DE60231436D1 - Kodierte, selbst-assemblierende chemische bibliotheken (esachel) - Google Patents
Kodierte, selbst-assemblierende chemische bibliotheken (esachel)Info
- Publication number
- DE60231436D1 DE60231436D1 DE60231436T DE60231436T DE60231436D1 DE 60231436 D1 DE60231436 D1 DE 60231436D1 DE 60231436 T DE60231436 T DE 60231436T DE 60231436 T DE60231436 T DE 60231436T DE 60231436 D1 DE60231436 D1 DE 60231436D1
- Authority
- DE
- Germany
- Prior art keywords
- self
- moiety
- chemical
- assembly
- chemical compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1062—Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/08—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
- C40B50/10—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support involving encoding steps
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/101—Interaction between at least two labels
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Structural Engineering (AREA)
- Gastroenterology & Hepatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Dental Preparations (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36259902P | 2002-03-08 | 2002-03-08 | |
PCT/EP2002/004153 WO2003076943A1 (en) | 2002-03-08 | 2002-04-15 | Encoded self-assembling chemical libraries (esachel) |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60231436D1 true DE60231436D1 (de) | 2009-04-16 |
Family
ID=27805199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60231436T Expired - Lifetime DE60231436D1 (de) | 2002-03-08 | 2002-04-15 | Kodierte, selbst-assemblierende chemische bibliotheken (esachel) |
Country Status (12)
Country | Link |
---|---|
US (6) | US20060154246A1 (de) |
EP (1) | EP1483585B1 (de) |
KR (1) | KR100916889B1 (de) |
AT (1) | ATE424561T1 (de) |
AU (1) | AU2002310846B2 (de) |
CA (1) | CA2478203C (de) |
DE (1) | DE60231436D1 (de) |
DK (1) | DK1483585T3 (de) |
EA (1) | EA006965B1 (de) |
ES (1) | ES2321067T3 (de) |
HK (1) | HK1070427A1 (de) |
WO (1) | WO2003076943A1 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6407816B1 (en) * | 1998-02-23 | 2002-06-18 | Zygo Corporation | Interferometer and method for measuring the refractive index and optical path length effects of air |
WO2002074929A2 (en) * | 2001-03-19 | 2002-09-26 | President And Fellows Of Harvard College | Evolving new molecular function |
WO2002102820A1 (en) | 2001-06-20 | 2002-12-27 | Nuevolution A/S | Nucleoside derivatives for library preparation |
DE60231436D1 (de) | 2002-03-08 | 2009-04-16 | Eidgenoess Tech Hochschule | Kodierte, selbst-assemblierende chemische bibliotheken (esachel) |
US7413854B2 (en) | 2002-03-15 | 2008-08-19 | Nuevolution A/S | Method for synthesising templated molecules |
US10730906B2 (en) | 2002-08-01 | 2020-08-04 | Nuevolutions A/S | Multi-step synthesis of templated molecules |
JP4657919B2 (ja) * | 2002-08-19 | 2011-03-23 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 進化する新しい分子機能 |
EP3299463B1 (de) | 2002-10-30 | 2020-10-21 | Nuevolution A/S | Enzymatisches codieren |
WO2004056994A2 (en) | 2002-12-19 | 2004-07-08 | Nuevolution A/S | Quasirandom structure and function guided synthesis methods |
WO2004074429A2 (en) | 2003-02-21 | 2004-09-02 | Nuevolution A/S | Method for producing second-generation library |
US8017323B2 (en) * | 2003-03-26 | 2011-09-13 | President And Fellows Of Harvard College | Free reactant use in nucleic acid-templated synthesis |
WO2005026387A1 (en) | 2003-09-18 | 2005-03-24 | Nuevolution A/S | A method for obtaining structural information concerning an encoded molecule and method for selecting compounds |
US7972994B2 (en) | 2003-12-17 | 2011-07-05 | Glaxosmithkline Llc | Methods for synthesis of encoded libraries |
NZ547723A (en) * | 2003-12-17 | 2009-09-25 | Praecis Pharm Inc | Methods for synthesis of encoded libraries |
US20050153321A1 (en) * | 2003-12-30 | 2005-07-14 | Saba James A. | Libraries of multiple-ligand-conjugated nucleic acids |
EP1718765A2 (de) * | 2004-01-26 | 2006-11-08 | Isis Innovation Limited | Molekularanalyse |
EP1842226B2 (de) * | 2004-11-03 | 2014-07-02 | Iris International, Inc. | Homogener nachweis von analyten |
ATE530666T1 (de) | 2004-11-03 | 2011-11-15 | Iris Molecular Diagnostics Inc | Mikrobläschen zur affinitätstrennung |
LT3305900T (lt) | 2005-12-01 | 2021-11-10 | Nuevolution A/S | Fermentiniai kodavimo būdai didelių bibliotekų efektyviai sintezei |
EP2064348B1 (de) | 2006-09-18 | 2012-02-08 | Ensemble Therapeutics Corporation | Profilierung einer rezeptorfamilie |
KR20170119729A (ko) | 2009-02-13 | 2017-10-27 | 엑스-켐, 인크. | Dna―코딩된 라이브러리의 생성 및 스크리닝 방법 |
WO2010150103A2 (en) | 2009-06-22 | 2010-12-29 | Universite De Strasbourg | Method of preparing an adduct |
WO2011050000A2 (en) * | 2009-10-20 | 2011-04-28 | The Regents Of The University Of California | Single molecule nucleic acid nanoparticles |
US11225655B2 (en) | 2010-04-16 | 2022-01-18 | Nuevolution A/S | Bi-functional complexes and methods for making and using such complexes |
WO2013036810A1 (en) | 2011-09-07 | 2013-03-14 | X-Chem, Inc. | Methods for tagging dna-encoded libraries |
EP2859139B1 (de) | 2012-06-06 | 2018-08-01 | The Trustees Of Princeton University | Dns-barcoding von designer-mononukleosom- und chromatinarray-bibliotheken zur profilierung von chromatinlesern, -schreibern, -löschern und -modulatoren |
IL236633B (en) | 2012-07-13 | 2022-07-01 | X Chem Inc | DNA-encoded libraries containing a conjugate containing conjugated oligonucleotide links |
GB201322692D0 (en) | 2013-12-20 | 2014-02-05 | Philochem Ag | Production of encoded chemical libraries |
DE102014213783B3 (de) * | 2014-07-16 | 2015-06-18 | Technische Universität Dresden | Verfahren zur Identifizierung hochaffiner Komplexe aus zwei Liganden und einem Rezeptor, Vorrichtung zur Durchführung des Verfahrens und selbst-assemblierende chemische Bibliothek zur Verwendung in dem Verfahren |
WO2016074683A1 (en) | 2014-11-11 | 2016-05-19 | Lundorf Pedersen Materials Aps | Method for identification of molecules with desired characteristics |
NL2013857B1 (en) * | 2014-11-21 | 2016-10-11 | Piculet Biosciences Tech B V | Self-assembled bivalent ligand complex (SABLC) libraries and methods for screening such libraries. |
JP7283727B2 (ja) | 2016-06-16 | 2023-05-30 | ヘイスタック サイエンシィズ コーポレーション | コードプローブ分子のコンビナトリアル合成が指令されかつ記録されたオリゴヌクレオチド |
US11795580B2 (en) | 2017-05-02 | 2023-10-24 | Haystack Sciences Corporation | Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same |
CN108866635B (zh) * | 2017-05-09 | 2021-11-26 | 安升(上海)医药科技有限公司 | 多特异性蛋白药物及其文库、以及制备方法和应用 |
CN109468310B (zh) * | 2018-10-25 | 2020-12-01 | 深圳劲宇生物科技有限公司 | Dna编码碎片分子库的合成方法和连接基团的筛选方法 |
GB201821109D0 (en) | 2018-12-21 | 2019-02-06 | Philochem Ag | Nucleic acid encoded chemical libraries |
KR102376443B1 (ko) | 2020-02-26 | 2022-03-17 | 포항공과대학교 산학협력단 | 나노구조체, 나노구조체를 포함하는 바이오센서, 및 스크리닝 방법 |
US20230357757A1 (en) | 2020-10-23 | 2023-11-09 | Eth Zurich | Self-purified nucleic acid encoded libraries |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8927365D0 (en) * | 1989-12-04 | 1990-01-31 | Ici Plc | Reagent |
US5573905A (en) * | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
US5695937A (en) * | 1995-09-12 | 1997-12-09 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
