DE3665592D1 - Supports, the preparation of these supports, intermediates obtained, their use in the synthesis of oligonucleotides, and nucleosides and oligonucleotides linked to the supports - Google Patents
Supports, the preparation of these supports, intermediates obtained, their use in the synthesis of oligonucleotides, and nucleosides and oligonucleotides linked to the supportsInfo
- Publication number
- DE3665592D1 DE3665592D1 DE8686401289T DE3665592T DE3665592D1 DE 3665592 D1 DE3665592 D1 DE 3665592D1 DE 8686401289 T DE8686401289 T DE 8686401289T DE 3665592 T DE3665592 T DE 3665592T DE 3665592 D1 DE3665592 D1 DE 3665592D1
- Authority
- DE
- Germany
- Prior art keywords
- supports
- oligonucleotides
- nucleosides
- synthesis
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8509382A FR2583772B1 (fr) | 1985-06-20 | 1985-06-20 | Nouveaux supports, la preparation de ces supports, les intermediaires nouveaux obtenus, leur application a la synthese d'oligonucleotides et les nouveaux nucleosides et oligonucleotides relies aux supports ainsi obtenus |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3665592D1 true DE3665592D1 (en) | 1989-10-19 |
Family
ID=9320468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686401289T Expired DE3665592D1 (en) | 1985-06-20 | 1986-06-13 | Supports, the preparation of these supports, intermediates obtained, their use in the synthesis of oligonucleotides, and nucleosides and oligonucleotides linked to the supports |
Country Status (6)
Country | Link |
---|---|
US (1) | US4780504A (de) |
EP (1) | EP0206913B1 (de) |
JP (1) | JPS61293553A (de) |
CA (1) | CA1265756A (de) |
DE (1) | DE3665592D1 (de) |
FR (1) | FR2583772B1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2619568B1 (fr) * | 1987-08-21 | 1989-07-07 | Centre Nat Rech Scient | Polymeres derives du polystyrene, leurs procedes de preparation et leurs applications pour l'analyse et la purification de molecules d'origine biologique |
US6551784B2 (en) | 1989-06-07 | 2003-04-22 | Affymetrix Inc | Method of comparing nucleic acid sequences |
US6309822B1 (en) | 1989-06-07 | 2001-10-30 | Affymetrix, Inc. | Method for comparing copy number of nucleic acid sequences |
US6919211B1 (en) | 1989-06-07 | 2005-07-19 | Affymetrix, Inc. | Polypeptide arrays |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US6346413B1 (en) | 1989-06-07 | 2002-02-12 | Affymetrix, Inc. | Polymer arrays |
US6955915B2 (en) | 1989-06-07 | 2005-10-18 | Affymetrix, Inc. | Apparatus comprising polymers |
US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
US6406844B1 (en) | 1989-06-07 | 2002-06-18 | Affymetrix, Inc. | Very large scale immobilized polymer synthesis |
US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
US6416952B1 (en) | 1989-06-07 | 2002-07-09 | Affymetrix, Inc. | Photolithographic and other means for manufacturing arrays |
US6506558B1 (en) | 1990-03-07 | 2003-01-14 | Affymetrix Inc. | Very large scale immobilized polymer synthesis |
EP0834576B1 (de) | 1990-12-06 | 2002-01-16 | Affymetrix, Inc. (a Delaware Corporation) | Detektion von Nukleinsäuresequenzen |
US6468740B1 (en) | 1992-11-05 | 2002-10-22 | Affymetrix, Inc. | Cyclic and substituted immobilized molecular synthesis |
US6287850B1 (en) * | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
US6121048A (en) * | 1994-10-18 | 2000-09-19 | Zaffaroni; Alejandro C. | Method of conducting a plurality of reactions |
US8236493B2 (en) | 1994-10-21 | 2012-08-07 | Affymetrix, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA |
US6720149B1 (en) * | 1995-06-07 | 2004-04-13 | Affymetrix, Inc. | Methods for concurrently processing multiple biological chip assays |
EP0880598A4 (de) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | Verfahren zur analyse von nukleinsäure |
US6146833A (en) * | 1997-02-11 | 2000-11-14 | Beckman Coulter, Inc. | Polymeric reagents for immobilizing biopolymers |
US6545264B1 (en) | 1998-10-30 | 2003-04-08 | Affymetrix, Inc. | Systems and methods for high performance scanning |
US7612020B2 (en) | 1998-12-28 | 2009-11-03 | Illumina, Inc. | Composite arrays utilizing microspheres with a hybridization chamber |
US6455007B1 (en) * | 2000-06-13 | 2002-09-24 | Symyx Technologies, Inc. | Apparatus and method for testing compositions in contact with a porous medium |
US20040241659A1 (en) * | 2003-05-30 | 2004-12-02 | Applera Corporation | Apparatus and method for hybridization and SPR detection |
US20060246576A1 (en) | 2005-04-06 | 2006-11-02 | Affymetrix, Inc. | Fluidic system and method for processing biological microarrays in personal instrumentation |
US20140155272A1 (en) * | 2012-12-04 | 2014-06-05 | Src, Inc. | Use Of Diatomaceous Earth As The Base Substrate For Nucleic Acid Tags |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4591614A (en) * | 1983-10-07 | 1986-05-27 | The Johns Hopkins University | Preparation of oligodeoxyribonucleoside alkyl or arylphosphonates |
US4638032A (en) * | 1983-12-12 | 1987-01-20 | Genetics Institute, Inc. | Magnetic particles as supports for organic synthesis |
US4659774A (en) * | 1985-11-01 | 1987-04-21 | American Hoechst Corporation | Support for solid-phase oligonucleotide synthesis |
-
1985
- 1985-06-20 FR FR8509382A patent/FR2583772B1/fr not_active Expired
-
1986
- 1986-06-05 US US06/871,451 patent/US4780504A/en not_active Expired - Fee Related
- 1986-06-11 CA CA000511344A patent/CA1265756A/fr not_active Expired - Fee Related
- 1986-06-13 DE DE8686401289T patent/DE3665592D1/de not_active Expired
- 1986-06-13 EP EP86401289A patent/EP0206913B1/de not_active Expired
- 1986-06-17 JP JP61139397A patent/JPS61293553A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FR2583772A1 (fr) | 1986-12-26 |
EP0206913A1 (de) | 1986-12-30 |
FR2583772B1 (fr) | 1987-08-28 |
JPS61293553A (ja) | 1986-12-24 |
EP0206913B1 (de) | 1989-09-13 |
US4780504A (en) | 1988-10-25 |
CA1265756A (fr) | 1990-02-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |