DE3851433T2 - Biologische probenmischvorrichtung und verfahren hierzu. - Google Patents

Biologische probenmischvorrichtung und verfahren hierzu.

Info

Publication number
DE3851433T2
DE3851433T2 DE3851433T DE3851433T DE3851433T2 DE 3851433 T2 DE3851433 T2 DE 3851433T2 DE 3851433 T DE3851433 T DE 3851433T DE 3851433 T DE3851433 T DE 3851433T DE 3851433 T2 DE3851433 T2 DE 3851433T2
Authority
DE
Germany
Prior art keywords
container
biological sample
sample mixing
mixing device
method therefor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3851433T
Other languages
English (en)
Other versions
DE3851433D1 (de
Inventor
Todd Lary
Jorge Quintana
Osvaldo Miranda
John Dechristopher
John Hollinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coulter Corp
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Corp filed Critical Coulter Corp
Application granted granted Critical
Publication of DE3851433D1 publication Critical patent/DE3851433D1/de
Publication of DE3851433T2 publication Critical patent/DE3851433T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/22—Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00524—Mixing by agitating sample carrier
DE3851433T 1987-11-10 1988-11-09 Biologische probenmischvorrichtung und verfahren hierzu. Expired - Fee Related DE3851433T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/119,018 US4845025A (en) 1987-11-10 1987-11-10 Biological sample mixing apparatus and method
PCT/US1988/004022 WO1989004484A1 (en) 1987-11-10 1988-11-09 Biological sample mixing apparatus and method

Publications (2)

Publication Number Publication Date
DE3851433D1 DE3851433D1 (de) 1994-10-13
DE3851433T2 true DE3851433T2 (de) 1995-01-19

Family

ID=22382147

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3851433T Expired - Fee Related DE3851433T2 (de) 1987-11-10 1988-11-09 Biologische probenmischvorrichtung und verfahren hierzu.

Country Status (7)

Country Link
US (1) US4845025A (de)
EP (1) EP0353264B1 (de)
JP (1) JPH06103299B2 (de)
AT (1) ATE111223T1 (de)
CA (1) CA1322325C (de)
DE (1) DE3851433T2 (de)
WO (1) WO1989004484A1 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238812A (en) * 1987-03-13 1993-08-24 Coulter Corporation Method and apparatus for rapid mixing of small volumes for enhancing biological reactions
US5215376A (en) * 1989-09-08 1993-06-01 Becton, Dickinson And Company Method for causing vortices in a test tube
US5005981A (en) * 1989-09-08 1991-04-09 Becton, Dickinson And Company Apparatus for method for causing vortices in a test tube
EP0418026B1 (de) * 1989-09-13 1994-11-30 Kabushiki Kaisha Tiyoda Seisakusho Gerät zur Zellenvorbehandlung für Durchfluss-Zytometrie
US5203385A (en) * 1992-03-31 1993-04-20 Donald Waber Apparatus and process for automatically reconstituting dry materials, especially pharmaceuticals
US5372425A (en) * 1992-08-31 1994-12-13 New Brunswick Scientific Co., Inc. Cushioned restraining device for shaker apparatus
US6812032B1 (en) * 1993-01-21 2004-11-02 Cdc Technologies, Inc. Apparatus and method for making a plurality of reagent mixtures and analyzing particle distributions of the reagent mixtures
US5439645A (en) * 1993-01-25 1995-08-08 Coulter Corporation Apparatus for automatically, selectively handling multiple, randomly associated hematological samples
US6861265B1 (en) 1994-10-14 2005-03-01 University Of Washington Flow cytometer droplet formation system
US5602349A (en) * 1994-10-14 1997-02-11 The University Of Washington Sample introduction system for a flow cytometer
US5602039A (en) * 1994-10-14 1997-02-11 The University Of Washington Flow cytometer jet monitor system
US5643796A (en) * 1994-10-14 1997-07-01 University Of Washington System for sensing droplet formation time delay in a flow cytometer
JPH10507524A (ja) * 1994-10-14 1998-07-21 ユニバーシティ オブ ワシントン 高速フローサイトメータ液滴形成システム
US5840254A (en) 1995-06-02 1998-11-24 Cdc Technologies, Inc. Apparatus for mixing fluids for analysis
US5744099A (en) * 1995-09-15 1998-04-28 Cytek Development Inc. Apparatus for transfer of biological fluids
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
CA2279574C (en) 1997-01-31 2007-07-24 The Horticulture & Food Research Institute Of New Zealand Ltd. Optical apparatus
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
AU3454699A (en) * 1998-03-30 1999-10-18 Friedrich Srienc A flow injection flow cytometry system for on-line monitoring of bioreactors andmethod for monitoring
US6106718A (en) * 1998-07-01 2000-08-22 Biochem Technology, Inc. Enhanced denitrification process by monitoring and controlling carbonaceous nutrient addition
WO2000002031A1 (en) * 1998-07-07 2000-01-13 Lamina, Inc. Improved method for mixing and processing specimen samples
US6830935B1 (en) 1998-07-07 2004-12-14 Lamina, Inc. Method for mixing and processing specimen samples
NZ509434A (en) 1998-07-30 2004-03-26 Univ Colorado State Res Found Equine system for non-surgical artificial insemination
US6143246A (en) * 1998-08-18 2000-11-07 Biochem Technology, Inc. Apparatus for measuring ammonia in biochemical processes
US5976888A (en) * 1998-12-07 1999-11-02 Biochem Technology, Inc. Method for measuring NOx in biochemical processes
US6605475B1 (en) * 1999-04-16 2003-08-12 Perspective Biosystems, Inc. Apparatus and method for sample delivery
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
CA2408939C (en) 2000-05-09 2011-11-08 Xy, Inc. High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
WO2002043486A1 (en) 2000-11-29 2002-06-06 Xy, Inc. System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
WO2002092247A1 (en) 2001-05-17 2002-11-21 Cytomation, Inc. Flow cytometer with active automated optical alignment system
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
US20040214314A1 (en) * 2001-11-02 2004-10-28 Friedrich Srienc High throughput bioreactor
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
MXPA05001100A (es) 2002-08-01 2005-04-28 Xy Inc Sistema de separacion de baja presion para celulas de esperma.
MXPA05001654A (es) 2002-08-15 2005-10-18 Xy Inc Citometro de flujo de alta resolucion.
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
EP1419820A1 (de) * 2002-11-14 2004-05-19 F. Hoffmann-La Roche Ag Verfahren, Vorrichtung und Reaktionbehälter zur Bearbeitung von biologischen Proben
US8323984B2 (en) * 2002-12-19 2012-12-04 Beckman Coulter, Inc. Method and apparatus for mixing blood samples for cell analysis
MX347048B (es) 2003-03-28 2017-04-07 Inguran Llc * Aparato de muestreo digital y métodos para separar partículas.
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
US7178978B2 (en) * 2003-09-08 2007-02-20 Boston Scientific Santa Rosa Corp., Fluid mixing apparatus and method
CA2561661C (en) 2004-03-29 2015-11-24 Monsanto Technology Llc Sperm suspensions for sorting into x or y chromosome-bearing enriched populations
DE602004006508T2 (de) * 2004-06-07 2008-01-31 The Automation Partnership (Cambridge) Ltd., Royston Rührsystem für Zellkultur
AR049732A1 (es) 2004-07-22 2006-08-30 Monsanto Co Proceso para enriquecer una poblacion de celulas de esperma
PT1771729E (pt) 2004-07-27 2015-12-31 Beckman Coulter Inc Acentuação da discriminação da citometria de fluxo com transformação geométrica
US7340957B2 (en) 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
US7835000B2 (en) 2006-11-03 2010-11-16 Los Alamos National Security, Llc System and method for measuring particles in a sample stream of a flow cytometer or the like
ATE538377T1 (de) 2007-04-02 2012-01-15 Acoustic Cytometry Systems Inc Verfahren zur verbesserten analyse von in einem akustischen feld fokussierten zellen und partikeln
US8083068B2 (en) 2007-04-09 2011-12-27 Los Alamos National Security, Llc Apparatus for separating particles utilizing engineered acoustic contrast capture particles
US7837040B2 (en) * 2007-04-09 2010-11-23 Los Alamos National Security, Llc Acoustic concentration of particles in fluid flow
US7883265B2 (en) * 2007-06-01 2011-02-08 Applied Biosystems, Llc Devices, systems, and methods for preparing emulsions
US8528406B2 (en) * 2007-10-24 2013-09-10 Los Alamos National Security, LLP Method for non-contact particle manipulation and control of particle spacing along an axis
US8263407B2 (en) 2007-10-24 2012-09-11 Los Alamos National Security, Llc Method for non-contact particle manipulation and control of particle spacing along an axis
US8266951B2 (en) 2007-12-19 2012-09-18 Los Alamos National Security, Llc Particle analysis in an acoustic cytometer
US8714014B2 (en) 2008-01-16 2014-05-06 Life Technologies Corporation System and method for acoustic focusing hardware and implementations
US8785207B2 (en) * 2008-09-12 2014-07-22 Sri International Method and apparatus for measuring multiple parameters in-situ of a sample collected from environmental systems
US8307541B2 (en) * 2008-12-23 2012-11-13 Optimize Technologies, Inc. Assembly for placing an insert into communication with an analytical chemical instrument
DE102012208707A1 (de) * 2012-05-24 2013-12-12 Hamilton Bonaduz Ag Probenverarbeitungssystem zum Verarbeiten von biologischen Proben
CN204134550U (zh) * 2014-09-25 2015-02-04 深圳市奥特库贝科技有限公司 一种用于磁颗粒混匀的装置
US11291931B2 (en) 2014-12-15 2022-04-05 Akadeum Life Sciences, Inc. Method and system for buoyant separation
CN107206291A (zh) 2014-12-15 2017-09-26 爱卡德姆生命科学有限责任公司 用于浮力分离的方法和系统
GB2537618B (en) * 2015-04-20 2021-09-08 Orbital Energy Group Inc Sorbent Tube Holder
KR101728711B1 (ko) * 2015-09-03 2017-04-21 바디텍메드(주) 무개(capless) 튜브를 이용한 시료 혼합 장치 및 방법
WO2018079885A1 (ko) * 2016-10-28 2018-05-03 바디텍메드(주) 무개 튜브를 이용한 시료 혼합 장치 및 방법
CN112437692B (zh) 2018-07-09 2022-06-24 爱卡德姆生命科学公司 用于有浮力颗粒处理的系统和方法
US11819842B2 (en) 2021-08-26 2023-11-21 Akadeum Life Sciences, Inc. Method and system for buoyant separation

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US547596A (en) * 1895-10-08 Allen c
US982156A (en) * 1910-08-24 1911-01-17 Oscar G Miltz Churn.
US1852376A (en) * 1929-09-16 1932-04-05 William H Rees Weighing apparatus
US2480502A (en) * 1947-11-14 1949-08-30 William H Nieder Cleaning machine for small parts, particularly watch or clock parts
US2779510A (en) * 1954-09-27 1957-01-29 Union Carbide & Carbon Corp Vibrational dispenser for forming solid gas mixtures
US2828949A (en) * 1954-10-22 1958-04-01 Fond Emanuele Paterno Stirring device
US2846201A (en) * 1955-10-27 1958-08-05 Mermelstein Morris Paint mixing device
US3061280A (en) * 1959-04-06 1962-10-30 Kraft Scient Corp Apparatus for mixing fluent material
NL301310A (de) * 1960-07-02
US3220704A (en) * 1964-02-25 1965-11-30 Bristol Myers Co Machine for feeding and agitating
US3353796A (en) * 1965-05-17 1967-11-21 Donald E Roberts Vibratory burnishing system with metered feed
US3975001A (en) * 1973-10-19 1976-08-17 American Hospital Supply Corporation Apparatus for mixing fluids held in tubes
US3991627A (en) * 1975-11-28 1976-11-16 Block Engineering, Inc. Alignment device for sample containers
US4162129A (en) * 1977-08-29 1979-07-24 Wine Breather, Inc. Wine aerator
US4305668A (en) * 1980-04-08 1981-12-15 Scientific Manufacturing Industries, Inc. Vortexer
JPS57171265A (en) * 1981-04-14 1982-10-21 Lion Corp Method for automatic pre-processing specimen for analysis
JPS57171266A (en) * 1981-04-14 1982-10-21 Sunstar Kinzoku Kk Apparatus for examining mixed reagent
DE3220879A1 (de) * 1982-06-03 1983-12-08 Gebr. Liebisch, 4800 Bielefeld Reagenzglasschuettler zum mischen und aufwirbeln von analysenfluessigkeiten
JPS6081B2 (ja) * 1982-07-26 1985-01-05 サヌキ工業株式会社 自動抽出装置
US4529705A (en) * 1983-06-06 1985-07-16 Coulter Electronics, Inc. Reagent for combined diluting and lysing whole blood
US4751052A (en) * 1985-07-22 1988-06-14 Sequoia-Turner Corporation Tube alignment apparatus

Also Published As

Publication number Publication date
JPH06103299B2 (ja) 1994-12-14
DE3851433D1 (de) 1994-10-13
EP0353264B1 (de) 1994-09-07
CA1322325C (en) 1993-09-21
US4845025A (en) 1989-07-04
WO1989004484A1 (en) 1989-05-18
EP0353264A1 (de) 1990-02-07
EP0353264A4 (de) 1990-04-10
JPH02502126A (ja) 1990-07-12
ATE111223T1 (de) 1994-09-15

Similar Documents

Publication Publication Date Title
DE3851433T2 (de) Biologische probenmischvorrichtung und verfahren hierzu.
FI931602A (fi) Reagensapparatur och analysanordning i vilken den kan anvaendas
AU574169B2 (en) Sample processor using centrifugal force
ZA909204B (en) Apparatus for carrying out automatically in several successive steps an amino assay of at least one biologica substance in a plurality of biological samples,method an reagent using said apparatus
ES556608A0 (es) Un aparato para realizar un analisis
DE69322464D1 (de) Automatische Vorrichtung zur immunologischen Dosierung
ES446129A1 (es) Aparato para muestrear, mezclar y medir una muestra liquida.
DE3872361D1 (de) Analytisches reagenzmischungsgeraet zur ausfuehrung von aufeinanderfolgenden analytischen reaktionen.
DK0474607T3 (da) Apparat til diskontinuerlig on-line felt- eller procesanalyse til kolometrisk, kemisk monitorering af væskeprøver
DE69622935D1 (de) Halter für flachen Probenträger mit verminderter Z-Achsenveränderlichkeit
FR2458074A3 (fr) Recipients a echantillons ou a reactifs pour appareils d'analyse
ATE107910T1 (de) Vorrichtung zum mischen von jeweils zwei flüssigkeiten.
DE59106312D1 (de) Vorrichtung zum Nachweis markierter Mineralöle.
JPS5935870U (ja) 自動生化学分析装置

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee