DE60311961D1 - Detektionsverfahren für papillomavirus mrna - Google Patents
Detektionsverfahren für papillomavirus mrnaInfo
- Publication number
- DE60311961D1 DE60311961D1 DE60311961T DE60311961T DE60311961D1 DE 60311961 D1 DE60311961 D1 DE 60311961D1 DE 60311961 T DE60311961 T DE 60311961T DE 60311961 T DE60311961 T DE 60311961T DE 60311961 D1 DE60311961 D1 DE 60311961D1
- Authority
- DE
- Germany
- Prior art keywords
- papilloma virus
- detection procedure
- virus mrna
- mrna
- risk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/708—Specific hybridization probes for papilloma
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0200239A GB0200239D0 (en) | 2002-01-07 | 2002-01-07 | Method for detecting human papillomavirus mRNA |
GB0200239 | 2002-01-07 | ||
GB0214124 | 2002-06-19 | ||
GB0214124A GB0214124D0 (en) | 2002-06-19 | 2002-06-19 | Method for detecting human papillomavirus mRNA |
PCT/GB2003/000034 WO2003057914A2 (en) | 2002-01-07 | 2003-01-07 | METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60311961D1 true DE60311961D1 (de) | 2007-04-05 |
DE60311961T2 DE60311961T2 (de) | 2007-10-18 |
Family
ID=26246916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60311961T Expired - Lifetime DE60311961T2 (de) | 2002-01-07 | 2003-01-07 | Detektionsverfahren für papillomavirus mrna |
Country Status (21)
Country | Link |
---|---|
US (4) | US7553623B2 (de) |
EP (5) | EP2272988A3 (de) |
JP (2) | JP4558322B2 (de) |
CN (1) | CN100422342C (de) |
AT (1) | ATE354677T1 (de) |
AU (2) | AU2003201639C1 (de) |
BR (1) | BR0306723A (de) |
CA (1) | CA2472026A1 (de) |
CY (1) | CY1106621T1 (de) |
DE (1) | DE60311961T2 (de) |
DK (2) | DK1463839T3 (de) |
EA (1) | EA006975B1 (de) |
ES (2) | ES2282599T3 (de) |
HK (1) | HK1065827A1 (de) |
IL (2) | IL162722A0 (de) |
MX (1) | MXPA04006440A (de) |
NO (1) | NO20042769L (de) |
NZ (1) | NZ533703A (de) |
PT (1) | PT1463839E (de) |
SI (1) | SI1463839T1 (de) |
WO (1) | WO2003057914A2 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
US20110111389A1 (en) * | 2001-11-07 | 2011-05-12 | Diagcor Bioscience Incorporation Limited | Rapid genotyping analysis for human papillomavirus and the device thereof |
DK1463839T3 (da) * | 2002-01-07 | 2007-07-02 | Norchip As | Fremgangsmåde til detektering af human papillomavirus mRNA |
EP1369694A1 (de) * | 2002-04-09 | 2003-12-10 | MTM Laboratories AG | Verfahren zur Unterscheidung zwischen Metaplasien und neoplastischen oder präneoplastischen Läsionen |
EP1507148B1 (de) * | 2003-08-25 | 2005-02-23 | MTM Laboratories AG | Verfahren zum Nachweis von Karzinomen in solubilisierten zervikalen Körperproben |
DE602004021569D1 (de) * | 2003-03-07 | 2009-07-30 | Univ New Jersey Med | Optisch dekodierbare mikroträger, arrays und verfahren |
US7361460B2 (en) * | 2003-04-11 | 2008-04-22 | Digene Corporation | Approach to molecular diagnosis of human papillomavirus-related diseases |
EP1510820B1 (de) * | 2003-08-25 | 2010-03-17 | MTM Laboratories AG | Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben |
US7527948B2 (en) * | 2003-09-25 | 2009-05-05 | Third Wave Technologies, Inc. | Detection of HPV |
WO2005033333A2 (en) * | 2003-10-07 | 2005-04-14 | Dako Denmark A/S | Methods and compositions for the diagnosis of cancer |
EP1711623A4 (de) | 2003-12-22 | 2008-05-21 | Wayne John Cancer Inst | Verfahren und vorrichtung zur in-vivo-sammlung und überwachung zirkulierender biologischer komponenten |
GB0404315D0 (en) * | 2004-02-26 | 2004-03-31 | Norchip As | Improved detection of human papillomavirus |
ITMO20040126A1 (it) | 2004-05-21 | 2004-08-21 | Bioanalisi Ct Sud S N C Di Per | Sistema per la ricerca ed identificazione di agenti patogeni |
JP5192238B2 (ja) * | 2004-11-09 | 2013-05-08 | ジェン−プローブ・インコーポレーテッド | A群連鎖球菌属を検出するための組成物及び方法 |
CA2588581C (en) | 2004-12-08 | 2011-05-31 | Gen-Probe Incorporated | Detection of nucleic acids from multiple types of human papillomaviruses |
WO2007001986A2 (en) | 2005-06-20 | 2007-01-04 | Yuling Luo | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
EA014648B1 (ru) * | 2005-11-15 | 2010-12-30 | Генойд Кфт. | Способ обнаружения патогенов |
US8518639B2 (en) | 2006-04-11 | 2013-08-27 | Bio-Rad Innovations | HPV detection and quantification by real-time multiplex amplification |
US7833716B2 (en) * | 2006-06-06 | 2010-11-16 | Gen-Probe Incorporated | Tagged oligonucleotides and their use in nucleic acid amplification methods |
WO2008071998A2 (en) * | 2006-12-15 | 2008-06-19 | Oncomethylome Sciences Sa | Diagnostic methods for diseases caused by a hpv infection comprising determining the methylation status of the hpv genome |
US8198027B2 (en) * | 2006-12-21 | 2012-06-12 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
US7838215B2 (en) * | 2007-09-25 | 2010-11-23 | Canvir, Inc. | Advanced cervical cell screening methods |
CA2704151C (en) | 2007-11-01 | 2017-04-25 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg | New detection method for cervical hpvs |
JP5299986B2 (ja) * | 2007-11-01 | 2013-09-25 | 国立大学法人山口大学 | 核酸の定量方法 |
AU2009238247B2 (en) * | 2008-04-17 | 2014-12-11 | Qiagen Gaithersburg, Inc. | Compositions, methods, and kits using synthetic probes for determining the presence of a target nucleic acid |
US9090948B2 (en) | 2008-09-30 | 2015-07-28 | Abbott Molecular Inc. | Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples |
TWI417389B (zh) | 2008-10-27 | 2013-12-01 | Qiagen Gaithersburg Inc | 於自動平台上之快速結果雜交捕捉法 |
EP2184368A1 (de) | 2008-11-07 | 2010-05-12 | DKFZ Deutsches Krebsforschungszentrum | Diagnosetranskript- und Spleißmuster von HPV16 bei verschiedenen Halsverletzungen |
CN102414327B (zh) * | 2009-05-01 | 2015-04-08 | 奇亚根盖瑟斯堡股份有限公司 | 用于在样品中检测rna剪接形式的非靶向扩增方法 |
JP5826752B2 (ja) * | 2009-09-14 | 2015-12-02 | キアジェン ゲイサーズバーグ インコーポレイテッド | 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法 |
US8722328B2 (en) * | 2010-01-04 | 2014-05-13 | Qiagen Gaithersburg, Inc. | Methods, compositions, and kits for recovery of nucleic acids or proteins from fixed tissue samples |
BR112012018545A2 (pt) | 2010-01-29 | 2016-05-03 | Qiagen Gaithersburg Inc | método de determinação e confirmação da presença de um hpv em uma amostra |
ES2615728T3 (es) * | 2010-01-29 | 2017-06-08 | Qiagen Gaithersburg, Inc. | Métodos y composiciones para una purificación y un análisis múltiple específico de secuencia de ácidos nucleicos |
US20110275698A1 (en) * | 2010-05-10 | 2011-11-10 | Norchip A/S | "test and treat" strategy for treating transforming hpv infection |
AU2011255638B2 (en) | 2010-05-19 | 2016-08-25 | Qiagen Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
CA2799205A1 (en) | 2010-05-25 | 2011-12-01 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
CN104849472A (zh) | 2010-10-21 | 2015-08-19 | 领先细胞医疗诊断有限公司 | 用于原位检测核酸的超灵敏方法 |
WO2012094682A2 (en) * | 2011-01-07 | 2012-07-12 | Qiagen Gaithersburg, Inc. | Materials and method for genotyping and quantifying a high-risk human papillomavirus |
DK2668290T3 (en) * | 2011-01-28 | 2017-09-18 | Advanced Cell Diagnostics Inc | RNASCOPE® HPV ASSAY FOR DETERMINING HPV STATUS OF CANCER AND HEALTH CANCER AND LESSIONS |
JP2014511182A (ja) | 2011-02-24 | 2014-05-15 | キアゲン ガイサーズバーグ アイエヌシー. | Hpv核酸を検出するための材料及び方法 |
US20130095474A1 (en) * | 2011-10-13 | 2013-04-18 | Joseph Mamone | Design of stem-loop probes and utilization in snp genotyping |
CA2854165C (en) | 2011-11-03 | 2022-11-22 | Qiagen Gaithersburg, Inc. | Materials and method for immobilizing, isolating, and concentrating cells using carboxylated surfaces |
CN102864224A (zh) * | 2012-09-11 | 2013-01-09 | 南京大学 | 一种血清microRNAs试剂盒及其应用 |
GB201310933D0 (en) | 2013-06-19 | 2013-07-31 | Norchip As | A method of cervical screening |
CA2932859A1 (en) * | 2013-12-05 | 2015-06-11 | Optipharm. Co., Ltd. | Improved cervical cancer diagnosing method and diagnostic kit for same |
WO2016005789A1 (en) * | 2014-07-07 | 2016-01-14 | Institut Pasteur | Broad range gene and genotype papillomavirus transcriptome as a biomarker of papillomavirus- associated cancer stages |
CN106048014B (zh) * | 2016-06-07 | 2019-12-10 | 博奥生物集团有限公司 | 一种用于实时检测nasba产物的高特异探针 |
US20190112673A1 (en) * | 2017-05-10 | 2019-04-18 | Genomic Vision | Association between integration of high-risk hpv genomes detected by molecular combing and the severity and/or clinical outcome of cervical lesions |
JP6831772B2 (ja) | 2017-12-22 | 2021-02-17 | 株式会社Subaru | 画像投影装置 |
CN114214343A (zh) * | 2021-11-15 | 2022-03-22 | 上海市东方医院(同济大学附属东方医院) | 一组高危型HPV整合所致的宫颈癌中特异表达的mRNA序列 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE76429T1 (de) | 1986-03-21 | 1992-06-15 | Pasteur Institut | Bestimmte, von einem papillomavirus-genom abgeleitete dns-sequenzen, deren anwendungen fuer in vitro-diagnostische zwecke und die herstellung von antigenzusammensetzungen. |
DE3853678T2 (de) * | 1987-02-26 | 1995-08-31 | Univ Sydney | Verfahren zum nachweis des karzinogenen menschlichen papillomavirus. |
US5182377A (en) | 1988-09-09 | 1993-01-26 | Hoffmann-La Roche Inc. | Probes for detection of human papillomavirus |
US5639871A (en) * | 1988-09-09 | 1997-06-17 | Roche Molecular Systems, Inc. | Detection of human papillomavirus by the polymerase chain reaction |
DE3838269A1 (de) * | 1988-11-11 | 1990-05-17 | Behringwerke Ag | Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen |
US5234809A (en) | 1989-03-23 | 1993-08-10 | Akzo N.V. | Process for isolating nucleic acid |
NL8900725A (nl) | 1989-03-23 | 1990-10-16 | Az Univ Amsterdam | Werkwijze en combinatie van middelen voor het isoleren van nucleinezuur. |
JP2791685B2 (ja) | 1989-06-08 | 1998-08-27 | 寳酒造株式会社 | パピローマウイルスの検出方法 |
US5580970A (en) * | 1989-12-01 | 1996-12-03 | Amoco Corporation | Detection of HPV transcripts |
AU6966991A (en) * | 1989-12-01 | 1991-06-26 | Gene-Trak Systems | Detection of hpv transcripts |
NL9000134A (nl) | 1990-01-19 | 1991-08-16 | Stichting Res Fonds Pathologie | Primers en werkwijze voor het detecteren van humaan papilloma virus genotypen m.b.v. pcr. |
US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
US5506105A (en) * | 1991-12-10 | 1996-04-09 | Dade International Inc. | In situ assay of amplified intracellular mRNA targets |
JPH07508891A (ja) * | 1993-05-06 | 1995-10-05 | デイド、インターナショナル、インコーポレイテッド | ヒト乳頭種ウイルス検出アッセイ |
US6174668B1 (en) * | 1993-05-14 | 2001-01-16 | Johnson & Johnson Clinical Diagnostics, Inc. | Diagnostic compositions, elements, methods and test kits for amplification and detection of two or more target DNA's using primers having matched melting temperatures |
AU697841B2 (en) | 1993-11-12 | 1998-10-15 | Phri Properties, Inc. | Hybridization probes for nucleic acid detection, universal stems, methods and kits |
DE4431174A1 (de) * | 1994-09-01 | 1996-03-07 | Deutsches Krebsforsch | Nachweisverfahren für tumorspezifische mRNA |
DE19506561C1 (de) * | 1995-02-24 | 1996-10-10 | Deutsches Krebsforsch | Verfahren zur Früherkennung von HPV-assoziierten Karzinomen bzw. von hochgradigen, durch HPV-verursachten Dysplasien |
AU726047B2 (en) * | 1995-11-15 | 2000-10-26 | Gen-Probe Incorporated | Nucleic acid probes complementary to human papillomavirus nucleic acid and related methods and kits |
US6027981A (en) | 1997-10-27 | 2000-02-22 | Texas Instruments - Acer Incorporated | Method for forming a DRAM cell with a fork-shaped capacitor |
BR9814271A (pt) * | 1997-12-12 | 2001-03-20 | Digene Corp | Determinação de doenças relacionadas com o vìrus do papiloma humano |
WO2000000638A2 (en) | 1998-06-26 | 2000-01-06 | Akzo Nobel N.V. | Tagging of rna amplicons generated by transcription-based amplification |
AU2001249526A1 (en) * | 2000-03-28 | 2001-10-08 | Biosearch International Pty Ltd | Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome |
US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
GB0018050D0 (en) * | 2000-07-21 | 2000-09-13 | Norchip As | Detection of human papillomavirus mRNA |
WO2003019143A2 (en) * | 2001-08-23 | 2003-03-06 | Merck & Co., Inc. | Fluorescent multiplex hpv pcr assays using multiple fluorophores |
DK1463839T3 (da) | 2002-01-07 | 2007-07-02 | Norchip As | Fremgangsmåde til detektering af human papillomavirus mRNA |
GB0200258D0 (en) | 2002-01-07 | 2002-02-20 | Norchip As | Detection of human papillomavirus |
GB0404315D0 (en) * | 2004-02-26 | 2004-03-31 | Norchip As | Improved detection of human papillomavirus |
-
2003
- 2003-01-07 DK DK03700338T patent/DK1463839T3/da active
- 2003-01-07 EP EP10184464A patent/EP2272988A3/de not_active Withdrawn
- 2003-01-07 EP EP06075498.3A patent/EP1715062B1/de not_active Expired - Lifetime
- 2003-01-07 EP EP03700338A patent/EP1463839B1/de not_active Expired - Lifetime
- 2003-01-07 BR BR0306723-8A patent/BR0306723A/pt not_active IP Right Cessation
- 2003-01-07 SI SI200330775T patent/SI1463839T1/sl unknown
- 2003-01-07 ES ES03700338T patent/ES2282599T3/es not_active Expired - Lifetime
- 2003-01-07 DE DE60311961T patent/DE60311961T2/de not_active Expired - Lifetime
- 2003-01-07 MX MXPA04006440A patent/MXPA04006440A/es active IP Right Grant
- 2003-01-07 EA EA200400919A patent/EA006975B1/ru not_active IP Right Cessation
- 2003-01-07 NZ NZ533703A patent/NZ533703A/en not_active IP Right Cessation
- 2003-01-07 CN CNB038053802A patent/CN100422342C/zh not_active Expired - Fee Related
- 2003-01-07 IL IL16272203A patent/IL162722A0/xx unknown
- 2003-01-07 AU AU2003201639A patent/AU2003201639C1/en not_active Ceased
- 2003-01-07 US US10/500,832 patent/US7553623B2/en not_active Expired - Fee Related
- 2003-01-07 AT AT03700338T patent/ATE354677T1/de active
- 2003-01-07 EP EP15158266.5A patent/EP2913407B1/de not_active Expired - Lifetime
- 2003-01-07 CA CA002472026A patent/CA2472026A1/en not_active Abandoned
- 2003-01-07 EP EP10184669.9A patent/EP2267155B2/de not_active Expired - Lifetime
- 2003-01-07 WO PCT/GB2003/000034 patent/WO2003057914A2/en active Application Filing
- 2003-01-07 ES ES15158266.5T patent/ES2654909T3/es not_active Expired - Lifetime
- 2003-01-07 JP JP2003558207A patent/JP4558322B2/ja not_active Expired - Fee Related
- 2003-01-07 DK DK15158266.5T patent/DK2913407T3/en active
- 2003-01-07 PT PT03700338T patent/PT1463839E/pt unknown
-
2004
- 2004-06-24 IL IL162722A patent/IL162722A/en not_active IP Right Cessation
- 2004-06-30 NO NO20042769A patent/NO20042769L/no not_active Application Discontinuation
- 2004-11-04 HK HK04108678A patent/HK1065827A1/xx not_active IP Right Cessation
-
2007
- 2007-05-21 CY CY20071100705T patent/CY1106621T1/el unknown
-
2008
- 2008-08-14 AU AU2008205436A patent/AU2008205436A1/en not_active Abandoned
-
2009
- 2009-06-12 US US12/483,860 patent/US8420314B2/en not_active Expired - Lifetime
- 2009-06-12 US US12/483,900 patent/US7812144B2/en not_active Expired - Lifetime
-
2010
- 2010-01-04 JP JP2010000207A patent/JP5204132B2/ja not_active Expired - Fee Related
-
2013
- 2013-03-11 US US13/792,414 patent/US20130309658A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |