DE60042174D1 - Systeme und verfahren zur topischen behandlung mit stickstoffmonoxyd - Google Patents

Systeme und verfahren zur topischen behandlung mit stickstoffmonoxyd

Info

Publication number
DE60042174D1
DE60042174D1 DE60042174T DE60042174T DE60042174D1 DE 60042174 D1 DE60042174 D1 DE 60042174D1 DE 60042174 T DE60042174 T DE 60042174T DE 60042174 T DE60042174 T DE 60042174T DE 60042174 D1 DE60042174 D1 DE 60042174D1
Authority
DE
Germany
Prior art keywords
gel
hydroxyethylcellulose
burns
intra
gels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60042174T
Other languages
English (en)
Inventor
William A Seitz
Robert E Garfield
Alexandru T Balaban
Randall J Stewart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIOXX LLC, DICKINSON, TEX., US
Original Assignee
Nitric Oxide Solutions
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22250448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60042174(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nitric Oxide Solutions filed Critical Nitric Oxide Solutions
Application granted granted Critical
Publication of DE60042174D1 publication Critical patent/DE60042174D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
DE60042174T 1998-06-10 2000-05-24 Systeme und verfahren zur topischen behandlung mit stickstoffmonoxyd Expired - Lifetime DE60042174D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/095,174 US6103275A (en) 1998-06-10 1998-06-10 Systems and methods for topical treatment with nitric oxide
PCT/US2000/014239 WO2001089572A1 (en) 1998-06-10 2000-05-24 Systems and methods for topical treatment with nitric oxide

Publications (1)

Publication Number Publication Date
DE60042174D1 true DE60042174D1 (de) 2009-06-18

Family

ID=22250448

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60042174T Expired - Lifetime DE60042174D1 (de) 1998-06-10 2000-05-24 Systeme und verfahren zur topischen behandlung mit stickstoffmonoxyd

Country Status (7)

Country Link
US (2) US6103275A (de)
EP (1) EP1283724B1 (de)
AT (1) ATE430584T1 (de)
AU (2) AU5042600A (de)
CA (1) CA2410990C (de)
DE (1) DE60042174D1 (de)
WO (1) WO2001089572A1 (de)

Families Citing this family (210)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709681B2 (en) * 1995-02-17 2004-03-23 Aberdeen University Acidified nitrite as an antimicrobial agent
US7914814B2 (en) * 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
US6207713B1 (en) * 1997-09-17 2001-03-27 Eric T. Fossel Topical and oral delivery of arginine to cause beneficial effects
US7629384B2 (en) * 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
US6103275A (en) * 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide
US20070086954A1 (en) * 1998-11-23 2007-04-19 Miller Christopher C Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
CA2254645A1 (en) * 1998-11-23 2000-05-23 Pulmonox Medical Corporation Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
GB9905425D0 (en) * 1999-03-09 1999-05-05 Queen Mary & Westfield College Pharmaceutical composition
US20050142218A1 (en) * 2000-03-09 2005-06-30 Queen Mary & Westfield College Pharmaceutical composition containing nitrate source and an acidifying agent for treating skin ischaemia
DE19945484A1 (de) * 1999-09-22 2001-04-05 Kolb Bachofen Victoria NO-freisetzende topisch applizierbare Zusammensetzung
US7516742B2 (en) * 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
AU5022101A (en) 2000-04-26 2001-11-07 Univ Kingston Formulations and methods of using nitric oxide mimetics against a malignant cellphenotype
US20050142217A1 (en) * 2000-04-26 2005-06-30 Adams Michael A. Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype
US7678391B2 (en) * 2000-04-26 2010-03-16 Queen's University At Kingston Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype
GB0021317D0 (en) * 2000-08-30 2000-10-18 Queen Mary & Westfield College Transdermal pharmaceutical delivery composition
SE0004026D0 (sv) * 2000-11-03 2000-11-03 Peter Wiklund New use
US7122018B2 (en) * 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
US6432077B1 (en) * 2000-12-26 2002-08-13 Sensormedics Corporation Device and method for treatment of surface infections with nitric oxide
US6706274B2 (en) 2001-01-18 2004-03-16 Scimed Life Systems, Inc. Differential delivery of nitric oxide
GB0119011D0 (en) * 2001-08-03 2001-09-26 Univ Aberdeen Treatment of nail infections
EP2565157B1 (de) * 2001-09-05 2017-10-04 Geno LLC Stickoxid-erzeugung
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
EP1496951B1 (de) * 2002-04-24 2006-06-14 Insense Limited Wundauflage enthaltend ein oxidoreduktase-enzym in hydratiertem zustand
US20040018237A1 (en) 2002-05-31 2004-01-29 Perricone Nicholas V. Topical drug delivery using phosphatidylcholine
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
GB0224986D0 (en) * 2002-10-28 2002-12-04 Smith & Nephew Apparatus
US9138707B2 (en) 2002-12-10 2015-09-22 Sy Kimball Portable, nitric oxide generator
CA2413834A1 (en) 2002-12-10 2004-06-10 1017975 Alberta Limited Nitric oxide gas generator
FR2850578B1 (fr) * 2003-02-03 2006-07-28 Oreal Utilisation de n-arylmethylene ethylenediaminetriacetates, n-arylmethyleneiminodiacetates ou n,n'-diarylmethylene ethylenediamineacetates comme donneurs de no
CA2456035A1 (fr) * 2003-02-03 2004-08-03 L'oreal Utilisation de n-arylmethylene ethylenediaminetriacetates, n-arylmethyleneiminodiacetates ou n,n'-diarylmethylene ethylenediamineacetates comme donneurs de no
FR2850579B1 (fr) * 2003-02-03 2006-08-18 Oreal Utilisation de mono-ou di-esters d'acide cinnamique ou de l'un de ses derives et de vitamine c, comme donneur de no
CN104257454A (zh) * 2003-04-23 2015-01-07 阿克伦大学 附连的反应材料
GB0313217D0 (en) 2003-06-09 2003-07-16 Insense Ltd Improvements in or relating to skin dressings
US20050181026A1 (en) * 2003-06-09 2005-08-18 Insense Limited Skin dressings
EP1648826B1 (de) * 2003-07-03 2017-08-23 The University Court of the University of St. Andrews Zeolithe zur freisetzung von stickstoffmonoxid
CA2537222A1 (en) * 2003-07-09 2005-01-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of nitrite salts for the treatment of cardiovascular conditions
US20090136410A1 (en) * 2003-07-25 2009-05-28 Smith Daniel J Stabilization and ionic triggering of nitric oxide release
GB0322342D0 (en) * 2003-09-23 2003-10-22 Gamble Reed Skin patch
US11298453B2 (en) 2003-10-28 2022-04-12 Smith & Nephew Plc Apparatus and method for wound cleansing with actives
CN100475275C (zh) * 2004-01-05 2009-04-08 董永华 肿瘤血管栓塞剂及其储存和释放装置
CA2554194C (en) * 2004-01-30 2012-01-10 Insense Limited Wound dressings comprising hydrated hydrogels and enzymes
EP1732577B1 (de) * 2004-02-23 2013-04-10 Strategic Science & Technologies, LLC Topische verabreichung von l-arginin zur verbesserung des aussehens von körper und haut
US20110028548A1 (en) * 2004-04-19 2011-02-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
WO2005102282A1 (en) 2004-04-19 2005-11-03 Strategic Science & Technologies, Llc Transdermal delivery of beneficial substances effected by a hostile biophysical environment
US20090105336A1 (en) * 2004-04-19 2009-04-23 Strategic Science & Technologies, Llc Beneficial Effects of Increasing Local Blood Flow
US8529548B2 (en) 2004-04-27 2013-09-10 Smith & Nephew Plc Wound treatment apparatus and method
US7753894B2 (en) 2004-04-27 2010-07-13 Smith & Nephew Plc Wound cleansing apparatus with stress
US10413644B2 (en) 2004-04-27 2019-09-17 Smith & Nephew Plc Wound treatment apparatus and method
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
EP1755715A4 (de) * 2004-05-11 2010-03-24 Sensormedics Corp Intermittierende dosierung von stickoxidgas
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7560076B2 (en) 2004-08-18 2009-07-14 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US8635217B2 (en) * 2004-09-15 2014-01-21 Michael J. Markus Collections of linked databases
US8880521B2 (en) * 2004-09-15 2014-11-04 3Degrees Llc Collections of linked databases
US8412706B2 (en) 2004-09-15 2013-04-02 Within3, Inc. Social network analysis
US20070260599A1 (en) * 2004-09-15 2007-11-08 Mcguire Heather A Social network analysis
US8577886B2 (en) * 2004-09-15 2013-11-05 Within3, Inc. Collections of linked databases
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
GB0505035D0 (en) * 2005-03-11 2005-04-20 Insense Ltd Improvements relating to skin dressings
FR2883165B1 (fr) * 2005-03-15 2007-05-18 Oreal Composition cosmetique anhydre contenant du monoxyde d'azote dans un materiau solide cristallin microporeux
WO2006097349A1 (en) * 2005-03-15 2006-09-21 L'oreal Cosmetic use of a microporous solid crystalline material no for improving the natural colouring and/or appearance of the skin and/or lips
FR2883163B1 (fr) * 2005-03-15 2007-05-18 Oreal Utilisation cosmetique d'un materiau solide cristallin microporeux contenant du no pour ameliorer l'aspect et/ou la coloration naturelle de la peau et/ou des levres
WO2006097351A1 (en) * 2005-03-15 2006-09-21 L'oreal Anhydrous cosmetic composition comprising nitrogen monoxide in a microporous solid crystalline material
WO2006097352A1 (en) * 2005-03-15 2006-09-21 L'oreal Cosmetic composition containing nitrogen monoxide in a microporous crystalline solid material
FR2883166B1 (fr) * 2005-03-15 2007-05-18 Oreal Composition cosmetique anhydre contenant du monoxyde d'azote dans un materiau solide cristallin microporeux
JP5042209B2 (ja) 2005-03-24 2012-10-03 ノーラブズ エービー 酸化窒素による美容治療、前記治療を実施する装置、及びその製造方法
EP1704876A1 (de) * 2005-03-24 2006-09-27 NOLabs AB Kosmetische Behandlung, Vorrichtung zur Durchführung dieser Behandlung und deren Herstellungsmethode
WO2006125123A2 (en) * 2005-05-19 2006-11-23 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
JP5274248B2 (ja) 2005-05-27 2013-08-28 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 酸化窒素治療及び医生物的応用のための酸化窒素放出粒子
WO2007005463A2 (en) * 2005-06-29 2007-01-11 S.M.A.R.T. Link Medical, Inc. Collections of linked databases
SE529058C2 (sv) 2005-07-08 2007-04-17 Plasma Surgical Invest Ltd Plasmaalstrande anordning, plasmakirurgisk anordning, användning av en plasmakirurgisk anordning och förfarande för att bilda ett plasma
SE529053C2 (sv) 2005-07-08 2007-04-17 Plasma Surgical Invest Ltd Plasmaalstrande anordning, plasmakirurgisk anordning och användning av en plasmakirurgisk anordning
SE529056C2 (sv) 2005-07-08 2007-04-17 Plasma Surgical Invest Ltd Plasmaalstrande anordning, plasmakirurgisk anordning och användning av en plasmakirurgisk anordning
WO2007016252A2 (en) * 2005-07-27 2007-02-08 S.M.A.R.T. Link Medical, Inc. Collections of linked databases and systems and methods for communicating about updates thereto
CN101257938A (zh) 2005-09-07 2008-09-03 泰科保健集团有限合伙公司 具有真空储存器的伤口敷料
US10395326B2 (en) * 2005-11-15 2019-08-27 3Degrees Llc Collections of linked databases
WO2007057763A2 (en) * 2005-11-18 2007-05-24 Pulmonox Technologies Corporation Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
CN1990045B (zh) * 2005-12-30 2010-12-22 北京尼奥克斯生物科技有限公司 一种新型高效烧烫伤类贴剂及其制备方法
US8790715B2 (en) * 2006-02-16 2014-07-29 Ino Therapeutics Llc Method and apparatus for generating nitric oxide for medical use
GB0614278D0 (en) * 2006-07-19 2006-08-30 Insense Ltd Hydrogen peroxide delivery system
GB0618711D0 (en) * 2006-09-22 2006-11-01 Univ Exeter Agricultural treatment
US8079998B2 (en) * 2006-10-20 2011-12-20 Pulmonox Technologies Corporation Methods and devices for the delivery of therapeutic gases including nitric oxide
US20100143503A1 (en) * 2006-12-22 2010-06-10 Ikaria, Inc. Combinations of nitric oxide and sulfide and methods of use and manufacture thereof
US7928338B2 (en) 2007-02-02 2011-04-19 Plasma Surgical Investments Ltd. Plasma spraying device and method
US20080193385A1 (en) * 2007-02-08 2008-08-14 Todd Maibach Compositions and methods for treating neuropathy
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
US7947227B2 (en) * 2007-03-23 2011-05-24 Geno Llc Kit for the conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US20100178319A1 (en) * 2007-03-27 2010-07-15 Lars Lindgren Topical Dermal Delivery Device For Nitric Oxide Delivery
WO2008126088A2 (en) * 2007-04-15 2008-10-23 Oron Zachar Anti-pyretic vasodilators
US10207927B2 (en) * 2007-04-26 2019-02-19 Ludlum Measurements, Inc. Method to produce a calibration, reagent or therapeutic gas by exposing a precursor gas to ultraviolet light
US7589473B2 (en) 2007-08-06 2009-09-15 Plasma Surgical Investments, Ltd. Pulsed plasma device and method for generating pulsed plasma
US8735766B2 (en) 2007-08-06 2014-05-27 Plasma Surgical Investments Limited Cathode assembly and method for pulsed plasma generation
GB0715556D0 (en) * 2007-08-09 2007-09-19 Insense Ltd Improvements relating to skin dressings
US9278157B2 (en) 2007-08-09 2016-03-08 Insense Limited Nitric oxide-generating skin dressings
US20090130233A1 (en) * 2007-10-24 2009-05-21 Baker Christopher G Two part lotion
EP2219657A4 (de) * 2007-11-15 2020-01-08 Louisiana State University Verwendung von nitritsalzen bei chronischer ischämie
WO2009086470A2 (en) * 2007-12-27 2009-07-09 Aires Pharmaceuticals, Inc. Aerosolized nitrite and nitric oxide - donating compounds and uses thereof
WO2009093169A1 (en) * 2008-01-22 2009-07-30 Koninklijke Philips Electronics N.V. Device for the topical delivery of nitric oxide to a skin surface
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
EP2247381B1 (de) 2008-01-28 2016-11-30 Geno LLC Umwandlung von stickstoffdioxid (no2) in stickstoffmonoxid (no)
US8720436B2 (en) * 2008-01-31 2014-05-13 Genosys, Inc. Nitric oxide gel apparatus and method
US8303995B1 (en) * 2008-06-13 2012-11-06 Board Of Regents, The University Of Texas System Nitrite formulations and their use as nitric oxide prodrugs
CA2728789A1 (en) * 2008-06-24 2009-12-30 Micropharma Limited Nitric oxide compositions and devices and methods for cosmesis
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
US8650937B2 (en) 2008-09-19 2014-02-18 Tandem Diabetes Care, Inc. Solute concentration measurement device and related methods
US20120237617A1 (en) 2009-06-18 2012-09-20 Theravasc Inc. Use of nitrite salts in treating tissue damage
US8613958B2 (en) 2009-06-22 2013-12-24 Geno Llc Nitric oxide therapies
ES2607476T3 (es) 2009-06-24 2017-03-31 Strategic Science & Technologies, Llc Composición tópica que contiene ibuprofeno
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
WO2010151241A1 (en) 2009-06-24 2010-12-29 Strategic Science & Technologies, Llc Topical composition containing naproxen
EP2724739B1 (de) 2009-07-30 2015-07-01 Tandem Diabetes Care, Inc. Tragbares Infusionspumpensystem
BR112012003804B1 (pt) 2009-08-21 2019-02-19 Novan, Inc. Curativo para ferimentos, método para formar um curativo para ferimentos, e, kit de curativo para ferimento
EP2467127B1 (de) 2009-08-21 2023-08-02 Novan, Inc. Topische gele
WO2011063335A1 (en) * 2009-11-20 2011-05-26 Geno Llc Nitric oxide delivery system
WO2011085484A1 (en) * 2010-01-13 2011-07-21 Nitric Solutions Inc. Antimicrobial nitric oxide compositions
US8613742B2 (en) 2010-01-29 2013-12-24 Plasma Surgical Investments Limited Methods of sealing vessels using plasma
US9089319B2 (en) 2010-07-22 2015-07-28 Plasma Surgical Investments Limited Volumetrically oscillating plasma flows
US20120107423A1 (en) 2010-11-01 2012-05-03 Ino Therapeutics Llc Methods of Using Inhaled Nitric Oxide Gas for Treatment of Acute Respiratory Distress Syndrome
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
US9289495B2 (en) 2010-12-29 2016-03-22 Strategic Science & Technologies, Llc Systems and methods for treatment of allergies and other indications
ES2811515T3 (es) 2010-12-29 2021-03-12 Strategic Science & Tech Llc Tratamiento de disfunción eréctil y otras indicaciones
WO2012118819A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same
JP2014508166A (ja) 2011-03-17 2014-04-03 トランスダーマル バイオテクノロジ インコーポレーテッド 局所的一酸化窒素システム及びその使用方法
EP2691087A2 (de) 2011-03-31 2014-02-05 László Gábor Szabó Pharmazeutische zusammensetzung mit no, verfahren zu ihrer herstellung und verwendung
WO2013006613A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Methods of manufacturing topical compositions and apparatus for same
BR112014000178A2 (pt) 2011-07-05 2017-02-07 Novan Inc composições tópicas
WO2013085784A1 (en) * 2011-12-05 2013-06-13 Nioxx Llc Compositions and methods for topical nitric oxide generation
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
JP2015518854A (ja) 2012-05-23 2015-07-06 セリックスビオ プライヴェート リミテッド 多発性硬化症の治療のための組成物および方法
SG11201407319YA (en) 2012-05-23 2014-12-30 Cellix Bio Private Ltd Compositions and methods for treatment of inflammatory bowel disease
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
CN103690490B (zh) * 2012-08-23 2017-11-17 尼奥克斯(文莱)控股有限公司 基于微囊化化学试剂延时产生一氧化氮的系统和方法
US20140065090A1 (en) * 2012-08-31 2014-03-06 W. L. Gore & Associates, Inc. Reactive Oxidative Species Generating Materials and Methods of Use
US9259435B2 (en) 2012-08-31 2016-02-16 W. L. Gore & Associates, Inc. Reactive oxidative species generating materials and methods of use
US8871254B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
US8871257B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
US8871261B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Cancer treatments and compositions for use thereof
US8871259B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Techniques and systems for treatment of neuropathic pain and other indications
US8871262B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Compositions and methods for treatment of osteoporosis and other indications
US8871258B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment and prevention of learning and memory disorders
US8871255B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment of skin and soft tissue infection with nitric oxide
US8871260B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and compositions for muscular and neuromuscular diseases
US8871256B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and systems for treatment of inflammatory diseases with nitric oxide
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
US9393265B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9849160B2 (en) 2013-03-13 2017-12-26 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US20140271731A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9687520B2 (en) 2013-03-13 2017-06-27 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9320758B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9387159B2 (en) 2013-03-13 2016-07-12 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9339457B2 (en) 2013-03-13 2016-05-17 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9241899B2 (en) 2013-03-13 2016-01-26 Transdermal Biotechnology, Inc. Topical systems and methods for treating sexual dysfunction
US9314417B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US20140271937A1 (en) * 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9295636B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9320706B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9295637B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Compositions and methods for affecting mood states
US9295647B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9724419B2 (en) 2013-03-13 2017-08-08 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9750787B2 (en) * 2013-03-13 2017-09-05 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9314423B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Hair treatment systems and methods using peptides and other compositions
US20140271938A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9314433B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9314422B2 (en) * 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9393264B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
KR102321169B1 (ko) 2013-08-08 2021-11-02 노반, 인크. 국소 조성물 및 그의 사용 방법
CN106456666A (zh) 2014-01-10 2017-02-22 Ino治疗有限责任公司 使用吸入性一氧化氮气体来治疗儿童的急性呼吸窘迫综合征的方法
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
ES2807200T3 (es) 2014-07-11 2021-02-22 Novan Inc Composiciones antivirales tópicas y procedimientos de uso de las mismas
EP3177262A4 (de) 2014-08-08 2018-04-18 Novan Inc. Topische emulsionen
WO2016027163A1 (en) * 2014-08-18 2016-02-25 Bovicor Pharmatech Inc. Nitric oxide treatment of mammary tissue
CA2976314C (en) 2014-09-26 2021-02-23 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological disorders
CN107207403A (zh) 2014-09-29 2017-09-26 塞尔利克斯生物私人有限公司 用于治疗多发性硬化的组合物和方法
CA2965449C (en) 2014-10-27 2020-11-10 Cellix Bio Private Limited Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis
WO2016067297A1 (en) 2014-10-27 2016-05-06 Cellix Bio Private Limited Salts of valproic acid with piperazine, ethylenediamine, lysine and/or eicosapentaenoic ecid (epa) amine derivatives for the treatment of epilepsy
WO2016077386A1 (en) * 2014-11-10 2016-05-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Topical sodium nitrite formulation
SG11201704282UA (en) 2014-12-01 2017-06-29 Cellix Bio Private Ltd Compositions and methods for the treatment of multiple sclerosis
CN107873024A (zh) 2015-02-09 2018-04-03 塞尔利克斯生物私人有限公司 用于治疗粘膜炎的组合物和方法
ITUB20154719A1 (it) 2015-10-21 2017-04-21 Glano Tech Ltd Formulazione per il rilascio di ossido nitrico
US10052348B2 (en) 2016-01-27 2018-08-21 Syk Technologies, Llc Nitric oxide topical application apparatus and methods
WO2017151905A1 (en) 2016-03-02 2017-09-08 Novan, Inc. Compositions for treating inflammation and methods of treating the same
EP3442502A4 (de) 2016-04-13 2019-11-06 Novan, Inc. Zusammensetzungen, systeme, kits und verfahren zur behandlung von infektionen
US11173235B2 (en) 2016-07-15 2021-11-16 Cook Regentec Llc Nitrite eluting devices and methods of use thereof
RU2751770C2 (ru) 2016-08-11 2021-07-16 Селликс Био Прайвет Лимитед Композиции и способы лечения синдрома раздраженного кишечника
US11643419B2 (en) 2016-10-04 2023-05-09 Cellix Bio Private Limited Compositions and methods for the treatment of xerostomia
EP3554494A4 (de) 2016-12-19 2021-02-17 Cellixbio Private Limited Zusammensetzungen und verfahren zur behandlung von entzündungen
ES2965705T3 (es) * 2017-02-09 2024-04-16 Noxsano Inc Composiciones generadoras de gasotransmisor electroquímico y métodos de utilización de las mismas, y apósitos y sistemas de tratamiento que las incorporan
JP2020528900A (ja) 2017-07-27 2020-10-01 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 体脂肪低減のためのプロスタサイクリン受容体アゴニスト
CN108096297B (zh) * 2017-10-11 2020-12-18 河北京鼎生物医药科技有限公司 包含微囊化的菠菜萃取物和酸性微囊化粉末的一氧化氮延时释放系统和成套用品
CN108096296B (zh) * 2017-10-11 2020-10-16 河北京鼎生物医药科技有限公司 基于菠菜萃取物的微胶囊化粉末和酸性凝胶延长产生一氧化氮的系统和用品
KR102003876B1 (ko) * 2017-11-01 2019-10-04 경희대학교 산학협력단 에멀젼 타입의 유중수형 발기부전 개선용 조성물
JP7038437B2 (ja) 2017-11-17 2022-03-18 セリックス バイオ プライヴェート リミテッド 眼障害及び皮膚疾患の処置のための化合物、組成物、及び方法
CA3081553C (en) 2017-11-17 2022-11-15 Cellix Bio Private Limited Compositions and methods for the treatment of eye disorders
JP2021506958A (ja) 2017-12-13 2021-02-22 オンクォリティ ファーマシューティカルズ チャイナ エルティーディーＯｎｑｕａｌｉｔｙ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｃｈｉｎａ Ｌｔｄ． Ｅｇｆｒ阻害に関連する疾患を予防又は治療する方法
US11472705B2 (en) 2018-03-13 2022-10-18 Sanotize Research And Development Corp. Nitric oxide releasing compositions
US10716805B2 (en) * 2018-03-19 2020-07-21 Glanotech Limited Formulation for release of nitric oxide
EP3782618A4 (de) 2018-04-16 2022-01-26 OnQuality Pharmaceuticals China Ltd. Verfahren zur vorbeugung oder behandlung von nebenwirkungen einer krebstherapie
WO2020227367A1 (en) * 2019-05-06 2020-11-12 Pneuma Nitric Oxide, Llc Nitric oxide compositions and topical uses thereof
JP2023510662A (ja) 2019-06-04 2023-03-15 サーティー レスピラトリー リミテッド 窒素酸化物を生成するための方法および組成物、ならびに気道を介して窒素酸化物を送達するためのそれらの使用
AU2020286677A1 (en) 2019-06-04 2021-12-09 Thirty Holdings Limited Methods and compositions for generating nitric oxide and uses thereof
BR112022005166A2 (pt) 2019-10-07 2022-06-14 Insense Ltd Composição de aplicação à pele
CN115884758A (zh) 2020-04-23 2023-03-31 三十呼吸有限公司 用于治疗SARS-CoV和SARS-CoV-2的一氧化氮或释放一氧化氮的组合物
US20230172973A1 (en) 2020-04-23 2023-06-08 Thirty Respiratory Limited Methods and compositions for treating and combatting tuberculosis
CA3191050A1 (en) 2020-08-28 2022-03-03 Nikolay Suslov Systems, methods, and devices for generating predominantly radially expanded plasma flow

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2054661A1 (en) * 1970-11-06 1972-05-10 Badische Anilin & Soda Fabrik AG, 6700 Ludwigshafen N-nitrosa-n-aryl-hydroxylamines prepn - from nitrosa-arenes and nitrogen oxide
GB1322812A (en) * 1971-02-04 1973-07-11 Ilford Ltd Photographic materials
US4535154A (en) * 1981-07-13 1985-08-13 United States Of America Reductive destruction of nitrosamines, hydrazines, nitramines, azo- and azoxy-compounds
US4954526A (en) * 1989-02-28 1990-09-04 The United States Of America As Represented By The Department Of Health And Human Services Stabilized nitric oxide - primary amine complexes useful as cardiovascular agents
US5208233A (en) * 1989-09-15 1993-05-04 The United States Of America As Represented By The Department Of Health And Human Services Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
US5039705A (en) * 1989-09-15 1991-08-13 The United States Of America As Represented By The Department Of Health And Human Services Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
US5212204A (en) * 1989-10-18 1993-05-18 The United States Of America As Represented By The Department Of Health And Human Services Antihypertensive compositions and use thereof
US5683668A (en) * 1990-09-20 1997-11-04 The United States Of America As Represented By The Department Of Health And Human Services Method of generating nitric oxide gas using nitric oxide complexes
US5155137A (en) * 1990-09-20 1992-10-13 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complexes of nitric oxide with polyamines
US5185376A (en) * 1991-09-24 1993-02-09 The United States Of America As Represented By The Department Of Health And Human Services Therapeutic inhibition of platelet aggregation by nucleophile-nitric oxide complexes and derivatives thereof
DK0693924T4 (da) * 1993-02-22 2008-08-04 Abraxis Bioscience Inc Fremgangsmåde til (in vivo) levering af biologiske materialer og sammensætninger, der er egnede dertil
US5840759A (en) * 1993-10-08 1998-11-24 The United States Of America As Represented By The Department Of Health And Human Services Use of nitric oxide releasing compounds to protect noncancerous cells from chemotherapeutic agents
ES2149338T3 (es) * 1993-11-02 2000-11-01 Us Health Utilizacion de compuestos que liberan oxido nitrico para la fabricacion de un medicamento destinado al tratamiento de lesiones por reperfusion isquemica.
US5519020A (en) * 1994-10-28 1996-05-21 The University Of Akron Polymeric wound healing accelerators
US5648101A (en) * 1994-11-14 1997-07-15 Tawashi; Rashad Drug delivery of nitric oxide
US5698738A (en) * 1995-05-15 1997-12-16 Board Of Regents, The University Of Texas System N-nitroso-N-substituted hydroxylamines as nitric oxide donors
US5726209A (en) * 1995-06-07 1998-03-10 Alliance Pharmaceutical Corp. Liquid fluorocarbon emulsion as a vascular nitric oxide reservoir
SE9700617D0 (sv) * 1997-02-21 1997-02-21 Kjell Alving New composition
US5888528A (en) * 1997-05-19 1999-03-30 Bernard Technologies, Inc. Sustained release biocidal powders
US6103275A (en) * 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide

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EP1283724A1 (de) 2003-02-19
CA2410990A1 (en) 2001-11-29
CA2410990C (en) 2011-08-02
US7048951B1 (en) 2006-05-23
AU2000250426B2 (en) 2005-06-30
AU2000250426A1 (en) 2002-02-21
US6103275A (en) 2000-08-15
AU5042600A (en) 2001-12-03
EP1283724B1 (de) 2009-05-06
ATE430584T1 (de) 2009-05-15

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