DE60316913D1 - Nicotinamide und deren verwendung als p38 inhibitoren - Google Patents
Nicotinamide und deren verwendung als p38 inhibitorenInfo
- Publication number
- DE60316913D1 DE60316913D1 DE60316913T DE60316913T DE60316913D1 DE 60316913 D1 DE60316913 D1 DE 60316913D1 DE 60316913 T DE60316913 T DE 60316913T DE 60316913 T DE60316913 T DE 60316913T DE 60316913 D1 DE60316913 D1 DE 60316913D1
- Authority
- DE
- Germany
- Prior art keywords
- inhibitors
- nicotinamides
- kinase
- activity
- mediated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0203301 | 2002-02-12 | ||
GBGB0203301.7A GB0203301D0 (en) | 2002-02-12 | 2002-02-12 | Novel compounds |
GB0225385A GB0225385D0 (en) | 2002-10-31 | 2002-10-31 | Novel compounds |
GB0225385 | 2002-10-31 | ||
PCT/GB2003/000554 WO2003068747A1 (en) | 2002-02-12 | 2003-02-10 | Nicotinamide derivates useful as p38 inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60316913D1 true DE60316913D1 (de) | 2007-11-29 |
DE60316913T2 DE60316913T2 (de) | 2008-11-20 |
Family
ID=27736200
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60316913T Expired - Lifetime DE60316913T2 (de) | 2002-02-12 | 2003-02-10 | Nicotinamide und deren verwendung als p38 inhibitoren |
DE60334651T Expired - Lifetime DE60334651D1 (de) | 2002-02-12 | 2003-02-10 | Nicotinamide und deren Verwendung als P38 Inhibitoren |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60334651T Expired - Lifetime DE60334651D1 (de) | 2002-02-12 | 2003-02-10 | Nicotinamide und deren Verwendung als P38 Inhibitoren |
Country Status (26)
Country | Link |
---|---|
US (5) | US7125898B2 (de) |
EP (3) | EP2258687B1 (de) |
JP (2) | JP4472349B2 (de) |
KR (1) | KR101058292B1 (de) |
CN (1) | CN100369898C (de) |
AT (2) | ATE375980T1 (de) |
AU (1) | AU2003207298B2 (de) |
BR (1) | BRPI0307351B8 (de) |
CA (1) | CA2474192C (de) |
CO (1) | CO5611147A2 (de) |
CY (2) | CY1107117T1 (de) |
DE (2) | DE60316913T2 (de) |
DK (2) | DK1474395T3 (de) |
ES (2) | ES2400486T3 (de) |
HK (2) | HK1113056A1 (de) |
IL (1) | IL163090A (de) |
IS (1) | IS2520B (de) |
MX (1) | MXPA04007838A (de) |
NO (1) | NO327418B1 (de) |
NZ (1) | NZ533865A (de) |
PL (1) | PL212910B1 (de) |
PT (2) | PT1864975E (de) |
RU (1) | RU2309951C2 (de) |
SI (2) | SI1864975T1 (de) |
WO (1) | WO2003068747A1 (de) |
ZA (1) | ZA200405602B (de) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0124934D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124931D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124939D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124933D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
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