DE60111267D1 - Implantierbare vorrichtung, enthaltend lebende zellen - Google Patents

Implantierbare vorrichtung, enthaltend lebende zellen

Info

Publication number
DE60111267D1
DE60111267D1 DE60111267T DE60111267T DE60111267D1 DE 60111267 D1 DE60111267 D1 DE 60111267D1 DE 60111267 T DE60111267 T DE 60111267T DE 60111267 T DE60111267 T DE 60111267T DE 60111267 D1 DE60111267 D1 DE 60111267D1
Authority
DE
Germany
Prior art keywords
implantable device
living cells
device containing
containing living
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60111267T
Other languages
English (en)
Other versions
DE60111267T2 (de
Inventor
Pnina Vardi
Yossi Gross
Konstantin Bloch
Daria Bloch
Nizza Boukobza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beta O2 Technologies Ltd
Original Assignee
Beta O2 Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beta O2 Technologies Ltd filed Critical Beta O2 Technologies Ltd
Application granted granted Critical
Publication of DE60111267D1 publication Critical patent/DE60111267D1/de
Publication of DE60111267T2 publication Critical patent/DE60111267T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
DE60111267T 2000-01-12 2001-01-12 Implantierbare vorrichtung, enthaltend lebende zellen Expired - Lifetime DE60111267T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL134009A IL134009A (en) 2000-01-12 2000-01-12 Transplant device
PCT/IL2001/000031 WO2001050983A1 (en) 2000-01-12 2001-01-12 Implantable device

Publications (2)

Publication Number Publication Date
DE60111267D1 true DE60111267D1 (de) 2005-07-07
DE60111267T2 DE60111267T2 (de) 2005-10-27

Family

ID=11073701

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60111267T Expired - Lifetime DE60111267T2 (de) 2000-01-12 2001-01-12 Implantierbare vorrichtung, enthaltend lebende zellen
DE60131913T Expired - Lifetime DE60131913T2 (de) 2000-01-12 2001-01-12 Implantierbare Vorrichtung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60131913T Expired - Lifetime DE60131913T2 (de) 2000-01-12 2001-01-12 Implantierbare Vorrichtung

Country Status (9)

