DE19575029I2 - 4-Hydroxy-1-ÄÄÄ6-(4-phenylbutoxy)-hexalÜ-aminoÜ-methylÜ-1,3-benzoldimenthanol und seine physiologisch annehmbaren Salze - Google Patents
4-Hydroxy-1-ÄÄÄ6-(4-phenylbutoxy)-hexalÜ-aminoÜ-methylÜ-1,3-benzoldimenthanol und seine physiologisch annehmbaren SalzeInfo
- Publication number
- DE19575029I2 DE19575029I2 DE1995175029 DE19575029C DE19575029I2 DE 19575029 I2 DE19575029 I2 DE 19575029I2 DE 1995175029 DE1995175029 DE 1995175029 DE 19575029 C DE19575029 C DE 19575029C DE 19575029 I2 DE19575029 I2 DE 19575029I2
- Authority
- DE
- Germany
- Prior art keywords
- äää6
- methylü
- hexalü
- benzenedimenthanol
- aminoü
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
- C07C43/1742—Unsaturated ethers containing halogen containing six-membered aromatic rings with halogen atoms bound to the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838310477A GB8310477D0 (en) | 1983-04-18 | 1983-04-18 | Chemical compounds |
GB838317087A GB8317087D0 (en) | 1983-06-23 | 1983-06-23 | Chemical compounds |
GB838329568A GB8329568D0 (en) | 1983-11-04 | 1983-11-04 | Chemical compounds |
GB848401889A GB8401889D0 (en) | 1984-01-25 | 1984-01-25 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DE19575029I2 true DE19575029I2 (de) | 2002-11-07 |
Family
ID=27449465
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3448338A Expired - Lifetime DE3448338C2 (de) | 1983-04-18 | 1984-04-18 | |
DE3448452A Expired - Lifetime DE3448452C2 (de) | 1983-04-18 | 1984-04-18 | Phenylalkoxyalkylaminderivate und ihre Verwendung |
DE19843414752 Granted DE3414752A1 (de) | 1983-04-18 | 1984-04-18 | Phenethanolamin-verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE1995175029 Active DE19575029I2 (de) | 1983-04-18 | 1984-04-18 | 4-Hydroxy-1-ÄÄÄ6-(4-phenylbutoxy)-hexalÜ-aminoÜ-methylÜ-1,3-benzoldimenthanol und seine physiologisch annehmbaren Salze |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3448338A Expired - Lifetime DE3448338C2 (de) | 1983-04-18 | 1984-04-18 | |
DE3448452A Expired - Lifetime DE3448452C2 (de) | 1983-04-18 | 1984-04-18 | Phenylalkoxyalkylaminderivate und ihre Verwendung |
DE19843414752 Granted DE3414752A1 (de) | 1983-04-18 | 1984-04-18 | Phenethanolamin-verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Country Status (37)
Country | Link |
---|---|
US (5) | US4992474A (de) |
JP (2) | JPS63264443A (de) |
KR (1) | KR920004186B1 (de) |
AR (3) | AR244199A1 (de) |
AT (1) | AT390611B (de) |
AU (1) | AU573212B2 (de) |
BE (1) | BE899448A (de) |
BG (1) | BG61490B2 (de) |
CA (2) | CA1335999C (de) |
CH (2) | CH661497A5 (de) |
CY (1) | CY1482A (de) |
CZ (1) | CZ285602B6 (de) |
DE (4) | DE3448338C2 (de) |
DK (2) | DK167493B1 (de) |
ES (2) | ES531722A0 (de) |
FI (1) | FI85011C (de) |
FR (1) | FR2545482B1 (de) |
GB (2) | GB2140800B (de) |
GR (1) | GR79925B (de) |
HK (1) | HK36889A (de) |
HU (1) | HU200160B (de) |
IE (1) | IE57237B1 (de) |
IL (1) | IL71569A (de) |
IT (1) | IT1199112B (de) |
KE (1) | KE3864A (de) |
LU (2) | LU85329A1 (de) |
MX (1) | MX9203226A (de) |
