DE60215497D1 - Analytische instrumente und biosensoren sowie verfahren zur erhöhung ihrer genauigkeit und einsatzdauer - Google Patents

Analytische instrumente und biosensoren sowie verfahren zur erhöhung ihrer genauigkeit und einsatzdauer

Info

Publication number
DE60215497D1
DE60215497D1 DE60215497T DE60215497T DE60215497D1 DE 60215497 D1 DE60215497 D1 DE 60215497D1 DE 60215497 T DE60215497 T DE 60215497T DE 60215497 T DE60215497 T DE 60215497T DE 60215497 D1 DE60215497 D1 DE 60215497D1
Authority
DE
Germany
Prior art keywords
biosensors
duration
accuracy
increasing
analytical instruments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60215497T
Other languages
English (en)
Other versions
DE60215497T2 (de
Inventor
Clarke Xu
Sohrab Mansouri
Vasile Cosofret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instrumentation Laboratory Co
Original Assignee
Instrumentation Laboratory Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instrumentation Laboratory Co filed Critical Instrumentation Laboratory Co
Application granted granted Critical
Publication of DE60215497D1 publication Critical patent/DE60215497D1/de
Publication of DE60215497T2 publication Critical patent/DE60215497T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/002Electrode membranes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/38Cleaning of electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/492Determining multiple analytes
DE60215497T 2001-05-31 2002-05-30 Analytische instrumente und biosensoren sowie verfahren zur erhöhung ihrer genauigkeit und einsatzdauer Expired - Lifetime DE60215497T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US871885 1986-06-09
US09/871,885 US6872297B2 (en) 2001-05-31 2001-05-31 Analytical instruments, biosensors and methods thereof
PCT/US2002/016818 WO2002097414A2 (en) 2001-05-31 2002-05-30 Analytical instruments and biosensors, and methods for increasing their accuracy and effective life

Publications (2)

Publication Number Publication Date
DE60215497D1 true DE60215497D1 (de) 2006-11-30
DE60215497T2 DE60215497T2 (de) 2007-07-05

Family

ID=25358380

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60226526T Expired - Lifetime DE60226526D1 (de) 2001-05-31 2002-05-30 Verfahren zur Wiederherstellung der funktionellen Eigenschaften eines elektrochemischen Sensors
DE60215497T Expired - Lifetime DE60215497T2 (de) 2001-05-31 2002-05-30 Analytische instrumente und biosensoren sowie verfahren zur erhöhung ihrer genauigkeit und einsatzdauer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60226526T Expired - Lifetime DE60226526D1 (de) 2001-05-31 2002-05-30 Verfahren zur Wiederherstellung der funktionellen Eigenschaften eines elektrochemischen Sensors

Country Status (9)

Country Link
US (2) US6872297B2 (de)
EP (2) EP1739415B1 (de)
JP (2) JP4398722B2 (de)
AT (2) ATE394664T1 (de)
AU (1) AU2002318166B2 (de)
CA (2) CA2448705C (de)
DE (2) DE60226526D1 (de)
ES (2) ES2307254T3 (de)
WO (1) WO2002097414A2 (de)

Families Citing this family (129)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US6872297B2 (en) * 2001-05-31 2005-03-29 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
US6960466B2 (en) 2001-05-31 2005-11-01 Instrumentation Laboratory Company Composite membrane containing a cross-linked enzyme matrix for a biosensor
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
ES2357887T3 (es) 2001-06-12 2011-05-03 Pelikan Technologies Inc. Aparato para mejorar la tasa de éxito de obtención de sangre a partir de una punción capilar.
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
EP1404232B1 (de) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Gerät und verfahren zur entnahme von blutproben
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
EP1277438A1 (de) * 2001-07-10 2003-01-22 Agilent Technologies, Inc. (a Delaware corporation) Pflegeplatz Diagnose und/oder Analyse System
US8858434B2 (en) 2004-07-13 2014-10-14 Dexcom, Inc. Transcutaneous analyte sensor
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7708701B2 (en) 2002-04-19 2010-05-04 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7569393B2 (en) 2002-06-28 2009-08-04 International Technidyne Corporation Analytical test cartridge; and, methods
JP4672366B2 (ja) * 2002-07-26 2011-04-20 インストゥルメンテイション ラボラトリー カンパニー 水溶液から酸素損失の速度を減少するための組成物および方法
US6794877B2 (en) * 2002-07-31 2004-09-21 International Technidyne Corporation Apparatus and method for analytical determinations
US7422903B2 (en) * 2002-12-11 2008-09-09 Instrumentation Laboratory Company Multi-analyte reference solutions
DE10259821B4 (de) 2002-12-19 2006-03-09 Siemens Ag Bio-Chip
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US20040256227A1 (en) * 2003-02-11 2004-12-23 Jungwon Shin Electrochemical urea sensors and methods of making the same
US20040154933A1 (en) * 2003-02-11 2004-08-12 Instrumentation Laboratory Company Polymeric membranes for use in electrochemical sensors
ES2347248T3 (es) 2003-05-30 2010-10-27 Pelikan Technologies Inc. Procedimiento y aparato para la inyeccion de fluido.
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
JP2007500336A (ja) * 2003-07-25 2007-01-11 デックスコム・インコーポレーテッド 電気化学センサーに用いる電極システム
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
DE10353938A1 (de) * 2003-11-18 2005-06-23 Fresenius Medical Care Deutschland Gmbh Sensorkarte zur Bestimmung von Analyten in Flüssigkeits- oder Gasproben und Verfahren zur Herstellung einer solchen Sensorkarte
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (de) 2004-06-03 2010-09-29 Pelikan Technologies Inc Verfahren und gerät für eine flüssigkeitsentnahmenvorrichtung
US8343074B2 (en) * 2004-06-30 2013-01-01 Lifescan Scotland Limited Fluid handling devices
US7608042B2 (en) * 2004-09-29 2009-10-27 Intellidx, Inc. Blood monitoring system
US20070191716A1 (en) * 2004-09-29 2007-08-16 Daniel Goldberger Blood monitoring system
US20060229531A1 (en) * 2005-02-01 2006-10-12 Daniel Goldberger Blood monitoring system
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
KR20080053460A (ko) * 2005-08-05 2008-06-13 어번 유니버시티 다중이온용 가역 가능한 전기화학 센서
US20080200838A1 (en) * 2005-11-28 2008-08-21 Daniel Goldberger Wearable, programmable automated blood testing system
US20070119710A1 (en) * 2005-11-28 2007-05-31 Daniel Goldberger Test substrate handling apparatus
WO2007078833A2 (en) * 2005-12-16 2007-07-12 The Curators Of The University Of Missouri Reusable pcr amplification system and method
US7291502B2 (en) * 2006-03-15 2007-11-06 Franco Wayne P Method for performing a non-invasive blood gas test
US8092385B2 (en) * 2006-05-23 2012-01-10 Intellidx, Inc. Fluid access interface
US20080021294A1 (en) * 2006-07-14 2008-01-24 Levin Paul D Disposable blood glucose sensor with internal pump
JP2008032395A (ja) * 2006-07-26 2008-02-14 Yokogawa Electric Corp 人工透析患者に対する血液診断方法および透析装置
US8173071B2 (en) * 2006-08-29 2012-05-08 International Business Machines Corporation Micro-fluidic test apparatus and method
US20090188811A1 (en) * 2007-11-28 2009-07-30 Edwards Lifesciences Corporation Preparation and maintenance of sensors
ES2354850T3 (es) * 2008-01-07 2011-03-18 F. Hoffmann-La Roche Ag Casete de reactivos.
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
US8523797B2 (en) * 2008-05-08 2013-09-03 Hospira, Inc. Automated point-of-care fluid testing device and method of using the same
US8181531B2 (en) * 2008-06-27 2012-05-22 Edwin Carlen Accessible stress-based electrostatic monitoring of chemical reactions and binding
US9011670B2 (en) * 2008-08-14 2015-04-21 The Charles Stark Draper Laboratory, Inc. Three-dimensional metal ion sensor arrays on printed circuit boards
JP5261136B2 (ja) * 2008-10-31 2013-08-14 横河電機株式会社 血液分析方法
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8753290B2 (en) * 2009-03-27 2014-06-17 Intellectual Inspiration, Llc Fluid transfer system and method
US9166139B2 (en) * 2009-05-14 2015-10-20 The Neothermal Energy Company Method for thermally cycling an object including a polarizable material
US9351677B2 (en) 2009-07-02 2016-05-31 Dexcom, Inc. Analyte sensor with increased reference capacity
US20110027458A1 (en) 2009-07-02 2011-02-03 Dexcom, Inc. Continuous analyte sensors and methods of making same
US20110054284A1 (en) * 2009-08-28 2011-03-03 Edwards Lifesciences Corporation Anti-Coagulant Calibrant Infusion Fluid Source
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
JP5785937B2 (ja) * 2010-04-16 2015-09-30 アークレイ株式会社 センサ及び干渉物質の除去方法
US9700851B2 (en) * 2010-05-13 2017-07-11 Waveform Technologies, Inc. Phenol crosslink for sensor membrane
EP2732018B1 (de) 2011-07-12 2017-01-04 Novozymes A/S Lagerstabile enzymgranulate
US9228975B2 (en) 2011-09-13 2016-01-05 Siemens Healthcare Diagnostics Inc. Patient serum/plasma sample resistivity for electrolyte result verification
JP5809969B2 (ja) * 2011-12-28 2015-11-11 株式会社堀場製作所 イオン分析装置
US9788765B2 (en) 2012-09-28 2017-10-17 Dexcom, Inc. Zwitterion surface modifications for continuous sensors
US9162021B2 (en) * 2012-10-22 2015-10-20 Baxter International Inc. Integrated water testing system and method for ultra-low total chlorine detection
US10820860B2 (en) 2013-03-14 2020-11-03 One Drop Biosensor Technologies, Llc On-body microsensor for biomonitoring
EP2972264A4 (de) 2013-03-14 2016-12-07 Sano Intelligence Inc Am körper getragener mikrosensor für bioüberwachung
US9828620B2 (en) * 2013-06-28 2017-11-28 Verily Life Sciences Llc Porous polymeric formulation prepared using monomer
US20150133861A1 (en) 2013-11-11 2015-05-14 Kevin P. McLennan Thermal management system and method for medical devices
US10595754B2 (en) 2014-03-13 2020-03-24 Sano Intelligence, Inc. System for monitoring body chemistry
US20150257685A1 (en) 2014-03-13 2015-09-17 Sano Intelligence, Inc. System for monitoring body chemistry
CA2957526C (en) * 2014-08-08 2023-03-28 Fremon Scientific, Inc. Smart bag used in sensing physiological and/or physical parameters of bags containing biological substance
US10143795B2 (en) 2014-08-18 2018-12-04 Icu Medical, Inc. Intravenous pole integrated power, control, and communication system and method for an infusion pump
ES2809505T3 (es) 2015-05-26 2021-03-04 Icu Medical Inc Dispositivo de administración de fluido de infusión desechable para la administración programable de fármacos de gran volumen
US20190049400A1 (en) * 2015-08-14 2019-02-14 Razzberry, Inc. Electrodes, and methods of use in detecting explosives and other volatile materials
CA2999995C (en) 2015-09-30 2021-08-24 Siemens Healthcare Diagnostics Inc. Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein
DK3380833T3 (da) 2015-11-27 2020-03-16 Radiometer Medical Aps Ydre lag til enzymsensorer
DK178929B9 (en) * 2015-12-15 2017-06-26 Radiometer Medical Aps A Bag Containing a Reference Fluid
DE102016217257A1 (de) * 2016-09-09 2018-03-15 Robert Bosch Gmbh Wegwerf-Teststreifen für multiplen Heim-Blutanalytentest
CN112698021A (zh) * 2016-12-23 2021-04-23 雷迪奥米特医学公司 用于体液的多次使用传感器组件
US20200072783A1 (en) * 2017-05-15 2020-03-05 Analog Devices Global Unlimited Company Integrated ion sensing apparatus and methods
JP2019128261A (ja) * 2018-01-25 2019-08-01 学校法人東北学院 使い捨て型バイオセンサチップおよびこれを装着するバイオセンサ
CN112512603A (zh) 2018-05-07 2021-03-16 弗莱蒙科学公司 解冻生物物质
DK3947708T3 (da) * 2019-04-05 2024-03-11 Instr Laboratory Co Fremgangsmåde og system til forbedret kalibrering af kreatinin/kreatin-sensorer
AU2020210303B2 (en) * 2019-08-02 2021-09-23 Bionime Corporation Micro Biosensor and Measuring Method Thereof
USD939079S1 (en) 2019-08-22 2021-12-21 Icu Medical, Inc. Infusion pump
JP7414999B2 (ja) 2019-12-11 2024-01-16 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド 塩化物イオン選択性センサーを形成するための光硬化性試薬ならびにその製造方法および使用方法
USD988882S1 (en) 2021-04-21 2023-06-13 Informed Data Systems Inc. Sensor assembly
WO2023154326A1 (en) 2022-02-09 2023-08-17 Instrumentation Laboratory Company Sensor for measuring ionized magnesium

