DE60014028D1 - Funktionalisierte verbindung, gegebenenfalls markierte polynukleotide und verfahren zur detektion einer ziel-nukleinsäure - Google Patents

Funktionalisierte verbindung, gegebenenfalls markierte polynukleotide und verfahren zur detektion einer ziel-nukleinsäure

Info

Publication number
DE60014028D1
DE60014028D1 DE60014028T DE60014028T DE60014028D1 DE 60014028 D1 DE60014028 D1 DE 60014028D1 DE 60014028 T DE60014028 T DE 60014028T DE 60014028 T DE60014028 T DE 60014028T DE 60014028 D1 DE60014028 D1 DE 60014028D1
Authority
DE
Germany
Prior art keywords
detecting
nucleic acid
target nucleic
polynucleotids
marked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60014028T
Other languages
English (en)
Other versions
DE60014028T2 (de
Inventor
Eric Defranc
Ali Laayoun
Jean Lhomme
Emmanuelle Trevisiol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA filed Critical Biomerieux SA
Publication of DE60014028D1 publication Critical patent/DE60014028D1/de
Application granted granted Critical
Publication of DE60014028T2 publication Critical patent/DE60014028T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
DE60014028T 1999-01-05 2000-01-05 Funktionalisierte verbindung, gegebenenfalls markierte polynukleotide und verfahren zur detektion einer zielnukleinsäure Expired - Lifetime DE60014028T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9900111 1999-01-05
FR9900111 1999-01-05
PCT/FR2000/000011 WO2000040590A2 (fr) 1999-01-05 2000-01-05 Compose fonctionnalise, polynucleotide eventuellement marque et procede de detection d'un acide nucleique cible

Publications (2)

Publication Number Publication Date
DE60014028D1 true DE60014028D1 (de) 2004-10-28
DE60014028T2 DE60014028T2 (de) 2006-03-02

Family

ID=9540687

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60014028T Expired - Lifetime DE60014028T2 (de) 1999-01-05 2000-01-05 Funktionalisierte verbindung, gegebenenfalls markierte polynukleotide und verfahren zur detektion einer zielnukleinsäure

Country Status (7)

Country Link
US (1) US6875858B1 (de)
EP (1) EP1140963B1 (de)
AT (1) ATE277065T1 (de)
AU (1) AU3050800A (de)
CA (1) CA2357793A1 (de)
DE (1) DE60014028T2 (de)
WO (1) WO2000040590A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7102024B1 (en) 2000-08-01 2006-09-05 Schwartz David A Functional biopolymer modification reagents and uses thereof
US6686461B1 (en) 2000-03-22 2004-02-03 Solulink Bioscience, Inc. Triphosphate oligonucleotide modification reagents and uses thereof
EP1315699B1 (de) 2000-03-22 2013-01-02 Solulink, Incorporated Hydrazin- und carbonyl-basierte bifunktionelle vernetzungsmittel
US7060441B2 (en) 2001-05-04 2006-06-13 Biomerieux Method for fragmenting and labeling DNA involving abasic sites and phosphate labeling
US7338805B2 (en) 2001-05-04 2008-03-04 Bio Merieux Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules
US7803536B2 (en) * 2002-09-20 2010-09-28 Integrated Dna Technologies, Inc. Methods of detecting fluorescence with anthraquinone quencher dyes
WO2005049849A2 (en) 2003-11-14 2005-06-02 Integrated Dna Technologies, Inc. Fluorescence quenching azo dyes, their methods of preparation and use
FR2868071B1 (fr) 2004-03-26 2006-06-09 Biomerieux Sa Reactifs de marquage, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
US20080026381A1 (en) * 2006-07-31 2008-01-31 Siddiqi Suhaib M Nucleotide analogs
CA2601554A1 (en) 2005-05-20 2006-11-30 Integrated Dna Technologies, Inc. Compounds and methods for labeling oligonucleotides
FR2886735B1 (fr) 2005-06-01 2015-09-11 Biomerieux Sa Procede de marquage ou de traitement d'un echantillon biologique contenant des molecules biologiques d'interet, notamment des acides nucleiques
FR2917090B1 (fr) 2007-06-11 2012-06-15 Biomerieux Sa Reactifs de marquage portant des fonctions diazo et nitro, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
WO2009006446A2 (en) * 2007-06-28 2009-01-08 Integrated Dna Technologies, Inc. Methods for cloning small rna species
FR2934595B1 (fr) 2008-07-29 2013-04-05 Biomerieux Sa Reactifs de marquage ayant un noyau pyridine portant une fonction diazomethyle, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
US20120108799A1 (en) 2010-09-07 2012-05-03 Integrated Dna Technologies, Inc. Modifications for Antisense Compounds
AU2011230496B2 (en) 2010-03-26 2015-09-17 Integrated Dna Technologies, Inc. Methods for enhancing nucleic acid hybridization

