DE60128550D1 - Verfahren und gerät zur automatischen pin-detektion in instrumenten zur erzeugung von mikroarrays - Google Patents
Verfahren und gerät zur automatischen pin-detektion in instrumenten zur erzeugung von mikroarraysInfo
- Publication number
- DE60128550D1 DE60128550D1 DE60128550T DE60128550T DE60128550D1 DE 60128550 D1 DE60128550 D1 DE 60128550D1 DE 60128550 T DE60128550 T DE 60128550T DE 60128550 T DE60128550 T DE 60128550T DE 60128550 D1 DE60128550 D1 DE 60128550D1
- Authority
- DE
- Germany
- Prior art keywords
- pin
- printhead
- pins
- locations
- sensor elements
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0244—Drop counters; Drop formers using pins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00387—Applications using probes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/0059—Sequential processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00693—Means for quality control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
- Y10T436/114998—Automated chemical analysis with conveyance of sample along a test line in a container or rack with treatment or replacement of aspirator element [e.g., cleaning, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/119163—Automated chemical analysis with aspirator of claimed structure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US527892 | 1983-08-30 | ||
US09/527,892 US6878554B1 (en) | 2000-03-20 | 2000-03-20 | Method and apparatus for automatic pin detection in microarray spotting instruments |
PCT/US2001/007721 WO2001071035A2 (en) | 2000-03-20 | 2001-03-12 | Method and apparatus for automatic pin detection in microarray spotting instruments |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60128550D1 true DE60128550D1 (de) | 2007-07-05 |
DE60128550T2 DE60128550T2 (de) | 2007-12-06 |
Family
ID=24103372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60128550T Expired - Lifetime DE60128550T2 (de) | 2000-03-20 | 2001-03-12 | Verfahren und gerät zur automatischen pin-detektion in instrumenten zur erzeugung von mikroarrays |
Country Status (7)
Country | Link |
---|---|
US (2) | US6878554B1 (de) |
EP (1) | EP1265711B1 (de) |
JP (1) | JP2004515744A (de) |
AT (1) | ATE362804T1 (de) |
CA (1) | CA2404099C (de) |
DE (1) | DE60128550T2 (de) |
WO (1) | WO2001071035A2 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6893877B2 (en) * | 1998-01-12 | 2005-05-17 | Massachusetts Institute Of Technology | Methods for screening substances in a microwell array |
US20020151040A1 (en) | 2000-02-18 | 2002-10-17 | Matthew O' Keefe | Apparatus and methods for parallel processing of microvolume liquid reactions |
US6878554B1 (en) * | 2000-03-20 | 2005-04-12 | Perkinelmer Las, Inc. | Method and apparatus for automatic pin detection in microarray spotting instruments |
US6749812B2 (en) * | 2000-06-26 | 2004-06-15 | Vistalab Technologies | Automatic pipette detipping |
EP1390147A4 (de) * | 2001-05-03 | 2006-06-07 | Affymetrix Inc | System und verfahren zum betupfen von mikroarrays mit hohem durchsatz |
US7402286B2 (en) | 2001-06-27 | 2008-07-22 | The Regents Of The University Of California | Capillary pins for high-efficiency microarray printing device |
US6855538B2 (en) | 2001-06-27 | 2005-02-15 | The Regents Of The University Of California | High-efficiency microarray printing device |
JP4392157B2 (ja) * | 2001-10-26 | 2009-12-24 | パナソニック電工株式会社 | 配線板用シート材及びその製造方法、並びに多層板及びその製造方法 |
US6759012B2 (en) * | 2001-11-05 | 2004-07-06 | Genetix Limited | Pin holder for a microarraying apparatus |
EP1323465A1 (de) | 2001-12-31 | 2003-07-02 | Corning Incorporated | Flexibler Druckkopf fuer Matrix von hoher dichte mit Einrichtung und Methode zur Ausrrichtung von Pinplatte, Behältern und Substrat zueinander |
JP2003329680A (ja) * | 2002-05-10 | 2003-11-19 | Hitachi Software Eng Co Ltd | スポットピン、スポッティング装置及び生体分子スポット方法 |
US8277753B2 (en) * | 2002-08-23 | 2012-10-02 | Life Technologies Corporation | Microfluidic transfer pin |
US7208124B2 (en) * | 2002-11-19 | 2007-04-24 | Genetix Limited | Microarraying process and apparatus |
WO2004074818A2 (en) | 2002-12-20 | 2004-09-02 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
US20030166263A1 (en) * | 2002-12-30 | 2003-09-04 | Haushalter Robert C. | Microfabricated spotting apparatus for producing low cost microarrays |
US20040151635A1 (en) * | 2003-01-31 | 2004-08-05 | Leproust Eric M. | Array fabrication using deposited drop splat size |
