DE60034370D1 - Verfahren und vorrichtung zur analyse von zellen in einer vollblutprobe - Google Patents

Verfahren und vorrichtung zur analyse von zellen in einer vollblutprobe

Info

Publication number
DE60034370D1
DE60034370D1 DE60034370T DE60034370T DE60034370D1 DE 60034370 D1 DE60034370 D1 DE 60034370D1 DE 60034370 T DE60034370 T DE 60034370T DE 60034370 T DE60034370 T DE 60034370T DE 60034370 D1 DE60034370 D1 DE 60034370D1
Authority
DE
Germany
Prior art keywords
blood test
full blood
analyzing cells
analyzing
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60034370T
Other languages
English (en)
Other versions
DE60034370T2 (de
Inventor
Carlos M Rodriguez
Jose M Cano
Barbara Carrillo
Kristie M Gordon
Allan F Horton
Ronald D Paul
Mark A Wells
James L Wyatt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of DE60034370D1 publication Critical patent/DE60034370D1/de
Application granted granted Critical
Publication of DE60034370T2 publication Critical patent/DE60034370T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1019
    • G01N2015/139
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497Preparation composition [e.g., lysing or precipitation, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331Preservative, buffer, anticoagulant or diluent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
DE60034370T 1999-02-16 2000-02-03 Verfahren und vorrichtung zur analyse von zellen in einer vollblutprobe Expired - Lifetime DE60034370T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/251,019 US6228652B1 (en) 1999-02-16 1999-02-16 Method and apparatus for analyzing cells in a whole blood sample
US251019 1999-02-16
PCT/US2000/002715 WO2000049385A2 (en) 1999-02-16 2000-02-03 Method and apparatus for analyzing cells in a whole blood sample

Publications (2)

Publication Number Publication Date
DE60034370D1 true DE60034370D1 (de) 2007-05-24
DE60034370T2 DE60034370T2 (de) 2007-12-20

Family

ID=22950141

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60034370T Expired - Lifetime DE60034370T2 (de) 1999-02-16 2000-02-03 Verfahren und vorrichtung zur analyse von zellen in einer vollblutprobe

Country Status (5)

Country Link
US (1) US6228652B1 (de)
EP (1) EP1250585B1 (de)
JP (1) JP4468590B2 (de)
DE (1) DE60034370T2 (de)
WO (1) WO2000049385A2 (de)

Families Citing this family (152)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060322A (en) * 1998-10-20 2000-05-09 Coulter International Corp. Method for identification of reticulated cells
JP3817091B2 (ja) * 1999-07-02 2006-08-30 テルモ株式会社 細胞数測定装置
AU8026100A (en) * 1999-10-15 2001-04-30 The Administrators Of The Tulane Eductional Fund Device for and method of simultaneously measuring light scatter from multiple liquid samples
US6587792B1 (en) 2000-01-11 2003-07-01 Richard A. Thomas Nuclear packing efficiency
US6646742B1 (en) * 2000-02-19 2003-11-11 Mwi, Inc. Optical device and method for multi-angle laser light scatter
US6624621B2 (en) * 2000-04-03 2003-09-23 Howard L. North, Jr. Particle counter volume sensor
US6890489B2 (en) * 2000-04-26 2005-05-10 Rheodyne, L.P. Mass rate attenuator
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US6784981B1 (en) * 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
JP4494606B2 (ja) * 2000-08-11 2010-06-30 浜松ホトニクス株式会社 液体含有物質分析装置及び液体含有物質分析方法
US20020086431A1 (en) * 2000-08-21 2002-07-04 Markham Walter Bruce Sample preparation and slide plating apparatus and method
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
ATE434760T1 (de) * 2000-09-18 2009-07-15 Sysmex Corp Blutzellen-detektor, blutanalysegerät und blutanalyseverfahren unter verwendung des detektors
JP4759188B2 (ja) * 2000-09-18 2011-08-31 シスメックス株式会社 血球検出器及びそれを備えた血液分析装置
US7279883B2 (en) 2001-01-23 2007-10-09 Lydia L. Sohn Particle analyzer and methods for use thereof
US6743190B2 (en) * 2001-05-07 2004-06-01 Biomed Solutions L.L.C. Flow cytometer shunt
US6793642B2 (en) * 2001-05-07 2004-09-21 Biomed Solutions, Llc Flow cytometer
US20030027347A1 (en) * 2001-05-25 2003-02-06 Phyllis Shapiro Automated method for correcting blood analysis parameter results affected by interference from exogenous blood substitutes in whole blood, plasma, and serum
DE10128449B4 (de) * 2001-06-12 2004-07-15 Robert Bosch Gmbh Vorrichtung und Verfahren zur Prüfung eines Materials
US6472215B1 (en) * 2001-07-27 2002-10-29 Coulter International Corp. Method of analyzing nucleated red blood cells in a blood sample
US6410330B1 (en) * 2001-07-27 2002-06-25 Coulter International Corp. Method for measurement of nucleated red blood cells
CN1276252C (zh) * 2001-07-27 2006-09-20 贝克曼库尔特有限公司 有核红细胞的测量方法
US6803208B2 (en) * 2001-07-30 2004-10-12 The United States Of America As Represented By The Secretary Of The Navy Automated epifluorescence microscopy for detection of bacterial contamination in platelets
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
US8986944B2 (en) * 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US6723563B2 (en) 2001-12-03 2004-04-20 Streck Laboratories Inc. Hematology reference control
US6653137B2 (en) 2001-12-03 2003-11-25 Streck Laboratories Inc. Hematology reference control
DE60308259T2 (de) * 2002-05-22 2007-04-05 Sysmex Corp. Immunologische Verfahren, Vorrichtungen und Reagenzien
US7569393B2 (en) 2002-06-28 2009-08-04 International Technidyne Corporation Analytical test cartridge; and, methods
JP4299597B2 (ja) * 2002-07-29 2009-07-22 シスメックス株式会社 血液分析装置及び方法
US6794877B2 (en) * 2002-07-31 2004-09-21 International Technidyne Corporation Apparatus and method for analytical determinations
US6743634B2 (en) * 2002-08-23 2004-06-01 Coulter International Corp. Method and apparatus for differentiating blood cells using back-scatter
US20040166540A1 (en) * 2003-02-24 2004-08-26 Sysmex Corporation Methods of detecting CD34 positive and negative hematopoietic stem cells in human samples
US20040219612A1 (en) * 2003-05-02 2004-11-04 Beckman Coulter, Inc. Methods for detecting intracellular defensins in various leukocyte subpopulations
US20040228765A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
US20040228766A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
JP2005024472A (ja) * 2003-07-04 2005-01-27 Sysmex Corp 幼若血小板測定装置
WO2005043113A2 (en) * 2003-10-12 2005-05-12 Beckman Coulter, Inc. Method of using a reference control composition for measurement of nucleated red blood cells
US7095492B2 (en) * 2003-12-19 2006-08-22 Beckman Coulter, Inc. Method and apparatus for measuring cell-by-cell hemoglobin
JP4861830B2 (ja) * 2003-12-24 2012-01-25 グライコフィ, インコーポレイテッド 糖タンパク質の産生において、グリカンのマンノシルリン酸化を除去する方法
JP4435581B2 (ja) * 2004-01-07 2010-03-17 シスメックス株式会社 免疫測定装置および方法
US7008792B2 (en) * 2004-02-10 2006-03-07 Beckman Coulter, Inc. Method of measurement of nucleated red blood cells
US7208319B2 (en) * 2004-02-10 2007-04-24 Beckman Coulter, Inc. Method of measurement of nucleated red blood cells
JP4417143B2 (ja) * 2004-03-11 2010-02-17 シスメックス株式会社 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体
US7625712B2 (en) 2004-05-21 2009-12-01 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
US7674598B2 (en) * 2004-05-21 2010-03-09 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
US7075647B2 (en) * 2004-06-30 2006-07-11 Beckman Coulter, Inc. Back-scatter detection in flow cytometers
US7340957B2 (en) 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
FR2873813B1 (fr) * 2004-07-30 2006-11-17 Abx Sa Procede et dispositif de caracterisation des composants cellulaires d'un liquide biologique
US20080061969A1 (en) * 2004-08-04 2008-03-13 Matsushita Electric Industrial Co., Ltd. Invasion Detection Device
US8685711B2 (en) * 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
US7392908B2 (en) * 2005-01-12 2008-07-01 Beckman Coulter, Inc. Methods and apparatus for sorting particles hydraulically
US7678578B2 (en) * 2005-02-07 2010-03-16 Beckman Coulter, Inc. Cell permeabilization and stabilization reagent and method of use
US20070077177A1 (en) * 2005-03-16 2007-04-05 Klaus Witt Stimulated detection of sample compounds
US7113266B1 (en) * 2005-03-30 2006-09-26 Beckman Coulter, Inc. Flow cytometer for differentiating small particles in suspension
FR2883973B1 (fr) * 2005-03-31 2007-11-16 C2 Diagnostics Sa Cuve pour dispositif optique d'analyse sanguine, appareil d'analyse equipe d'une telle cuve
US7842247B2 (en) 2005-08-19 2010-11-30 Canadian Blood Services Sample holder for dynamic light scattering
US7609369B2 (en) * 2005-09-24 2009-10-27 Beckman Coulter, Inc. Methods of detection of iron deficiency and hemochromatosis
US7344890B2 (en) * 2005-11-09 2008-03-18 Beckman Coulter, Inc. Method for discriminating platelets from red blood cells
JP5431732B2 (ja) * 2005-12-29 2014-03-05 ハネウェル・インターナショナル・インコーポレーテッド マイクロ流体フォーマットにおけるアッセイ実装
EP2016423B1 (de) * 2006-01-20 2011-07-13 Beckman Coulter, Inc. Verfahren zum nachweis von eisenmangel
EP2029999A2 (de) * 2006-05-13 2009-03-04 Dako Denmark A/S Verfahren für durchflusszytometrie-analysen von zellen ohne lysieren von subpopulationen
CN101583722A (zh) * 2006-07-14 2009-11-18 阿维瓦生物科学股份有限公司 从生物学样品检测稀有细胞的方法和组合物
US7947487B2 (en) 2006-10-05 2011-05-24 Massachusetts Institute Of Technology Multifunctional encoded particles for high-throughput analysis
CN1945326A (zh) * 2006-10-13 2007-04-11 江西特康科技有限公司 基于视觉形态的五分类全血细胞分析方法
US7835000B2 (en) 2006-11-03 2010-11-16 Los Alamos National Security, Llc System and method for measuring particles in a sample stream of a flow cytometer or the like
WO2008061058A2 (en) * 2006-11-10 2008-05-22 Luminex Corporation Flow cytometer and fluidic line assembly with multiple injection needles
US20080121591A1 (en) * 2006-11-29 2008-05-29 Canon U.S. Life Sciences, Inc. Device for nucleic acid preparation
US7674622B2 (en) * 2006-12-22 2010-03-09 Abbott Laboratories, Inc. Method for determination of nucleated red blood cells and leukocytes in a whole blood sample in an automated hematology analyzer
EP3260842B1 (de) * 2007-02-01 2022-04-13 Sysmex Corporation Hämatologischer analysator und verfahren zur analyse einer probe
US8083068B2 (en) 2007-04-09 2011-12-27 Los Alamos National Security, Llc Apparatus for separating particles utilizing engineered acoustic contrast capture particles
US7837040B2 (en) * 2007-04-09 2010-11-23 Los Alamos National Security, Llc Acoustic concentration of particles in fluid flow
US7618821B2 (en) 2007-04-13 2009-11-17 Streck, Inc. Simulated blood components and methods
JP5162177B2 (ja) * 2007-07-31 2013-03-13 シスメックス株式会社 粒子分析装置及び粒子分析方法
US8263407B2 (en) 2007-10-24 2012-09-11 Los Alamos National Security, Llc Method for non-contact particle manipulation and control of particle spacing along an axis
US8528406B2 (en) * 2007-10-24 2013-09-10 Los Alamos National Security, LLP Method for non-contact particle manipulation and control of particle spacing along an axis
WO2009058876A1 (en) * 2007-10-29 2009-05-07 Beckman Coulter, Inc. Method for a rapid antibody-based analysis of platelet populations
US8266951B2 (en) 2007-12-19 2012-09-18 Los Alamos National Security, Llc Particle analysis in an acoustic cytometer
US9602777B2 (en) 2008-04-25 2017-03-21 Roche Diagnostics Hematology, Inc. Systems and methods for analyzing body fluids
WO2012030313A1 (en) 2008-04-25 2012-03-08 James Winkelman Method of determining a complete blood count and a white blood cell differential count
US8094299B2 (en) * 2008-07-24 2012-01-10 Beckman Coulter, Inc. Transducer module
TW201017149A (en) * 2008-08-06 2010-05-01 Invitrox Inc Use of focused light scattering techniques in biological applications
US20100086962A1 (en) 2008-10-08 2010-04-08 Streck, Inc. Hematology controls and methods
US8000940B2 (en) 2008-10-08 2011-08-16 Beckman Coulter, Inc. Shape parameter for hematology instruments
HU227875B1 (en) * 2008-10-13 2012-05-29 Diatron Medicinai Instr Laboratoriumi Diagnosztikai Fejlesztoe Gyarto Zartkoerueen Muekoedoe Reszven Optical circulation cytometer furthermore testing method
FR2939199B1 (fr) 2008-12-02 2011-02-11 C2 Diagnostics Procede et dispositif de cytometrie en flux sans fluide de gainage
US9464978B2 (en) * 2009-03-04 2016-10-11 Beckman Coulter, Inc. Cross-instrument method and system for cell population discrimination
JP5670052B2 (ja) * 2009-03-26 2015-02-18 シスメックス株式会社 血液分析装置、血液分析方法及びコンピュータプログラム
EP2422181A1 (de) * 2009-04-24 2012-02-29 Beckman Coulter, Inc. Verfahren zur charakterisierung von partikeln
WO2010138391A2 (en) * 2009-05-26 2010-12-02 Invitrox, Inc. Instrument and method for optical particle sensing
US20100329927A1 (en) 2009-06-26 2010-12-30 Perez Carlos A Pipelining Assembly For A Blood Analyzing Instrument
US9097704B2 (en) * 2010-05-05 2015-08-04 Abbott Laboratories Method for hematology analysis
