DE3771272D1 - Pulsierendes arzneistoffabgabesystem. - Google Patents

Pulsierendes arzneistoffabgabesystem.

Info

Publication number
DE3771272D1
DE3771272D1 DE8787304315T DE3771272T DE3771272D1 DE 3771272 D1 DE3771272 D1 DE 3771272D1 DE 8787304315 T DE8787304315 T DE 8787304315T DE 3771272 T DE3771272 T DE 3771272T DE 3771272 D1 DE3771272 D1 DE 3771272D1
Authority
DE
Germany
Prior art keywords
delivery system
drug delivery
pulsating
pulsating drug
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787304315T
Other languages
English (en)
Inventor
David G Pope
Alan E Royce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3771272D1 publication Critical patent/DE3771272D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
DE8787304315T 1986-05-23 1987-05-15 Pulsierendes arzneistoffabgabesystem. Expired - Fee Related DE3771272D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/866,415 US4723958A (en) 1986-05-23 1986-05-23 Pulsatile drug delivery system

Publications (1)

Publication Number Publication Date
DE3771272D1 true DE3771272D1 (de) 1991-08-14

Family

ID=25347564

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787304315T Expired - Fee Related DE3771272D1 (de) 1986-05-23 1987-05-15 Pulsierendes arzneistoffabgabesystem.

Country Status (9)

Country Link
US (1) US4723958A (de)
EP (1) EP0246819B1 (de)
JP (1) JPS62283918A (de)
AU (1) AU595033B2 (de)
BR (1) BR8702654A (de)
CA (1) CA1272090A (de)
DE (1) DE3771272D1 (de)
NZ (1) NZ220178A (de)
ZA (1) ZA873696B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107661309A (zh) * 2016-07-28 2018-02-06 北京天衡药物研究院有限公司 一种组合型渗透泵制剂及其制备方法

Families Citing this family (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5000957A (en) * 1984-03-19 1991-03-19 Alza Corporation Dispenser comprising hydrophilic osmopolymer
US4844984A (en) * 1984-03-19 1989-07-04 Alza Corporation Dispensing system with means for increasing delivery of beneficial agent from the system
US4892778A (en) * 1987-05-27 1990-01-09 Alza Corporation Juxtaposed laminated arrangement
US5110597A (en) * 1987-06-25 1992-05-05 Alza Corporation Multi-unit delivery system
GB2206046B (en) * 1987-06-25 1991-04-03 Alza Corp Multi-unit delivery system
US4874388A (en) * 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US4957494A (en) * 1987-06-25 1990-09-18 Alza Corporation Multi-layer delivery system
US5023088A (en) * 1987-06-25 1991-06-11 Alza Corporation Multi-unit delivery system
US5499979A (en) * 1987-06-25 1996-03-19 Alza Corporation Delivery system comprising kinetic forces
AU3432689A (en) * 1988-03-24 1989-10-16 Bukh Meditec A/S Controlled release composition
US5062841A (en) * 1988-08-12 1991-11-05 The Regents Of The University Of California Implantable, self-regulating mechanochemical insulin pump
US4946456A (en) * 1988-08-26 1990-08-07 Alza Corp. Fluid imbibing pump activated by capillary action of a fabric or polymeric sleeve
US5135523A (en) * 1988-12-13 1992-08-04 Alza Corporation Delivery system for administering agent to ruminants and swine
US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
EP0424535A4 (en) * 1989-04-21 1991-10-16 Moskovsky Avtomobilestroitelny Institut (Vtuz-Zil) Device for controlled dosing of active substances into an operative medium
US5139023A (en) * 1989-06-02 1992-08-18 Theratech Inc. Apparatus and method for noninvasive blood glucose monitoring
NZ234227A (en) * 1989-06-30 1991-08-27 Smithkline Beecham Corp Delayed release dosage form
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
US5030216A (en) * 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
US5017381A (en) * 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system
US5922342A (en) * 1990-10-01 1999-07-13 Pharmacia & Upjohn Company Lateral edge coated controlled release pharmaceutical compositions
US5151093A (en) * 1990-10-29 1992-09-29 Alza Corporation Osmotically driven syringe with programmable agent delivery
AU1569292A (en) * 1991-03-12 1992-10-21 Alza Corporation Space- and stability-efficient delivery device
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5209746A (en) * 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
US5383873A (en) * 1992-12-09 1995-01-24 Regents Of The University Of Minnesota Smooth muscle chemical pacemaker
US7910624B1 (en) 1995-03-03 2011-03-22 The Trustees Of Boston University Compositions for the treatment of blood disorders
JP3971454B2 (ja) * 1993-10-29 2007-09-05 ザ トラスティーズ オブ ボストン ユニバーシティ 抗新生物剤としての酪酸、酪酸塩、および誘導体の生理学的に安定な組成物
ATE249816T1 (de) * 1994-01-20 2003-10-15 Agres Ltd Vorrichtung zur verabreichung von nützlichen stoffen an wiederkäuer
US5540665A (en) * 1994-01-31 1996-07-30 Alza Corporation Gas driven dispensing device and gas generating engine therefor
AU707955B2 (en) * 1994-06-22 1999-07-22 Controlled Release Technologies, Pty. Ltd. Controlled release device and method
WO1995035131A1 (en) * 1994-06-22 1995-12-28 Unasco Pty. Ltd. Controlled release device and method
US5672357A (en) * 1994-07-01 1997-09-30 Monsanto Company Method and device for implantation of large diameter objects in bovines
US5595752A (en) * 1994-07-01 1997-01-21 Monsanto Company Increasing dressing percentage and carcass weight in finishing beef cattle
US5837276A (en) * 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5582591A (en) * 1994-09-02 1996-12-10 Delab Delivery of solid drug compositions
US5522798A (en) * 1994-10-17 1996-06-04 Abbott Laboratories Control of a multi-channel drug infusion pump using a pharmacokinetic model
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
US6403647B1 (en) 1996-07-26 2002-06-11 Susan P. Perrine Pulsed administration of compositions for the treatment of blood disorders
EP0969869A2 (de) 1996-07-26 2000-01-12 Susan P. Perrine Zusammensetzung enthaltend einen induzierenden wikstoff und einen antiviralen wirkstoff zur behandlung von viralen und zellulären störungen
US5939456A (en) * 1996-07-26 1999-08-17 Perrine; Susan P. Pulsed administration of compositions for the treatment of blood disorders
US6725859B1 (en) 1997-01-22 2004-04-27 Charles River Laboratories Apparatus for delivering air-borne substances
US6607751B1 (en) * 1997-10-10 2003-08-19 Intellipharamaceutics Corp. Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum
WO1999040883A2 (en) * 1998-02-11 1999-08-19 Faller Douglas V Compositions and methods for the treatment of cystic fibrosis
US6322819B1 (en) 1998-10-21 2001-11-27 Shire Laboratories, Inc. Oral pulsed dose drug delivery system
CA2380111A1 (en) * 1999-08-03 2001-02-08 Smith & Nephew, Inc. Controlled release implantable devices
WO2001052815A1 (en) 2000-01-20 2001-07-26 Delsys Pharmaceutical Corporation Multi-step drug dosage forms
US6669954B2 (en) 2000-01-25 2003-12-30 John R. Crison Controlled release of drugs
US6616652B1 (en) 2000-02-15 2003-09-09 Microsolutions, Inc. Osmotic pump delivery system with pre-hydrated membrane(s) and/or primable catheter
US6464688B1 (en) 2000-02-15 2002-10-15 Microsolutions, Inc. Osmotic pump delivery system with flexible drug compartment
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) * 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US6632217B2 (en) * 2001-04-19 2003-10-14 Microsolutions, Inc. Implantable osmotic pump
AUPR602501A0 (en) * 2001-06-29 2001-07-26 Smart Drug Systems Inc Sustained release pharmaceutical composition
AUPR839001A0 (en) * 2001-10-19 2001-11-15 Eli Lilly And Company Dosage form, device and methods of treatment
US7160551B2 (en) * 2002-07-09 2007-01-09 The Board Of Trustees Of The University Of Illinois Injectable system for controlled drug delivery
US6913768B2 (en) * 2002-09-24 2005-07-05 Shire Laboratories, Inc. Sustained release delivery of amphetamine salts
US8313775B2 (en) * 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
JP2006528185A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8313776B2 (en) * 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
EP1653925A1 (de) * 2003-08-11 2006-05-10 Advancis Pharmaceutical Corporation Robustes pellet
JP2007502294A (ja) * 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
CA2535780A1 (en) * 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
JP2007513869A (ja) * 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
NZ529177A (en) * 2003-10-24 2005-12-23 Agres Ltd Administration process for a delivery device that releases the active agent over several days
US20050142187A1 (en) * 2003-12-24 2005-06-30 Treacy Donald J.Jr. Enhanced absorption of modified release dosage forms
WO2006014427A1 (en) * 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Tablet for pulsed delivery
EA200801080A1 (ru) * 2005-10-14 2009-02-27 Х. Лундбекк А/С Стабильные фармацевтические лекарственные формы, содержащие эсциталопрам и бупропион
KR20080080094A (ko) * 2005-10-14 2008-09-02 하. 룬트벡 아크티에 셀스카브 에스시탈로프람 및 부프로피온의 저용량 조합물을 이용한중추신경계 장애의 치료 방법
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
CN104825397A (zh) 2006-04-03 2015-08-12 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US10208158B2 (en) 2006-07-10 2019-02-19 Medipacs, Inc. Super elastic epoxy hydrogel
US9995295B2 (en) 2007-12-03 2018-06-12 Medipacs, Inc. Fluid metering device
WO2010105112A1 (en) * 2009-03-11 2010-09-16 Hemaquest Pharmaceuticals, Inc. Detection of short-chain fatty acids in biological samples
EP2459116B1 (de) 2009-07-31 2019-10-09 Boehringer Ingelheim Animal Health USA Inc. Kapseln mit verzögerter freisetzung
EP2459184A1 (de) 2009-07-31 2012-06-06 The Brigham and Women's Hospital, Inc. Modulation der sgk1-expression bei th17-zellen zur modulation von th17-vermittelten immunreaktionen
US9238102B2 (en) 2009-09-10 2016-01-19 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
WO2011038224A1 (en) 2009-09-24 2011-03-31 Trustees Of Boston University Methods for treating viral disorders
WO2011072086A1 (en) 2009-12-08 2011-06-16 Hemaquest Pharmaceuticals, Inc. Methods and low dose regimens for treating red blood cell disorders
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
US20110245154A1 (en) 2010-03-11 2011-10-06 Hemaquest Pharmaceuticals, Inc. Methods and Compositions for Treating Viral or Virally-Induced Conditions
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
EP2670426B1 (de) 2011-01-31 2017-05-10 The General Hospital Corporation Multimodale trail-moleküle und ihre verwendungen in zelltherapien
WO2012129237A2 (en) 2011-03-20 2012-09-27 Trustees Of Boston University Therapeutic agent for emphysema and copd
EP2704726B1 (de) 2011-05-04 2018-10-31 Trustees of Boston University Protonenantriebskraftstimulation zur potenzierung von aminoglycosid-antibiotika gegen persistente bakterien
WO2013003697A1 (en) 2011-06-30 2013-01-03 Trustees Of Boston University Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
WO2013055985A1 (en) 2011-10-12 2013-04-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
US9243037B2 (en) 2011-11-10 2016-01-26 Trustees Of Boston College Gramicidin a mutants that function as antibiotics with improved solubility and reduced toxicity
WO2013082275A1 (en) 2011-11-30 2013-06-06 Trustees Of Boston College Inhibitors of phosphodiesterases 11 (pde11) and methods of use to elevate cortisol production
EP2847249A4 (de) 2012-03-14 2016-12-28 Medipacs Inc Intelligente polymermaterialien mit überschüssigen reaktiven molekülen
JP2015525781A (ja) 2012-07-31 2015-09-07 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． 免疫応答の調節
EP2890720B1 (de) 2012-08-30 2019-07-17 The General Hospital Corporation Zusammensetzungen und verfahren zur behandlung von krebs
US20140088345A1 (en) * 2012-09-27 2014-03-27 Palo Alto Research Center Incorporated Single channel, multiple drug delivery device and methods
KR102229873B1 (ko) 2012-10-12 2021-03-19 더 브리검 앤드 우먼즈 하스피털, 인크. 면역 반응의 향상
WO2014130922A1 (en) 2013-02-25 2014-08-28 Trustees Of Boston University Compositions and methods for treating fungal infections
CA2924141C (en) 2013-08-22 2022-06-07 The General Hospital Corporation 5-amino 4-cyano substituted oxazole and thiazole derivatives as inhibitors of human 12/15-lipoxygenase
EP3038625A4 (de) 2013-08-29 2017-08-23 Trustees of Boston University Stoffwechselzwischenprodukte zur potenzierung von aminoglycosid-antibiotika bei bakteriellen infektionen
EP3074039A4 (de) 2013-11-26 2017-10-11 The Brigham and Women's Hospital, Inc. Zusammensetzungen und verfahren zur modulierung einer immunreaktion
AU2014362307A1 (en) 2013-12-11 2016-06-30 The General Hospital Corporation Use of mullerian inhibiting substance (MIS) proteins for contraception and ovarian reserve preservation
EP3082471B1 (de) 2013-12-16 2017-10-04 Massachusetts Institute Of Technology Angereicherte mikronährstoffsalzformulierungen
EP3119913B1 (de) 2014-03-21 2021-01-06 The Brigham and Women's Hospital, Inc. Verfahren und zusammensetzungen zur behandlung von immunbedingten erkrankungen oder störungen und/oder therapieüberwachung
CA2983796A1 (en) 2014-04-25 2015-10-29 The Brigham And Women's Hospital, Inc. Compositions and methods for treating subjects with immune-mediated diseases
WO2015164364A2 (en) 2014-04-25 2015-10-29 The Brigham And Women's Hospital, Inc. Methods to manipulate alpha-fetoprotein (afp)
WO2016044707A1 (en) 2014-09-18 2016-03-24 Cedars-Sinai Medical Center Compositions and methods for treating fibrosis
CN107530423B (zh) 2015-01-14 2022-04-05 布里格姆及妇女医院股份有限公司 用抗lap单克隆抗体治疗癌症
EP4194001A1 (de) 2015-04-22 2023-06-14 Cedars-Sinai Medical Center Enterisch verabreichte bittere oligopeptide zur behandlung von typ-2-diabetes und fettleibigkeit
EP3303286B1 (de) 2015-06-01 2023-10-04 Cedars-Sinai Medical Center An rela von nf-kb anbindende verbindungen zur verwendung bei der behandlung von krebs
CN116712552A (zh) 2015-06-19 2023-09-08 波士顿大学托管委员会 用于治疗疱疹病毒诱导的病况的方法和组合物
BR112018001441A2 (pt) 2015-07-28 2018-09-11 Vyome Biosciences Pvt Ltd antibacterianos terapêuticos e profiláticos
EP3355909B1 (de) 2015-09-28 2023-06-07 Children's Hospital Los Angeles Verfahren zur behandlung von durch erbb4-positive proinflammatorische makrophagen vermittelte erkrankungen
US20190255107A1 (en) 2015-10-09 2019-08-22 The Brigham And Women's Hospital, Inc. Modulation of novel immune checkpoint targets
US20200016202A1 (en) 2016-10-07 2020-01-16 The Brigham And Women's Hospital, Inc. Modulation of novel immune checkpoint targets
EP3752532A1 (de) 2018-02-12 2020-12-23 Diabetes-Free, Inc. Verbesserte antagonistische monoklonale anti-human-cd40-antikörper
WO2020102454A1 (en) 2018-11-13 2020-05-22 Regents Of The University Of Minnesota Cd40 targeted peptides and uses thereof
CN109589491B (zh) * 2019-01-29 2024-01-09 上海安翰医疗技术有限公司 自动给药装置
KR20220034736A (ko) 2019-05-31 2022-03-18 비락타 서브시디어리 인크. 히스톤 데아세틸라제 억제제를 사용하여 바이러스 관련 암을 치료하는 방법
JP2023553202A (ja) 2020-12-08 2023-12-20 ルミナント バイオテク コーポレーション リミテッド 動物に物質を送達するための装置および方法の改善

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3656483A (en) * 1970-01-15 1972-04-18 Biolog Concepts Inc Intrauterine medicator
US3760806A (en) * 1971-01-13 1973-09-25 Alza Corp Helical osmotic dispenser with non-planar membrane
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3760804A (en) * 1971-01-13 1973-09-25 Alza Corp Improved osmotic dispenser employing magnesium sulphate and magnesium chloride
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US4320758A (en) * 1979-05-07 1982-03-23 Alza Corporation Osmotically driven fluid dispenser
NZ197543A (en) * 1980-07-02 1984-12-14 Commw Scient Ind Res Org Controlled release compositions for inclusion in intraruminal devices
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4381780A (en) * 1981-01-19 1983-05-03 Research Corporation Sustained release delivery system
NZ203203A (en) * 1982-02-16 1985-09-13 Commw Scient Ind Res Org Controlled release device:gas diffusion limited
US4439196A (en) * 1982-03-18 1984-03-27 Merck & Co., Inc. Osmotic drug delivery system
US4564363A (en) * 1983-07-13 1986-01-14 Smithkline Beckman Corporation Delayed action assembly
GB2150434B (en) * 1983-12-01 1987-11-04 Alza Corp Constant rate release systems
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
GB2155889B (en) * 1984-03-21 1988-03-02 Alza Corp Dispenser-capsule
GR851195B (de) * 1984-06-02 1985-11-25 Castex Prod

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107661309A (zh) * 2016-07-28 2018-02-06 北京天衡药物研究院有限公司 一种组合型渗透泵制剂及其制备方法

Also Published As

Publication number Publication date
NZ220178A (en) 1989-10-27
ZA873696B (en) 1987-11-18
AU595033B2 (en) 1990-03-22
CA1272090A (en) 1990-07-31
AU7331087A (en) 1987-11-26
US4723958A (en) 1988-02-09
BR8702654A (pt) 1988-02-23
JPS62283918A (ja) 1987-12-09
EP0246819A3 (en) 1988-04-27
EP0246819B1 (de) 1991-07-10
EP0246819A2 (de) 1987-11-25

Similar Documents

Publication Publication Date Title
DE3771272D1 (de) Pulsierendes arzneistoffabgabesystem.
DE3750619D1 (de) System zur Abgabe von Arzneistoffen.
DK453585D0 (da) Laegemiddel-indgivelsessystem
IT8521922A0 (it) Sistema di somministrazione di farmaci.
GB2185397B (en) Drug delivery system
DE69133445D1 (de) Arzneistoffabgabesystem
DE3783437D1 (de) Heilmittel.
NO881664L (no) Avgivelsessystemer for farmakologiske preparater.
NL194604B (nl) Implanteerbaar geneesmiddelpompsysteem.
DE3885392D1 (de) Dialysesystem.
DE3789665D1 (de) Blutpumpsystem.
NO882897D0 (no) Avleveringssystem for legemidler.
DK528988D0 (da) Laegemiddelafgivelsessystem
FI875098A (fi) Transdermalt terapeutiskt system.
DE3789673T2 (de) Selbstansaugendes Zufuhrsystem zur Verabreichung eines Heilmittels.
NO874193D0 (no) Farmasoeytiske preparater.
NO891130D0 (no) Doseringspumpesystem.
IT8620803A0 (it) Sistemi terapeutico per la cessione controllata di farmaci.
FI875616A (fi) Farmaceutiska blandningar.
ATE63060T1 (de) Therapeutisches system mit geregelter wirkstoffabgabe.
ATE60716T1 (de) Medikamentenabgabesystem.
FI865010A0 (fi) Farmaceutisk aemnesklass.
ATE104534T1 (de) Blutpumpsystem.
IL80330A0 (en) Drug delivery system
GB8616617D0 (en) Drug delivery system

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee