖掘方法、装置、电子设备和存储介质

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