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4109505A (en) * 1974-07-22 1978-08-29 Primary Children's Hospital Automated blood analysis system
US4214968A (en) 1978-04-05 1980-07-29 Eastman Kodak Company Ion-selective electrode
JPS57118152A (en) * 1981-01-14 1982-07-22 Matsushita Electric Ind Co Ltd Enzyme electrode
US4355105A (en) 1981-03-30 1982-10-19 Miles Laboratories, Inc. Glutaraldehyde/polyethylenimine immobilization of whole microbial cells
US4390627A (en) 1981-10-26 1983-06-28 Miles Laboratories, Inc. Immobilization of the sucrose mutase in whole cells of protaminobacter rubrum
DE3223885A1 (de) 1982-06-26 1983-12-29 Basf Ag, 6700 Ludwigshafen Makroporoese, hydrophile traeger fuer enzyme
CA1223638A (en) 1983-05-05 1987-06-30 Graham Davis Assay systems utilising more than one enzyme
US4760024A (en) 1983-08-10 1988-07-26 Miles Inc. Immobilization of enzymes
CA1210717A (en) 1983-08-10 1986-09-02 Oreste J. Lantero, Jr. Immobilization of biocatalysts
JPS60155959A (ja) 1984-01-25 1985-08-16 Matsushita Electric Works Ltd バイオセンサを用いた測定法
US4734184A (en) 1985-08-29 1988-03-29 Diamond Sensor Systems, Inc. Self-activating hydratable solid-state electrode apparatus
JPS6288953A (ja) * 1985-10-15 1987-04-23 Matsushita Electric Works Ltd 酵素電極
US4713165A (en) * 1986-07-02 1987-12-15 Ilex Corporation Sensor having ion-selective electrodes
JPS6350748A (ja) * 1986-08-20 1988-03-03 Sanyo Electric Co Ltd 酵素電極システム
GB2194843A (en) 1986-09-08 1988-03-16 Cambridge Life Sciences Enzyme electrode membrane and method of making same
US4810351A (en) 1986-09-18 1989-03-07 Technicon Instruments Corporation Carbonate selective membrane and electrode
US5540828A (en) 1987-06-08 1996-07-30 Yacynych; Alexander Method for making electrochemical sensors and biosensors having a polymer modified surface
US5286364A (en) 1987-06-08 1994-02-15 Rutgers University Surface-modified electochemical biosensor
JPS6423155A (en) * 1987-07-17 1989-01-25 Daikin Ind Ltd Electrode refreshing device for biosensor
JPS6428555A (en) 1987-07-24 1989-01-31 Terumo Corp Enzyme sensor
US5212050A (en) * 1988-11-14 1993-05-18 Mier Randall M Method of forming a permselective layer
US5766934A (en) * 1989-03-13 1998-06-16 Guiseppi-Elie; Anthony Chemical and biological sensors having electroactive polymer thin films attached to microfabricated devices and possessing immobilized indicator moieties
US5312762A (en) * 1989-03-13 1994-05-17 Guiseppi Elie Anthony Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte
EP0396788A1 (de) * 1989-05-08 1990-11-14 Dräger Nederland B.V. Verfahren und Sensor zur Messung des Glucosegehalts von Glucose enthaltenden Flüssigkeiten
JPH07119727B2 (ja) 1989-08-30 1995-12-20 ダイキン工業株式会社 バイオセンサの電極リフレッシュ方法およびその装置
DE69019088T2 (de) 1989-08-30 1995-11-30 Daikin Ind Ltd Verfahren und Apparat zur Erneuerung einer Elektrode eines Biosensors.
US5352349A (en) * 1989-08-30 1994-10-04 Daikin Industries, Ltd. Method for reviving an electrode of a biosensor
US5078854A (en) * 1990-01-22 1992-01-07 Mallinckrodt Sensor Systems, Inc. Polarographic chemical sensor with external reference electrode
US5162077A (en) * 1990-12-10 1992-11-10 Bryan Avron I Device for in situ cleaning a fouled sensor membrane of deposits
US5132345A (en) 1990-12-10 1992-07-21 Harris Stephen J Ion-selective electrodes
US5262305A (en) 1991-03-04 1993-11-16 E. Heller & Company Interferant eliminating biosensors
JP2995927B2 (ja) * 1991-06-20 1999-12-27 エヌオーケー株式会社 グルコ−スバイオセンサ
AU3274693A (en) * 1991-12-31 1993-07-28 Abbott Laboratories Composite membrane
JPH0643130A (ja) * 1992-07-24 1994-02-18 Daikin Ind Ltd 複合型固定化酵素膜
ZA938555B (en) 1992-11-23 1994-08-02 Lilly Co Eli Technique to improve the performance of electrochemical sensors
FI94179C (fi) * 1993-03-03 1995-07-25 Kone Oy Menetelmä ja laitteisto ammoniakkipitoisuuden määrittämiseksi sekä menetelmä ilmaisimen valmistamiseksi
US5403451A (en) 1993-03-05 1995-04-04 Riviello; John M. Method and apparatus for pulsed electrochemical detection using polymer electroactive electrodes
DE69433398T2 (de) 1993-09-01 2004-06-09 Genencor International, Inc., Palo Alto Verfahren zur Herstellung von immobilisierten Enzymkonjugaten und so erhaltene immobilisierte Enzymkonjugate
GB9320782D0 (en) 1993-10-08 1993-12-01 Univ Leeds Innovations Ltd Stabilising of proteins on solution
US5781455A (en) * 1993-11-02 1998-07-14 Kyoto Daiichi Kagaku Co., Ltd. Article of manufacture comprising computer usable medium for a portable blood sugar value measuring apparatus
DE19500354C1 (de) * 1995-01-07 1995-10-19 Inst Chemo Biosensorik Verfahren zur Herstellung von Durchflußreaktionskartuschen für bioanalytische Systeme und Bioreaktoren
US5798030A (en) * 1995-05-17 1998-08-25 Australian Membrane And Biotechnology Research Institute Biosensor membranes
WO1997015827A1 (en) 1995-10-25 1997-05-01 Wilkins Ebtisam S Coated wire sensor
EP0771867A3 (de) 1995-10-30 1998-09-02 Ciba-Geigy Japan Limited Enzymelektrode
US5653862A (en) 1996-04-15 1997-08-05 Dade Chemistry Systems Inc. Biochemical sensor device and method
DE69735127T2 (de) 1996-11-14 2006-08-31 Radiometer Medical Aps Enzymsensor
AT404992B (de) 1997-04-17 1999-04-26 Avl List Gmbh Sensor zur bestimmung eines enzymsubstrates
AU8031898A (en) * 1997-06-16 1999-01-04 Elan Medical Technologies Limited Methods of calibrating and testing a sensor for (in vivo) measurement of an analyte and devices for use in such methods
US5906921A (en) 1997-09-29 1999-05-25 Matsushita Electric Industrial Co., Ltd. Biosensor and method for quantitative measurement of a substrate using the same
US6030827A (en) 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
GB9808517D0 (en) * 1998-04-23 1998-06-17 Aea Technology Plc Electrical sensor
JP3214563B2 (ja) * 1998-07-02 2001-10-02 日本電気株式会社 酵素電極およびそれを用いたバイオセンサ、測定器
SE9901446L (sv) 1999-04-22 2000-03-27 Btg Kaelle Inventing Ab Sätt för rengöring av elektroder i mätutrustningar
KR100360774B1 (ko) 1999-12-27 2002-11-13 한국전자통신연구원 효소전극센서 및 그 제조방법
CA2404359A1 (en) 2000-03-02 2001-09-07 Andrew Derek Turner Chemical sensor
US6872297B2 (en) * 2001-05-31 2005-03-29 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
US6652720B1 (en) * 2001-05-31 2003-11-25 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof

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ES2274059T3 (es) 2007-05-16
CA2809149C (en) 2016-07-19
JP2004528578A (ja) 2004-09-16
ES2307254T8 (es) 2021-04-05
JP2008256725A (ja) 2008-10-23
DE60215497T2 (de) 2007-07-05
US20050126929A1 (en) 2005-06-16
WO2002097414A2 (en) 2002-12-05
US6872297B2 (en) 2005-03-29
CA2448705C (en) 2013-11-05
EP1395812B1 (de) 2006-10-18
ATE343126T1 (de) 2006-11-15
EP1739415B1 (de) 2008-05-07
EP1395812A2 (de) 2004-03-10
CA2809149A1 (en) 2002-12-05
CA2448705A1 (en) 2002-12-05
US20030000833A1 (en) 2003-01-02
DE60226526D1 (de) 2008-06-19
WO2002097414A3 (en) 2003-10-16
JP4398722B2 (ja) 2010-01-13
ES2307254T3 (es) 2008-11-16
US7455760B2 (en) 2008-11-25
JP4812813B2 (ja) 2011-11-09
EP1739415A3 (de) 2007-02-28
AU2002318166B2 (en) 2007-01-11
ATE394664T1 (de) 2008-05-15

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