DE69027962D1 - Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium - Google Patents

Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium

Info

Publication number
DE69027962D1
DE69027962D1 DE69027962T DE69027962T DE69027962D1 DE 69027962 D1 DE69027962 D1 DE 69027962D1 DE 69027962 T DE69027962 T DE 69027962T DE 69027962 T DE69027962 T DE 69027962T DE 69027962 D1 DE69027962 D1 DE 69027962D1
Authority
DE
Germany
Prior art keywords
culture
cell number
compartment
sub
cell mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69027962T
Other languages
English (en)
Other versions
DE69027962T2 (de
Inventor
Redwood City Van Taiariol
Robert Oakley
Peter Ventura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Publication of DE69027962D1 publication Critical patent/DE69027962D1/de
Application granted granted Critical
Publication of DE69027962T2 publication Critical patent/DE69027962T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/34Internal compartments or partitions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/24Gas permeable parts
DE69027962T 1989-03-10 1990-03-09 Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium Expired - Fee Related DE69027962T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/321,765 US5017490A (en) 1989-03-10 1989-03-10 Method for in vitro reproduction and growth of cells in culture medium
PCT/US1990/001318 WO1990010690A1 (en) 1989-03-10 1990-03-09 Method and apparatus for in vitro reproduction and growth of cells in culture medium

Publications (2)

Publication Number Publication Date
DE69027962D1 true DE69027962D1 (de) 1996-09-05
DE69027962T2 DE69027962T2 (de) 1997-01-02

Family

ID=23251935

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69027962T Expired - Fee Related DE69027962T2 (de) 1989-03-10 1990-03-09 Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium

Country Status (9)

Country Link
US (1) US5017490A (de)
EP (1) EP0418354B1 (de)
JP (1) JP2981684B2 (de)
AT (1) ATE140956T1 (de)
CA (1) CA2011917C (de)
DE (1) DE69027962T2 (de)
DK (1) DK0418354T3 (de)
ES (1) ES2092506T3 (de)
WO (1) WO1990010690A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4027126C1 (de) * 1990-08-28 1991-12-12 Eberhard Prof. Dr. 2000 Hamburg De Bock
EP0507933B1 (de) * 1990-10-31 1996-05-22 Baxter International Inc. Vaskularisation erlaubendes implantatmaterial
US5330915A (en) * 1991-10-18 1994-07-19 Endotronics, Inc. Pressure control system for a bioreactor
IL102189A (en) * 1992-06-12 1995-07-31 Univ Ben Gurion Device for growing microorganisms
DE4303936C1 (de) * 1993-02-10 1994-08-18 Gore W L & Ass Gmbh Vorrichtung zur Entfernung von gasförmigen Stoffen aus einem Gasstrom
ATE274340T1 (de) 1993-08-10 2004-09-15 Gore & Ass Zelleinkapselungsvorrichtung
JPH0780041A (ja) * 1993-09-20 1995-03-28 Terumo Corp 細胞保存バッグシステム
US5935847A (en) 1994-10-28 1999-08-10 Baxter International Inc. Multilayer gas-permeable container for the culture of adherent and non-adherent cells
US6297046B1 (en) 1994-10-28 2001-10-02 Baxter International Inc. Multilayer gas-permeable container for the culture of adherent and non-adherent cells
US5728581A (en) * 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
US6024220A (en) 1995-06-07 2000-02-15 Baxter International Inc. Encapsulated seam for multilayer materials
US6391404B1 (en) 1995-06-07 2002-05-21 Baxter International Inc. Coextruded multilayer film materials and containers made therefrom
WO1997010807A1 (en) * 1995-09-22 1997-03-27 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
US5964261A (en) 1996-05-29 1999-10-12 Baxter International Inc. Implantation assembly
DE19707497A1 (de) * 1996-08-16 1998-02-19 Boehringer Mannheim Gmbh Reaktionsbeutelvorrichtung zur Durchführung von mehrstufigen Kultivierungs/Separations-Vorgängen und/oder Reaktionen
ID26784A (id) * 1997-12-24 2001-02-08 Duphar Int Res Pembuatan sel-sel untuk memproduksi yang perhubungan dengan biologi
US6183460B1 (en) 1998-01-22 2001-02-06 Baxter International Inc. Multi-use solution container having flaps
US7326564B2 (en) 2001-02-20 2008-02-05 St. Jude Medical, Inc. Flow system for medical device evaluation and production
WO2005059091A1 (ja) * 2003-12-18 2005-06-30 Hitachi Medical Corporation 細胞培養装置
JP4771433B2 (ja) * 2004-02-23 2011-09-14 クレシー,ウッド,フランソワ,マリ ド より適切な細胞変異体を選択可能な移動型容器を備えた連続培養装置
EP1739165A1 (de) * 2005-06-29 2007-01-03 Cellution Biotech B.V. Verfahren und Vorrichtung zur Kultivierung von Zellen unter Verwendung von Wellenbewegung
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
US20080131960A1 (en) * 2006-11-15 2008-06-05 Millipore Corporation Self standing bioreactor construction
US20080131959A1 (en) * 2006-11-15 2008-06-05 Millipore Corporation Bioreactor construction
WO2008073313A2 (en) 2006-12-07 2008-06-19 Wilson Wolf Manufacturing Corporation Highly efficient gas permeable devices and methods for culturing cells
CN101541946B (zh) * 2007-01-22 2013-08-14 伊恩·梅尔康·莱特 体积可变化的生物反应器
JP5023795B2 (ja) * 2007-04-27 2012-09-12 東洋製罐株式会社 細胞培養方法、細胞培養システム、及び培地調整装置
US9441193B2 (en) * 2007-04-27 2016-09-13 Toyo Seikan Group Holdings, Ltd. Cell culture apparatus, cell culture system and cell culture method
US8114664B2 (en) * 2007-07-12 2012-02-14 Worcester Polytechnic Institute Scalable wall bioreactor for culture of plant and animal tissues
US8367400B2 (en) * 2008-03-21 2013-02-05 Corning Incorporated Culture vessel allowing large in situ scale up
JP5309658B2 (ja) * 2008-04-01 2013-10-09 東洋製罐グループホールディングス株式会社 培養方法、及び培養装置
JP5309657B2 (ja) * 2008-04-01 2013-10-09 東洋製罐グループホールディングス株式会社 培養容器
WO2009123173A1 (ja) * 2008-04-01 2009-10-08 東洋製罐株式会社 培養容器、培養方法、及び培養装置
US20100055764A1 (en) * 2008-08-27 2010-03-04 Martin Gregory R Cell culture apparatus and method
CN102325869A (zh) * 2009-02-18 2012-01-18 比洛克西治疗公司 用于处理生物材料的无菌生物反应器系统
US20100279354A1 (en) * 2009-04-29 2010-11-04 Evolugate, Llc Adapting microorganisms for agricultural products
JP5740841B2 (ja) * 2010-05-19 2015-07-01 東洋製罐グループホールディングス株式会社 細胞培養方法、細胞培養装置、及び細胞培養装置の制御方法
DE102014202261A1 (de) * 2014-02-07 2015-08-27 Eurozyto Gmbh Behältnis und Set zur Bereitstellung parenteraler Nahrung
JP6405690B2 (ja) * 2014-05-09 2018-10-17 東洋製罐グループホールディングス株式会社 複室培養容器、及び細胞培養方法
US10731118B2 (en) 2014-05-28 2020-08-04 Ge Healthcare Bio-Sciences Corp. Bag assembly for cultivation of cells
WO2015180908A1 (en) * 2014-05-28 2015-12-03 Ge Healthcare Bio-Sciences Ab Bag assembly for cultivation of cells
EP3252140B1 (de) 2015-01-30 2022-03-02 Toyo Seikan Group Holdings, Ltd. Zellkulturverfahren und zellkulturvorrichtung
CN107208028A (zh) * 2015-02-05 2017-09-26 通用电气公司 用于细胞培养的生物反应器系统
CN107406819A (zh) * 2015-03-20 2017-11-28 积水化学工业株式会社 微生物的培养方法及培养装置
US11566218B2 (en) 2016-07-05 2023-01-31 Global Life Sciences Solutions Usa Llc Apparatus and methods for adjustable volume cell culture
WO2019166998A1 (en) * 2018-03-02 2019-09-06 Thermo Electron Led Gmbh Single-use centrifuge containers for separating biological suspensions and methods of use
EP3650528A1 (de) * 2018-11-08 2020-05-13 Aglaris Ltd Zellkultursystem und -verfahren
WO2022261041A1 (en) * 2021-06-07 2022-12-15 Sotio Biotech Inc. Cell culture vessel for use in manufacturing cell products
GB2617629B (en) * 2022-06-29 2024-04-10 Hoxton Farms Ltd System for cell culture

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1792450A (en) * 1927-10-24 1931-02-10 Stich Eugen Process and appliance for fermenting sacchariferous liquids
US3102082A (en) * 1961-07-17 1963-08-27 John H Brewer Apparatus and method for culturing micro-organisms
US3257072A (en) * 1963-01-07 1966-06-21 Cryogenic Eng Co Whole blood storage structure
US3814395A (en) * 1964-02-27 1974-06-04 Kaelin J R Aeration plant for clarifying sewage and waste effluents
US3911918A (en) * 1972-04-13 1975-10-14 Ralph D Turner Blood collection, storage and administering bag
US3946780A (en) * 1973-01-04 1976-03-30 Sellers John C Fermentation container
US4132594A (en) * 1976-06-28 1979-01-02 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Gas diffusion liquid storage bag and method of use for storing blood
US4059486A (en) * 1976-11-03 1977-11-22 Monsanto Company Cell culture process
IT1122151B (it) * 1978-07-26 1986-04-23 Biotest Serum Institut Gmbh Sistema di sacchetti per la coltura di sangue
CS231615B1 (en) * 1981-12-29 1984-12-14 Vladislav Vlcek Method of cultivation of cells of higher organism and device to perform the method
US4507114A (en) * 1983-10-21 1985-03-26 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
US4632244A (en) * 1986-02-19 1986-12-30 Boris Landau Multiple chamber flexible container
US4829002A (en) * 1986-05-12 1989-05-09 Baxter International Inc. System for metering nutrient media to cell culture containers and method
US4734373A (en) * 1986-06-24 1988-03-29 Bartal Arie H Apparatus for enhancing cell growth, preservation and transport
US4717668A (en) * 1986-12-12 1988-01-05 Baxter Travenol Laboratories, Inc. Plastic roller bottle for suspension cultures

Also Published As

Publication number Publication date
CA2011917A1 (en) 1990-09-10
ES2092506T3 (es) 1996-12-01
EP0418354A4 (en) 1991-12-27
ATE140956T1 (de) 1996-08-15
WO1990010690A1 (en) 1990-09-20
US5017490A (en) 1991-05-21
EP0418354A1 (de) 1991-03-27
JP2981684B2 (ja) 1999-11-22
DK0418354T3 (da) 1996-08-26
CA2011917C (en) 2000-01-25
JPH03505164A (ja) 1991-11-14
DE69027962T2 (de) 1997-01-02
EP0418354B1 (de) 1996-07-31

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Legal Events

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8339 Ceased/non-payment of the annual fee