DE602005018763D1 - Dopamin-agonisten-kombinationstherapie mit sedativa zur verbesserung der schlafqualität - Google Patents
Dopamin-agonisten-kombinationstherapie mit sedativa zur verbesserung der schlafqualitätInfo
- Publication number
- DE602005018763D1 DE602005018763D1 DE602005018763T DE602005018763T DE602005018763D1 DE 602005018763 D1 DE602005018763 D1 DE 602005018763D1 DE 602005018763 T DE602005018763 T DE 602005018763T DE 602005018763 T DE602005018763 T DE 602005018763T DE 602005018763 D1 DE602005018763 D1 DE 602005018763D1
- Authority
- DE
- Germany
- Prior art keywords
- optically pure
- dopamine agonist
- preferred
- sedative agent
- desmethylzopiclone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54541304P | 2004-02-18 | 2004-02-18 | |
PCT/US2005/003937 WO2005079851A2 (en) | 2004-02-18 | 2005-02-07 | Dopamine-agonist combination therapy with sedatives for improving sleep quality |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005018763D1 true DE602005018763D1 (de) | 2010-02-25 |
Family
ID=34886149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005018763T Active DE602005018763D1 (de) | 2004-02-18 | 2005-02-07 | Dopamin-agonisten-kombinationstherapie mit sedativa zur verbesserung der schlafqualität |
Country Status (10)
Country | Link |
---|---|
US (2) | US20050267176A1 (de) |
EP (1) | EP1742624B1 (de) |
JP (1) | JP2007523165A (de) |
AT (1) | ATE454140T1 (de) |
AU (2) | AU2005215376B2 (de) |
CA (1) | CA2556870C (de) |
DE (1) | DE602005018763D1 (de) |
DK (1) | DK1742624T3 (de) |
ES (1) | ES2337700T3 (de) |
WO (1) | WO2005079851A2 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2004305563C1 (en) * | 2003-12-11 | 2011-07-07 | Sunovion Pharmaceuticals Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
ATE454140T1 (de) | 2004-02-18 | 2010-01-15 | Sepracor Inc | Dopamin-agonisten-kombinationstherapie mit sedativa zur verbesserung der schlafqualität |
CA2677470A1 (en) | 2004-04-05 | 2005-10-20 | Sepracor Inc. | Methods of treatment using eszopiclone |
TW200630368A (en) * | 2004-10-18 | 2006-09-01 | Neurocrine Biosciences Inc | Hydrate of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and processes and methods related thereto |
US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
BRPI0607017B8 (pt) | 2005-04-06 | 2021-05-25 | Adamas Pharmaceuticals Inc | composição farmacêutica compreendendo memantina e donezepil, e seu uso para o tratamento de condições relacionadas ao snc |
AU2006264317B2 (en) * | 2005-07-06 | 2012-02-23 | Sunovion Pharmaceuticals Inc. | Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
US20070270590A1 (en) * | 2006-04-20 | 2007-11-22 | Marioara Mendelovici | Methods for preparing eszopiclone crystalline form a, substantially pure eszopiclone and optically enriched eszopiclone |
US20080045547A1 (en) * | 2006-07-07 | 2008-02-21 | Lippa Arnold S | Salts And Co-Crystals of Pyrazolopyrimidine Compounds, Compositions Thereof And Methods For Their Production And Use |
EP1987815A1 (de) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Im Mund-Nasen-Rachenraum verabreichbare pharmazeutische Zusammensetzungen enthaltend Dopaminagonisten zur Vorbeugung und/oder Behandlung von unruhigen Gliedmassen |
WO2008150741A1 (en) * | 2007-06-04 | 2008-12-11 | Drugtech Corporation | Controlled release dopamine agonist compositions |
EP2020403A1 (de) | 2007-08-02 | 2009-02-04 | Esteve Quimica, S.A. | Verfahren zur Auflösung von Zopiclon und Zwischenprodukten |
US8269005B2 (en) * | 2007-12-19 | 2012-09-18 | Sunovion Pharmaceuticals Inc. | L-malate salts of 6-(5-chloro-2-Pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-Oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine |
US8268832B2 (en) * | 2007-12-19 | 2012-09-18 | Sunovion Pharmaceuticals Inc. | Maleate salts of 6-(5-chloro-2-Pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine |
US8212036B2 (en) | 2007-12-19 | 2012-07-03 | Sunovion Pharmaceuticals Inc. | Maleate salts of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine |
US8198278B2 (en) | 2007-12-19 | 2012-06-12 | Sunovion Pharmaceuticals Inc. | Besylate salts of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine |
US8198277B2 (en) * | 2007-12-19 | 2012-06-12 | Sunovion Pharmaceuticals Inc. | L-malate salts of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine |
RU2011122601A (ru) * | 2008-11-06 | 2012-12-20 | Байотай Терапис, Инк. | Лечение синдрома беспокойных ног и нарушений сна |
MX353752B (es) * | 2009-01-20 | 2018-01-26 | Los Angeles Biomedical Res Inst Harbor Ucla Medical Ct | Los ácidos sórbico y benzoico y sus derivados aumentan la actividad de un neurofármaco. |
CA2750059C (en) * | 2009-01-30 | 2014-11-18 | Sunovion Pharmaceuticals Inc. | Coated tablets of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine and methods for measuring effectiveness of coating |
CN106389381A (zh) | 2009-12-02 | 2017-02-15 | 阿达玛斯医药公司 | 金刚烷胺组合物及其使用方法 |
NZ602274A (en) | 2010-04-30 | 2014-05-30 | Teikoku Pharma Usa Inc | Propynylaminoindan transdermal compositions |
JP5906302B2 (ja) | 2011-03-24 | 2016-04-20 | テイコク ファーマ ユーエスエー インコーポレーテッド | 作用剤層および作用剤変換層を含む経皮組成物 |
EP2776020B1 (de) | 2011-11-09 | 2019-09-11 | Teikoku Seiyaku Co., Ltd. | Verfahren zur behandlung von neoplasmen der haut |
US9616123B1 (en) * | 2012-03-05 | 2017-04-11 | Robert L. Knobler | Method and compound for treatment of menopausal symptoms |
BR112015007872A2 (pt) | 2012-11-02 | 2017-07-04 | Teikoku Pharma Usa Inc | composições transdermais de propinilaminoindano |
WO2014204933A1 (en) | 2013-06-17 | 2014-12-24 | Adamas Pharmaceuticals, Inc. | Amantadine compositions and methods of use |
MX2018001720A (es) * | 2015-08-11 | 2018-09-06 | Ovid Therapeutics Inc | Metodos de sedacion y formulacion parenteral para uso durante el tratamiento de cuidados criticos. |
WO2017027249A1 (en) * | 2015-08-11 | 2017-02-16 | Ovid Therapeutics Inc. | Methods of sedation and parenteral formulation for use during critical care treatment |
TWI736635B (zh) | 2016-06-13 | 2021-08-21 | 心悅生醫股份有限公司 | 苯甲酸鋰之共晶及其用途 |
EP3468944B1 (de) | 2016-06-13 | 2022-11-16 | Syneurx International (Taiwan) Corp. | Co-kristalle von natriumbenzoat und verwendungen davon |
IL304011A (en) * | 2016-08-31 | 2023-08-01 | Taro Pharma Ind | Topical formulations of phenoldopam for the treatment of skin problems |
WO2019040748A1 (en) | 2017-08-24 | 2019-02-28 | Adamas Pharma, Llc | AMANTADINE COMPOSITIONS, THEIR PREPARATION, AND METHODS OF USE |
US20190247331A1 (en) | 2018-02-15 | 2019-08-15 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
US10213394B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
US10213393B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság | Composition and method for treating neurological disease |
CN116966129A (zh) | 2019-03-08 | 2023-10-31 | 塔罗制药工业有限公司 | 稳定的局部用非诺多泮组合物 |
SG11202112822VA (en) * | 2019-04-22 | 2021-12-30 | Robert Knobler | Non-hormonal treatment of hot flashes |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK270278A (da) * | 1977-06-20 | 1978-12-21 | Krogsgaard Larsen P | Cycliske aminosyrer |
FR2492382A1 (fr) | 1980-10-22 | 1982-04-23 | Synthelabo | Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique |
US4505029A (en) * | 1981-03-23 | 1985-03-19 | General Electric Company | Semiconductor device with built-up low resistance contact |
US4419345A (en) * | 1981-07-20 | 1983-12-06 | Kinetic Systems, Inc. | Sleep-inducing pharmaceutical composition and method |
DE3228351C2 (de) * | 1982-07-29 | 1985-07-25 | Merckle GmbH, 7902 Blaubeuren | Arzneimittel zur Behandlung von Schlafstörungen |
US4654347A (en) | 1983-06-23 | 1987-03-31 | American Cyanamid Company | Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones |
US4626538A (en) | 1983-06-23 | 1986-12-02 | American Cyanamid Company | [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines |
US4847256A (en) | 1986-10-16 | 1989-07-11 | American Cyanamid Company | 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo(1,5-A)-pyrimidines |
FR2606410B1 (fr) | 1986-11-07 | 1989-02-24 | Synthelabo | Imidazopyridines, leur preparation et leur application en therapeutique |
US5017616A (en) * | 1989-11-30 | 1991-05-21 | Jeffrey Askanazi | Method for improving ventilation during sleep and treating sleep related ventilation abnormalities |
FR2671800B1 (fr) * | 1991-01-17 | 1993-03-12 | Rhone Poulenc Rorer Sa | Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent. |
IT1251544B (it) * | 1991-05-13 | 1995-05-17 | Gabriele Biella | Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico |
US5786357A (en) * | 1991-12-02 | 1998-07-28 | Sepracor Inc. | Methods and compositions for treating sleep disorders, convulsive seizures and other disorders using optically pure (+) zopiclone |
US5538977A (en) | 1995-03-17 | 1996-07-23 | American Cyanamid Company | 3-Substituted-7-[3-(imidazol-1-yl)phenyl]-pyrazolo[1,5-a]pyrimidines |
IT1276522B1 (it) | 1995-04-07 | 1997-10-31 | Elena Benincasa | Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei |
DE19525598C2 (de) * | 1995-07-13 | 1997-09-25 | Max Planck Gesellschaft | Schlafmittel |
US5714607A (en) | 1995-12-01 | 1998-02-03 | American Cyanamid Company | Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide |
EP1011679B1 (de) * | 1997-03-12 | 2003-07-30 | Addex Pharmaceuticals SA | Verwendung von 8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepinen zur herstellung von pharmazeutischen zusammenstellungen zur behandlung von schlafstörungen |
WO1999063977A2 (en) * | 1998-06-09 | 1999-12-16 | Takeda Chemical Industries, Ltd. | Pharmaceutical combination comprising a tricyclic compound and at least one of zolpidem, zopiclone, triazolam and brotizolam for treating or preventing sleep disorders |
US6476078B2 (en) * | 1999-08-11 | 2002-11-05 | Sepracor, Inc. | Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction |
US6331571B1 (en) * | 1998-08-24 | 2001-12-18 | Sepracor, Inc. | Methods of treating and preventing attention deficit disorders |
SE9803760D0 (sv) * | 1998-11-04 | 1998-11-04 | Jan Hedner | Sätt att behandla och diagnostisera syndromet restless legs och motsvarande medel |
EP1005863A1 (de) | 1998-12-04 | 2000-06-07 | Synthelabo | Dosisformen mit gesteuerter Wirkstofffreigabe enthaltend ein kurzer wirkung Hypnotikum oder einem Salz davon |
PL359467A1 (en) | 1999-03-19 | 2004-08-23 | Knoll Gmbh | Method of treating sleep apnoea |
US6339086B1 (en) * | 1999-05-14 | 2002-01-15 | Swpracor, Inc. | Methods of making and using N-desmethylzopiclone |
US6231594B1 (en) * | 1999-08-11 | 2001-05-15 | Radiant Medical, Inc. | Method of controlling body temperature while reducing shivering |
US6258814B1 (en) * | 2000-10-13 | 2001-07-10 | Schering Corporation | Method of using cetirizine and pharmaceutical compositions containing the same for inducing sleep |
WO2002069974A1 (en) * | 2001-03-05 | 2002-09-12 | Andrew Holman | Administration of sleep restorative agents |
US20030087963A1 (en) * | 2001-09-13 | 2003-05-08 | Senanayake Chris H. | Methods of preparing and using 2-hydroxy derivatives of sibutramine and its metabolites |
WO2004037212A2 (en) * | 2002-10-24 | 2004-05-06 | Sepracor, Inc. | Compositions comprising zopiclone derivatives and methods of making and using the same |
US20040132826A1 (en) * | 2002-10-25 | 2004-07-08 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
US20050038042A1 (en) * | 2002-11-15 | 2005-02-17 | Jenet Codd | Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders |
WO2004112786A2 (en) | 2003-06-25 | 2004-12-29 | H. Lundbeck A/S | Gaboxadol for treating depression and other affective disorders |
US20050031688A1 (en) * | 2003-08-04 | 2005-02-10 | Ayala William J. | Positive wakeup pharmaceutical sleep system with compatible pre-bedtime administration |
AU2004305563C1 (en) * | 2003-12-11 | 2011-07-07 | Sunovion Pharmaceuticals Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
WO2005063248A1 (en) | 2003-12-22 | 2005-07-14 | Sepracor Inc. | Modafinil combination therapy for improving sleep quality |
EP1696959A2 (de) * | 2003-12-24 | 2006-09-06 | Sepracor, Inc. | Melatonin-kombinationstherapie zur verbesserung der schlafqualität |
US20050228052A1 (en) * | 2004-01-29 | 2005-10-13 | Barberich Timothy J | Methods of treating, preventing and managing a sleep disorder using (S)-didesmethylsibutramine |
ATE454140T1 (de) | 2004-02-18 | 2010-01-15 | Sepracor Inc | Dopamin-agonisten-kombinationstherapie mit sedativa zur verbesserung der schlafqualität |
CA2677470A1 (en) * | 2004-04-05 | 2005-10-20 | Sepracor Inc. | Methods of treatment using eszopiclone |
US7465729B2 (en) * | 2004-04-05 | 2008-12-16 | Sepracor Inc. | Methods of treatment of menopause and perimenopause using eszopiclone |
MX2008000249A (es) | 2005-07-06 | 2008-03-18 | Sepracor Inc | Combinaciones de eszopiclona y o-desmetilvenlafaxina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y cognitivos. |
AU2006264317B2 (en) * | 2005-07-06 | 2012-02-23 | Sunovion Pharmaceuticals Inc. | Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
EP1898915A4 (de) | 2005-07-06 | 2009-01-21 | Sepracor Inc | Kombinationen aus eszopiclon und einem antidepressivum |
WO2007005940A2 (en) | 2005-07-06 | 2007-01-11 | Sepracor Inc. | Combinations of eszopiclone and didesmethylsibutramine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
-
2005
- 2005-02-07 AT AT05732660T patent/ATE454140T1/de not_active IP Right Cessation
- 2005-02-07 WO PCT/US2005/003937 patent/WO2005079851A2/en active Application Filing
- 2005-02-07 US US11/052,719 patent/US20050267176A1/en not_active Abandoned
- 2005-02-07 JP JP2006554124A patent/JP2007523165A/ja active Pending
- 2005-02-07 DK DK05732660.5T patent/DK1742624T3/da active
- 2005-02-07 DE DE602005018763T patent/DE602005018763D1/de active Active
- 2005-02-07 EP EP05732660A patent/EP1742624B1/de active Active
- 2005-02-07 CA CA2556870A patent/CA2556870C/en not_active Expired - Fee Related
- 2005-02-07 AU AU2005215376A patent/AU2005215376B2/en active Active
- 2005-02-07 ES ES05732660T patent/ES2337700T3/es active Active
