DE3763314D1 - Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel. - Google Patents
Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel.Info
- Publication number
- DE3763314D1 DE3763314D1 DE8787109899T DE3763314T DE3763314D1 DE 3763314 D1 DE3763314 D1 DE 3763314D1 DE 8787109899 T DE8787109899 T DE 8787109899T DE 3763314 T DE3763314 T DE 3763314T DE 3763314 D1 DE3763314 D1 DE 3763314D1
- Authority
- DE
- Germany
- Prior art keywords
- carbon atoms
- straight
- chain
- branched
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4025—Esters of poly(thio)phosphonic acids
- C07F9/405—Esters of poly(thio)phosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19863623397 DE3623397A1 (de) | 1986-07-11 | 1986-07-11 | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3763314D1 true DE3763314D1 (de) | 1990-07-26 |
Family
ID=6304949
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19863623397 Withdrawn DE3623397A1 (de) | 1986-07-11 | 1986-07-11 | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
DE1996175038 Active DE19675038I2 (de) | 1986-07-11 | 1987-07-09 | Neue Diphosphonsaeurederivate Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE8787109900T Expired - Lifetime DE3781730D1 (de) | 1986-07-11 | 1987-07-09 | 1-hydroxy-3-(n-methyl-n-propylamino)propan-1,1-diphosphonsaeure verfahren zu dessen herstellung und diese verbindung enthaltende arzneimittel. |
DE8787109899T Expired - Lifetime DE3763314D1 (de) | 1986-07-11 | 1987-07-09 | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel. |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19863623397 Withdrawn DE3623397A1 (de) | 1986-07-11 | 1986-07-11 | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
DE1996175038 Active DE19675038I2 (de) | 1986-07-11 | 1987-07-09 | Neue Diphosphonsaeurederivate Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE8787109900T Expired - Lifetime DE3781730D1 (de) | 1986-07-11 | 1987-07-09 | 1-hydroxy-3-(n-methyl-n-propylamino)propan-1,1-diphosphonsaeure verfahren zu dessen herstellung und diese verbindung enthaltende arzneimittel. |
Country Status (27)
Country | Link |
---|---|
US (2) | US4927814A (de) |
EP (2) | EP0252504B1 (de) |
JP (2) | JP2563954B2 (de) |
KR (2) | KR950008997B1 (de) |
AT (2) | ATE54000T1 (de) |
AU (2) | AU598279B2 (de) |
BG (1) | BG60839B2 (de) |
CA (2) | CA1296739C (de) |
CS (1) | CS265242B2 (de) |
DD (1) | DD263992A5 (de) |
DE (4) | DE3623397A1 (de) |
DK (2) | DK168629B1 (de) |
ES (2) | ES2036190T3 (de) |
FI (2) | FI87221C (de) |
GE (1) | GEP20084347B (de) |
GR (2) | GR3000616T3 (de) |
HK (1) | HK87093A (de) |
HU (2) | HU201950B (de) |
IE (2) | IE60219B1 (de) |
IL (2) | IL83148A (de) |
LU (1) | LU88844I2 (de) |
MX (1) | MX9203375A (de) |
NL (1) | NL960032I2 (de) |
NZ (2) | NZ221027A (de) |
PT (1) | PT85301B (de) |
WO (1) | WO1988000590A1 (de) |
ZA (1) | ZA874877B (de) |
Families Citing this family (160)
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EP0317505A1 (de) * | 1987-11-13 | 1989-05-24 | Ciba-Geigy Ag | Neue Azacycloalkylalkandiphosphonsäuren |
US5190930A (en) * | 1987-12-11 | 1993-03-02 | Ciba-Geigy Corporation | Araliphatylaminoalkanediphosphonic acids |
US5110807A (en) * | 1988-12-01 | 1992-05-05 | Ciba-Geigy Corporation | Araliphatylaminoalkanediphosphonic acids |
EP0320455B1 (de) * | 1987-12-11 | 1993-06-09 | Ciba-Geigy Ag | Araliphatylaminoalkandiphosphonsäuren |
JPH07629B2 (ja) * | 1988-01-20 | 1995-01-11 | 山之内製薬株式会社 | (シクロアルキルアミノ)メチレンビス(フォスフォン酸)および該化合物を有効成分とする医薬 |
US4933472A (en) * | 1988-04-08 | 1990-06-12 | Yamanouchi Pharmaceutical Co., Ltd. | Substituted aminomethylenebis(phosphonic acid) derivatives |
DE3822650A1 (de) * | 1988-07-05 | 1990-02-01 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
WO1990005115A1 (en) * | 1988-11-01 | 1990-05-17 | Earl Philip Horwitz | Phosphonic acids and their uses in separation |
GB8825589D0 (en) * | 1988-11-02 | 1988-12-07 | Albright & Wilson | Purification |
TW198039B (de) * | 1988-11-28 | 1993-01-11 | Ciba Geigy Ag | |
US5154843A (en) * | 1989-02-08 | 1992-10-13 | The Lubrizol Corporation | Hydroxyalkane phosphonic acids and derivatives thereof and lubricants containing the same |
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US4987767A (en) * | 1989-06-09 | 1991-01-29 | Research Corporation Technologies, Inc. | Exposive detection screening system |
US5139786A (en) * | 1989-07-07 | 1992-08-18 | Ciba-Geigy Corporation | Topical formulations |
MX21452A (es) * | 1989-07-07 | 1994-01-31 | Ciba Geigy Ag | Preparaciones farmaceuticas que se administran en forma topica. |
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US5487897A (en) | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
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US5356887A (en) * | 1990-01-31 | 1994-10-18 | Merck & Co., Inc. | Pharmaceutical compositions containing insoluble calcium salts of amino-hydroxybutylidene bisphoshonic acids |
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IT1247034B (it) * | 1991-06-26 | 1994-12-12 | Gentili Ist Spa | Acidi dimetilamino-idrossi alchil difosfonici e loro sali, loro procedimento produttivo e composizioni farmaceutiche che li comprendono |
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DE4228552A1 (de) * | 1992-08-27 | 1994-03-03 | Boehringer Mannheim Gmbh | Diphosphonsäuren und deren Salze enthaltende Arzneimittel |
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US5728650A (en) * | 1993-10-07 | 1998-03-17 | Zeneca Limited | Herbicidal aza bisphosphonic acids and compositions containing the same |
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