DE69026328T2 - Verfahren zum Screenen von Arzneimitteln - Google Patents

Verfahren zum Screenen von Arzneimitteln

Info

Publication number
DE69026328T2
DE69026328T2 DE69026328T DE69026328T DE69026328T2 DE 69026328 T2 DE69026328 T2 DE 69026328T2 DE 69026328 T DE69026328 T DE 69026328T DE 69026328 T DE69026328 T DE 69026328T DE 69026328 T2 DE69026328 T2 DE 69026328T2
Authority
DE
Germany
Prior art keywords
screening drugs
drugs
screening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69026328T
Other languages
English (en)
Other versions
DE69026328D1 (de
Inventor
Pyare Khanna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Corp
Original Assignee
Microgenics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microgenics Corp filed Critical Microgenics Corp
Publication of DE69026328D1 publication Critical patent/DE69026328D1/de
Application granted granted Critical
Publication of DE69026328T2 publication Critical patent/DE69026328T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
DE69026328T 1989-08-15 1990-08-13 Verfahren zum Screenen von Arzneimitteln Expired - Fee Related DE69026328T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39401789A 1989-08-15 1989-08-15

Publications (2)

Publication Number Publication Date
DE69026328D1 DE69026328D1 (de) 1996-05-09
DE69026328T2 true DE69026328T2 (de) 1996-10-02

Family

ID=23557200

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69026328T Expired - Fee Related DE69026328T2 (de) 1989-08-15 1990-08-13 Verfahren zum Screenen von Arzneimitteln

Country Status (7)

Country Link
US (1) US5434052A (de)
EP (1) EP0421589B1 (de)
JP (1) JP2846433B2 (de)
AU (1) AU649958B2 (de)
CA (1) CA1335707C (de)
DE (1) DE69026328T2 (de)
ES (1) ES2088416T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19503320A1 (de) * 1995-02-02 1996-08-08 Boehringer Mannheim Gmbh Neue Benzodiazepinkonjugate
ATE211480T1 (de) * 1996-01-26 2002-01-15 Roche Diagnostics Corp Bismaleinsäureimid-vernetzer
US5976857A (en) * 1996-01-26 1999-11-02 Boehringer Mannheim Corporation Cross-linked polypeptide fragments of β-galactosidase
US5763196A (en) * 1996-01-26 1998-06-09 Boehringer Mannheim Corporation Assays using cross-linked polypeptide fragments of β-galactosidase
US6342345B1 (en) * 1997-04-02 2002-01-29 The Board Of Trustees Of The Leland Stanford Junior University Detection of molecular interactions by reporter subunit complementation
US6673554B1 (en) * 1999-06-14 2004-01-06 Trellie Bioinformatics, Inc. Protein localization assays for toxicity and antidotes thereto
DE10028204A1 (de) * 2000-06-09 2002-01-03 Aventis Pharma Gmbh Verfahren zur Auffindung von medizinisch wertvollen Wirkstoffen
CA2474130C (en) * 2002-01-29 2011-04-05 Pyare Khanna Enzyme activation protease assay
US20030228621A1 (en) * 2002-05-24 2003-12-11 Yong Qin Common ligand universal enzyme assay and compositions for use therein
US7452690B2 (en) * 2003-01-28 2008-11-18 Discoverx Corporation Protease EFC cell surface fusion protein assay
EP2812695A4 (de) * 2012-02-06 2015-12-02 Discoverx Corp Nachweis von intrazellularen bindungsereignissen durch messung der proteinfülle

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US4134792A (en) * 1976-12-06 1979-01-16 Miles Laboratories, Inc. Specific binding assay with an enzyme modulator as a labeling substance
US4375459A (en) * 1980-06-20 1983-03-01 The Regents Of The University Of California Cytoreceptor assay
EP0069450B1 (de) * 1981-06-22 1985-04-10 TECHNICON INSTRUMENTS CORPORATION (a New York corporation) Markierte Vitamin-B12-Derivate, ihre Herstellung und Verwendung
US4399228A (en) * 1981-07-30 1983-08-16 Corning Glass Works Polate competitive protein binding assay
US4708929A (en) * 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
WO1986002666A1 (en) * 1984-10-29 1986-05-09 Microgenics Corporation Methods for protein binding enzyme complementation assays
US4760029A (en) * 1984-11-19 1988-07-26 Schering Corporation Assay for D-1 antagonistic activity of neuroleptic drugs
DE3546014A1 (de) * 1985-12-24 1987-06-25 Boehringer Mannheim Gmbh Verfahren zur bestimmung der bindungskapazitaet des thyroxin bindenden tbg
US4859585A (en) * 1986-04-17 1989-08-22 Trustees Of Tufts College In-vitro methods for identifying compositions which are agonists and antagonists of estrogens
US4997771A (en) * 1987-04-27 1991-03-05 Schering Corporation Method for measuring the BZ-1 receptor binding activity in a test sample or test compound
IL85597A (en) * 1987-05-18 1992-08-18 Technicon Instr Immunoassay method and composition using conjugate of analyte and reaction intermediate for analyte capable of mediating signal generation
US4950591A (en) * 1987-08-14 1990-08-21 Cherksey Bruce D Membrane Na+ channel protein and related therapeutic compounds
AU610281B2 (en) * 1987-09-21 1991-05-16 Roche Diagnostics Corporation Solid-phase non-separation enzyme assay
CA1317861C (en) * 1987-10-02 1993-05-18 Stephen B. Friedman Homogeneous t-4 uptake assay
ES2055031T3 (es) * 1988-02-02 1994-08-16 Microgenics Corp Ensayo de enzima de preincubacion de receptor.
AU5664790A (en) * 1989-05-05 1990-11-29 Microgenics Corporation Method for protein binding enzyme complementation assays
US5328830A (en) * 1992-09-08 1994-07-12 Miles Inc. Potassium channel modulators

Also Published As

Publication number Publication date
DE69026328D1 (de) 1996-05-09
EP0421589B1 (de) 1996-04-03
JP2846433B2 (ja) 1999-01-13
JPH03175360A (ja) 1991-07-30
CA1335707C (en) 1995-05-30
EP0421589A2 (de) 1991-04-10
AU649958B2 (en) 1994-06-09
EP0421589A3 (en) 1991-12-18
AU6099390A (en) 1991-02-21
ES2088416T3 (es) 1996-08-16
US5434052A (en) 1995-07-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS CORP., INDIANAPOLIS, IND., US

8339 Ceased/non-payment of the annual fee