MY (1) | MY102087A (de) |
NL (2) | NL188406C (de) |
NO (2) | NO159016C (de) |
NZ (2) | NZ221999A (de) |
PH (1) | PH21574A (de) |
PT (1) | PT78443B (de) |
SE (1) | SE462594B (de) |
SG (1) | SG12289G (de) |
SK (1) | SK278120B6 (de) |
ZW (1) | ZW6584A1 (de) |
Families Citing this family (180)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZW6584A1 (en) * | 1983-04-18 | 1985-04-17 | Glaxo Group Ltd | Phenethanolamine derivatives |
DE3513885A1 (de) * | 1984-04-17 | 1985-10-17 | Glaxo Group Ltd., London | Phenethanolaminverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
US4943591A (en) * | 1984-10-17 | 1990-07-24 | Glaxo Group Limited | Dichloroaniline derivatives |
GB8525321D0 (en) * | 1985-10-15 | 1985-11-20 | Glaxo Group Ltd | Chemical compounds |
EP0220054A3 (de) * | 1985-10-16 | 1987-12-02 | Glaxo Group Limited | Ethanolaminderivate |
GB8525484D0 (en) * | 1985-10-16 | 1985-11-20 | Glaxo Group Ltd | Chemical compounds |
GB8525483D0 (en) * | 1985-10-16 | 1985-11-20 | Glaxo Group Ltd | Chemical compounds |
EP0223410A3 (de) * | 1985-10-16 | 1987-11-19 | Glaxo Group Limited | Ethanolaminderivate |
JPS63290852A (ja) * | 1987-02-10 | 1988-11-28 | グラクソ、グループ、リミテッド | 化合物 |
US4937268A (en) * | 1987-03-12 | 1990-06-26 | Glaxo Group Limited | Chemical compounds |
GB8718938D0 (en) * | 1987-08-11 | 1987-09-16 | Glaxo Group Ltd | Chemical compounds |
GB8718940D0 (en) * | 1987-08-11 | 1987-09-16 | Glaxo Group Ltd | Chemical compounds |
DK633588A (da) * | 1987-11-13 | 1989-05-14 | Glaxo Group Ltd | Aminderivater |
ZA889405B (en) * | 1987-12-18 | 1989-12-27 | Glaxo Group Ltd | Ethanolamine derivatives |
EP0322164B1 (de) * | 1987-12-18 | 1993-09-22 | Glaxo Group Limited | Ethanolaminderivate |
GB2230775A (en) * | 1989-04-24 | 1990-10-31 | Glaxo Group Ltd | Phenethanolamine compounds |
GB8909273D0 (en) * | 1989-04-24 | 1989-06-07 | Glaxo Group Ltd | Chemical compounds |
US5290815A (en) * | 1989-09-07 | 1994-03-01 | Glaxo Group Limited | Treatment of inflammation and allergy |
CA2024789C (en) * | 1989-09-07 | 2001-02-06 | Malcolm Johnson | Compounds for the treatment of inflammation and allergy |
US5208226A (en) * | 1989-09-08 | 1993-05-04 | Glaxo Group Limited | Medicaments |
IT1241997B (it) * | 1989-09-08 | 1994-02-02 | Glaxo Group Ltd | Composizione farmaceutica per il trattamento di disturbi respiratori e metodo per la sua applicazione. |
US5270305A (en) | 1989-09-08 | 1993-12-14 | Glaxo Group Limited | Medicaments |
IL95590A (en) * | 1989-09-08 | 1996-06-18 | Glaxo Group Ltd | Medicinal preparations containing Salmetrol and Pluticasone Propionate |
AU629989B2 (en) * | 1989-10-10 | 1992-10-15 | Glaxo Group Limited | Phenethanolamine derivatives |
SK280967B6 (sk) | 1990-03-02 | 2000-10-09 | Glaxo Group Limited | Inhalačný prístroj |
MY105368A (en) | 1990-03-02 | 1994-09-30 | Glaxo Group Ltd | Inhalation device. |
US6536427B2 (en) | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
US5919827A (en) * | 1990-07-11 | 1999-07-06 | Sepracor Inc. | Method for treating asthma using optically pure R(-) salmeterol |
GB9026005D0 (en) * | 1990-11-29 | 1991-01-16 | Glaxo Group Ltd | Drug material suitable for micronisation |
CN1056974C (zh) * | 1992-02-11 | 2000-10-04 | 格拉克索公司 | 适宜于微粒化的药物材料的制备方法 |
AU1229892A (en) * | 1992-02-11 | 1993-09-03 | Glaxo Group Limited | Benzenedimethanol derivative suitable for micronisation |
AP323A (en) * | 1992-05-08 | 1994-03-07 | Glaxo Group Ltd | Drug material suitable for micronisation. |
GB9215274D0 (en) * | 1992-07-17 | 1992-09-02 | Scras | Derivatives of(phenylethyl-beta-ol)amine |
ES2065269B1 (es) * | 1993-05-11 | 1995-10-01 | S A L V A T Lab Sa | 6-(4-(fenilbutoxi) hexilaminometil-4-hidroxi-a1,a3-bencenodimetanol. procedimiento para la obtencion del mismo y nuevos intermedios utilizados en su preparacion. |
ES2121621T3 (es) * | 1993-12-10 | 1998-12-01 | Novartis Ag | Derivados de acido n,n'-bis(2-hidroxibencil)etilendiamino-n,n'-diacetico como agentes quelantes. |
GB9507768D0 (en) | 1995-04-13 | 1995-05-31 | Glaxo Group Ltd | Method of apparatus |
PT820322E (pt) | 1995-04-14 | 2002-10-31 | Smithkline Beecham Corp | Inalador com dosimetro para propionato de fluticasona |
EP0820414B1 (de) | 1995-04-14 | 2004-02-04 | SmithKline Beecham Corporation | Vorrichtung zur dosierten inhalierung von beclomethason-diproprionat |
NZ306280A (en) | 1995-04-14 | 1999-07-29 | Glaxo Wellcome Inc | Metered dose inhaler for salmeterol |
BR9604976A (pt) * | 1995-04-14 | 1998-06-09 | Glaxo Wellcome Inc | Inalador de dose medida sistema inalador de dose medida e uso do mesmo |
WO1998024753A1 (fr) | 1996-12-02 | 1998-06-11 | Chisso Corporation | Derives de nitro-alcool actifs optiquement, derives d'amino-alcool actifs optiquement et leur procede de preparation |
US6254882B1 (en) | 1997-09-16 | 2001-07-03 | Sepracor Inc. | Methods and compositions for treating pulmonary disorders using optically pure (S)—salmeterol |
AU764923B2 (en) * | 1998-06-01 | 2003-09-04 | Anthony J. Verbiscar | Topical transdermal treatments |
ES2142771B1 (es) * | 1998-09-28 | 2001-01-01 | Vita Invest Sa | Nuevos derivados de la 6-(4-fenil-butoxi) hexilamina y procedimiento para la obtencion de salmeterol. |
PT1169019E (pt) | 1999-04-14 | 2003-07-31 | Glaxo Group Ltd | Formulacao farmaceutica em aerossol |
DK1212089T3 (da) * | 1999-08-21 | 2006-07-24 | Altana Pharma Ag | Synergistisk kombination af Roflumilast og Salmeterol |
GB0009609D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Therapeutic compositions |
GB0009613D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Pharmaceutical compositions |
GB0014546D0 (en) * | 2000-06-14 | 2000-08-09 | Glaxo Group Ltd | A novel process |
GB0015043D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
US6759398B2 (en) * | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
ES2523930T3 (es) * | 2000-08-05 | 2014-12-02 | Glaxo Group Limited | Éster s-fluorometílico del ácido 6-alfa,9-alfa-difluoro-17-alfa-[(2-furanilcarbonil)oxi]-11-beta-hidroxi-16-alfa-metil-3-oxo-androst-1,4-dien-17-carbotioico como agente antiinflamatorio |
US6750210B2 (en) | 2000-08-05 | 2004-06-15 | Smithkline Beecham Corporation | Formulation containing novel anti-inflammatory androstane derivative |
US6787532B2 (en) | 2000-08-05 | 2004-09-07 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivatives |
US6858596B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
US6777400B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
GB0019172D0 (en) * | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
US6777399B2 (en) * | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6858593B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
WO2002024552A2 (en) | 2000-09-18 | 2002-03-28 | Glaxo Group Limited | Coated can for a metered dose inhaler |
GB0103630D0 (en) | 2001-02-14 | 2001-03-28 | Glaxo Group Ltd | Chemical compounds |
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- 1984-04-18 NO NO841568A patent/NO159016C/no not_active IP Right Cessation
- 1984-04-18 GB GB08410124A patent/GB2140800B/en not_active Expired
- 1984-04-18 CH CH4750/86A patent/CH667084A5/fr not_active IP Right Cessation
- 1984-04-18 IT IT48064/84A patent/IT1199112B/it active Protection Beyond IP Right Term
- 1984-04-18 DE DE1995175029 patent/DE19575029I2/de active Active
- 1984-04-18 KR KR1019840002030A patent/KR920004186B1/ko not_active IP Right Cessation
-
1985
- 1985-01-16 ES ES539625A patent/ES8609209A1/es not_active Expired
-
1986
- 1986-05-21 GB GB08612357A patent/GB2176476B/en not_active Expired
-
1987
- 1987-02-25 AR AR87306841A patent/AR245687A1/es active
- 1987-09-29 MY MYPI87002277A patent/MY102087A/en unknown
-
1988
- 1988-02-25 JP JP63043277A patent/JPS63264443A/ja active Granted
-
1989
- 1989-02-08 AR AR89313169A patent/AR247721A1/es active
- 1989-02-17 KE KE3864A patent/KE3864A/xx unknown
- 1989-02-24 SG SG122/89A patent/SG12289G/en unknown
- 1989-05-04 HK HK368/89A patent/HK36889A/xx not_active IP Right Cessation
- 1989-08-23 US US07/397,664 patent/US4992474A/en not_active Expired - Lifetime
- 1989-12-08 CY CY1482A patent/CY1482A/xx unknown
-
1990
- 1990-06-21 US US07/541,631 patent/US5091422A/en not_active Expired - Lifetime
- 1990-11-29 US US07/619,899 patent/US5126375A/en not_active Expired - Lifetime
-
1991
- 1991-12-19 US US07/810,183 patent/US5243076A/en not_active Expired - Lifetime
- 1991-12-23 SK SK4028-91A patent/SK278120B6/sk unknown
- 1991-12-23 CZ CS914028A patent/CZ285602B6/cs unknown
-
1992
- 1992-02-19 US US07/837,783 patent/US5225445A/en not_active Expired - Lifetime
- 1992-06-24 MX MX9203226A patent/MX9203226A/es unknown
- 1992-08-18 JP JP4219484A patent/JPH0729997B2/ja not_active Expired - Lifetime
- 1992-08-18 CA CA000616467A patent/CA1336004C/en not_active Expired - Lifetime
- 1992-12-30 DK DK199201580A patent/DK175083B1/da not_active IP Right Cessation
-
1993
- 1993-06-11 NL NL930066C patent/NL930066I2/nl unknown
- 1993-08-20 BG BG98059A patent/BG61490B2/bg unknown
-
1994
- 1994-09-22 NO NO1994017C patent/NO1994017I1/no unknown
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