DK2322278T3 (en) * | 2003-10-24 | 2017-04-10 | Aushon Biosystems Inc | Apparatus and method for dispensing liquid, semi-solid and solid samples |
JP4542345B2 (ja) * | 2004-01-15 | 2010-09-15 | シスメックス株式会社 | 分析装置 |
CA2559171A1 (en) | 2004-03-12 | 2005-09-29 | Biotrove, Inc. | Nanoliter array loading |
US7875463B2 (en) * | 2004-03-26 | 2011-01-25 | Agilent Technologies, Inc. | Generalized pulse jet ejection head control model |
US20050261839A1 (en) * | 2004-05-18 | 2005-11-24 | Shinde Ninad A | Smart substance processing device and a system and method of monitoring thereof |
WO2006094049A2 (en) * | 2005-03-01 | 2006-09-08 | Parallel Synthesis Technologies, Inc. | Polymeric fluid transfer and printing devices |
EP1859284A1 (de) * | 2005-03-17 | 2007-11-28 | Kuoni, A. | Vorrichtung und verfahren zum aufbringen einer vielzahl von mikrotröpfchen auf ein substrat |
US20080003667A1 (en) * | 2006-05-19 | 2008-01-03 | Affymetrix, Inc. | Consumable elements for use with fluid processing and detection systems |
US9682372B2 (en) | 2008-06-19 | 2017-06-20 | Carterra, Inc. | Tip overlay for continuous flow spotting apparatus |
US20100248981A1 (en) * | 2009-03-27 | 2010-09-30 | Affymetrix, Inc. | System and methods for processing microarrays |
WO2011008872A1 (en) * | 2009-07-14 | 2011-01-20 | Amfit, Inc. | Electrostatic sensor device and matrix |
DE102010054581A1 (de) * | 2010-12-15 | 2012-06-21 | Bruker Daltonik Gmbh | Probenpräparation für die Ionisierung mit matrixunterstützter Laserdesorption |
WO2014134228A1 (en) * | 2013-02-26 | 2014-09-04 | The Regents Of The University Of California | Multiplex chemotyping microarray (mcm) system and methods |
US10288633B2 (en) | 2015-06-26 | 2019-05-14 | Abbott Laboratories | Reaction vessel moving member for moving reaction vessels from a processing track to a rotating device in a diagnostic analyzer |
CN108027379B (zh) | 2015-06-26 | 2021-07-23 | 雅培实验室 | 用于诊断分析设备的反应容器交换装置 |
US9913598B2 (en) * | 2015-10-17 | 2018-03-13 | Igor Landau | Noninvasive nondisruptive assessment of eyelid dynamics by means of Eddy-current no-touch sensors |
DE102016215240B3 (de) * | 2016-08-16 | 2017-10-12 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Mikrodosiereinrichtung und automatisches Mikrodosierverfahren |
Family Cites Families (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5895262A (ja) * | 1981-12-01 | 1983-06-06 | Toshiba Corp | 誠試薬分注装置 |
FR2606885B1 (fr) | 1986-11-14 | 1989-08-04 | Abx Sarl | Dispositif de nettoyage d'une aiguille de prelevement d'un liquide |
US4745681A (en) | 1987-04-22 | 1988-05-24 | International Business Machines Corporation | Controlled pin insertion using airflow sensing and active feedback |
US5055263A (en) | 1988-01-14 | 1991-10-08 | Cyberlab, Inc. | Automated pipetting system |
US5306510A (en) | 1988-01-14 | 1994-04-26 | Cyberlab, Inc. | Automated pipetting system |
US5700637A (en) | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
US5133373A (en) | 1989-12-01 | 1992-07-28 | Akzo N.V. | Apparatus and method for cleaning reagent delivery probes |
US5141871A (en) | 1990-05-10 | 1992-08-25 | Pb Diagnostic Systems, Inc. | Fluid dispensing system with optical locator |
US5408891A (en) | 1992-12-17 | 1995-04-25 | Beckman Instruments, Inc. | Fluid probe washing apparatus and method |
US5525515A (en) | 1993-02-03 | 1996-06-11 | Blattner; Frederick R. | Process of handling liquids in an automated liquid handling apparatus |
CA2132270A1 (en) | 1993-10-28 | 1995-04-29 | Erich Lerch | Automatic pipetting apparatus having a cleaning device |
US5411065A (en) | 1994-01-10 | 1995-05-02 | Kvm Technologies, Inc. | Liquid specimen transfer apparatus and method |
US6015880A (en) | 1994-03-16 | 2000-01-18 | California Institute Of Technology | Method and substrate for performing multiple sequential reactions on a matrix |
US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
US6017496A (en) | 1995-06-07 | 2000-01-25 | Irori | Matrices with memories and uses thereof |
US5603342A (en) | 1995-06-29 | 1997-02-18 | Coulter Corporation | Apparatus for cleaning a fluid sample probe |
US5843378A (en) * | 1995-09-05 | 1998-12-01 | Ljl Biosystems | Method of producing a probe for aspirating and dispensing probe having surface sensing capability |
GB9522056D0 (en) * | 1995-10-27 | 1996-01-03 | Dynatech Med Prod Ltd | Level sensor and washer unit |
