DE69019817T3 - Trägermaterial zur Arzneimittelverabreichung. - Google Patents

Trägermaterial zur Arzneimittelverabreichung.

Info

Publication number
DE69019817T3
DE69019817T3 DE69019817T DE69019817T DE69019817T3 DE 69019817 T3 DE69019817 T3 DE 69019817T3 DE 69019817 T DE69019817 T DE 69019817T DE 69019817 T DE69019817 T DE 69019817T DE 69019817 T3 DE69019817 T3 DE 69019817T3
Authority
DE
Germany
Prior art keywords
carrier material
drug administration
administration
drug
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69019817T
Other languages
English (en)
Other versions
DE69019817T2 (de
DE69019817D1 (de
Inventor
Bernard Ecanow
Dilip J Gole
R Saul Levinson
John Desmond Davies
James Carbone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Janssen Pharmaceutica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27014357&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69019817(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/393,582 external-priority patent/US5039540A/en
Application filed by Janssen Pharmaceutica Inc filed Critical Janssen Pharmaceutica Inc
Application granted granted Critical
Publication of DE69019817D1 publication Critical patent/DE69019817D1/de
Publication of DE69019817T2 publication Critical patent/DE69019817T2/de
Publication of DE69019817T3 publication Critical patent/DE69019817T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C1/00Concentration, evaporation or drying
    • A23C1/06Concentration by freezing out the water
    • A23C1/08Freeze-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Freezing, Cooling And Drying Of Foods (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)
DE69019817T 1989-08-14 1990-08-14 Trägermaterial zur Arzneimittelverabreichung. Expired - Lifetime DE69019817T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/393,582 US5039540A (en) 1989-08-14 1989-08-14 Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US07/513,601 US5079018A (en) 1989-08-14 1990-04-30 Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs

Publications (3)

Publication Number Publication Date
DE69019817D1 DE69019817D1 (de) 1995-07-06
DE69019817T2 DE69019817T2 (de) 1995-10-05
DE69019817T3 true DE69019817T3 (de) 1999-06-17

Family

ID=27014357

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69019817T Expired - Lifetime DE69019817T3 (de) 1989-08-14 1990-08-14 Trägermaterial zur Arzneimittelverabreichung.

Country Status (8)

Country Link
US (1) US5079018A (de)
EP (1) EP0450141B2 (de)
JP (1) JP3303884B2 (de)
CY (1) CY1923A (de)
DE (1) DE69019817T3 (de)
DK (1) DK0450141T4 (de)
HK (1) HK118096A (de)
NO (1) NO300085B1 (de)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US5744500A (en) * 1990-01-03 1998-04-28 Teva Pharmaceutical Industries, Ltd. Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof
US5275369A (en) * 1991-01-31 1994-01-04 Ohi Seisakusho Co., Ltd. Protective cover for seat sliding devices
JP2807346B2 (ja) * 1991-12-24 1998-10-08 山之内製薬株式会社 口腔内崩壊製剤及びその製造法
GB9200247D0 (en) * 1992-01-07 1992-02-26 Erba Carlo Spa Pharmaceutical compositions containing polymer derivative-bound anthracycline glycosides and a method for their preparation
DK0701815T3 (da) * 1992-01-17 2000-02-07 Alfatec Pharma Gmbh Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr
US5876754A (en) * 1992-01-17 1999-03-02 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
EP0553777B1 (de) * 1992-01-29 2002-04-24 Takeda Chemical Industries, Ltd. Schnellösliche Tablette und ihre Herstellung
US5221545A (en) * 1992-03-09 1993-06-22 Abbott Laboratories Method of providing selenium in a nutritional product
US5242143A (en) * 1992-03-12 1993-09-07 Tachi-S Co. Ltd. Cover for slide rail of automotive seat
US5298261A (en) * 1992-04-20 1994-03-29 Oregon Freeze Dry, Inc. Rapidly distintegrating tablet
IL105553A (en) 1992-05-06 1998-01-04 Janssen Pharmaceutica Inc Solid dosage forms consisting of a porous network of matrix that releases a substance that dissipates rapidly in water
US20070116761A1 (en) * 1993-02-22 2007-05-24 Desai Neil P Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US20030068362A1 (en) * 1993-02-22 2003-04-10 American Bioscience, Inc. Methods and formulations for the delivery of pharmacologically active agents
US20030073642A1 (en) * 1993-02-22 2003-04-17 American Bioscience, Inc. Methods and formulations for delivery of pharmacologically active agents
US20030133955A1 (en) * 1993-02-22 2003-07-17 American Bioscience, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US5409703A (en) * 1993-06-24 1995-04-25 Carrington Laboratories, Inc. Dried hydrogel from hydrophilic-hygroscopic polymer
US5457895A (en) * 1993-10-01 1995-10-17 R. P. Scherer Corporation Method of identifying freeze-dried dosage forms
US5382437A (en) * 1993-10-25 1995-01-17 Hunter Research Corporation Frozen liquified gas composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
EP0705298B1 (de) * 1993-12-01 2002-03-27 Bioartificial Gel Technologies Inc. Hydrogel auf basis von albumin
PL184068B1 (pl) * 1994-08-04 2002-08-30 Quadrant Holdings Cambridge Kompozycja farmaceutyczna o wysokiej stabilności i sposób wytwarzania kompozycji farmaceutycznej o wysokiej stabilności
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
US5837287A (en) * 1994-10-28 1998-11-17 R P Scherer Corporation Process for preparing solid pharmaceutical dosage forms
GB9421837D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms
GEP20012374B (en) * 1995-03-02 2001-03-25 Scherer Ltd R P Pharmaceutical Compositions Comprising Monoamine Oxidase B Inhibitors, Method for Obtaining the Same and Use
GB9504201D0 (en) 1995-03-02 1995-04-19 Scherer Ltd R P Process for the preparation of a solid pharmaceutical dosage form
EG23659A (en) 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
US5731339A (en) * 1995-04-28 1998-03-24 Zonagen, Inc. Methods and formulations for modulating the human sexual response
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
JP3618355B2 (ja) 1995-12-26 2005-02-09 オネスタ・ニュートリション・インコーポレーテッド 食物繊維デリバリーシステム
US5686133A (en) * 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals
US6509146B1 (en) 1996-05-29 2003-01-21 Universal Preservation Technologies, Inc. Scalable long-term shelf preservation of sensitive biological solutions and suspensions
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US20070092563A1 (en) 1996-10-01 2007-04-26 Abraxis Bioscience, Inc. Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
GB9621614D0 (en) * 1996-10-17 1996-12-11 Cultech Limited Vitamin delivery
GB9702799D0 (en) * 1997-02-12 1997-04-02 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms
US20040023948A1 (en) * 1997-03-24 2004-02-05 Green Richard David Fast-dispersing dosage form containing 5-HT1 agonists
US20030004170A1 (en) * 1997-05-19 2003-01-02 Zonagen, Inc. Combination therapy for modulating the human sexual response
US20030199425A1 (en) * 1997-06-27 2003-10-23 Desai Neil P. Compositions and methods for treatment of hyperplasia
IL133672A0 (en) * 1997-06-27 2001-04-30 Vivorx Pharmaceuticals Inc Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
DE19739031A1 (de) * 1997-09-05 1999-03-11 Suwelack Nachf Dr Otto Mittel zur peroralen Verabreichung, seine Herstellung und Verwendung
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
US20040265377A1 (en) * 1997-10-27 2004-12-30 Harry Seager Solid dispersing vaccine composition for oral delivery
US7022683B1 (en) * 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
WO2000006124A2 (en) * 1998-07-30 2000-02-10 Point Biomedical Corporation A novel excipient for the lyophilization of aqueous suspensions of microparticles
US20030092652A1 (en) * 1998-08-14 2003-05-15 Maria Bruno Protected one-vial formulation for nucleic acid molecules, methods of making the same by in-line mixing, and related products and methods
JP4538150B2 (ja) 1998-08-14 2010-09-08 ヴァレンティス,インコーポレイテッド 核酸分子の保護された単一バイアル調製物、インライン混合によってそれを形成する方法、及び関連する生成物及び方法
US6482426B1 (en) 1998-09-17 2002-11-19 Zonagen, Inc. Compositions for the treatment of male erectile dysfunction
GB9904629D0 (en) * 1999-03-02 1999-04-21 Danbiosyst Uk Oral drug delivery system
US6680071B1 (en) 1999-03-03 2004-01-20 R. P. Scherer Technologies, Inc. Opioid agonist in a fast dispersing dosage form
US6090401A (en) * 1999-03-31 2000-07-18 Mcneil-Ppc, Inc. Stable foam composition
GB9908014D0 (en) * 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
