DE59712220D1 - Inositolglykane mit insulinartiger Wirkung - Google Patents

Inositolglykane mit insulinartiger Wirkung

Info

Publication number
DE59712220D1
DE59712220D1 DE59712220T DE59712220T DE59712220D1 DE 59712220 D1 DE59712220 D1 DE 59712220D1 DE 59712220 T DE59712220 T DE 59712220T DE 59712220 T DE59712220 T DE 59712220T DE 59712220 D1 DE59712220 D1 DE 59712220D1
Authority
DE
Germany
Prior art keywords
insulin
action
inositol glycans
glycans
inositol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE59712220T
Other languages
English (en)
Inventor
Dr Frick
Dr Mueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Aventis Pharma Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland GmbH filed Critical Aventis Pharma Deutschland GmbH
Priority to DE59712220T priority Critical patent/DE59712220D1/de
Application granted granted Critical
Publication of DE59712220D1 publication Critical patent/DE59712220D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04Disaccharides
DE59712220T 1996-11-28 1997-11-13 Inositolglykane mit insulinartiger Wirkung Expired - Fee Related DE59712220D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE59712220T DE59712220D1 (de) 1996-11-28 1997-11-13 Inositolglykane mit insulinartiger Wirkung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19649350A DE19649350A1 (de) 1996-11-28 1996-11-28 Inositolglykane mit insulinartiger Wirkung
DE59712220T DE59712220D1 (de) 1996-11-28 1997-11-13 Inositolglykane mit insulinartiger Wirkung

Publications (1)

Publication Number Publication Date
DE59712220D1 true DE59712220D1 (de) 2005-04-14

Family

ID=7813041

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19649350A Withdrawn DE19649350A1 (de) 1996-11-28 1996-11-28 Inositolglykane mit insulinartiger Wirkung
DE59712220T Expired - Fee Related DE59712220D1 (de) 1996-11-28 1997-11-13 Inositolglykane mit insulinartiger Wirkung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19649350A Withdrawn DE19649350A1 (de) 1996-11-28 1996-11-28 Inositolglykane mit insulinartiger Wirkung

Country Status (19)

Country Link
US (1) US6004938A (de)
EP (1) EP0845475B1 (de)
JP (1) JP4299378B2 (de)
CN (1) CN1136224C (de)
AR (1) AR018246A1 (de)
AT (1) ATE290541T1 (de)
AU (1) AU728637B2 (de)
BR (1) BR9706041C1 (de)
CA (1) CA2222103C (de)
CZ (1) CZ294886B6 (de)
DE (2) DE19649350A1 (de)
DK (1) DK0845475T3 (de)
ES (1) ES2237784T3 (de)
HK (1) HK1008786A1 (de)
HU (1) HUP9702242A3 (de)
PL (1) PL188604B1 (de)
PT (1) PT845475E (de)
RU (1) RU2178794C2 (de)
TR (1) TR199701432A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7312196B2 (en) * 1997-01-08 2007-12-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
GB9814039D0 (en) * 1998-06-29 1998-08-26 Univ London Materials and methods relating to the prevention or treatment of ischaemia-reperfusion injury
US6939857B2 (en) 2000-05-12 2005-09-06 Rodaris Pharmaceuticals Limited Compounds and their uses
US6759390B2 (en) 2000-05-12 2004-07-06 Manuel Martin-Lomas Compounds and their uses
US6716826B2 (en) 2000-05-12 2004-04-06 Rodaris Pharmaceuticals Limited Compounds and their uses
EP1406913A2 (de) * 2000-05-12 2004-04-14 Rodaris Pharmaceuticals Limited Inositolglycane und ihre verwendung
ATE388161T1 (de) * 2000-05-12 2008-03-15 Rodaris Pharmaceuticals Ltd Inositolphosphoglycanderivate und ihre medizinische verwendung
AU2001254979A1 (en) * 2000-05-12 2001-11-20 Rodaris Pharmaceuticals Limited Inositol phosphoglycan derivatives and their medical uses
US6953781B2 (en) 2000-05-12 2005-10-11 Rodaris Pharmaceuticals Limited Compounds and their uses
GB0015627D0 (en) * 2000-06-26 2000-08-16 Rademacher Group Limited Phosphoglycan messengers and their medical uses
FR2828206B1 (fr) * 2001-08-03 2004-09-24 Centre Nat Rech Scient Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
AU2003231157C1 (en) 2002-04-29 2009-02-26 Normoxys, Inc. Inositol pyrophosphates, and methods of use thereof
EP1542703A4 (de) * 2002-07-10 2007-11-07 Massachusetts Inst Technology Festphasen- und l sungsphasen-synthese von glycosylphosphatidylinositol-glykanen
CN100369610C (zh) * 2002-10-09 2008-02-20 中国药科大学 一种防治糖尿病的植物提取物及其制备方法与药物用途
US20070135389A1 (en) * 2004-07-06 2007-06-14 Claude Nicolau Tumor eradication by inositol-tripyrophosphate
US20060106000A1 (en) * 2004-07-06 2006-05-18 Claude Nicolau Use of inositol-tripyrophosphate in treating tumors and diseases
US7745423B2 (en) * 2004-07-06 2010-06-29 NormOxys, Inc Calcium/sodium salt of inositol tripyrophosphate as an allosteric effector of hemoglobin
FR2878850B1 (fr) * 2004-12-02 2008-10-31 Cis Bio Internat Sa Derives de l'inositol-1-phosphate
US20100197625A1 (en) * 2006-12-21 2010-08-05 D Alarcao Marc Synthetic lipophilic inositol glycans for treatment of cancer and glucose-metabolism disorders
CN101686986A (zh) * 2006-12-29 2010-03-31 诺尔姆奥克西斯公司 环多醇和其衍生物及其治疗应用
CN101784193A (zh) * 2007-05-01 2010-07-21 诺尔姆奥克西斯公司 促红细胞生成素互补或替代

