DE4412190A1 - Prevention of snoring - Google Patents

Prevention of snoring

Info

Publication number
DE4412190A1
DE4412190A1 DE19944412190 DE4412190A DE4412190A1 DE 4412190 A1 DE4412190 A1 DE 4412190A1 DE 19944412190 DE19944412190 DE 19944412190 DE 4412190 A DE4412190 A DE 4412190A DE 4412190 A1 DE4412190 A1 DE 4412190A1
Authority
DE
Germany
Prior art keywords
substance
rhenchodepressive
injected
collagen
cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19944412190
Other languages
German (de)
Inventor
Hans Dr Dr Schreiber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SCHREIBER, HANS, DR. DR., 69469 WEINHEIM, DE
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19944412190 priority Critical patent/DE4412190A1/en
Publication of DE4412190A1 publication Critical patent/DE4412190A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Abstract

Prevention of rhenchopathy (snoring) comprises injecting a biocompatible substance, esp. a biological substance, into or around the velum in order to tighten the tissue. The biocompatible substance is pref. a cross-linked collagen or a substance having a similar activity.

Description

Die Rhenchopathie oder in der Umgangssprache das Schnarchen ist eine Form der Belästigung des sozialen Umfeldes, das oft zu familiären Spannungen führt.Rhenchopathy or colloquially snoring is a form of Harassment of the social environment, which often leads to family tensions.

Sie oder es tritt überwiegend in Schlafrückenlage auf und ist durch Schwingungen oder Flattern des weichen Gaumensegels, auch Velum genannt, bedingt. Das Zurückfallen der Zunge, die Behinderung der Nasenatmung und andere Faktoren sind zusätzlich zu benennen. Eine besondere pathologische Form stellt die Rhenchopathie in Kombination mit der sog. Schlafapnoe dar, bei der es zum kurzfristigen Atemstillstand kommt.She or it occurs mostly in the supine position and is due to vibrations or flutter of the soft palate sail, also called velum, conditionally. The Tongue falling back, obstruction of nasal breathing and other factors must also be named. The has a special pathological form Rhenchopathy in combination with the so-called sleep apnea, in which it is for short-term respiratory arrest comes.

Als Gegenmaßnahmen werden v. a. eine Verhinderung der Rückenlage und in Extremfällen eine straffend Gaumensegelplastik empfohlen.As countermeasures v. a. a prevention of supine and in In extreme cases, a firming soft palate is recommended.

Nun ist seit einigen Jahren in der plastischen Chirurgie als Alternative zum Skalpell bei Narbenkorrekturen die gezielte Injektion von Rindercollagen bekannt, das allerdings einen hohen Grad an früher Resorption aufweist.For several years now plastic surgery has been an alternative to the scalpel for scar corrections, the targeted injection of bovine collagen is known however, shows a high degree of early absorption.

Fibrilläres Collagen besteht aus sich wiederholenden Polypeptid-Untereinheiten, genannt Tropocollagen. Diese sind zu parallelen Bündeln angeordnet und weisen eine charakteristische 64-nm lange Querstreifung zumindest bei den meisten Collagenen auf.Fibrillar collagen consists of repeating polypeptide subunits, called tropocollagen. These are arranged in parallel bundles and point a characteristic 64 nm long striation, at least for most Collagens on.

Es besteht die Möglichkeit, über den Chemismus Collagen mit seinem ungewöhnlich hohen Anteil von Prolin- und Hydroxyprolinresten zusätzlich kovalent quer zu vernetzen.There is a possibility of collagen with his chemism unusually high proportion of proline and hydroxyproline residues cross-linking covalently.

Im Falle der kosmetischen Applikation ist damit die Möglichkeit geschaffen, das Collagen nicht nur subcutan zu injizieren und die Resorption zu verzögern.In the case of cosmetic application, this creates the possibility that Do not just inject collagen subcutaneously and delay absorption.

