DE3779183D1 - Feste pharmaceutische zubereitung mit verlaengerter wirkstofffreigabe und verfahren zur herstellung. - Google Patents

Feste pharmaceutische zubereitung mit verlaengerter wirkstofffreigabe und verfahren zur herstellung.

Info

Publication number
DE3779183D1
DE3779183D1 DE8787850098T DE3779183T DE3779183D1 DE 3779183 D1 DE3779183 D1 DE 3779183D1 DE 8787850098 T DE8787850098 T DE 8787850098T DE 3779183 T DE3779183 T DE 3779183T DE 3779183 D1 DE3779183 D1 DE 3779183D1
Authority
DE
Germany
Prior art keywords
production
active substance
pharmaceutical preparation
solid pharmaceutical
substance release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787850098T
Other languages
English (en)
Inventor
Karl-Erik Lennart Falk
Sven Morgan Hugosson
Adam Rosinski
John Albert Sjoegren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20364135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3779183(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hassle AB filed Critical Hassle AB
Application granted granted Critical
Publication of DE3779183D1 publication Critical patent/DE3779183D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
DE8787850098T 1986-04-11 1987-03-25 Feste pharmaceutische zubereitung mit verlaengerter wirkstofffreigabe und verfahren zur herstellung. Expired - Lifetime DE3779183D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8601624A SE8601624D0 (sv) 1986-04-11 1986-04-11 New pharmaceutical preparations

Publications (1)

Publication Number Publication Date
DE3779183D1 true DE3779183D1 (de) 1992-06-25

Family

ID=20364135

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787850098T Expired - Lifetime DE3779183D1 (de) 1986-04-11 1987-03-25 Feste pharmaceutische zubereitung mit verlaengerter wirkstofffreigabe und verfahren zur herstellung.

Country Status (34)

Country Link
US (1) US4803081A (de)
EP (1) EP0249587B1 (de)
JP (1) JPH0778016B2 (de)
KR (2) KR870009720A (de)
CN (1) CN1025150C (de)
AT (1) ATE76288T1 (de)
AU (1) AU602677B2 (de)
CA (1) CA1304294C (de)
CS (1) CS270560B2 (de)
CY (1) CY1826A (de)
DD (1) DD263231A5 (de)
DE (1) DE3779183D1 (de)
DK (1) DK173033B1 (de)
DZ (1) DZ1067A1 (de)
EG (1) EG18265A (de)
ES (1) ES2031929T3 (de)
FI (1) FI91826C (de)
GR (1) GR3005286T3 (de)
HK (1) HK26795A (de)
HU (1) HU204699B (de)
IE (1) IE59419B1 (de)
IS (1) IS1553B (de)
MY (1) MY101553A (de)
NO (1) NO174795B (de)
NZ (1) NZ219633A (de)
PH (1) PH22494A (de)
PL (1) PL265078A1 (de)
PT (1) PT84663B (de)
SE (1) SE8601624D0 (de)
SG (1) SG4295G (de)
SU (1) SU1743332A3 (de)
UA (1) UA12336A (de)
YU (1) YU47258B (de)
ZA (1) ZA871911B (de)

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US5834496A (en) * 1991-12-02 1998-11-10 Sepracor, Inc. Methods for treating hypertension using optically pure S(-) felodipine
US5681812A (en) * 1991-12-10 1997-10-28 Rush Presbyterian-St. Luke's Medical Center Methods and compositions for reducing multidrug resistance
WO1993011668A1 (en) * 1991-12-10 1993-06-24 Rush-Presbyterian-St. Luke's Medical Center Methods and compositions for reducing multi-drug resistance
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
DE69307505T2 (de) 1992-05-13 1997-07-24 Sandoz Ag Opthalmische zusammensetzungen enthaltend ein cyclosporin
US5472711A (en) * 1992-07-30 1995-12-05 Edward Mendell Co., Inc. Agglomerated hydrophilic complexes with multi-phasic release characteristics
RU2121830C1 (ru) * 1992-09-18 1998-11-20 Яманоути Фармасьютикал Ко., ЛТД Гидрогелевый препарат с длительным высвобождением лекарства
JP3598049B2 (ja) * 1992-09-18 2004-12-08 山之内製薬株式会社 ハイドロゲル徐放性製剤
EP0589843B1 (de) 1992-09-25 2001-11-28 Novartis AG Cyclosporin enthaltende pharmazeutische Zusammensetzungen
BE1006990A5 (nl) * 1993-04-22 1995-02-07 Univ Gent Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen.
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US6726930B1 (en) * 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
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US20060263428A1 (en) * 1993-09-20 2006-11-23 Eugenio Cefali Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics
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US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
DE4340781C3 (de) * 1993-11-30 2000-01-27 Novartis Ag Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung
US5945125A (en) * 1995-02-28 1999-08-31 Temple University Controlled release tablet
US5783212A (en) * 1996-02-02 1998-07-21 Temple University--of the Commonwealth System of Higher Education Controlled release drug delivery system
ES2322405T3 (es) 1996-07-08 2009-06-19 Penwest Pharmaceuticals Co. Matriz de liberacion controlada para farmacos insolubles en dosis elevadas.
CN1246058A (zh) 1997-01-30 2000-03-01 诺瓦提斯公司 包含环孢菌素a的无油药物组合物
US5895663A (en) * 1997-07-31 1999-04-20 L. Perrigo Company Pseudoephedrine hydrochloride extended-release tablets
AR016827A1 (es) 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
AR017512A1 (es) 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
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FR2802424B1 (fr) * 1999-12-17 2002-02-15 Adir Comprime matriciel permettant la liberation prolongee de trimetazidine apres administration par voie orale
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CA2311734C (en) 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
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WO2002056883A1 (en) * 2001-01-18 2002-07-25 Wockhardt Limited Preparation of micron-size felodipine particles by microfluidization
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JP2005529059A (ja) * 2001-09-28 2005-09-29 マクニール−ピーピーシー・インコーポレイテッド 改質した放出用の投薬形態
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
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WO2003084517A2 (fr) 2002-04-09 2003-10-16 Flamel Technologies Suspension orale de microcapsules d’amoxicilline
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
US20030211149A1 (en) * 2002-05-07 2003-11-13 Sherman Bernard Charles Extended release tablets comprising felodipine
JP4563642B2 (ja) * 2002-05-31 2010-10-13 ワトソン ラボラトリーズ、インコーポレイテッド 医薬製剤
FR2842736B1 (fr) 2002-07-26 2005-07-22 Flamel Tech Sa Formulation pharmaceutique orale sous forme d'une pluralite de microcapsules permettant la liberation prolongee de principe(s) actif(s) peu soluble(s)
FR2842735B1 (fr) 2002-07-26 2006-01-06 Flamel Tech Sa Microcapsules a liberation modifiee de principes actifs peu solubles pour l'administration per os
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
EP1572190B1 (de) * 2002-12-17 2007-04-18 Abbott GmbH & Co. KG Fenofibratsäure enthaltende pharmazeutische zusammensetzung und deren physiologisch verträgliche salze und derivate
US7259186B2 (en) * 2002-12-17 2007-08-21 Abbott Laboratories Salts of fenofibric acid and pharmaceutical formulations thereof
US20050032879A1 (en) * 2003-08-07 2005-02-10 Temple Okarter Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases
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US8987322B2 (en) * 2003-11-04 2015-03-24 Circ Pharma Research And Development Limited Pharmaceutical formulations for carrier-mediated transport statins and uses thereof
WO2005079752A2 (en) * 2004-02-11 2005-09-01 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
KR100598326B1 (ko) * 2004-04-10 2006-07-10 한미약품 주식회사 HMG-CoA 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법
US20080152714A1 (en) * 2005-04-08 2008-06-26 Yi Gao Pharmaceutical Formulations
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DE2714065A1 (de) * 1977-03-30 1978-10-12 Boehringer Mannheim Gmbh Instillationszubereitung
JPS5495721A (en) * 1978-01-11 1979-07-28 Nippon Kayaku Co Ltd Nifedipine preparation
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JPS58109412A (ja) * 1981-12-23 1983-06-29 Toa Eiyou Kagaku Kogyo Kk ニフエジピン固形製剤
DE3318649A1 (de) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen Zweiphasenformulierung
DE3400106A1 (de) * 1984-01-04 1985-07-11 Klaus-Dieter Dr. 3550 Marburg Bremecker Pharmazeutische zubereitungen mit gesteuerter arzneistoff-freisetzung
KR850700212A (ko) * 1984-03-21 1985-12-26 죠지 드모트 서방성 약제학적 캼셀제
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Also Published As

Publication number Publication date
GR3005286T3 (de) 1993-05-24
UA12336A (uk) 1996-12-25
EG18265A (en) 1992-12-30
PH22494A (en) 1988-09-12
EP0249587B1 (de) 1992-05-20
SE8601624D0 (sv) 1986-04-11
JPS62242613A (ja) 1987-10-23
CY1826A (en) 1995-12-01
CS258787A2 (en) 1989-11-14
KR870009720A (ko) 1987-11-30
KR950002147B1 (ko) 1995-03-14
PT84663B (pt) 1989-11-30
IS1553B (is) 1994-08-10
YU47258B (sh) 1995-01-31
JPH0778016B2 (ja) 1995-08-23
HUT43786A (en) 1987-12-28
FI871585A (fi) 1987-10-12
IE59419B1 (en) 1994-02-23
AU7004387A (en) 1987-10-15
CA1304294C (en) 1992-06-30
ES2031929T3 (es) 1993-01-01
NO174795B (no) 1994-04-05
NO174795C (de) 1994-07-13
PL265078A1 (en) 1988-07-21
DK173033B1 (da) 1999-11-29
DD263231A5 (de) 1988-12-28
FI871585A0 (fi) 1987-04-10
CN87102758A (zh) 1987-10-21
NO871199L (no) 1987-10-12
SG4295G (en) 1995-06-16
SU1743332A3 (ru) 1992-06-23
YU40787A (sh) 1992-09-07
DK154987D0 (da) 1987-03-26
FI91826C (fi) 1994-08-25
NO871199D0 (no) 1987-03-23
PT84663A (en) 1987-05-01
NZ219633A (en) 1989-11-28
IS3214A7 (is) 1987-10-12
EP0249587A1 (de) 1987-12-16
CS270560B2 (en) 1990-07-12
AU602677B2 (en) 1990-10-25
HU204699B (en) 1992-02-28
MY101553A (en) 1991-12-17
CN1025150C (zh) 1994-06-29
IE870925L (en) 1987-10-11
ATE76288T1 (de) 1992-06-15
FI91826B (fi) 1994-05-13
DZ1067A1 (fr) 2004-09-13
HK26795A (en) 1995-03-10
KR890001521A (ko) 1989-03-27
US4803081A (en) 1989-02-07
ZA871911B (en) 1987-12-30
DK154987A (da) 1987-10-12

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