US5827744A (en) | 1995-11-06 | 1998-10-27 | Dade International Inc. | Method and apparatus for cleaning a liquid dispensing probe |
GB2310006B (en) | 1995-12-01 | 2000-01-12 | Genetix Ltd | Pneumatic actuator |
JP3645340B2 (ja) * | 1995-12-18 | 2005-05-11 | 北陽電機株式会社 | フラットパッケージのピン曲がりの検出装置 |
US6083762A (en) | 1996-05-31 | 2000-07-04 | Packard Instruments Company | Microvolume liquid handling system |
US5770151A (en) | 1996-06-05 | 1998-06-23 | Molecular Dynamics, Inc. | High-speed liquid deposition device for biological molecule array formation |
US6024925A (en) | 1997-01-23 | 2000-02-15 | Sequenom, Inc. | Systems and methods for preparing low volume analyte array elements |
WO1998029736A1 (en) | 1996-12-31 | 1998-07-09 | Genometrix Incorporated | Multiplexed molecular analysis apparatus and method |
CA2278146A1 (en) | 1997-01-17 | 1998-07-23 | John Gerald Gleason | Apparatus and process for arraying beads |
US5897837A (en) | 1997-02-06 | 1999-04-27 | Toa Medical Electronics Co., Ltd. | Dispensing device and Immunoassay apparatus using the same |
US5895915A (en) | 1997-07-24 | 1999-04-20 | General Scanning, Inc. | Bi-directional scanning system with a pixel clock system |
US6228659B1 (en) | 1997-10-31 | 2001-05-08 | PE Corporation (“NY”) | Method and apparatus for making arrays |
US5922617A (en) | 1997-11-12 | 1999-07-13 | Functional Genetics, Inc. | Rapid screening assay methods and devices |
US6101946A (en) | 1997-11-21 | 2000-08-15 | Telechem International Inc. | Microarray printing device including printing pins with flat tips and exterior channel and method of manufacture |
US5957167A (en) | 1997-12-18 | 1999-09-28 | Pharmacopeia, Inc. | Article for dispensing small volumes of liquid |
US6063339A (en) | 1998-01-09 | 2000-05-16 | Cartesian Technologies, Inc. | Method and apparatus for high-speed dot array dispensing |
US6269846B1 (en) | 1998-01-13 | 2001-08-07 | Genetic Microsystems, Inc. | Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays |
US6428752B1 (en) | 1998-05-14 | 2002-08-06 | Affymetrix, Inc. | Cleaning deposit devices that form microarrays and the like |
US6131512A (en) * | 1998-02-03 | 2000-10-17 | Agfa-Gevaert, N.V. | Printing master comprising strain gauges |
AU2775799A (en) | 1998-02-20 | 1999-09-06 | Cartesian Technologies, Inc. | Methods for microfluidic aspirating and dispensing |
US6235473B1 (en) * | 1998-07-02 | 2001-05-22 | Orchid Biosciences, Inc. | Gene pen devices for array printing |
WO2000001798A2 (en) | 1998-07-07 | 2000-01-13 | Cartesian Technologies, Inc. | Tip design and random access array for microfluidic transfer |
US6309891B1 (en) | 1998-09-09 | 2001-10-30 | Incyte Genomics, Inc. | Capillary printing systems |
US6039211A (en) | 1998-09-22 | 2000-03-21 | Glaxo Wellcome Inc. | Position triggered dispenser and methods |
US6215894B1 (en) | 1999-02-26 | 2001-04-10 | General Scanning, Incorporated | Automatic imaging and analysis of microarray biochips |
US6245297B1 (en) | 1999-04-16 | 2001-06-12 | Pe Corporation (Ny) | Apparatus and method for transferring small volumes of substances |
US6878554B1 (en) | 2000-03-20 | 2005-04-12 | Perkinelmer Las, Inc. | Method and apparatus for automatic pin detection in microarray spotting instruments |
-
2000
- 2000-03-20 US US09/527,892 patent/US6878554B1/en not_active Expired - Lifetime
-
2001
- 2001-03-12 JP JP2001569414A patent/JP2004515744A/ja active Pending
- 2001-03-12 CA CA2404099A patent/CA2404099C/en not_active Expired - Lifetime
- 2001-03-12 WO PCT/US2001/007721 patent/WO2001071035A2/en active IP Right Grant
- 2001-03-12 AT AT01914791T patent/ATE362804T1/de not_active IP Right Cessation
- 2001-03-12 DE DE60128550T patent/DE60128550T2/de not_active Expired - Lifetime
- 2001-03-12 EP EP01914791A patent/EP1265711B1/de not_active Expired - Lifetime
-
2005
- 2005-04-11 US US11/103,162 patent/US7335338B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2001071035A3 (en) | 2002-06-27 |
WO2001071035A2 (en) | 2001-09-27 |
EP1265711A2 (de) | 2002-12-18 |
US6878554B1 (en) | 2005-04-12 |
ATE362804T1 (de) | 2007-06-15 |
EP1265711B1 (de) | 2007-05-23 |
CA2404099A1 (en) | 2001-09-27 |
DE60128550T2 (de) | 2007-12-06 |
US7335338B2 (en) | 2008-02-26 |
JP2004515744A (ja) | 2004-05-27 |
US20050181510A1 (en) | 2005-08-18 |
CA2404099C (en) | 2010-05-25 |
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