DE19605260A1 - Modulares Heimdialysesystem - Google Patents
Modulares HeimdialysesystemInfo
- Publication number
- DE19605260A1 DE19605260A1 DE19605260A DE19605260A DE19605260A1 DE 19605260 A1 DE19605260 A1 DE 19605260A1 DE 19605260 A DE19605260 A DE 19605260A DE 19605260 A DE19605260 A DE 19605260A DE 19605260 A1 DE19605260 A1 DE 19605260A1
- Authority
- DE
- Germany
- Prior art keywords
- dialysate
- water
- dialyzer
- container
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
- B01D65/10—Testing of membranes or membrane apparatus; Detecting or repairing leaks
- B01D65/102—Detection of leaks in membranes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
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- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
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- A61M1/1601—Control or regulation
- A61M1/1603—Regulation parameters
- A61M1/1605—Physical characteristics of the dialysate fluid
- A61M1/1607—Physical characteristics of the dialysate fluid before use, i.e. upstream of dialyser
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- A—HUMAN NECESSITIES
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- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
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- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
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- A61M1/1609—Physical characteristics of the dialysate fluid after use, i.e. downstream of dialyser
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- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1649—Constructional aspects thereof with pulsatile dialysis fluid flow
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- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
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- A61M1/168—Sterilisation or cleaning before or after use
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
- A61M39/16—Tube connectors; Tube couplings having provision for disinfection or sterilisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/04—Specific process operations in the feed stream; Feed pretreatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/04—Backflushing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/16—Use of chemical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/32—By heating or pyrolysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S210/00—Liquid purification or separation
- Y10S210/929—Hemoultrafiltrate volume measurement or control processes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S215/00—Bottles and jars
- Y10S215/03—Medical
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
- Y10T137/7781—With separate connected fluid reactor surface
- Y10T137/7793—With opening bias [e.g., pressure regulator]
- Y10T137/7794—With relief valve
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
- Y10T137/7781—With separate connected fluid reactor surface
- Y10T137/7793—With opening bias [e.g., pressure regulator]
- Y10T137/7796—Senses inlet pressure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
- Y10T137/7781—With separate connected fluid reactor surface
- Y10T137/7793—With opening bias [e.g., pressure regulator]
- Y10T137/7797—Bias variable during operation
- Y10T137/7799—Liquid transfer
Description
Ein Teil umfaßt einen extrakorporalen Blutkreislauf und der andere einen Kreislauf oder einen Strömungsweg für das Dialysat. Typischerweise stellt der gesamte Kreislauf für das Blut einen Wegwerfartikel dar und umfaßt: 1) eine arterielle und venöse Fistelnadel, 2) ein arterielles (Einström-) und venöses (Ausström-)Schlauchset, 3) ein Dialysegerät, 4) eine physiologische Vorbefüllungslösung (Salzlösung) mit Infusionsbesteck und 5) einen Gerinnungshemmer wie z. B. Heparin oder Natriumzitrat mit Infusionsbesteck. Über die arterielle Nadel wird dem Patienten über einen geeigneten Zugang Blut entnommen, das dann über die arteriellen Blutschläuche zum Dialysegerät geführt wird.
P = Lichtintensität der LED 530
KC = Lichtabschwächung der Küvette 536 und des Dialysats
KS = Abschwächungskoeffizient aufgrund von Blut im Dialysat
PEXT1, PEXT2 = externe, überlagernde Lichtquellen
KPD1, KPD2 = Empfindlichkeitskoeffizienten der Photodioden 538 bzw. 534
VOFF1, VOFF2 = elektronische Offsetkoeffizienten der Verstärker 546 bzw. 540
VPD1 = (P·KC·KS + PEXT1)KKD1 + VOFF1.
- - Angestrebtes KT/V pro Behandlung, mit K als Harnstoffclearance des Katalysators in ml pro Minute vollständig gereinigten Blutes, T als Behandlungszeit und V als Verteilungsvolumen (Harnstoff im Patienten), welches etwa 58% des Körpergewichts des Patienten in Kilogramm entspricht. Details der Korrelationsberechnungen zwischen Natrium und Harnstoff sind im US-Patent 5,110,477 von Howard et al. beschrieben, auf welches hiermit Bezug genommen wird;
- - minimale Behandlungszeit, unabhängig davon, ob die KT/V- Vorgabe in einer kürzeren Zeit erreicht wurde;
- - vorgegebene Blutflußrate, welche die maximalen arteriellen und venösen Drücke limitiert;
- - Vorgaben hinsichtlich Trockengewicht oder Wasserentnahme mit vorprogrammierten Grenzen in Bezug auf die maximale Rate, mit der Fluid entfernt werden kann (der Gewichtsverlust) wird dann dadurch berechnet, daß man das Trockengewicht von dem vorher gemessenen Gewicht abzieht und das zusätzlich infundierte Fluid beim Vorfüllen, Zurückspülen und anderen Gelegenheiten berücksichtigt; oder
- - zu entfernendes Fluid, wobei beispielsweise unter akuten Bedingungen die zu entfernende Menge benötigt werden kann, die anstelle des Patientengewichts auf den Infusionsvolumina basiert und, weil das System dann nicht in der Lage ist, die Menge des zu entnehmenden Fluids aus der Relation Gewicht minus Trockengewicht automatisch zu berechnen, der Operator die zu entnehmende Fluidmenge direkt angeben muß.
Claims (67)
Wasser auf eine Temperatur unterhalb des Siedepunktes erhitzt, bei der das Wasser eine hohe desinfizierende Wirkung besitzt, und dieses Wasser durch das Wasseraufbereitungsmodul, den extrakorporalen Kreislauf und den Dialysatkreislauf solange zirkulieren läßt, bis ein hoher Desinfektionsgrad der Maschine erreicht ist.
eine Desinfektionsleitung, um Desinfektionsfluide von der Quelle der Desinfektionsfluide in den extrakorporalen Kreislauf zu leiten;
einen Desinfektionsverteiler, der einen ersten Anschluß zur Aufnahme der arteriellen Leitung und einen zweiten Anschluß zur Aufnahme der venösen Leitung aufweist;
einen Rücklauf, der eine Fluidverbindung mit dem Desinfektionsverteiler herstellt und Desinfektionsfluide aus dem extrakorporalen Kreislauf mit sich führt;
wobei die in den Desinfektionsverteiler durch die Desinfektionsleitung eingebrachten Fluide durch die arterielle und venöse Blutleitung geführt und via Rücklauf aus dem extrakorporalen Kreislauf ausgeleitet werden.
ein temperaturgesteuertes Mischventil mit Heiß- und Kaltwassereinlaß und einem Auslaß, durch den Wasser einer bestimmten Temperatur ausströmt,
einer Wasserfiltereinheit, die sich in Fluidkommunikation mit dem Auslaß des Mischventils befindet, und
einer Fluidleitung, um warmes, gefiltertes Wasser von der Wasserfiltereinheit zu dem Wassereinlaß der Dialysemaschine zu führen.
ein mit dem Behälter kommunizierendes Gehäuse;
einen ersten Anschluß in dem Gehäuse, durch den eine erste Dialysatchemikalie aus dem Gefäß in das Gehäuse gelangt;
einen zweiten Anschluß in dem Gehäuse, durch den eine zweite Dialysatchemikalie von dem zweiten Chargengefäß in das Gehäuse gelangt;
einen dritten Anschluß in dem Gehäuse, der das dritte Gefäß aufnimmt, wobei in dem dritten Gefäß Dialysatchemikalien, Salze, Nahrungszusätze, Medikamente, Reinigungsmittel oder Desinfektionsmittel aufbewahrt sind.
mindestens ein Gefäß zur Aufbewahrung von Dialysatchemikalienchargen;
einen Dialysatherstellungsbehälter, der Wasser und eine bestimmte Menge Dialysatchemikalien zur Bildung einer Dialysatcharge aufnimmt, und
dem Behälter zugeordnete Mittel, um die Chemikalienchargen automatisch aus den Gefäßen in den Dialysatherstellungsbehälter einzuführen.
wenigstens eine Flasche, die Dialysatchemikalien enthält und an deren Außenseite ein abnehmbarer, maschinenlesbarer Indikator befestigt ist;
einen Chemikalienapplikator, der mit dem Behälter kommuniziert, wobei der Chemikalienapplikator einen zwischen oberen und unteren Positionen bewegbaren Dorn umfaßt;
Mittel zur Befestigung der Flasche auf dem Chemikalienapplikator; und
Mittel zum Entfernen des abnehmbaren Indikators von der Flasche.
einen maschinenlesbaren Indikator an dem Gefäß anbringt, wobei der Indikator kodierte Informationen über den Chemikalieninhalt des Gefäßes enthält,
das Gefäß so an dem Chemikalienapplikator befestigt, daß sich der maschinenlesbare Indikator in einer ablesbaren Position befindet,
den Indikator abliest und die Information über den Flascheninhalt dekodiert,
die dekodierte Information mit den gespeicherten Daten über die für den Patienten geeigneten Dialysatchemikalien vergleicht,
den Patienten alarmiert, falls das Gefäß ungeeignete Dialysatchemikalien enthält, so daß der Benutzer das Gefäß durch ein die richtigen Chemikalien enthaltendes Gefäß ersetzen kann, und
nach Anbringen des Gefäßes mit den richtigen Chemikalien am Chemikalienapplikator, die Chemikalien in den Behälter einführt.
man das neue Dialysat vom Boden des Behälters abzieht, altes Dialysat über den Behälterkopf bei einer zweiten Temperatur so in den Behälter zurückführt, daß dabei praktisch keine Turbulenz entsteht, wobei die zweite Temperatur wärmer ist als die erste Temperatur,
Dialysat in den Behälterkopf einführt, wobei das Dialysat eine Temperatur besitzt, die größer ist als die erste Temperatur vor dem Rücklauf des alten Dialysats in den Behälter, so daß ein Temperaturgradient des Dialysats im Behälter erzeugt wird,
wobei das wärmere eingeführte Dialysat einen ersten Bereich im oberen Abschnitt des Behälters bildet und das alte in den Behälter zurückgeführte Dialysat sich in diesem ersten Abschnitt mit dem eingeführten wärmeren Dialysat mischt,
wobei der Temperaturunterschied zwischen der ersten und zweiten Temperatur des Dialysats bewirkt, daß altes und neues Dialysat sich in im wesentlichen zwei diskreten Zonen befinden, wobei das alte Dialysat in einer ersten Zone über dem neuen Dialysat in einer zweiten Zone ist, wobei sich dazwischen eine Grenzschicht befindet, die im Laufe der Dialysebehandlung des Patienten absinkt.
ein Vorfüllfluid durch den extrakorporalen Kreislauf pumpt,
das Vorfüllfluid von dem extrakorporalen Kreislauf durch den Dialysator in den Dialysatkreislauf pumpt, und
Blut von dem Patienten durch den extrakorporalen Kreislauf zum Dialysator pumpt und das Blut zum Patienten zurückleitet, wobei darauf geachtet wird, daß kein Vorfüllfluid zum Patienten gepumpt wird.
im wesentlichen alle Fluide, die gegebenenfalls auf der Dialysatseite des Dialysatfilters vorhanden sind, entfernt,
Luft auf die Dialysatorseite des Dialysatfilters pumpt, um den Dialysatfilter unter Druck zu setzen, und
die Druckentwicklung am Dialysatfilter mißt, und, falls sich ein Druck entwickelt, den Druckabfall bestimmt, wobei Druckanstieg und Druckabfall ein Maß für die Unversehrtheit der Membran des Dialysatfilters darstellen.
im wesentlichen alle gegebenenfalls auf der Blutseite der Membran vorhandenen Fluide entfernt,
Luft auf die Blutseite der Membran zum Unterdrucksetzen des Dialysators pumpt,
den Druckanstieg im Dialysator mißt, und falls ein Druckanstieg stattgefunden hat, den Druckabfall bestimmt, wobei Druckanstieg und Druckabfall Hinweise auf die Unversehrtheit der Membran des Dialysators geben.
Natriumionen enthaltendes Dialysat durch die Dialysatseite des Dialysators zirkulieren läßt,
kontinuierlich Wasser durch die Blutseite des Dialysators zirkulieren läßt, wobei das Wasser die Blutseite des Dialysators nur einmal durchläuft,
anfangs die Leitfähigkeit des Dialysats mißt,
die Leitfähigkeit des Dialysats erneut mißt, nachdem das Dialysat durch den Dialysator geleitet wurde,
die Clearance der Natriumionen durch den Dialysator aufgrund der Leitfähigkeitsmessungen berechnet, wobei die Leitfähigkeit des Dialysats nach Durchlaufen des Dialysators im wesentlichen konstant wird, weil Dialysat und gereinigtes Wasser durch den Dialysator zirkuliert werden, wobei die Natrium-Clearance der Harnstoff-Clearance des Dialysators entspricht.