DE19931708A1 (de) 1999-07-08 2001-01-18 Bayer Ag Verfahren zur Herstellung schnell zerfallender, fester pharmazeutischer Zubereitungen
DE10032456A1 (de) * 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Schnell zerfallende Darreichungsform zur Freisetzung von Wirkstoffen im Mundraum oder in Körperhöhlen
US6451328B1 (en) * 2000-08-03 2002-09-17 Color Access, Inc. Antioxidants in clusters of structured water
US6588180B2 (en) 2001-02-02 2003-07-08 R. P. Scherer Technologies, Inc. Constricted neck blister pack and apparatus and method for making the same
GB0102691D0 (en) * 2001-02-02 2001-03-21 Nestle Sa Water soluable powders and tablets
DE10107659B4 (de) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
CA2442855A1 (en) 2001-04-12 2002-10-24 Therics, Inc. Method and apparatus for engineered regenerative biostructures
US6509040B1 (en) 2001-06-22 2003-01-21 R.P. Scherer Corporation Fast dispersing dosage forms essentially free of mammalian gelatin
WO2003018665A1 (en) 2001-08-22 2003-03-06 Bioartificial Gel Technologies Inc. Process for the preparation of activated polyethylene glycols
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20030175370A1 (en) * 2002-03-07 2003-09-18 Carrington Laboratories, Inc. Dispersed solid-containing complex carbohydrate
DE10251963A1 (de) * 2002-11-08 2004-05-19 Lts Lohmann Therapie-Systeme Ag Transmucosale pharmazeutische Darreichungsform
GB0226076D0 (en) * 2002-11-08 2002-12-18 Rp Scherer Technologies Inc Improved formulations containing substituted imidazole derivatives
FI20022007A0 (fi) * 2002-11-08 2002-11-08 Juvantia Pharma Ltd Oy Oromukosaalinen valmiste ja menetelmä sen valmistamiseksi
WO2004049805A1 (ja) * 2002-12-04 2004-06-17 Sankyo Agro Company, Limited 麦類のマイコトキシン汚染抑制方法
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US7670624B2 (en) 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
US7351787B2 (en) * 2004-03-05 2008-04-01 Bioartificial Gel Technologies, Inc. Process for the preparation of activated polyethylene glycols
US7972621B2 (en) * 2004-06-03 2011-07-05 R.P. Scherer Technologies, Llc Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) * 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
JP2009523672A (ja) * 2006-01-20 2009-06-25 モノソル アールエックス リミテッド ライアビリティ カンパニー フィルムライニングを施した、包装体およびその製法
EP1897543A1 (de) 2006-08-30 2008-03-12 Euro-Celtique S.A. Buprenorphine-Waffel zur Substitutionstherapie
US20090214442A1 (en) * 2006-12-01 2009-08-27 Cephalon, Inc. Oral Transmucosal Nicotine Dosage Form
US20080131508A1 (en) * 2006-12-01 2008-06-05 Cephalon, Inc Oral transmucosal nicotine dosage form
TW200904340A (en) 2007-05-11 2009-02-01 Mannatech Inc Processing of natural polysaccharides by selected non-pathogenic microorganisms and methods of making and using the same
DE202009000862U1 (de) * 2009-01-07 2009-04-16 Klosterfrau Berlin Gmbh Dosiereinheit und Zusammensetzung zur Behandlung von entzündlichen Erkrankungen des Mund- und Rachenraums
GB0900473D0 (en) 2009-01-13 2009-02-11 Univ Gent Aqueous coacervate compositions suitable for making powders and water-soluble formulations of biologically-active agents
TWI468157B (zh) * 2009-04-29 2015-01-11 Intervet Int Bv 形成錠劑的方法,進行該方法的系統及包含該錠劑的包裝物
TWI471127B (zh) 2009-04-29 2015-02-01 Intervet Int Bv 供人類使用之口服崩解錠劑的製備方法、所製得之口服崩解錠劑、以及含有該口服崩解錠劑的包裝物
JP5309262B2 (ja) 2009-12-02 2013-10-09 アプタリス ファーマ リミテッド フェキソフェナジン・マイクロカプセル及びそれを含む組成物
TW201127375A (en) * 2010-01-08 2011-08-16 Eurand Inc Taste masked topiramate composition and an orally disintegrating tablet comprising the same
US10548839B2 (en) * 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
WO2012048333A1 (en) * 2010-10-08 2012-04-12 R.P. Scherer Technologies, Llc Oral vaccine fast-dissolving dosage form using starch
DE102010048408A1 (de) 2010-10-15 2012-04-19 Lts Lohmann Therapie-Systeme Ag Laminat mit verbessertem Wasserretentionsverhalten
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
CA2819663C (en) 2010-12-02 2019-12-24 Aptalis Pharmatech, Inc. Rapidly dispersing granules, orally disintegrating tablets and methods
US20140072671A1 (en) * 2012-06-29 2014-03-13 Adam Auerbach Multi-component oral delivery systems and uses thereof
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
EP3452023A1 (de) 2016-05-05 2019-03-13 Aquestive Therapeutics, Inc. Epinephrinzusammensetzungen mit verbesserter freisetzung
DE102017112527B4 (de) 2017-06-07 2019-01-03 Lts Lohmann Therapie-Systeme Ag Schnell zerfallende Schaumwafer mit hohem Flächengewicht
DE102017127434A1 (de) 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag Taschenförmige oral auflösende Filme mit hoher Wirkstoffbeladung
KR102076833B1 (ko) * 2018-11-30 2020-02-12 인하대학교 산학협력단 탄소 소재를 포함한 환경 친화적 전자파 차폐재 조성물의 제조방법
KR102076829B1 (ko) * 2018-11-30 2020-02-12 인하대학교 산학협력단 친환경 전자파 차폐재 조성물의 제조방법
DE102019100483A1 (de) 2019-01-10 2020-07-16 Lts Lohmann Therapie-Systeme Ag Oraler Dünnfilm
CA3146184A1 (en) * 2019-07-09 2021-01-14 Aquero Canada Ltd. Compositions, processes of production, sterilization, and health-promoting uses of lyophilized milk
KR102541470B1 (ko) * 2020-11-23 2023-06-07 주식회사 유에이치에스 버섯 유래 키토산을 이용한 가축 및 반려동물용 음수첨가제 및 이의 제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US473331A (en) * 1892-04-19 Andrew davidson mckay
US2166074A (en) * 1937-04-09 1939-07-11 Sharp & Dohme Inc Gelatinous colloids
JPS5017359A (de) * 1973-06-19 1975-02-24
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
US4343797A (en) * 1981-01-05 1982-08-10 Ecanow Charles S Synthetic whole blood and a method of making the same
DE3275121D1 (en) * 1981-12-11 1987-02-19 Wyeth John & Brother Ltd Process for preparing solid shaped articles
US4539204A (en) * 1982-10-29 1985-09-03 Neomed Inc. Gelatin based synthetic blood and a method of making the same
US4596788A (en) * 1983-02-07 1986-06-24 Neomed, Inc. Gelatin and lecithin based synthetic whole blood and a method of making the same
FR2561916B1 (fr) * 1984-03-30 1987-12-11 Lafon Labor Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
US4752466A (en) * 1987-08-31 1988-06-21 Johnson & Johnson Products, Inc. Thrombin aerosol

Also Published As

Publication number Publication date
US5079018A (en) 1992-01-07
EP0450141A1 (de) 1991-10-09
DE69019817T2 (de) 1995-10-05
EP0450141B2 (de) 1999-03-24
JPH0386837A (ja) 1991-04-11
CY1923A (en) 1997-03-07
DK0450141T4 (da) 2000-12-18
DK0450141T3 (da) 1995-07-24
DE69019817D1 (de) 1995-07-06
NO903542D0 (no) 1990-08-13
HK118096A (en) 1996-07-12
NO300085B1 (no) 1997-04-07
JP3303884B2 (ja) 2002-07-22
NO903542L (no) 1991-02-15
EP0450141B1 (de) 1995-05-31

Similar Documents

Publication Publication Date Title
DE69019817D1 (de) Trägermaterial zur Arzneimittelverabreichung.
DE3886965D1 (de) Zubereitungen zur gesteuerten Wirkstofffreisetzung.
DE68908456T2 (de) Matrix zur Wirkstoffabgabe.
EP0413281A3 (en) Drug carrier
FI901102A0 (fi) Farmaceutiska kompositioner.
FI922364A (fi) Farmaceutiska kompositioner.
DE68909242D1 (de) Adhäsives mittel zur arzneistoffabgabe.
DE68911473D1 (de) Arzneimittelformulierungen.
DE3750619T2 (de) System zur Abgabe von Arzneistoffen.
NL300047I1 (nl) Farmaceutische samenstelling.
NO912799L (no) Foradditiver for droevtyggere.
NO882897L (no) Avleveringssystem for legemidler.
DE3885232D1 (de) Löslichkeit-modulierte Arzneimittelvorrichtung.
AR240257A1 (es) Jeringa autodescartable.
FI893643A0 (fi) Farmaceutiska kompositioner.
FI883673A (fi) Farmaceutiska kompositioner.
DE69002034T2 (de) Vorrichtung mit gesteuerter Wirkstoffabgabe.
DE69012950T2 (de) Antikrebsmittel.
DE68902056T2 (de) 4-aroylimidazol-2-on enthaltende pharmazeutische zusammensetzung.
DE3888800D1 (de) Transdermales Arzneimittelpräparat.
FI883008A0 (fi) 8 -acylaminoergolin, dess framstaellning och farmaceutiska kompositioner innehaollande detsamma.
DE69003003D1 (de) Pharmazeutische Zusammensetzung.
DE3887237D1 (de) Arzneimittel.
FI885095A0 (fi) Anordning foer braennande av obraenda material.
LV5735A4 (lv) Medikamenti

Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings