DE602004030902D1 - Biointerface-membranen mit bioaktiven mitteln - Google Patents

Biointerface-membranen mit bioaktiven mitteln

Info

Publication number
DE602004030902D1
DE602004030902D1 DE602004030902T DE602004030902T DE602004030902D1 DE 602004030902 D1 DE602004030902 D1 DE 602004030902D1 DE 602004030902 T DE602004030902 T DE 602004030902T DE 602004030902 T DE602004030902 T DE 602004030902T DE 602004030902 D1 DE602004030902 D1 DE 602004030902D1
Authority
DE
Germany
Prior art keywords
bioactive agents
vivo
biointerface membrane
biointerface membranes
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004030902T
Other languages
English (en)
Inventor
Victoria Carr-Brendel
Mark Tapsak
Dubravka Markovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dexcom Inc
Original Assignee
Dexcom Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34119759&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602004030902(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US10/647,065 external-priority patent/US7192450B2/en
Application filed by Dexcom Inc filed Critical Dexcom Inc
Publication of DE602004030902D1 publication Critical patent/DE602004030902D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/08Methods for forming porous structures using a negative form which is filled and then removed by pyrolysis or dissolution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
DE602004030902T 2003-05-21 2004-05-19 Biointerface-membranen mit bioaktiven mitteln Active DE602004030902D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US47267303P 2003-05-21 2003-05-21
US10/647,065 US7192450B2 (en) 2003-05-21 2003-08-22 Porous membranes for use with implantable devices
US54472204P 2004-02-12 2004-02-12
PCT/US2004/015846 WO2005025634A2 (en) 2003-05-21 2004-05-19 Biointerface membranes incorporating bioactive agents

Publications (1)

Publication Number Publication Date
DE602004030902D1 true DE602004030902D1 (de) 2011-02-17

Family

ID=34119759

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004030902T Active DE602004030902D1 (de) 2003-05-21 2004-05-19 Biointerface-membranen mit bioaktiven mitteln

Country Status (6)

Country Link
US (5) US7875293B2 (de)
EP (1) EP1624908B8 (de)
JP (1) JP2006525853A (de)
AT (1) ATE494018T1 (de)
DE (1) DE602004030902D1 (de)
WO (1) WO2005025634A2 (de)

Families Citing this family (374)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593852A (en) * 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US7657297B2 (en) * 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
US7192450B2 (en) * 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6134461A (en) * 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
US6932894B2 (en) * 2001-05-15 2005-08-23 Therasense, Inc. Biosensor membranes composed of polymers containing heterocyclic nitrogens
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US6702857B2 (en) * 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US7828728B2 (en) * 2003-07-25 2010-11-09 Dexcom, Inc. Analyte sensor
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US20060258761A1 (en) * 2002-05-22 2006-11-16 Robert Boock Silicone based membranes for use in implantable glucose sensors
US7226978B2 (en) * 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
EP2322798A1 (de) 2002-10-09 2011-05-18 Abbott Diabetes Care Inc. Vorrichtung und Verfahren zur Förderung medizinischer Fluide unter Verwendung einer Gedächtnislegierung
US7993108B2 (en) 2002-10-09 2011-08-09 Abbott Diabetes Care Inc. Variable volume, shape memory actuated insulin dispensing pump
US7727181B2 (en) * 2002-10-09 2010-06-01 Abbott Diabetes Care Inc. Fluid delivery device with autocalibration
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US8771183B2 (en) 2004-02-17 2014-07-08 Abbott Diabetes Care Inc. Method and system for providing data communication in continuous glucose monitoring and management system
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
US7134999B2 (en) * 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US7587287B2 (en) 2003-04-04 2009-09-08 Abbott Diabetes Care Inc. Method and system for transferring analyte test data
US7679407B2 (en) 2003-04-28 2010-03-16 Abbott Diabetes Care Inc. Method and apparatus for providing peak detection circuitry for data communication systems
US7875293B2 (en) 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US8460243B2 (en) * 2003-06-10 2013-06-11 Abbott Diabetes Care Inc. Glucose measuring module and insulin pump combination
US8071028B2 (en) * 2003-06-12 2011-12-06 Abbott Diabetes Care Inc. Method and apparatus for providing power management in data communication systems
US7695239B2 (en) * 2003-07-14 2010-04-13 Fortrend Engineering Corporation End effector gripper arms having corner grippers which reorient reticle during transfer
US7722536B2 (en) 2003-07-15 2010-05-25 Abbott Diabetes Care Inc. Glucose measuring device integrated into a holster for a personal area network device
WO2005010518A1 (en) * 2003-07-23 2005-02-03 Dexcom, Inc. Rolled electrode array and its method for manufacture
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US7761130B2 (en) * 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
JP4708342B2 (ja) 2003-07-25 2011-06-22 デックスコム・インコーポレーテッド 埋設可能な装置に用いる酸素増大膜システム
US8282549B2 (en) 2003-12-09 2012-10-09 Dexcom, Inc. Signal processing for continuous analyte sensor
US20050176136A1 (en) * 2003-11-19 2005-08-11 Dexcom, Inc. Afinity domain for analyte sensor
US20070173709A1 (en) * 2005-04-08 2007-07-26 Petisce James R Membranes for an analyte sensor
JP2007500336A (ja) * 2003-07-25 2007-01-11 デックスコム・インコーポレーテッド 電気化学センサーに用いる電極システム
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7651596B2 (en) 2005-04-08 2010-01-26 Dexcom, Inc. Cellulosic-based interference domain for an analyte sensor
US7467003B2 (en) * 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7108778B2 (en) * 2003-07-25 2006-09-19 Dexcom, Inc. Electrochemical sensors including electrode systems with increased oxygen generation
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US8676287B2 (en) 2003-08-01 2014-03-18 Dexcom, Inc. System and methods for processing analyte sensor data
US8369919B2 (en) * 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US7925321B2 (en) * 2003-08-01 2011-04-12 Dexcom, Inc. System and methods for processing analyte sensor data
US8060173B2 (en) 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US9135402B2 (en) 2007-12-17 2015-09-15 Dexcom, Inc. Systems and methods for processing sensor data
US8886273B2 (en) 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US8233959B2 (en) * 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
USD914881S1 (en) 2003-11-05 2021-03-30 Abbott Diabetes Care Inc. Analyte sensor electronic mount
CA2544726C (en) 2003-11-07 2018-06-26 University Of Connecticut Artificial tissue systems and uses thereof
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8532730B2 (en) 2006-10-04 2013-09-10 Dexcom, Inc. Analyte sensor
DE602004029092D1 (de) * 2003-12-05 2010-10-21 Dexcom Inc Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7637868B2 (en) * 2004-01-12 2009-12-29 Dexcom, Inc. Composite material for implantable device
US20050182451A1 (en) * 2004-01-12 2005-08-18 Adam Griffin Implantable device with improved radio frequency capabilities
US8165651B2 (en) * 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
US7364592B2 (en) * 2004-02-12 2008-04-29 Dexcom, Inc. Biointerface membrane with macro-and micro-architecture
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US20050245799A1 (en) * 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US8277713B2 (en) * 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US20060010098A1 (en) 2004-06-04 2006-01-12 Goodnow Timothy T Diabetes care host-client architecture and data management system
US8886272B2 (en) 2004-07-13 2014-11-11 Dexcom, Inc. Analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
WO2006127694A2 (en) * 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US7946984B2 (en) * 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
US20060016700A1 (en) * 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
EP2329770B2 (de) 2004-07-13 2024-04-10 DexCom, Inc. Transkutaner Analytsensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US7731657B2 (en) * 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9636450B2 (en) 2007-02-19 2017-05-02 Udo Hoss Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
US20070027381A1 (en) * 2005-07-29 2007-02-01 Therasense, Inc. Inserter and methods of use
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
US20090105569A1 (en) * 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US8571624B2 (en) 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US7697967B2 (en) * 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8333714B2 (en) * 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
WO2006102412A2 (en) 2005-03-21 2006-09-28 Abbott Diabetes Care, Inc. Method and system for providing integrated medication infusion and analyte monitoring system
US8744546B2 (en) * 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US20060249381A1 (en) * 2005-05-05 2006-11-09 Petisce James R Cellulosic-based resistance domain for an analyte sensor
US8060174B2 (en) 2005-04-15 2011-11-15 Dexcom, Inc. Analyte sensing biointerface
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US7768408B2 (en) 2005-05-17 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing data management in data monitoring system
US7620437B2 (en) 2005-06-03 2009-11-17 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
GB0515477D0 (en) * 2005-07-28 2005-08-31 Smith & Nephew Composition
US20080314395A1 (en) 2005-08-31 2008-12-25 Theuniversity Of Virginia Patent Foundation Accuracy of Continuous Glucose Sensors
US7756561B2 (en) 2005-09-30 2010-07-13 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US8880138B2 (en) * 2005-09-30 2014-11-04 Abbott Diabetes Care Inc. Device for channeling fluid and methods of use
US7583190B2 (en) * 2005-10-31 2009-09-01 Abbott Diabetes Care Inc. Method and apparatus for providing data communication in data monitoring and management systems
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US8160670B2 (en) 2005-12-28 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring: stabilizer for subcutaneous glucose sensor with incorporated antiglycolytic agent
US8515518B2 (en) 2005-12-28 2013-08-20 Abbott Diabetes Care Inc. Analyte monitoring
EP1968432A4 (de) * 2005-12-28 2009-10-21 Abbott Diabetes Care Inc Einführung eines medizinischen gerätes
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8353881B2 (en) * 2005-12-28 2013-01-15 Abbott Diabetes Care Inc. Infusion sets for the delivery of a therapeutic substance to a patient
US7736310B2 (en) 2006-01-30 2010-06-15 Abbott Diabetes Care Inc. On-body medical device securement
US8344966B2 (en) * 2006-01-31 2013-01-01 Abbott Diabetes Care Inc. Method and system for providing a fault tolerant display unit in an electronic device
EP2407095A1 (de) 2006-02-22 2012-01-18 DexCom, Inc. Analytsensor
US7826879B2 (en) * 2006-02-28 2010-11-02 Abbott Diabetes Care Inc. Analyte sensors and methods of use
US7981034B2 (en) 2006-02-28 2011-07-19 Abbott Diabetes Care Inc. Smart messages and alerts for an infusion delivery and management system
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
EP4218548A1 (de) 2006-03-09 2023-08-02 Dexcom, Inc. Systeme und verfahren zur aufbereitung von analytensensordaten
US7653425B2 (en) 2006-08-09 2010-01-26 Abbott Diabetes Care Inc. Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US7630748B2 (en) 2006-10-25 2009-12-08 Abbott Diabetes Care Inc. Method and system for providing analyte monitoring
US8219173B2 (en) 2008-09-30 2012-07-10 Abbott Diabetes Care Inc. Optimizing analyte sensor calibration
US7618369B2 (en) 2006-10-02 2009-11-17 Abbott Diabetes Care Inc. Method and system for dynamically updating calibration parameters for an analyte sensor
US8346335B2 (en) 2008-03-28 2013-01-01 Abbott Diabetes Care Inc. Analyte sensor calibration management
US7801582B2 (en) 2006-03-31 2010-09-21 Abbott Diabetes Care Inc. Analyte monitoring and management system and methods therefor
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US9392969B2 (en) 2008-08-31 2016-07-19 Abbott Diabetes Care Inc. Closed loop control and signal attenuation detection
US8224415B2 (en) 2009-01-29 2012-07-17 Abbott Diabetes Care Inc. Method and device for providing offset model based calibration for analyte sensor
US8374668B1 (en) 2007-10-23 2013-02-12 Abbott Diabetes Care Inc. Analyte sensor with lag compensation
US8140312B2 (en) 2007-05-14 2012-03-20 Abbott Diabetes Care Inc. Method and system for determining analyte levels
US9675290B2 (en) 2012-10-30 2017-06-13 Abbott Diabetes Care Inc. Sensitivity calibration of in vivo sensors used to measure analyte concentration
US8473022B2 (en) 2008-01-31 2013-06-25 Abbott Diabetes Care Inc. Analyte sensor with time lag compensation
WO2007143225A2 (en) * 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
US20080004601A1 (en) * 2006-06-28 2008-01-03 Abbott Diabetes Care, Inc. Analyte Monitoring and Therapy Management System and Methods Therefor
US20090171269A1 (en) * 2006-06-29 2009-07-02 Abbott Diabetes Care, Inc. Infusion Device and Methods Therefor
US9119582B2 (en) 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
US20090105571A1 (en) * 2006-06-30 2009-04-23 Abbott Diabetes Care, Inc. Method and System for Providing Data Communication in Data Management Systems
US8206296B2 (en) 2006-08-07 2012-06-26 Abbott Diabetes Care Inc. Method and system for providing integrated analyte monitoring and infusion system therapy management
US8932216B2 (en) 2006-08-07 2015-01-13 Abbott Diabetes Care Inc. Method and system for providing data management in integrated analyte monitoring and infusion system
US7831287B2 (en) * 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP2106238A4 (de) 2006-10-26 2011-03-09 Abbott Diabetes Care Inc Verfahren, system und computerprogrammprodukt zur echtzeit-erkennung eines empfindlichkeitsabfalls in analytsensoren
US8579853B2 (en) 2006-10-31 2013-11-12 Abbott Diabetes Care Inc. Infusion devices and methods
US8121857B2 (en) 2007-02-15 2012-02-21 Abbott Diabetes Care Inc. Device and method for automatic data acquisition and/or detection
US20080199894A1 (en) * 2007-02-15 2008-08-21 Abbott Diabetes Care, Inc. Device and method for automatic data acquisition and/or detection
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
CA2681412A1 (en) 2007-03-26 2008-10-02 Dexcom, Inc. Analyte sensor
EP2146625B1 (de) 2007-04-14 2019-08-14 Abbott Diabetes Care Inc. Verfahren und gerät zur bereitstellung von datenverarbeitung und kontrolle in einem medizinischen kommunikationssystem
ES2817503T3 (es) * 2007-04-14 2021-04-07 Abbott Diabetes Care Inc Procedimiento y aparato para proporcionar el procesamiento y control de datos en un sistema de comunicación médica
CA2683721C (en) 2007-04-14 2017-05-23 Abbott Diabetes Care Inc. Method and apparatus for providing dynamic multi-stage signal amplification in a medical device
CA2683953C (en) 2007-04-14 2016-08-02 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
CA2683959C (en) * 2007-04-14 2017-08-29 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
WO2008128210A1 (en) 2007-04-14 2008-10-23 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in medical communication system
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US7996158B2 (en) 2007-05-14 2011-08-09 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8103471B2 (en) 2007-05-14 2012-01-24 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8560038B2 (en) 2007-05-14 2013-10-15 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US10002233B2 (en) * 2007-05-14 2018-06-19 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8444560B2 (en) 2007-05-14 2013-05-21 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8239166B2 (en) 2007-05-14 2012-08-07 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8260558B2 (en) 2007-05-14 2012-09-04 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8600681B2 (en) 2007-05-14 2013-12-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US9125548B2 (en) * 2007-05-14 2015-09-08 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
WO2008150917A1 (en) 2007-05-31 2008-12-11 Abbott Diabetes Care, Inc. Insertion devices and methods
WO2008154312A1 (en) 2007-06-08 2008-12-18 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US8133553B2 (en) * 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
JP5680960B2 (ja) 2007-06-21 2015-03-04 アボット ダイアベティス ケア インコーポレイテッドAbbott Diabetes Care Inc. 健康管理装置および方法
US8617069B2 (en) 2007-06-21 2013-12-31 Abbott Diabetes Care Inc. Health monitor
WO2008157819A1 (en) * 2007-06-21 2008-12-24 Abbott Diabetes Care, Inc. Health management devices and methods
US8641618B2 (en) * 2007-06-27 2014-02-04 Abbott Diabetes Care Inc. Method and structure for securing a monitoring device element
US8085151B2 (en) * 2007-06-28 2011-12-27 Abbott Diabetes Care Inc. Signal converting cradle for medical condition monitoring and management system
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
US8834366B2 (en) 2007-07-31 2014-09-16 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor calibration
US7768386B2 (en) * 2007-07-31 2010-08-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US9452258B2 (en) 2007-10-09 2016-09-27 Dexcom, Inc. Integrated insulin delivery system with continuous glucose sensor
US20110230973A1 (en) * 2007-10-10 2011-09-22 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US8608049B2 (en) * 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
DE102007051059B4 (de) * 2007-10-18 2014-04-03 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Bioverbundmaterial für die kontrollierte Freisetzung von Wirkstoffen
US8409093B2 (en) 2007-10-23 2013-04-02 Abbott Diabetes Care Inc. Assessing measures of glycemic variability
US8377031B2 (en) 2007-10-23 2013-02-19 Abbott Diabetes Care Inc. Closed loop control system with safety parameters and methods
US8216138B1 (en) 2007-10-23 2012-07-10 Abbott Diabetes Care Inc. Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration
US8417312B2 (en) 2007-10-25 2013-04-09 Dexcom, Inc. Systems and methods for processing sensor data
CA2702799A1 (en) 2007-10-25 2009-04-30 Dexcom, Inc. Systems and methods for processing sensor data
US20090112315A1 (en) * 2007-10-29 2009-04-30 Zimmer, Inc. Medical implants and methods for delivering biologically active agents
US8290559B2 (en) 2007-12-17 2012-10-16 Dexcom, Inc. Systems and methods for processing sensor data
US20090164190A1 (en) * 2007-12-19 2009-06-25 Abbott Diabetes Care, Inc. Physiological condition simulation device and method
US20090164239A1 (en) * 2007-12-19 2009-06-25 Abbott Diabetes Care, Inc. Dynamic Display Of Glucose Information
US20090187256A1 (en) * 2008-01-21 2009-07-23 Zimmer, Inc. Method for forming an integral porous region in a cast implant
JP5232484B2 (ja) * 2008-01-31 2013-07-10 日本特殊陶業株式会社 生体インプラント
US20090198286A1 (en) * 2008-02-05 2009-08-06 Zimmer, Inc. Bone fracture fixation system
US20090299156A1 (en) * 2008-02-20 2009-12-03 Dexcom, Inc. Continuous medicament sensor system for in vivo use
WO2009105709A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
CN102047101A (zh) 2008-03-28 2011-05-04 德克斯康公司 用于连续的分析物传感器的聚合物膜
JP5328203B2 (ja) 2008-03-31 2013-10-30 ユニ・チャーム株式会社 使い捨て吸収性着用物品
US20090259118A1 (en) * 2008-03-31 2009-10-15 Abbott Diabetes Care Inc. Shallow Implantable Analyte Sensor with Rapid Physiological Response
US8252229B2 (en) * 2008-04-10 2012-08-28 Abbott Diabetes Care Inc. Method and system for sterilizing an analyte sensor
US20090300616A1 (en) * 2008-05-30 2009-12-03 Abbott Diabetes Care, Inc. Automated task execution for an analyte monitoring system
US8591410B2 (en) 2008-05-30 2013-11-26 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US7826382B2 (en) 2008-05-30 2010-11-02 Abbott Diabetes Care Inc. Close proximity communication device and methods
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
WO2010009172A1 (en) 2008-07-14 2010-01-21 Abbott Diabetes Care Inc. Closed loop control system interface and methods
EP2149957B1 (de) * 2008-07-30 2017-06-14 Harman Becker Automotive Systems GmbH Stromverteilung nach Priorität
US8622988B2 (en) 2008-08-31 2014-01-07 Abbott Diabetes Care Inc. Variable rate closed loop control and methods
US20100057040A1 (en) 2008-08-31 2010-03-04 Abbott Diabetes Care, Inc. Robust Closed Loop Control And Methods
US9943644B2 (en) * 2008-08-31 2018-04-17 Abbott Diabetes Care Inc. Closed loop control with reference measurement and methods thereof
US8734422B2 (en) 2008-08-31 2014-05-27 Abbott Diabetes Care Inc. Closed loop control with improved alarm functions
EP2326944B1 (de) 2008-09-19 2020-08-19 Dexcom, Inc. Partikelhaltige membran und partikelelektrode für analytsensoren
US20100082364A1 (en) * 2008-09-30 2010-04-01 Abbott Diabetes Care, Inc. Medical Information Management
US8986208B2 (en) 2008-09-30 2015-03-24 Abbott Diabetes Care Inc. Analyte sensor sensitivity attenuation mitigation
US9326707B2 (en) 2008-11-10 2016-05-03 Abbott Diabetes Care Inc. Alarm characterization for analyte monitoring devices and systems
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US8560082B2 (en) 2009-01-30 2013-10-15 Abbott Diabetes Care Inc. Computerized determination of insulin pump therapy parameters using real time and retrospective data processing
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US20100247775A1 (en) * 2009-03-31 2010-09-30 Abbott Diabetes Care Inc. Precise Fluid Dispensing Method and Device
US8497777B2 (en) 2009-04-15 2013-07-30 Abbott Diabetes Care Inc. Analyte monitoring system having an alert
WO2010121229A1 (en) 2009-04-16 2010-10-21 Abbott Diabetes Care Inc. Analyte sensor calibration management
US20100274515A1 (en) * 2009-04-28 2010-10-28 Abbott Diabetes Care Inc. Dynamic Analyte Sensor Calibration Based On Sensor Stability Profile
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
WO2010129375A1 (en) 2009-04-28 2010-11-11 Abbott Diabetes Care Inc. Closed loop blood glucose control algorithm analysis
EP2424426B1 (de) 2009-04-29 2020-01-08 Abbott Diabetes Care, Inc. Verfahren und system zur datenübertragung in einem system für kontinuierliche glucoseüberwachung und glucosemanagement
US8483967B2 (en) 2009-04-29 2013-07-09 Abbott Diabetes Care Inc. Method and system for providing real time analyte sensor calibration with retrospective backfill
CA2716502C (en) 2009-05-15 2015-06-16 Interface Biologics, Inc. Antithrombogenic hollow fiber membranes and filters
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
US8613892B2 (en) 2009-06-30 2013-12-24 Abbott Diabetes Care Inc. Analyte meter with a moveable head and methods of using the same
DK3689237T3 (da) 2009-07-23 2021-08-16 Abbott Diabetes Care Inc Fremgangsmåde til fremstilling og system til kontinuerlig analytmåling
EP3936032A1 (de) 2009-07-23 2022-01-12 Abbott Diabetes Care, Inc. Echtzeitverwaltung von daten im zusammenhang mit der physiologischen kontrolle des blutzuckerspiegels
US9868974B2 (en) 2009-07-27 2018-01-16 SureSensors Ltd. Sensor devices
WO2011014851A1 (en) 2009-07-31 2011-02-03 Abbott Diabetes Care Inc. Method and apparatus for providing analyte monitoring system calibration accuracy
EP3923295A1 (de) 2009-08-31 2021-12-15 Abbott Diabetes Care, Inc. Medizinische vorrichtungen und verfahren
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
ES2912584T3 (es) 2009-08-31 2022-05-26 Abbott Diabetes Care Inc Un sistema y procedimiento de monitorización de glucosa
WO2011041469A1 (en) 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
WO2011041531A1 (en) 2009-09-30 2011-04-07 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
WO2011053881A1 (en) 2009-10-30 2011-05-05 Abbott Diabetes Care Inc. Method and apparatus for detecting false hypoglycemic conditions
CN102711855B (zh) 2009-11-25 2015-12-02 矽瑞奥科技公司 多孔生物相容性材料的颗粒
US20110184258A1 (en) * 2010-01-28 2011-07-28 Abbott Diabetes Care Inc. Balloon Catheter Analyte Measurement Sensors and Methods for Using the Same
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
WO2011112753A1 (en) 2010-03-10 2011-09-15 Abbott Diabetes Care Inc. Systems, devices and methods for managing glucose levels
ES2881798T3 (es) 2010-03-24 2021-11-30 Abbott Diabetes Care Inc Insertadores de dispositivos médicos y procedimientos de inserción y uso de dispositivos médicos
CN103037911B (zh) 2010-04-08 2015-07-15 矽瑞奥科技公司 具有微孔表面层的植入式医学装置及降低针对所述装置的异物反应的方法
FR2960783B1 (fr) * 2010-06-04 2012-07-27 Ass Pour Les Transferts De Technologies Du Mans Membrane fonctionnalisee pour chambre d'encapsulation de cellules produisant au moins une substance d'interet therapeutique et organe bioartificiel comprenant une telle membrane
US8635046B2 (en) 2010-06-23 2014-01-21 Abbott Diabetes Care Inc. Method and system for evaluating analyte sensor response characteristics
US10092229B2 (en) 2010-06-29 2018-10-09 Abbott Diabetes Care Inc. Calibration of analyte measurement system
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US9475709B2 (en) 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
US11213226B2 (en) 2010-10-07 2022-01-04 Abbott Diabetes Care Inc. Analyte monitoring devices and methods
US20140114436A1 (en) * 2011-02-17 2014-04-24 Patrick A. Tresco Medical devices and methods for improving the biocompatibility of medical devices
CN103619255B (zh) 2011-02-28 2016-11-02 雅培糖尿病护理公司 与分析物监测装置关联的装置、系统和方法以及结合了它们的装置
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US8844007B2 (en) 2011-04-08 2014-09-23 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
DK3575796T3 (da) 2011-04-15 2021-01-18 Dexcom Inc Avanceret analytsensorkalibrering og fejldetektion
JP6321540B2 (ja) 2011-07-26 2018-05-09 グリセンス インコーポレイテッド 気密密閉された筐体を備える埋め込み型分析物センサおよび該センサを製造する方法
EP3092949B1 (de) 2011-09-23 2020-12-09 Dexcom, Inc. Systeme und verfahren zur verarbeitung und übertragung von sensordaten
WO2013066873A1 (en) 2011-10-31 2013-05-10 Abbott Diabetes Care Inc. Electronic devices having integrated reset systems and methods thereof
WO2013066849A1 (en) 2011-10-31 2013-05-10 Abbott Diabetes Care Inc. Model based variable risk false glucose threshold alarm prevention mechanism
US9980669B2 (en) 2011-11-07 2018-05-29 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US8710993B2 (en) 2011-11-23 2014-04-29 Abbott Diabetes Care Inc. Mitigating single point failure of devices in an analyte monitoring system and methods thereof
US9317656B2 (en) 2011-11-23 2016-04-19 Abbott Diabetes Care Inc. Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof
WO2013078426A2 (en) 2011-11-25 2013-05-30 Abbott Diabetes Care Inc. Analyte monitoring system and methods of use
FI3300658T3 (fi) 2011-12-11 2024-03-01 Abbott Diabetes Care Inc Analyyttianturimenetelmiä
US9446031B2 (en) 2012-01-18 2016-09-20 National University Of Singapore Compositions and methods for neovascularization
US9615779B2 (en) 2012-04-04 2017-04-11 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
US9610546B2 (en) 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US9834809B2 (en) 2014-02-28 2017-12-05 Lockheed Martin Corporation Syringe for obtaining nano-sized materials for selective assays and related methods of use
US10418143B2 (en) 2015-08-05 2019-09-17 Lockheed Martin Corporation Perforatable sheets of graphene-based material
US10376845B2 (en) 2016-04-14 2019-08-13 Lockheed Martin Corporation Membranes with tunable selectivity
US9744617B2 (en) 2014-01-31 2017-08-29 Lockheed Martin Corporation Methods for perforating multi-layer graphene through ion bombardment
US10653824B2 (en) 2012-05-25 2020-05-19 Lockheed Martin Corporation Two-dimensional materials and uses thereof
US20130321425A1 (en) 2012-06-05 2013-12-05 Dexcom, Inc. Reporting modules
US10881339B2 (en) 2012-06-29 2021-01-05 Dexcom, Inc. Use of sensor redundancy to detect sensor failures
US10598627B2 (en) 2012-06-29 2020-03-24 Dexcom, Inc. Devices, systems, and methods to compensate for effects of temperature on implantable sensors
US20140012117A1 (en) 2012-07-09 2014-01-09 Dexcom, Inc. Systems and methods for leveraging smartphone features in continuous glucose monitoring
US10561353B2 (en) * 2016-06-01 2020-02-18 Glysens Incorporated Biocompatible implantable sensor apparatus and methods
US10660550B2 (en) 2015-12-29 2020-05-26 Glysens Incorporated Implantable sensor apparatus and methods
EP3395252A1 (de) 2012-08-30 2018-10-31 Abbott Diabetes Care, Inc. Ausfallerkennung bei kontinuierlichen analytüberwachungsdaten bei datenabweichungen
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US9907492B2 (en) 2012-09-26 2018-03-06 Abbott Diabetes Care Inc. Method and apparatus for improving lag correction during in vivo measurement of analyte concentration with analyte concentration variability and range data
US9788765B2 (en) 2012-09-28 2017-10-17 Dexcom, Inc. Zwitterion surface modifications for continuous sensors
US20140129151A1 (en) 2012-11-07 2014-05-08 Dexcom, Inc. Systems and methods for managing glycemic variability
EP2938249B1 (de) * 2012-12-28 2019-10-23 Senseonics, Incorporated Analytdurchlässige membransysteme für oxidative und optische stabilität
US11109779B2 (en) 2012-12-28 2021-09-07 Senseonics, Incorporated Chemical modification of analyte permeable membrane for enhanced oxidative stability
US9585563B2 (en) 2012-12-31 2017-03-07 Dexcom, Inc. Remote monitoring of analyte measurements
US9730620B2 (en) 2012-12-31 2017-08-15 Dexcom, Inc. Remote monitoring of analyte measurements
WO2014164621A1 (en) 2013-03-12 2014-10-09 Lockheed Martin Corporation Method for forming filter with uniform aperture size
US10130288B2 (en) 2013-03-14 2018-11-20 Cell and Molecular Tissue Engineering, LLC Coated sensors, and corresponding systems and methods
US9445445B2 (en) 2013-03-14 2016-09-13 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
US10405961B2 (en) 2013-03-14 2019-09-10 Cell and Molecular Tissue Engineering, LLC Coated surgical mesh, and corresponding systems and methods
US10335075B2 (en) 2013-03-14 2019-07-02 Dexcom, Inc. Advanced calibration for analyte sensors
EP4220654A1 (de) 2013-03-14 2023-08-02 Dexcom, Inc. Systeme und verfahren zur verarbeitung und übertragung von sensordaten
US9474475B1 (en) 2013-03-15 2016-10-25 Abbott Diabetes Care Inc. Multi-rate analyte sensor data collection with sample rate configurable signal processing
WO2014152034A1 (en) 2013-03-15 2014-09-25 Abbott Diabetes Care Inc. Sensor fault detection using analyte sensor data pattern comparison
US10433773B1 (en) 2013-03-15 2019-10-08 Abbott Diabetes Care Inc. Noise rejection methods and apparatus for sparsely sampled analyte sensor data
US9572918B2 (en) 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
EP3079732B1 (de) 2013-12-10 2019-04-10 Nova Plasma Ltd Behälter, vorrichtung und verfahren zur handhabung eines implantats
CA2933166C (en) 2013-12-31 2020-10-27 Abbott Diabetes Care Inc. Self-powered analyte sensor and devices using the same
CN105940479A (zh) 2014-01-31 2016-09-14 洛克希德马丁公司 使用宽离子场穿孔二维材料
EP3099645A4 (de) 2014-01-31 2017-09-27 Lockheed Martin Corporation Verfahren zur formung von verbundstrukturen mit einem zweidimensionalen material unter verwendung einer porösen, nichtbeschädigenden trägerschicht
CN106232205A (zh) 2014-03-12 2016-12-14 洛克希德马丁公司 由有孔石墨烯形成的分离膜
EP4151150A1 (de) 2014-03-30 2023-03-22 Abbott Diabetes Care, Inc. Verfahren und gerät zum bestimmen von mahlzeitenbeginn und peak-ereignissen in analytischen überwachungssystemen
FI3128902T3 (fi) 2014-04-10 2023-11-16 Dexcom Inc Anturi analyytin jatkuvaan seurantaan
AU2015311978A1 (en) 2014-09-02 2017-05-11 Lockheed Martin Corporation Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same
CN107614023A (zh) 2015-05-11 2018-01-19 诺瓦普拉斯玛有限公司 用于处理植入体的装置和方法
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
WO2016183493A1 (en) 2015-05-14 2016-11-17 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
US20180125780A1 (en) 2015-05-15 2018-05-10 The Methodist Hospital System Implantable nanochannel delivery devices
WO2017011346A1 (en) 2015-07-10 2017-01-19 Abbott Diabetes Care Inc. System, device and method of dynamic glucose profile response to physiological parameters
MX2018001559A (es) 2015-08-06 2018-09-27 Lockheed Corp Modificacion de nanoparticula y perforacion de grafeno.
ES2911676T3 (es) 2015-10-21 2022-05-20 Dexcom Inc Sensores de analito transcutáneos, aplicadores para los mismos y métodos asociados
EP3397140A4 (de) 2015-12-28 2019-08-21 Dexcom, Inc. Systeme und verfahren zur fern- und host-überwachung von kommunikationen
WO2017117472A1 (en) 2015-12-30 2017-07-06 Dexcom, Inc. Biointerface layer for analyte sensors
CA3133253A1 (en) 2016-03-31 2017-10-05 Dexcom, Inc. Systems and methods for display device and sensor electronics unit communication
EP3442786A4 (de) 2016-04-14 2020-03-18 Lockheed Martin Corporation Zweidimensionale membranstrukturen mit strömungskanälen
SG11201808961QA (en) 2016-04-14 2018-11-29 Lockheed Corp Methods for in situ monitoring and control of defect formation or healing
CA3020686A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Method for treating graphene sheets for large-scale transfer using free-float method
JP2019521055A (ja) 2016-04-14 2019-07-25 ロッキード・マーチン・コーポレーション グラフェン欠陥の選択的界面緩和
WO2017180134A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Methods for in vivo and in vitro use of graphene and other two-dimensional materials
US20190142317A1 (en) * 2016-05-10 2019-05-16 Interface Biologics, Inc. Implantable glucose sensors having a biostable surface
US10638962B2 (en) * 2016-06-29 2020-05-05 Glysens Incorporated Bio-adaptable implantable sensor apparatus and methods
CN110167995B (zh) 2016-10-18 2022-07-01 界面生物公司 具有表面改性大分子的塑化pvc混合物和由其制成的制品
CN110461217B (zh) 2017-01-23 2022-09-16 雅培糖尿病护理公司 用于分析物传感器插入的系统、装置和方法
US11596330B2 (en) 2017-03-21 2023-03-07 Abbott Diabetes Care Inc. Methods, devices and system for providing diabetic condition diagnosis and therapy
KR20200067124A (ko) 2017-06-23 2020-06-11 덱스콤, 인크. 경피성 분석 센서, 이를 위한 어플리케이터 및 관련 방법
US10638979B2 (en) 2017-07-10 2020-05-05 Glysens Incorporated Analyte sensor data evaluation and error reduction apparatus and methods
US11495438B2 (en) 2017-08-16 2022-11-08 Nova Plasma Ltd. Plasma treating an implant
CA3116829A1 (en) * 2017-10-17 2019-04-25 The Methodist Hospital System Delivery devices
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US20190120785A1 (en) 2017-10-24 2019-04-25 Dexcom, Inc. Pre-connected analyte sensors
US11278668B2 (en) 2017-12-22 2022-03-22 Glysens Incorporated Analyte sensor and medicant delivery data evaluation and error reduction apparatus and methods
US11255839B2 (en) 2018-01-04 2022-02-22 Glysens Incorporated Apparatus and methods for analyte sensor mismatch correction
CN112040839A (zh) * 2018-02-09 2020-12-04 W.L.戈尔及同仁股份有限公司 可植入进入室及相关联的使用方法
CN111801425B (zh) 2018-02-28 2024-02-23 豪夫迈·罗氏有限公司 用于连续分析物测量的生物相容性涂层
WO2020092897A1 (en) 2018-11-02 2020-05-07 Senseonics, Incorporated Drug eluting matrix on analyte indicator
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
CN113750290A (zh) * 2020-06-03 2021-12-07 深圳先进技术研究院 聚醚醚酮复合植入物及其制备方法和应用
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
CA3210177A1 (en) 2021-03-19 2022-09-22 Dexcom, Inc. Drug releasing membrane for analyte sensor
AU2022249389A1 (en) 2021-04-02 2023-11-02 Dexcom, Inc. Personalized modeling of blood glucose concentration impacted by individualized sensor characteristics and individualized physiological characteristics
WO2023043908A1 (en) 2021-09-15 2023-03-23 Dexcom, Inc. Bioactive releasing membrane for analyte sensor
CN114748208B (zh) * 2022-04-15 2024-01-12 柔脉医疗(深圳)有限公司 一种可原位检测多种化学、生物成分的组织工程支架
US20240090802A1 (en) 2022-09-02 2024-03-21 Dexcom, Inc. Continuous analyte sensor devices and methods

Family Cites Families (397)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19852258A1 (de) 1998-11-11 2000-05-18 Agfa Gevaert Ag Strahlungsempfindliches Aufzeichnungsmaterial zur Herstellung von Wasserlos-Offsetdruckplatten
US3016448A (en) * 1959-09-04 1962-01-09 Western Electric Co Automatic wiring machine
USRE31916E (en) * 1970-11-10 1985-06-18 Becton Dickinson & Company Electrochemical detection cell
GB1412983A (en) 1971-11-30 1975-11-05 Debell & Richardson Method of producing porous plastic materials
US3943918A (en) * 1971-12-02 1976-03-16 Tel-Pac, Inc. Disposable physiological telemetric device
US3957651A (en) * 1971-12-16 1976-05-18 Chemical Systems Incorporated Microporous polyester membranes and polymer assisted phase inversion process for their manufacture
US3775182A (en) 1972-02-25 1973-11-27 Du Pont Tubular electrochemical cell with coiled electrodes and compressed central spindle
GB1442303A (en) 1972-09-08 1976-07-14 Radiometer As Cell for electro-chemical analysis
CS164231B2 (de) 1972-09-28 1975-11-07
US3929971A (en) 1973-03-30 1975-12-30 Research Corp Porous biomaterials and method of making same
US3898984A (en) * 1974-02-04 1975-08-12 Us Navy Ambulatory patient monitoring system
US3966580A (en) 1974-09-16 1976-06-29 The University Of Utah Novel protein-immobilizing hydrophobic polymeric membrane, process for producing same and apparatus employing same
US3979274A (en) 1975-09-24 1976-09-07 The Yellow Springs Instrument Company, Inc. Membrane for enzyme electrodes
CH591237A5 (de) 1975-11-06 1977-09-15 Bbc Brown Boveri & Cie
US4040908A (en) 1976-03-12 1977-08-09 Children's Hospital Medical Center Polarographic analysis of cholesterol and other macromolecular substances
US4024312A (en) 1976-06-23 1977-05-17 Johnson & Johnson Pressure-sensitive adhesive tape having extensible and elastic backing composed of a block copolymer
JPS5921500B2 (ja) 1978-01-28 1984-05-21 東洋紡績株式会社 酸素電極用酵素膜
US4172770A (en) 1978-03-27 1979-10-30 Technicon Instruments Corporation Flow-through electrochemical system analytical method
US4259540A (en) 1978-05-30 1981-03-31 Bell Telephone Laboratories, Incorporated Filled cables
US4215703A (en) 1978-08-29 1980-08-05 Willson James K V Variable stiffness guide wire
US4255500A (en) 1979-03-29 1981-03-10 General Electric Company Vibration resistant electrochemical cell having deformed casing and method of making same
US4253469A (en) * 1979-04-20 1981-03-03 The Narda Microwave Corporation Implantable temperature probe
DE2932761A1 (de) 1979-08-13 1981-02-26 Akzo Gmbh Polycarbonat-polyaether-copolymermembran
JPS5627643A (en) 1979-08-14 1981-03-18 Toshiba Corp Electrochemical measuring device
US4260725A (en) * 1979-12-10 1981-04-07 Bausch & Lomb Incorporated Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains
US4403984A (en) * 1979-12-28 1983-09-13 Biotek, Inc. System for demand-based adminstration of insulin
US4861830A (en) 1980-02-29 1989-08-29 Th. Goldschmidt Ag Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming
SE419903B (sv) 1980-03-05 1981-08-31 Enfors Sven Olof Enzymelektrod
DE3173564D1 (en) 1980-09-02 1986-03-06 Medtronic Inc Subcutaneously implantable lead with drug dispenser means
IE51643B1 (en) 1980-10-15 1987-01-21 Smith & Nephew Ass Coated articles and materials suitable for coating
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4436094A (en) 1981-03-09 1984-03-13 Evreka, Inc. Monitor for continuous in vivo measurement of glucose concentration
US4442841A (en) * 1981-04-30 1984-04-17 Mitsubishi Rayon Company Limited Electrode for living bodies
US4431004A (en) 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4418148A (en) 1981-11-05 1983-11-29 Miles Laboratories, Inc. Multilayer enzyme electrode membrane
US4415666A (en) 1981-11-05 1983-11-15 Miles Laboratories, Inc. Enzyme electrode membrane
US4494950A (en) * 1982-01-19 1985-01-22 The Johns Hopkins University Plural module medication delivery system
EP0098592A3 (de) 1982-07-06 1985-08-21 Fujisawa Pharmaceutical Co., Ltd. Tragbare künstliche Bauchspeicheldrüse
DE3228551A1 (de) * 1982-07-30 1984-02-02 Siemens AG, 1000 Berlin und 8000 München Verfahren zur bestimmung der zuckerkonzentration
US4571292A (en) * 1982-08-12 1986-02-18 Case Western Reserve University Apparatus for electrochemical measurements
DE3379589D1 (en) 1982-10-25 1989-05-18 Hellgren Lars G I Enzyme composition for cleaning, the use thereof and preparation of the composition
US5059654A (en) 1983-02-14 1991-10-22 Cuno Inc. Affinity matrices of modified polysaccharide supports
US4506680A (en) 1983-03-17 1985-03-26 Medtronic, Inc. Drug dispensing body implantable lead
CA1226036A (en) 1983-05-05 1987-08-25 Irving J. Higgins Analytical equipment and sensor electrodes therefor
US4650547A (en) 1983-05-19 1987-03-17 The Regents Of The University Of California Method and membrane applicable to implantable sensor
US4484987A (en) 1983-05-19 1984-11-27 The Regents Of The University Of California Method and membrane applicable to implantable sensor
WO1985000463A1 (en) 1983-07-05 1985-01-31 Matsushita Electric Industrial Co., Ltd. Aluminum electrolytic capacitor and method of manufacture thereof
US4554927A (en) 1983-08-30 1985-11-26 Thermometrics Inc. Pressure and temperature sensor
GB2149918A (en) 1983-11-03 1985-06-19 John Anderson Sudden infant death syndrome monitor
US4753652A (en) 1984-05-04 1988-06-28 Children's Medical Center Corporation Biomaterial implants which resist calcification
US4883057A (en) 1984-05-09 1989-11-28 Research Foundation, The City University Of New York Cathodic electrochemical current arrangement with telemetric application
US5171689A (en) 1984-11-08 1992-12-15 Matsushita Electric Industrial Co., Ltd. Solid state bio-sensor
US4702732A (en) 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
US4963595A (en) 1985-01-04 1990-10-16 Thoratec Laboratories Corporation Polysiloxane-polylactone block copolymers
US5235003A (en) 1985-01-04 1993-08-10 Thoratec Laboratories Corporation Polysiloxane-polylactone block copolymers
US4577642A (en) 1985-02-27 1986-03-25 Medtronic, Inc. Drug dispensing body implantable lead employing molecular sieves and methods of fabrication
US4781798A (en) 1985-04-19 1988-11-01 The Regents Of The University Of California Transparent multi-oxygen sensor array and method of using same
US4671288A (en) 1985-06-13 1987-06-09 The Regents Of The University Of California Electrochemical cell sensor for continuous short-term use in tissues and blood
US4680268A (en) * 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
US4890620A (en) 1985-09-20 1990-01-02 The Regents Of The University Of California Two-dimensional diffusion glucose substrate sensing electrode
US4689309A (en) 1985-09-30 1987-08-25 Miles Laboratories, Inc. Test device, method of manufacturing same and method of determining a component in a sample
US4839296A (en) * 1985-10-18 1989-06-13 Chem-Elec, Inc. Blood plasma test method
US4776944A (en) 1986-03-20 1988-10-11 Jiri Janata Chemical selective sensors utilizing admittance modulated membranes
JPS62225513A (ja) 1986-03-26 1987-10-03 Shin Etsu Chem Co Ltd ブロツク・グラフト共重合体及びその製造法
US4994167A (en) 1986-04-15 1991-02-19 Markwell Medical Institute, Inc. Biological fluid measuring device
US4757022A (en) 1986-04-15 1988-07-12 Markwell Medical Institute, Inc. Biological fluid measuring device
US4703756A (en) 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US4731726A (en) * 1986-05-19 1988-03-15 Healthware Corporation Patient-operated glucose monitor and diabetes management system
GB8612861D0 (en) 1986-05-27 1986-07-02 Cambridge Life Sciences Immobilised enzyme biosensors
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US5002572A (en) 1986-09-11 1991-03-26 Picha George J Biological implant with textured surface
US5007929B1 (en) 1986-11-04 1994-08-30 Medical Products Dev Open-cell silicone-elastomer medical implant
AU617667B2 (en) 1986-11-04 1991-12-05 Allergan, Inc. Open-cell, silicone-elastomer medical implant and method for making
AT391063B (de) 1987-01-08 1990-08-10 Blum Gmbh Julius Verbindungsbeschlag zur befestigung der reling einer schublade
US4935345A (en) 1987-04-07 1990-06-19 Arizona Board Of Regents Implantable microelectronic biochemical sensor incorporating thin film thermopile
US4759828A (en) 1987-04-09 1988-07-26 Nova Biomedical Corporation Glucose electrode and method of determining glucose
US5540828A (en) 1987-06-08 1996-07-30 Yacynych; Alexander Method for making electrochemical sensors and biosensors having a polymer modified surface
US4810470A (en) 1987-06-19 1989-03-07 Miles Inc. Volume independent diagnostic device
JPH07122624B2 (ja) 1987-07-06 1995-12-25 ダイキン工業株式会社 バイオセンサ
US4805625A (en) * 1987-07-08 1989-02-21 Ad-Tech Medical Instrument Corporation Sphenoidal electrode and insertion method
FI77569C (fi) 1987-07-13 1989-04-10 Huhtamaeki Oy Anordning foer bestaemning av saorlaekningsfoermaogan i ett operationssaor eller en vaevnad.
US4974929A (en) 1987-09-22 1990-12-04 Baxter International, Inc. Fiber optical probe connector for physiologic measurement devices
GB8725936D0 (en) 1987-11-05 1987-12-09 Genetics Int Inc Sensing system
US4852573A (en) * 1987-12-04 1989-08-01 Kennedy Philip R Implantable neural electrode
US4849458A (en) 1988-06-17 1989-07-18 Matrix Medica, Inc. Segmented polyether polyurethane
EP0353328A1 (de) 1988-08-03 1990-02-07 Dräger Nederland B.V. Polarographische-amperometrische Drei-Elektroden-Messsonde
US5458631A (en) * 1989-01-06 1995-10-17 Xavier; Ravi Implantable catheter with electrical pulse nerve stimulators and drug delivery system
US5269891A (en) 1989-03-09 1993-12-14 Novo Nordisk A/S Method and apparatus for determination of a constituent in a fluid
JPH02298855A (ja) 1989-03-20 1990-12-11 Assoc Univ Inc 固定化酵素とレドックス重合体を用いた電気化学的バイオセンサー
US4986671A (en) 1989-04-12 1991-01-22 Luxtron Corporation Three-parameter optical fiber sensor and system
US4953552A (en) * 1989-04-21 1990-09-04 Demarzo Arthur P Blood glucose monitoring system
US4927407A (en) 1989-06-19 1990-05-22 Regents Of The University Of Minnesota Cardiac assist pump with steady rate supply of fluid lubricant
CH677149A5 (de) 1989-07-07 1991-04-15 Disetronic Ag
US5431160A (en) 1989-07-19 1995-07-11 University Of New Mexico Miniature implantable refillable glucose sensor and material therefor
US4986271A (en) * 1989-07-19 1991-01-22 The University Of New Mexico Vivo refillable glucose sensor
US5264104A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
US5190041A (en) 1989-08-11 1993-03-02 Palti Yoram Prof System for monitoring and controlling blood glucose
US5101814A (en) 1989-08-11 1992-04-07 Palti Yoram Prof System for monitoring and controlling blood glucose
US5050612A (en) * 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
JPH03133440A (ja) * 1989-10-18 1991-06-06 Nishitomo:Kk 婦人用体温計
US5067491A (en) 1989-12-08 1991-11-26 Becton, Dickinson And Company Barrier coating on blood contacting devices
