DE60325888D1 - Verwendung von loxapine für die herstellung eines mittels zur behandlung von schmerz - Google Patents

Verwendung von loxapine für die herstellung eines mittels zur behandlung von schmerz

Info

Publication number
DE60325888D1
DE60325888D1 DE60325888T DE60325888T DE60325888D1 DE 60325888 D1 DE60325888 D1 DE 60325888D1 DE 60325888 T DE60325888 T DE 60325888T DE 60325888 T DE60325888 T DE 60325888T DE 60325888 D1 DE60325888 D1 DE 60325888D1
Authority
DE
Germany
Prior art keywords
loxapine
manufacture
treating pain
amoxapine
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60325888T
Other languages
English (en)
Inventor
Ron L Hale
Patrik Munzar
Joshua D Rabinowitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alexza Pharmaceuticals Inc
Original Assignee
Alexza Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexza Pharmaceuticals Inc filed Critical Alexza Pharmaceuticals Inc
Application granted granted Critical
Publication of DE60325888D1 publication Critical patent/DE60325888D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE60325888T 2002-11-26 2003-11-20 Verwendung von loxapine für die herstellung eines mittels zur behandlung von schmerz Expired - Lifetime DE60325888D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42940502P 2002-11-26 2002-11-26
PCT/US2003/037415 WO2004047844A1 (en) 2002-11-26 2003-11-20 Use of loxapine and amoxapine for the manufacture of a medicament for the treatment of pain

Publications (1)

Publication Number Publication Date
DE60325888D1 true DE60325888D1 (de) 2009-03-05

Family

ID=32393557

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60325888T Expired - Lifetime DE60325888D1 (de) 2002-11-26 2003-11-20 Verwendung von loxapine für die herstellung eines mittels zur behandlung von schmerz

Country Status (15)

Country Link
US (1) US8288372B2 (de)
EP (1) EP1567164B1 (de)
JP (1) JP2006514934A (de)
CN (2) CN101371843B (de)
AT (1) ATE420647T1 (de)
AU (1) AU2003294470B2 (de)
CA (1) CA2507159A1 (de)
DE (1) DE60325888D1 (de)
DK (1) DK1567164T3 (de)
ES (1) ES2321292T3 (de)
HK (1) HK1125845A1 (de)
MX (1) MXPA05005611A (de)
NZ (1) NZ540207A (de)
PT (1) PT1567164E (de)
WO (1) WO2004047844A1 (de)

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US20130310385A1 (en) * 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US9320725B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
JP6397493B2 (ja) 2013-07-11 2018-09-26 アレックザ ファーマシューティカルズ， インコーポレイテッド メタ−サリチル酸とのニコチン塩
CN114522307A (zh) 2015-03-11 2022-05-24 艾利斯达医药品公司 气道中的防静电材料用于热气溶胶凝结方法的用途
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CN101371843A (zh) 2009-02-25
MXPA05005611A (es) 2005-07-27
ES2321292T3 (es) 2009-06-04
CN101371843B (zh) 2012-09-26
US20040102434A1 (en) 2004-05-27
AU2003294470B2 (en) 2009-09-17
NZ540207A (en) 2008-06-30
EP1567164B1 (de) 2009-01-14
WO2004047844A1 (en) 2004-06-10
WO2004047844A8 (en) 2007-01-25
CN1717237A (zh) 2006-01-04
ATE420647T1 (de) 2009-01-15
DK1567164T3 (da) 2009-05-18
US8288372B2 (en) 2012-10-16
CA2507159A1 (en) 2004-06-10
JP2006514934A (ja) 2006-05-18
EP1567164A1 (de) 2005-08-31
PT1567164E (pt) 2009-03-31
AU2003294470A1 (en) 2004-06-18
HK1125845A1 (en) 2009-08-21

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