DE69002627T2 - 99 m Tc (III) herzmuskelbildende Mittel, wirksam beim Menschen. - Google Patents

99 m Tc (III) herzmuskelbildende Mittel, wirksam beim Menschen.

Info

Publication number
DE69002627T2
DE69002627T2 DE90910036T DE69002627T DE69002627T2 DE 69002627 T2 DE69002627 T2 DE 69002627T2 DE 90910036 T DE90910036 T DE 90910036T DE 69002627 T DE69002627 T DE 69002627T DE 69002627 T2 DE69002627 T2 DE 69002627T2
Authority
DE
Germany
Prior art keywords
humans
iii
effective
cardiac muscle
building agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90910036T
Other languages
English (en)
Other versions
DE69002627D1 (de
Inventor
Edward Deutsch
Karen Libson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Cincinnati
Original Assignee
University of Cincinnati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Cincinnati filed Critical University of Cincinnati
Publication of DE69002627D1 publication Critical patent/DE69002627D1/de
Application granted granted Critical
Publication of DE69002627T2 publication Critical patent/DE69002627T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
DE90910036T 1989-05-19 1990-03-20 99 m Tc (III) herzmuskelbildende Mittel, wirksam beim Menschen. Expired - Fee Related DE69002627T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/354,491 US4917879A (en) 1989-05-19 1989-05-19 99MTC(III) myocardial imaging agents that are effective in humans

Publications (2)

Publication Number Publication Date
DE69002627D1 DE69002627D1 (de) 1993-09-09
DE69002627T2 true DE69002627T2 (de) 1993-11-11

Family

ID=23393570

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90910036T Expired - Fee Related DE69002627T2 (de) 1989-05-19 1990-03-20 99 m Tc (III) herzmuskelbildende Mittel, wirksam beim Menschen.

Country Status (10)

Country Link
US (1) US4917879A (de)
EP (1) EP0472665B1 (de)
JP (1) JPH0776182B2 (de)
AT (1) ATE92341T1 (de)
AU (1) AU633597B2 (de)
CA (1) CA2051699A1 (de)
DE (1) DE69002627T2 (de)
DK (1) DK0472665T3 (de)
ES (1) ES2058922T3 (de)
WO (1) WO1990014106A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0403524B1 (de) * 1988-03-09 1993-02-10 Cis Bio International Herstellung von als radiopharmazeutische produkte verwendbare nitruroverbindungen
US4957728A (en) * 1989-05-19 1990-09-18 University Of Cincinnati Kit for preparing Tc (III)-99m myocardial imaging agents that are effective in humans
US5908931A (en) * 1990-12-14 1999-06-01 Mallinckrodt Inc. Preorganized hexadentate ligands useful in radiographic imaging agents
US5112594A (en) * 1991-04-04 1992-05-12 Mallinckrodt Medical, Inc. Kit for preparing a technetium-99m myocardial imaging agent
US5112595A (en) * 1990-12-21 1992-05-12 Mallinckrodt Medical, Inc. 99MTC(III) myocardial imaging agents and method of use
US5300280A (en) * 1992-02-14 1994-04-05 Mallinckrodt Medical, Inc. Stabilized radiopharmaceutical kits
JPH08505398A (ja) * 1993-01-06 1996-06-11 マリンクロット・メディカル・インコーポレイテッド 放射線撮影イメージング剤に有用な六座配位子類
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
US5750088A (en) * 1993-03-30 1998-05-12 The Dupont Merck Pharmaceutical Company Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals
US5541289A (en) * 1994-03-30 1996-07-30 Washington University Phosphine containing amino acids and peptides and methods of preparing and using same
CA2166676C (en) * 1995-01-09 2007-05-01 Yasuhisa Fujibayashi Diagnostic agent for hypoxia or mitochondrial dysfunction comprising radioactive copper complex of dithiosemicarbazone derivative or diamine diol schiff base derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758682A (en) * 1983-03-17 1988-07-19 California Institute Of Technology Homogeneous coordination compounds as oxidation catalysts
CA1300608C (en) * 1985-05-10 1992-05-12 Edward A. Deutsch 99 mtc (iii) myocardial imaging agents which are non-reducable in vivo
US4795626A (en) * 1985-05-10 1989-01-03 University Of Cincinnati 99m Tc.sup.(III) myocardial imaging agents which are non-reducable in vivo
GB8723438D0 (en) * 1987-10-06 1987-11-11 Amersham Int Plc Cationic complexes of technetium-99m

Also Published As

Publication number Publication date
ATE92341T1 (de) 1993-08-15
EP0472665A1 (de) 1992-03-04
US4917879A (en) 1990-04-17
DE69002627D1 (de) 1993-09-09
AU633597B2 (en) 1993-02-04
CA2051699A1 (en) 1990-11-20
EP0472665B1 (de) 1993-08-04
AU5845390A (en) 1990-12-18
WO1990014106A2 (en) 1990-11-29
DK0472665T3 (da) 1994-01-03
ES2058922T3 (es) 1994-11-01
WO1990014106A3 (en) 1991-07-25
JPH04505622A (ja) 1992-10-01
JPH0776182B2 (ja) 1995-08-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee