DE29921606U1 - Cartridge for a device for carrying out chemical or biological reactions - Google Patents

Cartridge for a device for carrying out chemical or biological reactions

Info

Publication number
DE29921606U1
DE29921606U1 DE29921606U DE29921606U DE29921606U1 DE 29921606 U1 DE29921606 U1 DE 29921606U1 DE 29921606 U DE29921606 U DE 29921606U DE 29921606 U DE29921606 U DE 29921606U DE 29921606 U1 DE29921606 U1 DE 29921606U1
Authority
DE
Germany
Prior art keywords
cartridge
cartridge according
wall
elements
plug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE29921606U
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MWG Biotech AG
Original Assignee
MWG Biotech AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MWG Biotech AG filed Critical MWG Biotech AG
Priority to DE29921606U priority Critical patent/DE29921606U1/en
Priority to PCT/EP2000/007791 priority patent/WO2001039876A1/en
Priority to DE20023073U priority patent/DE20023073U1/en
Priority to AU68371/00A priority patent/AU6837100A/en
Publication of DE29921606U1 publication Critical patent/DE29921606U1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00281Individual reactor vessels
    • B01J2219/00286Reactor vessels with top and bottom openings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00319Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks the blocks being mounted in stacked arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00324Reactor vessels in a multiple arrangement the reactor vessels or wells being arranged in plates moving in parallel to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00324Reactor vessels in a multiple arrangement the reactor vessels or wells being arranged in plates moving in parallel to each other
    • B01J2219/00326Movement by rotation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00324Reactor vessels in a multiple arrangement the reactor vessels or wells being arranged in plates moving in parallel to each other
    • B01J2219/00328Movement by linear translation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • B01J2219/00423Means for dispensing and evacuation of reagents using filtration, e.g. through porous frits
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/0059Sequential processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Description

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßtThe description text was not recorded electronically

Claims (15)

1. Kartusche für eine Vorrichtung zur Durchführung chemischer oder biologischer Reaktionen, insbesondere für eine Vorrichtung zum Synthetisieren von Oligonukleo­ tiden, mit einem Hohlkörper (7), der mit einem zum Ankoppeln von Nukleotiden ge­ eigneten Trägermaterial (12) gefüllt ist, wobei an zwei sich gegenüberliegenden Seiten des Hohlkörpers (7) jeweils eine Öffnung vorgesehen ist.1. Cartridge for a device for carrying out chemical or biological Reactions, in particular for a device for synthesizing oligonucleo tiden, with a hollow body (7) with a ge for coupling nucleotides suitable carrier material (12) is filled, wherein an opening on each of two opposite sides of the hollow body (7) is provided. 2. Kartusche nach Anspruch 1, dadurch gekennzeichnet, daß angrenzend an die Öffnungen jeweils eine Fritte (11, 13) angeordnet ist.2. Cartridge according to claim 1, characterized, that a frit (11, 13) is arranged adjacent to the openings. 3. Kartusche nach Anspruch 1 oder 2, dadurch gekennzeichnet, daß an das Trägermaterial (12) Nukleotide gekoppelt sind, an welche weitere Nu­ kleotide zur Ausbildung eines Oligonukleotids angekoppelt werden können.3. A cartridge according to claim 1 or 2, characterized, that nucleotides are coupled to the carrier material (12), to which further nu kleotide can be coupled to form an oligonucleotide. 4. Kartusche nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß der Hohlkörper (7) aus einem dünnwandigen, zylindrischen Körper ausgebildet ist, wobei der Hohlkörper (7) eine Bodenwandung (9) aufweist, in die eine der beiden Öffnungen eingebracht ist, und die andere Öffnung durch eine Mantelwandung (8) des zylindrischen Hohlkörpers (7) begrenzt ist. 4. Cartridge according to one of claims 1 to 3, characterized, that the hollow body (7) is formed from a thin-walled, cylindrical body is, the hollow body (7) has a bottom wall (9) into which one of the two Openings are introduced, and the other opening through a jacket wall (8) of the cylindrical hollow body (7) is limited.   5. Kartusche nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß der Hohlkörper (7) mit einem elastischen Element (22; 30) derart versehen ist, daß die Höhe (H) der Kartusche im unbelasteten Zustand etwas größer ist als eine Ausnehmung zur Aufnahme der Kartusche (6) in einer Vorrichtung zur Durchführung chemischer oder biologischer Reaktionen, so daß bei Beaufschlagung der Ausneh­ mung mit einem oder mehreren weiteren Elementen (1, 3), die Durchgänge (4) zum Zu- bzw. Ableiten von Chemikalien aufweisen, die Kartusche (6) gegen die weiteren Elemente (1, 3) gepreßt wird und dicht mit diesen abschließt.5. Cartridge according to one of claims 1 to 3, characterized, that the hollow body (7) is provided with an elastic element (22; 30) such that the height (H) of the cartridge is slightly larger than one in the unloaded state Recess for receiving the cartridge (6) in a device for implementation chemical or biological reactions, so that when the Ausneh mung with one or more further elements (1, 3), the passages (4) to Chemicals are supplied or removed, the cartridge (6) against the others Elements (1, 3) is pressed and seals them tightly. 6. Kartusche nach Anspruch 5, dadurch gekennzeichnet, daß das elastische Element ein O-Ring (22; 30) ist.6. A cartridge according to claim 5, characterized, that the elastic element is an O-ring (22; 30). 7. Kartusche nach Anspruch 5 oder 6, dadurch gekennzeichnet, daß das Basisteil (14) zylinderförmig mit einer Mantel- und einer Bodenwandung (16, 17) ausgebildet ist.7. A cartridge according to claim 5 or 6, characterized, that the base part (14) is cylindrical with a jacket and a bottom wall (16, 17) is formed. 8. Kartusche nach Anspruch 7, dadurch gekennzeichnet, daß der Deckel (15) eine scheibenförmige Deckelwandung (20) und eine an der Dec­ kelwandung (20) ausgebildete zylinderförmige Steckwandung (21) aufweist, wobei die Steckwandung (21) und die Mantelwandung (16) des Basisteils (14) etwa form­ schlüssig ineinandergreifen.8. A cartridge according to claim 7, characterized, that the cover (15) has a disc-shaped cover wall (20) and one on the Dec kelwandung (20) formed cylindrical plug-in wall (21), wherein the plug-in wall (21) and the jacket wall (16) of the base part (14) approximately form interlock. 9. Kartusche nach Anspruch 8, dadurch gekennzeichnet, daß zwischen der Steckwandung (21) des Deckels (15) und der Mantelwandung des Basisteils ein Element zur Ausbildung eines Reibschlusses, wie z. B. ein O-Ring (23), eingesetzt ist. 9. A cartridge according to claim 8, characterized, that between the plug-in wall (21) of the cover (15) and the jacket wall of the Base part an element for forming a frictional engagement, such as. B. an O-ring (23), is inserted.   10. Kartusche nach Anspruch 8 oder 9, dadurch gekennzeichnet, daß die Steckwandung (21) und/oder ein Bereich der Mantelwandung (16) in elasti­ sche Steckarme (28) unterteilt ist.10. A cartridge according to claim 8 or 9, characterized, that the plug-in wall (21) and / or a region of the jacket wall (16) in elasti cal plug-in arms (28) is divided. 11. Kartusche nach einen der Ansprüche 8 bis 10, dadurch gekennzeichnet, daß die Steckarme (21) und/oder die Mantelwandung (16) mit Rastelementen zum Verrasten des Deckels (15) auf dem Basisteil (14) ausgebildet sind.11. Cartridge according to one of claims 8 to 10, characterized, that the plug-in arms (21) and / or the jacket wall (16) with locking elements for Locking the cover (15) on the base part (14) are formed. 12. Kartusche nach einem der Ansprüche 8 bis 11, dadurch gekennzeichnet, daß ein O-Ring (31) zwischen dem Deckel (15) und dem Basisteil (14) angrenzend an der Außenfläche der Kartusche (6) derart angeordnet ist, daß bei Belastung des O-Rings (31) dieser an der Außenfläche vorsteht, so daß ein Reibschluß in einer Ausnehmung zum Aufnehmen der Kartusche erzeugt werden kann.12. Cartridge according to one of claims 8 to 11, characterized, that an O-ring (31) between the cover (15) and the base part (14) adjacent is arranged on the outer surface of the cartridge (6) such that when the O-rings (31) protrudes on the outer surface, so that a frictional engagement in one Recess for receiving the cartridge can be generated. 13. Kartusche nach einem der Ansprüche 1 bis 11, dadurch gekennzeichnet, daß die Kartusche an ihrer Umfangsfläche mit einem Reibschlußmittel und/oder Formschlußmittel versehen ist, das einen Reibschluß und/oder Formschluß mit einer Ausnehmung zum Aufnehmen der Kartusche erzeugen kann.13. Cartridge according to one of claims 1 to 11, characterized, that the cartridge on its peripheral surface with a frictional engagement means and / or Form-locking means is provided, the frictional engagement and / or positive engagement with a Can create recess for receiving the cartridge. 14. Vorrichtung zum Synthetisieren von Oligonukleotiden, mit einem Element (2), das mehrere Ausnehmungen (5) zur Aufnahme von nach ei­ nem der Ansprüche 1 bis 9 ausgebildeten Kartuschen (6) aufweist, wobei die Kartu­ schen (6) Reaktionskammern der Vorrichtung begrenzen.14. Device for synthesizing oligonucleotides, with an element (2) which has a plurality of recesses (5) for receiving ei nem of claims 1 to 9 trained cartridges (6), the cartridge limit (6) reaction chambers of the device. 15. Vorrichtung nach Anspruch 14, dadurch gekennzeichnet, daß angrenzend an dem die Ausnehmungen (5) aufweisenden Element (2) weitere Elemente (1, 3) vorgesehen sind, die Durchgänge (4) zum Zu- bzw. Ableiten von Chemikalien aufweisen, wobei zumindest eines der drei Elemente (1, 2, 3) verschiebbar gegenüber den anderen beiden Elementen (1, 2, 3) angeordnet ist, und eine Einrichtung vorgesehen ist, mit welcher die drei Elemente (1, 2, 3) lösbar anein­ andergedrückt werden können.15. The apparatus according to claim 14, characterized, that adjacent to the recesses (5) having element (2) more Elements (1, 3) are provided, the passages (4) for supplying and discharging Have chemicals, at least one of the three elements (1, 2, 3) being displaceable  opposite the other two elements (1, 2, 3) is arranged, and a device is provided with which the three elements (1, 2, 3) are detachably attached to one another can be pressed.
DE29921606U 1999-12-03 1999-12-03 Cartridge for a device for carrying out chemical or biological reactions Expired - Lifetime DE29921606U1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE29921606U DE29921606U1 (en) 1999-12-03 1999-12-03 Cartridge for a device for carrying out chemical or biological reactions
PCT/EP2000/007791 WO2001039876A1 (en) 1999-12-03 2000-08-10 Cartridge for a device for carrying out chemical or biological reactions
DE20023073U DE20023073U1 (en) 1999-12-03 2000-08-10 Cartridge for a device for carrying out chemical or biological reactions
AU68371/00A AU6837100A (en) 1999-12-03 2000-08-10 Cartridge for a device for carrying out chemical or biological reactions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE29921606U DE29921606U1 (en) 1999-12-03 1999-12-03 Cartridge for a device for carrying out chemical or biological reactions