Country Link
US (1) US7892222B2 (de)
EP (2) EP1645243B1 (de)
AT (2) ATE296589T1 (de)
AU (1) AU2544201A (de)
DE (2) DE60111267T2 (de)
DK (2) DK1351623T3 (de)
ES (2) ES2299916T3 (de)
IL (1) IL134009A (de)
WO (1) WO2001050983A1 (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8012500B2 (en) * 2000-01-01 2011-09-06 Beta-O2 Technologies Ltd. Implantable device
JP2003190259A (ja) * 2001-12-28 2003-07-08 Hisako Ogawara 人工臓器用チャンバー
US8066659B2 (en) 2004-06-15 2011-11-29 Ceramatec, Inc. Apparatus and method for treating and dispensing a material into tissue
US8777889B2 (en) * 2004-06-15 2014-07-15 Ceramatec, Inc. Apparatus and method for administering a therapeutic agent into tissue
US7615030B2 (en) * 2003-10-06 2009-11-10 Active O, Llc Apparatus and method for administering a therapeutic agent into tissue
EP1935442B1 (de) * 2003-10-06 2010-08-04 Activeo, LLC Implantierbare Vorrichtung zur Verabreichung eines therapeutischen Mittels
US20050153309A1 (en) 2003-12-22 2005-07-14 David Hoon Method and apparatus for in vivo surveillance of circulating biological components
EP2532356A1 (de) 2004-07-14 2012-12-12 Glusense Ltd. Implantierbare Stromquellen und -Sensoren
US8353906B2 (en) 2005-08-01 2013-01-15 Ceramatec, Inc. Electrochemical probe and method for in situ treatment of a tissue
US8273075B2 (en) * 2005-12-13 2012-09-25 The Invention Science Fund I, Llc Osmotic pump with remotely controlled osmotic flow rate
US20070106275A1 (en) 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Reaction device controlled by RF control signal
US7942867B2 (en) 2005-11-09 2011-05-17 The Invention Science Fund I, Llc Remotely controlled substance delivery device
US8992511B2 (en) 2005-11-09 2015-03-31 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US9067047B2 (en) 2005-11-09 2015-06-30 The Invention Science Fund I, Llc Injectable controlled release fluid delivery system
US8936590B2 (en) * 2005-11-09 2015-01-20 The Invention Science Fund I, Llc Acoustically controlled reaction device
US8083710B2 (en) * 2006-03-09 2011-12-27 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US8273071B2 (en) * 2006-01-18 2012-09-25 The Invention Science Fund I, Llc Remote controller for substance delivery system
TW200734462A (en) 2006-03-08 2007-09-16 In Motion Invest Ltd Regulating stem cells
US20080140057A1 (en) * 2006-03-09 2008-06-12 Searete Llc, A Limited Liability Corporation Of State Of The Delaware Injectable controlled release fluid delivery system
EP2004241B1 (de) * 2006-03-28 2013-08-07 Glusense Ltd. Implantierbarer sensor
US20100047311A1 (en) * 2006-11-22 2010-02-25 Beta O2 Technologies Ltd. Protecting algae from body fluids
ES2659988T3 (es) * 2006-11-28 2018-03-20 Beta O2 Technologies Ltd. Suministro de oxígeno para el transplante celular y la vascularización
US20100196439A1 (en) * 2006-12-22 2010-08-05 Medtronic, Inc. Angiogenesis Mechanism and Method, and Implantable Device
AU2008214423A1 (en) * 2007-02-02 2008-08-14 Converge Biotech Inc. Therapeutic hybrid implantable devices
US8821431B2 (en) * 2007-09-07 2014-09-02 Beta O2 Technologies Ltd. Air gap for supporting cells
US20090182303A1 (en) * 2008-01-14 2009-07-16 Steven Walak Targeted Therapeutic Agent Release for Weight Loss Therapy
WO2010032242A1 (en) * 2008-09-17 2010-03-25 Beta O2 Technologies Ltd. Optimization of alginate encapsulation of islets for transplantation
US8043271B2 (en) 2008-11-26 2011-10-25 Beta 02 Technologies Ltd. Apparatus for transportation of oxygen to implanted cells
US20100160749A1 (en) * 2008-12-24 2010-06-24 Glusense Ltd. Implantable optical glucose sensing
WO2010091074A2 (en) * 2009-02-03 2010-08-12 Purdue Research Foundation Method and apparatus for improving local hypoxicity for enhanced therapy
US9357764B2 (en) 2009-06-18 2016-06-07 Giner, Inc. System for fluid perfusion of biological matter comprising tissue
US10091985B2 (en) * 2009-06-18 2018-10-09 Giner, Inc. Perfusing an organ with an in situ generated gas
US8784389B2 (en) * 2009-08-31 2014-07-22 Beta-O2 Technologies Ltd. Oxygen supply for implantable medical device
EP2389958A1 (de) 2010-03-22 2011-11-30 Technische Universität Klinikum Rechts der Isar Verwendung photosynthetischer Gerüste bei der Gewebekonstruktion
WO2011154941A2 (en) 2010-06-07 2011-12-15 Beta-O2 Technologies Ltd. Multiple-layer immune barrier for donor cells
JP2012031070A (ja) * 2010-07-28 2012-02-16 Otsuka Pharmaceut Factory Inc 組織の保存方法、及び組織保存装置
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
WO2013018179A1 (ja) * 2011-07-29 2013-02-07 トヨタ自動車株式会社 リチウムイオン二次電池およびその製造方法
US9919140B2 (en) 2012-10-05 2018-03-20 University Of Southern California Implantable oxygenator with self-contained electrolyte
WO2014102743A1 (en) * 2012-12-28 2014-07-03 Glusense, Ltd. Apparatus for facilitating cell growth in an implantable sensor
AU2014326794B2 (en) 2013-09-24 2019-03-21 Giner, Inc. System for gas treatment of a cell implant
US9950151B2 (en) * 2014-03-27 2018-04-24 Beta-O2 Technologies Ltd. Implantable medical devices