-
2009
- 2009-08-14 US US12/541,686 patent/US8877755B2/en active Active
-
2011
- 2011-04-15 AU AU2011201703A patent/AU2011201703A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2556870A1 (en) | 2005-09-01 |
WO2005079851A3 (en) | 2006-06-22 |
AU2011201703A1 (en) | 2011-05-12 |
EP1742624B1 (de) | 2010-01-06 |
CA2556870C (en) | 2014-01-28 |
EP1742624A2 (de) | 2007-01-17 |
AU2005215376B2 (en) | 2011-01-20 |
US20050267176A1 (en) | 2005-12-01 |
ES2337700T3 (es) | 2010-04-28 |
AU2005215376A1 (en) | 2005-09-01 |
JP2007523165A (ja) | 2007-08-16 |
ATE454140T1 (de) | 2010-01-15 |
WO2005079851A2 (en) | 2005-09-01 |
US20100004251A1 (en) | 2010-01-07 |
US8877755B2 (en) | 2014-11-04 |
DK1742624T3 (da) | 2010-03-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE602005018763D1 (de) | Dopamin-agonisten-kombinationstherapie mit sedativa zur verbesserung der schlafqualität | |
WO2005063297A3 (en) | Melatonin combination therapy for improving sleep quality | |
DK1970059T3 (da) | Lægemiddel med calciumdobesilat til behandling og profylakse af senelidelser | |
TW200616608A (en) | Memantine as adjunctive treatment to atypical antipsychotics in schizophrenia patients | |
HK1124546A1 (en) | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of mania and bipolar disorder | |
EA201070121A1 (ru) | Лекарственная форма, содержащая слитый белок glp-1-fc | |
UA102669C2 (en) | Use of dpp-iv inhibitors | |
CL2008001932A1 (es) | Compuestos derivados de 6-cicloamino-3-(piridin-4-il)imidazo[1,2-b]piridazina, inhibidores de cq1epsilon y/o ck1delta; procedimiento de preparacion; composicion farmaceutica que los comprende; y uso en el tratamiento de desordenes del sueno, trastorno del ritmo circadiano, cancer y enfermedad de alzheimer. | |
TW200800976A (en) | New compounds for the treatment of neurological, psychiatric or pain disorders | |
NO20050807L (no) | Farmasoytiske sammensetninger som innbefatter dekstrometorfan og kinidin for behandling av neurologiske forstyrrelser | |
EA200700407A1 (ru) | Производные хиназолина и их использования при лечении тромбоцитемии | |
HK1125039A1 (en) | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain | |
EA200970435A1 (ru) | Лечение общих расстройств развития | |
NO20055531L (no) | Preparat for forbedret kognisjon og hukommelse | |
ATE497809T1 (de) | Myricitrin verbindungen zur behandlung von schlafstörungen | |
DE60218193D1 (de) | Verwendung von 2-oxo-1-pyrrolidin-derivaten zur herstellung eines arzneimittels zur behandlung von dyskinesia | |
ATE516366T1 (de) | Regulierte aptamer-therapeutika | |
NO20073104L (no) | Anvendelse av en 5-HT6 agonist for behandling og forebygging av neurodegenerative forstyrrelser | |
CR7271A (es) | Formulaciones farmaceuticas novedosas a base de melatonina y compuestos similares para su uso en transtornos del sueno | |
ATE487480T1 (de) | Perhexilin zur behandlung von chronischer herzinsuffizienz | |
TW200603791A (en) | Compounds and compositions as cathepsin S inhibitors | |
ATE468852T1 (de) | Lofexidine zur intraspinalen anwendung | |
UA95094C2 (ru) | Применение бензоконденсированных гетероциклических сульфамидных производных для лечения маниакального синдрома и биполярного расстройства | |
JO2586B1 (en) | Use of different sulfamide derivatives combined with benzo ring for pain management | |
EA200970125A1 (ru) | Применение флумазенила в производстве лекарственного средства для лечения депрессивных расстройств |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |