DE60225172D1 - Transdermale transportvorrichtung mit mikronadeln - Google Patents

Transdermale transportvorrichtung mit mikronadeln

Info

Publication number
DE60225172D1
DE60225172D1 DE60225172T DE60225172T DE60225172D1 DE 60225172 D1 DE60225172 D1 DE 60225172D1 DE 60225172 T DE60225172 T DE 60225172T DE 60225172 T DE60225172 T DE 60225172T DE 60225172 D1 DE60225172 D1 DE 60225172D1
Authority
DE
Germany
Prior art keywords
needle
transport device
microned
pins
transdermal transport
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60225172T
Other languages
English (en)
Inventor
Aimee B Angel
Ian W Hunter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Application granted granted Critical
Publication of DE60225172D1 publication Critical patent/DE60225172D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M2005/1401—Functional features
    • A61M2005/1405—Patient controlled analgesia [PCA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1581—Right-angle needle-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0266—Shape memory materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/65—Impedance, e.g. conductivity, capacity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
DE60225172T 2001-10-26 2002-10-21 Transdermale transportvorrichtung mit mikronadeln Expired - Lifetime DE60225172D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33842501P 2001-10-26 2001-10-26
US39948902P 2002-07-29 2002-07-29
PCT/US2002/033794 WO2003037404A1 (en) 2001-10-26 2002-10-21 Microneedle transdermal transport device

Publications (1)

Publication Number Publication Date
DE60225172D1 true DE60225172D1 (de) 2008-04-03

Family

ID=26991185

Family Applications (3)

Application Number Title Priority Date Filing Date
DE60230896T Expired - Lifetime DE60230896D1 (en) 2001-10-26 2002-10-18 Mikronadeltransportvorrichtung
DE60225172T Expired - Lifetime DE60225172D1 (de) 2001-10-26 2002-10-21 Transdermale transportvorrichtung mit mikronadeln
DE60230795T Expired - Lifetime DE60230795D1 (de) 2001-10-26 2002-10-22 Transdermale transportvorrichtung mit ansaugung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60230896T Expired - Lifetime DE60230896D1 (en) 2001-10-26 2002-10-18 Mikronadeltransportvorrichtung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60230795T Expired - Lifetime DE60230795D1 (de) 2001-10-26 2002-10-22 Transdermale transportvorrichtung mit ansaugung

Country Status (8)

Country Link
US (7) US7429258B2 (de)
EP (5) EP1439871B1 (de)
JP (10) JP2005525141A (de)
AT (3) ATE420680T1 (de)
AU (3) AU2002353840B2 (de)
CA (5) CA2464483C (de)
DE (3) DE60230896D1 (de)
WO (5) WO2003037403A1 (de)

Families Citing this family (391)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6471635B1 (en) 2000-02-10 2002-10-29 Obtech Medical Ag Anal incontinence disease treatment with controlled wireless energy supply
US6464628B1 (en) 1999-08-12 2002-10-15 Obtech Medical Ag Mechanical anal incontinence
US6503189B1 (en) 1999-08-12 2003-01-07 Obtech Medical Ag Controlled anal incontinence disease treatment
US6482145B1 (en) 2000-02-14 2002-11-19 Obtech Medical Ag Hydraulic anal incontinence treatment
CN1202784C (zh) 2000-02-10 2005-05-25 波滕西亚医疗公司 控制小便失禁的治疗
DE60135257D1 (de) 2000-02-10 2008-09-18 Potencia Medical Ag Mechanische Vorrichtung zur Impotenzbehandlung
CA2398496C (en) 2000-02-10 2009-05-19 Surgical Development Ag Urinary incontinence treatment with wireless energy supply
CN1400888A (zh) 2000-02-11 2003-03-05 波滕西亚医疗公司 带能量变换装置的阳痿治疗设备
AU778406B2 (en) 2000-02-11 2004-12-02 Potentica Ag Controlled impotence treatment
WO2001047440A2 (en) 2000-02-14 2001-07-05 Potencia Medical Ag Male impotence prosthesis apparatus with wireless energy supply
US20030100929A1 (en) 2000-02-14 2003-05-29 Peter Forsell Controlled penile prosthesis
ATE296071T1 (de) 2000-02-14 2005-06-15 Potencia Medical Ag Penisprothese
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
DE60207902T2 (de) * 2001-01-30 2006-06-14 Nissan Chemical Ind Ltd Isocyanuratverbindung und Verfahren zu ihrer Herstellung
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US6966880B2 (en) * 2001-10-16 2005-11-22 Agilent Technologies, Inc. Universal diagnostic platform
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7858112B2 (en) * 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795334B2 (en) * 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US8784335B2 (en) * 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US20040039289A1 (en) * 2002-04-30 2004-02-26 Christensen Lars Hofmann Needle insertion sensor
CA2484265C (en) 2002-05-06 2012-08-07 Becton, Dickinson And Company Method and device for controlling drug pharmacokinetics
EP1389476A1 (de) * 2002-08-14 2004-02-18 Precimedix S.A. Programmiergerät für eine Medikamentinjektionpumpe
JP2005537054A (ja) * 2002-08-30 2005-12-08 ベクトン・ディキンソン・アンド・カンパニー 免疫調節化合物の薬物動態を制御する方法
US20120296233A9 (en) * 2002-09-05 2012-11-22 Freeman Dominique M Methods and apparatus for an analyte detecting device
US20040106894A1 (en) 2002-09-06 2004-06-03 Massachusetts Institute Of Technology Needleless drug injection device
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
KR20050105100A (ko) * 2003-03-06 2005-11-03 라이프스캔, 인코포레이티드 피부 조직 관통 시스템 및 방법
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
EP1644004A4 (de) 2003-06-20 2010-10-06 Ronald Aung-Din Topische therapie zur behandlung von migräne, muskelzerrungen, muskelspasmus, spastizität und verwandten zuständen
MXPA06001414A (es) * 2003-08-04 2006-08-25 Johnson & Johnson Metodo y dispositivo para incrementar el flujo de agente transdermico.