US20020028442A1 (en) * | 1997-05-09 | 2002-03-07 | Christian Miculka | Novel substance library and supramolecular complexes produced therewith |
DE19619373A1 (de) | 1996-05-14 | 1997-11-20 | Hoechst Ag | Neue Substanzbibliothek und damit hergestellte supramolekulare Komplexe |
DE19741716A1 (de) * | 1997-09-22 | 1999-03-25 | Hoechst Ag | Adressierbares modulares Erkennungssystem, seine Herstellung und Verwendung |
US6087103A (en) * | 1998-03-04 | 2000-07-11 | Lifespan Biosciences, Inc. | Tagged ligand arrays for identifying target-ligand interactions |
US7479472B1 (en) * | 1998-10-19 | 2009-01-20 | The Board Of Trustees Of The Leland Stanford Junior University | DNA-templated combinatorial library chemistry |
US20040058373A1 (en) * | 2001-01-31 | 2004-03-25 | Winkler Matthew M. | Competitive amplification of fractionated targets from multiple nucleic acid samples |
WO2002074929A2 (en) * | 2001-03-19 | 2002-09-26 | President And Fellows Of Harvard College | Evolving new molecular function |
AU2002360272A1 (en) * | 2001-10-10 | 2003-04-22 | Superarray Bioscience Corporation | Detecting targets by unique identifier nucleotide tags |
DE60231436D1 (de) | 2002-03-08 | 2009-04-16 | Eidgenoess Tech Hochschule | Kodierte, selbst-assemblierende chemische bibliotheken (esachel) |
-
2002
- 2002-04-15 DE DE60231436T patent/DE60231436D1/de not_active Expired - Lifetime
- 2002-04-15 US US10/507,140 patent/US20060154246A1/en not_active Abandoned
- 2002-04-15 ES ES02735257T patent/ES2321067T3/es not_active Expired - Lifetime
- 2002-04-15 EA EA200401107A patent/EA006965B1/ru not_active IP Right Cessation
- 2002-04-15 WO PCT/EP2002/004153 patent/WO2003076943A1/en not_active Application Discontinuation
- 2002-04-15 DK DK02735257T patent/DK1483585T3/da active
- 2002-04-15 AU AU2002310846A patent/AU2002310846B2/en not_active Expired
- 2002-04-15 EP EP02735257A patent/EP1483585B1/de not_active Expired - Lifetime
- 2002-04-15 AT AT02735257T patent/ATE424561T1/de active
- 2002-04-15 KR KR1020047014042A patent/KR100916889B1/ko active IP Right Grant
- 2002-04-15 CA CA2478203A patent/CA2478203C/en not_active Expired - Lifetime
-
2003
- 2003-03-05 US US10/382,107 patent/US20040014090A1/en not_active Abandoned
-
2005
- 2005-04-20 HK HK05103364.7A patent/HK1070427A1/xx not_active IP Right Cessation
-
2009
- 2009-09-08 US US12/555,707 patent/US8642514B2/en not_active Expired - Fee Related
- 2009-11-05 US US12/613,475 patent/US8673824B2/en not_active Expired - Lifetime
-
2014
- 2014-01-14 US US14/155,031 patent/US9783843B2/en active Active
-
2017
- 2017-09-01 US US15/694,712 patent/US10895019B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2321067T3 (es) | 2009-06-02 |
US20110319278A1 (en) | 2011-12-29 |
KR20050002846A (ko) | 2005-01-10 |
US20060154246A1 (en) | 2006-07-13 |
EP1483585B1 (de) | 2009-03-04 |
US20180245141A1 (en) | 2018-08-30 |
US10895019B2 (en) | 2021-01-19 |
AU2002310846B2 (en) | 2008-03-20 |
KR100916889B1 (ko) | 2009-09-09 |
EA200401107A1 (ru) | 2005-04-28 |
US8673824B2 (en) | 2014-03-18 |
US20140128290A1 (en) | 2014-05-08 |
AU2002310846A1 (en) | 2003-09-22 |
CA2478203A1 (en) | 2003-09-18 |
US20040014090A1 (en) | 2004-01-22 |
US9783843B2 (en) | 2017-10-10 |
DK1483585T3 (da) | 2009-06-22 |
ATE424561T1 (de) | 2009-03-15 |
US8642514B2 (en) | 2014-02-04 |
US20100184611A1 (en) | 2010-07-22 |
CA2478203C (en) | 2011-06-14 |
WO2003076943A1 (en) | 2003-09-18 |
EP1483585A1 (de) | 2004-12-08 |
EA006965B1 (ru) | 2006-06-30 |
HK1070427A1 (en) | 2005-06-17 |
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