DE60010072D1 - Stereokomplexe hydrogele - Google Patents

Stereokomplexe hydrogele

Info

Publication number
DE60010072D1
DE60010072D1 DE60010072T DE60010072T DE60010072D1 DE 60010072 D1 DE60010072 D1 DE 60010072D1 DE 60010072 T DE60010072 T DE 60010072T DE 60010072 T DE60010072 T DE 60010072T DE 60010072 D1 DE60010072 D1 DE 60010072D1
Authority
DE
Germany
Prior art keywords
interaction
hydrogels
stereo complex
chirality
hydrogel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60010072T
Other languages
English (en)
Other versions
DE60010072T2 (de
Inventor
Everhardus Hennink
Nostrum Franciscus Van
Jong Johanna De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UNIVERSITEIT UTRECHT UTRECHT
Original Assignee
UNIVERSITEIT UTRECHT UTRECHT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNIVERSITEIT UTRECHT UTRECHT filed Critical UNIVERSITEIT UTRECHT UTRECHT
Publication of DE60010072D1 publication Critical patent/DE60010072D1/de
Application granted granted Critical
Publication of DE60010072T2 publication Critical patent/DE60010072T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/12—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity
    • C08L101/14—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
DE60010072T 1999-02-19 2000-02-21 Stereokomplexe hydrogele Expired - Lifetime DE60010072T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99200472 1999-02-19
EP99200472 1999-02-19
PCT/NL2000/000108 WO2000048576A1 (en) 1999-02-19 2000-02-21 Stereocomplex hydrogels

Publications (2)

Publication Number Publication Date
DE60010072D1 true DE60010072D1 (de) 2004-05-27
DE60010072T2 DE60010072T2 (de) 2005-03-24

Family

ID=8239899

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60010072T Expired - Lifetime DE60010072T2 (de) 1999-02-19 2000-02-21 Stereokomplexe hydrogele

Country Status (9)

Country Link
US (2) US7776359B1 (de)
EP (1) EP1183016B1 (de)
JP (1) JP4865947B2 (de)
AT (1) ATE264669T1 (de)
AU (1) AU2831900A (de)
DE (1) DE60010072T2 (de)
DK (1) DK1183016T3 (de)
ES (1) ES2220406T3 (de)
WO (1) WO2000048576A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2445523A1 (en) 2001-04-30 2002-11-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Composite scaffolds and methods using same for generating complex tissue grafts
JP2006175153A (ja) * 2004-12-24 2006-07-06 Goodman Co Ltd 医療用生分解性生体吸収材料
WO2004078197A1 (en) * 2003-03-04 2004-09-16 The Technology Development Company Ltd. Delivery system for drug and cell therapy
JP4459543B2 (ja) * 2003-03-17 2010-04-28 株式会社メドジェル 徐放性ハイドロゲル製剤
WO2005054318A1 (en) * 2003-12-04 2005-06-16 Universiteit Utrecht Stereocomplex hydrogels with tunable degradation times
EP1576952A1 (de) * 2004-03-18 2005-09-21 OctoPlus Technologies B.V. Hydrogel-Mikrosphären mit verbessertem Freisetzungsprofil
EP1595534A1 (de) * 2004-05-13 2005-11-16 Universiteit Utrecht Holding B.V. Gelzusammensetzung enthaltend geladenepolymere
EP1891941A1 (de) * 2006-08-11 2008-02-27 OctoPlus Technologies B.V. Wässrige Gele enthaltend Mikrokügelchen
ATE524504T1 (de) * 2007-03-20 2011-09-15 Univ Twente Stereophotohydrogel, verfahren zur herstellung des stereophotohydrogels, polymere zur verwendung bei der herstellung eines derartigen hydrogels und pharmazeutikum, das die polymere enthält
WO2011129772A1 (en) * 2010-04-14 2011-10-20 Agency For Science, Technology And Research Elastomers crosslinked by polylactic acid
JP5615373B2 (ja) * 2010-09-14 2014-10-29 国立大学法人大阪大学 分子認識に基づいた物質材料の選択的接着法および自己組織化法
FR2966248B1 (fr) * 2010-10-18 2020-05-01 Centre National De La Recherche Scientifique (Cnrs) Procede de fonctionnalisation de surfaces pour la detection d'analytes
US8709466B2 (en) 2011-03-31 2014-04-29 International Business Machines Corporation Cationic polymers for antimicrobial applications and delivery of bioactive materials
US8642086B2 (en) 2011-03-31 2014-02-04 International Business Machines Corporation Antimicrobial compositions, methods of preparation thereof, and uses thereof
NL1039667C2 (en) * 2012-06-11 2013-12-12 Purac Biochem Bv Quantification of lactide amounts in a polymeric matrix.
ES2658972T3 (es) * 2012-06-20 2018-03-13 University Of Waterloo Sistema de administración de nanopartículas mucoadhesivas
US9878000B2 (en) 2012-06-20 2018-01-30 University Of Waterloo Mucoadhesive nanoparticle composition comprising immunosuppresant and methods of use thereof
CN103816841B (zh) * 2013-12-05 2015-08-26 江南大学 一种具有等离子体手性的水凝胶的制备方法
CN104940995B (zh) * 2015-06-29 2017-04-12 哈尔滨工业大学 一种以牛血清白蛋白为基元反相微乳液制备蛋白质水凝胶微球的方法
EP3482964A1 (de) * 2017-11-13 2019-05-15 Mitsubishi HiTec Paper Europe GmbH Wärmeempfindliches aufzeichnungsmaterial auf basis von pla
CN109316632B (zh) * 2018-11-15 2021-04-20 北京大学口腔医学院 使用左旋水凝胶材料促进骨髓间充质干细胞成骨分化的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE37983T1 (de) 1982-04-22 1988-11-15 Ici Plc Mittel mit verzoegerter freigabe.
GB8319766D0 (en) * 1983-07-22 1983-08-24 Graham N B Controlled release device
US4650488A (en) * 1984-05-16 1987-03-17 Richards Medical Company Biodegradable prosthetic device
JPS6136321A (ja) 1984-07-27 1986-02-21 Daicel Chem Ind Ltd 新規なポリマ−およびその樹脂組成物
US4788979A (en) * 1986-09-23 1988-12-06 American Cyanamid Company Bioabsorbable coating for a surgical article
US4902515A (en) 1988-04-28 1990-02-20 E. I. Dupont De Nemours And Company Polylactide compositions
US5230900A (en) * 1988-07-01 1993-07-27 The Biomembrane Institute Antibody-mediated and ligand-mediated targeting of differentiation-inducers to tumor cells
DK0910412T3 (da) 1996-07-01 2003-08-11 Univ Utrecht Hydrolyserbare hydrogeler til kontrolleret frigørelse
IL122933A (en) * 1998-01-14 2005-03-20 Efrat Biopolymers Ltd Polymeric carrier for delivery of a bioactive molecule
JPH11269097A (ja) 1998-01-20 1999-10-05 Takeda Chem Ind Ltd 新規な微粒子、その製造法および用途
JP3687354B2 (ja) 1998-06-30 2005-08-24 トヨタ自動車株式会社 ポリ乳酸ステレオコンプレックスポリマー組成物
US7049357B2 (en) * 2001-04-23 2006-05-23 The Glidden Company Odor free polylactic acid modified aqueous emulsion paints free of volatile coalescing organic solvent

Also Published As

Publication number Publication date
EP1183016B1 (de) 2004-04-21
AU2831900A (en) 2000-09-04
ATE264669T1 (de) 2004-05-15
US7776359B1 (en) 2010-08-17
US20100255098A1 (en) 2010-10-07
DK1183016T3 (da) 2004-08-09
WO2000048576A1 (en) 2000-08-24
DE60010072T2 (de) 2005-03-24
JP4865947B2 (ja) 2012-02-01
JP2002537416A (ja) 2002-11-05
ES2220406T3 (es) 2004-12-16
EP1183016A1 (de) 2002-03-06

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