US5985129A (en) 1989-12-14 1999-11-16 The Regents Of The University Of California Method for increasing the service life of an implantable sensor
US5265608A (en) * 1990-02-22 1993-11-30 Medtronic, Inc. Steroid eluting electrode for peripheral nerve stimulation
US5031618A (en) 1990-03-07 1991-07-16 Medtronic, Inc. Position-responsive neuro stimulator
US5316008A (en) * 1990-04-06 1994-05-31 Casio Computer Co., Ltd. Measurement of electrocardiographic wave and sphygmus
US5165407A (en) 1990-04-19 1992-11-24 The University Of Kansas Implantable glucose sensor
US5331555A (en) * 1990-05-11 1994-07-19 Sharp Kabushiki Kaisha Electronic apparatus
IT1248934B (it) 1990-06-01 1995-02-11 Fidia Spa Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle
US5282844A (en) * 1990-06-15 1994-02-01 Medtronic, Inc. High impedance, low polarization, low threshold miniature steriod eluting pacing lead electrodes
CA2090435C (en) 1990-08-28 2000-12-12 Peter J. Schmitt Self-supporting woven vascular graft
US5380536A (en) 1990-10-15 1995-01-10 The Board Of Regents, The University Of Texas System Biocompatible microcapsules
BR9106205A (pt) * 1990-10-31 1993-03-30 Baxter Int Dispositivo para implantacao em hospedeiro,processo de implantacao,dispositivo implantado,e recipiente de imunoisolamento
US5713888A (en) 1990-10-31 1998-02-03 Baxter International, Inc. Tissue implant systems
US5344454A (en) 1991-07-24 1994-09-06 Baxter International Inc. Closed porous chambers for implanting tissue in a host
US5733336A (en) 1990-10-31 1998-03-31 Baxter International, Inc. Ported tissue implant systems and methods of using same
US5314471A (en) 1991-07-24 1994-05-24 Baxter International Inc. Tissue inplant systems and methods for sustaining viable high cell densities within a host
US5348788A (en) 1991-01-30 1994-09-20 Interpore Orthopaedics, Inc. Mesh sheet with microscopic projections and holes
JPH04278450A (ja) 1991-03-04 1992-10-05 Adam Heller バイオセンサー及び分析物を分析する方法
US5593852A (en) 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
US5397848A (en) 1991-04-25 1995-03-14 Allergan, Inc. Enhancing the hydrophilicity of silicone polymers
US5271736A (en) 1991-05-13 1993-12-21 Applied Medical Research Collagen disruptive morphology for implants
JP3118015B2 (ja) 1991-05-17 2000-12-18 アークレイ株式会社 バイオセンサーおよびそれを用いた分離定量方法
FI88223C (fi) 1991-05-22 1993-04-13 Polar Electro Oy Telemetrisk saendarenhet
JP3084642B2 (ja) 1991-05-30 2000-09-04 株式会社ジェルテック 整姿用パッド並びにその製造方法
US5453278A (en) 1991-07-24 1995-09-26 Baxter International Inc. Laminated barriers for tissue implants
DE4130742A1 (de) 1991-09-16 1993-03-18 Inst Diabetestechnologie Gemei Verfahren und anordnung zur bestimmung der konzentration von inhaltsstoffen in koerperfluessigkeiten
ES2225819T3 (es) * 1991-09-20 2005-03-16 Amgen Inc. Factor neurotrofico de origen glial.
US5222980A (en) * 1991-09-27 1993-06-29 Medtronic, Inc. Implantable heart-assist device
US5322063A (en) 1991-10-04 1994-06-21 Eli Lilly And Company Hydrophilic polyurethane membranes for electrochemical glucose sensors
US5605162A (en) 1991-10-15 1997-02-25 Advanced Cardiovascular Systems, Inc. Method for using a variable stiffness guidewire
US5249576A (en) * 1991-10-24 1993-10-05 Boc Health Care, Inc. Universal pulse oximeter probe
US5866217A (en) 1991-11-04 1999-02-02 Possis Medical, Inc. Silicone composite vascular graft
US5310469A (en) 1991-12-31 1994-05-10 Abbott Laboratories Biosensor with a membrane containing biologically active material
EP0553372B1 (de) 1992-01-29 1996-11-13 Hewlett-Packard GmbH Verfahren und System zur Überwachung von Lebensfunktionen
WO1993014693A1 (en) * 1992-02-01 1993-08-05 The Victoria University Of Manchester Electrode
NL9200207A (nl) 1992-02-05 1993-09-01 Nedap Nv Implanteerbare biomedische sensorinrichting, in het bijzonder voor meting van de glucoseconcentratie.
US5284140A (en) 1992-02-11 1994-02-08 Eli Lilly And Company Acrylic copolymer membranes for biosensors
US5382514A (en) * 1992-03-31 1995-01-17 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services In vivo angiogenesis assay
US5589563A (en) 1992-04-24 1996-12-31 The Polymer Technology Group Surface-modifying endgroups for biomedical polymers
DE69320470T2 (de) 1992-04-24 1999-04-29 Polymer Technology Group Inc Copolymere, sowie daraus hergestellte nichtporöse halbdurchlässige membranen und ihre verwendung zum filtern von molekülen in einem vorgegebenen molekulargewichtbereich
GB9211402D0 (en) 1992-05-29 1992-07-15 Univ Manchester Sensor devices
US5330521A (en) 1992-06-29 1994-07-19 Cohen Donald M Low resistance implantable electrical leads
JP2541081B2 (ja) 1992-08-28 1996-10-09 日本電気株式会社 バイオセンサ及びバイオセンサの製造・使用方法
WO1994007593A1 (en) 1992-10-01 1994-04-14 Australian Membrane And Biotechnology Research Institute Improved sensor membranes
GB9221099D0 (en) 1992-10-07 1992-11-18 Ecossensors Ltd Improvements in and relating to gas permeable membranes for amperometric gas electrodes
US5387327A (en) 1992-10-19 1995-02-07 Duquesne University Of The Holy Ghost Implantable non-enzymatic electrochemical glucose sensor
US5399671A (en) * 1992-11-18 1995-03-21 Kluger; Ronald Specifically crosslinked hemoglobin with free functionality
ZA938555B (en) 1992-11-23 1994-08-02 Lilly Co Eli Technique to improve the performance of electrochemical sensors
US6256522B1 (en) 1992-11-23 2001-07-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Sensors for continuous monitoring of biochemicals and related method
US5285513A (en) 1992-11-30 1994-02-08 At&T Bell Laboratories Optical fiber cable provided with stabilized waterblocking material
US5299571A (en) * 1993-01-22 1994-04-05 Eli Lilly And Company Apparatus and method for implantation of sensors
DE4329898A1 (de) * 1993-09-04 1995-04-06 Marcus Dr Besson Kabelloses medizinisches Diagnose- und Überwachungsgerät
JPH08503715A (ja) * 1993-09-24 1996-04-23 バクスター、インターナショナル、インコーポレイテッド 埋め込み装置の血管化を促進するための方法
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
AU696167B2 (en) * 1993-10-29 1998-09-03 Trustees Of Boston University Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
KR970010981B1 (ko) 1993-11-04 1997-07-05 엘지전자 주식회사 알콜농도 측정용 바이오센서 및 바이오센서 제조방법과 바이오센서를 이용한 음주 측정기
US5545220A (en) 1993-11-04 1996-08-13 Lipomatrix Incorporated Implantable prosthesis with open cell textured surface and method for forming same
US5791344A (en) 1993-11-19 1998-08-11 Alfred E. Mann Foundation For Scientific Research Patient monitoring system
US5497772A (en) * 1993-11-19 1996-03-12 Alfred E. Mann Foundation For Scientific Research Glucose monitoring system
US5443080A (en) 1993-12-22 1995-08-22 Americate Transtech, Inc. Integrated system for biological fluid constituent analysis
US5437824A (en) 1993-12-23 1995-08-01 Moghan Medical Corp. Method of forming a molded silicone foam implant having open-celled interstices
US5549675A (en) 1994-01-11 1996-08-27 Baxter International, Inc. Method for implanting tissue in a host
DE4401400A1 (de) * 1994-01-19 1995-07-20 Ernst Prof Dr Pfeiffer Verfahren und Anordnung zur kontinuierlichen Überwachung der Konzentration eines Metaboliten
US5391250A (en) 1994-03-15 1995-02-21 Minimed Inc. Method of fabricating thin film sensors
US5390671A (en) * 1994-03-15 1995-02-21 Minimed Inc. Transcutaneous sensor insertion set
AUPM506894A0 (en) * 1994-04-14 1994-05-05 Memtec Limited Novel electrochemical cells
US5569186A (en) 1994-04-25 1996-10-29 Minimed Inc. Closed loop infusion pump system with removable glucose sensor
US5584876A (en) 1994-04-29 1996-12-17 W. L. Gore & Associates, Inc. Cell excluding sheath for vascular grafts
DE4415896A1 (de) * 1994-05-05 1995-11-09 Boehringer Mannheim Gmbh Analysesystem zur Überwachung der Konzentration eines Analyten im Blut eines Patienten
US5484404A (en) 1994-05-06 1996-01-16 Alfred E. Mann Foundation For Scientific Research Replaceable catheter system for physiological sensors, tissue stimulating electrodes and/or implantable fluid delivery systems
EP0685735B1 (de) 1994-06-03 2002-01-16 Metrohm Ag Vorrichtung für die Voltammetrie, Indikatorelektroden-Anordnung für eine solche Vorrichtung, insbesondere als Teil einer Bandkassette, und Reihenanalyse-Verfahren für die Voltammetrie
DE4422068A1 (de) * 1994-06-23 1996-01-04 Siemens Ag Elektrokatalytischer Glucosesensor
US5529066A (en) * 1994-06-27 1996-06-25 Cb-Carmel Biotechnology Ltd. Implantable capsule for enhancing cell electric signals
US5494562A (en) * 1994-06-27 1996-02-27 Ciba Corning Diagnostics Corp. Electrochemical sensors
US5480711A (en) * 1994-07-12 1996-01-02 Ruefer; Bruce G. Nano-porous PTFE biomaterial
US5513636A (en) * 1994-08-12 1996-05-07 Cb-Carmel Biotechnology Ltd. Implantable sensor chip
US5462051A (en) * 1994-08-31 1995-10-31 Colin Corporation Medical communication system
AT402452B (de) 1994-09-14 1997-05-26 Avl Verbrennungskraft Messtech Planarer sensor zum erfassen eines chemischen parameters einer probe
US5624537A (en) 1994-09-20 1997-04-29 The University Of British Columbia - University-Industry Liaison Office Biosensor and interface membrane
US5807406A (en) 1994-10-07 1998-09-15 Baxter International Inc. Porous microfabricated polymer membrane structures
CA2159052C (en) 1994-10-28 2007-03-06 Rainer Alex Injection device
IE72524B1 (en) * 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US5590651A (en) 1995-01-17 1997-01-07 Temple University - Of The Commonwealth System Of Higher Education Breathable liquid elimination analysis
US5837728A (en) 1995-01-27 1998-11-17 Molecular Design International 9-cis retinoic acid esters and amides and uses thereof
US5697366A (en) 1995-01-27 1997-12-16 Optical Sensors Incorporated In situ calibration system for sensors located in a physiologic line
US5586553A (en) 1995-02-16 1996-12-24 Minimed Inc. Transcutaneous sensor insertion set
US5568806A (en) 1995-02-16 1996-10-29 Minimed Inc. Transcutaneous sensor insertion set
US5882494A (en) 1995-03-27 1999-03-16 Minimed, Inc. Polyurethane/polyurea compositions containing silicone for biosensor membranes
US5620579A (en) 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
US5626561A (en) 1995-06-07 1997-05-06 Gore Hybrid Technologies, Inc. Implantable containment apparatus for a therapeutical device and method for loading and reloading the device therein
US5743262A (en) * 1995-06-07 1998-04-28 Masimo Corporation Blood glucose monitoring system
JPH10503964A (ja) 1995-06-07 1998-04-14 ゴア ハイブリッド テクノロジーズ,インコーポレイティド 治療用デバイスのための移植可能な閉じ込め装置並びにその中にそのデバイスを装填及び再装填する方法
US5656707A (en) 1995-06-16 1997-08-12 Regents Of The University Of Minnesota Highly cross-linked polymeric supports
US5995860A (en) * 1995-07-06 1999-11-30 Thomas Jefferson University Implantable sensor and system for measurement and control of blood constituent levels
US6001471A (en) 1995-08-11 1999-12-14 3M Innovative Properties Company Removable adhesive tape with controlled sequential release
US5628890A (en) 1995-09-27 1997-05-13 Medisense, Inc. Electrochemical sensor
US5972199A (en) 1995-10-11 1999-10-26 E. Heller & Company Electrochemical analyte sensors using thermostable peroxidase
US5855613A (en) 1995-10-13 1999-01-05 Islet Sheet Medical, Inc. Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change
US5711861A (en) 1995-11-22 1998-01-27 Ward; W. Kenneth Device for monitoring changes in analyte concentration
WO1997019188A1 (en) 1995-11-22 1997-05-29 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
US6063637A (en) 1995-12-13 2000-05-16 California Institute Of Technology Sensors for sugars and other metal binding analytes
JP3316820B2 (ja) 1995-12-28 2002-08-19 シィグナス インコーポレィティド 被験者の生理的分析物の継続モニタリング装置及び方法
US5833603A (en) 1996-03-13 1998-11-10 Lipomatrix, Inc. Implantable biosensing transponder
US20010011711A1 (en) * 1996-05-03 2001-08-09 Graham Nicholson Container for nuclear fuel transportation
US5776324A (en) 1996-05-17 1998-07-07 Encelle, Inc. Electrochemical biosensors
US5964261A (en) 1996-05-29 1999-10-12 Baxter International Inc. Implantation assembly
CA2259254C (en) 1996-07-08 2008-02-19 Animas Corporation Implantable sensor and system for in vivo measurement and control of fluid constituent levels
JP2943700B2 (ja) 1996-07-10 1999-08-30 日本電気株式会社 バイオセンサ
US6325978B1 (en) 1998-08-04 2001-12-04 Ntc Technology Inc. Oxygen monitoring and apparatus
US6054142A (en) 1996-08-01 2000-04-25 Cyto Therapeutics, Inc. Biocompatible devices with foam scaffolds
US5804048A (en) * 1996-08-15 1998-09-08 Via Medical Corporation Electrode assembly for assaying glucose
DE19642453C2 (de) 1996-10-15 1998-07-23 Bosch Gmbh Robert Anordnung für Gassensorelektroden
DK0944731T3 (da) * 1996-11-14 2006-05-22 Radiometer Medical Aps Enzymsensor
US5811487A (en) 1996-12-16 1998-09-22 Dow Corning Corporation Thickening silicones with elastomeric silicone polyethers
US5964993A (en) 1996-12-19 1999-10-12 Implanted Biosystems Inc. Glucose sensor
US5914026A (en) 1997-01-06 1999-06-22 Implanted Biosystems Inc. Implantable sensor employing an auxiliary electrode
US6093172A (en) 1997-02-05 2000-07-25 Minimed Inc. Injector for a subcutaneous insertion set
US5851197A (en) 1997-02-05 1998-12-22 Minimed Inc. Injector for a subcutaneous infusion set
US6607509B2 (en) 1997-12-31 2003-08-19 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US6891317B2 (en) 2001-05-22 2005-05-10 Sri International Rolled electroactive polymers
US6208894B1 (en) 1997-02-26 2001-03-27 Alfred E. Mann Foundation For Scientific Research And Advanced Bionics System of implantable devices for monitoring and/or affecting body parameters
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US7657297B2 (en) 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
US7192450B2 (en) * 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6741877B1 (en) 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
US20050033132A1 (en) 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US6558321B1 (en) 1997-03-04 2003-05-06 Dexcom, Inc. Systems and methods for remote monitoring and modulation of medical devices
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
FR2760962B1 (fr) 1997-03-20 1999-05-14 Sillonville Francis Klefstad Systeme d'assistance et de surveillance medicale a distance
US5961451A (en) 1997-04-07 1999-10-05 Motorola, Inc. Noninvasive apparatus having a retaining member to retain a removable biosensor
US6059946A (en) * 1997-04-14 2000-05-09 Matsushita Electric Industrial Co., Ltd. Biosensor
US5944661A (en) * 1997-04-16 1999-08-31 Giner, Inc. Potential and diffusion controlled solid electrolyte sensor for continuous measurement of very low levels of transdermal alcohol
AT404992B (de) 1997-04-17 1999-04-26 Avl List Gmbh Sensor zur bestimmung eines enzymsubstrates
US6115634A (en) 1997-04-30 2000-09-05 Medtronic, Inc. Implantable medical device and method of manufacture
US5779665A (en) 1997-05-08 1998-07-14 Minimed Inc. Transdermal introducer assembly
US6093167A (en) 1997-06-16 2000-07-25 Medtronic, Inc. System for pancreatic stimulation and glucose measurement
EP0990151A2 (de) 1997-06-16 2000-04-05 ELAN CORPORATION, Plc Verfahren zum kalibrieren und testen eines sensors für in vivo messung eines analytes, und vorrichtungen zum gebrauch dergleichen verfahren
US6013711A (en) 1997-06-18 2000-01-11 Ck Witco Corporation Hydrophilic polysiloxane compositions
US5861019A (en) 1997-07-25 1999-01-19 Medtronic Inc. Implantable medical device microstrip telemetry antenna
US5871514A (en) 1997-08-01 1999-02-16 Medtronic, Inc. Attachment apparatus for an implantable medical device employing ultrasonic energy
GB9717906D0 (en) 1997-08-23 1997-10-29 Univ Manchester Sensor Devices And Analytical Methods
US6731976B2 (en) 1997-09-03 2004-05-04 Medtronic, Inc. Device and method to measure and communicate body parameters
US6259937B1 (en) 1997-09-12 2001-07-10 Alfred E. Mann Foundation Implantable substrate sensor
US5999848A (en) 1997-09-12 1999-12-07 Alfred E. Mann Foundation Daisy chainable sensors and stimulators for implantation in living tissue
US5917346A (en) 1997-09-12 1999-06-29 Alfred E. Mann Foundation Low power current to frequency converter circuit for use in implantable sensors
AU9599498A (en) * 1997-09-30 1999-04-23 M-Biotech, Inc. Biosensor
US6585763B1 (en) 1997-10-14 2003-07-01 Vascusense, Inc. Implantable therapeutic device and method
US6296615B1 (en) 1999-03-05 2001-10-02 Data Sciences International, Inc. Catheter with physiological sensor
US5967986A (en) 1997-11-25 1999-10-19 Vascusense, Inc. Endoluminal implant with fluid flow sensing capability
US6409674B1 (en) 1998-09-24 2002-06-25 Data Sciences International, Inc. Implantable sensor with wireless communication
US6088608A (en) 1997-10-20 2000-07-11 Alfred E. Mann Foundation Electrochemical sensor and integrity tests therefor
US6119028A (en) * 1997-10-20 2000-09-12 Alfred E. Mann Foundation Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces
US6081736A (en) * 1997-10-20 2000-06-27 Alfred E. Mann Foundation Implantable enzyme-based monitoring systems adapted for long term use
US6104280A (en) 1997-10-20 2000-08-15 Micron Technology, Inc. Method of manufacturing and testing an electronic device, and an electronic device
CA2484271C (en) 1997-12-31 2007-04-24 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US6103033A (en) 1998-03-04 2000-08-15 Therasense, Inc. Process for producing an electrochemical biosensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6013113A (en) 1998-03-06 2000-01-11 Wilson Greatbatch Ltd. Slotted insulator for unsealed electrode edges in electrochemical cells
US6587705B1 (en) * 1998-03-13 2003-07-01 Lynn Kim Biosensor, iontophoretic sampling system, and methods of use thereof
US5904708A (en) 1998-03-19 1999-05-18 Medtronic, Inc. System and method for deriving relative physiologic signals
GB9805896D0 (en) 1998-03-20 1998-05-13 Eglise David Remote analysis system
JP3104672B2 (ja) 1998-03-31 2000-10-30 日本電気株式会社 電流検出型センサ素子およびその製造方法
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
US6175767B1 (en) * 1998-04-01 2001-01-16 James H. Doyle, Sr. Multichannel implantable inner ear stimulator
US6537318B1 (en) 1998-04-06 2003-03-25 Konjac Technologies, Llc Use of glucomannan hydrocolloid as filler material in prostheses
US6241863B1 (en) 1998-04-27 2001-06-05 Harold G. Monbouquette Amperometric biosensors based on redox enzymes
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
EP1077634B1 (de) 1998-05-13 2003-07-30 Cygnus, Inc. Überwachung physiologischer analyte
WO1999058050A1 (en) 1998-05-13 1999-11-18 Cygnus, Inc. Signal processing for measurement of physiological analytes
US6129757A (en) 1998-05-18 2000-10-10 Scimed Life Systems Implantable members for receiving therapeutically useful compositions
US7540875B2 (en) 1998-06-01 2009-06-02 Avatar Design & Development, Inc. Surgical cutting tool with automatically retractable blade assembly
US6187062B1 (en) 1998-06-16 2001-02-13 Alcatel Current collection through thermally sprayed tabs at the ends of a spirally wound electrochemical cell
US6248067B1 (en) 1999-02-05 2001-06-19 Minimed Inc. Analyte sensor and holter-type monitor system and method of using the same
ES2306525T3 (es) 1998-08-26 2008-11-01 Sensors For Medicine And Science, Inc. Dispositivos de deteccion basados en optica.
US6201980B1 (en) 1998-10-05 2001-03-13 The Regents Of The University Of California Implantable medical sensor system
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6016448A (en) 1998-10-27 2000-01-18 Medtronic, Inc. Multilevel ERI for implantable medical devices
US6156013A (en) 1998-11-04 2000-12-05 Mahurkar; Sakharam D. Safety syringe
US6364865B1 (en) 1998-11-13 2002-04-02 Elan Pharma International Limited Drug delivery systems and methods
US20030099682A1 (en) * 1998-11-20 2003-05-29 Francis Moussy Apparatus and method for control of tissue/implant interactions
US6497729B1 (en) 1998-11-20 2002-12-24 The University Of Connecticut Implant coating for control of tissue/implant interactions
US6066083A (en) * 1998-11-27 2000-05-23 Syntheon Llc Implantable brachytherapy device having at least partial deactivation capability
US6447448B1 (en) 1998-12-31 2002-09-10 Ball Semiconductor, Inc. Miniature implanted orthopedic sensors
US6309384B1 (en) 1999-02-01 2001-10-30 Adiana, Inc. Method and apparatus for tubal occlusion
US6424847B1 (en) 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
US6360888B1 (en) 1999-02-25 2002-03-26 Minimed Inc. Glucose sensor package system
US6230059B1 (en) 1999-03-17 2001-05-08 Medtronic, Inc. Implantable monitor
US6285897B1 (en) * 1999-04-07 2001-09-04 Endonetics, Inc. Remote physiological monitoring system
US6189536B1 (en) 1999-04-15 2001-02-20 Medtronic Inc. Method for protecting implantable devices
CA2369336A1 (en) 1999-04-22 2000-11-02 Cygnus, Inc. Hydrogel in an iontophoretic device to measure glucose
US7371400B2 (en) 2001-01-02 2008-05-13 The General Hospital Corporation Multilayer device for tissue engineering
US6475750B1 (en) 1999-05-11 2002-11-05 M-Biotech, Inc. Glucose biosensor
US6300002B1 (en) 1999-05-13 2001-10-09 Moltech Power Systems, Inc. Notched electrode and method of making same
US6546268B1 (en) 1999-06-02 2003-04-08 Ball Semiconductor, Inc. Glucose sensor
JP4801301B2 (ja) 1999-06-18 2011-10-26 アボット ダイアベティス ケア インコーポレイテッド 物質移動が制限された生体内分析物センサー
US6991643B2 (en) * 2000-12-20 2006-01-31 Usgi Medical Inc. Multi-barbed device for retaining tissue in apposition and methods of use
US6368274B1 (en) 1999-07-01 2002-04-09 Medtronic Minimed, Inc. Reusable analyte sensor site and method of using the same
US7247138B2 (en) * 1999-07-01 2007-07-24 Medtronic Minimed, Inc. Reusable analyte sensor site and method of using the same
US6413393B1 (en) 1999-07-07 2002-07-02 Minimed, Inc. Sensor including UV-absorbing polymer and method of manufacture
US20020019330A1 (en) * 1999-08-11 2002-02-14 Richard Murray Novel methods of diagnosis of angiogenesis, compositions, and methods of screening for angiogenesis modulators
US6471689B1 (en) 1999-08-16 2002-10-29 Thomas Jefferson University Implantable drug delivery catheter system with capillary interface
US6346583B1 (en) 1999-08-25 2002-02-12 General Electric Company Polar solvent compatible polyethersiloxane elastomers
US6312469B1 (en) 1999-09-13 2001-11-06 Medtronic Inc. Lamina prosthesis for delivery of medical treatment
US6343225B1 (en) * 1999-09-14 2002-01-29 Implanted Biosystems, Inc. Implantable glucose sensor
US6541107B1 (en) 1999-10-25 2003-04-01 Dow Corning Corporation Nanoporous silicone resins having low dielectric constants
US6517508B1 (en) * 1999-11-03 2003-02-11 Dsu Medical Corporation Set for blood processing
US6527729B1 (en) 1999-11-10 2003-03-04 Pacesetter, Inc. Method for monitoring patient using acoustic sensor
JP3426549B2 (ja) 1999-11-12 2003-07-14 本田技研工業株式会社 排気管の接続構造
GB9928071D0 (en) * 1999-11-29 2000-01-26 Polybiomed Ltd Blood compatible medical articles
AU1939801A (en) 1999-12-01 2001-06-12 Selective Genetics, Inc. In situ bioreactors and methods of use thereof
US6520997B1 (en) 1999-12-08 2003-02-18 Baxter International Inc. Porous three dimensional structure
US6974437B2 (en) 2000-01-21 2005-12-13 Medtronic Minimed, Inc. Microprocessor controlled ambulatory medical apparatus with hand held communication device
US6895263B2 (en) * 2000-02-23 2005-05-17 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US6743253B2 (en) 2000-02-29 2004-06-01 Biomod Surfaces Polyurethane-sealed biocompatible device and method for its preparation
US6551496B1 (en) 2000-03-03 2003-04-22 Ysi Incorporated Microstructured bilateral sensor
GB2367661B (en) * 2000-03-09 2004-11-24 Ibm A method and system for managing objects
US6365670B1 (en) 2000-03-10 2002-04-02 Wacker Silicones Corporation Organopolysiloxane gels for use in cosmetics
US6405066B1 (en) 2000-03-17 2002-06-11 The Regents Of The University Of California Implantable analyte sensor
AU2001263022A1 (en) 2000-05-12 2001-11-26 Therasense, Inc. Electrodes with multilayer membranes and methods of using and making the electrodes
US6442413B1 (en) * 2000-05-15 2002-08-27 James H. Silver Implantable sensor
US6459917B1 (en) 2000-05-22 2002-10-01 Ashok Gowda Apparatus for access to interstitial fluid, blood, or blood plasma components
WO2001090733A1 (en) 2000-05-23 2001-11-29 Radiometer Medical A/S A sensor membrane, a method for the preparation thereof, a sensor and a layered membrane structure for such sensor
US6991652B2 (en) 2000-06-13 2006-01-31 Burg Karen J L Tissue engineering composite
US6773565B2 (en) * 2000-06-22 2004-08-10 Kabushiki Kaisha Riken NOx sensor
US6400974B1 (en) 2000-06-29 2002-06-04 Sensors For Medicine And Science, Inc. Implanted sensor processing system and method for processing implanted sensor output
US6569521B1 (en) 2000-07-06 2003-05-27 3M Innovative Properties Company Stretch releasing pressure sensitive adhesive tape and articles
US6477392B1 (en) 2000-07-14 2002-11-05 Futrex Inc. Calibration of near infrared quantitative measurement device using optical measurement cross-products
US6683535B1 (en) 2000-08-09 2004-01-27 Alderon Industries, Llc Water detection system and method
EP1702635B1 (de) 2000-11-09 2008-01-16 Insulet Corporation Gerät zur transkutanen Abgabe von Medikamenten
US6695860B1 (en) 2000-11-13 2004-02-24 Isense Corp. Transcutaneous sensor insertion device
US6642015B2 (en) 2000-12-29 2003-11-04 Minimed Inc. Hydrophilic polymeric material for coating biosensors
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6793802B2 (en) * 2001-01-04 2004-09-21 Tyson Bioresearch, Inc. Biosensors having improved sample application and measuring properties and uses thereof
US7128904B2 (en) * 2001-01-16 2006-10-31 The Regents Of The University Of Michigan Material containing metal ion ligand complex producing nitric oxide in contact with blood
US6926670B2 (en) 2001-01-22 2005-08-09 Integrated Sensing Systems, Inc. Wireless MEMS capacitive sensor for physiologic parameter measurement
US6547839B2 (en) 2001-01-23 2003-04-15 Skc Co., Ltd. Method of making an electrochemical cell by the application of polysiloxane onto at least one of the cell components
US7014610B2 (en) 2001-02-09 2006-03-21 Medtronic, Inc. Echogenic devices and methods of making and using such devices
US6721587B2 (en) 2001-02-15 2004-04-13 Regents Of The University Of California Membrane and electrode structure for implantable sensor
WO2002072167A1 (en) 2001-03-13 2002-09-19 Implant Sciences Corporation. Drug eluting encapsulated stent
FR2822383B1 (fr) 2001-03-23 2004-12-17 Perouse Lab Prothese pour reconstruction plastique a proprietes d'hydrophilicite ameliorees, et procede pour leur obtention
US6379622B1 (en) * 2001-04-11 2002-04-30 Motorola, Inc. Sensor incorporating a quantum dot as a reference
US6454710B1 (en) 2001-04-11 2002-09-24 Motorola, Inc. Devices and methods for monitoring an analyte
US6528584B2 (en) * 2001-04-12 2003-03-04 The University Of Akron Multi-component polymeric networks containing poly(ethylene glycol)
US6613379B2 (en) 2001-05-08 2003-09-02 Isense Corp. Implantable analyte sensor
US6793632B2 (en) * 2001-06-12 2004-09-21 Lifescan, Inc. Percutaneous biological fluid constituent sampling and measurement devices and methods
US6501976B1 (en) 2001-06-12 2002-12-31 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
JP2003022761A (ja) * 2001-07-06 2003-01-24 Matsushita Electric Ind Co Ltd 電子銃及びそれを用いた陰極線管並びに電子銃の製造方法
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US20030025361A1 (en) * 2001-07-31 2003-02-06 Liu Lausan Chung-Hsin Chair folding structure
US6913626B2 (en) 2001-08-14 2005-07-05 Mcghan Jim J. Medical implant having bioabsorbable textured surface
US7025760B2 (en) 2001-09-07 2006-04-11 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US6809507B2 (en) 2001-10-23 2004-10-26 Medtronic Minimed, Inc. Implantable sensor electrodes and electronic circuitry
US6705833B2 (en) 2001-11-15 2004-03-16 Hewlett-Packard Development Company, L.P. Airflow flapper valve
US20040030294A1 (en) 2001-11-28 2004-02-12 Mahurkar Sakharam D. Retractable needle single use safety syringe
US6952604B2 (en) * 2001-12-21 2005-10-04 Becton, Dickinson And Company Minimally-invasive system and method for monitoring analyte levels
US7018336B2 (en) 2001-12-27 2006-03-28 Medtronic Minimed, Inc. Implantable sensor flush sleeve
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
DE60334365D1 (de) 2002-03-22 2010-11-11 Animas Technologies Llc Leistungsverbesserung einer analytenüberwachungsvorrichtung
US7863038B2 (en) * 2002-03-29 2011-01-04 Board Of Regents, The University Of Texas System Implantable biosensor from stratified nanostructured membranes
AU2003233468A1 (en) 2002-04-05 2003-10-27 Eyelab Group, Llc Monitoring blood substances using self-sampled tears
US7153265B2 (en) 2002-04-22 2006-12-26 Medtronic Minimed, Inc. Anti-inflammatory biosensor for reduced biofouling and enhanced sensor performance
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
WO2003101862A1 (en) 2002-05-31 2003-12-11 Dow Corning Toray Silicone Co.,Ltd. Cartridge for moisture-curable sealant
US6835387B2 (en) * 2002-06-11 2004-12-28 Scimed Life Systems, Inc. Sustained release of superoxide dismutase mimics from implantable or insertable medical devices
EP1518123B1 (de) * 2002-06-28 2008-10-29 November Aktiengesellschaft Gesellschaft für Molekulare Medizin Vorrichtung und verfahren zum elektrochemischen nachweis
US7233649B2 (en) * 2002-07-12 2007-06-19 Utstarcom, Inc. Faster modem method and apparatus
US20040010207A1 (en) 2002-07-15 2004-01-15 Flaherty J. Christopher Self-contained, automatic transcutaneous physiologic sensing system
US20040068230A1 (en) 2002-07-24 2004-04-08 Medtronic Minimed, Inc. System for providing blood glucose measurements to an infusion device
US20050272989A1 (en) 2004-06-04 2005-12-08 Medtronic Minimed, Inc. Analyte sensors and methods for making and using them
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
US6965791B1 (en) 2003-03-26 2005-11-15 Sorenson Medical, Inc. Implantable biosensor system, apparatus and method
AU2004224308B2 (en) * 2003-03-27 2009-09-17 Purdue Research Foundation Metallic nanoparticles as orthopedic biomaterial
US7134999B2 (en) * 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US7875293B2 (en) * 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
WO2005010518A1 (en) 2003-07-23 2005-02-03 Dexcom, Inc. Rolled electrode array and its method for manufacture
JP2007500336A (ja) 2003-07-25 2007-01-11 デックスコム・インコーポレーテッド 電気化学センサーに用いる電極システム
WO2005012871A2 (en) 2003-07-25 2005-02-10 Dexcom, Inc. Increasing bias for oxygen production in an electrode system
JP4708342B2 (ja) 2003-07-25 2011-06-22 デックスコム・インコーポレーテッド 埋設可能な装置に用いる酸素増大膜システム
US7108778B2 (en) 2003-07-25 2006-09-19 Dexcom, Inc. Electrochemical sensors including electrode systems with increased oxygen generation
US8060173B2 (en) 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US20050090607A1 (en) * 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
US7364592B2 (en) * 2004-02-12 2008-04-29 Dexcom, Inc. Biointerface membrane with macro-and micro-architecture
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US20050245799A1 (en) 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US20060015020A1 (en) 2004-07-06 2006-01-19 Dexcom, Inc. Systems and methods for manufacture of an analyte-measuring device including a membrane system
US7946984B2 (en) 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
US20080242961A1 (en) 2004-07-13 2008-10-02 Dexcom, Inc. Transcutaneous analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US20060016700A1 (en) * 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US8060174B2 (en) 2005-04-15 2011-11-15 Dexcom, Inc. Analyte sensing biointerface
WO2006113618A1 (en) 2005-04-15 2006-10-26 Dexcom, Inc. Analyte sensing biointerface
US7725148B2 (en) * 2005-09-23 2010-05-25 Medtronic Minimed, Inc. Sensor with layered electrodes

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WO2005025634A2 (en) 2005-03-24
EP1624908B8 (de) 2011-06-15
WO2005025634A3 (en) 2005-10-06
US20200375515A1 (en) 2020-12-03
US20060204536A1 (en) 2006-09-14
US20140275900A1 (en) 2014-09-18
WO2005025634A9 (en) 2005-07-07
EP1624908B1 (de) 2011-01-05
US20050031689A1 (en) 2005-02-10
JP2006525853A (ja) 2006-11-16
US20060198864A1 (en) 2006-09-07
US7875293B2 (en) 2011-01-25
EP1624908A2 (de) 2006-02-15
ATE494018T1 (de) 2011-01-15

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8327 Change in the person/name/address of the patent owner

Owner name: DEXCOM, INC., SAN DIEGO, CALIF., US

8381 Inventor (new situation)

Inventor name: CARR-BRENDEL, VICTORIA, PLEASANTON, CA 94566, US

Inventor name: MARKOVIC, DUBRAVKA, SAN DIEGO, CA 92122, US

Inventor name: TAPSAK, MARK, ORANGEVILLE, PA 17859, US

Inventor name: BRAUKER, JAMES H., SAN DIEGO, CALIF., US

Inventor name: SHULTS, MARK, MADISON, WIS., US