WO2011156434A2 (en) 2010-06-07 2011-12-15 Firefly Bioworks, Inc. Nucleic acid detection and quantification by post-hybridization labeling and universal encoding
JP5868982B2 (ja) 2010-09-16 2016-02-24 ザ ジェネラル ホスピタル コーポレイション 診断のための赤血球動力学
WO2012059784A1 (en) 2010-11-03 2012-05-10 Reametrix Inc Method and device for fluorescent measurement of samples
US9111343B2 (en) 2011-01-18 2015-08-18 Roche Diagnostics Hematology, Inc. Microscope slide coordinate system registration
FR2971337B1 (fr) * 2011-02-04 2013-03-01 Horiba Abx Sas Dispositif et procede de mesures multiparametriques de microparticules dans un fluide
CN103492875B (zh) * 2011-04-28 2016-03-09 希森美康株式会社 血液分析装置及血液分析方法
US9103759B2 (en) 2011-05-04 2015-08-11 Abbott Laboratories Nucleated red blood cell analysis system and method
US9091624B2 (en) 2011-05-04 2015-07-28 Abbott Laboratories White blood cell analysis system and method
EP3650831A1 (de) 2011-05-04 2020-05-13 Abbott Laboratories System und verfahren zur analyse basophiler stoffe
EP2520926B1 (de) * 2011-05-05 2022-06-15 Sysmex Corporation Blutanalysegerät, blutanalyseverfahren und computerprogrammprodukt
WO2013013229A1 (en) 2011-07-21 2013-01-24 Invitrox, Inc. Instrument and method for optical particle sensing
US9201005B2 (en) 2011-12-29 2015-12-01 Abbott Laboratories Flow cytometry systems and methods for blocking diffraction patterns
EP2823285A1 (de) * 2012-03-09 2015-01-14 Firefly Bioworks, Inc. Verfahren und vorrichtung zur klassifizierung und quantifizierung von multifunktionsobjekten
CN104541149B (zh) 2012-07-05 2017-03-01 贝克曼考尔特公司 用于确定白血细胞计数的方法和装置
JP2015524571A (ja) * 2012-08-13 2015-08-24 ベックマン コールター, インコーポレイテッド Cpdデータを使用した白血病分類
US20140160464A1 (en) 2012-11-30 2014-06-12 Beckman Coulter, Inc. Tuberculosis screening using cpd data
EP2939000A1 (de) * 2012-12-31 2015-11-04 Beckman Coulter, Inc. Systeme und verfahren zur zählung unreifer blutplättchen
BR112015010498B1 (pt) 2012-12-31 2020-09-29 Beckman Coulter, Inc Sistema de hematologia para determinar uma contagem de plaquetas em uma amostra biológica, e método automatizado para determinar uma contagem de plaquetas em uma amostra biológica
JP6343660B2 (ja) * 2013-03-11 2018-06-13 ロッシュ ダイアグノスティクス ヘマトロジー インコーポレイテッド 血球の撮像
EP3650853A1 (de) * 2013-03-12 2020-05-13 Abbott Laboratories Reagenzien, systeme und verfahren zur analyse von erythrozyten und blutplättchen
US9772274B2 (en) 2013-03-15 2017-09-26 Beckman Coulter, Inc. Compound optical flow cells and method of manufacture and use
WO2014144826A1 (en) 2013-03-15 2014-09-18 Beckman Coulter, Inc. Systems and methods for panel design in flow cytometry
EP2997363A4 (de) * 2013-05-13 2016-11-30 Chiranjit Deka Zellanalysevorrichtungen und -verfahren
US10324020B2 (en) * 2013-12-23 2019-06-18 Palo Alto Research Center Incorporated Fluidic optical cartridge
CN107003224B (zh) * 2014-08-20 2021-01-12 生物辐射实验室股份有限公司 光流体分选器
US9500588B2 (en) 2014-09-30 2016-11-22 Perkinelmer Health Sciences, Inc. Flow cell modules and liquid sample analyzers and methods including same
US9581491B2 (en) 2014-09-30 2017-02-28 Perkinelmer Health Sciences, Inc. Flow cell modules and liquid sample analyzers and methods including same
US9612221B2 (en) 2014-10-14 2017-04-04 Chem-Aqua, Inc. + Pyxis Lab, Inc. Opto-electrochemical sensing system for monitoring and controlling industrial fluids
FR3034198B1 (fr) 2015-03-26 2019-05-31 C2 Diagnostics Appareil hydrofocus a solution d'analyse unique
JP6729558B2 (ja) * 2015-03-31 2020-07-22 ソニー株式会社 電気的特性測定装置、電気的特性測定方法、血液状態解析システム、及び該方法をコンピューターに実現させるための電気的特性測定用プログラム
EP3371591A4 (de) 2015-11-02 2018-11-14 Chiranjit Deka Lichtstreuerbasierte vorrichtung und verfahren zur hämatologieanalyse mit verwendung von nur drei detektoren
WO2017106461A1 (en) 2015-12-15 2017-06-22 The General Hospital Corporation Methods of estimating blood glucose and related systems
EP3408773B1 (de) 2016-01-28 2023-09-20 Beckman Coulter, Inc. Systeme und verfahren zur erkennung und differenzierung von infektionen
WO2017177192A1 (en) 2016-04-07 2017-10-12 The General Hospital Corporation White blood cell population dynamics
EP3465142B1 (de) * 2016-05-27 2023-08-23 Martin Kuhn Durchflusszytometeranordnung
WO2018148942A1 (zh) * 2017-02-17 2018-08-23 深圳迈瑞生物医疗电子股份有限公司 血液细胞分析方法及血液细胞分析仪
KR20190120318A (ko) 2017-02-28 2019-10-23 베크만 컬터, 인코포레이티드 상호 운용 질병 관리 시스템
US10648909B2 (en) * 2017-05-25 2020-05-12 Abbott Laboratories Methods and systems for assessing flow cell cleanliness
CN109211737A (zh) * 2017-06-30 2019-01-15 深圳迈瑞生物医疗电子股份有限公司 样本检测装置、样本分析仪及样本检测方法
CN111033254A (zh) * 2017-08-31 2020-04-17 深圳迈瑞生物医疗电子股份有限公司 样本检测装置、样本分析仪及样本检测方法
US11852640B2 (en) 2017-10-27 2023-12-26 Beckman Coulter, Inc. Hematology analyzers and methods of operation
US10914913B2 (en) 2018-03-30 2021-02-09 Idexx Laboratories, Inc. Flow cytometer, laser optics assembly thereof, and methods of assembling the same
US11521706B2 (en) 2018-04-20 2022-12-06 Beckman Coulter, Inc. Testing and representing suspicion of sepsis
US11644464B2 (en) 2018-04-20 2023-05-09 Beckman Coulter, Inc. Sepsis infection determination systems and methods
US11538566B2 (en) 2018-05-23 2022-12-27 Beckman Coulter, Inc. Sample analysis with test determination based on identified condition
EP3784397A4 (de) * 2018-04-23 2022-01-19 ANPAC Bio-Medical Science Co., Ltd. Neue vorrichtung und verfahren zur erkennung von erkrankungen
CN117825345A (zh) * 2018-04-28 2024-04-05 深圳迈瑞生物医疗电子股份有限公司 一种血液分析仪及分析方法
US11022538B2 (en) * 2018-05-15 2021-06-01 Government Of The United States Of America, As Represented By The Secretary Of Commerce Quantum flow cytometer
US20190383800A1 (en) * 2018-06-15 2019-12-19 Beckman Coulter, Inc. Method of determining sepsis in the presence of blast flagging
JP2022540157A (ja) 2019-07-12 2022-09-14 ベックマン コールター, インコーポレイテッド 感染に対する免疫応答を評価するためのシステムおよび方法
US11796447B2 (en) 2019-07-12 2023-10-24 Beckman Coulter, Inc. Systems and methods for using cell granularitry in evaluating immune response to infection
EP4139655A1 (de) 2020-04-21 2023-03-01 Beckman Coulter, Inc. Nachweis von medizinischen zuständen, schweregrad, risiko und sehschärfe unter verwendung von parametern
WO2021257553A1 (en) 2020-06-17 2021-12-23 Idexx Laboratories Inc. Flow cytometer and laser optics assembly thereof
EP3933376A1 (de) * 2020-07-02 2022-01-05 Deutsches Rheuma-Forschungszentrum Berlin Verfahren und system zur charakterisierung von teilchen mittels winkeldetektion in einem durchflusszytometer
EP4179322A1 (de) * 2020-07-10 2023-05-17 Beckman Coulter Inc. Automatisierte probenvorbereitungsplattform für zellanalyse
CN116529586A (zh) 2020-09-25 2023-08-01 贝克曼库尔特有限公司 用于评价与covid-19相关的mis-c的方法
CN112557281B (zh) * 2020-11-23 2022-06-24 深圳市科曼医疗设备有限公司 血液细胞分析仪的plt粒子检测方法和装置
CN116762011A (zh) 2020-12-02 2023-09-15 贝克曼库尔特有限公司 发展成脓毒症的概率的检测
WO2023159188A1 (en) 2022-02-18 2023-08-24 Beckman Coulter, Inc. Detection of sepsis using hematology parameters
US11506587B1 (en) * 2022-06-29 2022-11-22 HLM Diagnostics Inc. Liquid droplet and solid particle sensing device

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673288A (en) * 1981-05-15 1987-06-16 Ratcom, Inc. Flow cytometry
US4507977A (en) 1981-10-19 1985-04-02 Coulter Electronics, Inc. Liquid metering and transfer valve assembly
US4445391A (en) 1981-10-19 1984-05-01 Coulter Electronics, Inc. Liquid metering and transfer valve assembly
US4510438A (en) * 1982-02-16 1985-04-09 Coulter Electronics, Inc. Coincidence correction in particle analysis system
GB2125181B (en) * 1982-08-11 1986-01-29 Coulter Electronics Flow cells for particle study
CH651930A5 (en) * 1983-03-24 1985-10-15 Coulter Corp Apparatus for analysis and sorting of particles
US4702889A (en) 1986-01-16 1987-10-27 Coulter Electronics Inc. Liquid sampling valve
KR970007077B1 (ko) 1987-03-13 1997-05-02 코울터 일렉트로닉스 인커퍼레이티드 광산란 기술을 이용한 다중-부분식별 분석 방법
FR2621123B1 (fr) * 1987-09-30 1989-12-01 Commissariat Energie Atomique Procede de fabrication d'un dispositif d'analyse optique d'un flux de microparticules et application a la fabrication d'un cytofluorimetre
JPH0718785B2 (ja) 1988-09-19 1995-03-06 株式会社日立製作所 フローセル装置
CA1324894C (en) * 1989-03-31 1993-12-07 Maritime Scientific Services Ltd. Method and apparatus for the identification of particles
US5255568A (en) 1990-12-13 1993-10-26 Coulter Corporation Liquid sample/reagent metering and delivery method
JP3048260B2 (ja) * 1991-07-29 2000-06-05 シスメックス株式会社 白血球分類計数用試料調製方法
JP3707620B2 (ja) * 1993-05-14 2005-10-19 コールター インターナショナル コーポレイション 光散乱技術を使用した網赤血球分析方法と装置
JP3328032B2 (ja) * 1993-11-04 2002-09-24 シスメックス株式会社 粒子分析装置
IL113805A0 (en) * 1994-05-23 1995-08-31 Coulter Corp Detection of reticulocytes
DE69532045T2 (de) * 1994-08-01 2004-07-08 Abbott Laboratories, Abbott Park Verfahren und Vorrichtung zur Vorbereitung einer Flüssigkeit
US5631165A (en) 1994-08-01 1997-05-20 Abbott Laboratories Method for performing automated hematology and cytometry analysis
US5656499A (en) 1994-08-01 1997-08-12 Abbott Laboratories Method for performing automated hematology and cytometry analysis
US5798827A (en) * 1996-11-26 1998-08-25 Coulter International Corp. Apparatus and method for determination of individual red blood cell shape
US6060322A (en) * 1998-10-20 2000-05-09 Coulter International Corp. Method for identification of reticulated cells

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WO2000049385A2 (en) 2000-08-24
EP1250585B1 (de) 2007-04-11
WO2000049385A3 (en) 2002-08-08
DE60034370T2 (de) 2007-12-20
US6228652B1 (en) 2001-05-08

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