Fluide aus dem Dialysatkreislauf durch den Dialysator in den extrakorporalen Kreislauf rückspült,
zyklische Änderungen der Flußrate und -richtung des Fluids in den Blutschläuchen und im Dialysator bewirkt,
wobei das Rückspülen und zyklische Ändern der Flußrate und -richtung die Blutseite des Dialysators von Blutbestandteilen reinigt, und
Fluide mit den Blutbestandteilen aus dem extrakorporalen Kreislauf pumpt.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19655227A DE19655227B4 (de) | 1995-02-13 | 1996-02-13 | Clearancetest für einen Dialysator eines modularen Heimdialysesystems |
DE19655224A DE19655224B4 (de) | 1995-02-13 | 1996-02-13 | Dialysattrennung in einem modularen Heimdialysesystem |
DE19655223A DE19655223B4 (de) | 1995-02-13 | 1996-02-13 | Verteiler für Desinfektionsmittel in einem modularen Heimdialysesystem |
DE19655226A DE19655226B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum Vorfüllen des extrakorporalen Kreislaufs eines modularen Heimdialysesystems |
DE19655228A DE19655228B4 (de) | 1995-02-13 | 1996-02-13 | Vorrichtung zum Entfernen von Luftbläschen aus dem Blutkreislauf eines modularen Heimdialysesystems |
DE19655225A DE19655225B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum Betrieb eines modularen Heimdialysesystems |
DE19655230A DE19655230B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum automatischen Vorfüllen des Dialysators eines modularen Heimdialysesystems |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US388275 | 1995-02-13 | ||
US08/388,275 US5591344A (en) | 1995-02-13 | 1995-02-13 | Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE19605260A1 true DE19605260A1 (de) | 1996-11-28 |
DE19605260B4 DE19605260B4 (de) | 2008-04-03 |
Family
ID=23533428
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19655225A Expired - Fee Related DE19655225B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum Betrieb eines modularen Heimdialysesystems |
DE19655223A Expired - Fee Related DE19655223B4 (de) | 1995-02-13 | 1996-02-13 | Verteiler für Desinfektionsmittel in einem modularen Heimdialysesystem |
DE19655230A Expired - Fee Related DE19655230B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum automatischen Vorfüllen des Dialysators eines modularen Heimdialysesystems |
DE19655226A Revoked DE19655226B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum Vorfüllen des extrakorporalen Kreislaufs eines modularen Heimdialysesystems |
DE19605260A Expired - Fee Related DE19605260B4 (de) | 1995-02-13 | 1996-02-13 | Modulares Heimdialysesystem |
DE19655224A Expired - Fee Related DE19655224B4 (de) | 1995-02-13 | 1996-02-13 | Dialysattrennung in einem modularen Heimdialysesystem |
DE19655228A Expired - Fee Related DE19655228B4 (de) | 1995-02-13 | 1996-02-13 | Vorrichtung zum Entfernen von Luftbläschen aus dem Blutkreislauf eines modularen Heimdialysesystems |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19655225A Expired - Fee Related DE19655225B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum Betrieb eines modularen Heimdialysesystems |
DE19655223A Expired - Fee Related DE19655223B4 (de) | 1995-02-13 | 1996-02-13 | Verteiler für Desinfektionsmittel in einem modularen Heimdialysesystem |
DE19655230A Expired - Fee Related DE19655230B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum automatischen Vorfüllen des Dialysators eines modularen Heimdialysesystems |
DE19655226A Revoked DE19655226B4 (de) | 1995-02-13 | 1996-02-13 | Verfahren zum Vorfüllen des extrakorporalen Kreislaufs eines modularen Heimdialysesystems |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19655224A Expired - Fee Related DE19655224B4 (de) | 1995-02-13 | 1996-02-13 | Dialysattrennung in einem modularen Heimdialysesystem |
DE19655228A Expired - Fee Related DE19655228B4 (de) | 1995-02-13 | 1996-02-13 | Vorrichtung zum Entfernen von Luftbläschen aus dem Blutkreislauf eines modularen Heimdialysesystems |
Country Status (7)
Country | Link |
---|---|
US (20) | US5591344A (de) |
JP (10) | JP2002503115A (de) |
AU (2) | AU4977996A (de) |
CA (5) | CA2271598C (de) |
DE (7) | DE19655225B4 (de) |
GB (10) | GB2310614A (de) |
WO (1) | WO1996025214A1 (de) |
Cited By (27)
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EP0846470A1 (de) | 1996-12-09 | 1998-06-10 | Aksys, Ltd. | Justierung der Dialysatsleitfähigkeit in einem chargenweisen Dialysatsherstellungsverfahren |
DE19926901A1 (de) * | 1999-06-12 | 2001-01-25 | Uwe Hasenzahl | Globale integrierte thermische Ringdesinfektion G-I-T-R Desinfektion |
EP1119404A1 (de) † | 1998-07-31 | 2001-08-01 | Nephros, Inc. | Verfahren zur effizienten hämodialysefiltration |
DE10059966A1 (de) * | 2000-12-02 | 2002-06-20 | Mesys Gmbh | Kartuschenhalterung für ein Dialysegerät oder dergleichen |
DE10111104A1 (de) * | 2001-03-02 | 2002-10-02 | Manfred Voelker | Reinstwasser-Versorgungsanlage und Verfahren zur thermischen Desinfektion des Reinstwasser-Versorgungssystems von Dialysegeräten |
EP1279409A2 (de) | 2001-07-25 | 2003-01-29 | Fresenius Medical Care Deutschland GmbH | Verfahren und Vorrichtung sowie Konnektor und Konzentratbehältereinheit zur Zubereitung von Lösungen |
DE10323843A1 (de) * | 2003-05-23 | 2004-12-23 | Fresenius Medical Care Deutschland Gmbh | Blutbehandlungsgerät |
DE102007009269A1 (de) * | 2007-02-26 | 2008-08-28 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Befüllen und/oder Entleeren eines Dialysegerätes |
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DE102009024606A1 (de) * | 2009-06-10 | 2010-12-16 | Fresenius Medical Care Deutschland Gmbh | Verfahren zum Entfernen von Blut aus einem extrakorporalen Blutkreislauf, Behandlungsvorrichtung sowie Schlauchsystem |
DE102009026060A1 (de) * | 2009-06-29 | 2010-12-30 | Fresenius Medical Care Deutschland Gmbh | Verfahren zur Präparierung und Aufrüstung einer Hämodialysemaschine zur Durchführung einer Hämodialysebehandlung sowie Hämodialysemaschine |
EP2583702A1 (de) * | 2011-10-20 | 2013-04-24 | D_MED Consulting AG | Verfahren zum Beenden einer Hämodialyse |
WO2013075692A2 (de) * | 2011-11-22 | 2013-05-30 | Saier, Beatrice | Vorrichtung und verfahren zum schaltbaren verbinden |
DE102012002497A1 (de) * | 2012-02-10 | 2013-08-14 | Fresenius Medical Care Deutschland Gmbh | Verbinder mit einem Behälter zur Herstellung einer individuell angepassten Lösung für die Dialyse |
DE102012004673A1 (de) * | 2012-03-12 | 2013-09-12 | Fresenius Medical Care Deutschland Gmbh | Schlauchadapter zum Beeinflussen des Drucks innerhalb eines Schlauchabschnitts während einer medizinischen Behandlung |
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DE102012104931A1 (de) * | 2012-06-06 | 2013-12-12 | B. Braun Avitum Ag | Verbinder und medizinisches Gerät zur extrakorporalen Blutbehandlung mit einem solchen Verbinder |
DE102013113641A1 (de) * | 2013-12-06 | 2015-06-11 | Winterhalter Gastronom Gmbh | Vorrichtung und Verfahren zur Wasseraufbereitung |
EP2324871B1 (de) | 2005-11-22 | 2016-06-22 | Nikkiso Co., Ltd. | Citrat-antikoagulationssystem für extrakorporale blutbehandlungen |
US9592332B2 (en) | 2009-04-23 | 2017-03-14 | Fresenius Medical Care Deutschland Gmbh | Method of removing blood from an extracorporeal blood circuit, treatment apparatus, and tube system |
DE102017001484A1 (de) | 2017-02-16 | 2018-08-16 | Fresenius Medical Care Deutschland Gmbh | Verfahren und Anordnung zum Kalibrieren von Vorrichtungen zur Erkennung von Blut oder Blutbestandteilen in einer Flüssigkeit |
US10071194B2 (en) | 2012-04-20 | 2018-09-11 | B. Braun Avitum Ag | Device for extra-corporal blood treatment with leakage sensor |
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JPH07236818A (ja) * | 1994-02-25 | 1995-09-12 | Dick Deguremon Kk | 内圧式中空糸モジュールの逆洗方法 |
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- 1995-11-17 US US08/560,335 patent/US5670050A/en not_active Expired - Lifetime
- 1995-11-17 US US08/560,305 patent/US5690821A/en not_active Expired - Lifetime
- 1995-11-17 US US08/560,017 patent/US5630935A/en not_active Expired - Lifetime
- 1995-11-17 US US08/559,124 patent/US5690831A/en not_active Expired - Lifetime
- 1995-11-17 US US08/559,148 patent/US5658456A/en not_active Expired - Lifetime
- 1995-11-17 US US08/560,439 patent/US5702606A/en not_active Expired - Lifetime
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1996
- 1996-01-02 US US08/582,137 patent/US5651893A/en not_active Expired - Lifetime
- 1996-02-01 CA CA002271598A patent/CA2271598C/en not_active Expired - Fee Related
- 1996-02-01 CA CA002271586A patent/CA2271586C/en not_active Expired - Fee Related
- 1996-02-01 CA CA002271583A patent/CA2271583C/en not_active Expired - Fee Related
- 1996-02-01 CA CA002168629A patent/CA2168629C/en not_active Expired - Fee Related
- 1996-02-01 CA CA002271595A patent/CA2271595C/en not_active Expired - Fee Related
- 1996-02-05 US US08/559,933 patent/US5674397A/en not_active Expired - Lifetime
- 1996-02-09 WO PCT/US1996/001885 patent/WO1996025214A1/en active Application Filing
- 1996-02-09 AU AU49779/96A patent/AU4977996A/en not_active Abandoned
- 1996-02-09 JP JP52506696A patent/JP2002503115A/ja active Pending
- 1996-02-09 AU AU44449/96A patent/AU698545B2/en not_active Ceased
- 1996-02-13 DE DE19655225A patent/DE19655225B4/de not_active Expired - Fee Related
- 1996-02-13 JP JP8025705A patent/JPH09618A/ja active Pending
- 1996-02-13 GB GB9705390A patent/GB2310614A/en not_active Withdrawn
- 1996-02-13 GB GB9706342A patent/GB2310616B/en not_active Expired - Fee Related
- 1996-02-13 GB GB9706343A patent/GB2310617B/en not_active Expired - Fee Related
- 1996-02-13 GB GB9705393A patent/GB2310615B/en not_active Expired - Fee Related
- 1996-02-13 DE DE19655223A patent/DE19655223B4/de not_active Expired - Fee Related
- 1996-02-13 DE DE19655230A patent/DE19655230B4/de not_active Expired - Fee Related
- 1996-02-13 GB GB9602941A patent/GB2299026B/en not_active Expired - Fee Related
- 1996-02-13 DE DE19655226A patent/DE19655226B4/de not_active Revoked
- 1996-02-13 GB GB9705372A patent/GB2310613B/en not_active Expired - Fee Related
- 1996-02-13 DE DE19605260A patent/DE19605260B4/de not_active Expired - Fee Related
- 1996-02-13 DE DE19655224A patent/DE19655224B4/de not_active Expired - Fee Related
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- 1996-02-13 GB GB9802830A patent/GB2320210B/en not_active Expired - Fee Related
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- 1996-02-13 DE DE19655228A patent/DE19655228B4/de not_active Expired - Fee Related
- 1996-03-01 US US08/560,502 patent/US5674390A/en not_active Expired - Lifetime
- 1996-03-01 US US08/560,334 patent/US5725776A/en not_active Expired - Lifetime
- 1996-03-14 US US08/559,834 patent/US5707086A/en not_active Expired - Lifetime
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1997
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2003
- 2003-02-06 JP JP2003029540A patent/JP3802495B2/ja not_active Expired - Lifetime
- 2003-02-06 JP JP2003029320A patent/JP3834552B2/ja not_active Expired - Fee Related
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Cited By (47)
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EP0846470A1 (de) | 1996-12-09 | 1998-06-10 | Aksys, Ltd. | Justierung der Dialysatsleitfähigkeit in einem chargenweisen Dialysatsherstellungsverfahren |
EP1119404B2 (de) † | 1998-07-31 | 2013-05-01 | Nephros, Inc. | Vorrichtung zur effizienten hämodiafiltration |
EP1119404A1 (de) † | 1998-07-31 | 2001-08-01 | Nephros, Inc. | Verfahren zur effizienten hämodialysefiltration |
DE19926901A1 (de) * | 1999-06-12 | 2001-01-25 | Uwe Hasenzahl | Globale integrierte thermische Ringdesinfektion G-I-T-R Desinfektion |
DE19931077B4 (de) * | 1999-07-06 | 2009-02-26 | Sterisafe Gmbh | Verfahrung zur Herstellung von Saurem Dialysekonzentrat |
DE10059966A1 (de) * | 2000-12-02 | 2002-06-20 | Mesys Gmbh | Kartuschenhalterung für ein Dialysegerät oder dergleichen |
DE10111104B4 (de) * | 2001-03-02 | 2004-08-26 | Manfred Völker | Reinstwasser-Versorgungsanlage und Verfahren zur thermischen Desinfektion des Reinstwasser-Versorgungssystems von Dialysegeräten |
DE10111104A1 (de) * | 2001-03-02 | 2002-10-02 | Manfred Voelker | Reinstwasser-Versorgungsanlage und Verfahren zur thermischen Desinfektion des Reinstwasser-Versorgungssystems von Dialysegeräten |
EP1279409A3 (de) * | 2001-07-25 | 2003-07-23 | Fresenius Medical Care Deutschland GmbH | Verfahren und Vorrichtung sowie Konnektor und Konzentratbehältereinheit zur Zubereitung von Lösungen |
DE10136262A1 (de) * | 2001-07-25 | 2003-02-20 | Fresenius Medical Care De Gmbh | Verfahren und Vorrichtung sowie Konnektor und Konzentratbehältereinheit zur Zubereitung von Lösungen |
US6814869B2 (en) | 2001-07-25 | 2004-11-09 | Fresenius Medical Care Deutschland Gmbh | Method and an apparatus as well as a connector and a concentrate container unit for the preparation of solutions |
EP1279409A2 (de) | 2001-07-25 | 2003-01-29 | Fresenius Medical Care Deutschland GmbH | Verfahren und Vorrichtung sowie Konnektor und Konzentratbehältereinheit zur Zubereitung von Lösungen |
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EP2324871B1 (de) | 2005-11-22 | 2016-06-22 | Nikkiso Co., Ltd. | Citrat-antikoagulationssystem für extrakorporale blutbehandlungen |
DE102007009269A1 (de) * | 2007-02-26 | 2008-08-28 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Befüllen und/oder Entleeren eines Dialysegerätes |
US8671996B2 (en) | 2007-02-26 | 2014-03-18 | Fresenius Medical Care Deutschland Gmbh | Method and device for filling and/or emptying a dialysis machine |
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US8394046B2 (en) | 2007-05-25 | 2013-03-12 | Fresenius Medical Care Deutschland Gmbh | Method and device for checking the correct coupling of a supply device to a therapy device |
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DE102009031043B4 (de) | 2009-06-30 | 2022-09-15 | Vivonic Gmbh | Versorgungssystem für wenigstens einen Reinstwasserverbraucher, insbesondere Dialysegerät |
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EP3376080A1 (de) * | 2011-11-22 | 2018-09-19 | Saier, Beatrice | Vorrichtung und verfahren zum schaltbaren verbinden |
WO2013075692A3 (de) * | 2011-11-22 | 2013-10-17 | Saier, Beatrice | Vorrichtung und verfahren zum schaltbaren verbinden |
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