DE29724585U1 - Flicken und Kit zur Wiederherstellung von Knorpel - Google Patents

Flicken und Kit zur Wiederherstellung von Knorpel

Info

Publication number
DE29724585U1
DE29724585U1 DE29724585U DE29724585U DE29724585U1 DE 29724585 U1 DE29724585 U1 DE 29724585U1 DE 29724585 U DE29724585 U DE 29724585U DE 29724585 U DE29724585 U DE 29724585U DE 29724585 U1 DE29724585 U1 DE 29724585U1
Authority
DE
Germany
Prior art keywords
patch
membrane
kit
cartilage
cover
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE29724585U
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Verigen AG
Original Assignee
VTS Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107401&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE29724585(U1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/704,891 external-priority patent/US5759190A/en
Application filed by VTS Holdings Ltd filed Critical VTS Holdings Ltd
Publication of DE29724585U1 publication Critical patent/DE29724585U1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2846—Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/38—Joints for elbows or knees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
    • A61F2002/30016—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A61F2002/30761—Support means for artificial cartilage, e.g. cartilage defect covering membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A61F2002/30762—Means for culturing cartilage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0019—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Description

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Claims (37)

1. Flicken zur Wiederherstellung von Knorpel, umfassend eine zellfreie resorbierbare Membran mit poröser Oberfläche sowie Chondrozytenzellen, die an der porösen Oberfläche der Membran anhaften, zur Verwendung sowohl als hämostatische Schranke als auch als Flicken zur Abdeckung eines Knorpeldefekts.
2. Flicken nach Anspruch 1, bei dem die Membran aus Collagen ist.
3. Flicken nach den Ansprüchen 1 und 2, bei dem die Membran eine Typ I und Typ III Collagenmembran ist.
4. Flicken nach den Ansprüchen 1 und 2, worin die Membran eine Typ II Collagenmembran ist.
5. Flicken nach einem der Ansprüche 1 bis 4, worin die Chondrozytenzellen autolog sind.
6. Flicken nach einem der Ansprüche 1 bis 4, worin die Chondrozytenzellen allogen sind.
7. Flicken nach einem der Ansprüche 1 bis 4, worin die Chondrozytenzellen xenogen sind.
8. Flicken nach einem der Ansprüche 1 bis 7, zusätzlich gekennzeichnet durch einen an die Membran angrenzenden biokompatiblen Klebstoff.
9. Flicken nach einem der Ansprüche 1 bis 8, bei dem die Membran derart ausgebildet ist, um einen Defekt des Gelenkknorpels zu bedecken.
10. Kit für die Chondrozytentransplantation auf die Oberfläche eines Gelenks, das eine defekten Knorpelbereich aufweist, wobei der Kit umfasst:
  • - eine hämostatische Schranke zur Hemmung der Gefäßneubildung und des Einbringens von Zellen in sich entwickelndes Knorpelgewebe,
  • - einen Abdeckflicken, der derart ausgebildet ist, um die Oberfläche und die hämostatische Schranke zu bedecken,
  • - Chondrozyten, die positioniert sind, um an dem Abdeckflicken zu haften, und
  • - einen organischen Klebstoff, der derart ausgebildet ist, um die hämostatische Schranke und/oder den Abdeckflicken an der Oberfläche zu befestigen.
11. Kit nach Anspruch 10, bei dem der Abdeckflicken und die hämostatische Schranke kombiniert sind, sodass der Kit umfasst:
- eine Kombination aus Abdeckflicken/hämostatische Schranke zum Bedecken des defekten Bereichs eines Knorpels,
  • - Chondrozyten, die vorgesehen sind, um an der Kombination Abdeckflickenlhämostatische Schranke zu haften, und
  • - einen organischen Klebstoff.
12. Kit nach Anspruch 10, bei dem der organische Klebstoff in Kombination mit dem Abdeckflicken als die hämostatische Schranke wirkt und sie dadurch ersetzt.
13. Kit nach den Ansprüchen 10 oder 11, bei dem die hämostatische Schranke, der Abdeckflicken und/oder die Kombination aus Abdeckflicken und hämostatischer Schranke aus einer resorbierbaren, zellfreien Membran mit einer porösen Oberfläche bestehen.
14. Kit nach Anspruch 12, umfassend:
  • - einen Abdeckflicken, der derart ausgebildet ist, um die Oberfläche zu bedecken,
  • - Chondrozyten, die so plaziert werden sollen, dass sie an den Abdeckflicken haften, und
  • - einen organischen Klebstoff, der derart ausgebildet ist, um die Oberfläche zu bedecken.
15. Kit nach Anspruch 14, bei dem der Abdeckflicken derart ausgebildet ist, um das Anhaften der Chondrozytenzellen an die poröse Oberfläche zu bewirken.
16. Kit nach einem der Ansprüche 12 bis 15, bei dem der Abdeckflicken aus einer resorbierbaren zellfreien Membran mit einer porösen Oberfläche besteht.
17. Kit nach einem der Ansprüche 13 bis 16, in dem die Membran aus Collagen ist.
18. Kit nach einem der Ansprüche 13 bis 16, bei dem die Membran eine Typ I und Typ III Collagenmembran ist.
19. Kit nach einem der Ansprüche 13 bis 17, bei dem die Membran eine Typ II Collagenmembran ist.
20. Kit nach einem der Ansprüche 10 bis 19, bei dem die Chondrozyten autolog sind.
21. Kit nach einem der Ansprüche 10 bis 19, bei dem die Chondrozyten allogen sind.
22. Kit nach einem der Ansprüche 10 bis 19, bei dem die Chondrozyten xenogen sind.
23. Flicken zur Wiederherstellung von Knorpel, umfassend eine resorbierbare zellfreie Membran, die eine poröse Oberfläche aufweist, sowie Chondrozytenzellen, die an die poröse Oberfläche der Membran haften, wobei der Flicken derart ausgebildet ist, um einen Knorpeldefekt zu bedecken.
24. Flicken nach Anspruch 23, bei dem die Membran aus Collagen ist.
25. Flicken nach den Ansprüchen 23 und 24, bei dem die Membran eine Typ I und Typ III Collagenmembran ist.
26. Flicken nach den Ansprüchen 23 und 24, bei dem die Membran eine Typ II Collagenmembran ist.
27. Flicken nach einem der Ansprüche 23 bis 26, bei dem die Chondrozytenzellen autolog sind.
28. Flicken nach einem der Ansprüche 23 bis 26, bei dem die Chondrozytenzellen allogen sind.
29. Flicken nach einem der Ansprüche 23 bis 29, bei dem die Chondrozytenzellen xenogen sind.
30. Flicken nach einem der Ansprüche 23 bis 28, der weiterhin angrenzend an die Membran einen biokompatiblen Klebstoff aufweist.
31. Flicken nach einem der Ansprüche 23 bis 30, bei dem die Membran derart ausgebildet ist, um einen Knorpelgelenkdefekt zu bedecken.
32. Flicken nach Anspruch 23, der weiterhin einen organischen Klebstoff zum Anhaften an den defekten Knorpelbereich aufweist.
33. Flicken nach Anspruch 32, bei dem die zellfreie Membran derart ausgebildet ist, um sowohl als ein Abdeckflicken als auch als eine hämostatische Schranke zu wirken.
34. Flicken nach Anspruch 23, bei dem die poröse Oberfläche derart ausgebildet ist, dass sie Chondrozytenzellen an einem Rand der porösen Oberfläche anhaften lässt.
35. Flicken zur Wiederherstellung von Knorpel, umfassend eine resorbierbare zellfreie Membran, die eine poröse Oberfläche aufweist, wobei der Flicken derart konfiguriert ist, dass er zum Bedecken des Bereichs eines Knorpelschadens geeignet ist.
36. Flicken nach Anspruch 35, der weiterhin derart konfiguriert ist, dass er es gestattet, Chondrozytenzellen an seiner porösen Oberfläche anzuhaften.
DE29724585U 1996-08-30 1997-08-29 Flicken und Kit zur Wiederherstellung von Knorpel Expired - Lifetime DE29724585U1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/704,891 US5759190A (en) 1996-08-30 1996-08-30 Method and kit for autologous transplantation
US08/857,090 US5989269A (en) 1996-08-30 1997-05-15 Method, instruments and kit for autologous transplantation
EP97939677A EP1006950B1 (de) 1996-08-30 1997-08-29 Nit zur chondrozytentransplantation in einem gelenk

Publications (1)

Publication Number Publication Date
DE29724585U1 true DE29724585U1 (de) 2002-05-16

Family

ID=27107401

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69739363T Expired - Lifetime DE69739363D1 (de) 1996-08-30 1997-08-29 Verfahren zur Herstellung eines Kits zur autologen Transplantation
DE29724585U Expired - Lifetime DE29724585U1 (de) 1996-08-30 1997-08-29 Flicken und Kit zur Wiederherstellung von Knorpel
DE69726896T Expired - Lifetime DE69726896T2 (de) 1996-08-30 1997-08-29 Trägerstruktur für die Chondrozytentransplantation zur Reparatur von Knorpeln und Gelenken
DE69728569T Expired - Lifetime DE69728569T2 (de) 1996-08-30 1997-08-29 Kit zur Chondrozytentransplantation in einem Gelenk

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Families Citing this family (205)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186673A1 (en) * 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US5940807A (en) * 1996-05-24 1999-08-17 Purcell; Daniel S. Automated and independently accessible inventory information exchange system
US20060025786A1 (en) * 1996-08-30 2006-02-02 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US5989269A (en) * 1996-08-30 1999-11-23 Vts Holdings L.L.C. Method, instruments and kit for autologous transplantation
US20020173806A1 (en) * 1996-08-30 2002-11-21 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US6569172B2 (en) * 1996-08-30 2003-05-27 Verigen Transplantation Service International (Vtsi) Method, instruments, and kit for autologous transplantation
US8735773B2 (en) 2007-02-14 2014-05-27 Conformis, Inc. Implant device and method for manufacture
US7618451B2 (en) 2001-05-25 2009-11-17 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
US8480754B2 (en) 2001-05-25 2013-07-09 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US8771365B2 (en) 2009-02-25 2014-07-08 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs, and related tools
US8556983B2 (en) 2001-05-25 2013-10-15 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US8545569B2 (en) 2001-05-25 2013-10-01 Conformis, Inc. Patient selectable knee arthroplasty devices
US7468075B2 (en) 2001-05-25 2008-12-23 Conformis, Inc. Methods and compositions for articular repair
US8882847B2 (en) 2001-05-25 2014-11-11 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US9603711B2 (en) 2001-05-25 2017-03-28 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US7799077B2 (en) * 2002-10-07 2010-09-21 Conformis, Inc. Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces
US8234097B2 (en) 2001-05-25 2012-07-31 Conformis, Inc. Automated systems for manufacturing patient-specific orthopedic implants and instrumentation
US7534263B2 (en) 2001-05-25 2009-05-19 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US8083745B2 (en) 2001-05-25 2011-12-27 Conformis, Inc. Surgical tools for arthroplasty
US8858981B2 (en) * 1997-10-10 2014-10-14 Ed. Geistlich Soehne Fuer Chemistrie Industrie Bone healing material comprising matrix carrying bone-forming cells
US20050186283A1 (en) * 1997-10-10 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US9034315B2 (en) * 1997-10-10 2015-05-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Cell-charged multi-layer collagen membrane
US20030180263A1 (en) * 2002-02-21 2003-09-25 Peter Geistlich Resorbable extracellular matrix for reconstruction of bone
US8563232B2 (en) 2000-09-12 2013-10-22 Lifenet Health Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
US20100030340A1 (en) * 1998-06-30 2010-02-04 Wolfinbarger Jr Lloyd Plasticized Grafts and Methods of Making and Using Same
US6293970B1 (en) 1998-06-30 2001-09-25 Lifenet Plasticized bone and soft tissue grafts and methods of making and using same
US20080077251A1 (en) * 1999-06-07 2008-03-27 Chen Silvia S Cleaning and devitalization of cartilage
EP1104313A2 (de) * 1998-08-14 2001-06-06 Verigen Transplantation Service International (VTSI) AG Instrumente und werkstoffe für knorpelzellen-transplantation
EP1656960A1 (de) * 1998-08-14 2006-05-17 Verigen AG Instrumente und Werkstoffe für Knorpelzellentransplantation
AU772012B2 (en) 1998-09-14 2004-04-08 Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and preventing damage
US7239908B1 (en) 1998-09-14 2007-07-03 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
US7184814B2 (en) 1998-09-14 2007-02-27 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and assessing cartilage loss
US20020081732A1 (en) 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
US7615373B2 (en) 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US7476250B1 (en) * 1999-04-06 2009-01-13 Mansmann Kevin A Semi-permeable membranes to assist in cartilage repair
US6179840B1 (en) 1999-07-23 2001-01-30 Ethicon, Inc. Graft fixation device and method
US20020095157A1 (en) 1999-07-23 2002-07-18 Bowman Steven M. Graft fixation device combination
EP1441028A3 (de) * 1999-07-28 2005-01-05 Interface Biotech A/S Zellkultivierungsverfahren zur Herstellung von Knorpelzellen/Knorpelbildungszellen
MXPA02001133A (es) * 1999-08-02 2003-04-10 Verigen Transplantation Serv Equipo para el trasplante de celulas condrocitos.
US20020116063A1 (en) * 1999-08-02 2002-08-22 Bruno Giannetti Kit for chondrocyte cell transplantation
DE60041670D1 (de) * 1999-12-03 2009-04-09 Univ Leeds Wiederherstellung von beschädigtem Gewebe
US6626945B2 (en) * 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US7678151B2 (en) 2000-05-01 2010-03-16 Ek Steven W System and method for joint resurface repair
US7163541B2 (en) 2002-12-03 2007-01-16 Arthrosurface Incorporated Tibial resurfacing system
JP2003531657A (ja) * 2000-05-01 2003-10-28 アースロサーフェス， インク． 関節面付け替え修復システム及び方法
EP2314257B9 (de) * 2000-05-01 2013-02-27 ArthroSurface, Inc. System zur Gelenkoberflächenerneuerung
US6610067B2 (en) 2000-05-01 2003-08-26 Arthrosurface, Incorporated System and method for joint resurface repair
US8177841B2 (en) 2000-05-01 2012-05-15 Arthrosurface Inc. System and method for joint resurface repair
US7713305B2 (en) * 2000-05-01 2010-05-11 Arthrosurface, Inc. Articular surface implant
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
EP1315756A2 (de) 2000-09-01 2003-06-04 Virginia Commonwealth University Intellectual Property Foundation Elektroplattierte fibrin-basierte träger und gewebe
WO2002022014A1 (en) 2000-09-14 2002-03-21 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
US6599323B2 (en) * 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use
US20020127265A1 (en) * 2000-12-21 2002-09-12 Bowman Steven M. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US6852330B2 (en) * 2000-12-21 2005-02-08 Depuy Mitek, Inc. Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
CA2365376C (en) * 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US20040151705A1 (en) 2002-03-22 2004-08-05 Shuichi Mizuno Neo-cartilage constructs and a method for preparation thereof
AU784394B2 (en) 2001-04-27 2006-03-23 Geistlich Pharma Ag Method and membrane for mucosa regeneration
US8951260B2 (en) 2001-05-25 2015-02-10 Conformis, Inc. Surgical cutting guide
US8439926B2 (en) 2001-05-25 2013-05-14 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
CA2447694A1 (en) 2001-05-25 2002-12-05 Imaging Therapeutics, Inc. Methods and compositions for articular resurfacing
US6482209B1 (en) 2001-06-14 2002-11-19 Gerard A. Engh Apparatus and method for sculpting the surface of a joint
US6723102B2 (en) * 2001-06-14 2004-04-20 Alexandria Research Technologies, Llc Apparatus and method for minimally invasive total joint replacement
US7819918B2 (en) 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
JP2005515802A (ja) 2001-07-16 2005-06-02 デピュイ・プロダクツ・インコーポレイテッド 混成生物／合成品型多孔質細胞外基質支持骨格
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
EP1416888A4 (de) 2001-07-16 2007-04-25 Depuy Products Inc Vorrichtung und verfahren zur regeneration des meniskus
US7361195B2 (en) 2001-07-16 2008-04-22 Depuy Products, Inc. Cartilage repair apparatus and method
US20050027307A1 (en) * 2001-07-16 2005-02-03 Schwartz Herbert Eugene Unitary surgical device and method
US20030033021A1 (en) 2001-07-16 2003-02-13 Plouhar Pamela Lynn Cartilage repair and regeneration scaffold and method
US7201917B2 (en) 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
JP4197158B2 (ja) 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 天然に発生する生物学的に誘導されている材料による装置
WO2003026689A1 (en) * 2001-09-24 2003-04-03 Verigen Ag Autologous growth factor cocktail composition, method of production and use
AU2002330168B2 (en) * 2001-10-01 2006-11-09 Covidien Lp Apparatus and method for the repair of articular cartilage defects
CA2412012C (en) * 2001-11-20 2011-08-02 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage
BR0307033A (pt) * 2002-01-22 2004-12-07 Pfizer ácidos 3-(imidazolil)-2-aminopropanóicos para o uso como inibidores tafi-a para o tratamento de doenças trombóticas
US7537780B2 (en) * 2002-03-22 2009-05-26 Histogenics Corporation Method for preparing and implanting a cartilage construct to treat cartilage lesions
WO2003092542A2 (en) * 2002-05-01 2003-11-13 Verigen Ag Injectable chondrocyte implant
SE0201479D0 (sv) * 2002-05-16 2002-05-16 Pharmacia Groningen Bv Kit and method in eye surgery
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
US20040136968A1 (en) * 2002-09-27 2004-07-15 Verigen Ag Autologous cells on a support matrix for tissue repair
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7824701B2 (en) 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
AU2003287190A1 (en) 2002-10-23 2004-05-13 Alastair J. T. Clemow Modular femoral component for a total knee joint replacement for minimally invasive implantation
AU2003290757A1 (en) 2002-11-07 2004-06-03 Conformis, Inc. Methods for determing meniscal size and shape and for devising treatment
US20060147332A1 (en) 2004-12-30 2006-07-06 Howmedica Osteonics Corp. Laser-produced porous structure
US7537664B2 (en) 2002-11-08 2009-05-26 Howmedica Osteonics Corp. Laser-produced porous surface
US7901408B2 (en) 2002-12-03 2011-03-08 Arthrosurface, Inc. System and method for retrograde procedure
AU2003900620A0 (en) * 2003-02-12 2003-02-27 Australian Surgical Design And Manufacture Pty Limited Arthroscopic chondrocyte implantation method and device
US8388624B2 (en) 2003-02-24 2013-03-05 Arthrosurface Incorporated Trochlear resurfacing system and method
US8197837B2 (en) 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US7067123B2 (en) * 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US20050064042A1 (en) * 2003-04-29 2005-03-24 Musculoskeletal Transplant Foundation Cartilage implant plug with fibrin glue and method for implantation
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
AU2004246749A1 (en) * 2003-06-12 2004-12-23 Interface Biotech A/S A method for cell implantation
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
US20050046915A1 (en) * 2003-08-22 2005-03-03 Fuji Photo Film Co., Ltd. Hologram recording material composition, hologram recording material and hologram recording method
DE10349722A1 (de) 2003-10-23 2005-06-16 Beschorner, Katharina, Dr. Zusammensetzung zur Arthrose-/Arthritisbehandlung, insbesondere von Gelenken
GB0325141D0 (en) * 2003-10-28 2003-12-03 Xiros Plc Repair of damaged tissue on a bone site
AU2006203909A1 (en) 2003-11-20 2006-07-13 Arthrosurface, Inc. System and method for retrograde procedure
CA2546582A1 (en) 2003-11-20 2005-06-09 Arthrosurface, Inc. Retrograde delivery of resurfacing devices
US7951163B2 (en) 2003-11-20 2011-05-31 Arthrosurface, Inc. Retrograde excision system and apparatus
US7316822B2 (en) 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
US7901461B2 (en) 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
ES2403357T3 (es) 2003-12-11 2013-05-17 Isto Technologies Inc. Sistema de cartílago particulado
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
EP1576957A1 (de) * 2004-03-18 2005-09-21 Universiteit Twente Wiederherstellung zerstörten Gewebes mit Hilfe von pluripotenten Zellen
US8221780B2 (en) 2004-04-20 2012-07-17 Depuy Mitek, Inc. Nonwoven tissue scaffold
US8657881B2 (en) 2004-04-20 2014-02-25 Depuy Mitek, Llc Meniscal repair scaffold
US8137686B2 (en) 2004-04-20 2012-03-20 Depuy Mitek, Inc. Nonwoven tissue scaffold
US7569233B2 (en) * 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
CA2470463C (en) * 2004-06-09 2012-09-18 Lornamead Brands, Inc. Tooth whitening products and methods of making the same
WO2006004885A2 (en) 2004-06-28 2006-01-12 Arthrosurface, Inc. System for articular surface replacement
WO2006022671A1 (en) * 2004-07-30 2006-03-02 Histogenics Corporation Method for in situ repair of injured, damaged, diseased or aged articular cartilage using neo-cartilage constructs and a method for preparation thereof
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20060111778A1 (en) * 2004-10-29 2006-05-25 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
US7513866B2 (en) 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7828853B2 (en) 2004-11-22 2010-11-09 Arthrosurface, Inc. Articular surface implant and delivery system
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
CN100384390C (zh) * 2005-01-13 2008-04-30 中国人民解放军第三军医大学第一附属医院 组织工程骨与软骨复合组织及其体外构建方法
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
EP1916964A4 (de) 2005-08-26 2015-11-04 Zimmer Inc Implantate und verfahren zur behebung, ersetzung und behandlung von gelenkkrankheiten
KR20080065606A (ko) * 2005-09-02 2008-07-14 인터페이스 바이오텍 에이/에스 세포 이식 방법
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
CA2623834A1 (en) 2005-09-30 2007-04-12 Conformis, Inc. Joint arthroplasty devices
EP1951158A4 (de) 2005-11-21 2010-03-31 Vertegen Inc Vorrichtungen und verfahren zur behandlung von facettengelenken, uncovertebralgelenken, costovertebralgelenken und anderen gelenken
US8728387B2 (en) 2005-12-06 2014-05-20 Howmedica Osteonics Corp. Laser-produced porous surface
EP1803513B1 (de) * 2005-12-30 2017-03-29 Howmedica Osteonics Corp. Herstellungsverfahren von Implantaten mittels Laser
TWI584796B (zh) 2006-02-06 2017-06-01 康福美斯公司 患者可選擇式關節置換術裝置及外科工具
US8623026B2 (en) 2006-02-06 2014-01-07 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief
US20070288021A1 (en) * 2006-06-07 2007-12-13 Howmedica Osteonics Corp. Flexible joint implant
US8147861B2 (en) * 2006-08-15 2012-04-03 Howmedica Osteonics Corp. Antimicrobial implant
EP2061429A2 (de) * 2006-09-07 2009-05-27 Ed. Geistlich Söhne Ag Für Chemische Industrie Verfahren zur behandlung von knochenkrebs
KR20080037883A (ko) * 2006-10-27 2008-05-02 세원셀론텍(주) 메디컬 키트 및 이의 사용방법
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US9358029B2 (en) 2006-12-11 2016-06-07 Arthrosurface Incorporated Retrograde resection apparatus and method
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
EP2591756A1 (de) 2007-02-14 2013-05-15 Conformis, Inc. Implantat und Herstellungsverfahren
US7758643B2 (en) * 2007-02-26 2010-07-20 Biomet Sports Medicine, Llc Stable cartilage defect repair plug
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20090012629A1 (en) 2007-04-12 2009-01-08 Isto Technologies, Inc. Compositions and methods for tissue repair
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
US9125743B2 (en) * 2007-07-16 2015-09-08 Lifenet Health Devitalization and recellularization of cartilage
US9744043B2 (en) * 2007-07-16 2017-08-29 Lifenet Health Crafting of cartilage
WO2009014718A1 (en) 2007-07-24 2009-01-29 Porex Corporation Porous laser sintered articles
WO2009026392A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation A method for improvement of differentiation of mesenchymal stem cells using a double-structured tissue implant
WO2009051701A2 (en) * 2007-10-15 2009-04-23 Wake Forest University Health Sciences Methods and compositions for printing biologically compatible nanotube composites of autologous tissue
US20110014267A1 (en) * 2008-02-29 2011-01-20 Hanne Everland Biosynthetic cartilaginous matrix and methods for their production
CN102123745A (zh) * 2008-02-29 2011-07-13 科洛普拉斯特公司 用于受试者中活组织的增加和再生的组合物和方法
WO2009111481A1 (en) 2008-03-03 2009-09-11 Arthrosurface Incorporated Bone resurfacing system and method
WO2009111626A2 (en) 2008-03-05 2009-09-11 Conformis, Inc. Implants for altering wear patterns of articular surfaces
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
AU2009246474B2 (en) 2008-05-12 2015-04-16 Conformis, Inc. Devices and methods for treatment of facet and other joints
GB0812631D0 (en) * 2008-07-10 2008-08-20 Imp Innovations Ltd Modular knee implants
US8808303B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
US9017334B2 (en) 2009-02-24 2015-04-28 Microport Orthopedics Holdings Inc. Patient specific surgical guide locator and mount
US8808297B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
BRPI1014917A2 (pt) 2009-04-16 2016-04-19 Conformis Inc "dispositivos de artroplastia de junta específica para páciente para reparo de ligamento"
WO2010121246A1 (en) 2009-04-17 2010-10-21 Arthrosurface Incorporated Glenoid resurfacing system and method
US10945743B2 (en) 2009-04-17 2021-03-16 Arthrosurface Incorporated Glenoid repair system and methods of use thereof
WO2010121250A1 (en) 2009-04-17 2010-10-21 Arthrosurface Incorporated Glenoid resurfacing system and method
CA2782137A1 (en) 2009-12-11 2011-06-16 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
CA2792048A1 (en) 2010-03-05 2011-09-09 Arthrosurface Incorporated Tibial resurfacing system and method
US9725689B2 (en) 2010-10-08 2017-08-08 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2012112694A2 (en) 2011-02-15 2012-08-23 Conformis, Inc. Medeling, analyzing and using anatomical data for patient-adapted implants. designs, tools and surgical procedures
US9066716B2 (en) 2011-03-30 2015-06-30 Arthrosurface Incorporated Suture coil and suture sheath for tissue repair
WO2013081071A1 (ja) * 2011-12-02 2013-06-06 テルモ株式会社 細胞移植用デバイス
US20130165982A1 (en) 2011-12-22 2013-06-27 Arthrosurface Incorporated System and Method for Bone Fixation
US9364896B2 (en) 2012-02-07 2016-06-14 Medical Modeling Inc. Fabrication of hybrid solid-porous medical implantable devices with electron beam melting technology
US9135374B2 (en) 2012-04-06 2015-09-15 Howmedica Osteonics Corp. Surface modified unit cell lattice structures for optimized secure freeform fabrication
US9180010B2 (en) 2012-04-06 2015-11-10 Howmedica Osteonics Corp. Surface modified unit cell lattice structures for optimized secure freeform fabrication
US9486226B2 (en) 2012-04-18 2016-11-08 Conformis, Inc. Tibial guides, tools, and techniques for resecting the tibial plateau
US9186053B2 (en) * 2012-05-03 2015-11-17 Covidien Lp Methods of using light to repair hernia defects
US9675471B2 (en) 2012-06-11 2017-06-13 Conformis, Inc. Devices, techniques and methods for assessing joint spacing, balancing soft tissues and obtaining desired kinematics for joint implant components
WO2014008126A1 (en) 2012-07-03 2014-01-09 Arthrosurface Incorporated System and method for joint resurfacing and repair
US10016527B2 (en) 2012-10-23 2018-07-10 Orthovita, Inc. Materials and methods for repair of cartilage defects
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US9492200B2 (en) 2013-04-16 2016-11-15 Arthrosurface Incorporated Suture system and method
ES2612659T3 (es) * 2013-09-27 2017-05-18 Skulle Implants Oy Método para recubrir y superficie recubierta
JP6633522B2 (ja) 2013-11-16 2020-01-22 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
US20150250472A1 (en) 2014-03-07 2015-09-10 Arthrosurface Incorporated Delivery System for Articular Surface Implant
US10624748B2 (en) 2014-03-07 2020-04-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US11607319B2 (en) 2014-03-07 2023-03-21 Arthrosurface Incorporated System and method for repairing articular surfaces
JP6783143B2 (ja) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド 培地の受動的補充
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CA2985398C (en) * 2015-05-08 2021-08-03 Reoss Gmbh Device for covering and/or reconstructing a bone defect site; method for producing a cap of a covering device for a bone defect site
US20160331539A1 (en) * 2015-05-12 2016-11-17 Elwha Llc Modifiable implants
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656841A1 (de) 2017-03-31 2020-05-27 Terumo BCT, Inc. Zellexpansion
US11298747B2 (en) 2017-05-18 2022-04-12 Howmedica Osteonics Corp. High fatigue strength porous structure
CA3108761A1 (en) 2017-08-04 2019-02-07 Arthrosurface Incorporated Multicomponent articular surface implant
GB2567173A (en) * 2017-10-04 2019-04-10 Univ Oxford Innovation Ltd Cartilage plug
DE102018113580A1 (de) * 2018-06-07 2019-12-12 Christoph Karl Verfahren und vorrichtung zur herstellung eines implantats
GB2616360B (en) 2019-03-12 2023-11-29 Arthrosurface Inc Humeral and glenoid articular surface implant systems and methods
US11523834B1 (en) 2022-06-20 2022-12-13 University Of Utah Research Foundation Cartilage and bone harvest and delivery system and methods
US11660194B1 (en) 2022-06-20 2023-05-30 University Of Utah Research Foundation Cartilage and bone harvest and delivery system and methods

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH632922A5 (en) 1978-10-06 1982-11-15 Sulzer Ag Anchorage pin for bone implants
EP0034912B1 (de) 1980-02-21 1983-08-17 J. & P. Coats, Limited Vorrichtung zur Behandlung von beschädigten Oberflächen menschlicher Gelenke
US4649918A (en) * 1980-09-03 1987-03-17 Custom Medical Devices, Inc. Bone core removing tool
US4553272A (en) 1981-02-26 1985-11-19 University Of Pittsburgh Regeneration of living tissues by growth of isolated cells in porous implant and product thereof
US4393874A (en) 1982-04-26 1983-07-19 Telectronics Pty. Ltd. Bradycardia event counting and reporting pacer
IL68218A (en) * 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US4559936A (en) * 1983-09-29 1985-12-24 Hill Edward B Bone plugging apparatus
EP0160025B1 (de) * 1983-10-20 1989-12-13 KETHARANATHAN, Vettivetpillai Biomaterial
US4620327A (en) 1984-07-05 1986-11-04 Caplan Arnold I Process of adapting soluble bone protein for use in stimulating osteoinduction
US4789663A (en) * 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
US4877020A (en) * 1984-11-30 1989-10-31 Vich Jose M O Apparatus for bone graft
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US5902741A (en) 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US5041138A (en) * 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
US5736372A (en) 1986-11-20 1998-04-07 Massachusetts Institute Of Technology Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
NL8700113A (nl) * 1987-01-19 1988-08-16 Groningen Science Park Entstuk, geschikt voor behandeling door reconstructieve chirurgie, met weefsel specifieke porositeit, alsmede werkwijze ter vervaardiging van het entstuk.
GB8705985D0 (en) 1987-03-13 1987-04-15 Geistlich Soehne Ag Dressings
US4846835A (en) * 1987-06-15 1989-07-11 Grande Daniel A Technique for healing lesions in cartilage
US5258043A (en) 1987-07-20 1993-11-02 Regen Corporation Method for making a prosthetic intervertebral disc
US5306311A (en) 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US5158574A (en) 1987-07-20 1992-10-27 Regen Corporation Prosthetic meniscus
US5116374A (en) 1989-03-02 1992-05-26 Regen Corporation Prosthetic meniscus
CA1329089C (en) 1987-09-02 1994-05-03 Russell Warren Surgical fastener
NZ226170A (en) 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor
CA1339083C (en) 1987-11-13 1997-07-29 Steven R. Jefferies Bone repair material and delayed drug delivery system
JP2645098B2 (ja) * 1988-09-06 1997-08-25 テルモ株式会社 抗菌剤含有人工皮膚およびその製造法
JP2820415B2 (ja) * 1988-03-14 1998-11-05 ティーエイチエム・バイオメディカル・インコーポレイテッド 生分解性および骨形成性を有する移植骨片代用組成体
US5201745A (en) * 1988-03-15 1993-04-13 Imedex Visceral surgery patch
US4975526A (en) 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US5053050A (en) * 1988-04-29 1991-10-01 Samuel Itay Compositions for repair of cartilage and bone
US4904259A (en) * 1988-04-29 1990-02-27 Samuel Itay Compositions and methods for repair of cartilage and bone
US5108436A (en) 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
IE61346B1 (en) 1988-11-02 1994-11-02 Genentech Inc A permeable material to fit around the teeth or gums of a mammal
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5092883A (en) * 1988-12-28 1992-03-03 Eppley Barry L Method for promoting soft connective tissue growth and repair in mammals
WO1990009783A1 (en) 1989-02-22 1990-09-07 Massachusetts Institute Of Technology Delivery system for controlled release of bioactive factors
WO1990013302A1 (en) 1989-04-28 1990-11-15 Brigham And Women's Hospital Novel materials and methods for guided tissue regeneration
US5062845A (en) * 1989-05-10 1991-11-05 Spine-Tech, Inc. Method of making an intervertebral reamer
US5129906A (en) 1989-09-08 1992-07-14 Linvatec Corporation Bioabsorbable tack for joining bodily tissue and in vivo method and apparatus for deploying same
US5067964A (en) * 1989-12-13 1991-11-26 Stryker Corporation Articular surface repair
US5019108A (en) * 1990-02-02 1991-05-28 Bertin Kim C Modular implant
US6413511B1 (en) * 1990-12-20 2002-07-02 University Of Pittsburgh Of The Commonwealth System Of Higher Education Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5853746A (en) * 1991-01-31 1998-12-29 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
US5206028A (en) 1991-02-11 1993-04-27 Li Shu Tung Dense collagen membrane matrices for medical uses
SE9101853D0 (sv) * 1991-06-17 1991-06-17 Jonas Wadstroem Improved tissue ashesive
FR2679778B1 (fr) 1991-08-02 1995-07-07 Coletica Utilisation de collagene reticule par un agent de reticulation pour la fabrication d'une membrane suturable, biocompatible, a resorption lente, ainsi qu'une telle membrane.
US5259835A (en) * 1991-08-29 1993-11-09 Tri-Point Medical L.P. Wound closure means and method using flowable adhesive
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
IL100721A (en) * 1992-01-21 1996-12-05 Milo Simcha Punch for opening passages between two compartments
CA2117379C (en) * 1992-02-14 1999-11-16 Kypriacos A. Athanasiou Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5326357A (en) 1992-03-18 1994-07-05 Mount Sinai Hospital Corporation Reconstituted cartridge tissue
WO1994000484A1 (en) * 1992-06-22 1994-01-06 Young Henry E Scar inhibitory factor and use thereof
WO1994009118A1 (en) 1992-10-13 1994-04-28 The General Hospital Corporation Immortalized human chondrocytes
US5455597A (en) * 1992-12-29 1995-10-03 Canon Kabushiki Kaisha Image-forming apparatus, and designation of electron beam diameter at image-forming member in image-forming apparatus
DE4300039C1 (de) 1993-01-04 1994-06-09 Imz Fertigung Vertrieb Befestigungsnagel und Setzwerkzeug hierfür
US5514378A (en) * 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
DE4306661C2 (de) 1993-03-03 1995-04-20 Michael Dipl Biol Sittinger Verfahren zum Herstellen eines Implantates aus Zellkulturen
DE4431598C2 (de) 1993-03-03 1997-03-20 Michael Sittinger Verfahren zum Herstellen eines Implantates aus Zellkulturen
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
DE4317448A1 (de) * 1993-05-19 1994-11-24 Gross Ulrich Gelenkflächenersatz
CA2130295A1 (en) 1993-08-26 1995-02-27 Richard A. Berg Ionically crosslinked glycosaminoglycan gels for soft tissue augmentation and drug delivery
US5423858A (en) 1993-09-30 1995-06-13 United States Surgical Corporation Septoplasty fasteners and device for applying same
GB9400163D0 (en) 1994-01-06 1994-03-02 Geistlich Soehne Ag Membrane
US5354283A (en) 1994-01-07 1994-10-11 Little Rapids Corporation Trocar retention apparatus
CA2142209A1 (en) 1994-03-29 1995-09-30 George H. Chu Collagen implants having improved tensile properties
AU2435495A (en) * 1994-05-05 1995-11-29 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
US5858781A (en) * 1994-05-13 1999-01-12 Matyas; John R. Method of tissue transfer and retrieval
EP0692227A1 (de) 1994-07-11 1996-01-17 SULZER Medizinaltechnik AG Flächiges Implantat
EP0804127A1 (de) 1994-07-28 1997-11-05 Ivan Vesely Bioprosthetische implantate sowie herstellungs- und gebrauchsverfahren
US5769899A (en) 1994-08-12 1998-06-23 Matrix Biotechnologies, Inc. Cartilage repair unit
DE4425456A1 (de) * 1994-09-07 1996-03-21 Matthias Dr Med Honl Radialparalleles Knochensägeblatt
US5569252A (en) 1994-09-27 1996-10-29 Justin; Daniel F. Device for repairing a meniscal tear in a knee and method
US6080194A (en) * 1995-02-10 2000-06-27 The Hospital For Joint Disease Orthopaedic Institute Multi-stage collagen-based template or implant for use in the repair of cartilage lesions
US5713374A (en) * 1995-02-10 1998-02-03 The Hospital For Joint Diseases Orthopaedic Institute Fixation method for the attachment of wound repair materials to cartilage defects
GB9503492D0 (en) 1995-02-22 1995-04-12 Ed Geistlich S Hne A G F R Che Chemical product
GB9721585D0 (en) 1997-10-10 1997-12-10 Geistlich Soehne Ag Chemical product
US6132463A (en) * 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
WO1997004665A1 (en) 1995-07-31 1997-02-13 Alta Spinner Australia Pty. Limited Surface moisture removal from food products
US5659252A (en) * 1995-08-25 1997-08-19 Sony Corporation Apparatus and method for detecting arcing in a CRT
EP0801676A2 (de) 1995-10-20 1997-10-22 Michael Sittinger Neue künstliche gewebe, verfahren zu ihrer herstellung und ihre verwendung
DE19540487A1 (de) 1995-10-20 1997-04-24 Olaf Schultz Zellinteraktionssystem zur Induktion künstlicher Gewebe
DE19601477C2 (de) 1996-01-17 1999-12-16 Axel Kirsch Befestigungsnagel
US5842477A (en) 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
DE19654884C2 (de) 1996-03-04 1999-07-29 Kirsch Axel Formkörper
US6242247B1 (en) 1996-06-04 2001-06-05 Sulzer Orthopedics Ltd. Method for making cartilage and implants
US5989269A (en) * 1996-08-30 1999-11-23 Vts Holdings L.L.C. Method, instruments and kit for autologous transplantation
EP0842670A1 (de) 1996-11-13 1998-05-20 Katsunari Nishihara Biomedizinische Materialien
DE19648876C2 (de) 1996-11-16 1999-10-07 Will Minuth Verfahren zum Herstellen eines natürlichen Implantats
US6187053B1 (en) 1996-11-16 2001-02-13 Will Minuth Process for producing a natural implant
AU6654598A (en) 1997-02-13 1998-09-08 Benedict, James A. Implantable collagen-containing putty material
DE19957388A1 (de) 1999-11-24 2001-06-13 Michael Sittinger Chondroinduktive und implantierbare Substrate zur Knorpelheilung und -protektion
DE10006822A1 (de) 2000-02-08 2001-08-23 Michael Sittinger Künstliche Knochenchips, Verfahren zu ihrer Herstellung und ihre Verwendung

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