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
EP1527792A1 (de) 2003-10-27 2005-05-04 Novo Nordisk A/S Eine auf die Haut anbringbare medizinische Injektionsvorrichtung
EP1680154B1 (de) * 2003-10-31 2012-01-04 ALZA Corporation Selbstbetätigter applikator für eine mikroprojektionsanordnung
US7361182B2 (en) 2003-12-19 2008-04-22 Lightnix, Inc. Medical lancet
DK1706019T3 (da) * 2003-12-22 2009-02-02 Paul Hadvary Dermalt fastgjort sensorindretning
CA2552385C (en) * 2003-12-29 2013-07-23 3M Innovative Properties Company Medical devices and kits including same
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
EP3466483A1 (de) 2004-03-08 2019-04-10 Ichor Medical Systems Inc. Verbessertes gerät für die elektrisch vermittelte abgabe von therapeutika
WO2005110525A2 (en) * 2004-04-12 2005-11-24 Allergan, Inc. Multi-site injection system
WO2005118060A2 (en) * 2004-04-30 2005-12-15 Boston Scientific Limited Apparatus with partially insulated needle for measuring tissue impedance and method using same
EP1751546A2 (de) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Bedruckbares wassergel für biosensoren
US9775553B2 (en) * 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
WO2005120365A1 (en) * 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US7872396B2 (en) * 2004-06-14 2011-01-18 Massachusetts Institute Of Technology Electrochemical actuator
EP1784890A4 (de) 2004-06-14 2010-04-07 Massachusetts Inst Technology Elektrochemische verfahren, einrichtungen und strukturen
US8247946B2 (en) * 2004-06-14 2012-08-21 Massachusetts Institute Of Technology Electrochemical actuator
JP2008504895A (ja) * 2004-06-29 2008-02-21 スパイン・ウェイブ・インコーポレーテッド 椎間板の欠陥及び損傷を治療する方法
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
WO2006016364A2 (en) * 2004-08-10 2006-02-16 Hellman De Picciotto, Tania Drug delivery devices
WO2006018642A1 (en) 2004-08-16 2006-02-23 Functional Microstructures Limited Method of producing a microneedle or microimplant
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US7780981B2 (en) 2004-09-13 2010-08-24 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
WO2006055799A1 (en) * 2004-11-18 2006-05-26 3M Innovative Properties Company Masking method for coating a microneedle array
KR20070102669A (ko) * 2004-11-18 2007-10-19 쓰리엠 이노베이티브 프로퍼티즈 컴파니 로우-프로파일 미세 바늘 어레이 인가 장치
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
ATE504328T1 (de) 2004-11-18 2011-04-15 3M Innovative Properties Co Mikronadelanordungsapplikator und halter
US20080009801A1 (en) * 2004-12-02 2008-01-10 Nickel Janice H Method for dispensing material into a drug delivery device
CN100367906C (zh) * 2004-12-08 2008-02-13 圣美迪诺医疗科技(湖州)有限公司 皮下植入式生物传感器
US7833189B2 (en) * 2005-02-11 2010-11-16 Massachusetts Institute Of Technology Controlled needle-free transport
US7850645B2 (en) * 2005-02-11 2010-12-14 Boston Scientific Scimed, Inc. Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
EP1709989A1 (de) * 2005-04-04 2006-10-11 Christoph Burckhardt AG Tätowierpistolenspitze
JP5301985B2 (ja) * 2005-04-07 2013-09-25 スリーエム イノベイティブ プロパティズ カンパニー ツールフィードバック感知のためのシステム及び方法
EP1709906A1 (de) * 2005-04-07 2006-10-11 F. Hoffmann-La Roche Ag Verfahren und Vorrichtung zur Entnahme von Körperflüssigkeit
US8298172B2 (en) 2005-04-13 2012-10-30 Novo Nordisk A/S Medical skin mountable device and system
WO2006127905A2 (en) 2005-05-24 2006-11-30 Chrono Therapeutics, Inc. Portable drug delivery device
EP2921169A1 (de) * 2005-05-24 2015-09-23 Chrono Therapeutics, Inc. Tragbare Wirkstofffreisetzungsvorrichtung mit abnehmbarem und austauschbarem Verabreichungs- oder Dosierungselement
US20080269666A1 (en) * 2005-05-25 2008-10-30 Georgia Tech Research Corporation Microneedles and Methods for Microinfusion
EP1884259A4 (de) * 2005-05-27 2011-03-30 Olympus Corp Vorrichtung zur einführung in eine person
US8505544B2 (en) * 2005-05-31 2013-08-13 The Board Of Trustees Of The Leland Stanford Junior University Optically-implemented microsurgery system and approach
WO2006134153A1 (en) 2005-06-16 2006-12-21 Novo Nordisk A/S Method and apparatus for assisting patients in self administration of medication
EP1904158B1 (de) 2005-06-24 2013-07-24 3M Innovative Properties Company Faltbares Pflaster mit Mikronadelnanordnung
CA2613111C (en) * 2005-06-27 2015-05-26 3M Innovative Properties Company Microneedle array applicator device and method of array application
JP5006317B2 (ja) 2005-07-06 2012-08-22 バスキュラー・パスウェイズ・インコーポレイテッド 静脈カテーテル挿入装置及びその利用方法
US9687186B2 (en) 2005-07-21 2017-06-27 Steadymed Ltd. Drug delivery device
IL175460A (en) 2006-05-07 2011-05-31 Doron Aurbach Drug delivery device
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070066934A1 (en) * 2005-09-19 2007-03-22 Transport Pharmaceuticals, Inc. Electrokinetic delivery system and methods therefor
US8113244B2 (en) * 2006-02-09 2012-02-14 Deka Products Limited Partnership Adhesive and peripheral systems and methods for medical devices
JP4935286B2 (ja) * 2005-10-12 2012-05-23 パナソニック株式会社 血液センサ
CN101291697B (zh) 2005-10-17 2011-05-18 诺沃-诺迪斯克有限公司 有通气孔的药物贮存单元
EP2926847B1 (de) * 2005-11-02 2022-05-25 MedicalTree Patents Ltd. Implantierbare infusionsvorrichtung mit ausfahrbarer und einziehbarer nadel
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US9636035B2 (en) * 2005-12-14 2017-05-02 Scibase Ab Medical apparatus for determination of biological conditions using impedance measurements
JP4402648B2 (ja) * 2005-12-16 2010-01-20 オリンパス株式会社 被検体内導入装置
US7736310B2 (en) 2006-01-30 2010-06-15 Abbott Diabetes Care Inc. On-body medical device securement
EP1815790A1 (de) * 2006-02-04 2007-08-08 Roche Diagnostics GmbH Stechgerät mit Impedanzmesseinrichtung
US11318249B2 (en) 2006-02-09 2022-05-03 Deka Products Limited Partnership Infusion pump assembly
ATE532553T1 (de) * 2006-02-10 2011-11-15 Hisamitsu Pharmaceutical Co Transdermales arzneiverabreichungsgerät mit mikronadeln
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US7981034B2 (en) 2006-02-28 2011-07-19 Abbott Diabetes Care Inc. Smart messages and alerts for an infusion delivery and management system
WO2007106557A2 (en) 2006-03-14 2007-09-20 University Of Southern California Mems device for delivery of therapeutic agents
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
WO2007131050A2 (en) * 2006-05-02 2007-11-15 Georgia Tech Research Corporation Method for drug delivery to ocular tissue using microneedle
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US7621895B2 (en) * 2006-05-17 2009-11-24 Abbott Cardiovascular Systems Inc. Needle array devices and methods
US20070276318A1 (en) * 2006-05-26 2007-11-29 Mit, Llp Iontosonic-microneedle applicator apparatus and methods
US20090171269A1 (en) * 2006-06-29 2009-07-02 Abbott Diabetes Care, Inc. Infusion Device and Methods Therefor
US9119582B2 (en) * 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
JP2009545368A (ja) * 2006-08-01 2009-12-24 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 超音波で高められたマイクロ針
US8932216B2 (en) 2006-08-07 2015-01-13 Abbott Diabetes Care Inc. Method and system for providing data management in integrated analyte monitoring and infusion system
US8206296B2 (en) 2006-08-07 2012-06-26 Abbott Diabetes Care Inc. Method and system for providing integrated analyte monitoring and infusion system therapy management
WO2008027011A1 (en) * 2006-08-28 2008-03-06 Agency For Science, Technology And Research Microneedles and methods for fabricating microneedles
WO2008027218A2 (en) * 2006-08-29 2008-03-06 Alza Corporation Drug electrotransport with hydration measurement of hydratable reservoir
EP2063934A1 (de) * 2006-09-18 2009-06-03 Agency for Science, Technology and Research Nadelkonstruktionen und verfahren zur herstellung von nadelkonstruktionen
AU2007303821B9 (en) * 2006-10-05 2013-06-20 Technion Research & Development Foundation Ltd. Microtubes and methods of producing same
DK2084802T3 (da) * 2006-10-25 2019-05-13 Hoffmann La Roche Uafbrydelig strømforsyning til medicinsk apparat
US20080117416A1 (en) * 2006-10-27 2008-05-22 Hunter Ian W Use of coherent raman techniques for medical diagnostic and therapeutic purposes, and calibration techniques for same
US10525246B2 (en) * 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
US8845530B2 (en) * 2007-01-02 2014-09-30 Isense Corporation Resposable biosensor assembly and method of sensing
FR2912919B1 (fr) * 2007-02-22 2009-05-01 Bernard Perriere Dispositif d'injection miniaturise a usage medical
US20080249469A1 (en) * 2007-03-22 2008-10-09 Ponnambalam Selvaganapathy Method and apparatus for active control of drug delivery using electro-osmotic flow control
GB2448493B (en) * 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US8721546B2 (en) 2007-05-07 2014-05-13 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
WO2008154338A1 (en) * 2007-06-07 2008-12-18 Piezo Resonance Innovations, Inc. Eye surgical tool
CN101677988A (zh) * 2007-06-21 2010-03-24 藤本株式会社 经皮或经粘膜给药用组合物
US8641618B2 (en) 2007-06-27 2014-02-04 Abbott Diabetes Care Inc. Method and structure for securing a monitoring device element
US8085151B2 (en) 2007-06-28 2011-12-27 Abbott Diabetes Care Inc. Signal converting cradle for medical condition monitoring and management system
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
US9987468B2 (en) 2007-06-29 2018-06-05 Actuated Medical, Inc. Reduced force device for intravascular access and guidewire placement
US8043229B2 (en) * 2007-06-29 2011-10-25 Actuated Medical, Inc. Medical tool for reduced penetration force
US8328738B2 (en) 2007-06-29 2012-12-11 Actuated Medical, Inc. Medical tool for reduced penetration force with feedback means
US10219832B2 (en) 2007-06-29 2019-03-05 Actuated Medical, Inc. Device and method for less forceful tissue puncture
US7828771B2 (en) * 2007-07-26 2010-11-09 Entra Pharmaceuticals, Inc. Systems and methods for delivering drugs
CA2941187C (en) * 2007-08-14 2021-03-02 Fred Hutchinson Cancer Research Center Needle array assembly and method for delivering therapeutic agents
WO2009029572A1 (en) * 2007-08-24 2009-03-05 Deka Products Limited Partnership Microneedle systems and apparatus
WO2009029044A1 (en) * 2007-08-24 2009-03-05 Agency For Science, Technology And Research A system and method for detecting skin penetration
US9096845B2 (en) * 2007-08-29 2015-08-04 Technion Research & Development Foundation Limited Encapsulation of bacteria and viruses in electrospun fibers
US20090088682A1 (en) * 2007-09-28 2009-04-02 Seattle Medical Technologies Wearable infusion device
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
JP5461427B2 (ja) * 2007-12-17 2014-04-02 ニューワールド ファーマシューティカルズ，エルエルシー 統合的な皮内送達、診断、及び、情報伝達システム
EP2242464B2 (de) 2007-12-20 2017-03-01 University Of Southern California Vorrichtung zur abgabe von therapeutika
FI20075978A0 (fi) * 2007-12-31 2007-12-31 Katja Paassilta Järjestely ja menetelmä
BR122019016154B8 (pt) 2007-12-31 2021-06-22 Deka Products Lp conjunto de bomba de infusão
US11357910B2 (en) 2007-12-31 2022-06-14 Deka Products Limited Partnership Pump assembly with switch
WO2009088956A2 (en) 2007-12-31 2009-07-16 Deka Products Limited Partnership Infusion pump assembly
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
EP3964243A1 (de) 2008-01-28 2022-03-09 Implantica Patent Ltd Vorrichtung, system und verfahren zur entfernung eines blutgerinnsels
BRPI0906746A8 (pt) 2008-01-29 2019-05-14 Implantica Patent Ltd aparelho para tratamento de doença de refluxo gastresofágico
US9297094B2 (en) * 2008-02-21 2016-03-29 Technion Research & Development Foundation Ltd. Use of electrospun microtubes for drug delivery
US20090221893A1 (en) * 2008-02-29 2009-09-03 Path Scientific, Llc Unitized Painfree Blood Glucose Measuring Device
JP2009222474A (ja) * 2008-03-14 2009-10-01 Panasonic Corp 微量液体供給装置および微量液体供給方法
CN102202708B (zh) 2008-05-08 2015-01-21 迷你泵有限责任公司 药物输送泵及其制造方法
US9849238B2 (en) 2008-05-08 2017-12-26 Minipumps, Llc Drug-delivery pump with intelligent control
CA2723724C (en) 2008-05-08 2017-03-14 Replenish Pumps, Llc Implantable pumps and cannulas therefor
JP5584202B2 (ja) 2008-05-21 2014-09-03 セラジェクト， インコーポレイテッド 固溶体穿孔器パッチの製造方法及びその使用
US8591410B2 (en) 2008-05-30 2013-11-26 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
JP2011526889A (ja) 2008-06-30 2011-10-20 アフギン ファーマ，エルエルシー 局所局部的神経作用療法
JP4482617B2 (ja) * 2008-07-08 2010-06-16 パナソニック株式会社 導電性高分子を用いた流体搬送装置
US8868176B2 (en) * 2008-07-22 2014-10-21 New York University Microelectrode-equipped subdural therapeutic agent delivery strip
DK2626093T3 (en) * 2008-08-28 2014-02-24 Hoffmann La Roche DEVICE FOR INCREASING HYPODERMIC insulin absorption
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
US8650937B2 (en) 2008-09-19 2014-02-18 Tandem Diabetes Care, Inc. Solute concentration measurement device and related methods
US11123171B2 (en) 2008-10-10 2021-09-21 Peter Forsell Fastening means for implantable medical control assembly
ES2950024T3 (es) 2008-10-10 2023-10-04 Medicaltree Patent Ltd Dispositivo, sistema y procedimiento de ayuda al corazón
US9072907B2 (en) 2008-10-10 2015-07-07 Peter Forsell Heart help device, system, and method
EP2349170B1 (de) 2008-10-10 2023-09-27 Implantica Patent Ltd. Vorrichtung zur behandlung von weiblicher sexueller dysfunktion
US8874215B2 (en) 2008-10-10 2014-10-28 Peter Forsell System, an apparatus, and a method for treating a sexual dysfunctional female patient
EP2349096B1 (de) 2008-10-10 2021-01-27 MedicalTree Patent Ltd. Verbesserte künstliche herzklappe
WO2010052692A1 (en) * 2008-11-04 2010-05-14 Janisys Limited A transfer device for transferring a substance between the device and a subject
US20110301628A1 (en) * 2008-12-05 2011-12-08 Yossi Gross Techniques for use with a nail penetration device
US9358375B2 (en) 2008-12-19 2016-06-07 Janisys Limited Fluid transfer device and an active substance cartridge for the fluid transfer device, and a method for controlling the pressure at which an active substance is delivered to a subject from a fluid transfer device
US20100187132A1 (en) * 2008-12-29 2010-07-29 Don Alden Determination of the real electrochemical surface areas of screen printed electrodes
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
WO2012018486A2 (en) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US20110172510A1 (en) * 2010-01-13 2011-07-14 Seventh Sense Biosystems, Inc. Rapid delivery and/or withdrawal of fluids
US20110105951A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin
US8827971B2 (en) 2011-04-29 2014-09-09 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
WO2010101620A2 (en) * 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Systems and methods for creating and using suction blisters or other pooled regions of fluid within the skin
JP5563652B2 (ja) * 2009-03-17 2014-07-30 カーディオスライヴ インコーポレイテッド 体外除細動器
US8781576B2 (en) * 2009-03-17 2014-07-15 Cardiothrive, Inc. Device and method for reducing patient transthoracic impedance for the purpose of delivering a therapeutic current
DE102009002019A1 (de) 2009-03-31 2010-10-07 Robert Bosch Gmbh Applikator zur Behandlung von Haut
EP2424610A2 (de) * 2009-04-29 2012-03-07 Janisys Limited Mikronadelvorrichtung und gerät und verfahren zur applikation eines mikronadelelements auf eine stelle auf der haut einer person
WO2010127051A1 (en) 2009-04-29 2010-11-04 Abbott Diabetes Care Inc. Method and system for providing real time analyte sensor calibration with retrospective backfill
US20120197195A1 (en) * 2009-05-20 2012-08-02 Sanofi-Aventis Deutschland Gmbh Drug Delivery Device
US10952836B2 (en) 2009-07-17 2021-03-23 Peter Forsell Vaginal operation method for the treatment of urinary incontinence in women
US9949812B2 (en) 2009-07-17 2018-04-24 Peter Forsell Vaginal operation method for the treatment of anal incontinence in women
CA2769030C (en) 2009-07-30 2016-05-10 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
AU2010276511B2 (en) 2009-07-31 2013-09-19 Kindeva Drug Delivery L.P. Hollow microneedle arrays
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
KR101697388B1 (ko) 2009-08-18 2017-01-17 미니펌프스, 엘엘씨 적응 제어기를 갖춘 전해 약품 운반 펌프
US8758271B2 (en) 2009-09-01 2014-06-24 Massachusetts Institute Of Technology Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties
US20110060202A1 (en) * 2009-09-08 2011-03-10 Seth Adrian Miller Dehydration detector using micro-needles
JP5701882B2 (ja) * 2009-09-10 2015-04-15 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬剤容器
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
US20110143310A1 (en) * 2009-12-15 2011-06-16 Hunter Ian W Lorentz-Force Actuated Cleaning Device
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
CN102791197B (zh) * 2010-01-13 2016-03-23 第七感生物系统有限公司 取样装置接口
EP3243435A1 (de) * 2010-01-13 2017-11-15 Seventh Sense Biosystems, Inc. Schnittstellen für eine probenentnahmevorrichtung
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US8366667B2 (en) * 2010-02-11 2013-02-05 Baxter International Inc. Flow pulsatility dampening devices
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP2560703A2 (de) 2010-04-20 2013-02-27 MiniPumps, LLC Elektrolytisch angetriebene wirkstoffpumpenvorrichtungen
MX2012012567A (es) 2010-04-28 2012-11-21 Kimberly Clark Co Metodo para aumentar la permeabilidad de una barrera epitelial.
US9629979B2 (en) * 2010-04-28 2017-04-25 Sanovas, Inc. Pressure/Vacuum actuated catheter drug delivery probe
DK2563450T3 (da) 2010-04-28 2017-11-13 Kimberly Clark Co Apparat til administration af rheumatoid-arthritis-medikament
US9526883B2 (en) 2010-04-28 2016-12-27 Kimberly-Clark Worldwide, Inc. Composite microneedle array including nanostructures thereon
EP2563451B1 (de) 2010-04-28 2017-11-01 Kimberly-Clark Worldwide, Inc. Medizinische vorrichtungen zur abgabe von sirna
AU2011248108B2 (en) 2010-05-04 2016-05-26 Corium Pharma Solutions, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US8337457B2 (en) 2010-05-05 2012-12-25 Springleaf Therapeutics, Inc. Systems and methods for delivering a therapeutic agent
US9872971B2 (en) 2010-05-14 2018-01-23 C. R. Bard, Inc. Guidewire extension system for a catheter placement device
US10384039B2 (en) 2010-05-14 2019-08-20 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US9950139B2 (en) 2010-05-14 2018-04-24 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
US8932258B2 (en) 2010-05-14 2015-01-13 C. R. Bard, Inc. Catheter placement device and method
US11925779B2 (en) 2010-05-14 2024-03-12 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
WO2011156095A2 (en) 2010-06-10 2011-12-15 The Regents Of The University Of California Textile-based printable electrodes for electrochemical sensing
WO2011163347A2 (en) 2010-06-23 2011-12-29 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US9227021B2 (en) 2010-06-29 2016-01-05 Genesis Biosystems, Inc. Microneedle roller (MNR) infusion system
JP2013538069A (ja) 2010-07-16 2013-10-10 セブンス センス バイオシステムズ，インコーポレーテッド 流体移動デバイスのための低圧環境
US8814792B2 (en) 2010-07-27 2014-08-26 Carefusion 303, Inc. System and method for storing and forwarding data from a vital-signs monitor
US9017255B2 (en) 2010-07-27 2015-04-28 Carefusion 303, Inc. System and method for saving battery power in a patient monitoring system
US9615792B2 (en) 2010-07-27 2017-04-11 Carefusion 303, Inc. System and method for conserving battery power in a patient monitoring system
US9055925B2 (en) 2010-07-27 2015-06-16 Carefusion 303, Inc. System and method for reducing false alarms associated with vital-signs monitoring
US9357929B2 (en) 2010-07-27 2016-06-07 Carefusion 303, Inc. System and method for monitoring body temperature of a person
US9420952B2 (en) 2010-07-27 2016-08-23 Carefusion 303, Inc. Temperature probe suitable for axillary reading
US9585620B2 (en) 2010-07-27 2017-03-07 Carefusion 303, Inc. Vital-signs patch having a flexible attachment to electrodes
DE102010038733A1 (de) 2010-07-30 2012-02-02 Robert Bosch Gmbh Modulare Mikronadel-Transportvorrichtung
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US9173994B2 (en) * 2010-08-20 2015-11-03 Purdue Research Foundation Touch-actuated micropump for transdermal drug delivery and method of use
CA2812877C (en) 2010-09-27 2019-02-12 Steadymed, Ltd. Size-efficient drug-delivery device
CN107096101A (zh) 2010-10-07 2017-08-29 麻省理工学院 使用伺服控制的无针注射器的注射方法
US8821434B2 (en) 2010-10-07 2014-09-02 Massachusetts Institute Of Technology Delivery of a solid body and/or a fluid using a linear Lorentz-force actuated needle-free jet injection system
CN106214321B (zh) 2010-10-15 2018-08-28 科尼尔赛德生物医学公司 用于进入眼睛的装置
WO2012058192A1 (en) * 2010-10-26 2012-05-03 7944942 Canada Inc. Automatic medication injection device
US9017289B2 (en) 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
US8808202B2 (en) 2010-11-09 2014-08-19 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
CA2821979A1 (en) 2010-12-17 2012-06-21 Yet-Ming Chiang Electrochemical actuators
US8690833B2 (en) 2011-01-31 2014-04-08 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
US10130761B2 (en) 2011-02-09 2018-11-20 Becton, Dickinson And Company Infusion systems
EP3563898B1 (de) 2011-02-25 2020-11-11 C.R. Bard, Inc. Vorrichtung zum einsetzen medizinischer komponenten mit einer einziehbaren nadel
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
WO2012139593A2 (en) * 2011-04-15 2012-10-18 Rigshospitalet Copenhagen University Hospital System and method for injecting a substance into a human body
AU2012245372A1 (en) * 2011-04-19 2013-11-14 Invisiderm, Llc Method of producing substances with supersaturated gas,transdermal delivery device thereof, and uses thereof
BR112013027010A2 (pt) * 2011-04-19 2016-12-27 Invisiderm Llc método de produzir substâncias com gás supersaturado, dispositivo para sua entrega trasdérmica, e seus usos
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
WO2012149155A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
CA2833175A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Devices and methods for collection and/or manipulation of blood spots or other bodily fluids
USD903101S1 (en) 2011-05-13 2020-11-24 C. R. Bard, Inc. Catheter
US8636696B2 (en) * 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
KR101542549B1 (ko) 2011-09-02 2015-08-06 산디아 코포레이션 바이오센싱 및 약물 전달을 위한 마이크로니들 어레이
DK3542851T3 (da) 2011-10-27 2022-03-14 Sorrento Therapeutics Inc Implanterbare indretninger til levering af bioaktive midler
JP6100271B2 (ja) 2011-10-27 2017-03-22 キンバリー クラーク ワールドワイド インコーポレイテッド 高粘性生理活性薬剤の経皮的送達
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
CN104023760A (zh) 2011-10-28 2014-09-03 普莱萨格生命科学公司 药物递送方法
US9317656B2 (en) 2011-11-23 2016-04-19 Abbott Diabetes Care Inc. Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof
EP4144378A1 (de) 2011-12-16 2023-03-08 ModernaTX, Inc. Modifizierte nukleosid-, nukleotid- und nukleinsäurezusammensetzungen
DE102011089723A1 (de) * 2011-12-23 2013-06-27 Robert Bosch Gmbh Mikronadelarray-Applikator und Verfahren zur Applikation eines Mikronadelarrays
US10130800B2 (en) 2012-01-27 2018-11-20 Invisiderm, Llc Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof
WO2013136176A1 (en) * 2012-03-13 2013-09-19 Becton Dickinson France Injection device having a miniaturized drug delivery portion
ES2672239T3 (es) 2012-03-15 2018-06-13 Steadymed Ltd. Reducción mejorada del dolor en el lugar de infusión para dispositivos de administración de fármacos
US9724462B2 (en) 2012-03-19 2017-08-08 Steadymed Ltd. Fluid-connection mechanism for patch-pumps
KR20130114996A (ko) * 2012-04-10 2013-10-21 삼성디스플레이 주식회사 표시 장치 및 그 제조방법
CA3077452C (en) 2012-05-01 2022-08-09 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
EP2872222B1 (de) * 2012-07-06 2023-05-31 The General Hospital Corporation System und vorrichtung zur dermatologischen behandlung
US9782538B2 (en) 2012-09-27 2017-10-10 Becton, Dickinson And Company Angled inserter for drug infusion
MX2015005839A (es) 2012-11-08 2015-12-17 Clearside Biomedical Inc Metodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
SI2922554T1 (sl) 2012-11-26 2022-06-30 Modernatx, Inc. Terminalno modificirana RNA
MX2015008157A (es) 2012-12-21 2016-02-22 Corium Int Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
EP3434774A1 (de) 2013-01-17 2019-01-30 ModernaTX, Inc. Signal-sensor-polynukleotide zur veränderung zellulärer phänotypen
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
CN105102054B (zh) 2013-01-30 2018-04-20 血管通路股份有限公司 用于静脉穿刺和导管放置的系统和方法
BR112015020328B1 (pt) * 2013-02-28 2022-05-31 Sorrento Therapeutics, Inc Dispositivo de aplicação transdérmica de droga
EP4094799A1 (de) 2013-03-12 2022-11-30 Corium, Inc. Mikroprojektionsapplikatoren
WO2014159813A1 (en) 2013-03-13 2014-10-02 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
JP6098250B2 (ja) * 2013-03-14 2017-03-22 セイコーエプソン株式会社 液体輸送装置
US10080839B2 (en) 2013-03-14 2018-09-25 Becton, Dickinson And Company Angled inserter for drug infusion
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
JP2016514133A (ja) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法
WO2014143770A1 (en) * 2013-03-15 2014-09-18 Amgen Inc. Body contour adaptable autoinjector device
RU2711567C2 (ru) 2013-03-15 2020-01-17 Кориум, ИНК. Микрочип для доставки лекарственного средства и способы его использования
US9821113B2 (en) 2013-03-15 2017-11-21 Becton, Dickinson And Company Automatic angled infusion set assembly
US9603995B2 (en) 2013-03-15 2017-03-28 Tandem Diabetes Care. Inc. Device and method for setting therapeutic parameters for an infusion device
US10195409B2 (en) * 2013-03-15 2019-02-05 Corium International, Inc. Multiple impact microprojection applicators and methods of use
CN105246529B (zh) 2013-05-03 2019-06-14 科尼尔赛德生物医学公司 用于眼部注射的设备和方法
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US10188550B2 (en) 2013-06-03 2019-01-29 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
US9616243B2 (en) 2013-06-14 2017-04-11 Cardiothrive, Inc. Dynamically adjustable multiphasic defibrillator pulse system and method
US9656094B2 (en) 2013-06-14 2017-05-23 Cardiothrive, Inc. Biphasic or multiphasic pulse generator and method
US10149973B2 (en) 2013-06-14 2018-12-11 Cardiothrive, Inc. Multipart non-uniform patient contact interface and method of use
US10279189B2 (en) 2013-06-14 2019-05-07 Cardiothrive, Inc. Wearable multiphasic cardioverter defibrillator system and method
US9833630B2 (en) 2013-06-14 2017-12-05 Cardiothrive, Inc. Biphasic or multiphasic pulse waveform and method
US9907970B2 (en) 2013-06-14 2018-03-06 Cardiothrive, Inc. Therapeutic system and method using biphasic or multiphasic pulse waveform
KR101751653B1 (ko) 2013-06-18 2017-06-27 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
ES2753423T3 (es) 2013-06-19 2020-04-08 Hisamitsu Pharmaceutical Co Aplicador
US20150027241A1 (en) * 2013-07-23 2015-01-29 Diba Industries, Inc. Piercing probes with offset conical piercing tip and fluid-sampling systems comprising the piercing probes
US10299793B2 (en) 2013-10-23 2019-05-28 Valtech Cardio, Ltd. Anchor magazine
US20160367638A1 (en) 2013-12-19 2016-12-22 Crystal BYERS LEPTIN mRNA COMPOSITIONS AND FORMULATIONS
WO2015119906A1 (en) 2014-02-05 2015-08-13 Amgen Inc. Drug delivery system with electromagnetic field generator
GB201403773D0 (en) * 2014-03-04 2014-04-16 Univ Cardiff Microneedle based cell delivery
US10279106B1 (en) 2014-05-08 2019-05-07 Tandem Diabetes Care, Inc. Insulin patch pump
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
JP6822843B2 (ja) 2014-06-03 2021-01-27 アムジエン・インコーポレーテツド 薬物送達装置によって収集されたデータを遠隔で処理するためのシステム及び方法
WO2015196085A2 (en) 2014-06-20 2015-12-23 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
US10321858B2 (en) 2014-08-18 2019-06-18 Proteadx, Inc. Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
US10232146B2 (en) 2014-09-05 2019-03-19 C. R. Bard, Inc. Catheter insertion device including retractable needle
JP2017527394A (ja) * 2014-09-15 2017-09-21 サノフイ ベース上に回転可能なハウジングを有する薬剤送達デバイス
DE102014219719B4 (de) * 2014-09-29 2018-05-03 Ipr Intelligente Peripherien Für Roboter Gmbh Nadelgreifer
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
USD750223S1 (en) 2014-10-14 2016-02-23 Clearside Biomedical, Inc. Medical injector for ocular injection
JP6214786B2 (ja) * 2014-10-27 2017-10-18 深▲せん▼市光聚通訊技術開発有限公司Ｓｈｅｎｚｈｅｎ Ｗａｖｅｇｕｉｄｅｒ Ｏｐｔｉｃａｌ Ｔｅｌｅｃｏｍ Ｔｅｃｈｎｏｌｏｇｙ Ｉｎｃ． 持続血糖採取装置及び本体
WO2016100055A1 (en) 2014-12-19 2016-06-23 Amgen Inc. Drug delivery device with live button or user interface field
JP6716566B2 (ja) 2014-12-19 2020-07-01 アムジエン・インコーポレーテツド 近接センサ付き薬物送達装置
AU2015371287A1 (en) 2014-12-23 2017-06-08 Axell Wireless Ltd. Harmonizing noise aggregation and noise management in distributed antenna system
EP3045185A1 (de) * 2015-01-16 2016-07-20 Sanofi-Aventis Deutschland GmbH Konnektor für einen mit einem flüssigen arzneimittel gefüllten behälter