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446064A (en) * 1980-12-19 1984-05-01 The University Of Virginia Alumni Patents Foundation Insulin mediator substance
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
US4906468A (en) * 1986-04-11 1990-03-06 The Rockefeller University Insulin activity messengers, their antibodies, and thereof
YU66892A (sh) * 1991-08-20 1995-10-24 Hoechst Ag. Fosfoinositolglikan - peptid sa delovanjem kao insulin
ES2137937T3 (es) * 1991-11-29 2000-01-01 Hoechst Ag Peptidos con efecto del tipo de insulina.
JPH06293790A (ja) * 1993-04-08 1994-10-21 Kyowa Hakko Kogyo Co Ltd 生理活性物質イノシトールグリカン
US5652221A (en) * 1994-11-07 1997-07-29 The University Of Virginia Patent Foundation Method of treating defective glucose metabolism using synthetic insulin substances

Also Published As

Publication number Publication date
HUP9702242A1 (hu) 1998-12-28
AU4538297A (en) 1998-06-04
TR199701432A2 (xx) 1998-06-22
BR9706041A (pt) 1999-11-23
MX9709207A (es) 1998-05-31
CN1184112A (zh) 1998-06-10
JP4299378B2 (ja) 2009-07-22
CZ377597A3 (cs) 1998-06-17
CZ294886B6 (cs) 2005-04-13
AR018246A1 (es) 2001-11-14
PL188604B1 (pl) 2005-03-31
DE19649350A1 (de) 1998-06-04
HK1008786A1 (en) 1999-05-21
HU9702242D0 (en) 1998-03-02
US6004938A (en) 1999-12-21
PT845475E (pt) 2005-06-30
ATE290541T1 (de) 2005-03-15
CN1136224C (zh) 2004-01-28
EP0845475A1 (de) 1998-06-03
CA2222103A1 (en) 1998-05-28
DK0845475T3 (da) 2005-06-27
PL323407A1 (en) 1998-06-08
JPH10158291A (ja) 1998-06-16
ES2237784T3 (es) 2005-08-01
CA2222103C (en) 2007-08-28
EP0845475B1 (de) 2005-03-09
BR9706041C1 (pt) 2000-06-06
AU728637B2 (en) 2001-01-11
HUP9702242A3 (en) 1999-01-28
RU2178794C2 (ru) 2002-01-27

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, 65929 FRANKFURT,

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee