DE60215497D1 - Analytische instrumente und biosensoren sowie verfahren zur erhöhung ihrer genauigkeit und einsatzdauer - Google Patents

Analytische instrumente und biosensoren sowie verfahren zur erhöhung ihrer genauigkeit und einsatzdauer

Info

Publication number
DE60215497D1
DE60215497D1 DE60215497T DE60215497T DE60215497D1 DE 60215497 D1 DE60215497 D1 DE 60215497D1 DE 60215497 T DE60215497 T DE 60215497T DE 60215497 T DE60215497 T DE 60215497T DE 60215497 D1 DE60215497 D1 DE 60215497D1
Authority
DE
Germany
Prior art keywords
biosensors
duration
accuracy
increasing
analytical instruments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60215497T
Other languages
English (en)
Other versions
DE60215497T2 (de
Inventor
Clarke Xu
Sohrab Mansouri
Vasile Cosofret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instrumentation Laboratory Co
Original Assignee
Instrumentation Laboratory Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instrumentation Laboratory Co filed Critical Instrumentation Laboratory Co
Publication of DE60215497D1 publication Critical patent/DE60215497D1/de
Application granted granted Critical
Publication of DE60215497T2 publication Critical patent/DE60215497T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/002Electrode membranes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/38Cleaning of electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/492Determining multiple analytes
DE60215497T 2001-05-31 2002-05-30 Analytische instrumente und biosensoren sowie verfahren zur erhöhung ihrer genauigkeit und einsatzdauer Expired - Lifetime DE60215497T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/871,885 US6872297B2 (en) 2001-05-31 2001-05-31 Analytical instruments, biosensors and methods thereof
US871885 2001-05-31
PCT/US2002/016818 WO2002097414A2 (en) 2001-05-31 2002-05-30 Analytical instruments and biosensors, and methods for increasing their accuracy and effective life

Publications (2)

Publication Number Publication Date
DE60215497D1 true DE60215497D1 (de) 2006-11-30
DE60215497T2 DE60215497T2 (de) 2007-07-05

Family

ID=25358380

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60215497T Expired - Lifetime DE60215497T2 (de) 2001-05-31 2002-05-30 Analytische instrumente und biosensoren sowie verfahren zur erhöhung ihrer genauigkeit und einsatzdauer
DE60226526T Expired - Lifetime DE60226526D1 (de) 2001-05-31 2002-05-30 Verfahren zur Wiederherstellung der funktionellen Eigenschaften eines elektrochemischen Sensors

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60226526T Expired - Lifetime DE60226526D1 (de) 2001-05-31 2002-05-30 Verfahren zur Wiederherstellung der funktionellen Eigenschaften eines elektrochemischen Sensors

Country Status (9)

Country Link
US (2) US6872297B2 (de)
EP (2) EP1739415B1 (de)
JP (2) JP4398722B2 (de)
AT (2) ATE394664T1 (de)
AU (1) AU2002318166B2 (de)
CA (2) CA2809149C (de)
DE (2) DE60215497T2 (de)
ES (2) ES2274059T3 (de)
WO (1) WO2002097414A2 (de)

