DE602007009906D1 - Zusammensetzung und Gerät zur Knochenwiederherstellung - Google Patents

Zusammensetzung und Gerät zur Knochenwiederherstellung

Info

Publication number
DE602007009906D1
DE602007009906D1 DE602007009906T DE602007009906T DE602007009906D1 DE 602007009906 D1 DE602007009906 D1 DE 602007009906D1 DE 602007009906 T DE602007009906 T DE 602007009906T DE 602007009906 T DE602007009906 T DE 602007009906T DE 602007009906 D1 DE602007009906 D1 DE 602007009906D1
Authority
DE
Germany
Prior art keywords
bone
composition
carrier
human
bone repair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007009906T
Other languages
English (en)
Inventor
Mukesh Kumar
Ned M Hamann
Michael D Leach
John Manocchio
Antonio Paul D
Daryl L Carter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomet Manufacturing LLC
Original Assignee
Biomet Manufacturing LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomet Manufacturing LLC filed Critical Biomet Manufacturing LLC
Publication of DE602007009906D1 publication Critical patent/DE602007009906D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • A61L27/365Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608Bone, e.g. demineralised bone matrix [DBM], bone powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3616Blood, e.g. platelet-rich plasma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/204Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
DE602007009906T 2006-04-19 2007-04-19 Zusammensetzung und Gerät zur Knochenwiederherstellung Active DE602007009906D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/407,409 US7670384B2 (en) 2004-10-14 2006-04-19 Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone

Publications (1)

Publication Number Publication Date
DE602007009906D1 true DE602007009906D1 (de) 2010-12-02

Family

ID=38754544

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007009906T Active DE602007009906D1 (de) 2006-04-19 2007-04-19 Zusammensetzung und Gerät zur Knochenwiederherstellung

Country Status (5)

Country Link
US (1) US7670384B2 (de)
EP (1) EP1891990B1 (de)
AT (1) ATE485064T1 (de)
DE (1) DE602007009906D1 (de)
ES (1) ES2352224T3 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081704A1 (en) * 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US7670384B2 (en) * 2004-10-14 2010-03-02 Biomet Manufacturing Corp. Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone
US9017381B2 (en) 2007-04-10 2015-04-28 Biomet Sports Medicine, Llc Adjustable knotless loops
US9801708B2 (en) 2004-11-05 2017-10-31 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US7905904B2 (en) 2006-02-03 2011-03-15 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US8118836B2 (en) 2004-11-05 2012-02-21 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US7749250B2 (en) 2006-02-03 2010-07-06 Biomet Sports Medicine, Llc Soft tissue repair assembly and associated method
US8303604B2 (en) 2004-11-05 2012-11-06 Biomet Sports Medicine, Llc Soft tissue repair device and method
US7601165B2 (en) 2006-09-29 2009-10-13 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable suture loop
US7909851B2 (en) 2006-02-03 2011-03-22 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US8128658B2 (en) 2004-11-05 2012-03-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to bone
US8088130B2 (en) 2006-02-03 2012-01-03 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8137382B2 (en) 2004-11-05 2012-03-20 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US8361113B2 (en) 2006-02-03 2013-01-29 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8298262B2 (en) 2006-02-03 2012-10-30 Biomet Sports Medicine, Llc Method for tissue fixation
US8597327B2 (en) 2006-02-03 2013-12-03 Biomet Manufacturing, Llc Method and apparatus for sternal closure
US8968364B2 (en) 2006-02-03 2015-03-03 Biomet Sports Medicine, Llc Method and apparatus for fixation of an ACL graft
US8562647B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for securing soft tissue to bone
US9078644B2 (en) 2006-09-29 2015-07-14 Biomet Sports Medicine, Llc Fracture fixation device
US8936621B2 (en) 2006-02-03 2015-01-20 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US9538998B2 (en) 2006-02-03 2017-01-10 Biomet Sports Medicine, Llc Method and apparatus for fracture fixation
US11259792B2 (en) 2006-02-03 2022-03-01 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US9149267B2 (en) 2006-02-03 2015-10-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8562645B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US10517587B2 (en) 2006-02-03 2019-12-31 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8652171B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Method and apparatus for soft tissue fixation
US8801783B2 (en) 2006-09-29 2014-08-12 Biomet Sports Medicine, Llc Prosthetic ligament system for knee joint
US11311287B2 (en) 2006-02-03 2022-04-26 Biomet Sports Medicine, Llc Method for tissue fixation
US11259794B2 (en) 2006-09-29 2022-03-01 Biomet Sports Medicine, Llc Method for implanting soft tissue
US8672969B2 (en) 2006-09-29 2014-03-18 Biomet Sports Medicine, Llc Fracture fixation device
US8500818B2 (en) 2006-09-29 2013-08-06 Biomet Manufacturing, Llc Knee prosthesis assembly with ligament link
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US8137354B2 (en) * 2007-04-25 2012-03-20 Biomet Sports Medicine, Llc Localized cartilage defect therapy
US20090005868A1 (en) * 2007-06-27 2009-01-01 Depuy Products, Inc. Osteogenic prosthesis, associated instrument, and associated method
EP2222348B1 (de) 2007-12-21 2013-07-03 RTI Biologics, Inc. Osteoinduktive kittmassen und verfahren zur herstellung derartiger kittmassen
KR101072732B1 (ko) * 2009-04-01 2011-10-11 국립암센터 이식골 성형 시스템 및 이를 이용한 이식골 성형 방법
GB0905859D0 (en) * 2009-04-04 2009-05-20 Common Services Agency Bone washing process
DE102009039665A1 (de) * 2009-09-02 2011-03-03 Aap Biomaterials Gmbh Hydroxylapatitmaterial sowie Verfahren zu dessen Herstellung
US20110082424A1 (en) * 2009-10-02 2011-04-07 Barnhouse Michael P Method and apparatus for bone graft insertion
US9492584B2 (en) 2009-11-25 2016-11-15 Difusion Technologies, Inc. Post-charging of zeolite doped plastics with antimicrobial metal ions
BR112012016027B1 (pt) 2009-12-11 2019-01-15 Difusion Technologies, Inc. método de produção de implantes antimicrobianos de polieteretercetona
RU2643915C2 (ru) 2010-05-07 2018-02-06 Дифьюжн Текнолоджиз, Инк. Медицинские имплантаты с повышенной гидрофильностью
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8343229B2 (en) 2010-07-16 2013-01-01 Ebi, Llc Textured bone block implants
JP2013542837A (ja) 2010-11-15 2013-11-28 ジンマー オーソバイオロジクス,インコーポレイティド 骨空隙充填剤
US9357991B2 (en) 2011-11-03 2016-06-07 Biomet Sports Medicine, Llc Method and apparatus for stitching tendons
US9357992B2 (en) 2011-11-10 2016-06-07 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
US9381013B2 (en) 2011-11-10 2016-07-05 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
US9155606B2 (en) 2012-03-20 2015-10-13 C. R. Bard, Inc. Method and apparatus for rehydration of lyophilized biologic materials
US9283089B2 (en) 2012-04-05 2016-03-15 Warsaw Orthopedic, Inc. Interbody bone implant device
US9730801B2 (en) 2012-04-17 2017-08-15 Warsaw Orthopedic, Inc. Interbody bone implant device
US9101606B2 (en) 2012-04-19 2015-08-11 Warsaw Orthopedic, Inc. Bone delivery system having a therapeutic agent
US9220608B2 (en) 2012-04-24 2015-12-29 Warsaw Orthopedic, Inc. Facet joint implant device
US8771368B2 (en) 2012-04-24 2014-07-08 William F. McKay Interspinous bone implant device
US9480567B2 (en) 2012-05-07 2016-11-01 Warsaw Orthopedic, Inc. Bone implants and methods comprising demineralized bone material
US9585764B2 (en) 2012-07-26 2017-03-07 Warsaw Orthopedic, Inc. Bone implant device
US10172651B2 (en) 2012-10-25 2019-01-08 Warsaw Orthopedic, Inc. Cortical bone implant
US9265609B2 (en) 2013-01-08 2016-02-23 Warsaw Orthopedic, Inc. Osteograft implant
US9174147B2 (en) 2013-03-05 2015-11-03 Nordson Corporation Device and method for removing gas from a mixture of biomaterials
US9604184B2 (en) 2013-03-06 2017-03-28 Orthovita, Inc. Mixing system and valve assembly
US9757119B2 (en) 2013-03-08 2017-09-12 Biomet Sports Medicine, Llc Visual aid for identifying suture limbs arthroscopically
US10172660B2 (en) 2013-03-13 2019-01-08 Nordson Corporation Assembly for dispensing biomaterial, plunger therefor, and related methods
US9918827B2 (en) 2013-03-14 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
KR101326609B1 (ko) * 2013-06-07 2013-11-20 (주)코리아덴탈솔루션 치아를 골 이식재로 처리하는 자동화 기계
US9763911B2 (en) * 2013-12-12 2017-09-19 Mayo Foundation For Medical Education And Research Prostacyclin compositions for regulation of fracture repair and bone formation
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
ITUB20153831A1 (it) * 2015-09-23 2017-03-23 St Zooprofilattico Sperimentale Della Lombardia E Dellemilia Romagna Bruno Ubertini Osso demineralizzato, suoi usi e procedimento per il suo ottenimento
US11090411B2 (en) 2016-01-28 2021-08-17 Warsaw Orthopedic, Inc. Electron beam irradiated osteoinductive bone implant
US11253630B2 (en) * 2016-04-22 2022-02-22 Vivex Biologics Group, Inc. Malleable demineralized bone composition and method of manufacture
AU2017204355B2 (en) 2016-07-08 2021-09-09 Mako Surgical Corp. Scaffold for alloprosthetic composite implant
WO2018129443A1 (en) * 2017-01-09 2018-07-12 Cook Biotech Incorporated Lyophilizer container and method of use thereof
CA3105619A1 (en) 2018-07-06 2020-01-09 Instant Systems, Inc. Sample container with peelable seal and access port
US10813676B2 (en) * 2018-08-29 2020-10-27 Warsaw Orthopedic, Inc. Bone material hydration devices and methods
US11890819B2 (en) 2021-03-24 2024-02-06 Instant Systems, Inc. Multi-chamber container for biological materials and compounded pharmaceuticals
WO2022261389A2 (en) 2021-06-11 2022-12-15 Instant Systems, Inc. Container for biological materials having multiple sealed portions
KR102527814B1 (ko) * 2021-07-22 2023-05-02 한스바이오메드 주식회사 탈회골 유래 담체가 도입된 골이식재 및 그 제조 방법

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1456469A (en) * 1921-03-10 1923-05-22 Becton Dickinson Co Syringe
US2541621A (en) * 1947-10-14 1951-02-13 Louis F Thompson Hypodermic syringe
US4172128A (en) * 1975-03-26 1979-10-23 Erhard Thiele Process of degrading and regenerating bone and tooth material and products
DE2657370C2 (de) * 1976-12-17 1982-11-11 Hans Dr.med. Dr.med.dent. 8000 München Scheicher Mittel zum Bedecken und/oder Ausfüllen von Knochendefekten
US4200478A (en) * 1978-05-30 1980-04-29 Anthony Jacino Glass break repair apparatus and method
US4277184A (en) * 1979-08-14 1981-07-07 Alan Solomon Disposable orthopedic implement and method
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4958622A (en) * 1983-05-11 1990-09-25 Selenke William M Hypodermic syringe for taking and transporting a specimen
US4789663A (en) * 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
US4698055A (en) * 1986-11-24 1987-10-06 Sealfon Andrew I Hypodermic syringe
US5073373A (en) * 1989-09-21 1991-12-17 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5290558A (en) * 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5236456A (en) * 1989-11-09 1993-08-17 Osteotech, Inc. Osteogenic composition and implant containing same
US5356629A (en) * 1991-07-12 1994-10-18 United States Surgical Corporation Composition for effecting bone repair
US5314476A (en) * 1992-02-04 1994-05-24 Osteotech, Inc. Demineralized bone particles and flowable osteogenic composition containing same
US5263991A (en) * 1992-10-21 1993-11-23 Biomet, Inc. Method for heating biocompatible implants in a thermal packaging line
US5531791A (en) * 1993-07-23 1996-07-02 Bioscience Consultants Composition for repair of defects in osseous tissues, method of making, and prosthesis
US5507813A (en) * 1993-12-09 1996-04-16 Osteotech, Inc. Shaped materials derived from elongate bone particles
US6180606B1 (en) * 1994-09-28 2001-01-30 Gensci Orthobiologics, Inc. Compositions with enhanced osteogenic potential, methods for making the same and uses thereof
US5707962A (en) * 1994-09-28 1998-01-13 Gensci Regeneration Sciences Inc. Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof
US5697932A (en) * 1994-11-09 1997-12-16 Osteonics Corp. Bone graft delivery system and method
US5562616A (en) * 1995-03-01 1996-10-08 Habley Medical Technology Corporation Semi-automatic reconstituting system for binary oncolytic pharmaceuticals
DE69735625T2 (de) 1996-01-17 2006-12-21 Osteotech, Inc. Verfahren zur herstellung flexibler schichten aus deminaralisierten,länglichen knochenpartikeln
US5697903A (en) * 1996-02-22 1997-12-16 Ultradent Products, Inc. Methods and apparatus for dispensing compositions
US5824084A (en) * 1996-07-03 1998-10-20 The Cleveland Clinic Foundation Method of preparing a composite bone graft
US6395017B1 (en) * 1996-11-15 2002-05-28 C. R. Bard, Inc. Endoprosthesis delivery catheter with sequential stage control
US5842786A (en) * 1997-03-07 1998-12-01 Solomon; Alan Method and device for mixing medical compositions
US20020098222A1 (en) * 1997-03-13 2002-07-25 John F. Wironen Bone paste
US5957166A (en) * 1997-06-16 1999-09-28 Fusion Medical Technologies, Inc. Method and apparatus for dispersing fluid into a material
US5908054A (en) * 1997-06-16 1999-06-01 Fusion Medical Technologies, Inc. Fluid dispersion and delivery assembly and method
US6062722A (en) * 1997-10-21 2000-05-16 Micron Communications, Inc. Fluid mixing and withdrawing methods
US20020076429A1 (en) 1998-01-28 2002-06-20 John F. Wironen Bone paste subjected to irradiative and thermal treatment
US20020018796A1 (en) * 1998-01-28 2002-02-14 John F. Wironen Thermally sterilized bone paste
US6458375B1 (en) * 1998-02-27 2002-10-01 Musculoskeletal Transplant Foundation Malleable paste with allograft bone reinforcement for filling bone defects
US6437018B1 (en) * 1998-02-27 2002-08-20 Musculoskeletal Transplant Foundation Malleable paste with high molecular weight buffered carrier for filling bone defects
US6326018B1 (en) * 1998-02-27 2001-12-04 Musculoskeletal Transplant Foundation Flexible sheet of demineralized bone
USRE38522E1 (en) * 1998-02-27 2004-05-25 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
US6030635A (en) * 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
US6019765A (en) * 1998-05-06 2000-02-01 Johnson & Johnson Professional, Inc. Morsellized bone allograft applicator device
WO2000045871A1 (en) * 1999-02-04 2000-08-10 Sdgi Holdings, Inc. Highly-mineralized osteogenic sponge compositions, and uses thereof
CA2362046A1 (en) 1999-02-04 2000-08-10 Sdgi Holdings, Inc. Osteogenic paste compositions and uses thereof
US6696073B2 (en) * 1999-02-23 2004-02-24 Osteotech, Inc. Shaped load-bearing osteoimplant and methods of making same
US6294187B1 (en) * 1999-02-23 2001-09-25 Osteotech, Inc. Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same
AU6406700A (en) * 1999-03-16 2000-10-04 Regeneration Technologies, Inc. Molded implants for orthopedic applications
US9387094B2 (en) * 2000-07-19 2016-07-12 Warsaw Orthopedic, Inc. Osteoimplant and method of making same
US6576249B1 (en) * 2000-11-13 2003-06-10 El Gendler Bone putty and method
US7175336B2 (en) * 2001-01-26 2007-02-13 Depuy Acromed, Inc. Graft delivery system
US6723131B2 (en) * 2001-02-28 2004-04-20 The Cleveland Clinic Foundation Composite bone marrow graft material with method and kit
US6648133B1 (en) * 2001-07-18 2003-11-18 Biomet, Inc. Device and method for hydrating and rehydrating orthopedic graft materials
US7132110B2 (en) * 2001-08-30 2006-11-07 Isotis Orthobiologics, Inc. Tissue repair compositions and methods for their manufacture and use
US7141054B2 (en) * 2003-02-03 2006-11-28 Biomet, Inc. Method and apparatus for intramedullary delivery of a material
US7077339B2 (en) * 2003-02-03 2006-07-18 Biomet, Inc. Spray applicator
US20050074476A1 (en) * 2003-10-03 2005-04-07 El Gendler Cartilidge and bone induction by artificially perforated organic bone matrix augmented by undifferentiated cells suspended in bone gel
US20060083769A1 (en) * 2004-10-14 2006-04-20 Mukesh Kumar Method and apparatus for preparing bone
US7670384B2 (en) * 2004-10-14 2010-03-02 Biomet Manufacturing Corp. Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone

Also Published As

Publication number Publication date
EP1891990A3 (de) 2008-04-23
US20060280803A1 (en) 2006-12-14
ES2352224T3 (es) 2011-02-16
US7670384B2 (en) 2010-03-02
EP1891990A2 (de) 2008-02-27
EP1891990B1 (de) 2010-10-20
ATE485064T1 (de) 2010-11-15

Similar Documents

Publication Publication Date Title
DE602007009906D1 (de) Zusammensetzung und Gerät zur Knochenwiederherstellung
DK1791532T3 (da) Sammensætning i mikropelletform med styret afgivelse af fysiologisk aktive stoffer, fremgangsmåde til deres fremstilling og anvendelse i den zootekniske sektor
DE112007003309A5 (de) Knochenimplantat sowie Set zur Herstellung von Knochenimplantaten
AU304245S (en) Artificial stone
DE602005010709D1 (de) Verfahren zur herstellung von pflanzenextrakten und heimtierfuttermitteln
AR051867A1 (es) Producto de suero y procedimiento
PL2061527T3 (pl) Naprawa tkanki chrzęstnej
AU313201S (en) Edible pet chew
ATE478626T1 (de) Zahnimplantat, insbesondere aus einem keramikmaterial
DE602005018428D1 (de) Verfahren und Gerät zur Knochenwiederherstellung
DE602006020682D1 (de) Synthetische Perlmutter, Verfahren und Vorrichtung zu ihrer Herstellung
DE602005026092D1 (de) Vorrichtung zur Herstellung von anorganischen sphärischen Teilchen
DE602004024902D1 (de) Verbesserte formulierung zur bereitstellung eines magensaftresitenten beschichtungsmaterials
ATE525091T1 (de) Zusammensetzungen und verfahren zur regulierten proteinexpression im darm
DE602005018419D1 (de) Wasserabsorbierende Harzzusammensetzung und Verfahren zur Herstellung derselben
AU313873S (en) A bath for animals
DE602004010367D1 (de) Vorrichtungen und zusammensetzungen mit bor und silikon zur verwendung in der neutronen-fang-therapie
AU318917S (en) Egg forming mould
DE602007002571D1 (de) Vorrichtung zur Herstellung von Lebensmitteln
AT503681A3 (de) Vorrichtung zur herstellung von formteilen mit mikrostrukturierter oberflache
RU2006144033A (ru) Способ получения продукта для регенерации воздуха
AU311742S (en) Grooming glove for animals
ATE514664T1 (de) Verfahren zur herstellung eines phosphorhaltigen düngemittels aus tiermehl
EP1992433A3 (de) Spritzgießform
DE602004005010D1 (de) Verfahren zur Herstellung von Fettsäuren mit den verbesserten Eigenschaften Geruch, Farbe und Hitzestabilität