US5206018A
(en)
*
|
1978-11-03 |
1993-04-27 |
Ayerst, Mckenna & Harrison, Inc. |
Use of rapamycin in treatment of tumors
|
EP0429436A3
(en)
*
|
1985-12-06 |
1991-12-27 |
The University Of Kansas |
Prodrugs of rapamycin
|
US4650803A
(en)
*
|
1985-12-06 |
1987-03-17 |
University Of Kansas |
Prodrugs of rapamycin
|
US5100899A
(en)
*
|
1989-06-06 |
1992-03-31 |
Roy Calne |
Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
|
JPH04230389A
(ja)
*
|
1990-07-16 |
1992-08-19 |
American Home Prod Corp |
ラパマイシン誘導体
|
US5120726A
(en)
*
|
1991-03-08 |
1992-06-09 |
American Home Products Corporation |
Rapamycin hydrazones
|
US5023264A
(en)
*
|
1990-07-16 |
1991-06-11 |
American Home Products Corporation |
Rapamycin oximes
|
US5023263A
(en)
*
|
1990-08-09 |
1991-06-11 |
American Home Products Corporation |
42-oxorapamycin
|
US5023262A
(en)
*
|
1990-08-14 |
1991-06-11 |
American Home Products Corporation |
Hydrogenated rapamycin derivatives
|
US5130307A
(en)
*
|
1990-09-28 |
1992-07-14 |
American Home Products Corporation |
Aminoesters of rapamycin
|
US5378696A
(en)
*
|
1990-09-19 |
1995-01-03 |
American Home Products Corporation |
Rapamycin esters
|
US5221670A
(en)
*
|
1990-09-19 |
1993-06-22 |
American Home Products Corporation |
Rapamycin esters
|
US5358944A
(en)
*
|
1990-09-19 |
1994-10-25 |
American Home Products Corporation |
Rapamycin esters for treating transplantation rejection
|
PT98990A
(pt)
*
|
1990-09-19 |
1992-08-31 |
American Home Prod |
Processo para a preparacao de esteres de acidos carboxilicos de rapamicina
|
US5233036A
(en)
*
|
1990-10-16 |
1993-08-03 |
American Home Products Corporation |
Rapamycin alkoxyesters
|
US5120842A
(en)
*
|
1991-04-01 |
1992-06-09 |
American Home Products Corporation |
Silyl ethers of rapamycin
|
US5100883A
(en)
*
|
1991-04-08 |
1992-03-31 |
American Home Products Corporation |
Fluorinated esters of rapamycin
|
JPH05112573A
(ja)
*
|
1991-04-17 |
1993-05-07 |
American Home Prod Corp |
ラパマイシンのカルバミン酸エステル類
|
US5194447A
(en)
*
|
1992-02-18 |
1993-03-16 |
American Home Products Corporation |
Sulfonylcarbamates of rapamycin
|
US5118678A
(en)
*
|
1991-04-17 |
1992-06-02 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5091389A
(en)
*
|
1991-04-23 |
1992-02-25 |
Merck & Co., Inc. |
Lipophilic macrolide useful as an immunosuppressant
|
US5138051A
(en)
*
|
1991-08-07 |
1992-08-11 |
American Home Products Corporation |
Rapamycin analogs as immunosuppressants and antifungals
|
US5102876A
(en)
*
|
1991-05-07 |
1992-04-07 |
American Home Products Corporation |
Reduction products of rapamycin
|
US5776943A
(en)
*
|
1991-05-14 |
1998-07-07 |
American Home Products Corporation |
Rapamycin metabolites
|
US5118677A
(en)
*
|
1991-05-20 |
1992-06-02 |
American Home Products Corporation |
Amide esters of rapamycin
|
EP0516347A1
(de)
*
|
1991-05-29 |
1992-12-02 |
American Home Products Corporation |
Rapamycinderivate
|
ZA924953B
(en)
*
|
1991-07-25 |
1993-04-28 |
Univ Louisville Res Found |
Method of treating ocular inflammation
|
US5162333A
(en)
*
|
1991-09-11 |
1992-11-10 |
American Home Products Corporation |
Aminodiesters of rapamycin
|
US5151413A
(en)
*
|
1991-11-06 |
1992-09-29 |
American Home Products Corporation |
Rapamycin acetals as immunosuppressant and antifungal agents
|
US5164399A
(en)
*
|
1991-11-18 |
1992-11-17 |
American Home Products Corporation |
Rapamycin pyrazoles
|
US5262424A
(en)
*
|
1992-02-18 |
1993-11-16 |
American Home Products Corporation |
Composition of sulfonylcarbamates of rapamycin and method of treating diseases requiring immunosuppression therewith
|
US5177203A
(en)
*
|
1992-03-05 |
1993-01-05 |
American Home Products Corporation |
Rapamycin 42-sulfonates and 42-(N-carboalkoxy) sulfamates useful as immunosuppressive agents
|
ZA935111B
(en)
*
|
1992-07-17 |
1994-02-04 |
Smithkline Beecham Corp |
Rapamycin derivatives
|
US5256790A
(en)
*
|
1992-08-13 |
1993-10-26 |
American Home Products Corporation |
27-hydroxyrapamycin and derivatives thereof
|
CA2106034A1
(en)
*
|
1992-09-24 |
1994-03-25 |
Ralph J. Russo |
21-norrapamycin
|
US5480989A
(en)
*
|
1992-10-13 |
1996-01-02 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5480988A
(en)
*
|
1992-10-13 |
1996-01-02 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5434260A
(en)
*
|
1992-10-13 |
1995-07-18 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5489680A
(en)
*
|
1992-10-13 |
1996-02-06 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5302584A
(en)
*
|
1992-10-13 |
1994-04-12 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5262423A
(en)
*
|
1992-10-29 |
1993-11-16 |
American Home Products Corporation |
Rapamycin arylcarbonyl and alkoxycarbonyl carbamates as immunosuppressive and antifungal agents
|
US5260300A
(en)
*
|
1992-11-19 |
1993-11-09 |
American Home Products Corporation |
Rapamycin carbonate esters as immuno-suppressant agents
|
US5349060A
(en)
*
|
1993-01-07 |
1994-09-20 |
American Home Products Corporation |
Rapamycin 31-ester with N,N-dimethylglycine derivatives useful as immunosuppressive agents
|
US5252579A
(en)
*
|
1993-02-16 |
1993-10-12 |
American Home Products Corporation |
Macrocyclic immunomodulators
|
DE69430060T2
(de)
|
1993-04-23 |
2002-11-07 |
Abbott Lab |
Antikörper von rapamycinen mit offenem ring
|
US5504091A
(en)
*
|
1993-04-23 |
1996-04-02 |
American Home Products Corporation |
Biotin esters of rapamycin
|
US7279561B1
(en)
*
|
1993-04-23 |
2007-10-09 |
Wyeth |
Anti-rapamycin monoclonal antibodies
|
USRE37421E1
(en)
|
1993-07-16 |
2001-10-23 |
Smithkline Beecham Corporation |
Rapamycin derivatives
|
US5387680A
(en)
*
|
1993-08-10 |
1995-02-07 |
American Home Products Corporation |
C-22 ring stabilized rapamycin derivatives
|
US5373014A
(en)
*
|
1993-10-08 |
1994-12-13 |
American Home Products Corporation |
Rapamycin oximes
|
US5391730A
(en)
*
|
1993-10-08 |
1995-02-21 |
American Home Products Corporation |
Phosphorylcarbamates of rapamycin and oxime derivatives thereof
|
US5378836A
(en)
*
|
1993-10-08 |
1995-01-03 |
American Home Products Corporation |
Rapamycin oximes and hydrazones
|
US5385910A
(en)
*
|
1993-11-22 |
1995-01-31 |
American Home Products Corporation |
Gem-distributed esters of rapamycin
|
US5385909A
(en)
*
|
1993-11-22 |
1995-01-31 |
American Home Products Corporation |
Heterocyclic esters of rapamycin
|
US5385908A
(en)
*
|
1993-11-22 |
1995-01-31 |
American Home Products Corporation |
Hindered esters of rapamycin
|
US5389639A
(en)
*
|
1993-12-29 |
1995-02-14 |
American Home Products Company |
Amino alkanoic esters of rapamycin
|
US5525610A
(en)
*
|
1994-03-31 |
1996-06-11 |
American Home Products Corporation |
42-Epi-rapamycin and pharmaceutical compositions thereof
|
US5362718A
(en)
|
1994-04-18 |
1994-11-08 |
American Home Products Corporation |
Rapamycin hydroxyesters
|
US5463048A
(en)
*
|
1994-06-14 |
1995-10-31 |
American Home Products Corporation |
Rapamycin amidino carbamates
|
WO1996006847A1
(en)
*
|
1994-08-31 |
1996-03-07 |
Pfizer Inc. |
Process for preparing demethylrapamycins
|
US5491231A
(en)
*
|
1994-11-28 |
1996-02-13 |
American Home Products Corporation |
Hindered N-oxide esters of rapamycin
|
US5563145A
(en)
*
|
1994-12-07 |
1996-10-08 |
American Home Products Corporation |
Rapamycin 42-oximes and hydroxylamines
|
US5780462A
(en)
*
|
1995-12-27 |
1998-07-14 |
American Home Products Corporation |
Water soluble rapamycin esters
|
US6258823B1
(en)
*
|
1996-07-12 |
2001-07-10 |
Ariad Pharmaceuticals, Inc. |
Materials and method for treating or preventing pathogenic fungal infection
|
US5922730A
(en)
*
|
1996-09-09 |
1999-07-13 |
American Home Products Corporation |
Alkylated rapamycin derivatives
|
US20030129215A1
(en)
*
|
1998-09-24 |
2003-07-10 |
T-Ram, Inc. |
Medical devices containing rapamycin analogs
|
US6015815A
(en)
*
|
1997-09-26 |
2000-01-18 |
Abbott Laboratories |
Tetrazole-containing rapamycin analogs with shortened half-lives
|
US7399480B2
(en)
*
|
1997-09-26 |
2008-07-15 |
Abbott Laboratories |
Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices
|
US20060198867A1
(en)
*
|
1997-09-25 |
2006-09-07 |
Abbott Laboratories, Inc. |
Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy
|
US6890546B2
(en)
*
|
1998-09-24 |
2005-05-10 |
Abbott Laboratories |
Medical devices containing rapamycin analogs
|
US8257726B2
(en)
*
|
1997-09-26 |
2012-09-04 |
Abbott Laboratories |
Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices
|
US8394398B2
(en)
*
|
1997-09-26 |
2013-03-12 |
Abbott Laboratories |
Methods of administering rapamycin analogs with anti-inflammatories using medical devices
|
US7378105B2
(en)
*
|
1997-09-26 |
2008-05-27 |
Abbott Laboratories |
Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens
|
US8057816B2
(en)
*
|
1997-09-26 |
2011-11-15 |
Abbott Laboratories |
Compositions and methods of administering paclitaxel with other drugs using medical devices
|
US7357942B2
(en)
*
|
1997-09-26 |
2008-04-15 |
Abbott Laboratories |
Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens
|
US8257725B2
(en)
*
|
1997-09-26 |
2012-09-04 |
Abbott Laboratories |
Delivery of highly lipophilic agents via medical devices
|
US6015809A
(en)
*
|
1998-08-17 |
2000-01-18 |
American Home Products Corporation |
Photocyclized rapamycin
|
US7960405B2
(en)
*
|
1998-09-24 |
2011-06-14 |
Abbott Laboratories |
Compounds and methods for treatment and prevention of diseases
|
US7455853B2
(en)
*
|
1998-09-24 |
2008-11-25 |
Abbott Cardiovascular Systems Inc. |
Medical devices containing rapamycin analogs
|
US8257724B2
(en)
*
|
1998-09-24 |
2012-09-04 |
Abbott Laboratories |
Delivery of highly lipophilic agents via medical devices
|
US20060240070A1
(en)
*
|
1998-09-24 |
2006-10-26 |
Cromack Keith R |
Delivery of highly lipophilic agents via medical devices
|
US6331547B1
(en)
|
1999-08-18 |
2001-12-18 |
American Home Products Corporation |
Water soluble SDZ RAD esters
|
US7807211B2
(en)
*
|
1999-09-03 |
2010-10-05 |
Advanced Cardiovascular Systems, Inc. |
Thermal treatment of an implantable medical device
|
US6790228B2
(en)
*
|
1999-12-23 |
2004-09-14 |
Advanced Cardiovascular Systems, Inc. |
Coating for implantable devices and a method of forming the same
|
US20070032853A1
(en)
*
|
2002-03-27 |
2007-02-08 |
Hossainy Syed F |
40-O-(2-hydroxy)ethyl-rapamycin coated stent
|
US6277983B1
(en)
|
2000-09-27 |
2001-08-21 |
American Home Products Corporation |
Regioselective synthesis of rapamycin derivatives
|
US6670355B2
(en)
|
2000-06-16 |
2003-12-30 |
Wyeth |
Method of treating cardiovascular disease
|
ATE278421T1
(de)
|
2000-08-11 |
2004-10-15 |
Wyeth Corp |
Verfahren zur behandlung eines östrogenrezeptor positives karzinoms
|
EP1319008B1
(de)
|
2000-09-19 |
2008-10-15 |
Wyeth |
Wasserlösliche rapamycin-ester
|
US6399625B1
(en)
|
2000-09-27 |
2002-06-04 |
Wyeth |
1-oxorapamycins
|
US6440991B1
(en)
|
2000-10-02 |
2002-08-27 |
Wyeth |
Ethers of 7-desmethlrapamycin
|
US6399626B1
(en)
|
2000-10-02 |
2002-06-04 |
Wyeth |
Hydroxyesters of 7-desmethylrapamycin
|
US20040018228A1
(en)
*
|
2000-11-06 |
2004-01-29 |
Afmedica, Inc. |
Compositions and methods for reducing scar tissue formation
|
US7829084B2
(en)
*
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US20080145402A1
(en)
*
|
2001-09-10 |
2008-06-19 |
Abbott Cardiovascular Systems Inc. |
Medical Devices Containing Rapamycin Analogs
|
US20030054042A1
(en)
*
|
2001-09-14 |
2003-03-20 |
Elaine Liversidge |
Stabilization of chemical compounds using nanoparticulate formulations
|
US7682387B2
(en)
|
2002-04-24 |
2010-03-23 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
US6939376B2
(en)
|
2001-11-05 |
2005-09-06 |
Sun Biomedical, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
US20040024450A1
(en)
*
|
2002-04-24 |
2004-02-05 |
Sun Biomedical, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
DE60319118T2
(de)
*
|
2002-07-30 |
2009-02-05 |
Wyeth |
Parenterale formulierungen mit einem rapamycin hydroxyester
|
KR101012605B1
(ko)
|
2002-09-06 |
2011-02-10 |
아보트 러보러터리즈 |
수화 억제제를 포함하는 의료용 장치
|
EP2517730A3
(de)
*
|
2003-01-27 |
2013-01-02 |
Endocyte, Inc. |
Vitaminrezeptorbindende Wirkstofffreisetzungskonjugate
|
US7160867B2
(en)
|
2003-05-16 |
2007-01-09 |
Isotechnika, Inc. |
Rapamycin carbohydrate derivatives
|
US20050118344A1
(en)
|
2003-12-01 |
2005-06-02 |
Pacetti Stephen D. |
Temperature controlled crimping
|
US7585517B2
(en)
*
|
2003-09-18 |
2009-09-08 |
Macusight, Inc. |
Transscleral delivery
|
TW200517114A
(en)
|
2003-10-15 |
2005-06-01 |
Combinatorx Inc |
Methods and reagents for the treatment of immunoinflammatory disorders
|
US7220755B2
(en)
|
2003-11-12 |
2007-05-22 |
Biosensors International Group, Ltd. |
42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
|
US7349971B2
(en)
*
|
2004-02-05 |
2008-03-25 |
Scenera Technologies, Llc |
System for transmitting data utilizing multiple communication applications simultaneously in response to user request without specifying recipient's communication information
|
US20070027523A1
(en)
*
|
2004-03-19 |
2007-02-01 |
Toner John L |
Method of treating vascular disease at a bifurcated vessel using coated balloon
|
AU2005222719B2
(en)
*
|
2004-03-19 |
2011-03-24 |
Abbott Laboratories |
Multiple drug delivery from a balloon and a prosthesis
|
US8431145B2
(en)
|
2004-03-19 |
2013-04-30 |
Abbott Laboratories |
Multiple drug delivery from a balloon and a prosthesis
|
US20100030183A1
(en)
*
|
2004-03-19 |
2010-02-04 |
Toner John L |
Method of treating vascular disease at a bifurcated vessel using a coated balloon
|
BRPI0509852A
(pt)
|
2004-04-14 |
2007-10-23 |
Wyeth Corp |
método para a preparação regioespecìfica dos derivados de 42-éster de rapamicina, preparação regioespecìfica do 42-éster de rapamicina, composição, produto, e, kit farmacêutico
|
ES2313328T3
(es)
*
|
2004-04-14 |
2009-03-01 |
Wyeth |
Procedimiento para la preparacion de 42-esteres de rapamicina y 32-esteres de fk-506 con acido dicarboxilico, precursores para conjugados de rapamicina y anticuerpos.
|
AU2005238493A1
(en)
*
|
2004-04-27 |
2005-11-10 |
Wyeth |
Labeling of rapamycin using rapamycin-specific methylases
|
EP1768692B8
(de)
*
|
2004-07-01 |
2015-06-17 |
Yale University |
Mit wirkstoff beladene polymermaterialien von hoher dichte und mit zielausrichtung
|
EP1789391B1
(de)
|
2004-07-23 |
2017-06-28 |
Endocyte, Inc. |
Zweiwertige linker und konjugate davon
|
MX2007001676A
(es)
*
|
2004-08-10 |
2007-04-12 |
Wyeth Corp |
Derivados de 42-ester de rapamicina con acido 2,2-bis(hidroximetil)propionico y metodos para hacer los mismos.
|
US7901451B2
(en)
*
|
2004-09-24 |
2011-03-08 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
US8313763B2
(en)
*
|
2004-10-04 |
2012-11-20 |
Tolmar Therapeutics, Inc. |
Sustained delivery formulations of rapamycin compounds
|
WO2006041942A2
(en)
*
|
2004-10-04 |
2006-04-20 |
Qlt Usa, Inc. |
Ocular delivery of polymeric delivery formulations
|
AU2005302004A1
(en)
*
|
2004-10-28 |
2006-05-11 |
Wyeth |
Use of an mTOR inhibitor in treatment of uterine leiomyoma
|
US8663639B2
(en)
*
|
2005-02-09 |
2014-03-04 |
Santen Pharmaceutical Co., Ltd. |
Formulations for treating ocular diseases and conditions
|
SI1848431T1
(sl)
*
|
2005-02-09 |
2016-05-31 |
Santen Pharmaceutical Co., Ltd. |
Tekoče formulacije za zdravljenje bolezni ali stanj
|
WO2006089207A2
(en)
*
|
2005-02-18 |
2006-08-24 |
Abraxis Bioscience, Inc. |
Drugs with improved hydrophobicity for incorporation in medical devices
|
GB0503936D0
(en)
*
|
2005-02-25 |
2005-04-06 |
San Raffaele Centro Fond |
Method
|
JP5289935B2
(ja)
*
|
2005-03-16 |
2013-09-11 |
エンドサイト,インコーポレイテッド |
プテロイン酸およびその結合体の合成と精製
|
EP1868663B1
(de)
|
2005-03-23 |
2011-11-16 |
Abbott Laboratories |
Abgabe von stark lipophilen mitteln durch medizinprodukte
|
EP3138531A1
(de)
|
2005-03-23 |
2017-03-08 |
Abbott Laboratories |
Zusammensetzungen und verfahren zur verabreichung von rapamycinanaloga mithilfe von medizinischen vorrichtungen für langzeitwirkung
|
SI2298815T1
(sl)
*
|
2005-07-25 |
2015-08-31 |
Emergent Product Development Seattle, Llc |
Zmanjšanje števila celic b z uporabo molekul, ki se specifično vežejo na cd37 in cd20
|
RU2470668C2
(ru)
*
|
2005-08-19 |
2012-12-27 |
Эндосайт, Инк. |
Конъюгаты лиганда с несколькими лекарственными средствами
|
CA2626326C
(en)
|
2005-11-04 |
2021-02-16 |
Wyeth |
Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
|
US8067433B2
(en)
|
2005-11-09 |
2011-11-29 |
Zalicus Inc. |
Methods, compositions, and kits for the treatment of ophthalmic disorders
|
US20070142422A1
(en)
*
|
2005-12-20 |
2007-06-21 |
Wyeth |
Control of CCI-779 dosage form stability through control of drug substance impurities
|
JP5528708B2
(ja)
|
2006-02-09 |
2014-06-25 |
参天製薬株式会社 |
安定な製剤ならびにそれらを調製および使用する方法
|
US7678901B2
(en)
|
2006-02-28 |
2010-03-16 |
Wyeth |
Rapamycin analogs containing an antioxidant moiety
|
US7622477B2
(en)
*
|
2006-02-28 |
2009-11-24 |
Cordis Corporation |
Isomers and 42-epimers of rapamycin alkyl ether analogs, methods of making and using the same
|
US20070203169A1
(en)
*
|
2006-02-28 |
2007-08-30 |
Zhao Jonathon Z |
Isomers and 42-epimers of rapamycin ester analogs, methods of making and using the same
|
US8222271B2
(en)
*
|
2006-03-23 |
2012-07-17 |
Santen Pharmaceutical Co., Ltd. |
Formulations and methods for vascular permeability-related diseases or conditions
|