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4828979A (en) * 1984-11-08 1989-05-09 Life Technologies, Inc. Nucleotide analogs for nucleic acid labeling and detection
WO1986006726A1 (en) 1985-05-15 1986-11-20 Integrated Genetics, Inc. Cytidine analogs
JP2509574B2 (ja) 1985-08-15 1996-06-19 アモコ・コーポレーション 標識付けした核酸
US4981783A (en) 1986-04-16 1991-01-01 Montefiore Medical Center Method for detecting pathological conditions
FR2601956B1 (fr) 1986-07-22 1989-11-03 Pasteur Institut Nouveaux derives de desoxy-2' adenosine, leur procede d'obtention par voie de synthese et leurs applications biologiques
FR2607507B1 (fr) 1986-12-02 1990-04-13 Centre Nat Rech Scient Nouveaux derives a-d-oligonucleotides, leur preparation et leur emploi
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
EP0407816A3 (en) 1989-07-14 1993-01-27 Abbott Laboratories Base modified nucleosides
WO1992000989A1 (en) * 1990-07-10 1992-01-23 Imperial Chemical Industries Plc Non-isotopic nucleic acid labelling method
US5428148A (en) 1992-04-24 1995-06-27 Beckman Instruments, Inc. N4 - acylated cytidinyl compounds useful in oligonucleotide synthesis
US5571902A (en) * 1993-07-29 1996-11-05 Isis Pharmaceuticals, Inc. Synthesis of oligonucleotides
WO1995024185A1 (en) 1994-03-11 1995-09-14 Isis Pharmaceuticals, Inc. Novel pyrimidine nucleosides
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
CA2262019C (fr) * 1996-08-02 2011-11-15 Bio Merieux Procede d'amplification d'une sequence d'un acide nucleique cible
US6222030B1 (en) * 1998-08-03 2001-04-24 Agilent Technologies, Inc. Solid phase synthesis of oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection

Also Published As

Publication number Publication date
CA2357793A1 (fr) 2000-07-13
US6875858B1 (en) 2005-04-05
WO2000040590A2 (fr) 2000-07-13
EP1140963A2 (de) 2001-10-10
EP1140963B1 (de) 2004-09-22
WO2000040590A3 (fr) 2000-11-02
ATE277065T1 (de) 2004-10-15
AU3050800A (en) 2000-07-24
DE60014028T2 (de) 2006-03-02

Similar Documents

Publication Publication Date Title
DE60014028D1 (de) Funktionalisierte verbindung, gegebenenfalls markierte polynukleotide und verfahren zur detektion einer ziel-nukleinsäure
CA2255620A1 (en) Novel anandamide amidase inhibitors as analgesic agents
EP1152008A3 (de) Fluoreszente Nucleotide, enthaltend einen Cyanin, Merocyanin- oder Styryl-Farbstoff, zur Erkennung von Nucleinsäuren
ATE342896T1 (de) Fluoreszierende proben zur quantitativen bestimmung von zink
ATE296828T1 (de) Verbindungen zur floureszenz-kennzeichnung
ATE237626T1 (de) Verbindungen für massenspektrometrie bestehend aus nukleinsäure-basen und arylether-massmarkern
ATE282020T1 (de) Verfahren zur herstellung von 2-aminomalonsäure- derivaten
BR0013130A (pt) Composições para controlar cescimentos biológico e macrobiológico em fluidos industriais, e, processos para controlar crescimentos biológico e macrobiológico em um fluìdo industrial
DE60042601D1 (de) Verfahren zur regelung des nullpunktpotentials eines wandlers mit nullpunktbegrenzung
BR9813022A (pt) Derivados de ésteres hidroxiacéticos, seu processo de preparação e sua utilização como intermediários de sìntese
ATE208827T1 (de) Konjugate von dns und pns und verfahren zu deren herstellung
KR970704864A (ko) 세정제 조성물
ATE259370T1 (de) Verfahren zur herstellung von phosphinverbindungen
ATE221894T1 (de) Verfahren zur markierung von nukleotiden, markierte nukleotide und nuetzliche zwischenprodukte
ATE542917T1 (de) Zusammensetzungen, verfahren und kits zur bestimmung des vorhandenseins von trichomonas vaginalis in einer testprobe
ATE325871T1 (de) Verfahren zur erkennung des produkts einer nukleinsäuresynthetisierungsreaktion
AU5197599A (en) Fluorescent labelling reagents
DE60309251D1 (de) Verfahren zur Herstellung von Donepezil
DE69619410D1 (de) Zusammensetzungen für nukleinsäure zielrichtung
BR0115996A (pt) Sulfamidotienopirimidinas
EP1106621A3 (de) Fluoreszente materialen
IL151854A0 (en) Biotin-peg-substrate for a lipase assay
DE50001475D1 (de) Verfahren zur Herstellung von (Metall)salzen von Alkylphosphonigen Säuren II
DE60101391D1 (de) Verfahren zum Herstellen von Pivaloylessigsäureester
DE60127244D1 (de) Spezifische multiplex-analyse von nukleinsäuren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: WITTE, WELLER & PARTNER, 70178 STUTTGART