Families Citing this family (129)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US6960466B2 (en) * 2001-05-31 2005-11-01 Instrumentation Laboratory Company Composite membrane containing a cross-linked enzyme matrix for a biosensor
US6872297B2 (en) * 2001-05-31 2005-03-29 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
ATE485766T1 (de) 2001-06-12 2010-11-15 Pelikan Technologies Inc Elektrisches betätigungselement für eine lanzette
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
ATE497731T1 (de) 2001-06-12 2011-02-15 Pelikan Technologies Inc Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute
WO2002100254A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
CA2448905C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Blood sampling apparatus and method
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
EP1277438A1 (de) * 2001-07-10 2003-01-22 Agilent Technologies, Inc. (a Delaware corporation) Pflegeplatz Diagnose und/oder Analyse System
AU2003256748B2 (en) * 2001-08-22 2007-12-06 Instrumentation Laboratory Company Compositions and method for reducing the rate of oxygen loss from aqueous solutions
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7569393B2 (en) 2002-06-28 2009-08-04 International Technidyne Corporation Analytical test cartridge; and, methods
US6794877B2 (en) * 2002-07-31 2004-09-21 International Technidyne Corporation Apparatus and method for analytical determinations
WO2004053483A2 (en) * 2002-12-11 2004-06-24 Instrumentation Laboratory Company Multi-analyte reference solutions
DE10259821B4 (de) * 2002-12-19 2006-03-09 Siemens Ag Bio-Chip
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US20040154933A1 (en) * 2003-02-11 2004-08-12 Instrumentation Laboratory Company Polymeric membranes for use in electrochemical sensors
US20040256227A1 (en) * 2003-02-11 2004-12-23 Jungwon Shin Electrochemical urea sensors and methods of making the same
ATE476137T1 (de) 2003-05-30 2010-08-15 Pelikan Technologies Inc Verfahren und vorrichtung zur injektion von flüssigkeit
WO2004107964A2 (en) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Blood harvesting device with electronic control
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
WO2005012873A2 (en) * 2003-07-25 2005-02-10 Dexcom, Inc. Electrode systems for electrochemical sensors
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
EP1671096A4 (de) 2003-09-29 2009-09-16 Pelikan Technologies Inc Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung
EP1680014A4 (de) 2003-10-14 2009-01-21 Pelikan Technologies Inc Verfahren und gerät für eine variable anwenderschnittstelle
DE10353938A1 (de) * 2003-11-18 2005-06-23 Fresenius Medical Care Deutschland Gmbh Sensorkarte zur Bestimmung von Analyten in Flüssigkeits- oder Gasproben und Verfahren zur Herstellung einer solchen Sensorkarte
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP1706026B1 (de) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Verfahren und vorrichtung zur verbesserung der fluidströmung und der probennahme
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (de) 2004-06-03 2010-09-29 Pelikan Technologies Inc Verfahren und gerät für eine flüssigkeitsentnahmenvorrichtung
US8343074B2 (en) * 2004-06-30 2013-01-01 Lifescan Scotland Limited Fluid handling devices
US7310544B2 (en) 2004-07-13 2007-12-18 Dexcom, Inc. Methods and systems for inserting a transcutaneous analyte sensor
US7608042B2 (en) * 2004-09-29 2009-10-27 Intellidx, Inc. Blood monitoring system
US20070191716A1 (en) * 2004-09-29 2007-08-16 Daniel Goldberger Blood monitoring system
US20060229531A1 (en) * 2005-02-01 2006-10-12 Daniel Goldberger Blood monitoring system
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
KR20080053460A (ko) * 2005-08-05 2008-06-13 어번 유니버시티 다중이온용 가역 가능한 전기화학 센서
US20080200838A1 (en) * 2005-11-28 2008-08-21 Daniel Goldberger Wearable, programmable automated blood testing system
US20070119710A1 (en) * 2005-11-28 2007-05-31 Daniel Goldberger Test substrate handling apparatus
US8173077B2 (en) * 2005-12-16 2012-05-08 The Curators Of The University Of Missouri Reusable PCR amplification system and method
US7291502B2 (en) * 2006-03-15 2007-11-06 Franco Wayne P Method for performing a non-invasive blood gas test
US8092385B2 (en) * 2006-05-23 2012-01-10 Intellidx, Inc. Fluid access interface
US20080021294A1 (en) * 2006-07-14 2008-01-24 Levin Paul D Disposable blood glucose sensor with internal pump
JP2008032395A (ja) * 2006-07-26 2008-02-14 Yokogawa Electric Corp 人工透析患者に対する血液診断方法および透析装置
US8173071B2 (en) 2006-08-29 2012-05-08 International Business Machines Corporation Micro-fluidic test apparatus and method
US20090188811A1 (en) * 2007-11-28 2009-07-30 Edwards Lifesciences Corporation Preparation and maintenance of sensors
ES2354850T3 (es) * 2008-01-07 2011-03-18 F. Hoffmann-La Roche Ag Casete de reactivos.
EP2265324B1 (de) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integriertes System zur Messung von Analyten
US8523797B2 (en) * 2008-05-08 2013-09-03 Hospira, Inc. Automated point-of-care fluid testing device and method of using the same
US8181531B2 (en) * 2008-06-27 2012-05-22 Edwin Carlen Accessible stress-based electrostatic monitoring of chemical reactions and binding
US9011670B2 (en) * 2008-08-14 2015-04-21 The Charles Stark Draper Laboratory, Inc. Three-dimensional metal ion sensor arrays on printed circuit boards
JP5261136B2 (ja) * 2008-10-31 2013-08-14 横河電機株式会社 血液分析方法
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8753290B2 (en) * 2009-03-27 2014-06-17 Intellectual Inspiration, Llc Fluid transfer system and method
US9166139B2 (en) * 2009-05-14 2015-10-20 The Neothermal Energy Company Method for thermally cycling an object including a polarizable material
US9237864B2 (en) 2009-07-02 2016-01-19 Dexcom, Inc. Analyte sensors and methods of manufacturing same
US9351677B2 (en) 2009-07-02 2016-05-31 Dexcom, Inc. Analyte sensor with increased reference capacity
US20110054284A1 (en) * 2009-08-28 2011-03-03 Edwards Lifesciences Corporation Anti-Coagulant Calibrant Infusion Fluid Source
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
CN102843969B (zh) * 2010-04-16 2015-05-13 爱科来株式会社 传感器及干涉物质的除去方法
US9700851B2 (en) * 2010-05-13 2017-07-11 Waveform Technologies, Inc. Phenol crosslink for sensor membrane
CN107523441A (zh) * 2011-07-12 2017-12-29 诺维信公司 储存稳定的酶颗粒
WO2013039672A1 (en) * 2011-09-13 2013-03-21 Siemens Healthcare Diagnostics Inc. Patient serum/plasma sample resistivity for electrolyte result verification
JP5809969B2 (ja) * 2011-12-28 2015-11-11 株式会社堀場製作所 イオン分析装置
US9788765B2 (en) 2012-09-28 2017-10-17 Dexcom, Inc. Zwitterion surface modifications for continuous sensors
US9162021B2 (en) * 2012-10-22 2015-10-20 Baxter International Inc. Integrated water testing system and method for ultra-low total chlorine detection
CN105228522B (zh) * 2013-03-14 2018-06-26 萨诺智能公司 用于生物监测的人体上的微传感器
US10820860B2 (en) 2013-03-14 2020-11-03 One Drop Biosensor Technologies, Llc On-body microsensor for biomonitoring
US9828620B2 (en) * 2013-06-28 2017-11-28 Verily Life Sciences Llc Porous polymeric formulation prepared using monomer
US20150133861A1 (en) 2013-11-11 2015-05-14 Kevin P. McLennan Thermal management system and method for medical devices
US10595754B2 (en) 2014-03-13 2020-03-24 Sano Intelligence, Inc. System for monitoring body chemistry
US20150257687A1 (en) 2014-03-13 2015-09-17 Sano Intelligence, Inc. System for monitoring body chemistry
EP3177258A4 (de) 2014-08-08 2018-09-12 Fremon Scientific, Inc. Intelligenter beutel zur messung physiologischer und/oder physikalischer parameter von beuteln mit einer biologischen substanz
US10143795B2 (en) 2014-08-18 2018-12-04 Icu Medical, Inc. Intravenous pole integrated power, control, and communication system and method for an infusion pump
AU2016267763B2 (en) 2015-05-26 2021-07-08 Icu Medical, Inc. Disposable infusion fluid delivery device for programmable large volume drug delivery
US20200209180A1 (en) * 2015-08-14 2020-07-02 Razzberry, Inc. Solid state electrodes, methods of making, and methods of use in sensing
US20180284049A1 (en) 2015-09-30 2018-10-04 Siemens Healthcare Diagnostics Inc. Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein
CA3006271C (en) * 2015-11-27 2020-09-15 Radiometer Medical Aps An outer layer for enzyme sensors
DK178929B9 (en) * 2015-12-15 2017-06-26 Radiometer Medical Aps A Bag Containing a Reference Fluid
DE102016217257A1 (de) * 2016-09-09 2018-03-15 Robert Bosch Gmbh Wegwerf-Teststreifen für multiplen Heim-Blutanalytentest
EP3559664B1 (de) 2016-12-23 2020-12-09 Radiometer Medical ApS Mehrfach verwendbare sensoranordnung für körperflüssigkeiten
EP3625554A1 (de) * 2017-05-15 2020-03-25 Analog Devices Global Unlimited Company Integrierter ionensensor und verfahren
JP2019128261A (ja) * 2018-01-25 2019-08-01 学校法人東北学院 使い捨て型バイオセンサチップおよびこれを装着するバイオセンサ
US10866173B2 (en) 2018-05-07 2020-12-15 Fremon Scientific, Inc. Thawing biological substances
JP7082691B2 (ja) 2019-04-05 2022-06-08 インストゥルメンテーション ラボラトリー カンパニー クレアチニン/クレアチンセンサーのキャリブレーション精度を改善する方法
KR102532761B1 (ko) * 2019-08-02 2023-05-16 바이오나임 코포레이션 마이크로 바이오센서의 측정 간섭 감소 방법
USD939079S1 (en) 2019-08-22 2021-12-21 Icu Medical, Inc. Infusion pump
JP7414999B2 (ja) 2019-12-11 2024-01-16 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド 塩化物イオン選択性センサーを形成するための光硬化性試薬ならびにその製造方法および使用方法
USD988882S1 (en) 2021-04-21 2023-06-13 Informed Data Systems Inc. Sensor assembly
US20230304960A1 (en) 2022-02-09 2023-09-28 Instrumentation Laboratory Company Sensor for measuring ionized magnesium

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4109505A (en) * 1974-07-22 1978-08-29 Primary Children's Hospital Automated blood analysis system
US4214968A (en) * 1978-04-05 1980-07-29 Eastman Kodak Company Ion-selective electrode
JPS57118152A (en) * 1981-01-14 1982-07-22 Matsushita Electric Ind Co Ltd Enzyme electrode
US4355105A (en) * 1981-03-30 1982-10-19 Miles Laboratories, Inc. Glutaraldehyde/polyethylenimine immobilization of whole microbial cells
US4390627A (en) * 1981-10-26 1983-06-28 Miles Laboratories, Inc. Immobilization of the sucrose mutase in whole cells of protaminobacter rubrum
DE3223885A1 (de) * 1982-06-26 1983-12-29 Basf Ag, 6700 Ludwigshafen Makroporoese, hydrophile traeger fuer enzyme
CA1223638A (en) 1983-05-05 1987-06-30 Graham Davis Assay systems utilising more than one enzyme
US4760024A (en) * 1983-08-10 1988-07-26 Miles Inc. Immobilization of enzymes
CA1210717A (en) 1983-08-10 1986-09-02 Oreste J. Lantero, Jr. Immobilization of biocatalysts
JPS60155959A (ja) 1984-01-25 1985-08-16 Matsushita Electric Works Ltd バイオセンサを用いた測定法
US4734184A (en) * 1985-08-29 1988-03-29 Diamond Sensor Systems, Inc. Self-activating hydratable solid-state electrode apparatus
JPS6288953A (ja) * 1985-10-15 1987-04-23 Matsushita Electric Works Ltd 酵素電極
US4713165A (en) 1986-07-02 1987-12-15 Ilex Corporation Sensor having ion-selective electrodes
JPS6350748A (ja) * 1986-08-20 1988-03-03 Sanyo Electric Co Ltd 酵素電極システム
GB2194843A (en) 1986-09-08 1988-03-16 Cambridge Life Sciences Enzyme electrode membrane and method of making same
US4810351A (en) * 1986-09-18 1989-03-07 Technicon Instruments Corporation Carbonate selective membrane and electrode
US5540828A (en) * 1987-06-08 1996-07-30 Yacynych; Alexander Method for making electrochemical sensors and biosensors having a polymer modified surface
US5286364A (en) * 1987-06-08 1994-02-15 Rutgers University Surface-modified electochemical biosensor
JPS6423155A (en) * 1987-07-17 1989-01-25 Daikin Ind Ltd Electrode refreshing device for biosensor
JPS6428555A (en) 1987-07-24 1989-01-31 Terumo Corp Enzyme sensor
US5212050A (en) 1988-11-14 1993-05-18 Mier Randall M Method of forming a permselective layer
US5766934A (en) * 1989-03-13 1998-06-16 Guiseppi-Elie; Anthony Chemical and biological sensors having electroactive polymer thin films attached to microfabricated devices and possessing immobilized indicator moieties
US5312762A (en) * 1989-03-13 1994-05-17 Guiseppi Elie Anthony Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte
EP0396788A1 (de) * 1989-05-08 1990-11-14 Dräger Nederland B.V. Verfahren und Sensor zur Messung des Glucosegehalts von Glucose enthaltenden Flüssigkeiten
US5352349A (en) * 1989-08-30 1994-10-04 Daikin Industries, Ltd. Method for reviving an electrode of a biosensor
CA2024234C (en) 1989-08-30 2001-03-13 Tomoyuki Inamoto Method and apparatus for reviving an electrode of a biosensor
JPH07119727B2 (ja) 1989-08-30 1995-12-20 ダイキン工業株式会社 バイオセンサの電極リフレッシュ方法およびその装置
US5078854A (en) * 1990-01-22 1992-01-07 Mallinckrodt Sensor Systems, Inc. Polarographic chemical sensor with external reference electrode
IE904444A1 (en) * 1990-12-10 1992-06-17 Stephen J Harris Ion-selective electrodes
US5162077A (en) * 1990-12-10 1992-11-10 Bryan Avron I Device for in situ cleaning a fouled sensor membrane of deposits
US5262305A (en) * 1991-03-04 1993-11-16 E. Heller & Company Interferant eliminating biosensors
JP2995927B2 (ja) * 1991-06-20 1999-12-27 エヌオーケー株式会社 グルコ−スバイオセンサ
AU3274693A (en) 1991-12-31 1993-07-28 Abbott Laboratories Composite membrane
JPH0643130A (ja) * 1992-07-24 1994-02-18 Daikin Ind Ltd 複合型固定化酵素膜
ZA938555B (en) * 1992-11-23 1994-08-02 Lilly Co Eli Technique to improve the performance of electrochemical sensors
FI94179C (fi) * 1993-03-03 1995-07-25 Kone Oy Menetelmä ja laitteisto ammoniakkipitoisuuden määrittämiseksi sekä menetelmä ilmaisimen valmistamiseksi
CA2157503A1 (en) * 1993-03-05 1994-09-15 John M. Riviello Pulsed electrochemical detection using polymer electroactive electrodes
ATE256179T1 (de) * 1993-09-01 2003-12-15 Genencor Int Verfahren zur herstellung von immobilisierten enzymkonjugaten und so erhaltene immobilisierte enzymkonjugate
GB9320782D0 (en) * 1993-10-08 1993-12-01 Univ Leeds Innovations Ltd Stabilising of proteins on solution
US5781455A (en) * 1993-11-02 1998-07-14 Kyoto Daiichi Kagaku Co., Ltd. Article of manufacture comprising computer usable medium for a portable blood sugar value measuring apparatus
DE19500354C1 (de) * 1995-01-07 1995-10-19 Inst Chemo Biosensorik Verfahren zur Herstellung von Durchflußreaktionskartuschen für bioanalytische Systeme und Bioreaktoren
US5798030A (en) 1995-05-17 1998-08-25 Australian Membrane And Biotechnology Research Institute Biosensor membranes
WO1997015827A1 (en) 1995-10-25 1997-05-01 Wilkins Ebtisam S Coated wire sensor
EP0771867A3 (de) 1995-10-30 1998-09-02 Ciba-Geigy Japan Limited Enzymelektrode
US5653862A (en) * 1996-04-15 1997-08-05 Dade Chemistry Systems Inc. Biochemical sensor device and method
JP2000507457A (ja) * 1996-11-14 2000-06-20 ラジオメーター・メディカル・アクティーゼルスカブ 酵素センサ
AT404992B (de) * 1997-04-17 1999-04-26 Avl List Gmbh Sensor zur bestimmung eines enzymsubstrates
CA2294610A1 (en) * 1997-06-16 1998-12-23 George Moshe Katz Methods of calibrating and testing a sensor for in vivo measurement of an analyte and devices for use in such methods
US5906921A (en) 1997-09-29 1999-05-25 Matsushita Electric Industrial Co., Ltd. Biosensor and method for quantitative measurement of a substrate using the same
US6030827A (en) * 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
GB9808517D0 (en) * 1998-04-23 1998-06-17 Aea Technology Plc Electrical sensor
JP3214563B2 (ja) * 1998-07-02 2001-10-02 日本電気株式会社 酵素電極およびそれを用いたバイオセンサ、測定器
SE9901446L (sv) 1999-04-22 2000-03-27 Btg Kaelle Inventing Ab Sätt för rengöring av elektroder i mätutrustningar
KR100360774B1 (ko) * 1999-12-27 2002-11-13 한국전자통신연구원 효소전극센서 및 그 제조방법
MXPA02008500A (es) 2000-03-02 2004-05-05 Accentus Plc Sensor quimico.
US6652720B1 (en) * 2001-05-31 2003-11-25 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
US6872297B2 (en) 2001-05-31 2005-03-29 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof

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JP2008256725A (ja) 2008-10-23
AU2002318166B2 (en) 2007-01-11
CA2448705C (en) 2013-11-05
EP1739415A3 (de) 2007-02-28
EP1739415B1 (de) 2008-05-07
DE60226526D1 (de) 2008-06-19
CA2809149A1 (en) 2002-12-05
JP4398722B2 (ja) 2010-01-13
ATE343126T1 (de) 2006-11-15
JP4812813B2 (ja) 2011-11-09
CA2448705A1 (en) 2002-12-05
US20030000833A1 (en) 2003-01-02
WO2002097414A3 (en) 2003-10-16
WO2002097414A2 (en) 2002-12-05
EP1395812B1 (de) 2006-10-18
EP1739415A2 (de) 2007-01-03
JP2004528578A (ja) 2004-09-16
US20050126929A1 (en) 2005-06-16
US7455760B2 (en) 2008-11-25
ES2307254T3 (es) 2008-11-16
ATE394664T1 (de) 2008-05-15
US6872297B2 (en) 2005-03-29
ES2274059T3 (es) 2007-05-16
DE60215497T2 (de) 2007-07-05
ES2307254T8 (es) 2021-04-05
EP1395812A2 (de) 2004-03-10

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