Aus diesem Grundgedanken heraus entstand der erfinderische Gedanke, quervernetztes Collagen, bevorzugt mit biologischen und/oder bioaktiven Füllstoffen ins Velum zu applizieren, um auf diesem Wege eine angestrebte Velumstraffung ohne phonetische Beeinträchtigungen zu schaffen.Based on this basic idea, the inventive idea arose cross-linked collagen, preferably with biological and / or bioactive Apply fillers in the velum in order to achieve a desired Velum tightening without creating phonetic impairments.

Wirkstoff und Anwendung sind in Verbindung mit der Beschreibung den Ansprüchen zu entnehmen.Active ingredient and application are in connection with the description Claims.

Claims (9)

1. Verfahren zur Anwendung rhenchodepressiver Substanzen, dadurch gekennzeichnet, daß biokompatibles, besser biologisches Material ins bzw. um das weiche Gaumensegel injiziert wird, um dessen Straffung bei Indikation der Rhenchopathie zu bewirken.1. A method for the use of rhenchodepressive substances, characterized in that biocompatible, better biological material is injected into or around the soft soft palate to effect its tightening when rhenchopathy is indicated. 2. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß die Substanz nach Verträglichkeitstestung angewandt wird.2. The method according to claim 1, characterized, that the substance is used after compatibility testing. 3. Verfahren nach mindestens einem der Ansprüche 1, 2, dadurch gekennzeichnet, daß bevorzugt die Substanz sukzessive und beginnend mit kleinen Dosen unter Beachtung der Stimmveränderung injiziert wird.3. The method according to at least one of claims 1, 2, characterized in that the substance is successively and starting with small doses considering the Voice change is injected. 4. Verfahren nach mindestens einem der Ansprüche 1-3, dadurch gekennzeichnet, daß die Substanz nach Grenzresorption nachinjiziert wird.4. The method according to at least one of claims 1-3, characterized, that the substance is re-injected after border absorption. 5. Verfahren nach mindestens einem der Ansprüche 1-4, dadurch gekennzeichnet, daß bevorzugt mit inerten oder bioaktiven Füllkörpern quervernetztes Collagen seitlich und/oder um die Umgebung des Frenulums injiziert wird.5. The method according to at least one of claims 1-4, characterized, that preferred with inert or bioactive packing cross-linked collagen on the side and / or around the surroundings of the frenulum is injected. 6. Verfahren nach mindestens einem der Ansprüche 1-5, dadurch gekennzeichnet, daß das Ende der Rhenchopathie das Ende des vorläufigen therapeutischen Vorgehens bedeutet. 6. The method according to at least one of claims 1-5, characterized, that the end of rhenchopathy is the end of the provisional therapeutic approach means.   7. Rhenchodepressive Substanz nach Anspruch 1, dadurch gekennzeichnet, daß diese als Grundgerüst ein quervernetztes Collagen oder eine bioverträgliche Substanz gleicher Wirkung aufweist.7. Rhenchodepressive substance according to claim 1, characterized, that this is a cross-linked collagen as the basic structure or has a biocompatible substance with the same effect. 8. Rhenchodepressive Substanz nach Anspruch 1, 7, dadurch gekennzeichnet, daß miniaturisierte, bevorzugt bioaktive Füllkörper in das quervernetzte Collagen passiv und/oder über chemische Bindung aktiv ins Collagen oder die Substanz gleicher Wirkung eingelagert sind.8. Rhenchodepressive substance according to claim 1, 7, characterized, that miniaturized, preferably bioactive filler in the cross-linked Passive and / or active chemical collagen into collagen or the substance with the same effect are stored. 9. Rhenchodepressive Substanz nach mindestens einem der Ansprüche 1, 7, 8, dadurch gekennzeichnet, daß diese bei korrekter Anwendung zu einem Straffungseffekt des Velums geführt hat, ohne negative phonetische Auswirkungen bewirkt zu haben.9. Rhenchodepressive substance according to at least one of claims 1, 7, 8, characterized, that, when used correctly, results in a tightening effect of the velum without negative phonetic effects to have brought about.
DE19944412190 1994-04-08 1994-04-08 Prevention of snoring Withdrawn DE4412190A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19944412190 DE4412190A1 (en) 1994-04-08 1994-04-08 Prevention of snoring

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19944412190 DE4412190A1 (en) 1994-04-08 1994-04-08 Prevention of snoring

Publications (1)

Publication Number Publication Date
DE4412190A1 true DE4412190A1 (en) 1995-10-12

Family

ID=6514958

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19944412190 Withdrawn DE4412190A1 (en) 1994-04-08 1994-04-08 Prevention of snoring

Country Status (1)

Country Link
DE (1) DE4412190A1 (en)

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6742524B2 (en) 2000-08-10 2004-06-01 Restore Medical, Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
JP2004154583A (en) * 1999-09-17 2004-06-03 Restore Medical Inc Medical treatment implant for respirator tract condition
US6848447B2 (en) 1999-09-17 2005-02-01 Restore Medical, Inc. Braided implant for snoring treatment
US7017582B2 (en) 2002-02-04 2006-03-28 Restore Medical Inc. Stiffening pharyngeal wall treatment
US7063089B2 (en) 1999-09-17 2006-06-20 Restore Medical Inc. Airway stiffening implant
US7107992B2 (en) 2002-10-04 2006-09-19 Pavad Medical, Inc. System and method for preventing closure of passageways
US7146981B2 (en) 2002-02-04 2006-12-12 Restore Medical, Inc. Pharyngeal wall treatment
US7213599B2 (en) 2003-10-31 2007-05-08 Restore Medical, Inc. Airway implant
JP2007512090A (en) * 2003-11-20 2007-05-17 アプネオン，インコーポレイテッド Device, system and method for anchoring tissue in a body region such as a pharyngeal conduit
US7237553B2 (en) 1999-09-17 2007-07-03 Restore Medical, Inc. Needle with pre-loaded implant for snoring treatment
US7237554B2 (en) 2003-10-31 2007-07-03 Restore Medical, Inc. Airway implant
US7322356B2 (en) 2005-02-24 2008-01-29 Restore Medical, Inc. Combination sleep apnea treatment
WO2008097890A2 (en) * 2007-02-02 2008-08-14 Thomas Jefferson University Method and use of a bioreplaceable tissue material implant for treating snoring
US7836888B2 (en) 2004-09-21 2010-11-23 Pavad Medical, Incorporated Airway implant and methods of making and using
US7882842B2 (en) 2004-09-21 2011-02-08 Pavad Medical, Inc. Airway implant sensors and methods of making and using the same
US20130087155A1 (en) * 2001-08-31 2013-04-11 Orthopeutics, L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US8578937B2 (en) 2004-09-21 2013-11-12 Medtronic Xomed, Inc. Smart mandibular repositioning system
US9445936B2 (en) 2011-02-04 2016-09-20 Joseph E. Kovarik Method of treating snoring and obstructive sleep apnea
US9492592B2 (en) 2007-02-28 2016-11-15 Orthopeutics, L. P. Crosslinker enhanced repair of knee meniscus
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11969445B2 (en) 2023-08-11 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH

Cited By (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7100613B2 (en) 1999-09-17 2006-09-05 Restore Medical Inc. Braided implant for snoring treatment
JP2004154583A (en) * 1999-09-17 2004-06-03 Restore Medical Inc Medical treatment implant for respirator tract condition
US6848447B2 (en) 1999-09-17 2005-02-01 Restore Medical, Inc. Braided implant for snoring treatment
JP4699690B2 (en) * 1999-09-17 2011-06-15 メドトロニック ゾメド， インコーポレイテッド Implants for the treatment of airway conditions
US7255109B2 (en) 1999-09-17 2007-08-14 Restore Medical, Inc. Polymer palate implant
US7028691B2 (en) 1999-09-17 2006-04-18 Restore Medical Inc. Braided implant for snoring treatment
US7036515B2 (en) 1999-09-17 2006-05-02 Restore Medical Inc. Braided implant for snoring treatment
US7047979B2 (en) 1999-09-17 2006-05-23 Restore Medical Inc. Soft palate implant with fiber construction
US7063089B2 (en) 1999-09-17 2006-06-20 Restore Medical Inc. Airway stiffening implant
US7237553B2 (en) 1999-09-17 2007-07-03 Restore Medical, Inc. Needle with pre-loaded implant for snoring treatment
US6971396B2 (en) 2000-08-10 2005-12-06 Restore Medical Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US7077143B2 (en) 2000-08-10 2006-07-18 Restore Medical Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US7255110B2 (en) 2000-08-10 2007-08-14 Restore Medical, Inc. Injection sleep apnea treatment
US6742524B2 (en) 2000-08-10 2004-06-01 Restore Medical, Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US7077144B2 (en) 2000-08-10 2006-07-18 Restore Medical Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US9918870B2 (en) * 2001-08-31 2018-03-20 Orthopeutics, L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US20130087155A1 (en) * 2001-08-31 2013-04-11 Orthopeutics, L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US9192507B2 (en) * 2001-08-31 2015-11-24 Orthopeutics, L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US20160015555A1 (en) * 2001-08-31 2016-01-21 Orthopeutcs. L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US7686021B2 (en) 2002-02-04 2010-03-30 Medtronic Xomed, Inc. Pharyngeal tissue stabilization
US7017582B2 (en) 2002-02-04 2006-03-28 Restore Medical Inc. Stiffening pharyngeal wall treatment
US7322993B2 (en) 2002-02-04 2008-01-29 Restore Medical Inc. Stiffening pharyngeal wall treatment
US7146981B2 (en) 2002-02-04 2006-12-12 Restore Medical, Inc. Pharyngeal wall treatment
US8864788B2 (en) 2002-02-04 2014-10-21 Medtronic Xomed, Inc. Pharyngeal wall treatment
US8430900B2 (en) 2002-02-04 2013-04-30 Medtronic Xomed, Inc. Pharyngeal wall treatment
US7669603B2 (en) 2002-02-04 2010-03-02 Medtronic Xomed, Inc. Pharyngeal wall treatment
US8424531B2 (en) 2002-02-04 2013-04-23 Medtronic Xomed, Inc. Pharyngeal wall treatment
US8413662B2 (en) 2002-02-04 2013-04-09 Medtronic Xomed, Inc. Stiffening pharyngeal wall treatment
US8037885B2 (en) 2002-02-04 2011-10-18 Restore Medical, Inc. Treatment for sleep apnea or snoring
US7107992B2 (en) 2002-10-04 2006-09-19 Pavad Medical, Inc. System and method for preventing closure of passageways
US7401611B2 (en) 2003-10-31 2008-07-22 Restore Medical, Inc. Airway implant
US7703460B2 (en) 2003-10-31 2010-04-27 Medtronic Xomed, Inc. Tongue implant
US7237554B2 (en) 2003-10-31 2007-07-03 Restore Medical, Inc. Airway implant
US7213599B2 (en) 2003-10-31 2007-05-08 Restore Medical, Inc. Airway implant
US7673635B2 (en) 2003-10-31 2010-03-09 Medtronix Xomed, Inc. Soft palate implant
JP2007512090A (en) * 2003-11-20 2007-05-17 アプネオン，インコーポレイテッド Device, system and method for anchoring tissue in a body region such as a pharyngeal conduit
US7882842B2 (en) 2004-09-21 2011-02-08 Pavad Medical, Inc. Airway implant sensors and methods of making and using the same
US8578937B2 (en) 2004-09-21 2013-11-12 Medtronic Xomed, Inc. Smart mandibular repositioning system
US7836888B2 (en) 2004-09-21 2010-11-23 Pavad Medical, Incorporated Airway implant and methods of making and using
US7322356B2 (en) 2005-02-24 2008-01-29 Restore Medical, Inc. Combination sleep apnea treatment
WO2008097890A3 (en) * 2007-02-02 2009-09-17 Thomas Jefferson University Method and use of a bioreplaceable tissue material implant for treating snoring
WO2008097890A2 (en) * 2007-02-02 2008-08-14 Thomas Jefferson University Method and use of a bioreplaceable tissue material implant for treating snoring
US9492592B2 (en) 2007-02-28 2016-11-15 Orthopeutics, L. P. Crosslinker enhanced repair of knee meniscus
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US9445936B2 (en) 2011-02-04 2016-09-20 Joseph E. Kovarik Method of treating snoring and obstructive sleep apnea
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11969445B2 (en) 2023-08-11 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH

Similar Documents

Publication Publication Date Title
DE4412190A1 (en) Prevention of snoring
Ford et al. Clinical experience with injectable collagen for vocal fold augmentation
DE3713539C2 (en) SYNERGETIC RAILING FOR THE EARLY MOBILIZATION OF THE HAND BEND TENSIONS
ATE96678T1 (en) METHOD OF REDUCING SKIN IRRITATION WHEN USING PERFORMANCE-ENHANCED MEDICINAL COMPOSITIONS.
DE60128449T2 (en) SYSTEM FOR THE CONTROLLED DELIVERY OF ACTIVE MATERIALS TO A TOOTH SURFACE
DE69027865D1 (en) COMPOSITIONS containing omega conotoxin peptide derivatives and their use for the treatment of ischemic-like neuronal damage
DE69218948D1 (en) IGF-I to improve the neuronal position
DE69533112T2 (en) USE OF FLAVOLIGNANES FOR THE PRODUCTION OF MEDICINES WITH ANTIPROLIFERATIVE ACTIVITY IN UTERUS, BREAST, EGGS
DE2950219A1 (en) IMPLANTED ARTIFICIAL TOOTH
DE69507112T2 (en) Use of a serotonin agonist in combination with a tachykinin receptor antagonist for the manufacture of a medicament for the prevention or treatment of migraines
ATE141505T1 (en) USE OF 3-GUANIDINOPROPIONIC ACID FOR THE PRODUCTION OF A MEDICATION FOR THE TREATMENT AND PREVENTION OF OBESITY
EP3585324B1 (en) Nail correction kit
WO2003026489A3 (en) Biopolymer and biopolymer-cell compositions for nerve tissue repair
DE3233419A1 (en) Toenail appliance
DE4434459A1 (en) Barrier layer to control tissue growth
DE4207797A1 (en) Device for correcting in-growing toe-nails - consists of two wire hooks which grip edges of toe-nail
DE69326122D1 (en) USE OF IGF-II GROWTH FACTOR TO TREAT GASTROINTESTINAL DISORDERS
DE69733169D1 (en) Use of alpha 1 adrenoceptor antagonists for the manufacture of a medicament for the prevention and treatment of cancer
DE2743008A1 (en) PROCESS FOR MAKING A PRESERVED PLASTER IMPRESSION AND DEVICE FOR CARRYING OUT THE PROCESS
Irvine et al. The Entropien Patch: A Method of Temporarily Correcting Involutional Entropion With Adhesive Tape
ATE143809T1 (en) PLACENTA EXTRACT AND METHOD FOR THE PRODUCTION THEREOF
CASSCELLS et al. Intramedullary-wire fixation of mallet finger
DE2123840A1 (en) Device for adjusting a lower leg prosthesis
DE19505804A1 (en) Prevention of snoring by sleeping person
DE370786C (en) Fixation-distraction device, especially for horses

Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: SCHREIBER, HANS, DR. DR., 69469 WEINHEIM, DE

8139 Disposal/non-payment of the annual fee