DE60306527D1 - Implantierbares mems medikamentenverabreichungssystem - Google Patents

Implantierbares mems medikamentenverabreichungssystem

Info

Publication number
DE60306527D1
DE60306527D1 DE60306527T DE60306527T DE60306527D1 DE 60306527 D1 DE60306527 D1 DE 60306527D1 DE 60306527 T DE60306527 T DE 60306527T DE 60306527 T DE60306527 T DE 60306527T DE 60306527 D1 DE60306527 D1 DE 60306527D1
Authority
DE
Germany
Prior art keywords
membrane
rupture
predetermined
administration system
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60306527T
Other languages
English (en)
Other versions
DE60306527T2 (de
Inventor
T Cho
Keith Cromack
James Jara-Almonte
J Verlee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hospira Inc
Original Assignee
Hospira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hospira Inc filed Critical Hospira Inc
Publication of DE60306527D1 publication Critical patent/DE60306527D1/de
Application granted granted Critical
Publication of DE60306527T2 publication Critical patent/DE60306527T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
DE60306527T 2002-07-30 2003-07-29 Implantierbares mems medikamentenverabreichungssystem Expired - Fee Related DE60306527T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US207934 2002-07-30
US10/207,934 US6953455B2 (en) 2002-07-30 2002-07-30 Medicine delivery system
PCT/US2003/023612 WO2004010971A1 (en) 2002-07-30 2003-07-29 Implantable mems medicine delivery system

Publications (2)

Publication Number Publication Date
DE60306527D1 true DE60306527D1 (de) 2006-08-10
DE60306527T2 DE60306527T2 (de) 2007-02-08

Family

ID=31186743

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60306527T Expired - Fee Related DE60306527T2 (de) 2002-07-30 2003-07-29 Implantierbares mems medikamentenverabreichungssystem

Country Status (9)

Country Link
US (1) US6953455B2 (de)
EP (1) EP1526836B1 (de)
JP (1) JP2006500086A (de)
AT (1) ATE331501T1 (de)
AU (1) AU2003256946B2 (de)
CA (1) CA2494198A1 (de)
DE (1) DE60306527T2 (de)
ES (1) ES2266873T3 (de)
WO (1) WO2004010971A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2358296A1 (en) * 1999-01-05 2000-07-13 Anthony P. Adamis Targeted transscleral controlled release drug delivery to the retina and choroid
US6682521B2 (en) * 2000-03-23 2004-01-27 Dennis N. Petrakis Temperature activated systems
US7445616B2 (en) * 2001-03-23 2008-11-04 Petrakis Dennis N Temperature responsive systems
US7607402B2 (en) 2001-03-23 2009-10-27 Petrakis Dennis N Temperature responsive systems
US7655001B2 (en) * 2001-03-23 2010-02-02 Petrakis Dennis N Temperature responsive systems
AU2003217531A1 (en) * 2002-05-02 2003-11-17 Massachusetts Eye And Ear Infirmary Ocular drug delivery systems and use thereof
WO2004073551A2 (en) * 2003-02-18 2004-09-02 Massachusetts Eye And Ear Infirmary Transscleral drug delivery device and related methods
US7476224B2 (en) * 2003-03-17 2009-01-13 Petrakis Dennis N Temperature responsive systems
GB2418144A (en) * 2004-09-17 2006-03-22 Psimedica Ltd Medical device for delivery of beneficial substance
WO2007042961A2 (en) * 2005-10-11 2007-04-19 Koninklijke Philips Electronics N.V. Device for controlled release of chemical molecules
US7968426B1 (en) * 2005-10-24 2011-06-28 Microwave Bonding Instruments, Inc. Systems and methods for bonding semiconductor substrates to metal substrates using microwave energy
EP2029216A1 (de) * 2006-06-02 2009-03-04 Koninklijke Philips Electronics N.V. Vorrichtung zur kontrollierten freisetzung einer substanz
CA2672602C (en) 2006-12-18 2014-05-20 Electronic Dietary Foods Inc. Device for delivery of a substance
DE102007032688A1 (de) * 2007-07-13 2009-01-22 Biotronik Vi Patent Ag Implantat und System aus einem Implantat und einer Anregungsvorrichtung
US20090259217A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems associated with delivery of one or more agents to an individual
US20090259214A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Agent delivery device
FR2945097B1 (fr) * 2009-04-30 2011-06-03 Commissariat Energie Atomique Vanne microfluidique a usage unique.
US8551096B2 (en) * 2009-05-13 2013-10-08 Boston Scientific Scimed, Inc. Directional delivery of energy and bioactives
US9314571B1 (en) 2012-02-10 2016-04-19 Mphase Technologies, Inc. Drug delivery system
ES2741348T3 (es) 2012-03-13 2020-02-10 Becton Dickinson France Dispositivo de inyección que tiene una porción de administración de fármaco miniaturizada
SG11201504886SA (en) * 2012-12-21 2015-07-30 Microchips Biotech Inc Implantable medical device for minimally-invasive insertion
CA2946739A1 (en) * 2014-04-25 2015-10-29 Johnson & Johnson Vision Care, Inc. Method and ophthalmic device with active agent release system
US9937124B2 (en) 2014-09-11 2018-04-10 International Business Machines Corporation Microchip substance delivery devices having low-power electromechanical release mechanisms
AU2015364280A1 (en) 2014-12-18 2017-07-06 Windgap Medical, Inc. Method and compositions for dissolving or solubilizing therapeutic agents
US10881788B2 (en) * 2015-10-30 2021-01-05 International Business Machines Corporation Delivery device including reactive material for programmable discrete delivery of a substance
US9867932B2 (en) 2015-10-30 2018-01-16 International Business Machines Corporation Drug delivery device having a cavity sealed by a pressurized membrane
EP3402558B1 (de) * 2016-01-11 2023-11-29 Syqe Medical Ltd. Persönliche verdampfungsvorrichtung
US10508755B2 (en) * 2017-07-21 2019-12-17 International Business Machines Corporation Fluid delivery device with hydrophobic surface
US20230027746A1 (en) * 2019-12-13 2023-01-26 Massachusetts Institute Of Technology Dispensing device with membrane based trigger
CN112472975B (zh) * 2020-11-19 2022-04-12 华中科技大学 一种宫内药物控释系统
US20230065107A1 (en) * 2021-09-02 2023-03-02 International Business Machines Corporation Implant device with mems (microelectromechanical system) actuated membrane

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198135A (en) * 1979-04-04 1980-04-15 Polaroid Corporation Method and apparatus for releasing processing fluid from a fluid applicator by application of thermal energy
US5059175A (en) * 1990-10-09 1991-10-22 University Of Utah Research Foundation Implantable drug delivery system with piston actuation
US5167625A (en) * 1990-10-09 1992-12-01 Sarcos Group Multiple vesicle implantable drug delivery system
US5391164A (en) * 1991-05-03 1995-02-21 Giampapa; Vincent C. Subcutaneous implantable multiple-agent delivery system
US5366454A (en) * 1993-03-17 1994-11-22 La Corporation De L'ecole Polytechnique Implantable medication dispensing device
US5368704A (en) * 1993-08-06 1994-11-29 Teknekron Corporation Micro-electrochemical valves and method
DE19610293C1 (de) * 1996-03-15 1997-07-31 Fraunhofer Ges Forschung Vorrichtung zur gekapselten Aufnahme eines Materials
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
SK284825B6 (sk) * 1996-11-21 2005-12-01 Laboratoires D'hygiene Et De Dietetique (L.H.D.) Miniatúrny ventil na plnenie napájacieho zásobníka aparátu na transdermálnu aplikáciu lieku
US20030036746A1 (en) * 2001-08-16 2003-02-20 Avi Penner Devices for intrabody delivery of molecules and systems and methods utilizing same
DE60018582T2 (de) * 1999-08-18 2006-01-19 Microchips, Inc., Bedford Thermisch aktivierbarer microchip als abgabevorrichtung für chemikalien
EP2308522A3 (de) 1999-11-17 2012-02-29 Boston Scientific Limited Miniaturisierte Vorrichtungen zur Abgabe von Molekülen in einer Trägerflüssigkeit
US6808522B2 (en) * 1999-12-10 2004-10-26 Massachusetts Institute Of Technology Microchip devices for delivery of molecules and methods of fabrication thereof
ATE499988T1 (de) * 2000-03-02 2011-03-15 Microchips Inc Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien
WO2001091902A2 (en) * 2000-05-30 2001-12-06 Massachusetts Institute Of Technology Methods and devices for sealing microchip reservoir devices
DE60116520T2 (de) * 2000-10-10 2006-08-31 Microchips, Inc., Bedford Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten
US6858220B2 (en) * 2001-02-28 2005-02-22 Second Sight Medical Products, Inc. Implantable microfluidic delivery system using ultra-nanocrystalline diamond coating
WO2002096389A1 (en) * 2001-05-30 2002-12-05 Microchips, Inc. Conformal coated microchip reservoir devices
WO2002099457A1 (en) 2001-05-31 2002-12-12 Massachusetts Inst Technology Microchip devices with improved reservoir opening
EP1399135B1 (de) * 2001-06-28 2004-12-29 Microchips, Inc. Verfahren zum hermetischen versiegeln von mikrochip-reservoir-vorrichtungen
US7037580B2 (en) * 2001-09-25 2006-05-02 Ali Razavi Pattern adhesive sealing films and mats for multi-well plates
WO2003048665A1 (en) * 2001-12-03 2003-06-12 Massachusetts Institute Of Technology Microscale lyophilization and drying methods for the stabilization of molecules
US7236821B2 (en) * 2002-02-19 2007-06-26 Cardiac Pacemakers, Inc. Chronically-implanted device for sensing and therapy
US6708050B2 (en) * 2002-03-28 2004-03-16 3M Innovative Properties Company Wireless electrode having activatable power cell
US6838640B2 (en) * 2002-05-13 2005-01-04 The Regents Of The University Of Michigan Separation microcolumn assembly for a microgas chromatograph and the like

Also Published As

Publication number Publication date
CA2494198A1 (en) 2004-02-05
EP1526836B1 (de) 2006-06-28
AU2003256946B2 (en) 2008-05-15
ATE331501T1 (de) 2006-07-15
ES2266873T3 (es) 2007-03-01
DE60306527T2 (de) 2007-02-08
WO2004010971A1 (en) 2004-02-05
EP1526836A1 (de) 2005-05-04
AU2003256946A1 (en) 2004-02-16
US6953455B2 (en) 2005-10-11
JP2006500086A (ja) 2006-01-05
US20040024382A1 (en) 2004-02-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee