DE50011574D1 - Mikrofluidischer reaktionsträger mit drei strömungsebenen - Google Patents
Mikrofluidischer reaktionsträger mit drei strömungsebenenInfo
- Publication number
- DE50011574D1 DE50011574D1 DE50011574T DE50011574T DE50011574D1 DE 50011574 D1 DE50011574 D1 DE 50011574D1 DE 50011574 T DE50011574 T DE 50011574T DE 50011574 T DE50011574 T DE 50011574T DE 50011574 D1 DE50011574 D1 DE 50011574D1
- Authority
- DE
- Germany
- Prior art keywords
- channels
- carrier
- reaction
- reaction zones
- light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0874—Three dimensional network
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE50011574T DE50011574D1 (de) | 1999-08-01 | 2000-08-01 | Mikrofluidischer reaktionsträger mit drei strömungsebenen |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19935433A DE19935433A1 (de) | 1999-08-01 | 1999-08-01 | Mikrofluidischer Reaktionsträger |
DE50011574T DE50011574D1 (de) | 1999-08-01 | 2000-08-01 | Mikrofluidischer reaktionsträger mit drei strömungsebenen |
PCT/EP2000/007445 WO2001008799A1 (de) | 1999-08-01 | 2000-08-01 | Mikrofluidischer reaktionsträger mit drei strömungsebenen und transparenter deckschicht |
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DE50011574D1 true DE50011574D1 (de) | 2005-12-15 |
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DE19935433A Ceased DE19935433A1 (de) | 1999-08-01 | 1999-08-01 | Mikrofluidischer Reaktionsträger |
DE50011574T Expired - Lifetime DE50011574D1 (de) | 1999-08-01 | 2000-08-01 | Mikrofluidischer reaktionsträger mit drei strömungsebenen |
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DE19935433A Ceased DE19935433A1 (de) | 1999-08-01 | 1999-08-01 | Mikrofluidischer Reaktionsträger |
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US (2) | US7361314B1 (de) |
EP (2) | EP1198294B1 (de) |
AT (1) | ATE309041T1 (de) |
AU (1) | AU6569200A (de) |
CA (1) | CA2379787A1 (de) |
DE (2) | DE19935433A1 (de) |
WO (1) | WO2001008799A1 (de) |
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DE19935433A1 (de) * | 1999-08-01 | 2001-03-01 | Febit Ferrarius Biotech Gmbh | Mikrofluidischer Reaktionsträger |
DE19963594C2 (de) * | 1999-12-23 | 2002-06-27 | Mannesmann Ag | Vorrichtung in Mikrostrukturtechnik zum Hindurchleiten von Medien sowie Verwendung als Brennstoffzellensystem |
DE10041853C1 (de) * | 2000-08-25 | 2002-02-28 | Gmd Gmbh | Konfigurierbares Mikroreaktornetzwerk |
DE10062246C1 (de) * | 2000-12-14 | 2002-05-29 | Advalytix Ag | Verfahren und Vorrichtung zur Manipulation kleiner Flüssigkeitsmengen |
DE10102726A1 (de) * | 2001-01-22 | 2002-08-22 | Vodafone Pilotentwicklung Gmbh | Reaktor |
DE10115474A1 (de) * | 2001-03-29 | 2002-10-10 | Infineon Technologies Ag | Mikrofluidkanalstruktur und Verfahren zur Herstellung einer derartigen Mikrofluidkanalstruktur |
IL158487A0 (en) | 2001-05-18 | 2004-05-12 | Wisconsin Alumni Res Found | Method for the synthesis of dna sequences |
US20020187072A1 (en) * | 2001-06-07 | 2002-12-12 | Nanostream, Inc. | Multi-layer microfluidic splitter |
DE10142691B4 (de) * | 2001-08-31 | 2006-04-20 | Infineon Technologies Ag | Verfahren zum Nachweis biochemischer Reaktionen sowie eine Vorrichtung hierfür |
DE10143189A1 (de) * | 2001-09-04 | 2003-03-20 | Clariant Gmbh | Verfahren und Vorrichtung zur prozeßbegleitenden Reinigung von Mikro-und Minireaktoren |
DE10145831A1 (de) * | 2001-09-10 | 2003-04-03 | Siemens Ag | Verfahren zur Individualisierung von Materialien mit Hilfe von Nukleotid-Sequenzen |
DE10218280C1 (de) * | 2002-04-19 | 2003-11-20 | Fraunhofer Ges Forschung | Integriertes Misch- und Schaltsystem für die Mikroreaktionstechnik |
US7718099B2 (en) | 2002-04-25 | 2010-05-18 | Tosoh Corporation | Fine channel device, fine particle producing method and solvent extraction method |
FR2839660B1 (fr) * | 2002-05-17 | 2005-01-21 | Commissariat Energie Atomique | Microreacteur,son procede de preparation,et procede pour realiser une reaction biochimique ou biologique |
AU2003248273A1 (en) * | 2002-07-12 | 2004-02-02 | Mitsubishi Chemical Corporation | Analytical chip, analytical chip unit, analyzing apparatus, method of analysis using the apparatus, and method of producing the analytical chip |
WO2004010760A2 (en) * | 2002-07-26 | 2004-02-05 | Applera Corporation | Microfluidic size-exclusion devices, systems, and methods |
US7214348B2 (en) | 2002-07-26 | 2007-05-08 | Applera Corporation | Microfluidic size-exclusion devices, systems, and methods |
DE10341500A1 (de) * | 2003-09-05 | 2005-03-31 | Ehrfeld Mikrotechnik Ag | Mikrophotoreaktor zur Durchführung photochemischer Reaktionen |
US7422910B2 (en) * | 2003-10-27 | 2008-09-09 | Velocys | Manifold designs, and flow control in multichannel microchannel devices |
US7169617B2 (en) * | 2004-08-19 | 2007-01-30 | Fujitsu Limited | Device and method for quantitatively determining an analyte, a method for determining an effective size of a molecule, a method for attaching molecules to a substrate, and a device for detecting molecules |
US8252245B2 (en) | 2004-11-03 | 2012-08-28 | Velocys, Inc. | Partial boiling in mini and micro-channels |
US7641865B2 (en) | 2005-04-08 | 2010-01-05 | Velocys | Flow control through plural, parallel connecting channels to/from a manifold |
WO2007033385A2 (en) * | 2005-09-13 | 2007-03-22 | Fluidigm Corporation | Microfluidic assay devices and methods |
DE102006024355B4 (de) * | 2006-05-19 | 2008-04-03 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Mikrofluidische Anordnung zur Detektion von in Proben enthaltenen chemischen, biochemischen Molekülen und/oder Partikeln |
DE102007018833A1 (de) | 2007-04-20 | 2008-10-23 | Febit Holding Gmbh | Verbesserte molekularbiologische Prozessanlage |
DE102006062089A1 (de) | 2006-12-29 | 2008-07-03 | Febit Holding Gmbh | Verbesserte molekularbiologische Prozessanlage |
EP1980854B1 (de) * | 2007-04-12 | 2009-10-07 | Micronas Holding GmbH | Verfahren und Vorrichtung zur Messung der Konzentration eines in einer zu untersuchenden Probe enthaltenen Liganden |
EP2556887A1 (de) * | 2011-08-08 | 2013-02-13 | SAW instruments GmbH | Verbesserte mikrofluidische Vorrichtungen zur selektiven Exposition von einer oder mehr Probeflüssigkeiten mit einem oder mehreren Probenbereichen |
CN105498867B (zh) * | 2014-09-22 | 2017-07-04 | 北京科技大学 | 梯度二氧化硅表面微流体系统的构筑方法 |
CN104991055A (zh) * | 2015-06-19 | 2015-10-21 | 大连理工大学 | 一种血栓即时检测poct产品中的血液样本延时流动仿生操控单元 |
DE102016222035A1 (de) | 2016-11-10 | 2018-05-17 | Robert Bosch Gmbh | Mikrofluidische Vorrichtung und Verfahren zur Analyse von Proben |
DE102022209420A1 (de) * | 2022-09-09 | 2024-03-14 | Robert Bosch Gesellschaft mit beschränkter Haftung | Array für eine mikrofluidische Vorrichtung, mikrofluidische Vorrichtung und Verfahren zu ihrem Betrieb. |
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EP0637997B1 (de) * | 1992-05-01 | 1998-07-01 | Trustees Of The University Of Pennsylvania | Analyse bei messung des durchflusswiderstandes |
US5534328A (en) * | 1993-12-02 | 1996-07-09 | E. I. Du Pont De Nemours And Company | Integrated chemical processing apparatus and processes for the preparation thereof |
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DE19745373A1 (de) * | 1997-10-14 | 1999-04-15 | Bayer Ag | Optisches Meßsystem zur Erfassung von Lumineszenz- oder Fluoreszenzsignalen |
EP1054735B1 (de) * | 1998-02-11 | 2003-05-28 | Institut Für Physikalische Hochtechnologie E.V. | Miniaturisierter temperaturzonen flussreaktor |
US6210910B1 (en) * | 1998-03-02 | 2001-04-03 | Trustees Of Tufts College | Optical fiber biosensor array comprising cell populations confined to microcavities |
IL138286A (en) * | 1998-03-11 | 2004-02-19 | Steag Micro Parts Gmbh | Sample support |
US6485690B1 (en) * | 1999-05-27 | 2002-11-26 | Orchid Biosciences, Inc. | Multiple fluid sample processor and system |
DE19935433A1 (de) * | 1999-08-01 | 2001-03-01 | Febit Ferrarius Biotech Gmbh | Mikrofluidischer Reaktionsträger |
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1999
- 1999-08-01 DE DE19935433A patent/DE19935433A1/de not_active Ceased
-
2000
- 2000-08-01 US US10/030,182 patent/US7361314B1/en not_active Expired - Fee Related
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- 2000-08-01 EP EP00953136A patent/EP1198294B1/de not_active Expired - Lifetime
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- 2000-08-01 DE DE50011574T patent/DE50011574D1/de not_active Expired - Lifetime
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DE19935433A1 (de) | 2001-03-01 |
ATE309041T1 (de) | 2005-11-15 |
US20080132430A1 (en) | 2008-06-05 |
WO2001008799A9 (de) | 2002-09-06 |
EP1198294A1 (de) | 2002-04-24 |
EP1652578A3 (de) | 2006-07-26 |
CA2379787A1 (en) | 2001-02-08 |
AU6569200A (en) | 2001-02-19 |
EP1198294B1 (de) | 2005-11-09 |
WO2001008799A1 (de) | 2001-02-08 |
US7361314B1 (en) | 2008-04-22 |
EP1652578A2 (de) | 2006-05-03 |
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