DE3269474D1 - Thiazole derivatives and their use in the manufacture of beta-lactam antibiotics - Google Patents

Thiazole derivatives and their use in the manufacture of beta-lactam antibiotics

Info

Publication number
DE3269474D1
DE3269474D1 DE8282306043T DE3269474T DE3269474D1 DE 3269474 D1 DE3269474 D1 DE 3269474D1 DE 8282306043 T DE8282306043 T DE 8282306043T DE 3269474 T DE3269474 T DE 3269474T DE 3269474 D1 DE3269474 D1 DE 3269474D1
Authority
DE
Germany
Prior art keywords
beta
lactam antibiotics
manufacture
thiazole derivatives
triphenylmethylaminothiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282306043T
Other languages
English (en)
Inventor
William Sutherland Strachan
Alastair Couper Brodie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE3269474D1 publication Critical patent/DE3269474D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE8282306043T 1981-11-13 1982-11-12 Thiazole derivatives and their use in the manufacture of beta-lactam antibiotics Expired DE3269474D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8134359 1981-11-13

Publications (1)

Publication Number Publication Date
DE3269474D1 true DE3269474D1 (en) 1986-04-03

Family

ID=10525889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282306043T Expired DE3269474D1 (en) 1981-11-13 1982-11-12 Thiazole derivatives and their use in the manufacture of beta-lactam antibiotics

Country Status (5)

Country Link
US (2) US4510312A (de)
EP (1) EP0088847B1 (de)
JP (1) JPS58135872A (de)
AT (1) ATE18219T1 (de)
DE (1) DE3269474D1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE18219T1 (de) * 1981-11-13 1986-03-15 Glaxo Group Ltd Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika.
US4426528A (en) * 1982-04-01 1984-01-17 Eli Lilly And Company Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid
CN103804395B (zh) * 2014-01-16 2015-12-02 天津大学 头孢噻肟钠n,n-二甲基甲酰胺溶剂化合物及制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
ATE18219T1 (de) * 1981-11-13 1986-03-15 Glaxo Group Ltd Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika.

Also Published As

Publication number Publication date
US4510312A (en) 1985-04-09
JPS58135872A (ja) 1983-08-12
US4670552A (en) 1987-06-02
ATE18219T1 (de) 1986-03-15
EP0088847B1 (de) 1986-02-26
JPH0354661B2 (de) 1991-08-20
EP0088847A1 (de) 1983-09-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee