DE3220751A1 - Device for crushing concrements, especially renal calculi, in living human or animal bodies - Google Patents

Device for crushing concrements, especially renal calculi, in living human or animal bodies

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Publication number
DE3220751A1
DE3220751A1 DE19823220751 DE3220751A DE3220751A1 DE 3220751 A1 DE3220751 A1 DE 3220751A1 DE 19823220751 DE19823220751 DE 19823220751 DE 3220751 A DE3220751 A DE 3220751A DE 3220751 A1 DE3220751 A1 DE 3220751A1
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shock wave
wave generator
tubular
liquid medium
living human
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DE19823220751
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German (de)
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Jörg Dr. 8022 Grünwald Schüller
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Individual
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Individual
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Priority to DE19823220751 priority Critical patent/DE3220751A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/225—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves
    • A61B17/2251—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves characterised by coupling elements between the apparatus, e.g. shock wave apparatus or locating means, and the patient, e.g. details of bags, pressure control of bag on patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/12—Devices for detecting or locating foreign bodies
    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
    • G10K11/00—Methods or devices for transmitting, conducting or directing sound in general; Methods or devices for protecting against, or for damping, noise or other acoustic waves in general
    • G10K11/004—Mounting transducers, e.g. provided with mechanical moving or orienting device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/371—Surgical systems with images on a monitor during operation with simultaneous use of two cameras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/376—Surgical systems with images on a monitor during operation using X-rays, e.g. fluoroscopy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Acoustics & Sound (AREA)
  • Multimedia (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

A device for crushing concrements, especially renal calculi, in living human or animal bodies has a shock wave generator (4) which generates a focused shock wave (16) in a liquid medium reaching up to the body (1), and at the focal point of this shock wave the concrement (3) can be adjusted, and a container for receiving the liquid medium formed by a tubular or hose-shaped part (7) which adjoins the shock wave generator (4), surrounds the bundle of shock waves (16), can be changed in the longitudinal direction and can be laid against the body (1) with its end facing away from the shock wave generator (4). <IMAGE>

Description

BESCHREIBUNG DESCRIPTION

Die Erfindung betrifft eine Vorrichtung zur Zertrümmerung von Konkrementen, insbesondere von Nierensteinen, im lebenden menschlichen oder tierischen Körper, mit einem Stoßwellengenerator, welcher in einem an den Körper heranreichenden F1.dssigkeitsmedium eine gebündelte Stoßwelle erzeugt, in deren Bündelungspunkt das Konkrement einjustierbar ist, und mit einem Behälter zur Aufnahme des Flüssigkeitsmediums. The invention relates to a device for crushing concrements, in particular of kidney stones in the living human or animal body, with a shock wave generator, which is in a liquid medium reaching the body a bundled shock wave is generated, in whose bundling point the calculus can be adjusted is, and with a container for receiving the liquid medium.

Bei einer bekannten Vorrichtung dieser Art (.Deutsches Arzteblatt - Arztliche Mitteilungen, 78. Jahrgang, Heft 18, Seiten 881 - 886, 30. April 1981) befinden sich Stoßwellengenerator und Patient zusammen in einer wassergefüllten Wanne als Behälter für das FlUssigkeitsmedium. Der Stoßwellengenerator ist ein Hohl-Teilellipsöid, in dessen einem Brennpunkt sich zwischen zwei Elektroden eine Funkenstrecke befindet. Bei Zündung des Funkens kommt es zu einem schlagartigen Verdampfen von Wasser im Bereich der Funkenstrecke, was eine Stoßwelle im Wasser zur Folge hat, die sich zunächst allseitig ausbreitet und durch Reflexion am Ellipsoid auf dessen zweiten Brennpunkt gebündelt wird. In diesen zweiten Brennpunkt wird röntgenkontrolliert das im Patienten vorhandene Konkrement einjustiert, indem der Patient in der Wanne über dem Ellipsoid bewegt wird. Das Vorsehen einer wassergefüllten Wanne, die den Patienten aufnimmt, ist insofern nachteilig, als sie die Vorrichtung platzaufwendig und sperrig macht; Aufgabe der Erfindung ist es daher, eine Vorrichtung der eingangs genannten Art so zu gestalten, daß sie besser handhabbar ist und leichter untergebracht werden kann. In a known device of this type (.Deutsches Arzteblatt - Medical reports, volume 78, issue 18, pages 881 - 886, April 30, 1981) the shock wave generator and patient are together in a water-filled one Tub as a container for the liquid medium. The shock wave generator is a hollow partial ellipsoid, at one focal point there is a spark gap between two electrodes. When the spark ignites, water suddenly evaporates in the Area of the spark gap, which results in a shock wave in the water first spreads out on all sides and by reflection on the ellipsoid on its second Focus is focused. X-ray control is carried out in this second focal point adjusts the calculus present in the patient by placing the patient in the tub is moved over the ellipsoid. The provision of a water-filled tub that the Receiving patients is disadvantageous in that the device takes up a lot of space and bulky; The object of the invention is therefore to provide a device of the initially mentioned called type so that it is easier to handle and accommodated more easily can be.

Diese Aufgabe wird erfindungsgemäß dadurch gelöst, daß der Behälter zur Aufnahme des Flüssigkeitsmediums durch ein an den Stoßwellengenerator anschließendes, das Stoßwellenbündel umgebendes schlauchförmiges Teil gebildet ist, welches mit seinem dem Stoßwellengenerator abgekehrten Ende an den Körper anschmiegbar ist. Auf diese Weise wird das Behältervolumen auf das für die ungestörte Ausbreitung der Stoßwelle notwendige Volumen- reduziert, so daß die Gesamtvorrichtung durch das Entfallen einer der Körpergröße eines Menschen angepaßte Wanne wesentlich kleiner gehalten werden kann. Im Gebrauch wird das rohr- bzw. schlauchförmige Teil mit seinem dem Stoßwellengenerator abgeke.hrten Ende an den Körper des Patienten angelegt, wobei über die Längsveränderlichkeit des Teils sichergestellt ist, daß das zu zertrümmernde Konkrement in den Bündelungspunkt der Stoßwelle einjustiert werden kann. This object is achieved according to the invention in that the container for taking up the liquid medium through a connected to the shock wave generator, the tubular part surrounding the shock wave bundle is formed, which with its end facing away from the shock wave generator can be snuggled to the body. In this way, the container volume is sufficient for undisturbed spreading the necessary volume- reduced so that the entire device through the omission of a tub adapted to the body size of a person is much smaller can be held. In use, the tubular or hose-shaped part is with his the end turned away from the shock wave generator is placed on the patient's body, whereby the longitudinal variability of the part ensures that the part to be smashed Concrement can be adjusted into the bundling point of the shock wave.

Gemäß einer vorteilhaften Ausgestaltung der Erfindung ist das dem Stoßwellengenerator abgekehrte Ende des rohr-bzw. schlauchförmigen Teils durch eine an den Körper des Patienten anschmiegbare Membran abgeschlossen. Diese Membran hat zweckmäßigerweise gleiche Scha]lwiderstandseigenschaften wie Wasser bzw. Körpergewebe, so daß an ihr weitgehend keine Reflexionen auftreten. Bei einer solchen Anordnung kann das rotlr- bzw. schlauchförmige Teil dauernd mit Wasser gefüllt zein, wobei etwa ein Ausgleichsgefäß vorgesehen sein kann, das dasjenige Wasser aufnimmt bzw. According to an advantageous embodiment of the invention, this is the Shock wave generator facing away from the end of the tube or. tubular part by a Completed membrane that can be snuggled to the patient's body. This membrane has expediently the same shell resistance properties as water or body tissue, so that largely no reflections occur on it. With such an arrangement the red or tubular part can be filled with water continuously, whereby for example, a compensation tank can be provided that absorbs or absorbs that water.

abgibt, das je nach Justierrichtung im rohr- bzw. schlauchförmigen Teil zuviel oder zuwenig vorhanden ist.releases, depending on the direction of adjustment in the tubular or hose-shaped Part is too much or too little.

Nach einer weiteren bevorzugten Ausgestaltung der Erfindung ist das rohr- bzw. schlauchförmige Teil an seinem dom Stoßwellengenerator.abgekehrten Ende offen und eine Einrichtung zur Erzeugung eines das dem Stoßwellengenerator abgekehrte Ende an clen Körper ansaugenden Unterdruckes in dem rohr- bzw. schl.luchförmigen Teil vorgesehen. Auf diese Weise soll bei direkter Berührung von Wasser und Patient ein einen Wasseraustritt verhinclernder dichtender Anschluß des Teils am Körper dtws Patienten erreicht werden. According to a further preferred embodiment of the invention, this is tubular or hose-shaped part at its dome shock wave generator, turned away end open and a device for generating one that faces away from the shock wave generator The end of the negative pressure sucking into the body in the tubular or tube-shaped Part provided. In this way, the patient is supposed to be in direct contact with the water a sealing connection of the part to the body which prevents water from escaping dtws patients can be reached.

Eine AusEühunl]sform der lert.-induna wird im folgenden anhand der einzigen Figur der beiqefücjten Zeichnung beschrieben, welche die Vorrichtung in stark schematisieren- der Darstellung zeigt. A form of the lert.-induna is given in the following the single figure of the attached drawing, which shows the device in strongly schematize the illustration shows.

Bei 1 ist ein menschlicher Körper im Schnitt, bei 2 jeweils eine Niere und bei 3 ein Nierenstein angedeutet. At 1, a human body is on average, at 2, one at a time Kidney and at 3 a kidney stone indicated.

Ein Stoßwellengenerator 4 umfaßt ein hohlförmiges Teilellipsoid 5 als Reflektor und eine in dem einen Brennpunkt des Ellipsoids angeordnete Funkenstrecke 6. Am offenen Ende des Teilellipsoids 5 ist, dieses umgebend, ein rohrförmiges Teil 7 angeschlossen, das an seinem dem Ellipsoid abgekehrten Ende mit einer hinsichtlich ihrer Schallwiderstandseigenschaften dem Wasser bzw. menschlichen Gewebe angepaßten Membran 8 abgeschlossen ist, die sich beim Andrücken gegen den-menschlichen Körper an diesen anschmiegt, Das rohrförmige Teil ist so dimensioniert, daß keine Beeinflussung des fokussierten Stoßwellenbündels 16 durch seine Wände erfolgt.A shock wave generator 4 comprises a hollow part ellipsoid 5 as a reflector and a spark gap arranged in one focal point of the ellipsoid 6. At the open end of the partial ellipsoid 5, surrounding it, is a tubular part 7 connected, which at its end remote from the ellipsoid with a respect their sound resistance properties adapted to the water or human tissue Membrane 8 is complete, which is when pressed against the human body clings to this, the tubular part is dimensioned so that no interference of the focused shock wave bundle 16 takes place through its walls.

Das von der Membran 8 und dem Stoßwellengenerator 4 an seinen Enden abgeschlossene rohrförmige Teil 7 ist mit Wasser gefüllt. Das rohrförmige Teil 7 ist im vorliegenden Beispiel als elastischer Balg ausgebildet, der eine Verschiebung des Körpers des Patienten zum und vom Stoßwellengenerator 4 gestattet, ohne daß die Membran 8 von der Körperoberfläche abhebt. Der Stoßwellengenerator 4-wird unter Röntgenkontrolle durch Bewegen des Patienten in der Achse des Stoßwellengenerators und senkrecht dazu solange einjustiert, bis der zu zerstörende Nierenstein im zweiten Brennpunkt des Ellipsoids liegt. Hierzu sind in bekannter Weise zwei Röntgengeräte 8, 9 vorgesehen, deren Bilder über Bildverstärker 10 und 11 auf Monitoren 12 und 13 beobachtet werden, auf denen die Sollage für den Nierenstein mit Fadenkreuzen markiert ist. Ebenso ist eine Ortung mit hochauflösenden fernfokussierten Ultraschallsonden möglich.That of the membrane 8 and the shock wave generator 4 at its ends closed tubular part 7 is filled with water. The tubular part 7 is designed in the present example as an elastic bellows that allows a displacement of the patient's body to and from the shock wave generator 4 allowed without the membrane 8 lifts from the body surface. The shock wave generator 4 is under X-ray control by moving the patient in the axis of the shock wave generator and adjusted perpendicular to it until the kidney stone to be destroyed is in the second Focal point of the ellipsoid. Two X-ray devices are used for this in a known manner 8, 9 provided, the images of which via image intensifiers 10 and 11 on monitors 12 and 13 can be observed, on which the target position for the kidney stone with crosshairs is marked. Localization with high-resolution, remote-focused ultrasonic probes is also possible possible.

Die Füllung des beiderseits abgeschlossenen rohrförmigen Teils 7 mit Wasser kann über einen bei 14. angedeuteten Einlaß erfolgen, wobei man sich etwa vorstellen kann, daß dieser kommunizierend mit einem Gefäß in Verbindung steht, in dlls überschüssiges Wasser zurückgedrückt wird, wenn der St<#ßwellengenerator 4 im Zuge der Justierung näher an die Kdrperoberfläche herangerückt wird. In Verlängerung der Achse des auf den zu zertrümmernden Nierenstein 3 fokussierten Bündels ist auf der Körperoberfläche des Patienten ein mit Wasser.gefülltes Kissen 15 vorgesehen, das Reflexionen der Stoßwellenreste beim Austritt aus dem Körper verhindern soll. The filling of the tubular part 7 closed on both sides with water can be done via an inlet indicated at 14, whereby one can imagine that this is communicating with a vessel, in dlls excess water is pushed back when the St <# ßwellegenerator 4 in the course of the adjustment moved to the surface of the body will. As an extension of the axis of the one focused on the kidney stone 3 to be smashed Bundle is a pillow filled with water on the patient's body surface 15 provided, the reflections of the shock wave residues when exiting the body should prevent.

Mit dieser Anordnung ist die viel Platz einnehmende Wanne vermieden, wobei gleichzeitig dem Patienten die Unbequemlichkeit eines Wasserbades erspart wird. Außerdem erübrigt sich eine aufwändige Unterwasserröntgentechnik. With this arrangement, the tub, which takes up a lot of space, is avoided. while at the same time saves the patient the inconvenience of a water bath will. In addition, there is no need for complex underwater X-ray technology.

Die federbalgartige Ausbildung des rohrförmigen Teils ist nur als Beispiel zu verstehen, andere Ausbildungen, etwa eine teleskopartige, die Abstandsveränderungen zwischen dem Stoßwellengenerator 4 und der Körperoberfläche des Patienten zulassen, sind ebenfalls möglich. The bellows-like design of the tubular part is only as To understand example, other trainings, such as a telescopic one, the changes in distance allow between the shock wave generator 4 and the patient's body surface, are also possible.

Bei patientenseitig offener Ausbildung des rohr- bzw. If the tube or tube is open on the patient side.

schlauchförmigen Teils (7) wird in diesem ein Unterdruck erzeugt, durch den das offene Ende gegen den Körper des Patienten angesaugt wird. Hierbei ist eine lippenförmige Ausbildung des offenen Endes besonders vorteilhaft.tubular part (7) a negative pressure is generated in this, through which the open end is sucked against the patient's body. Here a lip-shaped design of the open end is particularly advantageous.

Anstelle mit einem Unterdruck zu arbeiten, kann das offene Ende des rohr- bzw. schlauchförmigen Teils auch mit Hilfe von um den Körper des Patienten gelegten Riemen am Körper festgelegt werden. Instead of working with a vacuum, the open end of the tubular or hose-shaped part also with the help of around the patient's body straps are attached to the body.

Claims (3)

Vorrichtung zur Zertrümmerung von Konkrementen, insbe-sondere von Nierensteinen, im lebenden menschlichen oder tierischen Körper PATENTAN-SPRUCHE Vorrichtung zur Zertrümmeruny von Konkrementen, insbesondere von Nierensteinen, im lebenden menschlichen oder tierischen Körper, mit einem Stoßwellengenerator, welcher in einem an den Körper heranreichenden Flüssigkeitsmedium eine qebündelte Stoßwelle erzeugt, in deren Bündeiungspunkt das Konkrement einjustierbar ist, und mit einem Behälter zur Aufnahme des Flüssigkeitsmediums, dadurch g e k e n n z e i c h n e t , daß der Behälter zur AufnaIim< dc#s Flüssigkeitsmediums durch ein an den S#oßwellengenerator (4) anschließendes, das Stoßwellenbündel (16) umgebendes längsveränderliches rohr- bzw. schlauchförmiges Teil (7) gebildet ist, welches mit seinem dem Stoßwelleng.'nerator (4) abgekehrten Ende an den Körper (.13 anschmiegbar ist.Device for crushing concretions, in particular from Kidney stones, in the living human or animal body Device for smashing concretions, in particular kidney stones, in the living human or animal body, with a shock wave generator, which bundled one in a liquid medium reaching the body Shock wave generated, in the bundling point of which the calculus can be adjusted, and with a container for receiving the liquid medium, thereby g e n n z e i c h n e t that the container for receiving <dc # s liquid medium through a adjoining the shock wave generator (4) and surrounding the shock wave bundle (16) longitudinally variable tubular or hose-shaped part (7) is formed, which with its end facing away from the shock wave generator (4) clings to the body (.13 is. 2. Vorrichtung nach Anspruch 1, dadurch g e -k e n n z e i c h n e t , daß das dem Stoßwellengenerator (4) abgekehrte Ende des rohr- bzw. schlauchförmigen Teils (7) durch eine an den Körper (1) anschmiegbare Membran (8) abgeschlossen ist. 2. Apparatus according to claim 1, characterized in that g e -k e n n z e i c h n e t that the shock wave generator (4) facing away from the end of the tubular or hose-shaped Part (7) is closed off by a membrane (8) which can be fitted to the body (1). 3. Vorrichtung nach Anspruch 1, dadurch g e -k e n n z e i c h n e t , daß das rohr- bzw. schlauchförmige Teil (7) an seinem dem Stoßwellengenerator (4) abgekehrten Ende offen ist und daß eine Einrichtung zur Erzeugung eines das dem Stoßwellengenerator (4) abgekehrte Ende an den Körper ansaugenden Unterdrucks in dem rohr-bzw. schlauchförmigen Teil (7) vorgesehen ist. 3. Apparatus according to claim 1, characterized in that g e -k e n n z e i c h n e t that the tubular or hose-shaped part (7) on its the shock wave generator (4) the remote end is open and that a device for generating a das the end facing away from the shock wave generator (4) to the body sucking negative pressure in the pipe or. tubular part (7) is provided.
DE19823220751 1982-06-02 1982-06-02 Device for crushing concrements, especially renal calculi, in living human or animal bodies Withdrawn DE3220751A1 (en)

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WO1985003631A1 (en) * 1984-02-22 1985-08-29 Washington Research Foundation Apparatus for the noninvasive shock fragmentation of renal calculi
EP0166102A1 (en) * 1984-05-15 1986-01-02 DORNIER SYSTEM GmbH Device for the nontactile disintegration of concrements with coaxial detection
EP0168559A1 (en) * 1984-07-18 1986-01-22 DORNIER SYSTEM GmbH Device for detecting and positioning concrements
EP0169311A1 (en) * 1984-07-21 1986-01-29 Dornier Gmbh Device for detecting and positioning
EP0170416A1 (en) * 1984-06-30 1986-02-05 Kabushiki Kaisha Toshiba Ultrasound hyperthermia apparatus
EP0206331A2 (en) * 1985-06-26 1986-12-30 Yachiyoda Sangyo Co., Ltd. Apparatus for disintegrating calculus by underwater shock wave from outside human body
EP0205878A1 (en) * 1985-05-28 1986-12-30 Siemens Aktiengesellschaft Apparatus for the contactless disintegration of concrements
DE3617032A1 (en) * 1985-05-24 1987-01-08 Elscint Ltd Ultrasonic apparatus for locating stone formations
EP0211680A1 (en) * 1985-08-12 1987-02-25 The Special Trustees for St. Thomas' Hospital Method of calibrating a kidney lithotripter
FR2587194A1 (en) * 1985-09-13 1987-03-20 Wolf Gmbh Richard DEVICE FOR LOCALIZING AND DESTROYING CONCRETIONS IN BODY CAVITIES
DE3536073A1 (en) * 1985-10-09 1987-04-09 Siemens Ag Device for crushing calculi
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DE3543867A1 (en) * 1985-12-12 1987-06-25 Wolf Gmbh Richard DEVICE FOR SPACIOUS LOCATION AND DESTRUCTION OF CONCRETE IN BODY CAVES
WO1987003797A1 (en) * 1985-12-17 1987-07-02 Wolfgang Eisenmenger Installation for the acoustical and mechanical coupling of pressure waves, especially focussed shock waves on the body of living beings
EP0229981A1 (en) * 1985-12-20 1987-07-29 Siemens Aktiengesellschaft Method for controlling the focussing characteristics of an ultrasonic field and device for carrying out said method
DE3608877A1 (en) * 1986-03-17 1987-09-24 Non Invasive Therapeutic Tech DEVICE FOR CRUSHING KIDNEY STONES BY MEANS OF SHOCK WAVES
EP0238772A1 (en) * 1985-09-09 1987-09-30 Moshe Ein-Gal Apparatus for the disintegration of body calculi
EP0248323A1 (en) * 1986-06-05 1987-12-09 Siemens Aktiengesellschaft Locating X-ray device
EP0256436A1 (en) * 1986-08-18 1988-02-24 Siemens Aktiengesellschaft Concretion smashing device
FR2605874A1 (en) * 1986-10-29 1988-05-06 Univ Karlova DEVICE FOR THE CLINICAL EXECUTION OF EXTRA-BODILY LITHOTRIPSY
DE3638953A1 (en) * 1986-11-14 1988-05-26 Dornier Medizintechnik COMPUTER CONTROLLED PATIENT POSITIONING
US4798196A (en) * 1986-12-16 1989-01-17 Trutek Research, Inc. Shroud for coupling kidney stone disintegrator to human body
US4811725A (en) * 1986-12-22 1989-03-14 Siemens Aktiengesellschaft Extracorporeal lithotripsy apparatus
US4813415A (en) * 1986-08-18 1989-03-21 Siemens Aktiengesellschaft Sensor for evaluation of shock wave pulses
US4829986A (en) * 1986-08-22 1989-05-16 Siemens Aktiengesellschaft Lithotripsy work station
DE3835318C1 (en) * 1988-10-17 1990-06-28 Storz Medical Ag, Kreuzlingen, Ch
US4991604A (en) * 1988-04-09 1991-02-12 Richard Wolf Gmbh Ultrasonic treatment apparatus
USRE33590E (en) 1983-12-14 1991-05-21 Edap International, S.A. Method for examining, localizing and treating with ultrasound
DE4005228A1 (en) * 1990-02-20 1991-08-22 Wolf Gmbh Richard LITHOTRIPSY DEVICE WITH A PLANT FOR TREATING THE ACOUSTIC COUPLING MEDIUM
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DE19521475A1 (en) * 1995-06-13 1996-12-19 Dornier Medizintechnik Sound or shock wave induction device
DE19532219A1 (en) * 1995-09-01 1997-04-03 Tzn Forschung & Entwicklung Energy converter for high-performance pulse generation
DE19649738A1 (en) * 1996-11-30 1998-06-04 Dornier Medizintechnik High capacity pressure wave source for producing short bursts of high- energy pressure waves
DE19929112A1 (en) * 1999-06-24 2001-01-11 Ferton Holding Sa Medical instrument for the treatment of biological tissue and method for transmitting pressure waves
WO2005075020A1 (en) * 2004-02-02 2005-08-18 Sanuwave, Inc. Use of an extracorporal shock wave applicator
US7985189B1 (en) 1996-03-29 2011-07-26 Sanuwave, Inc. Method for using acoustic shock waves in the treatment of medical conditions
US9049783B2 (en) 2012-04-13 2015-06-02 Histosonics, Inc. Systems and methods for obtaining large creepage isolation on printed circuit boards
US9061131B2 (en) 2009-08-17 2015-06-23 Histosonics, Inc. Disposable acoustic coupling medium container
US9144694B2 (en) 2011-08-10 2015-09-29 The Regents Of The University Of Michigan Lesion generation through bone using histotripsy therapy without aberration correction
US9636133B2 (en) 2012-04-30 2017-05-02 The Regents Of The University Of Michigan Method of manufacturing an ultrasound system
US9642634B2 (en) 2005-09-22 2017-05-09 The Regents Of The University Of Michigan Pulsed cavitational ultrasound therapy
US9901753B2 (en) 2009-08-26 2018-02-27 The Regents Of The University Of Michigan Ultrasound lithotripsy and histotripsy for using controlled bubble cloud cavitation in fractionating urinary stones
US9943708B2 (en) 2009-08-26 2018-04-17 Histosonics, Inc. Automated control of micromanipulator arm for histotripsy prostate therapy while imaging via ultrasound transducers in real time
US10219815B2 (en) 2005-09-22 2019-03-05 The Regents Of The University Of Michigan Histotripsy for thrombolysis
US10293187B2 (en) 2013-07-03 2019-05-21 Histosonics, Inc. Histotripsy excitation sequences optimized for bubble cloud formation using shock scattering
US10780298B2 (en) 2013-08-22 2020-09-22 The Regents Of The University Of Michigan Histotripsy using very short monopolar ultrasound pulses
US11058399B2 (en) 2012-10-05 2021-07-13 The Regents Of The University Of Michigan Bubble-induced color doppler feedback during histotripsy
US11135454B2 (en) 2015-06-24 2021-10-05 The Regents Of The University Of Michigan Histotripsy therapy systems and methods for the treatment of brain tissue
US11432900B2 (en) 2013-07-03 2022-09-06 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
US11648424B2 (en) 2018-11-28 2023-05-16 Histosonics Inc. Histotripsy systems and methods
US11813485B2 (en) 2020-01-28 2023-11-14 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization
US11953471B2 (en) 2020-12-15 2024-04-09 The Boeing Company Under water acoustics plasma generator

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EP0166102A1 (en) * 1984-05-15 1986-01-02 DORNIER SYSTEM GmbH Device for the nontactile disintegration of concrements with coaxial detection
EP0170416A1 (en) * 1984-06-30 1986-02-05 Kabushiki Kaisha Toshiba Ultrasound hyperthermia apparatus
EP0168559A1 (en) * 1984-07-18 1986-01-22 DORNIER SYSTEM GmbH Device for detecting and positioning concrements
DE3426398C1 (en) * 1984-07-18 1987-11-12 Dornier System Gmbh, 7990 Friedrichshafen Device for spatial location and positioning of calculus
EP0169311A1 (en) * 1984-07-21 1986-01-29 Dornier Gmbh Device for detecting and positioning
DE3427001C1 (en) * 1984-07-21 1986-02-06 Dornier System Gmbh, 7990 Friedrichshafen Locating and positioning device
DE3617032A1 (en) * 1985-05-24 1987-01-08 Elscint Ltd Ultrasonic apparatus for locating stone formations
EP0205878A1 (en) * 1985-05-28 1986-12-30 Siemens Aktiengesellschaft Apparatus for the contactless disintegration of concrements
US4877017A (en) * 1985-05-28 1989-10-31 Siemens Aktiengesellschaft Apparatus for non-contacting disintegration of concretions
EP0206331A3 (en) * 1985-06-26 1988-12-14 Yachiyoda Sangyo Co., Ltd. Apparatus for disintegrating calculus by underwater shock wave from outside human body
US4893614A (en) * 1985-06-26 1990-01-16 Yachiyoda Sangyo Co. Ltd. Apparatus for disintegrating a calculus by an underwater shock wave from outside the human body
EP0206331A2 (en) * 1985-06-26 1986-12-30 Yachiyoda Sangyo Co., Ltd. Apparatus for disintegrating calculus by underwater shock wave from outside human body
EP0211680A1 (en) * 1985-08-12 1987-02-25 The Special Trustees for St. Thomas' Hospital Method of calibrating a kidney lithotripter
EP0238772A1 (en) * 1985-09-09 1987-09-30 Moshe Ein-Gal Apparatus for the disintegration of body calculi
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US4869239A (en) * 1985-09-13 1989-09-26 Richard Wolf Gmbh Device for locating and disintegrating concretions in bodily cavities
DE3532678A1 (en) * 1985-09-13 1987-03-26 Wolf Gmbh Richard DEVICE FOR LOCATING AND CRUSHING CONCRETE IN BODY CAVES
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US4796613A (en) * 1985-10-09 1989-01-10 Siemens Aktiengesellschaft Lithotripsy work station
EP0221325A1 (en) 1985-10-09 1987-05-13 Siemens Aktiengesellschaft Lithotripsy unit
DE3536073A1 (en) * 1985-10-09 1987-04-09 Siemens Ag Device for crushing calculi
DE3543867A1 (en) * 1985-12-12 1987-06-25 Wolf Gmbh Richard DEVICE FOR SPACIOUS LOCATION AND DESTRUCTION OF CONCRETE IN BODY CAVES
US4771787A (en) * 1985-12-12 1988-09-20 Richard Wolf Gmbh Ultrasonic scanner and shock wave generator
US4821730A (en) * 1985-12-12 1989-04-18 Richard Wolf Gmbh Ultrasonic scanner and shock wave generator
WO1987003797A1 (en) * 1985-12-17 1987-07-02 Wolfgang Eisenmenger Installation for the acoustical and mechanical coupling of pressure waves, especially focussed shock waves on the body of living beings
US4725989A (en) * 1985-12-20 1988-02-16 Siemens Aktiengesellschaft Method controlling the focusing of an ultrasonic field and apparatus for performing said method
EP0229981A1 (en) * 1985-12-20 1987-07-29 Siemens Aktiengesellschaft Method for controlling the focussing characteristics of an ultrasonic field and device for carrying out said method
DE3608877A1 (en) * 1986-03-17 1987-09-24 Non Invasive Therapeutic Tech DEVICE FOR CRUSHING KIDNEY STONES BY MEANS OF SHOCK WAVES
EP0248323A1 (en) * 1986-06-05 1987-12-09 Siemens Aktiengesellschaft Locating X-ray device
US4761803A (en) * 1986-06-05 1988-08-02 Siemens Aktiengesellschaft X-ray diagnostics installation
US4813415A (en) * 1986-08-18 1989-03-21 Siemens Aktiengesellschaft Sensor for evaluation of shock wave pulses
EP0256436A1 (en) * 1986-08-18 1988-02-24 Siemens Aktiengesellschaft Concretion smashing device
US4829986A (en) * 1986-08-22 1989-05-16 Siemens Aktiengesellschaft Lithotripsy work station
FR2605874A1 (en) * 1986-10-29 1988-05-06 Univ Karlova DEVICE FOR THE CLINICAL EXECUTION OF EXTRA-BODILY LITHOTRIPSY
EP0269801A1 (en) * 1986-11-14 1988-06-08 Dornier Medizintechnik Gmbh Positioning of a patient by a controlled computer
DE3638953A1 (en) * 1986-11-14 1988-05-26 Dornier Medizintechnik COMPUTER CONTROLLED PATIENT POSITIONING
US4798196A (en) * 1986-12-16 1989-01-17 Trutek Research, Inc. Shroud for coupling kidney stone disintegrator to human body
US4811725A (en) * 1986-12-22 1989-03-14 Siemens Aktiengesellschaft Extracorporeal lithotripsy apparatus
US4991604A (en) * 1988-04-09 1991-02-12 Richard Wolf Gmbh Ultrasonic treatment apparatus
DE3835318C1 (en) * 1988-10-17 1990-06-28 Storz Medical Ag, Kreuzlingen, Ch
US5113848A (en) * 1989-10-02 1992-05-19 Richard Wolf Gmbh Apparatus for shock wave therapy
DE4005228A1 (en) * 1990-02-20 1991-08-22 Wolf Gmbh Richard LITHOTRIPSY DEVICE WITH A PLANT FOR TREATING THE ACOUSTIC COUPLING MEDIUM
US5195509A (en) * 1990-02-20 1993-03-23 Richard Wolf Gmbh Disinfectant system for a lithotripsy apparatus
DE19513400A1 (en) * 1995-04-08 1996-10-10 Dornier Medizintechnik Device for locating concrements in bodies of living beings
DE19521475A1 (en) * 1995-06-13 1996-12-19 Dornier Medizintechnik Sound or shock wave induction device
DE19532219A1 (en) * 1995-09-01 1997-04-03 Tzn Forschung & Entwicklung Energy converter for high-performance pulse generation
US7985189B1 (en) 1996-03-29 2011-07-26 Sanuwave, Inc. Method for using acoustic shock waves in the treatment of medical conditions
DE19649738C2 (en) * 1996-11-30 1998-09-24 Dornier Medizintechnik High performance pressure wave source
DE19649738A1 (en) * 1996-11-30 1998-06-04 Dornier Medizintechnik High capacity pressure wave source for producing short bursts of high- energy pressure waves
DE19929112A1 (en) * 1999-06-24 2001-01-11 Ferton Holding Sa Medical instrument for the treatment of biological tissue and method for transmitting pressure waves
WO2005075020A1 (en) * 2004-02-02 2005-08-18 Sanuwave, Inc. Use of an extracorporal shock wave applicator
US11701134B2 (en) 2005-09-22 2023-07-18 The Regents Of The University Of Michigan Histotripsy for thrombolysis
US11364042B2 (en) 2005-09-22 2022-06-21 The Regents Of The University Of Michigan Histotripsy for thrombolysis
US10219815B2 (en) 2005-09-22 2019-03-05 The Regents Of The University Of Michigan Histotripsy for thrombolysis
US9642634B2 (en) 2005-09-22 2017-05-09 The Regents Of The University Of Michigan Pulsed cavitational ultrasound therapy
EP2467062B1 (en) * 2009-08-17 2017-01-18 Histosonics, Inc. Disposable acoustic coupling medium container
US9526923B2 (en) 2009-08-17 2016-12-27 Histosonics, Inc. Disposable acoustic coupling medium container
US9061131B2 (en) 2009-08-17 2015-06-23 Histosonics, Inc. Disposable acoustic coupling medium container
US9901753B2 (en) 2009-08-26 2018-02-27 The Regents Of The University Of Michigan Ultrasound lithotripsy and histotripsy for using controlled bubble cloud cavitation in fractionating urinary stones
US9943708B2 (en) 2009-08-26 2018-04-17 Histosonics, Inc. Automated control of micromanipulator arm for histotripsy prostate therapy while imaging via ultrasound transducers in real time
US10071266B2 (en) 2011-08-10 2018-09-11 The Regents Of The University Of Michigan Lesion generation through bone using histotripsy therapy without aberration correction
US9144694B2 (en) 2011-08-10 2015-09-29 The Regents Of The University Of Michigan Lesion generation through bone using histotripsy therapy without aberration correction
US9049783B2 (en) 2012-04-13 2015-06-02 Histosonics, Inc. Systems and methods for obtaining large creepage isolation on printed circuit boards
US9636133B2 (en) 2012-04-30 2017-05-02 The Regents Of The University Of Michigan Method of manufacturing an ultrasound system
US11058399B2 (en) 2012-10-05 2021-07-13 The Regents Of The University Of Michigan Bubble-induced color doppler feedback during histotripsy
US11432900B2 (en) 2013-07-03 2022-09-06 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
US10293187B2 (en) 2013-07-03 2019-05-21 Histosonics, Inc. Histotripsy excitation sequences optimized for bubble cloud formation using shock scattering
US10780298B2 (en) 2013-08-22 2020-09-22 The Regents Of The University Of Michigan Histotripsy using very short monopolar ultrasound pulses
US11819712B2 (en) 2013-08-22 2023-11-21 The Regents Of The University Of Michigan Histotripsy using very short ultrasound pulses
US11135454B2 (en) 2015-06-24 2021-10-05 The Regents Of The University Of Michigan Histotripsy therapy systems and methods for the treatment of brain tissue
US11648424B2 (en) 2018-11-28 2023-05-16 Histosonics Inc. Histotripsy systems and methods
US11813484B2 (en) 2018-11-28 2023-11-14 Histosonics, Inc. Histotripsy systems and methods
US11813485B2 (en) 2020-01-28 2023-11-14 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization
US11953471B2 (en) 2020-12-15 2024-04-09 The Boeing Company Under water acoustics plasma generator

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