US20080051691A1
(en)
*
|
2006-08-28 |
2008-02-28 |
Wyeth |
Implantable shunt or catheter enabling gradual delivery of therapeutic agents
|
JP6049160B2
(ja)
|
2006-09-13 |
2016-12-27 |
エリクシアー メディカル コーポレイション |
大環状ラクトン化合物およびその使用方法
|
WO2008033466A2
(en)
*
|
2006-09-14 |
2008-03-20 |
Combinatorx (Singapore) Pre. Ltd. |
Compositions and methods for treatment of viral diseases
|
WO2008042216A2
(en)
|
2006-09-28 |
2008-04-10 |
Follica, Inc. |
Methods, kits, and compositions for generating new hair follicles and growing hair
|
US20080097591A1
(en)
|
2006-10-20 |
2008-04-24 |
Biosensors International Group |
Drug-delivery endovascular stent and method of use
|
US8067055B2
(en)
*
|
2006-10-20 |
2011-11-29 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method of use
|
US20080103584A1
(en)
*
|
2006-10-25 |
2008-05-01 |
Biosensors International Group |
Temporal Intraluminal Stent, Methods of Making and Using
|
US9700704B2
(en)
|
2006-11-20 |
2017-07-11 |
Lutonix, Inc. |
Drug releasing coatings for balloon catheters
|
US8414526B2
(en)
|
2006-11-20 |
2013-04-09 |
Lutonix, Inc. |
Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
|
US9737640B2
(en)
|
2006-11-20 |
2017-08-22 |
Lutonix, Inc. |
Drug releasing coatings for medical devices
|
US8430055B2
(en)
*
|
2008-08-29 |
2013-04-30 |
Lutonix, Inc. |
Methods and apparatuses for coating balloon catheters
|
US20080175887A1
(en)
|
2006-11-20 |
2008-07-24 |
Lixiao Wang |
Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
|
US8414525B2
(en)
|
2006-11-20 |
2013-04-09 |
Lutonix, Inc. |
Drug releasing coatings for medical devices
|
US8414910B2
(en)
|
2006-11-20 |
2013-04-09 |
Lutonix, Inc. |
Drug releasing coatings for medical devices
|
US20080276935A1
(en)
|
2006-11-20 |
2008-11-13 |
Lixiao Wang |
Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
|
US8425459B2
(en)
|
2006-11-20 |
2013-04-23 |
Lutonix, Inc. |
Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
|
US8998846B2
(en)
|
2006-11-20 |
2015-04-07 |
Lutonix, Inc. |
Drug releasing coatings for balloon catheters
|
US10265407B2
(en)
|
2007-02-15 |
2019-04-23 |
Yale University |
Modular nanodevices for smart adaptable vaccines
|
WO2008101231A2
(en)
|
2007-02-16 |
2008-08-21 |
Endocyte, Inc. |
Methods and compositions for treating and diagnosing kidney disease
|
WO2008109347A2
(en)
*
|
2007-03-02 |
2008-09-12 |
Yale University |
Methods for ex vivo administration of drugs to grafts using polymeric nanoparticles
|
CA2680535C
(en)
|
2007-03-14 |
2016-09-20 |
Endocyte, Inc. |
Binding ligand linked drug delivery conjugates of tubulysins
|
TW200901989A
(en)
|
2007-04-10 |
2009-01-16 |
Wyeth Corp |
Anti-tumor activity of CCI-779 in papillary renal cell cancer
|
US20080265343A1
(en)
*
|
2007-04-26 |
2008-10-30 |
International Business Machines Corporation |
Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
|
JP2008305262A
(ja)
*
|
2007-06-08 |
2008-12-18 |
Konica Minolta Business Technologies Inc |
サーバ及びシンクライアント環境でのプリンタ紹介方法
|
WO2009002993A1
(en)
|
2007-06-25 |
2008-12-31 |
Endocyte, Inc. |
Conjugates containing hydrophilic spacer linkers
|
US9877965B2
(en)
|
2007-06-25 |
2018-01-30 |
Endocyte, Inc. |
Vitamin receptor drug delivery conjugates for treating inflammation
|
AU2008287195A1
(en)
*
|
2007-07-06 |
2009-02-19 |
Emergent Product Development Seattle, Llc |
Binding peptides having a C-terminally disposed specific binding domain
|
KR100930167B1
(ko)
*
|
2007-09-19 |
2009-12-07 |
삼성전기주식회사 |
초광각 광학계
|
US20100048913A1
(en)
|
2008-03-14 |
2010-02-25 |
Angela Brodie |
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
|
CA2719134C
(en)
*
|
2008-03-21 |
2015-06-30 |
The University Of Chicago |
Treatment with opioid antagonists and mtor inhibitors
|
US20090253733A1
(en)
*
|
2008-04-02 |
2009-10-08 |
Biointeractions, Ltd. |
Rapamycin carbonate esters
|
WO2009126944A1
(en)
*
|
2008-04-11 |
2009-10-15 |
Trubion Pharmaceuticals, Inc. |
Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
US20100092479A1
(en)
*
|
2008-08-18 |
2010-04-15 |
Combinatorx (Singapore) Pte. Ltd. |
Compositions and methods for treatment of viral diseases
|
BRPI0919794A2
(pt)
*
|
2008-10-03 |
2015-12-15 |
Elixir Medical Corp |
dispositivo para uso intracorpóreo, e, composto
|
US20120064143A1
(en)
|
2008-11-11 |
2012-03-15 |
The Board Of Regents Of The University Of Texas System |
Inhibition of mammalian target of rapamycin
|
BRPI1008745A2
(pt)
|
2009-02-05 |
2019-09-17 |
Tokai Pharmaceuticals Inc |
pró-fármacos de inibidores esteroidais de cyp17/antiandrogênios
|
AU2010313152A1
(en)
|
2009-10-30 |
2012-04-19 |
Ariad Pharmaceuticals, Inc. |
Methods and compositions for treating cancer
|
WO2015103447A1
(en)
|
2013-12-31 |
2015-07-09 |
Rapamycin Holdings, Llc |
Oral rapamycin nanoparticle preparations and use
|
US9283211B1
(en)
|
2009-11-11 |
2016-03-15 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
US20110130711A1
(en)
*
|
2009-11-19 |
2011-06-02 |
Follica, Inc. |
Hair growth treatment
|
US20110144577A1
(en)
*
|
2009-12-11 |
2011-06-16 |
John Stankus |
Hydrophilic coatings with tunable composition for drug coated balloon
|
US8951595B2
(en)
*
|
2009-12-11 |
2015-02-10 |
Abbott Cardiovascular Systems Inc. |
Coatings with tunable molecular architecture for drug-coated balloon
|
US8480620B2
(en)
*
|
2009-12-11 |
2013-07-09 |
Abbott Cardiovascular Systems Inc. |
Coatings with tunable solubility profile for drug-coated balloon
|
EP2542670A2
(de)
|
2010-03-05 |
2013-01-09 |
President and Fellows of Harvard College |
Zusammensetzungen aus induzierten dentritischen zellen und ihre verwendung
|
EP2694520A1
(de)
*
|
2011-04-01 |
2014-02-12 |
Sandoz AG |
Regioselektive acylierung von rapamycin an der c-42-position
|
EP2532740A1
(de)
|
2011-06-11 |
2012-12-12 |
Michael Schmück |
Antigenspezifische CD4+ und CD8+ zentrale Gedächtnis-T-Zellpräparate für adoptive T-Zelltherapie
|
WO2013013708A1
(en)
|
2011-07-26 |
2013-01-31 |
Fundació Institut D'investigació Biomèdica De Bellvitge |
Treatment of acute rejection in renal transplant
|
WO2013126797A1
(en)
|
2012-02-24 |
2013-08-29 |
Purdue Research Foundation |
Cholecystokinin b receptor targeting for imaging and therapy
|
US20140080175A1
(en)
|
2012-03-29 |
2014-03-20 |
Endocyte, Inc. |
Processes for preparing tubulysin derivatives and conjugates thereof
|
EP2841098A4
(de)
|
2012-04-23 |
2016-03-02 |
Allertein Therapeutics Llc |
Nanopartikel zur behandlung von allergien
|
DK2859001T3
(da)
|
2012-06-08 |
2016-05-30 |
Biotronik Ag |
Rapamycin 40-o-cyklisk kulbrinteestere, sammensætninger og fremgangsmåder
|
US9750728B2
(en)
|
2012-09-29 |
2017-09-05 |
Targeted Therapeutics, Llc |
Method and pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway
|
CN103705925B
(zh)
|
2012-09-29 |
2018-03-30 |
段磊 |
抑制PI3K/AKT/mTOR信号通路的药物组合
|
EP2906214A1
(de)
|
2012-10-12 |
2015-08-19 |
The Board of Regents of The University of Texas System |
Verwendung von mtor-hemmern zur behandlung von vaskulären kognitiven störungen
|
EA201590622A1
(ru)
|
2012-10-16 |
2015-10-30 |
Эндосайт, Инк. |
Конъюгаты для доставки лекарственного средства, содержащие не встречающиеся в природе аминокислоты, и способы применения
|
WO2014068070A1
(en)
|
2012-10-31 |
2014-05-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for preventing antiphospholipid syndrome (aps)
|
DK2968281T3
(da)
|
2013-03-13 |
2020-11-02 |
Univ Texas |
Mtor-hæmmere til forebyggelse af vækst af tarmpolyp
|
SG11201507093WA
(en)
|
2013-03-14 |
2015-10-29 |
Univ Maryland Baltimore Office Of Technology Transfer |
Androgen receptor down-regulating agents and uses thereof
|
MX2015013894A
(es)
|
2013-04-03 |
2015-12-11 |
Allertein Therapeutics Llc |
Composiciones de nanoparticulas novedosas.
|
CN105636594A
(zh)
|
2013-08-12 |
2016-06-01 |
托凯药业股份有限公司 |
使用雄激素靶向疗法用于治疗肿瘤性疾病的生物标记物
|
US9700544B2
(en)
|
2013-12-31 |
2017-07-11 |
Neal K Vail |
Oral rapamycin nanoparticle preparations
|
CA2968049A1
(en)
|
2014-04-16 |
2015-10-22 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
CN113620978A
(zh)
|
2014-09-11 |
2021-11-09 |
加利福尼亚大学董事会 |
mTORC1抑制剂
|
WO2017029391A1
(en)
|
2015-08-20 |
2017-02-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method for treating cancer
|
WO2018213352A1
(en)
|
2017-05-15 |
2018-11-22 |
C.R. Bard, Inc. |
Medical device with drug-eluting coating and intermediate layer
|
US20200129486A1
(en)
|
2017-06-26 |
2020-04-30 |
Inserm (Institut National De La Santé Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for the treatment of olmsted syndrome
|
WO2019012024A1
(en)
|
2017-07-13 |
2019-01-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS FOR INCREASING EXPANSION AND IMMUNOSUPPRESSIVE CAPACITY OF A CD8 + CD45RCBAS TREGS POPULATION / -
|
AR112834A1
(es)
|
2017-09-26 |
2019-12-18 |
Novartis Ag |
Derivados de rapamicina
|
WO2019212990A1
(en)
|
2018-05-01 |
2019-11-07 |
Revolution Medicines, Inc. |
C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors
|
CN112368289B
(zh)
|
2018-05-01 |
2024-02-20 |
锐新医药公司 |
作为mtor抑制剂的c26-连接的雷帕霉素类似物
|
CN113164557A
(zh)
|
2018-07-23 |
2021-07-23 |
因柯利尔疗法公司 |
治疗神经性病症的方法
|
AU2019310039A1
(en)
|
2018-07-23 |
2021-02-18 |
Enclear Therapies, Inc. |
Methods of treating neurological disorders
|
WO2020053125A1
(en)
|
2018-09-10 |
2020-03-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of neurofibromatosis
|
EP3880266A1
(de)
|
2018-11-14 |
2021-09-22 |
Lutonix, Inc. |
Medizinische vorrichtung mit wirkstofffreisetzender beschichtung auf modifizierter vorrichtungsoberfläche
|
CN113939324A
(zh)
|
2019-04-08 |
2022-01-14 |
巴德外周血管股份有限公司 |
在经改性装置表面上具有药物洗脱涂层的医疗装置
|
WO2020210634A1
(en)
|
2019-04-11 |
2020-10-15 |
Enclear Therapies, Inc. |
Methods of amelioration of cerebrospinal fluid and devices and systems therefor
|
WO2024008799A1
(en)
|
2022-07-06 |
2024-01-11 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of proliferative glomerulonephritis
|
WO2024028433A1
(en)
|
2022-08-04 |
2024-02-08 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of lymphoproliferative disorders
|