EP3188796B1 (de) 2014-09-03 2021-12-22 Symbiox, Inc. Photosynthetische zellstoffe
CN106999118B (zh) 2014-10-13 2020-07-17 葡萄糖传感器公司 分析物感测装置
WO2017183030A1 (en) 2016-04-20 2017-10-26 Glusense Ltd. Fret-based glucose-detection molecules
CN109561890A (zh) 2016-06-09 2019-04-02 海马切克公司 用于检测和可逆地捕获活体内体液中的细胞的收集器
EP3534692A4 (de) * 2016-11-03 2020-06-17 Arizona Board of Regents on behalf of the University of Arizona Verfahren und systeme zur echtzeitbeurteilung von zellen in verkapselungsvorrichtungen vor und nach der transplantation
US11446133B2 (en) 2016-11-03 2022-09-20 Arizona Board Of Regents On Behalf Of The University Of Arizona Stacked tissue encapsulation device systems with or without oxygen delivery
KR20230037059A (ko) * 2016-11-03 2023-03-15 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 외부 산소 전달을 수반 또는 비-수반하는 산소 센서가 구비된 캡슐화 장치 시스템
BR112019009712A2 (pt) 2016-11-15 2019-08-13 Giner Life Sciences Inc dispositivo de difusão gasosa percutânea adequado para uso com um implante subcutâneo
KR20190085961A (ko) 2016-11-15 2019-07-19 기너 라이프 사이언시즈, 인크. 자기 조절형 전기 분해 가스 발생기 및 이를 포함하는 이식 시스템
AR111512A1 (es) * 2017-02-23 2019-07-24 Japan Vam & Poval Co Ltd Dispositivo de integración celular o tisular
CA3062412A1 (en) 2017-05-04 2018-11-08 Giner Life Sciences, Inc. Robust, implantable gas delivery device and methods, systems and devices including same
CA3089583A1 (en) * 2018-01-24 2019-08-01 Thomas Jefferson University Biodiffusion chamber
WO2019157421A1 (en) * 2018-02-09 2019-08-15 W. L. Gore & Associates, Inc. Implantable access chamber and associated methods of use
CN113164721B (zh) * 2018-05-14 2024-03-08 杜松子酒有限公司 用于控制到植入的细胞的氧输送的系统和方法
CN112492873A (zh) * 2018-05-15 2021-03-12 输出实验室公司 可植入设备及其使用方法
JP2021523981A (ja) 2018-05-17 2021-09-09 ガイナー ライフ サイエンシズ，インク． リードターミナルとガスポートターミナルとを組み合わせた電解ガス発生装置
EP4236866A1 (de) * 2020-10-30 2023-09-06 Arizona Board of Regents on behalf of the University of Arizona Verfahren und systeme für verkapselungsvorrichtungen zur aufnahme von zellen und mitteln
US20240024089A1 (en) * 2020-12-09 2024-01-25 Cornell University Methods and devices for providing oxygen to encapsulated cells
CN115025037A (zh) * 2022-06-10 2022-09-09 河北大学 一种负载活性小球藻的可分离微针及其制备方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4402694A (en) * 1981-07-16 1983-09-06 Biotek, Inc. Body cavity access device containing a hormone source
US4631053A (en) * 1984-03-19 1986-12-23 Taheri Syde A Oxygenator
US4680268A (en) 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
US5427935A (en) 1987-07-24 1995-06-27 The Regents Of The University Of Michigan Hybrid membrane bead and process for encapsulating materials in semi-permeable hybrid membranes
US5011472A (en) 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
US5101814A (en) 1989-08-11 1992-04-07 Palti Yoram Prof System for monitoring and controlling blood glucose
US5116494A (en) * 1989-08-25 1992-05-26 W. R. Grace & Co.-Conn. Artificial pancreatic perfusion device with temperature sensitive matrix
US5614378A (en) * 1990-06-28 1997-03-25 The Regents Of The University Of Michigan Photobioreactors and closed ecological life support systems and artifificial lungs containing the same
US5713888A (en) * 1990-10-31 1998-02-03 Baxter International, Inc. Tissue implant systems
US5545423A (en) 1991-11-25 1996-08-13 Vivorx, Inc. Cytoprotective, biocompatible, retrievable macrocapsule containment systems for biologically active materials
US5834005A (en) 1992-02-24 1998-11-10 Encelle, Inc. Bioartificial devices and cellular matrices therefor
US5262055A (en) 1992-10-19 1993-11-16 The University Of Utah Implantable and refillable biohybrid artificial pancreas
US5651980A (en) 1994-04-15 1997-07-29 Biohybrid Technologies, Inc. Methods of use of uncoated gel particles
US5529066A (en) * 1994-06-27 1996-06-25 Cb-Carmel Biotechnology Ltd. Implantable capsule for enhancing cell electric signals
US5741334A (en) 1995-06-07 1998-04-21 Circe Biomedical, Inc. Artificial pancreatic perfusion device
WO1997010807A1 (en) 1995-09-22 1997-03-27 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
US5855613A (en) 1995-10-13 1999-01-05 Islet Sheet Medical, Inc. Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change
US6368592B1 (en) 1998-07-17 2002-04-09 Massachusetts Institute Of Technology Method of delivering oxygen to cells by electrolyzing water
US6562616B1 (en) 1999-06-21 2003-05-13 The General Hospital Corporation Methods and devices for cell culturing and organ assist systems
US8012500B2 (en) 2000-01-01 2011-09-06 Beta-O2 Technologies Ltd. Implantable device
US7332330B2 (en) 2001-09-11 2008-02-19 Renamed Biologics, Inc. Device for maintaining vascularization near an implant
CN1291761C (zh) 2002-03-04 2006-12-27 新技术国际交流株式会社 封闭型细胞培养系统
US8532730B2 (en) 2006-10-04 2013-09-10 Dexcom, Inc. Analyte sensor
ES2659988T3 (es) 2006-11-28 2018-03-20 Beta O2 Technologies Ltd. Suministro de oxígeno para el transplante celular y la vascularización
US8821431B2 (en) 2007-09-07 2014-09-02 Beta O2 Technologies Ltd. Air gap for supporting cells

Also Published As

Publication number Publication date
US20040133188A1 (en) 2004-07-08
ATE296589T1 (de) 2005-06-15
EP1645243A3 (de) 2006-05-17
DE60111267T2 (de) 2005-10-27
AU2544201A (en) 2001-07-24
DE60131913T2 (de) 2008-12-04
WO2001050983A1 (en) 2001-07-19
EP1351623A1 (de) 2003-10-15
EP1645243B1 (de) 2007-12-12
IL134009A (en) 2011-07-31
EP1351623B1 (de) 2005-06-01
IL134009A0 (en) 2001-04-30
DE60131913D1 (de) 2008-01-24
DK1351623T3 (da) 2005-09-19
DK1645243T3 (da) 2008-04-21
EP1645243A2 (de) 2006-04-12
US7892222B2 (en) 2011-02-22
ES2299916T3 (es) 2008-06-01
ATE380526T1 (de) 2007-12-15
ES2239662T3 (es) 2005-10-01

Similar Documents

Publication Publication Date Title
ATE296589T1 (de) Implantierbare vorrichtung, enthaltend lebende zellen
DE60040698D1 (de) Stimulationssystem
ATE263354T1 (de) Vorrichtung zur herstellung von kontaktkörpern
DE60136293D1 (de) Vorrichtung zum abliefern von pharmazeutika an das innenohr
WO2006059322A3 (en) Implantable device
DE60116551D1 (de) Elektrodenleitung zur Stimulation von Wirbelsaülen
DE60110980D1 (de) Katheterleitung zur Implantation in den intrathekalen Raum
ATE469670T1 (de) Verbindungsmodul für eine modulare implantierbare medizinische vorrichtung
BRPI0507812A (pt) sistema de microativação, método para a microativação das células epidérmicas, kit, método para montar o dispositivo de microativação e método para a microativação da pele
CA2298597A1 (en) Humidity control device
ATE407620T1 (de) Drahtloses kommunikationssystem
ATE521424T1 (de) Entsorgung von menschlichen überresten
DE60327090D1 (de) Implantierbare medizinische vorrichtung
DE60029824D1 (de) Zahnprothese mit wirkstoffabgabevorrichtung
DE60042252D1 (de) Implantierbare medizinische Vorrichtung
BR9711562A (pt) Dispositivo m-dico para a coloca-Æo de materiais sÄlidos
SE0201321D0 (sv) An implantable medical device and a manufacturing method thereof
IL152630A0 (en) Implantable device
ATE446784T1 (de) Konfiguration implantierter vorrichtungen
WO2002100914A3 (en) Polymeric material, containing a latent acid
SE0303324D0 (sv) Implantat
EP1295611A4 (de) Verbindungen für den transfer von oligonukleotiden(03.01.02)
ZA99535B (en) Oxygen generating device.
DE60234250D1 (de) Vorrichtung zur Zell- bzw. Gewebezüchtung
SE0202319D0 (sv) Arrangemang för att öka tåligheten mot belastning på implantat samt sådant implantat

Legal Events

Date Code Title Description
8364 No opposition during term of opposition