Publications (1)

Publication Number Publication Date
DE29921606U1 true DE29921606U1 (en) 2001-04-19

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DE29921606U Expired - Lifetime DE29921606U1 (en) 1999-12-03 1999-12-03 Cartridge for a device for carrying out chemical or biological reactions
DE20023073U Expired - Lifetime DE20023073U1 (en) 1999-12-03 2000-08-10 Cartridge for a device for carrying out chemical or biological reactions

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DE20023073U Expired - Lifetime DE20023073U1 (en) 1999-12-03 2000-08-10 Cartridge for a device for carrying out chemical or biological reactions

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AU (1) AU6837100A (en)
DE (2) DE29921606U1 (en)
WO (1) WO2001039876A1 (en)

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US20220126259A1 (en) * 2020-10-28 2022-04-28 CSBio Instrumentation Co. Peptide synthesis instrumentation

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US4483964A (en) * 1983-06-20 1984-11-20 Chiron Corporation Reactor system and method for polynucleotide synthesis
US4517338A (en) * 1983-06-20 1985-05-14 Chiron Corporation Multiple reactor system and method for polynucleotide synthesis
WO1988005074A1 (en) * 1987-01-06 1988-07-14 Baylor College Of Medicine Porous wafer for segmented synthesis of biopolymers
DE3905448C1 (en) * 1989-02-22 1990-10-18 Berthold Dr. 7940 Emeringen De Singruen Process for the synthesis of macromolecules of specific chain length, structure and sequence
WO1992015867A1 (en) * 1991-03-06 1992-09-17 Rhone-Poulenc Rorer S.A. Method and device for heterogeneous phase synthesis of macromolecules such as peptides, polynucleotides or oligosaccharides
US5405585A (en) * 1992-07-06 1995-04-11 Beckman Instruments, Inc. Fluid delivery system utilizing multiple port valve
US5429807A (en) * 1993-10-28 1995-07-04 Beckman Instruments, Inc. Method and apparatus for creating biopolymer arrays on a solid support surface
US5681534A (en) * 1995-07-20 1997-10-28 Neves; Richard S. High throughput oligonucleotide synthesizer
DE19819735A1 (en) * 1998-05-02 1999-11-04 Novartis Ag Device and method for producing an arrangement of chain molecules on a carrier material

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JPS6130597A (en) * 1984-07-20 1986-02-12 Nippon Zeon Co Ltd Device for synthesizing polynucleotide
DE4206488C2 (en) * 1992-03-02 1993-12-23 Deutsches Krebsforsch Device for carrying out chemical reactions taking place simultaneously or sequentially
KR20020003188A (en) * 1998-12-30 2002-01-10 볼프강 하임버그 apparatus for the conduct of chemical reactions

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4483964A (en) * 1983-06-20 1984-11-20 Chiron Corporation Reactor system and method for polynucleotide synthesis
US4517338A (en) * 1983-06-20 1985-05-14 Chiron Corporation Multiple reactor system and method for polynucleotide synthesis
WO1988005074A1 (en) * 1987-01-06 1988-07-14 Baylor College Of Medicine Porous wafer for segmented synthesis of biopolymers
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