US10213586B2 (en) 2015-01-28 2019-02-26 Chrono Therapeutics Inc. Drug delivery methods and systems
EP3258988B1 (de) * 2015-02-17 2019-08-28 Amgen Inc. Arzneimittelabgabevorrichtung mit vakuumunterstützter sicherung und/oder rückkopplung
US10433928B2 (en) 2015-03-10 2019-10-08 Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company Multiple needle injector
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
USD903100S1 (en) 2015-05-01 2020-11-24 C. R. Bard, Inc. Catheter placement device
JP6784352B2 (ja) * 2015-05-11 2020-11-11 国立大学法人 東京医科歯科大学 インスリン送達用デバイス
CA2985202C (en) 2015-05-15 2023-10-10 C.R. Bard, Inc. Catheter placement device including an extensible needle safety component
US10463847B2 (en) 2015-06-11 2019-11-05 Steadymed Ltd. Infusion set
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10940292B2 (en) 2015-07-08 2021-03-09 Actuated Medical, Inc. Reduced force device for intravascular access and guidewire placement
US11793543B2 (en) 2015-09-18 2023-10-24 Obvius Robotics, Inc. Device and method for automated insertion of penetrating member
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
EP3413851B1 (de) 2016-02-10 2023-09-27 Clearside Biomedical, Inc. Verpackung
WO2017143153A1 (en) * 2016-02-19 2017-08-24 North Carolina State University Methods and compositions related to physiologically responsive microneedle delivery systems
AU2017241925B2 (en) 2016-03-28 2022-01-13 Ichor Medical Systems, Inc. Method and apparatus for delivery of therapeutic agents
KR102288170B1 (ko) 2016-04-08 2021-08-09 알레간 인코포레이티드 흡인 및 주입 디바이스
JP2019514581A (ja) 2016-05-02 2019-06-06 クリアサイド バイオメディカル，インコーポレイテッド 眼の薬物送達のためのシステムおよび方法
NL2016807B1 (en) * 2016-05-20 2017-11-27 Uprax System and method for applying microneedles
WO2017198872A1 (en) * 2016-05-20 2017-11-23 Uprax System and method for applying microneedles
US10220195B2 (en) * 2016-06-08 2019-03-05 Eclipse Medcorp, Llc Radio frequency needling device for use with disposable needle cartridges
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
SG11201901968TA (en) 2016-09-12 2019-04-29 Bard Inc C R Blood control for a catheter insertion device
US11241563B2 (en) 2016-12-22 2022-02-08 Johnson & Johnson Consumer Inc. Microneedle arrays and methods for making and using
EP3338832A1 (de) * 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Medikamentenverabreichungsvorrichtung
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 経皮薬剤送達の装置及び方法
US11400260B2 (en) 2017-03-01 2022-08-02 C. R. Bard, Inc. Catheter insertion device
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
CN109833562B (zh) * 2017-11-27 2024-03-15 苏州纳通生物纳米技术有限公司 一种一次性自毁式振动头组件以及应用该组件的促渗仪
US10828500B2 (en) 2017-12-22 2020-11-10 Cardiothrive, Inc. External defibrillator
IL275855B2 (en) * 2018-01-07 2023-11-01 Avraham Amir Needles with high carrying capacity and compounds to improve skin appearance
US11389626B2 (en) 2018-03-07 2022-07-19 Bard Access Systems, Inc. Guidewire advancement and blood flashback systems for a medical device insertion system
US11090506B2 (en) * 2018-05-15 2021-08-17 Omm Imports, Inc. Disposable product cap and assembly having a manually usable thermo-optical device for skin care
CA3101966A1 (en) 2018-05-29 2019-12-05 Morningside Venture Investments Limited Drug delivery methods and systems
US11464955B2 (en) * 2018-06-29 2022-10-11 Johnson & Johnson Consumer Inc. Three-dimensional microfluidics devices for the delivery of actives
USD921884S1 (en) 2018-07-27 2021-06-08 Bard Access Systems, Inc. Catheter insertion device
FR3084578B1 (fr) * 2018-08-03 2024-01-12 Pkvitality Gestion enfoncement de microaiguilles
US11446434B2 (en) 2019-02-22 2022-09-20 Deka Products Limited Partnership Infusion set and inserter assembly systems and methods
WO2020188484A1 (en) * 2019-03-19 2020-09-24 King Abdullah University Of Science And Technology Miniaturized delivery system and method
US11590332B2 (en) * 2019-04-17 2023-02-28 Path Scientific, Llc Precision microneedling device and methods of use
GB201908043D0 (en) * 2019-06-05 2019-07-17 Lekkos Vasileios Transdermal patch for therapeutic uses
KR102279603B1 (ko) * 2019-06-11 2021-07-20 (주)비올 바늘 조립체, 이를 포함하는 피부 자극기 및 그 제조 방법
EP3997452A4 (de) 2019-07-12 2023-08-16 Qulab Medical Ltd. Elektrochemischer fet-sensor
WO2021020730A2 (ko) * 2019-07-26 2021-02-04 주식회사 림사이언스 의료용 니들을 가압하는 장치
CN112386778A (zh) 2019-08-19 2021-02-23 贝克顿·迪金森公司 中线导管放置装置
US20220379022A1 (en) * 2019-10-30 2022-12-01 Thermalin, Inc. Agent delivery systems, devices, and methods
CN115087480A (zh) * 2020-02-20 2022-09-20 朱比利生物科技有限公司 用于给药的涂药器和用于其的微针贴片
WO2022026764A1 (en) 2020-07-29 2022-02-03 Biolinq Inc. Continuous analyte monitoring system with microneedle array
CN112370653B (zh) * 2020-11-12 2022-08-30 深圳市圣通生物科技有限公司 一种喷淋消毒式纳米微针中胚层导入美容仪
US20220273352A1 (en) * 2021-03-01 2022-09-01 Bluexthermal, Inc. Device and method for thermal modulation of tissue
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
SE545874C2 (en) 2021-05-08 2024-02-27 Biolinq Incorporated Fault detection for microneedle array based continuous analyte monitoring device
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11510602B1 (en) 2021-11-08 2022-11-29 Satio, Inc. Dermal patch for collecting a physiological sample
EP4295873A1 (de) * 2022-06-21 2023-12-27 National University of Ireland Galway Infusionskathetersystem

Family Cites Families (144)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US447225A (en) * 1891-02-24 Machine for attaching stays to the corners of boxes
US3537A (en) 1844-04-13 X g gupping instrument
US3659A (en) * 1844-07-11 Machine for hulling and pearling rice
US1934043A (en) 1929-05-17 1933-11-07 Standard Oil Dev Co Process of improvement of lubricating oils
DE596981C (de) 1931-10-30 1934-05-12 Mario Demarchi Dr Injektionsspritze
FR757501A (fr) 1932-09-23 1933-12-28 Dispositif automatique pour la manceuvre des seringues d'injection
US2088780A (en) 1936-10-09 1937-08-03 Sigurd E Follese Massage device
US2763935A (en) 1954-06-11 1956-09-25 Purdne Res Foundation Determining depth of layers of fat and of muscle on an animal body
US2945496A (en) 1958-08-18 1960-07-19 Fosdal Alfred Dental instrument for immobilizing tissue
DE1115722B (de) 1960-04-30 1961-10-26 Hoechst Ag Metallanode fuer die elektrolytische Abscheidung von Chlor
GB1128329A (en) 1964-12-23 1968-09-25 Nat Res Dev Electrodes for making electrical contact to the living body of a mammal
US3568735A (en) * 1968-06-26 1971-03-09 Cooke Eng Co Laboratory microtitration dispensing apparatus
US3568732A (en) 1969-02-28 1971-03-09 Kelly James A Jun Splice straightener for aerial conductors
US3659600A (en) 1970-02-24 1972-05-02 Estin Hans H Magnetically operated capsule for administering drugs
US3727614A (en) 1971-05-13 1973-04-17 Merck & Co Inc Multiple dosage inoculator
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3738493A (en) 1971-09-24 1973-06-12 Analytical Instr Spec Apparatus for simultaneous application of samples to thin layer chromatography plates
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
CH557178A (de) 1972-08-10 1974-12-31 Siemens Ag Geraet fuer die zufuehrung von medikamenten.
US3923060A (en) 1974-04-23 1975-12-02 Jr Everett H Ellinwood Apparatus and method for implanted self-powered medication dispensing having timing and evaluator means
US4140109A (en) 1977-10-17 1979-02-20 Savic Michael I Impedance-based method and apparatus for monitoring cryodestruction in controlled cryosurgery
FR2460343A1 (fr) 1979-06-29 1981-01-23 Solvay Cathode pour la production electrolytique d'hydrogene
JPS5683360A (en) * 1979-12-10 1981-07-07 Olympus Optical Co Pneumoperitoneum needle
US4447225A (en) 1982-03-22 1984-05-08 Taff Barry E Multidose jet injector
US4619652A (en) 1982-12-23 1986-10-28 Alza Corporation Dosage form for use in a body mounted pump
US4505710A (en) 1983-05-13 1985-03-19 Collins Earl R Implantable fluid dispensing system
DE3502913C1 (de) 1985-01-29 1986-07-03 Günter Prof. Dr.rer.nat. 5100 Aachen Rau Messaufnehmer zur nichtinvasiven Erfassung elektrophysiologischer Groessen
US4777599A (en) 1985-02-26 1988-10-11 Gillette Company Viscoelastometry of skin using shear wave propagation
FR2594341B1 (fr) * 1986-02-14 1990-08-10 Charton Jean Pierre Appareil injecteur pour la pratique de la mesotherapie
AT384737B (de) 1986-04-04 1987-12-28 Thoma Dipl Ing Dr Techn Herwig Vorrichtung zur stroemungskonstanten abgabe fluessiger arzneimittel
DE3789477T2 (de) * 1986-09-18 1994-07-14 Paul G Yock Vorrichtung für Anwendung in der Kanalisation von Blutgefässen.
US4886499A (en) 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
US4808156A (en) 1987-03-09 1989-02-28 Dean Consuelo M Cannular instrument and method for inserting a cannular instrument into a vein
US6056716A (en) 1987-06-08 2000-05-02 D'antonio Consultants International Inc. Hypodermic fluid dispenser
DD262803A1 (de) 1987-08-05 1988-12-14 Transform Roentgen Matern Veb Injektionseinrichtung
US5312486A (en) 1987-12-24 1994-05-17 Frank Meyer Water-containing, hardenable foam compositions with inorganic components and process for their preparation
US4989614A (en) 1988-02-23 1991-02-05 Vance Products Incorporated Fine-needle aspiration cell sampling methods
CA2008262A1 (en) * 1989-01-30 1990-07-30 John A. Gilly Clinical applicator
US5425706A (en) 1989-02-24 1995-06-20 S. I. Scientific Innovations Ltd. Dispensing device particularly useful for dispensing nutritional liquids
US5062834A (en) 1989-02-24 1991-11-05 Product Development (S.G.Z.) Ltd Device for dispensing a liquid particularly useful for delivering medicaments at a predetermined rate
JPH0648975B2 (ja) 1989-10-02 1994-06-29 俊郎 樋口 微小インジェクション装置及びそのインジェクション制御方法
US5262128A (en) 1989-10-23 1993-11-16 The United States Of America As Represented By The Department Of Health And Human Services Array-type multiple cell injector
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5697901A (en) 1989-12-14 1997-12-16 Elof Eriksson Gene delivery by microneedle injection
US6090790A (en) 1989-12-14 2000-07-18 Eriksson; Elof Gene delivery by microneedle injection
US5092901A (en) 1990-06-06 1992-03-03 The Royal Institution For The Advancement Of Learning (Mcgill University) Shape memory alloy fibers having rapid twitch response
TW279133B (de) 1990-12-13 1996-06-21 Elan Med Tech
US5156591A (en) 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
US5279547A (en) 1991-01-03 1994-01-18 Alcon Surgical Inc. Computer controlled smart phacoemulsification method and apparatus
SE9101022D0 (sv) * 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US5312456A (en) 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
US5533995A (en) 1991-11-13 1996-07-09 Elan Corporation, Plc Passive transdermal device with controlled drug delivery
US6048337A (en) 1992-01-07 2000-04-11 Principal Ab Transdermal perfusion of fluids
KR0145453B1 (ko) 1992-01-21 1998-07-01 알렌 제이 전기외과용 투관침 제어장치
US5252023A (en) * 1992-02-10 1993-10-12 Kelly Kevin M Lifting apparatus
JP2572823Y2 (ja) 1992-02-13 1998-05-25 株式会社アドバンス 簡易採血器
WO1993020784A1 (en) 1992-04-10 1993-10-28 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University A microneedle for injection of ocular blood vessels
US5478328A (en) 1992-05-22 1995-12-26 Silverman; David G. Methods of minimizing disease transmission by used hypodermic needles, and hypodermic needles adapted for carrying out the method
JPH0698920A (ja) * 1992-09-21 1994-04-12 Hayashi Shigetada 鍼灸精密測定器
US5354273A (en) 1992-12-14 1994-10-11 Mallinckrodt Medical, Inc. Delivery apparatus with pressure controlled delivery
US5478323A (en) * 1993-04-02 1995-12-26 Eli Lilly And Company Manifold for injection apparatus
IE68890B1 (en) 1993-04-08 1996-07-24 Elan Med Tech Intradermal delivery device
US5335668A (en) * 1993-04-30 1994-08-09 Medical Scientific, Inc. Diagnostic impedance measuring system for an insufflation needle
JP3494183B2 (ja) * 1993-08-10 2004-02-03 株式会社アドバンス 簡易採血装置
CA2171563A1 (en) 1993-09-14 1995-03-23 Eric Le Cheminant Injection device
US5389222A (en) 1993-09-21 1995-02-14 The United States Of America As Represented By The United States Department Of Energy Spring-loaded polymeric gel actuators
US5599346A (en) 1993-11-08 1997-02-04 Zomed International, Inc. RF treatment system
US5997501A (en) 1993-11-18 1999-12-07 Elan Corporation, Plc Intradermal drug delivery device
US5611806A (en) 1994-05-23 1997-03-18 Samsung Electro-Mechanics Co., Ltd. Skin perforating device for transdermal medication
CA2149836C (en) 1994-05-23 1999-07-06 Sang Bae Choi Perforating device for dermal administration
US5591139A (en) 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
US5649423A (en) 1994-06-07 1997-07-22 Sandia Corporation Micromechanism linear actuator with capillary force sealing
DE4420232A1 (de) 1994-06-07 1995-12-14 Robert Waltereit Vorrichtung zur Prüfung der Eindringtiefe einer Kanüle oder Sonde in den Körper eines Patienten
US5478315A (en) 1994-08-08 1995-12-26 Brothers Family Investments, L.C. Local anesthetic injection system
US5432098A (en) 1994-10-31 1995-07-11 Dynatech Precision Sampling Corporation Apparatus, and process, for automatically sampling solids and semi-solids materials for analysis
IE72524B1 (en) * 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
GB9508606D0 (en) 1995-04-27 1995-06-14 Svedman Paul Suction blister sampling
WO1996037256A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
US5827216A (en) * 1995-06-07 1998-10-27 Cormedics Corp. Method and apparatus for accessing the pericardial space
US5858001A (en) * 1995-12-11 1999-01-12 Elan Medical Technologies Limited Cartridge-based drug delivery device
JPH09192218A (ja) * 1996-01-16 1997-07-29 Hitachi Ltd 血糖値管理システム
JPH09239031A (ja) * 1996-03-09 1997-09-16 Honda Electron Co Ltd 超音波振動子を装着した注射器
US5843016A (en) 1996-03-18 1998-12-01 Physion S.R.L. Electromotive drug administration for treatment of acute urinary outflow obstruction
US6117155A (en) 1996-05-01 2000-09-12 Lee; Young H. Coated needle for use with an intramuscular stimulation treatment device
US5785688A (en) 1996-05-07 1998-07-28 Ceramatec, Inc. Fluid delivery apparatus and method
US5954668A (en) 1996-06-14 1999-09-21 Medrad, Inc. Extravasation detector using microwave radiometry
ATE234129T1 (de) 1996-06-18 2003-03-15 Alza Corp Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
US6183434B1 (en) 1996-07-03 2001-02-06 Spectrx, Inc. Multiple mechanical microporation of skin or mucosa
JPH1043296A (ja) * 1996-08-05 1998-02-17 Terumo Corp 薬液注入器具
ATE231015T1 (de) 1996-09-17 2003-02-15 Deka Products Lp System zur medikamentenabgabe durch transport
US6071251A (en) 1996-12-06 2000-06-06 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
SE9604564D0 (sv) 1996-12-12 1996-12-12 Paal Svedman Sätt och anordning vid avledning av elektriska strömmar
US6246904B1 (en) 1996-12-17 2001-06-12 Alza Corporation Electrotransport drug delivery reservoirs containing inert fillers
US5928194A (en) 1997-04-07 1999-07-27 Maget; Henri J. R. Self-contained liquid microdispenser
US5928207A (en) 1997-06-30 1999-07-27 The Regents Of The University Of California Microneedle with isotropically etched tip, and method of fabricating such a device
US5972013A (en) 1997-09-19 1999-10-26 Comedicus Incorporated Direct pericardial access device with deflecting mechanism and method
JPH11137684A (ja) * 1997-11-12 1999-05-25 Hiroshi Oya 無痛安全注射器
EP1032441B1 (de) * 1997-11-26 2004-03-03 E-Z-Em, Inc. Extravasationserkennungsvorrichtung
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
ATE221400T1 (de) 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
DK1037686T3 (da) 1997-12-11 2006-01-02 Alza Corp Apparat til forögelse af transdermal gennemströmning af midler
US6126629A (en) 1997-12-18 2000-10-03 Bausch & Lomb Surgical, Inc. Multiple port phaco needle
US6154673A (en) * 1997-12-30 2000-11-28 Agilent Technologies, Inc. Multilingual defibrillator
US6048204A (en) * 1998-02-03 2000-04-11 Lifecore Biomedical, Inc. Self tapping screw type dental implant
US5957895A (en) 1998-02-20 1999-09-28 Becton Dickinson And Company Low-profile automatic injection device with self-emptying reservoir
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US5971998A (en) 1998-03-31 1999-10-26 Donald G. Russell Support device and method for controlling breast thickness during stereotactic guided needle biopsy
WO1999058050A1 (en) 1998-05-13 1999-11-18 Cygnus, Inc. Signal processing for measurement of physiological analytes
DK1077634T3 (da) 1998-05-13 2003-11-24 Cygnus Therapeutic Systems Monitorering af fysiologiske analytter
EP1082151A1 (de) 1998-06-04 2001-03-14 ELAN CORPORATION, Plc Gasbetriebene medikamentenabgabevorrichtung
AU767122B2 (en) 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6678556B1 (en) 1998-07-13 2004-01-13 Genetronics, Inc. Electrical field therapy with reduced histopathological change in muscle
GB9815819D0 (en) 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
GB9815820D0 (en) 1998-07-22 1998-09-16 Secr Defence Improvements relating to micro-machining
WO2000006227A1 (en) 1998-07-27 2000-02-10 Medi-Ject Corporation Loading mechanism for medical injector assembly
JP2002526273A (ja) 1998-09-18 2002-08-20 ザ ユニヴァーシティ オブ ユタ リサーチ ファウンデーション 表面マイクロマシニングしたマイクロニードル
DE19843733A1 (de) * 1998-09-24 2000-03-30 Voith Sulzer Papiertech Patent Rakelvorrichtung
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6317630B1 (en) 1999-01-29 2001-11-13 Yossi Gross Drug delivery device
US6132449A (en) 1999-03-08 2000-10-17 Agilent Technologies, Inc. Extraction and transportation of blood for analysis
US6319230B1 (en) 1999-05-07 2001-11-20 Scimed Life Systems, Inc. Lateral needle injection apparatus and method
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
DE60044084D1 (de) 1999-06-04 2010-05-12 Georgia Tech Res Inst Vorrichtungen zur vergrösserten penetration von mikronadeln in biologischen hautschichten
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6607495B1 (en) * 1999-06-18 2003-08-19 University Of Virginia Patent Foundation Apparatus for fluid transport and related method thereof
US6408204B1 (en) 1999-07-28 2002-06-18 Medrad, Inc. Apparatuses and methods for extravasation detection
DE60022540T2 (de) * 1999-11-15 2006-06-14 Velcro Ind Befestigungselement für die haut
EP1239775B1 (de) * 1999-12-16 2005-03-16 ALZA Corporation Vorrichtung zur erhöhung des transdermalen flusses von probenwirkstoffen
US7003336B2 (en) * 2000-02-10 2006-02-21 Medtronic Minimed, Inc. Analyte sensor method of making the same
US6572740B2 (en) 2000-04-13 2003-06-03 Elan Pharma International Limited Electrolytic cell
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6440096B1 (en) * 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
JP2002028247A (ja) * 2000-07-18 2002-01-29 Japan Science & Technology Corp 穿刺針による静脈刺入の感知方法及び装置
EP2578252B1 (de) 2000-11-30 2019-01-09 Valeritas, Inc. Vorrichtung mit im wesentlichen frei beweglicher Mikrosonde über dem Gehäuse
EP1395320B1 (de) 2001-06-11 2006-06-28 Glaxo Group Limited Medikamentenspender
US6835193B2 (en) 2001-07-10 2004-12-28 Myocardial Therapeutics, Inc. Methods for controlled depth injections into interior body cavities
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7364586B2 (en) * 2001-12-21 2008-04-29 The Trustees Of Columbia University In The City Of New York C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis
EP1403519A1 (de) * 2002-09-27 2004-03-31 Novo Nordisk A/S Membranpumpe mit dehnbarer Pumpenmembran

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US20030083618A1 (en) 2003-05-01
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US7651475B2 (en) 2010-01-26
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